Page last updated: 2024-11-03

propofol and Stiff-Person Syndrome

propofol has been researched along with Stiff-Person Syndrome in 13 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Stiff-Person Syndrome: A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93)

Research Excerpts

ExcerptRelevanceReference
"This hypotonia has been linked to muscle relaxants and volatile anesthetics and may persist in spite of neostigmine administration and train-of-four (TOF) monitoring suggesting full reversal."2.82Postoperative hypotonia in a patient with stiff person syndrome: a case report and literature review. ( Backman, SB; Elsherbini, N; Weingartshofer, A, 2022)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (61.54)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Elsherbini, N1
Weingartshofer, A1
Backman, SB1
Gharedaghi, MH1
Khorasani, A1
Knezevic, NN1
Ebrahimi, F1
Lynagh, T1
Kunz, A1
Laube, B1
Sidransky, MA1
Tran, NV1
Kaye, AD1
Cassavaugh, JM1
Oravitz, TM1
Aya, D1
Fukuda, T1
Ohkoshi, N1
Furukawa, H1
Toyooka, H1
Ferrandis, R1
Belda, J1
Llau, JV1
Belda, C1
Bahamonde, JA1
Elkassabany, N1
Tetzlaff, JE1
Argalious, M1
Ledowski, T1
Russell, P1
Hattan, E1
Angle, MR1
Chalk, C1
Aoki, Y1
Shakunaga, K1
Asahi, T1
Sasaki, R1
Murahana, J1
Hatakeyama, N1
Yamazaki, M1
Vernino, S1
McEvoy, K1
Obara, M1
Sawamura, S1
Chinzei, M1
Komatsu, K1
Hanaoka, K1

Reviews

1 review available for propofol and Stiff-Person Syndrome

ArticleYear
Postoperative hypotonia in a patient with stiff person syndrome: a case report and literature review.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2022, Volume: 69, Issue:11

    Topics: Anesthetics, Inhalation; Chelating Agents; Cholinesterase Inhibitors; Female; Humans; Muscle Hypoton

2022

Other Studies

12 other studies available for propofol and Stiff-Person Syndrome

ArticleYear
Anaesthetic management of a patient with a unique combination of anti-N-methyl-D-aspartate receptor encephalitis and stiff-person syndrome.
    BMJ case reports, 2018, May-07, Volume: 2018

    Topics: Administration, Intravenous; Adult; Anesthesia, General; Anesthetics; Anti-N-Methyl-D-Aspartate Rece

2018
Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activation.
    ACS chemical neuroscience, 2013, Nov-20, Volume: 4, Issue:11

    Topics: Anesthetics, Intravenous; Animals; Disulfides; Dithiothreitol; Humans; Ligand-Gated Ion Channels; Mu

2013
Anesthesia considerations in stiff person syndrome.
    Middle East journal of anaesthesiology, 2013, Volume: 22, Issue:2

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Catheters, Indwelling; Humans; Lidocaine; Male;

2013
Multiple anesthetics for a patient with stiff-person syndrome.
    Journal of clinical anesthesia, 2016, Volume: 31

    Topics: Androstanols; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Fentan

2016
[Regional anesthesia for a patient with stiff-person syndrome].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:1

    Topics: Aged; Anesthesia, Conduction; Bradycardia; Humans; Lidocaine; Male; Pacemaker, Artificial; Propofol;

2004
Anesthesia for cardiac surgery on a patient with stiff person syndrome.
    Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:3

    Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Anticonvulsants; Cardiopulmonary By

2005
Anesthetic management of a patient with stiff person syndrome.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:3

    Topics: Adjuvants, Anesthesia; Aged; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Fentanyl; He

2006
Anaesthesia for stiff person syndrome: successful use of total intravenous anaesthesia.
    Anaesthesia, 2006, Volume: 61, Issue:7

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Humans; Male; Propofol; Stiff-Person Syndro

2006
Unexpected benefit of propofol in stiff-person syndrome.
    Neurology, 2008, Apr-29, Volume: 70, Issue:18

    Topics: Aged; Autoantibodies; Baclofen; Diazepam; Drug Resistance; Female; GABA Agonists; GABA-A Receptor Ag

2008
[Anesthesia for a patient with stiff-person syndrome].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:4

    Topics: Anesthesia, Intravenous; Axilla; Electric Stimulation; Female; Humans; Lymph Node Excision; Lymph No

2008
Propofol for stiff-person syndrome: learning new tricks from an old dog.
    Neurology, 2008, Apr-29, Volume: 70, Issue:18

    Topics: Aged; Autoantibodies; Baclofen; Diazepam; Drug Resistance; Female; GABA Agonists; GABA-A Receptor Ag

2008
Anaesthetic management of a patient with Stiff-person syndrome.
    Anaesthesia, 2002, Volume: 57, Issue:5

    Topics: Adult; Anesthesia; Female; Humans; Isoflurane; Propofol; Reoperation; Stiff-Person Syndrome

2002