propofol has been researched along with Spinal Diseases in 13 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Spinal Diseases: Diseases involving the SPINE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized, placebo-controlled, double-blind study to evaluate the effect of intravenously (IV) administered acetaminophen on postoperative pain in children and adolescents undergoing surgery for idiopathic scoliosis or spondylolisthesis." | 5.16 | Acetaminophen improves analgesia but does not reduce opioid requirement after major spine surgery in children and adolescents. ( Hartikainen, T; Helenius, I; Hiller, A; Kaukonen, M; Korpela, R; Meretoja, OA; Neuvonen, PJ; Nurmi, E; Taivainen, T, 2012) |
| "The results suggest that, using a transcranial multipulse stimulation, monitoring of motor-evoked potentials from the external anal sphincter is feasible during ketamine- and propofol-based anesthesia." | 5.10 | Intraoperative monitoring of myogenic motor-evoked potentials from the external anal sphincter muscle to transcranial electrical stimulation. ( Furuya, H; Inoue, S; Kakimoto, M; Kawaguchi, M; Kitaguchi, K; Morimoto, T; Sakaki, T; Sakamoto, T; Takashi, S, 2002) |
| "The study group included patients with supratentorial tumors undergoing craniotomy, and the control group consisted of patients undergoing spinal surgeries." | 2.77 | Fentanyl co-administration decreases the induction dose requirement of propofol in patients with supratentorial tumors and not in patients with spinal lesions. ( Bansal, S; Ramesh, VJ; Umamaheswara Rao, GS, 2012) |
| "Propofol was replaced with ketamine if no reliable MEPs could be recorded." | 2.73 | Intraoperative monitoring of motor-evoked potentials in children undergoing spinal surgery. ( Duitmann, E; Erb, TO; Frei, FJ; Hasler, CC; Luetschg, J; Ryhult, SE, 2007) |
| "Ketamine has been reported to have little effect on MEPs but may produce adverse effects such as psychedelic effect and hypertension." | 1.31 | Low dose propofol as a supplement to ketamine-based anesthesia during intraoperative monitoring of motor-evoked potentials. ( Furuya, H; Inoue, S; Kakimoto, M; Kawaguchi, M; Morimoto, T; Sakaki, T; Sakamoto, T, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z | 2 |
| Dai, N | 1 |
| Lin, S | 1 |
| Zhou, G | 1 |
| Jahangiri, FR | 1 |
| Sheryar, M | 1 |
| Al Okaili, R | 1 |
| Hiller, A | 1 |
| Helenius, I | 1 |
| Nurmi, E | 1 |
| Neuvonen, PJ | 1 |
| Kaukonen, M | 1 |
| Hartikainen, T | 1 |
| Korpela, R | 1 |
| Taivainen, T | 1 |
| Meretoja, OA | 1 |
| Bansal, S | 1 |
| Ramesh, VJ | 1 |
| Umamaheswara Rao, GS | 1 |
| Chowdhury, T | 1 |
| Cappellani, RB | 1 |
| Inoue, S | 2 |
| Kawaguchi, M | 2 |
| Takashi, S | 1 |
| Kakimoto, M | 2 |
| Sakamoto, T | 2 |
| Kitaguchi, K | 1 |
| Furuya, H | 2 |
| Morimoto, T | 2 |
| Sakaki, T | 2 |
| Frei, FJ | 1 |
| Ryhult, SE | 1 |
| Duitmann, E | 1 |
| Hasler, CC | 1 |
| Luetschg, J | 1 |
| Erb, TO | 1 |
| Diéguez, P | 1 |
| García, B | 1 |
| Pato, O | 1 |
| Santelesforo, F | 1 |
| Jorgensen, BG | 1 |
| Laub, M | 1 |
| Knudsen, RH | 1 |
| Pelosi, L | 1 |
| Stevenson, M | 1 |
| Hobbs, GJ | 1 |
| Jardine, A | 1 |
| Webb, JK | 1 |
| MacKenzie, RE | 1 |
| McFadzean, WA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Study Comparing Total Intravenous Anesthesia With Propofol and Remifentanil vs. Propofol and Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion and Instrumentation[NCT06096181] | Phase 2 | 120 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery (IGNITE-AIS Study)[NCT04931433] | Phase 4 | 102 participants (Anticipated) | Interventional | 2020-12-24 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for propofol and Spinal Diseases
| Article | Year |
|---|---|
Impact of Dexmedetomidine on Intraoperative Wake-Up Tests in Patients Undergoing Spinal Surgery.
Topics: Adult; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intraoperative Period; Male; Middle | 2018 |
Acetaminophen improves analgesia but does not reduce opioid requirement after major spine surgery in children and adolescents.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid | 2012 |
Fentanyl co-administration decreases the induction dose requirement of propofol in patients with supratentorial tumors and not in patients with spinal lesions.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Craniotomy; Female; Fentanyl; Glasgow Coma | 2012 |
Intraoperative monitoring of myogenic motor-evoked potentials from the external anal sphincter muscle to transcranial electrical stimulation.
Topics: Adolescent; Adult; Anal Canal; Anesthesia; Brain; Electric Stimulation; Evoked Potentials, Motor; Fe | 2002 |
The effects of isoflurane and propofol on intraoperative neurophysiological monitoring during spinal surgery.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Dose-Response Relationship, Dr | 2004 |
Intraoperative monitoring of motor-evoked potentials in children undergoing spinal surgery.
Topics: Adolescent; Anesthetics, Intravenous; Child; Child, Preschool; Electric Stimulation; Evoked Potentia | 2007 |
7 other studies available for propofol and Spinal Diseases
| Article | Year |
|---|---|
Neurophysiological monitoring of the spinal sensory and motor pathways during embolization of spinal arteriovenous malformations--propofol: a safe alternative.
Topics: Adult; Afferent Pathways; Anesthetics, Intravenous; Arteriovenous Malformations; Efferent Pathways; | 2014 |
Role of fentanyl in supratentorial tumor: can it change the requirement of propofol?
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Fentanyl; Humans; Male; Propofol; Spinal | 2013 |
[Continuous positive airway pressure with a helmet during sedation for vertebroplasty in a patient with severe pulmonary emphysema].
Topics: Adrenal Cortex Hormones; Aged; Anesthetics, Intravenous; Bone Cements; Conscious Sedation; Continuou | 2007 |
Anaesthetic implications of rigid spine syndrome.
Topics: Adolescent; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Contracture; Fem | 1999 |
Low dose propofol as a supplement to ketamine-based anesthesia during intraoperative monitoring of motor-evoked potentials.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Bra | 2000 |
Intraoperative motor evoked potentials to transcranial electrical stimulation during two anaesthetic regimens.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Electric Stimulat | 2001 |
A difficult airway managed by computer?
Topics: Adult; Anesthesia, Intravenous; Computers; Female; Humans; Larynx; Masks; Propofol; Spinal Diseases | 1992 |