Page last updated: 2024-11-03

propofol and Serotonin Syndrome

propofol has been researched along with Serotonin Syndrome in 5 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"We present 3 cases of severe serotonin syndrome in adolescents requiring intubation that were refractory to midazolam and/or propofol."7.80Dexmedetomidine in the treatment of serotonin syndrome. ( Charlton, NP; Rushton, WF, 2014)
"A patient who manifested signs of serotonin syndrome during an intravenous anesthetic with remifentanil and propofol is presented."7.79Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil. ( Buck, NS; Davis, JJ; Greis, PE; Johnson, KB; Swenson, JD, 2013)
"An 18-year-old male developed a severe serotonin syndrome after recreational ingestion of Coricidin HBP (chlorpheniramine 4 mg and dextromethorphan hydrobromide 30 mg)."7.74Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy. ( Babu, KM; Boyer, EW; Ganetsky, M, 2007)
"We present 3 cases of severe serotonin syndrome in adolescents requiring intubation that were refractory to midazolam and/or propofol."3.80Dexmedetomidine in the treatment of serotonin syndrome. ( Charlton, NP; Rushton, WF, 2014)
"A patient who manifested signs of serotonin syndrome during an intravenous anesthetic with remifentanil and propofol is presented."3.79Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil. ( Buck, NS; Davis, JJ; Greis, PE; Johnson, KB; Swenson, JD, 2013)
"An 18-year-old male developed a severe serotonin syndrome after recreational ingestion of Coricidin HBP (chlorpheniramine 4 mg and dextromethorphan hydrobromide 30 mg)."3.74Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy. ( Babu, KM; Boyer, EW; Ganetsky, M, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dudum, R1
Aslam, MI1
Madrazo, J1
Rushton, WF1
Charlton, NP1
Davis, JJ1
Buck, NS1
Swenson, JD1
Johnson, KB1
Greis, PE1
Claassen, JA1
Gelissen, HP1
Ganetsky, M1
Babu, KM1
Boyer, EW1

Other Studies

5 other studies available for propofol and Serotonin Syndrome

ArticleYear
Serotonin Syndrome Masquerading as Ventricular Tachycardia Storm.
    The American journal of medicine, 2018, Volume: 131, Issue:12

    Topics: Benzodiazepines; Female; Humans; Hypnotics and Sedatives; Middle Aged; Propofol; Serotonin Agents; S

2018
Dexmedetomidine in the treatment of serotonin syndrome.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:12

    Topics: Adolescent; Adrenergic alpha-Agonists; Benzodiazepines; Dexmedetomidine; Female; Humans; Hypnotics a

2014
Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:1

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Fluoxetine; Humans; Intraoperative Complications;

2013
The serotonin syndrome.
    The New England journal of medicine, 2005, Jun-09, Volume: 352, Issue:23

    Topics: Aged; Androstanols; Combined Modality Therapy; Cyclohexanols; Humans; Hypnotics and Sedatives; Male;

2005
Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy.
    Pediatric emergency care, 2007, Volume: 23, Issue:11

    Topics: Acetaminophen; Adolescent; Algorithms; Chlorpheniramine; Dextromethorphan; Drug Combinations; Drug O

2007