propofol and Respiratory Tract Diseases

propofol has been researched along with Respiratory Tract Diseases in 8 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Respiratory Tract Diseases: Diseases involving the RESPIRATORY SYSTEM.

Research

Studies (8)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Duration of Recovery After the Endoscopic Procedure

"After completion of the procedure, the patient stood in the examination room monitored continuously by a nurse. When patients responded to normal verbal command, they were asked to sit up and were offered a drink. This was considered the early recovery time.~If they were able to stand unassisted by the bed and had stable hemodynamics parameters (saturation>90 % on room air and blood pressure and heart rate within 20 % of baseline), they were transferred to a locker room accompanied by a relative. The discharge criteria included ability to stand unassisted and tolerate clear liquids once dressed. Once a patient met discharge criteria, they were allowed to leave at their own discretion" (NCT01428882)
Timeframe: Up to 1 hour after colonoscopy

Level of Sedation Throughout the Entire Procedure

Assessment every two minutes of the level of sedation during the endoscopic procedure, rating it as minimal, moderate or deep. (NCT01428882)
Timeframe: Up to 1 hour after introduction of the colonoscope

Rate of Patients and Physician Satisfaction With Sedation

"Endoscopists and patients rated their satisfaction with sedation in a 10-cm visual analogue scale after discharge.The patients were contacted 24-48 h after the procedure to answer a questionnaire regarding if they remembered scope insertion or scope removal and willingness to repeat it with a similar protocol and rated their satisfaction and pain perception from 0 to 10. This phone survey was done by the nurse specifically making the measurements in the endoscopy room, who was blinded to the sedation regimen.~For the interpretation of results of the 0-10 point numerical scale, 0 stands for 'extremely dissatisfied with sedation level during the endoscopic procedure', whereas 10 stands for 'extremely satisfied with sedation level during the endoscopic procedure." (NCT01428882)
Timeframe: Up to 1 hour after colonoscopy for endoscopists and up to 48 hours for patients

Rate of Sedation-related Complications During the Procedure and the Recovery Phases

The following events were considered complications of procedural sedation: a decline in oxygen saturation to less than 85 % longer than 30 s after increasing the oxygen flow rate to 5 L/min and transient propofol interruption, a heart rate less than 40 beats per minute and blood pressure less than 80/50 mmHg. Major complications were defined as need for mechanical ventilation or any cardiorespiratory event requiring anaesthesiologist assistance. (NCT01428882)
Timeframe: Up to two hours, including colonoscopy performance and recovery period

Trials

1 trial available for propofol and Respiratory Tract Diseases

Other Studies

7 other studies available for propofol and Respiratory Tract Diseases