propofol has been researched along with Rhabdomyolysis in 61 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This small-size pilot study may suggest that propofol-based anesthesia is not related to increased incidence of rhabdomyolysis in morbidly obese patients undergoing short, uncomplicated bariatric surgery." | 9.20 | Comparison of Rhabdomyolysis Markers in Patients Undergoing Bariatric Surgery with Propofol and Inhalation-based Anesthesia. ( Katz, YS; Lehavi, A; Mahajna, A; Sandler, O; Weissman, A, 2015) |
| "To assess safety and efficacy of propofol and thiopental for refractory status epilepticus (RSE) in children, the authors reviewed 34 episodes of RSE." | 9.11 | Propofol and thiopental for refractory status epilepticus in children. ( Blussé van Oud-Alblas, HJ; Braun, KP; Malingré, M; van Gestel, JP; van Nieuwenhuizen, O; Ververs, FF, 2005) |
| "This anesthetic drug may cause a rare condition named propofol infusion syndrome, characterized by unexplained lactic acidosis, lipemia, rhabdomyolysis, cardiovascular collapse and Brugada-like electrocardiographic pattern or Brugada electrocardiographic phenocopy changes following high-dose propofol infusion over prolonged periods of time." | 8.86 | Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. ( Dubner, S; Ferreira, C; Filho, CF; Riera, AR; Schapachnik, E; Uchida, AH, 2010) |
| " Keywords were propofol, propofol infusion syndrome (PRIS), rhabdomyolysis, heart failure, arrhythmias, metabolic acidosis, brain injury, sedation, intensive care." | 8.86 | [Propofol infusion syndrome]. ( Greff, B; Laquay, N; Meyer, P; Orliaguet, G; Prieur, S, 2010) |
| "Propofol infusion syndrome (PRIS) is defined as acute bradycardia progressing to asystole combined with lipemic plasma, fatty liver enlargement, metabolic acidosis with negative base excess >10 mmol l(-1), rhabdomyolysis or myoglobinuria associated with propofol infusion." | 8.85 | Propofol infusion syndrome: update of clinical manifestation and pathophysiology. ( Bein, B; Fudickar, A, 2009) |
| "This is the first case description of rhabdomyolysis and myoglobinuria following a single dose of injectable propofol." | 8.31 | Rhabdomyolysis and myoglobinuria following single induction dose of propofol in a dog. ( Cervone, M; Nectoux, A; Pouzot-Nevoret, C, 2023) |
| "All patients on the KD who underwent anesthesia with propofol between 2012 and 2022 were reviewed." | 8.31 | Propofol for Anesthesia in Pediatric Patients With Epilepsy on the Ketogenic Diet: A Single-Center Experience. ( Bui, PH; Diaz-Medina, G; Handoko, M; Katyayan, A; Ng, AS, 2023) |
| "Propofol infusion syndrome (PRIS), a rare complication of propofol sedation, is associated with high mortality." | 7.81 | Therapeutic plasma exchange as treatment for propofol infusion syndrome. ( Levin, PD; Levin, V; Rund, D; Sprung, CL; Weissman, C, 2015) |
| "To report a case of propofol-induced rhabdomyolysis." | 7.81 | Propofol-induced rhabdomyolysis: a case report. ( Feng, X; Huang, WQ; Niu, LJ; Xiao, LC; Yang, XY; Zhou, X; Zhou, ZB, 2015) |
| "Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death." | 7.80 | Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol. ( Clement, LP; Croce, MA; Fabian, TC; Fischer, PE; Lee, M; Magnotti, LJ; Schroeppel, TJ; Sharpe, JP, 2014) |
| "To address the issue of propofol-related infusion syndrome and its management." | 7.79 | Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients. ( Imam, TH, 2013) |
| "A 33-year-old previously healthy woman was admitted after a drug overdose combining colchicine, atorvastatin, ibuprofen, diclofenac, and furosemide." | 7.76 | Multiple organ failure after an overdose of less than 0.4 mg/kg of colchicine: role of coingestants and drugs during intensive care management. ( Bonbled, F; Hantson, P; Huberlant, V; Montiel, V; Vincent, MF, 2010) |
| "Propofol is increasingly used for the treatment of status epilepticus due to the ease of use and tolerability, even if safety data from randomized clinical trials are lacking." | 7.74 | Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus. ( Harris, BT; Jobst, BC; Zarovnaya, EL, 2007) |
| "The occurrence of metabolic acidosis, rhabdomyolysis, hyperkalemia, and sudden cardiac death after long-term, high-dose propofol infusion has been referred to as propofol infusion syndrome (PRIS)." | 7.73 | Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome. ( Antzelevitch, C; Brugada, R; Cremer, OL; Crijns, HJ; Delhaas, T; Di Diego, JM; Kalkman, CJ; Oliva, A; Prinzen, FW; Rodriguez, LM; Timmermans, C; Vernooy, K; Volders, PG, 2006) |
| "The propofol infusion syndrome is a rare but potentially lethal complication resulting from a prolonged continuous administration of propofol." | 7.73 | [Propofol infusion syndrome]. ( Jost, R; Likar, R; Oher, M; Pointner, I; Schalk, HV; Trampitsch, E, 2006) |
| "Propofol is used for the treatment of refractory status epilepticus." | 7.72 | Fatal propofol infusion syndrome in association with ketogenic diet. ( Baumeister, FA; Eberhardt, J; Holthausen, H; Kunkel, J; Liebhaber, GM; Oberhoffer, R; Peters, J, 2004) |
| "The authors present the hospital course of a 13-year-old girl with a closed head injury who received a prolonged infusion of propofol for sedation and, subsequently, died as a result of severe metabolic acidosis, rhabdomyolysis, and cardiovascular collapse." | 7.71 | Metabolic acidosis, rhabdomyolysis, and cardiovascular collapse after prolonged propofol infusion. ( Bauman, LA; Cannon, ML; Glazier, SS, 2001) |
| "Propofol, a central-acting sedative agent, has been implicated in the development of rhabdomyolysis in children." | 7.70 | Propofol-associated rhabdomyolysis with cardiac involvement in adults: chemical and anatomic findings. ( Apple, FS; Crosson, JT; Johari, VP; Smith, SA; Stelow, EB, 2000) |
| "Propofol is a short-acting intravenous anesthetic agent widely used for sedation in anesthesia and intensive care." | 6.44 | The propofol infusion 'syndrome' in intensive care unit: from pathophysiology to prophylaxis and treatment. ( Dragoumanis, C; Papaioannou, V; Pneumatikos, I; Theodorou, V, 2008) |
| "Propofol has gained popularity for its rapid onset and rapid recovery even after prolonged use, and for the neuroprotection conferred." | 6.44 | Propofol infusion syndrome: an overview of a perplexing disease. ( Fodale, V; La Monaca, E, 2008) |
| "Concerned patients present with Leigh syndrome symptoms or a Leigh-like syndrome." | 5.72 | A Case of ECHS1 Deficiency with Severe Encephalopathy and Status Epilepticus after a Propofol Sedation: Case Report. ( Lutz, S; Paraschaki, G; Preusse, M, 2022) |
| "Propofol infusion syndrome is a rare but frequently fatal complication in critically ill children who are given prolonged high-dose infusions of the drug." | 5.34 | Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury. ( Coritsidis, G; Rehman, Z; Sabsovich, I; Yunen, J, 2007) |
| "She developed multiple organ failure with rhabdomyolysis and died." | 5.33 | A case of suspected non-neurosurgical adult fatal propofol infusion syndrome. ( Eriksen, J; Povey, HM, 2006) |
| "This small-size pilot study may suggest that propofol-based anesthesia is not related to increased incidence of rhabdomyolysis in morbidly obese patients undergoing short, uncomplicated bariatric surgery." | 5.20 | Comparison of Rhabdomyolysis Markers in Patients Undergoing Bariatric Surgery with Propofol and Inhalation-based Anesthesia. ( Katz, YS; Lehavi, A; Mahajna, A; Sandler, O; Weissman, A, 2015) |
| "To assess safety and efficacy of propofol and thiopental for refractory status epilepticus (RSE) in children, the authors reviewed 34 episodes of RSE." | 5.11 | Propofol and thiopental for refractory status epilepticus in children. ( Blussé van Oud-Alblas, HJ; Braun, KP; Malingré, M; van Gestel, JP; van Nieuwenhuizen, O; Ververs, FF, 2005) |
| "This anesthetic drug may cause a rare condition named propofol infusion syndrome, characterized by unexplained lactic acidosis, lipemia, rhabdomyolysis, cardiovascular collapse and Brugada-like electrocardiographic pattern or Brugada electrocardiographic phenocopy changes following high-dose propofol infusion over prolonged periods of time." | 4.86 | Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. ( Dubner, S; Ferreira, C; Filho, CF; Riera, AR; Schapachnik, E; Uchida, AH, 2010) |
| " Keywords were propofol, propofol infusion syndrome (PRIS), rhabdomyolysis, heart failure, arrhythmias, metabolic acidosis, brain injury, sedation, intensive care." | 4.86 | [Propofol infusion syndrome]. ( Greff, B; Laquay, N; Meyer, P; Orliaguet, G; Prieur, S, 2010) |
| "Propofol infusion syndrome (PRIS) is defined as acute bradycardia progressing to asystole combined with lipemic plasma, fatty liver enlargement, metabolic acidosis with negative base excess >10 mmol l(-1), rhabdomyolysis or myoglobinuria associated with propofol infusion." | 4.85 | Propofol infusion syndrome: update of clinical manifestation and pathophysiology. ( Bein, B; Fudickar, A, 2009) |
| "All patients on the KD who underwent anesthesia with propofol between 2012 and 2022 were reviewed." | 4.31 | Propofol for Anesthesia in Pediatric Patients With Epilepsy on the Ketogenic Diet: A Single-Center Experience. ( Bui, PH; Diaz-Medina, G; Handoko, M; Katyayan, A; Ng, AS, 2023) |
| "This is the first case description of rhabdomyolysis and myoglobinuria following a single dose of injectable propofol." | 4.31 | Rhabdomyolysis and myoglobinuria following single induction dose of propofol in a dog. ( Cervone, M; Nectoux, A; Pouzot-Nevoret, C, 2023) |
| "Propofol infusion syndrome (PRIS), a rare complication of propofol sedation, is associated with high mortality." | 3.81 | Therapeutic plasma exchange as treatment for propofol infusion syndrome. ( Levin, PD; Levin, V; Rund, D; Sprung, CL; Weissman, C, 2015) |
| "Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death." | 3.80 | Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol. ( Clement, LP; Croce, MA; Fabian, TC; Fischer, PE; Lee, M; Magnotti, LJ; Schroeppel, TJ; Sharpe, JP, 2014) |
| "To address the issue of propofol-related infusion syndrome and its management." | 3.79 | Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients. ( Imam, TH, 2013) |
| "A 33-year-old previously healthy woman was admitted after a drug overdose combining colchicine, atorvastatin, ibuprofen, diclofenac, and furosemide." | 3.76 | Multiple organ failure after an overdose of less than 0.4 mg/kg of colchicine: role of coingestants and drugs during intensive care management. ( Bonbled, F; Hantson, P; Huberlant, V; Montiel, V; Vincent, MF, 2010) |
| "Propofol is increasingly used for the treatment of status epilepticus due to the ease of use and tolerability, even if safety data from randomized clinical trials are lacking." | 3.74 | Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus. ( Harris, BT; Jobst, BC; Zarovnaya, EL, 2007) |
| "Propofol infusion syndrome, characterised by cardiovascular collapse, metabolic acidosis, hepatomegaly, renal failure and rhabdomyolysis, is a rare and often fatal syndrome seen in critically ill children undergoing long-term propofol sedation." | 3.73 | [Propofol infusion syndrome in children]. ( Hansen, TG, 2005) |
| "High-dose propofol infusion for sedation of patients in the intensive care unit can result in rhabdomyolysis, acute renal failure, metabolic acidosis, hyperkalemia, ventricular arrhythmia, hyperthermia, and death." | 3.73 | A lethal complication of propofol. ( Chavez, VM; Haake, RJ; Hayat, SA; Suen, HC, 2006) |
| "The occurrence of metabolic acidosis, rhabdomyolysis, hyperkalemia, and sudden cardiac death after long-term, high-dose propofol infusion has been referred to as propofol infusion syndrome (PRIS)." | 3.73 | Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome. ( Antzelevitch, C; Brugada, R; Cremer, OL; Crijns, HJ; Delhaas, T; Di Diego, JM; Kalkman, CJ; Oliva, A; Prinzen, FW; Rodriguez, LM; Timmermans, C; Vernooy, K; Volders, PG, 2006) |
| "The propofol infusion syndrome is a rare but potentially lethal complication resulting from a prolonged continuous administration of propofol." | 3.73 | [Propofol infusion syndrome]. ( Jost, R; Likar, R; Oher, M; Pointner, I; Schalk, HV; Trampitsch, E, 2006) |
| " We present a detailed description of the case and also discuss the role of propofol and rhabdomyolysis." | 3.72 | A fatal case of malignant hyperthermia complicated by generalized compartment syndrome and rhabdomyolysis. ( Green, G, 2003) |
| "Propofol is used for the treatment of refractory status epilepticus." | 3.72 | Fatal propofol infusion syndrome in association with ketogenic diet. ( Baumeister, FA; Eberhardt, J; Holthausen, H; Kunkel, J; Liebhaber, GM; Oberhoffer, R; Peters, J, 2004) |
| "The authors present the hospital course of a 13-year-old girl with a closed head injury who received a prolonged infusion of propofol for sedation and, subsequently, died as a result of severe metabolic acidosis, rhabdomyolysis, and cardiovascular collapse." | 3.71 | Metabolic acidosis, rhabdomyolysis, and cardiovascular collapse after prolonged propofol infusion. ( Bauman, LA; Cannon, ML; Glazier, SS, 2001) |
| "Propofol, a central-acting sedative agent, has been implicated in the development of rhabdomyolysis in children." | 3.70 | Propofol-associated rhabdomyolysis with cardiac involvement in adults: chemical and anatomic findings. ( Apple, FS; Crosson, JT; Johari, VP; Smith, SA; Stelow, EB, 2000) |
| "Rhabdomyolysis is a clinical condition of potential life threatening destruction of skeletal muscle caused by diverse mechanisms including drugs and toxins." | 2.48 | Drug induced rhabdomyolysis. ( Hohenegger, M, 2012) |
| "Propofol is a potent intravenous anesthetic agent that rapidly induces sedation and unconsciousness." | 2.47 | Clinical effects and lethal and forensic aspects of propofol. ( Levy, RJ, 2011) |
| "Propofol has gained popularity for its rapid onset and rapid recovery even after prolonged use, and for the neuroprotection conferred." | 2.44 | Propofol infusion syndrome: an overview of a perplexing disease. ( Fodale, V; La Monaca, E, 2008) |
| "Propofol is a short-acting intravenous anesthetic agent widely used for sedation in anesthesia and intensive care." | 2.44 | The propofol infusion 'syndrome' in intensive care unit: from pathophysiology to prophylaxis and treatment. ( Dragoumanis, C; Papaioannou, V; Pneumatikos, I; Theodorou, V, 2008) |
| "Early trauma patients also showed improved survival following war injuries when dialyzed prophylactically." | 2.43 | Continuous renal replacement therapy in patients following traumatic injury. ( McCourt, T; McCunn, M; McQuillan, K; Reuter, J; Reynolds, HN; Stein, D, 2006) |
| "Concerned patients present with Leigh syndrome symptoms or a Leigh-like syndrome." | 1.72 | A Case of ECHS1 Deficiency with Severe Encephalopathy and Status Epilepticus after a Propofol Sedation: Case Report. ( Lutz, S; Paraschaki, G; Preusse, M, 2022) |
| "The diagnosis of malignant hyperthermia (MH) susceptibility could be confirmed in the patient 4 months after the acute event by the in vitro contracture test and detection of the MH causative mutation p." | 1.48 | [Abortive course of malignant hyperthermia following preclinical induction of general anesthesia using succinylcholine]. ( Helf, D; Johannsen, S; Markus, CK; Schneiderbanger, D; Schuster, F, 2018) |
| "We present 2 cases of fulminant malignant hyperthermia (MH), complicated with massive rhabdomyolysis." | 1.39 | Continuous veno-venous hemofiltration for massive rhabdomyolysis after malignant hyperthermia: report of 2 cases. ( Fang, S; Jiang, H; Xu, H; Zhu, Y, 2013) |
| "Patients with Duchenne muscular dystrophy are at increased risk of some anaesthesia-related hazards such as rhabdomyolysis, fever and hyperkalaemia." | 1.38 | Anaesthetic management in patients with Duchenne muscular dystrophy undergoing orthopaedic surgery: a review of 232 cases. ( Forst, J; Huber, H; Mueller, C; Muenster, T; Schmitt, HJ, 2012) |
| "We reviewed all patients with severe head trauma admitted to our Neuro-Intensive Care Unit over a 4-year period for use of propofol and vasopressors." | 1.35 | Vasopressors and propofol infusion syndrome in severe head trauma. ( Sinson, G; Smith, H; Varelas, P, 2009) |
| "Propofol infusion syndrome is a rare but frequently fatal complication in critically ill children who are given prolonged high-dose infusions of the drug." | 1.34 | Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury. ( Coritsidis, G; Rehman, Z; Sabsovich, I; Yunen, J, 2007) |
| "She developed multiple organ failure with rhabdomyolysis and died." | 1.33 | A case of suspected non-neurosurgical adult fatal propofol infusion syndrome. ( Eriksen, J; Povey, HM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (4.92) | 18.2507 |
| 2000's | 34 (55.74) | 29.6817 |
| 2010's | 20 (32.79) | 24.3611 |
| 2020's | 4 (6.56) | 2.80 |
| Authors | Studies |
|---|---|
| Preusse, M | 1 |
| Paraschaki, G | 1 |
| Lutz, S | 1 |
| Cervone, M | 1 |
| Nectoux, A | 1 |
| Pouzot-Nevoret, C | 1 |
| Bui, PH | 1 |
| Handoko, M | 1 |
| Diaz-Medina, G | 1 |
| Ng, AS | 1 |
| Katyayan, A | 1 |
| Kaur, B | 1 |
| Rattalino, M | 1 |
| Helf, D | 1 |
| Schneiderbanger, D | 1 |
| Markus, CK | 1 |
| Johannsen, S | 1 |
| Schuster, F | 1 |
| Fang, S | 1 |
| Xu, H | 1 |
| Zhu, Y | 1 |
| Jiang, H | 1 |
| Imam, TH | 1 |
| Schroeppel, TJ | 1 |
| Fabian, TC | 1 |
| Clement, LP | 1 |
| Fischer, PE | 1 |
| Magnotti, LJ | 1 |
| Sharpe, JP | 1 |
| Lee, M | 1 |
| Croce, MA | 1 |
| Savard, M | 3 |
| Dupré, N | 1 |
| Turgeon, AF | 3 |
| Desbiens, R | 1 |
| Langevin, S | 1 |
| Brunet, D | 1 |
| Parness, J | 1 |
| Levin, PD | 1 |
| Levin, V | 1 |
| Weissman, C | 1 |
| Sprung, CL | 1 |
| Rund, D | 1 |
| Lehavi, A | 1 |
| Sandler, O | 1 |
| Mahajna, A | 1 |
| Weissman, A | 1 |
| Katz, YS | 1 |
| Zhou, ZB | 1 |
| Yang, XY | 1 |
| Zhou, X | 1 |
| Niu, LJ | 1 |
| Xiao, LC | 1 |
| Huang, WQ | 1 |
| Feng, X | 1 |
| Schifano, F | 1 |
| Papanti, GD | 1 |
| Orsolini, L | 1 |
| Corkery, JM | 1 |
| Zaccheo, MM | 1 |
| Bucher, DH | 1 |
| Shimony, A | 1 |
| Almog, Y | 1 |
| Zahger, D | 1 |
| Papaioannou, V | 1 |
| Dragoumanis, C | 1 |
| Theodorou, V | 1 |
| Pneumatikos, I | 1 |
| Smith, H | 1 |
| Sinson, G | 1 |
| Varelas, P | 1 |
| Fudickar, A | 1 |
| Bein, B | 1 |
| Laquay, N | 1 |
| Prieur, S | 1 |
| Greff, B | 1 |
| Meyer, P | 1 |
| Orliaguet, G | 1 |
| Riera, AR | 1 |
| Uchida, AH | 1 |
| Schapachnik, E | 1 |
| Dubner, S | 1 |
| Filho, CF | 1 |
| Ferreira, C | 1 |
| Levy, RJ | 1 |
| Montiel, V | 1 |
| Huberlant, V | 1 |
| Vincent, MF | 1 |
| Bonbled, F | 1 |
| Hantson, P | 1 |
| Amrein, S | 1 |
| Amrein, K | 1 |
| Amegah-Sakotnik, A | 1 |
| Reist, U | 1 |
| Ensner, R | 1 |
| Testerman, GM | 1 |
| Chow, TT | 1 |
| Easparam, S | 1 |
| Annecke, T | 1 |
| Conzen, P | 1 |
| Ney, L | 1 |
| Hohenegger, M | 1 |
| Muenster, T | 1 |
| Mueller, C | 1 |
| Forst, J | 1 |
| Huber, H | 1 |
| Schmitt, HJ | 1 |
| Cassidy, JV | 1 |
| Bolton, DT | 1 |
| Haynes, SR | 1 |
| Smith, JH | 1 |
| Crawford, MW | 1 |
| Dodgson, BG | 1 |
| Holtby, HH | 1 |
| Roy, WL | 1 |
| Green, G | 1 |
| Cray, SH | 1 |
| Pettifer, RJ | 1 |
| Baumeister, FA | 1 |
| Oberhoffer, R | 1 |
| Liebhaber, GM | 1 |
| Kunkel, J | 1 |
| Eberhardt, J | 1 |
| Holthausen, H | 1 |
| Peters, J | 1 |
| Betrosian, AP | 1 |
| Papanikoleou, M | 1 |
| Frantzeskaki, F | 1 |
| Diakalis, C | 1 |
| Georgiadis, G | 1 |
| Augoustides, JG | 1 |
| Culp, KE | 1 |
| Ochroch, AE | 1 |
| Milas, BL | 1 |
| van Gestel, JP | 1 |
| Blussé van Oud-Alblas, HJ | 1 |
| Malingré, M | 1 |
| Ververs, FF | 1 |
| Braun, KP | 1 |
| van Nieuwenhuizen, O | 1 |
| Hansen, TG | 1 |
| Suen, HC | 1 |
| Haake, RJ | 1 |
| Chavez, VM | 1 |
| Hayat, SA | 1 |
| Wessel, N | 1 |
| Schirdewan, A | 1 |
| Vernooy, K | 1 |
| Delhaas, T | 1 |
| Cremer, OL | 1 |
| Di Diego, JM | 1 |
| Oliva, A | 1 |
| Timmermans, C | 1 |
| Volders, PG | 1 |
| Prinzen, FW | 1 |
| Crijns, HJ | 1 |
| Antzelevitch, C | 1 |
| Kalkman, CJ | 1 |
| Rodriguez, LM | 1 |
| Brugada, R | 1 |
| Eriksen, J | 1 |
| Povey, HM | 1 |
| Salengros, JC | 1 |
| Engelman, E | 1 |
| Hermanns, H | 1 |
| Lipfert, P | 1 |
| Ladda, S | 1 |
| Stevens, MF | 1 |
| McCunn, M | 1 |
| Reynolds, HN | 1 |
| Reuter, J | 1 |
| McQuillan, K | 1 |
| McCourt, T | 1 |
| Stein, D | 1 |
| Trampitsch, E | 1 |
| Oher, M | 1 |
| Pointner, I | 1 |
| Likar, R | 1 |
| Jost, R | 1 |
| Schalk, HV | 1 |
| De Waele, JJ | 1 |
| Hoste, E | 1 |
| Sabsovich, I | 1 |
| Rehman, Z | 1 |
| Yunen, J | 1 |
| Coritsidis, G | 1 |
| Zarovnaya, EL | 1 |
| Jobst, BC | 1 |
| Harris, BT | 1 |
| Francis, L | 1 |
| Bonilla, E | 1 |
| Soforo, E | 1 |
| Neupane, H | 1 |
| Nakhla, H | 1 |
| Fuller, C | 1 |
| Perl, A | 1 |
| Phadke, A | 1 |
| Broadman, LM | 1 |
| Brandom, BW | 1 |
| Ozolek, J | 1 |
| Davis, PJ | 1 |
| Fodale, V | 1 |
| La Monaca, E | 1 |
| van Straaten, EA | 1 |
| Hendriks, JJ | 1 |
| Ramsey, G | 1 |
| Vos, GD | 1 |
| Pollock, AN | 1 |
| McKenzie, AJ | 1 |
| Hodges, M | 1 |
| Snoeck, MM | 1 |
| Hanna, JP | 1 |
| Ramundo, ML | 1 |
| Stelow, EB | 1 |
| Johari, VP | 1 |
| Smith, SA | 1 |
| Crosson, JT | 1 |
| Apple, FS | 1 |
| Markovitz, BP | 1 |
| Feuer, P | 1 |
| Cox, P | 1 |
| Myburgh, JA | 1 |
| Upton, RN | 1 |
| Cannon, ML | 1 |
| Glazier, SS | 1 |
| Bauman, LA | 1 |
| Abrahams, JM | 1 |
| Reiter, GT | 1 |
| Acker, MA | 1 |
| Sinson, GP | 1 |
| Friedman, JA | 1 |
| Manno, E | 1 |
| Fulgham, JR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia[NCT04235894] | 124 participants (Actual) | Observational | 2016-09-07 | Completed | |||
| Keto-diet for Intubated Critical Care COVID-19 (KICC-COVID19)[NCT04358835] | 0 participants (Actual) | Interventional | 2020-09-01 | Withdrawn (stopped due to Study did not begin enrollment, multiple competing studies at same institution) | |||
| Norwegian Intensive Care Unit Dalteparin Effect Study[NCT01721928] | 70 participants (Actual) | Observational | 2012-12-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for propofol and Rhabdomyolysis
| Article | Year |
|---|---|
Novel psychoactive substances: the pharmacology of stimulants and hallucinogens.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Central Nervous System Stimulants; Fever; Hallucinog | 2016 |
Propofol infusion syndrome: a rare complication with potentially fatal results.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Critical Care; | 2008 |
The propofol infusion 'syndrome' in intensive care unit: from pathophysiology to prophylaxis and treatment.
Topics: Acidosis; Adult; Anesthetics, Intravenous; Cardiovascular Diseases; Child; Heart; Humans; Hyperkalem | 2008 |
Propofol infusion syndrome: update of clinical manifestation and pathophysiology.
Topics: Acidosis; Acute Disease; Adult; Age Factors; Anesthetics, Intravenous; Animals; Bradycardia; Brain I | 2009 |
[Propofol infusion syndrome].
Topics: Acidosis; Arrhythmias, Cardiac; Heart Failure; Humans; Hypnotics and Sedatives; Infusions, Intraveno | 2010 |
Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy.
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Animals; Brugada Syndrome; Electrocardiography; Heart Co | 2010 |
Clinical effects and lethal and forensic aspects of propofol.
Topics: Accidents; Acidosis; Acute Kidney Injury; Bacteremia; Bradycardia; Drug Overdose; Dyslipidemias; For | 2011 |
Drug induced rhabdomyolysis.
Topics: Animals; Enzyme Inhibitors; Heart; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Pr | 2012 |
Continuous renal replacement therapy in patients following traumatic injury.
Topics: Acute Kidney Injury; Anticoagulants; Critical Care; Humans; Hypnotics and Sedatives; Kidneys, Artifi | 2006 |
Propofol infusion syndrome: an overview of a perplexing disease.
Topics: Acidosis; Anesthetics, Intravenous; Arrhythmias, Cardiac; Heart Failure; Hepatomegaly; Humans; Hypno | 2008 |
Rhabdomyolysis and hypoxia associated with prolonged propofol infusion in children.
Topics: Adolescent; Child; Critical Care; Humans; Hypnotics and Sedatives; Hypoxia; Male; Propofol; Respirat | 1998 |
2 trials available for propofol and Rhabdomyolysis
| Article | Year |
|---|---|
Comparison of Rhabdomyolysis Markers in Patients Undergoing Bariatric Surgery with Propofol and Inhalation-based Anesthesia.
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Intravenous; Bariatric Surgery; Biomarkers; Female; Gast | 2015 |
Propofol and thiopental for refractory status epilepticus in children.
Topics: Anticonvulsants; Child; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Sc | 2005 |
48 other studies available for propofol and Rhabdomyolysis
| Article | Year |
|---|---|
A Case of ECHS1 Deficiency with Severe Encephalopathy and Status Epilepticus after a Propofol Sedation: Case Report.
Topics: Atrophy; Cardiomyopathies; Enoyl-CoA Hydratase; Humans; Infant; Leigh Disease; Lipid Metabolism, Inb | 2022 |
Rhabdomyolysis and myoglobinuria following single induction dose of propofol in a dog.
Topics: Animals; Diazepam; Dog Diseases; Dogs; Isoflurane; Male; Myoglobinuria; Propofol; Rhabdomyolysis | 2023 |
Propofol for Anesthesia in Pediatric Patients With Epilepsy on the Ketogenic Diet: A Single-Center Experience.
Topics: Acidosis; Anesthesia; Anesthetics; Anesthetics, Intravenous; Child; Diet, Ketogenic; Epilepsy; Human | 2023 |
Target-controlled infusion of Propofol and Remifentanil in a child with recurrent rhabdomyolysis secondary to LPIN1 deficiency.
Topics: Anesthetics, Intravenous; Child; Humans; Infusions, Intravenous; Phosphatidate Phosphatase; Piperidi | 2020 |
[Abortive course of malignant hyperthermia following preclinical induction of general anesthesia using succinylcholine].
Topics: Anesthesia, General; Anesthetics, Intravenous; Dantrolene; Female; Fentanyl; Humans; Malignant Hyper | 2018 |
Continuous veno-venous hemofiltration for massive rhabdomyolysis after malignant hyperthermia: report of 2 cases.
Topics: Acute Kidney Injury; Adolescent; Adult; Anesthesia, Dental; Anesthesia, General; Anesthetics, Intrav | 2013 |
Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients.
Topics: Arrhythmias, Cardiac; Fatal Outcome; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; | 2013 |
Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Cohort Studies | 2014 |
Propofol-related infusion syndrome heralding a mitochondrial disease: case report.
Topics: Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Diagnosis, Differential; Fatal Outcome; Femal | 2013 |
Propofol-related infusion syndrome heralding a mitochondrial disease: case report.
Topics: Arrhythmias, Cardiac; Female; Humans; Mitochondrial Diseases; Propofol; Renal Insufficiency; Rhabdom | 2014 |
Author response.
Topics: Arrhythmias, Cardiac; Female; Humans; Mitochondrial Diseases; Propofol; Renal Insufficiency; Rhabdom | 2014 |
Therapeutic plasma exchange as treatment for propofol infusion syndrome.
Topics: Accidents, Traffic; Acidosis, Lactic; Acute Kidney Injury; Adolescent; Anticonvulsants; Biomarkers; | 2015 |
Propofol-induced rhabdomyolysis: a case report.
Topics: Anesthetics, Intravenous; Female; Humans; Middle Aged; Propofol; Rhabdomyolysis | 2015 |
Propofol infusion syndrome: a rare cause of multi-organ failure in a man with complicated myocardial infarction.
Topics: Anesthetics, Intravenous; Humans; Male; Middle Aged; Multiple Organ Failure; Myocardial Infarction; | 2008 |
Vasopressors and propofol infusion syndrome in severe head trauma.
Topics: Acidosis; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Craniocerebral Trauma; Creatine | 2009 |
Multiple organ failure after an overdose of less than 0.4 mg/kg of colchicine: role of coingestants and drugs during intensive care management.
Topics: Adult; Atorvastatin; Colchicine; Critical Care; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhib | 2010 |
Propofol infusion syndrome--a critical incident report highlighting the danger of reexposure.
Topics: Adult; Arrhythmias, Cardiac; Head Injuries, Closed; Humans; Hypnotics and Sedatives; Hypotension; In | 2011 |
Propofol infusion syndrome: an algorithm for prevention.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2011 |
Propofol-related infusion syndrome induced by "moderate dosage" in a patient with severe head trauma.
Topics: Acidosis; Adult; Anesthetics, Intravenous; Craniocerebral Trauma; Dose-Response Relationship, Drug; | 2012 |
Anaesthetic management in patients with Duchenne muscular dystrophy undergoing orthopaedic surgery: a review of 232 cases.
Topics: Adolescent; Analgesics, Opioid; Anesthesia; Anesthesia, General; Anesthetics; Child; Child, Preschoo | 2012 |
Acute rhabdomyolysis after cardiac transplantation: a diagnostic conundrum.
Topics: Acute Disease; Adolescent; Anesthetics, Intravenous; Creatinine; Cyclosporine; Female; Heart Transpl | 2002 |
Propofol syndrome in children.
Topics: Acidosis; Age Factors; Anesthetics, Intravenous; Child; Conscious Sedation; Critical Illness; Hepato | 2003 |
A fatal case of malignant hyperthermia complicated by generalized compartment syndrome and rhabdomyolysis.
Topics: Adult; Anesthetics, Intravenous; Compartment Syndromes; Dantrolene; Fatal Outcome; Hemorrhage; Human | 2003 |
Sedation in pediatric patients.
Topics: Acidosis; Anesthetics, Intravenous; Bradycardia; Child; Conscious Sedation; Drug Monitoring; Humans; | 2003 |
Fatal propofol infusion syndrome in association with ketogenic diet.
Topics: Acidosis; Anticonvulsants; Child; Diet Therapy; Fatal Outcome; Humans; Infusions, Parenteral; Male; | 2004 |
Myoglobinemia and propofol infusion.
Topics: Adult; Anesthetics, Intravenous; Chlorine; Critical Illness; Humans; Male; Myoglobin; Near Drowning; | 2005 |
Total suppression of cerebral activity by thiopental mimicking propofol infusion syndrome: a fatal common pathway?
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Brain; Craniotomy; Dose-Response Relationship, Dr | 2005 |
[Propofol infusion syndrome in children].
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Child; Hepatomegaly; Huma | 2005 |
A lethal complication of propofol.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Creatine Kinase; Dose-Response Relat | 2006 |
Toward a prediction of sudden death in propofol-related infusion syndrome.
Topics: Acidosis; Acute Kidney Injury; Death, Sudden, Cardiac; Electrocardiography; Humans; Hypnotics and Se | 2006 |
Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Death, Sudden, Cardiac; Electrocardiography; Humans; Hypn | 2006 |
A case of suspected non-neurosurgical adult fatal propofol infusion syndrome.
Topics: Adolescent; Anesthetics, Intravenous; Fatal Outcome; Female; Humans; Hypnotics and Sedatives; Infusi | 2006 |
Myoglobinemia and propofol infusion.
Topics: Anesthetics, Intravenous; Humans; Myoglobin; Propofol; Rhabdomyolysis; Syndrome | 2006 |
Propofol infusion syndrome during anaesthesia for scoliosis surgery in an adolescent with neonatal progeroid syndrome.
Topics: Acidosis; Adolescent; Anesthetics, Intravenous; Arrhythmias, Cardiac; Female; Humans; Progeria; Prop | 2006 |
[Propofol infusion syndrome].
Topics: Acidosis; Acute Kidney Injury; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Arrhythmias, | 2006 |
Propofol infusion syndrome in a patient with sepsis.
Topics: Abdominal Abscess; Acidosis; Adult; Anesthetics, Intravenous; Drainage; Heart Failure; Humans; Hyper | 2006 |
Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Anesthetics, Intravenous; Brain Injuries; Fatal Outcome; | 2007 |
Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus.
Topics: Acidosis; Adult; Age Factors; Anticonvulsants; Cardiac Output, Low; Cardiomyopathies; Fatal Outcome; | 2007 |
Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin.
Topics: Aged; Colchicine; Creatine Kinase; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions | 2008 |
Postoperative hyperthermia, rhabdomyolysis, critical temperature, and death in a former premature infant after his ninth general anesthetic.
Topics: Analgesics, Opioid; Anesthesia, General; Fatal Outcome; Fentanyl; Fever; Humans; Infant; Infant, New | 2007 |
Rhabdomyolysis and pulmonary hypertension in a child, possibly due to long-term high-dose propofol infusion.
Topics: Child, Preschool; Humans; Hypertension, Pulmonary; Hypnotics and Sedatives; Male; Propofol; Respirat | 1996 |
Propofol and malignant hyperthermia susceptibility.
Topics: Acidosis; Adolescent; Adult; Aged; Anesthetics, Intravenous; Arrhythmias, Cardiac; Cause of Death; C | 1997 |
Propofol-associated rhabdomyolysis with cardiac involvement in adults: chemical and anatomic findings.
Topics: Adult; Biomarkers; Cardiomyopathies; Creatine Kinase; Female; Humans; Hypnotics and Sedatives; Kidne | 2000 |
Rare events often happen infrequently: propofol complications revisited.
Topics: Acidosis; Anesthetics, Intravenous; Bradycardia; Child; Humans; Propofol; Rhabdomyolysis; Shock | 2000 |
Propofol use in head-injury patients.
Topics: Acidosis; Adolescent; Adult; Anesthetics, Intravenous; Animals; Cardiac Output; Craniocerebral Traum | 2001 |
Metabolic acidosis, rhabdomyolysis, and cardiovascular collapse after prolonged propofol infusion.
Topics: Acidosis; Adolescent; Electrocardiography; Fatal Outcome; Female; Head Injuries, Closed; Heart Disea | 2001 |
Propofol.
Topics: Adolescent; Heart Failure; Humans; Infusions, Intravenous; Male; Propofol; Renal Insufficiency; Rhab | 2002 |
Propofol.
Topics: Adult; Heart Failure; Humans; Infusions, Intravenous; Male; Propofol; Renal Insufficiency; Rhabdomyo | 2002 |