Page last updated: 2024-11-03

propofol and Sleep Wake Disorders

propofol has been researched along with Sleep Wake Disorders in 7 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.

Research Excerpts

ExcerptRelevanceReference
"To assess and compare the impact of overnight sedation with midazolam or propofol on anxiety and depression levels, as well as sleep quality, in non-intubated patients in intensive care."9.08Overnight sedation with midazolam or propofol in the ICU: effects on sleep quality, anxiety and depression. ( Borgeat, A; Fuchs-Buder, T; Gachoud, JP; Suter, PM; Treggiari-Venzi, M, 1996)
"We investigated the efficacy and untoward effects of low doses of propofol for intrathecal morphine-induced pruritus."9.08[The efficacy of low-dose propofol for intrathecal morphine-induced pruritus]. ( Iwasaki, H; Naganuma, R; Namiki, A; Okanuma, M; Tsuchida, H, 1998)
"In total, 39 infants 4-6-mo-old were prospectively enrolled and randomized to receive either a combination of propofol and remifentanil (n = 17) or sevoflurane and fentanyl anesthesia (n = 22) for surgical repair of cleft lip-gum-palate."5.12Quality differences in postoperative sleep between propofol-remifentanil and sevoflurane anesthesia in infants. ( Eriksen, K; Holm-Knudsen, R; Marxen, D; Rasmussen, LS; Steinmetz, J, 2007)
"To assess and compare the impact of overnight sedation with midazolam or propofol on anxiety and depression levels, as well as sleep quality, in non-intubated patients in intensive care."5.08Overnight sedation with midazolam or propofol in the ICU: effects on sleep quality, anxiety and depression. ( Borgeat, A; Fuchs-Buder, T; Gachoud, JP; Suter, PM; Treggiari-Venzi, M, 1996)
"We investigated the efficacy and untoward effects of low doses of propofol for intrathecal morphine-induced pruritus."5.08[The efficacy of low-dose propofol for intrathecal morphine-induced pruritus]. ( Iwasaki, H; Naganuma, R; Namiki, A; Okanuma, M; Tsuchida, H, 1998)
"Melatonin pretreatment could restore circadian rhythm process by regulating circadian factor expression through post-translational modulation and prohibit the over-synthesis of melatonin in pineal gland."1.72Melatonin pretreatment prevents propofol-induced sleep disturbance by modulating circadian rhythm in rats. ( Dong, HJ; Li, JC; Li, S; Li, Y; Wang, HL; Xue, R; Yin, XL; Zhang, Y; Zhang, YZ, 2022)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Yin, XL1
Li, JC1
Xue, R1
Li, S1
Zhang, Y1
Dong, HJ1
Li, Y1
Wang, HL1
Zhang, YZ1
Lei, M1
Zhang, P1
Liu, Y1
Fu, F1
Ye, L1
Zhu, T1
Morena, M1
Berardi, A1
Peloso, A1
Valeri, D1
Palmery, M1
Trezza, V1
Schelling, G1
Campolongo, P1
Kondili, E1
Alexopoulou, C1
Xirouchaki, N1
Georgopoulos, D1
Steinmetz, J1
Holm-Knudsen, R1
Eriksen, K1
Marxen, D1
Rasmussen, LS1
Treggiari-Venzi, M1
Borgeat, A1
Fuchs-Buder, T1
Gachoud, JP1
Suter, PM1
Naganuma, R1
Tsuchida, H1
Okanuma, M1
Iwasaki, H1
Namiki, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Low-dose Dexmedetomidine on Outcomes of Elderly Admitted to ICU After Noncardiac Surgery: a Randomized Controlled Trial[NCT04204798]1,410 participants (Anticipated)Interventional2020-08-28Recruiting
The Effect of Two Different General Anesthesia Regimes on Postoperative Sleep Quality[NCT02061514]80 participants (Anticipated)Interventional2014-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for propofol and Sleep Wake Disorders

ArticleYear
Propofol and sufentanil may affect the patients' sleep quality independently of the surgical stress response: a prospective nonrandomized controlled trial in 1033 patients' undergone diagnostic upper gastrointestinal endoscopy.
    BMC anesthesiology, 2017, 03-31, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Endoscopy, Gastrointestinal; F

2017
Effects of propofol on sleep quality in mechanically ventilated critically ill patients: a physiological study.
    Intensive care medicine, 2012, Volume: 38, Issue:10

    Topics: Adult; Aged; Critical Care; Critical Illness; Cross-Over Studies; Female; Humans; Hypnotics and Seda

2012
Quality differences in postoperative sleep between propofol-remifentanil and sevoflurane anesthesia in infants.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Cleft Lip; Cleft Palate; F

2007
Overnight sedation with midazolam or propofol in the ICU: effects on sleep quality, anxiety and depression.
    Intensive care medicine, 1996, Volume: 22, Issue:11

    Topics: Adult; Aged; Anxiety; Critical Care; Depression; Female; Hemodynamics; Humans; Hypnotics and Sedativ

1996
[The efficacy of low-dose propofol for intrathecal morphine-induced pruritus].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:5

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Spinal; Female; Genital Diseases, Female; Humans; Hypno

1998

Other Studies

2 other studies available for propofol and Sleep Wake Disorders

ArticleYear
Melatonin pretreatment prevents propofol-induced sleep disturbance by modulating circadian rhythm in rats.
    Experimental neurology, 2022, Volume: 354

    Topics: Animals; Circadian Rhythm; Glycogen Synthase Kinase 3 beta; Humans; Melatonin; Propofol; Rats; Sleep

2022
Effects of ketamine, dexmedetomidine and propofol anesthesia on emotional memory consolidation in rats: Consequences for the development of post-traumatic stress disorder.
    Behavioural brain research, 2017, 06-30, Volume: 329

    Topics: Animals; Avoidance Learning; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Dr

2017