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propofol and Schizophrenia

propofol has been researched along with Schizophrenia in 18 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"While propofol is known to shorten seizures during electroconvulsive therapy, in our previous study on patients with schizophrenia, there was no need for more frequent restimulations when using propofol compared with etomidate."9.12Comparison of propofol and etomidate regarding impact on seizure threshold during electroconvulsive therapy in patients with schizophrenia. ( Gábor, G; Judit, T; Zsolt, I, 2007)
"We studied the changes in the bispectral index (BIS) of 22 patients during electroconvulsive therapy (ECT) under propofol and succinylcholine anesthesia."7.72[Bispectral index monitoring during anesthesia with propofol for electroconvulsive therapy]. ( Kazama, T; Nakai, T; Satoh, T; Umeda, E, 2004)
"Propofol was found to reduce seizure duration to a significantly greater extent than etomidate."6.71Etomidate versus propofol for electroconvulsive therapy in patients with schizophrenia. ( Gazdag, G; Iványi, Z; Kocsis, N; Tolna, J, 2004)
"Malignant catatonia (MC) is a movement disorder syndrome characterized by immobility, rigidity, and consciousness disorders that develops in association with mental and physical diseases."5.62Successful diagnosis and treatment of pulmonary aspergillosis-related malignant catatonia using propofol and quetiapine: A case report. ( Aisaka, W; Narimatsu, E; Nomura, K; Okamoto, H; Sakawaki, E; Sakawaki, S; Takeyama, Y; Uemura, S; Yamaoka, A, 2021)
"Postictal delirium is an acute confusional state occurring during the immediate postictal phase in patients receiving electroconvulsive therapy that is characterized by motor agitation, disorientation, clouded consciousness, repetitive stereotyped movements, and poor response to commands."5.32Propofol in the management of postictal delirium with clozapine-electroconvulsive therapy combination. ( Bouckaert, F; Fernandez, I; Hagon, A; Hagon, B; Peuskens, J; Sienaert, P, 2004)
"While propofol is known to shorten seizures during electroconvulsive therapy, in our previous study on patients with schizophrenia, there was no need for more frequent restimulations when using propofol compared with etomidate."5.12Comparison of propofol and etomidate regarding impact on seizure threshold during electroconvulsive therapy in patients with schizophrenia. ( Gábor, G; Judit, T; Zsolt, I, 2007)
"Recorded files of patients from the two clinics were compared in terms of ECT indications, number and duration of seizures, and anesthetic agents used (propofol vs."3.79Comparing ECT data of two different inpatient clinics: propofol or thiopental? ( Bosgelmez, S; Karabulut, U; Kirpinar, I; Tas, HI; Yazici, AB; Yazici, E; Yildiz, M, 2013)
"We studied the changes in the bispectral index (BIS) of 22 patients during electroconvulsive therapy (ECT) under propofol and succinylcholine anesthesia."3.72[Bispectral index monitoring during anesthesia with propofol for electroconvulsive therapy]. ( Kazama, T; Nakai, T; Satoh, T; Umeda, E, 2004)
"Propofol was found to reduce seizure duration to a significantly greater extent than etomidate."2.71Etomidate versus propofol for electroconvulsive therapy in patients with schizophrenia. ( Gazdag, G; Iványi, Z; Kocsis, N; Tolna, J, 2004)
"With methohexital, there was a clear postictal increase of mean blood pressure from 126/78 mm Hg to 161/102 mm Hg, whereas there was no increase with propofol (p = 0."2.69Propofol and methohexital as anesthetic agents for electroconvulsive therapy (ECT): a comparison of seizure-quality measures and vital signs. ( Geretsegger, C; Kartnig, C; Rochowanski, E; Unterrainer, AF, 1998)
"Malignant catatonia (MC) is a movement disorder syndrome characterized by immobility, rigidity, and consciousness disorders that develops in association with mental and physical diseases."1.62Successful diagnosis and treatment of pulmonary aspergillosis-related malignant catatonia using propofol and quetiapine: A case report. ( Aisaka, W; Narimatsu, E; Nomura, K; Okamoto, H; Sakawaki, E; Sakawaki, S; Takeyama, Y; Uemura, S; Yamaoka, A, 2021)
"Although mean motor seizure durations were significantly longer in groups R1 and R2 than in group P (P < 0."1.37Effect of divided supplementation of remifentanil on seizure duration and hemodynamic responses during electroconvulsive therapy under propofol anesthesia. ( Higuchi, M; Kawagishi, T; Nishikawa, K; Shimodate, Y; Yamakage, M, 2011)
"The induction of a seizure is a core event in successful ECT."1.33Remifentanil supplementation of propofol during electroconvulsive therapy: effect on seizure duration and cardiovascular stability. ( Amiaz, R; Aronov, S; Etchin, A; Grunhaus, L; Vishne, T, 2005)
"Postictal delirium is an acute confusional state occurring during the immediate postictal phase in patients receiving electroconvulsive therapy that is characterized by motor agitation, disorientation, clouded consciousness, repetitive stereotyped movements, and poor response to commands."1.32Propofol in the management of postictal delirium with clozapine-electroconvulsive therapy combination. ( Bouckaert, F; Fernandez, I; Hagon, A; Hagon, B; Peuskens, J; Sienaert, P, 2004)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (22.22)18.2507
2000's9 (50.00)29.6817
2010's4 (22.22)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Nomura, K1
Sakawaki, S1
Sakawaki, E1
Yamaoka, A1
Aisaka, W1
Okamoto, H1
Takeyama, Y1
Uemura, S1
Narimatsu, E1
Wojdacz, R1
Święcicki, Ł1
Antosik-Wójcińska, A1
Yazici, E1
Bosgelmez, S1
Tas, HI1
Karabulut, U1
Yazici, AB1
Yildiz, M1
Kirpinar, I1
Kikuchi, A1
Yasui-Furukori, N1
Fujii, A1
Katagai, H2
Kaneko, S1
Nishikawa, K1
Higuchi, M1
Kawagishi, T1
Shimodate, Y1
Yamakage, M1
Wang, N1
Wang, XH1
Lu, J1
Zhang, JY1
Kudoh, A2
Takase, H1
Takazawa, T1
Umeda, E1
Nakai, T1
Satoh, T1
Kazama, T1
Gazdag, G2
Kocsis, N1
Tolna, J2
Iványi, Z2
Sienaert, P1
Bouckaert, F1
Fernandez, I1
Hagon, A1
Hagon, B1
Peuskens, J1
Vishne, T1
Aronov, S1
Amiaz, R1
Etchin, A1
Grunhaus, L1
Gábor, G1
Judit, T1
Zsolt, I1
Sakaguchi, H1
Taguchi, H1
Ushijima, K1
Geretsegger, C1
Rochowanski, E1
Kartnig, C1
Unterrainer, AF1
Tanabe, T1
Sakai, T1
Mi, WD1
Matsuki, A1
Ishihara, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Inonu University, Turgut Ozal Medical Center, Department of Anesthesiology and Reanimation Malatya[NCT02271555]Phase 458 participants (Anticipated)Interventional2014-10-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for propofol and Schizophrenia

ArticleYear
Comparison of the effect of intravenous anesthetics used for anesthesia during electroconvulsive therapy on the hemodynamic safety and the course of ECT.
    Psychiatria polska, 2017, Dec-30, Volume: 51, Issue:6

    Topics: Anesthetics; Anesthetics, Intravenous; Autonomic Nervous System; Bipolar Disorder; Depressive Disord

2017
[Applicability of intravenous anesthesia--special reference to propofol and ketamine].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48 Suppl

    Topics: Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenou

1999

Trials

5 trials available for propofol and Schizophrenia

ArticleYear
The effect of repeated etomidate anesthesia on adrenocortical function during a course of electroconvulsive therapy.
    The journal of ECT, 2011, Volume: 27, Issue:4

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Anesthetics, Intravenous; Electroconvulsive Ther

2011
Effect of preoperative discontinuation of antipsychotics in schizophrenic patients on outcome during and after anaesthesia.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:5

    Topics: Adult; Analysis of Variance; Anesthesia; Anesthesia Recovery Period; Anesthetics, Intravenous; Antip

2004
Etomidate versus propofol for electroconvulsive therapy in patients with schizophrenia.
    The journal of ECT, 2004, Volume: 20, Issue:4

    Topics: Adult; Anesthetics, Intravenous; Cross-Over Studies; Electroconvulsive Therapy; Etomidate; Female; H

2004
Comparison of propofol and etomidate regarding impact on seizure threshold during electroconvulsive therapy in patients with schizophrenia.
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2007, Volume: 9, Issue:3

    Topics: Adult; Anesthetics, Intravenous; Electroconvulsive Therapy; Electroencephalography; Electromyography

2007
Propofol and methohexital as anesthetic agents for electroconvulsive therapy (ECT): a comparison of seizure-quality measures and vital signs.
    The journal of ECT, 1998, Volume: 14, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Carbon Dioxide; Cross-Over

1998

Other Studies

11 other studies available for propofol and Schizophrenia

ArticleYear
Successful diagnosis and treatment of pulmonary aspergillosis-related malignant catatonia using propofol and quetiapine: A case report.
    Medicine, 2021, May-14, Volume: 100, Issue:19

    Topics: Catatonia; Diagnosis, Differential; Female; Humans; Hypnotics and Sedatives; Middle Aged; Neurolepti

2021
Comparing ECT data of two different inpatient clinics: propofol or thiopental?
    International journal of psychiatry in clinical practice, 2013, Volume: 17, Issue:4

    Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Bipolar Disorder; Bra

2013
Identification of predictors of post-ictal delirium after electroconvulsive therapy.
    Psychiatry and clinical neurosciences, 2009, Volume: 63, Issue:2

    Topics: Adult; Anesthesia, General; Catatonia; Delirium; Depressive Disorder, Major; Electroconvulsive Thera

2009
Effect of divided supplementation of remifentanil on seizure duration and hemodynamic responses during electroconvulsive therapy under propofol anesthesia.
    Journal of anesthesia, 2011, Volume: 25, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Depressive Disorder, Major; Dose-Res

2011
Hypnosis first, then dissociation.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:3

    Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Delirium; Hallucinations; Humans; Hypnosis; Ket

2003
[Bispectral index monitoring during anesthesia with propofol for electroconvulsive therapy].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:7

    Topics: Adult; Anesthesia; Anesthesia Recovery Period; Consciousness; Depression; Electroconvulsive Therapy;

2004
Propofol in the management of postictal delirium with clozapine-electroconvulsive therapy combination.
    The journal of ECT, 2004, Volume: 20, Issue:4

    Topics: Adult; Anesthetics, Intravenous; Antipsychotic Agents; Clozapine; Combined Modality Therapy; Deliriu

2004
Remifentanil supplementation of propofol during electroconvulsive therapy: effect on seizure duration and cardiovascular stability.
    The journal of ECT, 2005, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Depressive Disorder, Major; Electroconvuls

2005
Impact of propofol and etomidate on seizure activity during electroconvulsive therapy in patients with schizophrenia.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:1

    Topics: Anesthetics, Intravenous; Electroencephalography; Electromyography; Etomidate; Humans; Propofol; Sch

2007
[Propofol anesthesia for a schizophrenic patient].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:8

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Humans; Male; Perioperative Care; Propofol; Ps

1997
[Electroconvulsive therapy decreased bispectral index--a case report].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:9

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Electroconvulsive Therapy; Electroencephal

1998