propofol has been researched along with Substance Withdrawal Syndrome in 46 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to compare the effectiveness of esmolol 1 mg/kg and lidocaine 1 mg/kg for injection pain and for the prevention of rocuronium-induced withdrawal response." | 9.20 | Effects of pretreatment with esmolol and lidocaine on injection pain and rocuronium-induced withdrawal response. ( Akinci, M; Bumin Aydin, G; Ergil, J; Gürel, A; Kavak Akelma, F; Özkan, D, 2015) |
| "Seizures or seizure-like phenomena which are mostly convulsive have been observed during the induction, maintenance and withdrawal phases of propofol administration." | 7.77 | Propofol withdrawal seizures: non-epileptic nature of seizures in a patient with recently controlled status epilepticus. ( Abou-Khalil, B; Arain, A; Patton, T; Smithson, K; Sonmezturk, HH; Zubair, S, 2011) |
| "Propofol is associated with abnormal motor events resembling seizures, the exact nature of these events remains to be elucidated." | 7.74 | Propofol withdrawal seizures (or not). ( Kaplan, PW; Zeiler, SR, 2008) |
| "We aimed to compare the effectiveness of esmolol 1 mg/kg and lidocaine 1 mg/kg for injection pain and for the prevention of rocuronium-induced withdrawal response." | 5.20 | Effects of pretreatment with esmolol and lidocaine on injection pain and rocuronium-induced withdrawal response. ( Akinci, M; Bumin Aydin, G; Ergil, J; Gürel, A; Kavak Akelma, F; Özkan, D, 2015) |
| "Seizures or seizure-like phenomena which are mostly convulsive have been observed during the induction, maintenance and withdrawal phases of propofol administration." | 3.77 | Propofol withdrawal seizures: non-epileptic nature of seizures in a patient with recently controlled status epilepticus. ( Abou-Khalil, B; Arain, A; Patton, T; Smithson, K; Sonmezturk, HH; Zubair, S, 2011) |
| "Propofol is associated with abnormal motor events resembling seizures, the exact nature of these events remains to be elucidated." | 3.74 | Propofol withdrawal seizures (or not). ( Kaplan, PW; Zeiler, SR, 2008) |
| "Patients in the ICU after long-term administration of an opioid/hypnotic often develop delirium." | 2.71 | Withdrawal following sufentanil/propofol and sufentanil/midazolam. Sedation in surgical ICU patients: correlation with central nervous parameters and endogenous opioids. ( Freye, EC; Korak-Leiter, M; Levy, JV; Likar, R; Oher, M; Trampitsch, E; Ziervogel, G, 2005) |
| "Naloxone treatment, in opioid-addicted patients, induced a marked increase in catecholamine plasma concentrations, metabolism, and cardiovascular stimulation during anesthesia with both propofol and methohexital." | 2.69 | Acute detoxification of opioid-addicted patients with naloxone during propofol or methohexital anesthesia: a comparison of withdrawal symptoms, neuroendocrine, metabolic, and cardiovascular patterns. ( Gastpar, M; Kienbaum, P; Michel, MC; Peters, J; Scherbaum, N; Thürauf, N, 2000) |
| "Propofol is a viable alternative for patients refractory to benzodiazepines; however, the role of other agents remains unclear." | 2.53 | Treatment of Severe Alcohol Withdrawal. ( Cadiz, M; Doshi, MR; Holzhausen, JM; Natavio, A; Schmidt, KJ; Winegardner, JE, 2016) |
| "Propofol has yet not arrived on the local black markets." | 2.47 | [Assessment of the addictive risk of propofol]. ( Bonnet, U, 2011) |
| "Propofol is a sedative-hypnotic prescription medication that is widely used in anesthesia, long-term sedation, and conscious sedation." | 2.46 | The abuse potential of propofol. ( Canning, P; Caravati, EM; Wilson, C, 2010) |
| "Lorazepam alone was not effective in massive doses in these cases." | 2.42 | Propofol combined with lorazepam for severe poly substance misuse and withdrawal states in intensive care unit: a case series and review. ( Gowda, RM; Jani, K; Subramaniam, K; Ute, R; Zewedie, W, 2004) |
| "Bradycardia was experienced by 11." | 1.56 | Use of Propofol Plus Dexmedetomidine in Patients Experiencing Severe Alcohol Withdrawal in the Intensive Care Unit. ( Love, K; Zimmermann, AE, 2020) |
| "Baclofen and diazepam were introduced on the third day, allowing dose reductions in anaesthetic agents the fourth day and extubation on the fifth day with resolution of the delirium." | 1.56 | Severe delirium after GHB abuse. ( Giil, LM; Sundal, EV, 2020) |
| "The chronic use of alcohol can lead to the onset of an alcohol use disorder (AUD)." | 1.51 | Diagnosis and treatment of acute alcohol intoxication and alcohol withdrawal syndrome: position paper of the Italian Society on Alcohol. ( Agabio, R; Allosio, P; Amendola, MF; Arico', S; Balbinot, P; Caputo, F; Cimarosti, P; Fanucchi, T; Greco, G; Macciò, L; Meneguzzi, C; Mioni, D; Palmieri, VO; Parisi, M; Patussi, V; Renzetti, D; Rossin, R; Scafato, E; Testino, G; Vignoli, T; Zavan, V, 2019) |
| "Treatment with carisoprodol and phenobarbital provided additional benefit and can be considered in cases of severe carisoprodol withdrawal." | 1.46 | Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose. ( Benowitz, NL; Horng, H; Smollin, CG; Vo, KT, 2017) |
| "Propofol is a widely used general anaesthetic with multisite mechanisms and especially ultrashort activation of certain central GABA-A receptors." | 1.35 | A case report of propofol dependence in a physician. ( Bonnet, U; Harkener, J; Scherbaum, N, 2008) |
| "Further studies are needed to measure withdrawal symptoms longer than one-day post detoxification and to compare the differences between various detoxification protocols." | 1.33 | Measurement of symptom withdrawal severity in a 24-hour period after the anesthesia-assisted rapid opiate detoxification procedure. ( Chaudry, S; Daiter, J; Herman, S; Raz, B; Teplin, D; Varenbut, M; Whang, P; Yung, M; Zachos, CT, 2005) |
| "Propofol therapy was begun in combination with valproic acid, fluoxetine, and risperidone to assist in the treatment of his severe agitation associated with the bipolar disease, inhibiting ventilatory weaning." | 1.32 | Propofol withdrawal syndrome in an adult patient with thermal injury. ( Ackerman, BH; Cawley, MJ; Guse, TM; Haith, LR; Laroia, A, 2003) |
| "Treatment with propofol is effective in the case of a patient with a serious withdrawal syndrome secondary to naltrexone overdose during methadone therapy." | 1.30 | Emergency therapeutical approach simulating ultrarapid opioid detoxification in methadone withdrawal precipitated by erroneous administration of naltrexone. ( Barelli, A; De Giacomo, M; Gaspari, R; Mannelli, P; Stefanelli, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (32.61) | 18.2507 |
| 2000's | 15 (32.61) | 29.6817 |
| 2010's | 13 (28.26) | 24.3611 |
| 2020's | 3 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Love, K | 1 |
| Zimmermann, AE | 1 |
| Sundal, EV | 1 |
| Giil, LM | 1 |
| Jiang, S | 1 |
| Petriceks, AH | 1 |
| Burke, H | 1 |
| Stern, TA | 1 |
| Caputo, F | 1 |
| Agabio, R | 1 |
| Vignoli, T | 1 |
| Patussi, V | 1 |
| Fanucchi, T | 1 |
| Cimarosti, P | 1 |
| Meneguzzi, C | 1 |
| Greco, G | 1 |
| Rossin, R | 1 |
| Parisi, M | 1 |
| Mioni, D | 1 |
| Arico', S | 1 |
| Palmieri, VO | 1 |
| Zavan, V | 1 |
| Allosio, P | 1 |
| Balbinot, P | 1 |
| Amendola, MF | 1 |
| Macciò, L | 1 |
| Renzetti, D | 1 |
| Scafato, E | 1 |
| Testino, G | 1 |
| Sohraby, R | 1 |
| Attridge, RL | 1 |
| Hughes, DW | 1 |
| Wong, A | 1 |
| Benedict, NJ | 1 |
| Lohr, BR | 1 |
| Pizon, AF | 2 |
| Kane-Gill, SL | 1 |
| Ergil, J | 1 |
| Kavak Akelma, F | 1 |
| Özkan, D | 1 |
| Bumin Aydin, G | 1 |
| Gürel, A | 1 |
| Akinci, M | 1 |
| Stewart, R | 1 |
| Perez, R | 1 |
| Musial, B | 1 |
| Lukens, C | 1 |
| Adjepong, YA | 1 |
| Manthous, CA | 1 |
| Schmidt, KJ | 1 |
| Doshi, MR | 1 |
| Holzhausen, JM | 1 |
| Natavio, A | 1 |
| Cadiz, M | 1 |
| Winegardner, JE | 1 |
| Vo, KT | 1 |
| Horng, H | 1 |
| Smollin, CG | 1 |
| Benowitz, NL | 1 |
| Liatsi, D | 1 |
| Tsapas, B | 1 |
| Pampori, S | 1 |
| Tsagourias, M | 1 |
| Pneumatikos, I | 1 |
| Matamis, D | 1 |
| Bonnet, U | 2 |
| Harkener, J | 1 |
| Scherbaum, N | 2 |
| Wilson, C | 1 |
| Canning, P | 1 |
| Caravati, EM | 1 |
| Devlin, JW | 1 |
| Mallow-Corbett, S | 1 |
| Riker, RR | 1 |
| Zubair, S | 1 |
| Patton, T | 1 |
| Smithson, K | 1 |
| Sonmezturk, HH | 1 |
| Arain, A | 1 |
| Abou-Khalil, B | 1 |
| Stein, M | 1 |
| Schomacher, J | 1 |
| Scharbrodt, W | 1 |
| Preuss, M | 1 |
| Oertel, MF | 1 |
| Cawley, MJ | 1 |
| Guse, TM | 1 |
| Laroia, A | 1 |
| Haith, LR | 1 |
| Ackerman, BH | 1 |
| Subramaniam, K | 2 |
| Gowda, RM | 2 |
| Rosa, U | 1 |
| Freye, E | 1 |
| Levy, JV | 2 |
| Partecke, L | 1 |
| Jani, K | 1 |
| Zewedie, W | 1 |
| Ute, R | 1 |
| Korak-Leiter, M | 1 |
| Likar, R | 1 |
| Oher, M | 1 |
| Trampitsch, E | 1 |
| Ziervogel, G | 1 |
| Freye, EC | 1 |
| Teplin, D | 1 |
| Raz, B | 1 |
| Daiter, J | 1 |
| Varenbut, M | 1 |
| Zachos, CT | 1 |
| Whang, P | 1 |
| Herman, S | 1 |
| Chaudry, S | 1 |
| Yung, M | 1 |
| Zapantis, A | 1 |
| Leung, S | 1 |
| Ackland, GL | 1 |
| Fox, R | 1 |
| Rosen, DA | 1 |
| Lovecchio, F | 1 |
| Zeiler, SR | 1 |
| Kaplan, PW | 1 |
| Valente, JF | 1 |
| Anderson, GL | 1 |
| Branson, RD | 1 |
| Johnson, DJ | 1 |
| Davis, K | 1 |
| Porembka, DT | 1 |
| Bartter, T | 1 |
| Gooberman, LL | 1 |
| Demaria, PA | 2 |
| Rodgers, C | 1 |
| Braccia, G | 1 |
| Currier, DS | 1 |
| Bevacqua, BK | 1 |
| Dirksen, R | 1 |
| Ellenbroek, B | 1 |
| van Egmond, J | 1 |
| Cools, AR | 1 |
| Papadimos, TJ | 1 |
| Murray, MJ | 1 |
| Cammarano, WB | 1 |
| Pittet, JF | 1 |
| Weitz, S | 1 |
| Schlobohm, RM | 1 |
| Marks, JD | 1 |
| Lappin, R | 1 |
| McDonald, T | 2 |
| Hoffman, WE | 2 |
| Berkowitz, R | 2 |
| Cunningham, F | 1 |
| Cooke, B | 1 |
| De Giacomo, M | 1 |
| Gaspari, R | 1 |
| Stefanelli, A | 1 |
| Barelli, A | 1 |
| Mannelli, P | 1 |
| Hensel, M | 1 |
| Wolter, S | 1 |
| Kox, WJ | 1 |
| Wilson, LB | 1 |
| Kane, HL | 1 |
| Reining, KM | 1 |
| Kienbaum, P | 1 |
| Thürauf, N | 1 |
| Michel, MC | 1 |
| Gastpar, M | 1 |
| Peters, J | 1 |
| Imray, JM | 1 |
| Hay, A | 1 |
| Grant, IS | 1 |
| Worsley, M | 1 |
| Au, J | 1 |
| Walker, WS | 1 |
| Scott, DH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| Effect of Clonidine vs. Dexmedetomidine in Addition to Standard Treatment in Agitated Delirium in Intensive Care Patients: Pilot Study.[NCT04758936] | Phase 4 | 50 participants (Anticipated) | Interventional | 2021-02-01 | Recruiting | ||
| Opioid Withdrawal Symptoms in Critically Ill Patients[NCT03374722] | 55 participants (Actual) | Observational | 2018-01-01 | Completed | |||
| Ketamine Tolerance in Children After Repeated Administrations During Radiotherapy Sessions[NCT02512055] | Phase 4 | 33 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
| Opioids Withdrawal Syndrome in Critically Ill Patients: a Multicenter Prospective Cohort Study[NCT02318290] | 54 participants (Actual) | Observational | 2015-01-31 | Completed | |||
| Signs and Symptoms of Opioid-associated Iatrogenic Withdrawal in Critically Ill Adults[NCT03435614] | 29 participants (Actual) | Observational | 2018-02-26 | Completed | |||
| Assessing Current Analgesia and Sedation Weaning Practices in Adult Critically Ill Patients[NCT04422808] | 2,437 participants (Actual) | Observational | 2021-06-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Percentage of daily assessments associated with each of the following signs and symptoms experienced by patients with and without OIWS (Restlessness (Richmond Agitation-Sedation scale = 1), Agitation (RASS > 1), Anxiety, Hallucinations, Insomnia/sleep disturbance (< 4 hours of continuous sleep), Mydriasis (Pupil diameter > 2 mm) and systolic blood pressure (SBP) > 140 mmHg. These assessments were performed once daily.~Note that for the group of patients experiencing IWS, the data on signs and symptoms are limited to the assessment on the day that patients experienced OIWS.~The signs and symptoms presented (Restlessness; Agitation; Anxiety, Hallucinations, Insomnia/sleep disturbance; mydriasis; SBP > 140) were selected based on a > 15 % absolute difference between both groups which was judged to be clinically significant." (NCT03435614)
Timeframe: From first day of opioid dose reduction until transfer out of Intensive care unit (ICU) or a maximum of 14 days, including one further assessment post-ICU transfer
| Intervention | percentage of assessments (Number) | ||||||
|---|---|---|---|---|---|---|---|
| Restlessness (RASS = 1) | Agitation (RASS > 1) | Anxiety | Hallucinations | Insomnia/Sleep disturbance (< 4 hours of continuous sleep) | Mydriasis (pupil size > 2mm) | Systolic Blood Pressure (SBP) > 140 mmHg | |
| IWS Negative | 13.6 | 4.9 | 30.6 | 11.2 | 21.4 | 77.8 | 53 |
| IWS Positive | 28.6 | 28.6 | 57.1 | 28.6 | 66.7 | 100 | 85.7 |
8 reviews available for propofol and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Treatment of Severe Alcohol Withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Critical Care; Dexmedetomidine; Drug Thera | 2016 |
The abuse potential of propofol.
Topics: Anesthetics, Intravenous; Animals; Drug and Narcotic Control; Drug Tolerance; Humans; Propofol; Subs | 2010 |
Adverse drug events associated with the use of analgesics, sedatives, and antipsychotics in the intensive care unit.
Topics: Acidosis; Analgesics; Antipsychotic Agents; Bradycardia; Cardiovascular Diseases; Critical Care; Dru | 2010 |
[Assessment of the addictive risk of propofol].
Topics: Administration, Oral; Anesthetics, Intravenous; Animals; Disease Models, Animal; Electroconvulsive T | 2011 |
Propofol combined with lorazepam for severe poly substance misuse and withdrawal states in intensive care unit: a case series and review.
Topics: Adult; Anesthetics, Intravenous; Critical Care; Drug Therapy, Combination; Female; Humans; Hypnotics | 2004 |
Tolerance and withdrawal issues with sedation.
Topics: Analgesics; Benzodiazepines; Biological Availability; Conscious Sedation; Critical Care; Dexmedetomi | 2005 |
Unintended consequences.
Topics: Animals; Humans; Neuromuscular Blocking Agents; Propofol; Substance Withdrawal Syndrome | 1998 |
Anesthesia-assisted rapid opiate detoxification: a new procedure in the postanesthesia care unit.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Heroin Dependence; Humans; Male; Midazolam; Na | 1999 |
5 trials available for propofol and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Effects of pretreatment with esmolol and lidocaine on injection pain and rocuronium-induced withdrawal response.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Androstanols; Anesthesia, General; Anesthetics, Intra | 2015 |
Use of gabapentin for attenuation of symptoms following rapid opiate detoxification (ROD)--correlation with neurophysiological parameters--.
Topics: Acetates; Adult; Amines; Anesthesia; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Electric | 2004 |
Withdrawal following sufentanil/propofol and sufentanil/midazolam. Sedation in surgical ICU patients: correlation with central nervous parameters and endogenous opioids.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; beta-Endorphin; Blood Pressure; Conscious Sedation; Cri | 2005 |
EEG controlled rapid opioid withdrawal under general anaesthesia.
Topics: Anesthesia, General; Anesthetics, Intravenous; Electroencephalography; Female; Humans; Male; Monitor | 2000 |
Acute detoxification of opioid-addicted patients with naloxone during propofol or methohexital anesthesia: a comparison of withdrawal symptoms, neuroendocrine, metabolic, and cardiovascular patterns.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Catecholamines; Female; Humans; Male; Methadon | 2000 |
33 other studies available for propofol and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Use of Propofol Plus Dexmedetomidine in Patients Experiencing Severe Alcohol Withdrawal in the Intensive Care Unit.
Topics: Alcoholism; Bradycardia; Critical Care; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; | 2020 |
Severe delirium after GHB abuse.
Topics: Baclofen; Delirium; Female; Humans; Propofol; Sodium Oxybate; Substance Withdrawal Syndrome | 2020 |
Weaning From Exogenous Sedation in the Era of COVID-19 Infection: Recommendations for Sedation and Its Discontinuation.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Betacoronavirus; Coronavirus Infections; COVID-19; Depre | 2020 |
Diagnosis and treatment of acute alcohol intoxication and alcohol withdrawal syndrome: position paper of the Italian Society on Alcohol.
Topics: Alcoholic Intoxication; Anticonvulsants; Benzodiazepines; Chlormethiazole; Humans; Phenobarbital; Pr | 2019 |
Use of propofol-containing versus benzodiazepine regimens for alcohol withdrawal requiring mechanical ventilation.
Topics: Adult; Benzodiazepines; Ethanol; Female; Humans; Hypnotics and Sedatives; Length of Stay; Lorazepam; | 2014 |
Management of benzodiazepine-resistant alcohol withdrawal across a healthcare system: Benzodiazepine dose-escalation with or without propofol.
Topics: Adult; Benzodiazepines; Diazepam; Drug Resistance; Drug Therapy, Combination; Ethanol; Female; Human | 2015 |
Outcomes of Patients with Alcohol Withdrawal Syndrome Treated with High-Dose Sedatives and Deferred Intubation.
Topics: Adult; Alcohol Withdrawal Seizures; APACHE; Central Nervous System Depressants; Cohort Studies; Crit | 2016 |
Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose.
Topics: Adult; Carisoprodol; Dexmedetomidine; Drug Overdose; Fentanyl; Haloperidol; Humans; Hypnotics and Se | 2017 |
Respiratory, metabolic and hemodynamic effects of clonidine in ventilated patients presenting with withdrawal syndrome.
Topics: Adrenergic alpha-Agonists; Adult; Calorimetry, Indirect; Carbon Dioxide; Clonidine; Electrocardiogra | 2009 |
A case report of propofol dependence in a physician.
Topics: Adult; Anesthetics, Intravenous; Diagnosis, Differential; Dose-Response Relationship, Drug; Humans; | 2008 |
Propofol withdrawal seizures: non-epileptic nature of seizures in a patient with recently controlled status epilepticus.
Topics: Adult; Electroencephalography; Female; Humans; Propofol; Seizures; Status Epilepticus; Substance Wit | 2011 |
Cerebrospinal fluid lactate concentration after withdrawal of metabolic suppressive therapy in subarachnoid hemorrhage.
Topics: Adult; Aged; Female; Fentanyl; Glasgow Outcome Scale; Humans; Hypnotics and Sedatives; Intensive Car | 2012 |
NY: AROD anesthesia allegedly caused death: denial of motion for summary judgment affirmed. Dmytryszyn v. Herschman, 2012-06061 NYAPP2 (8/29/2012)-NY.
Topics: Anesthetics, Intravenous; Humans; Malpractice; New York; Propofol; Substance Withdrawal Syndrome | 2012 |
Propofol withdrawal syndrome in an adult patient with thermal injury.
Topics: Bipolar Disorder; Burns; Ethanol; Fatal Outcome; Humans; Hypnotics and Sedatives; Male; Middle Aged; | 2003 |
Delayed neuroexcitatory symptoms following propofol sedation in a patient with polysubstance abuse.
Topics: Akathisia, Drug-Induced; Alcoholism; Conscious Sedation; Electroencephalography; Humans; Hypnotics a | 2003 |
Measurement of symptom withdrawal severity in a 24-hour period after the anesthesia-assisted rapid opiate detoxification procedure.
Topics: Adult; Anesthetics, Intravenous; Clinical Protocols; Drug Monitoring; Drug Therapy, Combination; Fem | 2005 |
Low-dose propofol infusion for controlling acute hyperspasticity after withdrawal of intrathecal baclofen therapy.
Topics: Acute Disease; Adult; Aged; Baclofen; Drug Hypersensitivity; Humans; Injections, Spinal; Male; Muscl | 2005 |
Medications to provide cooperation in the critically ill pediatric patient: a rose with a thorn.
Topics: Adrenergic alpha-Agonists; Adult; Child; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Se | 2005 |
Reversible cardiomyopathy complicating intrathecal baclofen withdrawal: a case report.
Topics: Baclofen; Cardiomyopathies; Drug Therapy, Combination; Humans; Infusion Pumps, Implantable; Injectio | 2007 |
Propofol withdrawal seizures (or not).
Topics: Conscious Sedation; Female; Foot Deformities; Humans; Middle Aged; Propofol; Seizures; Substance Wit | 2008 |
Disadvantages of prolonged propofol sedation in the critical care unit.
Topics: Adult; Critical Care; Female; Humans; Intensive Care Units; Postoperative Complications; Propofol; R | 1994 |
Rapid opiate detoxification.
Topics: Adult; Anesthetics, Intravenous; Critical Care; Female; Heroin Dependence; Humans; Hypnotics and Sed | 1996 |
Propofol for sedation during rapid opiate detoxification.
Topics: Adult; Clonidine; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Naloxone; Opioid-Re | 1997 |
Acute tachyphylaxis to propofol sedation during ethanol withdrawal.
Topics: Acute Disease; Ethanol; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Substance With | 1997 |
Responses to propofol in relation to GABA functionality of discrete parts of the brain of rats.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Apomorphine; Behavior, Animal; Blood Pre | 1997 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Topics: Acute Disease; Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Dose-Response | 1998 |
Propofol in delirium tremens.
Topics: Alcohol Withdrawal Delirium; Diagnosis, Differential; Ethanol; Humans; Hypnotics and Sedatives; Male | 1998 |
Heart rate variability and plasma catecholamines in patients during opioid detoxification.
Topics: Adult; Analysis of Variance; Anesthetics, Intravenous; Blood Pressure; Electroencephalography; Epine | 1999 |
Emergency therapeutical approach simulating ultrarapid opioid detoxification in methadone withdrawal precipitated by erroneous administration of naltrexone.
Topics: Adult; Anesthetics, Intravenous; Emergencies; Humans; Male; Methadone; Naltrexone; Narcotic Antagoni | 1999 |
Median EEG frequency is more sensitive to increases in sympathetic activity than bispectral index.
Topics: Anesthesia, Intravenous; Electroencephalography; Heart Rate; Humans; Naloxone; Opioid-Related Disord | 1999 |
Withdrawal syndrome after propofol.
Topics: Akathisia, Drug-Induced; Female; Humans; Infant; Propofol; Substance Withdrawal Syndrome | 1991 |
Withdrawal syndrome after propofol.
Topics: Anesthesia, Intravenous; Humans; Propofol; Seizures; Substance Withdrawal Syndrome | 1991 |
Withdrawal syndrome after propofol infusion.
Topics: Adult; Cardiac Surgical Procedures; Coronary Care Units; Epilepsy, Tonic-Clonic; Humans; Male; Posto | 1990 |