Page last updated: 2024-11-03

propofol and Respiratory Insufficiency

propofol has been researched along with Respiratory Insufficiency in 103 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"This study primarily aims to examine whether an additional capnographic monitoring-based intervention can reduce the incidence of hypoxia in older patients during gastrointestinal endoscopy under propofol and sufentanil sedation."9.69Capnographic monitoring reduces hypoxia incidence in older patients undergoing gastrointestinal endoscopy under propofol sedation: study protocol for a multicenter randomized controlled trial. ( Chen, S; Cheng, X; Lian, Q; Su, D; Yu, W; Zhang, J; Zhou, R, 2023)
"BACKGROUND This prospective, randomized, controlled study evaluated the efficacy and safety of remimazolam tosilate sedation with adjuvant sufentanil, relative to propofol, for Chinese patients with liver cirrhosis undergoing gastroscopy."9.51Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study. ( Cao, Y; Chi, P; Lv, W; Quan, Z; Xue, FS; Zhou, C, 2022)
"To discuss mainly the use of propofol and barbiturates in the anesthesia of refractory status epilepticus (RSE)."8.84Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and cons. ( Kälviäinen, R; Parviainen, I; Ruokonen, E, 2007)
" Propofol's disadvantages include the induction of respiratory depression and apnea."7.79Coadministration of the AMPAKINE CX717 with propofol reduces respiratory depression and fatal apneas. ( Ding, X; Greer, JJ; Lenal, F; Ren, J; Yang, M, 2013)
"Apnea was determined to be the serious adverse effect for all dogs."7.70Respiratory depression and apnea induced by propofol in dogs. ( Gadawski, JE; Muir, WW, 1998)
"Propofol was promptly discontinued."5.91Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19. ( Henley, E; Siddiqui, MN; Xue, B, 2023)
"Low-dose etomidate combined with oxycodone and midazolam for endoscopic injection sclerotherapy could reduce the incidence of hypoxia without increasing the incidence of complications."5.69Application of low-dose etomidate combined with oxycodone and midazolam in endoscopic injection sclerotherapy. ( Cao, Y; Hao, S; Quan, Z; Yao, J; Zhou, C, 2023)
"This study primarily aims to examine whether an additional capnographic monitoring-based intervention can reduce the incidence of hypoxia in older patients during gastrointestinal endoscopy under propofol and sufentanil sedation."5.69Capnographic monitoring reduces hypoxia incidence in older patients undergoing gastrointestinal endoscopy under propofol sedation: study protocol for a multicenter randomized controlled trial. ( Chen, S; Cheng, X; Lian, Q; Su, D; Yu, W; Zhang, J; Zhou, R, 2023)
"Remimazolam was associated with a lower rate of hypotension in elderly patients undergoing upper gastrointestinal endoscopy under deep sedation/anaesthesia than propofol."5.51Remimazolam versus propofol for deep sedation/anaesthesia in upper gastrointestinal endoscopy in elderly patients: A multicenter, randomized controlled trial. ( Fu, L; Huang, H; Huang, Y; Jiang, J; Liao, Y; Ling, W; Lu, K; Ma, C; Pan, M; Qin, Z; Ran, X; Wang, M; Wei, N; Wei, Q; Wei, S; Wei, Y; Xiong, B, 2022)
"BACKGROUND This prospective, randomized, controlled study evaluated the efficacy and safety of remimazolam tosilate sedation with adjuvant sufentanil, relative to propofol, for Chinese patients with liver cirrhosis undergoing gastroscopy."5.51Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study. ( Cao, Y; Chi, P; Lv, W; Quan, Z; Xue, FS; Zhou, C, 2022)
" Propofol is the most widely used agent for induction of anesthesia and sedation by anesthesiologists."5.41Remimazolam ( Chang, Y; Chi, KY; Huang, YT, 2023)
"Propofol was commenced in all patients at a mean infusion rate of 18."5.38Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation. ( Drewitz, I; Heitmann, K; Hoffmann, BA; Rostock, T; Salukhe, TV; Steven, D; Willems, S, 2012)
"Remifentanil is an ultra-short acting narcotic, and is excellent for relieving pain maintaining stable hemodynamics."5.35[Successful management with remifentanil of tracheal stent insertion keeping spontaneous breathing in a patient with severe respiratory insufficiency]. ( Koshimichi, T; Okutani, R; Tsunetoh, T, 2009)
"We determine whether high-flow oxygen reduces the incidence of hypoxia by 20% in adults receiving propofol for emergency department (ED) sedation compared with room air."5.15The utility of high-flow oxygen during emergency department procedural sedation and analgesia with propofol: a randomized, controlled trial. ( Chudnofsky, CR; Deitch, K; Dominici, P; Latta, D; Salamanca, Y, 2011)
" Episodes of apnea or hypoventilation detected by capnography were compared with the occurrence of hypoxemia."5.14Capnography is superior to pulse oximetry for the detection of respiratory depression during colonoscopy. ( Barbado, A; Cacho, G; Fernández-Rodríguez, CM; Lledó, JL; Ojea, R; Pérez-Calle, JL, 2010)
"The use of supplemental alfentanil with propofol for procedural sedation did not result in a difference in reported pain or recall immediately after the procedure."5.14Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department. ( Biros, MH; Gray, RO; Miner, JR; Stephens, D, 2009)
"In adults receiving ED propofol sedation, the addition of capnography to standard monitoring reduced hypoxia and provided advance warning for all hypoxic events."5.14Does end tidal CO2 monitoring during emergency department procedural sedation and analgesia with propofol decrease the incidence of hypoxic events? A randomized, controlled trial. ( Chudnofsky, CR; Deitch, K; Dominici, P; Latta, D; Miner, J, 2010)
"We determine whether supplemental oxygen reduces the incidence of hypoxia by 20% compared with breathing room air in adult study patients receiving propofol for emergency department procedural sedation."5.13The utility of supplemental oxygen during emergency department procedural sedation with propofol: a randomized, controlled trial. ( Chudnofsky, CR; Deitch, K; Dominici, P, 2008)
"To discuss mainly the use of propofol and barbiturates in the anesthesia of refractory status epilepticus (RSE)."4.84Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and cons. ( Kälviäinen, R; Parviainen, I; Ruokonen, E, 2007)
" A 42-year-old man receiving treatment for RP underwent open reduction and internal fixation of a femur fracture under spinal anesthesia and with sedation by propofol and remifentanil."4.12Respiratory Failure during BIS-Guided Sedation in a Patient with Relapsing Polychondritis: A Case Report. ( Chon, J; Hong, S; Kwon, H; Lee, J; Moon, H; Park, H, 2022)
" Fentanyl (77%) and hydromorphone (48%) were the most common intravenous opioids used to manage pain."3.91Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation. ( Abrams, D; Agerstrand, C; Brodie, D; Dzierba, AL; Madahar, P; Muir, J, 2019)
"A 37-year-old female patient with myotonic dystrophy was scheduled for laparoscopic cholecystectomy for gall stone under general anesthesia with continuous propofol infusion."3.85Use of Sugammadex in a Patient with Myotonic Dystrophy Undergoing Laparoscopic Cholecystectomy. ( Matsuda, S; Murao, K; Nakamura, K; Shingu, K; Shirakawa, M; Uno, R, 2017)
" Propofol's disadvantages include the induction of respiratory depression and apnea."3.79Coadministration of the AMPAKINE CX717 with propofol reduces respiratory depression and fatal apneas. ( Ding, X; Greer, JJ; Lenal, F; Ren, J; Yang, M, 2013)
"Apnea was determined to be the serious adverse effect for all dogs."3.70Respiratory depression and apnea induced by propofol in dogs. ( Gadawski, JE; Muir, WW, 1998)
"Propofol may be recommended as an anaesthetic agent in patients with chronic respiratory insufficiency since: it prevents the increase in bronchial resistances resulting from the administration of opioids; it possesses a bronchodilator effect, comparable with that of flunitrazepam; it ensures rapid recovery, which would favour patient's co-operation postoperatively."3.69[Use of Diprivan in chronic respiratory insufficiency]. ( Bourgain, JL, 1994)
" The aim of this study was to investigate the effects of remimazolam besylate combined with alfentanil in patients undergoing fiberoptic bronchoscopy with preserved spontaneous breathing."3.30Effectiveness of remimazolam besylate combined with alfentanil for fiberoptic bronchoscopy with preserved spontaneous breathing: a prospective, randomized, controlled clinical trial. ( Chen, ZJ; Li, JY; Wang, JF; Xu, L; Yu, L; Zhang, L, 2023)
"The incidences of respiratory depression episodes and involuntary movement were less in the group M than those in the group N (0/40 vs."3.30Effects of intravenous administration of magnesium sulfate in propofol-based sedation for ERCP in elderly patients: a randomized, double-blind, placebo-controlled study. ( Chen, J; Chen, Y; Li, XL; Liu, CH; Qian, K; Wang, JQ, 2023)
"The rates of respiratory depression (1."3.11Effect of additional equipotent fentanyl or sufentanil administration on recovery profiles during propofol-remifentanil-based anaesthesia in patients undergoing gynaecologic laparoscopic surgery: a randomized clinical trial. ( Huang, D; Huang, J; Jian, Q; Li, P; Ma, J; Xie, H; Zeng, W; Zhang, C, 2022)
"Haemodynamic events and respiratory depression in the RT group were less frequent than those in the propofol group ((6/39 vs."3.11Remimazolam tosilate compared with propofol for gastrointestinal endoscopy in elderly patients: a prospective, randomized and controlled study. ( Guo, J; Han, S; Qian, Y; Shi, Q; Xu, J; Zhang, X, 2022)
"Fentanyl is an opioid receptor agonist and a commonly used sedative."3.11Efficacy of Analgesic Propofol/Esketamine and Propofol/Fentanyl for Painless Induced Abortion: A Randomized Clinical Trial. ( Jin, S; Xin, N; Yan, W, 2022)
"The incidence of respiratory depression was significantly reduced in the RT group compared with the propofol group (9."3.11Effect of Remimazolam Tosilate on Respiratory Depression in Elderly Patients Undergoing Gastroscopy: A Multicentered, Prospective, and Randomized Study. ( Hu, B; Jiang, K; Shi, W; Tan, C; Tan, S; Xiao, S; Zhang, S; Zhang, Y; Zhou, Y; Zou, X, 2022)
"Remimazolam tosilate (RT) is a new short-acting GABA(A) receptor agonist, having potential to be an effective option for procedural sedation."3.01Remimazolam tosilate in upper gastrointestinal endoscopy: A multicenter, randomized, non-inferiority, phase III trial. ( Bai, H; Bao, HG; Chen, SH; Huang, YG; Ji, FH; Jin, XJ; Li, L; Li, XK; Li, YJ; Luo, AL; Lv, JR; Min, S; Pan, CX; Tian, M; Wang, Q; Wang, S; Yu, YH; Yuan, TM; Zhang, J; Zhong, TD; Zou, XH, 2021)
"Incidence of postanaesthesia respiratory depression in PACU as well as anaesthesia recovery, emergence delirium, postoperative nausea and vomiting, rescue analgesia, duration of PACU and hospital stay, and any other adverse events will be assessed at the given study time point."3.01Study protocol for a randomised controlled clinical trial comparing desflurane-based versus propofol-based anaesthesia on postanaesthesia respiratory depression in patients with obstructive sleep apnoea after major abdominal surgery. ( Chen, D; Chen, G; Gong, Y; Hou, L; Li, M; Liao, R; Wu, H; Wu, X; Xue, H; Yang, F; Yang, Y; Zhang, R, 2021)
"Hypoxemia was defined as a pulse oximetry reading of <92%."2.84Randomized trial of a novel double lumen nasopharyngeal catheter versus traditional nasal cannula during total intravenous anesthesia for gastrointestinal procedures. ( Alvis, BD; Hester, D; Higgins, M; King, AB; Taylor, S, 2017)
"The frequency of myoclonus was significantly higher in the etomidate group (22/64 [34."2.84Etomidate versus propofol sedation for complex upper endoscopic procedures: a prospective double-blinded randomized controlled trial. ( Choi, MH; Jang, HJ; Kae, SH; Kim, JH; Kim, MG; Koh, DH; Lee, J; Park, SW, 2017)
"Postoperative respiratory depression was defined as rate <10/min, hypercapnia/hypercarbia-arterial CO2 tension >50 mmHg or SO2 <90 while hypotension was defined as a decrease of 20 % in mean blood pressure compared to initial values."2.82Propofol-ketamine combination: a choice with less complications and better hemodynamic stability compared to propofol? On a prospective study in a group of colonoscopy patients. ( Babayıgıt, M; Baykal Tutal, Z; Derelı, N; Gulec, H; Horasanlı, E; Inceoz, H; Kurtay, A, 2016)
"Propofol was associated with a longer time in PACU versus dexmedetomidine and remimazolam tosylate (1."2.82The Choice of Anesthetic Drugs in Outpatient Hysteroscopic Surgery: A Systematic Review and Network Meta-Analysis. ( An, L; Hou, K; Li, S; Peng, B; Wu, B; Zhang, Q; Zhao, H, 2022)
" Additional bolus/es was/were administered in the dosage similar to induction dose in case of inadequate sedation."2.78A double blind randomized trial of ketofol versus propofol for endodontic treatment of anxious pediatric patients. ( Gauba, K; Goyal, A; Jain, K; Kapur, A; Mittal, N, 2013)
"Using models of respiratory compromise, loss of response to esophageal instrumentation, and loss of responsiveness, the authors explored through simulation published dosing schemes for endoscopy using propofol alone and in combination with selected opioids."2.77A simulation study of common propofol and propofol-opioid dosing regimens for upper endoscopy: implications on the time course of recovery. ( Egan, TD; Johnson, KB; LaPierre, CD; Randall, BR, 2012)
"Main outcome measures were respiratory depression, nausea/vomiting, quality of intraoperative conditions, and discharge time."2.77Ketamine, propofol and low dose remifentanil versus propofol and remifentanil for ERCP outside the operating room: is ketamine not only a "rescue drug"? ( Al Malyan, M; Becchi, C; Fabbri, LP; Marsili, M; Nucera, M, 2012)
"We compare the frequency of respiratory depression during emergency department procedural sedation with ketamine plus propofol versus propofol alone."2.76A randomized controlled trial of ketamine/propofol versus propofol alone for emergency department procedural sedation. ( David, H; Shipp, J, 2011)
"Midazolam + alfentanil and propofol are equally safe for sedation during bronchoscopy."2.76Propofol safety in bronchoscopy: prospective randomized trial using transcutaneous carbon dioxide tension monitoring. ( Carmi, U; Fruchter, O; Kramer, MR; Rosengarten, D; Zemtzov, D, 2011)
"To demonstrate that respiratory depression associated with PR is more frequent during anesthesiologist-administered sedation (AAS) than during PCS."2.75A prospective, randomized, comparative trial evaluating respiratory depression during patient-controlled versus anesthesiologist-administered propofol-remifentanil sedation for elective colonoscopy. ( Ginsberg, GG; Kochman, ML; Lichtenstein, GR; Mandel, JE; Metz, DC, 2010)
"Propofol can cause significant respiratory depression, the management of which may require advanced airway management skills."2.75Slower administration of propofol preserves adequate respiration in children. ( Brant, R; Dosani, M; Dumont, G; Lim, J; Mark Ansermino, J; McCormack, J; Reimer, E, 2010)
"Propofol was administered until the patients did not respond to a verbal command."2.74Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy. ( Bulut, M; Ganidagli, S; Koruk, S; Mizrak, A; Oner, U, 2009)
"Propofol doses were reduced by 20% (P = 0."2.74Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: a centre randomised, cross-over, open-label study in the Netherlands. ( Bakker, J; Foudraine, NA; Mulder, PG; Rozendaal, FW; Schoen, A; Snellen, FF; Spronk, PE; van Zanten, AR, 2009)
"Respiratory depression was defined as a change in ETCO(2) >10, an oxygen saturation of <90% at any time, or an absent ETCO(2) waveform at any time."2.73The effect of the assignment of a pre-sedation target level on procedural sedation using propofol. ( Biros, M; Huber, D; Miner, JR; Nichols, S, 2007)
"Twenty-one patients (16, 6%) had respiratory depression [hypercarbia (ETco2 > 50 mm Hg) or hypoxia (oxygen saturation > 90% for over 1 minute)], 21 patients (16, 6%) had hypercarbia, and 4 patients (3."2.71The value of capnography during sedation or sedation/analgesia in pediatric minor procedures. ( Yapcoǧlu, H; Yldzdaş, D; Ylmaz, HL, 2004)
"As a result of the higher incidence of adverse respiratory effects with remifentanil and similar sedative effects, propofol is preferable for sedation during cervical plexus block in elderly patients with comorbid disease at the dosage used."2.70Remifentanil or propofol for sedation during carotid endarterectomy under cervical plexus block. ( Deusch, E; Fitzgerald, RD; Jellinek, H; Krenn, H; Oczenski, W, 2002)
"Remifentanil was administered as a loading dose of 0."2.69Remifentanil in combination with propofol for spontaneous ventilation anaesthesia. ( Luntley, JB; O'Connor, B; Ogg, TW; Peacock, JE; Reilly, CS; Shaikh, S; Watson, BJ, 1998)
" Half concluded that propofol was sufficiently safe; three reviews noted a higher occurrence of adverse events, particularly respiratory depression (upper estimate 1."2.53What Works and What's Safe in Pediatric Emergency Procedural Sedation: An Overview of Reviews. ( Evered, L; Foisy, M; Hartling, L; Klassen, TP; Lang, ES; Milne, A; Sinclair, D, 2016)
"There was no recurrence of muscle hypertonia, and she recovered fully without complications."1.91Positional Change Used to Manage Postextubation Respiratory Failure in a Child With Cerebral Palsy. ( Hidaka, K; Hirokawa, J; Hitosugi, T; Kanemaru, M; Oshima, Y; Yokoyama, T, 2023)
"Propofol was promptly discontinued."1.91Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19. ( Henley, E; Siddiqui, MN; Xue, B, 2023)
"Methohexital is a safe and effective option for procedural sedation for musculoskeletal procedures in the ED when compared with ketamine and propofol."1.72A Safety Comparison of Single-Agent Methohexital, Ketamine, or Propofol for Musculoskeletal Procedural Sedation in the Emergency Department. ( Kruggel, S; Mishler, A; Sullivan, L, 2022)
"We present a case of rapid respiratory failure in an otherwise healthy and young patient who used a vaporiser containing tetrahydrocannabinol (THC) during the month prior to admission."1.56Sedation challenges in patients with E-cigarette, or vaping, product use-associated lung injury (EVALI). ( Markowski, LM; Maslonka, MA; Miller, PJ; Schertz, AR, 2020)
"Propofol was used for the first sedation procedure."1.51Intravenous Sedation in Arnold-Chiari Malformation With Respiratory Failure. ( Goi, T; Nakamura, E; Nakamura, K; Shionoya, Y; Sunada, K, 2019)
"Episodes of respiratory depression during the immediate postoperative recovery period (Phase I post-anesthesia recovery) have been associated with respiratory complications during Phase II recovery."1.48Isoflurane and postoperative respiratory depression following laparoscopic surgery: A retrospective propensity-matched analysis. ( Cavalcante, AN; Gurrieri, C; Schroeder, DR; Sprung, J; Weingarten, TN, 2018)
" The model may be useful for identifying optimal dosing schedules for these drugs in a combination that provides adequate sedation but avoids respiratory depression."1.43Modeling Respiratory Depression Induced by Remifentanil and Propofol during Sedation and Analgesia Using a Continuous Noninvasive Measurement of pCO2. ( Borrat, X; Castells, A; Castellví-Bel, S; Gambús, PL; Hannam, JA; Jensen, EW; Muñoz, J; Pedroso, A; Trocóniz, IF; Valencia, JF, 2016)
"The objective was to assess whether respiratory depression and supportive airway measures occurring during procedural sedation are associated with changes in peripheral tissue oxygen saturation (StO2 )."1.43Using Near Infrared Spectroscopy for Tissue Oxygenation Monitoring During Procedural Sedation: The Occurrence of Peripheral Tissue Oxygenation Changes With Respiratory Depression and Supportive Airway Measures. ( Driver, B; Miner, JR; Moore, JC; O'Brien-Lambert, A; Schick, A, 2016)
"To determine the risk factors for respiratory depression during retrobulbar block administration before vitreoretinal surgery."1.42Risk factors for respiratory depression in patients undergoing retrobulbar block for vitreoretinal surgery. ( Brock-Utne, JG; Drover, DR; He, L; Leng, JC; Leng, T; Silva, RA, 2015)
"A 20-month-old girl, with respiratory failure due to severe subcutaneous and mediastinal emphysema, was scheduled to undergo percutaneous drainage of emphysema and induction of extracorporeal membrane oxygenation."1.40[Anesthetic management of a patient with severe subcutaneous and mediastinal emphysema due to pertussis infection]. ( Ideno, S; Ishikawa, S; Mikasa, H; Miyazawa, N; Shinto, A; Wakamiya, R; Yamamoto, S, 2014)
"To evaluate the nature, frequency, and predictors of adverse events during the use of propofol by pediatric hospitalists."1.38Procedural sedation for diagnostic imaging in children by pediatric hospitalists using propofol: analysis of the nature, frequency, and predictors of adverse events and interventions. ( Carlson, DW; Depalma, LM; Mao, J; Srinivasan, M; Turmelle, M, 2012)
"Transient respiratory depression occurred in 13."1.38Induction dose of propofol for pediatric patients undergoing procedural sedation in the emergency department. ( Christich, AC; Edwards, CJ; Jasiak, KD; Patanwala, AE; Phan, H; Skrepnek, GH, 2012)
"Propofol was commenced in all patients at a mean infusion rate of 18."1.38Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation. ( Drewitz, I; Heitmann, K; Hoffmann, BA; Rostock, T; Salukhe, TV; Steven, D; Willems, S, 2012)
"Propofol was the most common induction agent [124 cases (76%)] and 157 patients (96%) received neuromuscular blocking agents."1.37Out-of-theatre tracheal intubation: prospective multicentre study of clinical practice and adverse events. ( Bowles, TM; Freshwater-Turner, DA; Janssen, DJ; Peden, CJ, 2011)
"Propofol is an effective sedative in advanced endoscopy."1.36Incidence of sedation-related complications with propofol use during advanced endoscopic procedures. ( Ansstas, MA; Azar, RR; Coté, GA; Early, DS; Edmundowicz, SA; Hovis, RM; Jonnalagadda, SS; Mullady, DK; Waldbaum, L, 2010)
"On contrary, Steinert disease is rarely revealed in the postoperative period."1.35[Anaesthetic management of patients with Steinert myotonia: two case reports]. ( Attof, Y; Bastien, O; Flamens, C; Lehot, JJ; Mahr, A, 2009)
"Propofol is a short acting intravenous anaesthetic, active agent of Diprivan."1.35Evaluation of a fatal propofol intoxication due to self administration. ( Klausz, G; Kristóf, I; Róna, K; Töro, K, 2009)
"Remifentanil is an ultra-short acting narcotic, and is excellent for relieving pain maintaining stable hemodynamics."1.35[Successful management with remifentanil of tracheal stent insertion keeping spontaneous breathing in a patient with severe respiratory insufficiency]. ( Koshimichi, T; Okutani, R; Tsunetoh, T, 2009)
"Propofol is an effective agent for use in procedural sedation and analgesia (PSA)."1.33Propofol by infusion protocol for ED procedural sedation. ( Bigelow, SK; Fay, K; Frank, LR; Hauff, SR; Strote, J, 2006)
"Propofol was administered during PSA to 792 patients during the respective reporting period at each center."1.33Propofol for emergency department procedural sedation and analgesia: a tale of three centers. ( Becker, C; Burton, JH; Miner, JR; Shipley, ER; Strout, TD; Thode, HC, 2006)
"Although the incidence of respiratory depression was higher in patients receiving deep sedation with propofol than in patients who were lightly sedated (17."1.32Use of deep intravenous sedation with propofol and the laryngeal mask airway during transesophageal echocardiography. ( Arens, J; Ferson, D; Sapire, K; Sinha, A; Swafford, J; Thakar, D, 2003)

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.97)18.7374
1990's5 (4.85)18.2507
2000's28 (27.18)29.6817
2010's44 (42.72)24.3611
2020's25 (24.27)2.80

Authors

AuthorsStudies
Wu, H1
Yang, F1
Zhang, R1
Xue, H1
Yang, Y1
Liao, R1
Li, M1
Wu, X1
Chen, D1
Chen, G1
Gong, Y1
Hou, L1
Zhang, C2
Huang, D1
Zeng, W1
Ma, J1
Li, P1
Jian, Q1
Huang, J1
Xie, H1
Jiang, Z1
Liu, Y1
Zhang, X2
Ting, CK2
Wang, X2
Brewer, LM1
Yu, L2
Guo, J1
Qian, Y1
Han, S1
Shi, Q1
Xu, J1
Kruggel, S1
Mishler, A1
Sullivan, L1
Cao, Y2
Chi, P1
Zhou, C2
Lv, W1
Quan, Z2
Xue, FS1
Xin, N1
Yan, W1
Jin, S1
Li, S1
Wu, B1
Peng, B1
Zhang, Q1
Zhao, H1
Hou, K1
An, L1
Zhang, W1
Yin, H1
Xu, Y1
Fang, Z1
Wang, W1
Shi, H1
Lu, K1
Wei, S1
Ling, W1
Wei, Y1
Ran, X1
Huang, H1
Wang, M1
Wei, N1
Liao, Y1
Qin, Z1
Pan, M1
Wei, Q1
Fu, L1
Xiong, B1
Ma, C1
Jiang, J1
Huang, Y1
Hu, B2
Jiang, K2
Shi, W2
Xiao, S2
Zhang, S2
Zhang, Y2
Zhou, Y2
Tan, C2
Tan, S2
Zou, X2
Yao, J1
Hao, S1
Lee, J3
Moon, H1
Hong, S1
Chon, J1
Kwon, H1
Park, H1
Viderman, D1
Nabidollayeva, F1
Bilotta, F1
Abdildin, YG1
Lian, Q1
Chen, S1
Cheng, X1
Zhang, J2
Yu, W1
Zhou, R1
Su, D1
Li, X1
Wei, J1
Shen, N1
Lu, T1
Xing, J1
Mai, K1
Li, J1
Hei, Z1
Chen, C1
Siddiqui, MN1
Henley, E1
Xue, B1
Chang, Y1
Huang, YT2
Chi, KY1
Chen, J1
Qian, K1
Liu, CH1
Li, XL1
Chen, Y1
Wang, JQ1
Zhang, L1
Xu, L1
Wang, JF1
Li, JY1
Chen, ZJ1
Yazawa, N1
Nakamura, Y1
Takemasa, A1
Uchida, N1
Kushima, Y1
Masawa, M1
Okutomi, H1
Soda, S1
Ikeda, N1
Arai, R1
Chibana, K1
Niho, S1
Shimizu, Y1
Hirokawa, J1
Hidaka, K1
Kanemaru, M1
Hitosugi, T1
Oshima, Y1
Yokoyama, T1
Chen, SH1
Yuan, TM1
Bai, H1
Tian, M1
Pan, CX1
Bao, HG1
Jin, XJ1
Ji, FH1
Zhong, TD1
Wang, Q1
Lv, JR1
Wang, S1
Li, YJ1
Yu, YH1
Luo, AL1
Li, XK1
Min, S1
Li, L1
Zou, XH1
Huang, YG1
Maslonka, MA1
Schertz, AR1
Markowski, LM1
Miller, PJ1
Boshkovska Spaseski, M1
Spaseski, D1
King, AB1
Alvis, BD1
Hester, D1
Taylor, S1
Higgins, M1
Cavalcante, AN1
Gurrieri, C1
Sprung, J1
Schroeder, DR1
Weingarten, TN1
Uno, R1
Matsuda, S1
Murao, K1
Nakamura, K2
Shirakawa, M1
Shingu, K1
Liou, JY1
Teng, WN1
Mandell, MS1
Tsou, MY1
Schick, A2
Driver, B2
Moore, JC2
Fagerstrom, E1
Miner, JR5
Doğanay, F1
Ak, R1
Alışkan, H1
Abut, S1
Sümer, E1
Onur, Ö1
Shionoya, Y1
Nakamura, E1
Goi, T1
Sunada, K1
Dzierba, AL1
Abrams, D1
Madahar, P1
Muir, J1
Agerstrand, C1
Brodie, D1
Ren, J1
Lenal, F1
Yang, M1
Ding, X1
Greer, JJ1
Dahan, A1
Roozekrans, M1
van der Schrier, R1
Smith, T1
Aarts, L1
Mannocchi, G1
Napoleoni, F1
Napoletano, S1
Pantano, F1
Santoni, M1
Tittarelli, R1
Arbarello, P1
Mittal, N1
Goyal, A1
Gauba, K1
Kapur, A1
Jain, K1
Tominaga, H1
Hatori, E1
Takeda, J2
Morisaki, H1
Chang, YJ1
Jung, WS1
Son, WR1
Jo, YY1
Ideno, S1
Miyazawa, N1
Ishikawa, S1
Wakamiya, R1
Shinto, A1
Mikasa, H1
Yamamoto, S1
Umezawa, N1
Arisaka, H1
Sakuraba, S1
Sugita, T1
Matsumoto, A1
Kaku, Y1
Yoshida, K1
Kuwana, S1
Silva, RA1
Leng, JC1
He, L1
Brock-Utne, JG1
Drover, DR1
Leng, T1
Baykal Tutal, Z1
Gulec, H1
Derelı, N1
Babayıgıt, M1
Kurtay, A1
Inceoz, H1
Horasanlı, E1
Ersoy, A1
Kara, D1
Ervatan, Z1
Çakırgöz, M1
Kıran, Ö1
Hannam, JA1
Borrat, X1
Trocóniz, IF1
Valencia, JF1
Jensen, EW1
Pedroso, A1
Muñoz, J1
Castellví-Bel, S1
Castells, A1
Gambús, PL1
O'Brien-Lambert, A1
Mieloszyk, RJ1
Guo, MG1
Verghese, GC1
Andolfatto, G1
Heldt, T1
Krauss, BS1
Hartling, L1
Milne, A1
Foisy, M1
Lang, ES1
Sinclair, D1
Klassen, TP1
Evered, L1
Kim, MG1
Park, SW1
Kim, JH1
Kae, SH1
Jang, HJ1
Koh, DH1
Choi, MH1
Yoshida, S1
Nishikawa, K1
Shimodate, Y1
Igarashi, M1
Namiki, A1
Liatsi, D1
Tsapas, B1
Pampori, S1
Tsagourias, M1
Pneumatikos, I1
Matamis, D1
Rozendaal, FW1
Spronk, PE1
Snellen, FF1
Schoen, A1
van Zanten, AR1
Foudraine, NA1
Mulder, PG1
Bakker, J1
Beccaria, P1
Cabrini, L1
Garancini, MP1
Colombo, S1
Mahr, A1
Attof, Y1
Flamens, C1
Bastien, O1
Lehot, JJ1
Mizrak, A1
Koruk, S1
Ganidagli, S1
Bulut, M1
Oner, U1
Klausz, G1
Róna, K1
Kristóf, I1
Töro, K1
Coté, GA2
Hovis, RM2
Ansstas, MA1
Waldbaum, L2
Azar, RR2
Early, DS2
Edmundowicz, SA2
Mullady, DK2
Jonnalagadda, SS2
Deitch, K3
Miner, J1
Chudnofsky, CR3
Dominici, P3
Latta, D2
Gray, RO1
Stephens, D1
Biros, MH1
Tsunetoh, T1
Okutani, R1
Koshimichi, T1
Cacho, G1
Pérez-Calle, JL1
Barbado, A1
Lledó, JL1
Ojea, R1
Fernández-Rodríguez, CM1
Mandel, JE1
Lichtenstein, GR1
Metz, DC1
Ginsberg, GG1
Kochman, ML1
Hovis, CE1
Dosani, M1
McCormack, J1
Reimer, E1
Brant, R1
Dumont, G1
Lim, J1
Mark Ansermino, J1
Kashiwagi, M1
Osaka, Y1
Onimaru, H1
David, H1
Shipp, J1
LaPierre, CD2
Johnson, KB2
Randall, BR2
White, JL1
Egan, TD2
Salamanca, Y1
Bowles, TM1
Freshwater-Turner, DA1
Janssen, DJ1
Peden, CJ1
Krejcie, TC1
Avram, MJ1
Carmi, U1
Kramer, MR1
Zemtzov, D1
Rosengarten, D1
Fruchter, O1
Sayfo, S1
Vakil, KP1
Alqaqa'a, A1
Flippin, H1
Bhakta, D1
Yadav, AV1
Miller, JM1
Groh, WJ1
Salukhe, TV1
Willems, S1
Drewitz, I1
Steven, D1
Hoffmann, BA1
Heitmann, K1
Rostock, T1
Srinivasan, M1
Turmelle, M1
Depalma, LM1
Mao, J1
Carlson, DW1
Jasiak, KD1
Phan, H1
Christich, AC1
Edwards, CJ1
Skrepnek, GH1
Patanwala, AE1
Fabbri, LP1
Nucera, M1
Marsili, M1
Al Malyan, M1
Becchi, C1
De La Mora-González, JF1
Robles-Cervantes, JA1
Mora-Martínez, JM1
Barba-Alvarez, F1
Llontop-Pisfil, Ede L1
González-Ortiz, M1
Martínez-Abundis, E1
Llamas-Moreno, JF1
Espinel Bermúdez, MC1
Krenn, H1
Deusch, E1
Jellinek, H1
Oczenski, W1
Fitzgerald, RD1
Izurieta, R1
Rabatin, JT1
Ferson, D1
Thakar, D1
Swafford, J1
Sinha, A1
Sapire, K1
Arens, J1
Green, SM2
Krauss, B1
Bouillon, T1
Bruhn, J1
Radu-Radulescu, L1
Andresen, C1
Cohane, C1
Shafer, SL1
Yldzdaş, D1
Yapcoǧlu, H1
Ylmaz, HL1
Moser, B1
Lirk, P1
Lechner, M1
Gottardis, M1
Burton, JH1
Shipley, ER1
Strout, TD1
Becker, C1
Thode, HC1
Casagrande, AM1
Frank, LR1
Strote, J1
Hauff, SR1
Bigelow, SK1
Fay, K1
Anderson, JL1
Junkins, E1
Pribble, C1
Guenther, E1
Huber, D1
Nichols, S1
Biros, M1
Catena, V1
Del Monte, DD1
Rubini, A1
Guccione, C1
Ricagna, F1
Gangeri, G1
De Zen, GF1
Parviainen, I1
Kälviäinen, R1
Ruokonen, E1
Cong, Y1
Sun, X1
Bourgain, JL1
Spens, HJ1
Drummond, GB1
Muir, WW1
Gadawski, JE1
Sternlo, JE1
Sandin, RH1
Peacock, JE1
Luntley, JB1
O'Connor, B1
Reilly, CS1
Ogg, TW1
Watson, BJ1
Shaikh, S1
Khamiees, M1
Amoateng-Adjepong, Y1
Manthous, CA1
Bloor, GK1
Jones, MJ1
Turner, DA1

Clinical Trials (27)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Investigation of the Dose Range of Remimazolam Besylate in Different Age Groups of Adults and Its Effects on Hemodynamics[NCT06009991]1,876 participants (Anticipated)Interventional2023-07-17Recruiting
Anesthesia Endoscope Mask is Applied to Sedation Upper Gastrointestinal Endoscopic Diagnosis and Treatment: Multi-center, Prospective, Randomized Control, Open Clinical Research[NCT06085859]1,208 participants (Anticipated)Interventional2023-10-18Recruiting
Triple Drug Response Surface Modeling for Patients Receiving Airway Managements[NCT03813875]100 participants (Actual)Observational2019-06-12Completed
The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia[NCT05525351]60 participants (Anticipated)Observational2022-10-31Not yet recruiting
Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy[NCT05437497]264 participants (Anticipated)Interventional2021-08-01Recruiting
Effect of Clonidine vs. Dexmedetomidine in Addition to Standard Treatment in Agitated Delirium in Intensive Care Patients: Pilot Study.[NCT04758936]Phase 450 participants (Anticipated)Interventional2021-02-01Recruiting
Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in Adult Patients Undergoing Colonoscopy[NCT06131905]Phase 2/Phase 360 participants (Anticipated)Interventional2024-01-01Not yet recruiting
Incidence of Sedation Related Complications With Propofol Alone Versus Propofol With Benzodiazepines and Opiates in a High Risk Group Undergoing Advanced Endoscopic Procedures: A Randomized Controlled Trial[NCT01315158]36 participants (Actual)Interventional2011-01-31Terminated (stopped due to - The research team is not able to obtain the necessary support to continue the study.)
Ciprofol vs Propofol for Reducing Hypoxia Incidence in Intravenous Anesthesia During Elective Endoscopic Retrograde Cholangiopancreatography-A Randomized Double Blinded Controlled Trial.[NCT06015074]124 participants (Anticipated)Interventional2023-10-01Not yet recruiting
A Randomised Control Trial to Determine Whether Intervention Based on a Microstream Capnography-based Ventilation Monitoring System Will Decrease Hypoxaemaia During Intravenous Sedation With Midazolam.[NCT01949012]190 participants (Actual)Interventional2013-10-31Completed
Combination Ketamine and Propofol vs Propofol for Emergency Department Sedation: A Prospective Randomized Trial[NCT01269307]99 participants (Actual)Interventional2010-06-30Completed
A Randomized Double-blind Trial to Evaluate Ketamine-propofol Combination vs. Propofol Alone for Procedural Sedation and Analgesia in the Emergency Department.[NCT01211158]Phase 3284 participants (Actual)Interventional2010-12-31Completed
Safety and Efficacy of Propofol Only Sedation in Oral and Maxillofacial Surgery[NCT01227174]Phase 4169 participants (Anticipated)Interventional2011-01-31Not yet recruiting
[NCT02039453]160 participants (Anticipated)Interventional2013-09-30Recruiting
A Phase IV, Randomized, Double-Blind, Controlled Study of the Effects of Patient-Controlled Sedation vs. Anesthesiologist-Administered Sedation With Propofol and Remifentanil on Rate of Disordered Breathing in Subjects Undergoing Elective Colonoscopy[NCT00868920]50 participants (Actual)Interventional2008-01-31Completed
Intravenous Sedation and Analgesia Using Propofol, Fentanyl and Ketamine (PFK) Versus General Anesthesia in Minor Urological Procedures.[NCT04285528]200 participants (Actual)Interventional2019-04-17Completed
Magnesium Sulphate Versus Fentanyl as Adjuvants to Propofol Xylocaine Combination for Conscious Sedation During Chronic Subdural Haematoma Surgery. Comparative Study[NCT03548493]Phase 234 participants (Actual)Interventional2018-04-10Completed
An Evaluation of the Utility of the ExSpiron Respiratory Variation Monitor During Upper GI Endoscopy[NCT02310230]100 participants (Anticipated)Interventional2014-09-30Recruiting
Effect of High Flow Nasal Cannula vs. Standard Care on Respiratory Stability in Pediatric Procedural Sedation: A Randomized Controlled Pilot Trial[NCT02930525]50 participants (Actual)Interventional2016-09-30Completed
Airway Code Calls - Survey of Management[NCT03035786]300 participants (Anticipated)Observational [Patient Registry]2016-11-30Recruiting
Effect of BIS Monitoring on Propofol Usage During Elective Bronchoscopy[NCT01592513]80 participants (Anticipated)Interventional2012-04-30Recruiting
High Flow Nasal Cannula (HFNC) Versus Standard Low Flow Nasal Cannula (LFNC) in Patients With Atrial Fibrillation Undergoing Radiofrequency Catheter Ablation (RFCA) Under Deep Desaturation.[NCT04842253]210 participants (Anticipated)Interventional2022-01-04Recruiting
A Pilot Study to Investigate the Efficacy and Safety of Dexmedetomidine and Fentanyl Versus Midazolam and Remifentanil for Sedation in Patients Undergoing Ablation Procedures for Treatment of a Tachyarrhythmia[NCT03451227]6 participants (Actual)Interventional2017-12-01Terminated (stopped due to Unable to recruit eligible participants)
[NCT01855581]3,739 participants (Anticipated)Observational2012-11-30Recruiting
Supraglottic Airway Use for Transesophageal Echocardiography: a Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease. (SGA-TEE)[NCT04939220]110 participants (Anticipated)Interventional2024-02-29Not yet recruiting
Effect of Dexmedetomidine of Gastrointestinal Motility[NCT04798482]Phase 422 participants (Actual)Interventional2021-09-14Completed
Application of Capnography Monitoring on the General Care Nursing Unit[NCT00457080]60 participants Interventional2006-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Who Experience Airway Maneuvers

In high risk patients (meeting at least of 1 of 3 criteria: ASA ≥ 3, BMI ≥ 30, those at risk for OSA) undergoing advanced endoscopy procedures, compare the number of participants who experience airway maneuvers (AMs) when sedated with propofol alone versus propofol in combination with benzodiazepines and opioids. (NCT01315158)
Timeframe: One day (during procedure)

Interventionparticipants (Number)
Propofol+Benzo/Opioids4
Propofol Alone4

Number of Participants Who Experience Other Sedation Related Complications

Compare the number of participants who experience other sedation related complications such as hypotension, hypoxemia and need for termination of the procedure between the two groups (NCT01315158)
Timeframe: One day (during procedure)

Interventionparticipants (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Number of Participants Who Experience Symptoms of Nausea and Vomiting Will be Compared Between the Two Groups

The number of participants who experience symptoms of nausea and vomiting in the two groups of patients will be recorded. This will be recorded during the follow-up phone call made 24-48 hours after the procedure. (NCT01315158)
Timeframe: 24-48 hours

Interventionparticipants (Number)
Propofol+Benzo/Opioids2
Propofol Alone1

Predictors of Sedation Related Complications as Measured by Early Procedure Termination for an Alternative Sedation Related Complication

(NCT01315158)
Timeframe: One year

Interventionincidences (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Predictors of Sedation Related Complications as Measured by Hypopnea/Apnea (Defined as Fewer Than 6 Breaths/Minute Based on Capnography)

(NCT01315158)
Timeframe: One year

Interventionincidences (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Predictors of Sedation Related Complications as Measured by the Incidences of Hypotension (Defined as Systolic Blood Pressure of Less Than 90mmHg or a Decrease of More Than 25% From Baseline)

(NCT01315158)
Timeframe: One year

Interventionincidences (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Predictors of Sedation Related Complications as Measured by the Number of Participants Who Experience Hypoxemia (Defined as a Pulse Oximetry <90% for Any Duration)

(NCT01315158)
Timeframe: One year

Interventionparticipants (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Reviews

7 reviews available for propofol and Respiratory Insufficiency

ArticleYear
The Choice of Anesthetic Drugs in Outpatient Hysteroscopic Surgery: A Systematic Review and Network Meta-Analysis.
    Disease markers, 2022, Volume: 2022

    Topics: Ambulatory Surgical Procedures; Anesthetics; Dexmedetomidine; Female; Humans; Hysteroscopy; Network

2022
Comparison of dexmedetomidine and propofol for sedation in awake craniotomy: A meta-analysis.
    Clinical neurology and neurosurgery, 2023, Volume: 226

    Topics: Conscious Sedation; Craniotomy; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Respirat

2023
Remimazolam
    PeerJ, 2023, Volume: 11

    Topics: Anesthesia; Benzodiazepines; Bradycardia; Conscious Sedation; Dizziness; Humans; Hypotension; Pain;

2023
What Works and What's Safe in Pediatric Emergency Procedural Sedation: An Overview of Reviews.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2016, Volume: 23, Issue:5

    Topics: Anesthetics, Intravenous; Child; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Hypote

2016
Sedation during mechanical ventilation: a systematic review.
    Critical care medicine, 2002, Volume: 30, Issue:12

    Topics: Adult; Anesthetics; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Pro

2002
Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and cons.
    Neurological research, 2007, Volume: 29, Issue:7

    Topics: Anesthetics, Intravenous; Anticonvulsants; Barbiturates; Dose-Response Relationship, Drug; Humans; M

2007
Recurrent respiratory depression after total intravenous anaesthesia with propofol and alfentanil.
    Anaesthesia, 1998, Volume: 53, Issue:4

    Topics: Adult; Alfentanil; Anesthetics, Combined; Anesthetics, Intravenous; Female; Humans; Male; Middle Age

1998

Trials

42 trials available for propofol and Respiratory Insufficiency

ArticleYear
Study protocol for a randomised controlled clinical trial comparing desflurane-based versus propofol-based anaesthesia on postanaesthesia respiratory depression in patients with obstructive sleep apnoea after major abdominal surgery.
    BMJ open, 2021, 10-19, Volume: 11, Issue:10

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Humans; Propofol

2021
Effect of additional equipotent fentanyl or sufentanil administration on recovery profiles during propofol-remifentanil-based anaesthesia in patients undergoing gynaecologic laparoscopic surgery: a randomized clinical trial.
    BMC anesthesiology, 2022, 04-29, Volume: 22, Issue:1

    Topics: Anesthesia; Delirium; Dizziness; Female; Fentanyl; Humans; Laparoscopy; Nausea; Propofol; Remifentan

2022
Remimazolam tosilate compared with propofol for gastrointestinal endoscopy in elderly patients: a prospective, randomized and controlled study.
    BMC anesthesiology, 2022, 06-10, Volume: 22, Issue:1

    Topics: Aged; Benzodiazepines; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Pain; Propofol;

2022
Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study.
    Medical science monitor : international medical journal of experimental and clinical research, 2022, Jun-16, Volume: 28

    Topics: Benzodiazepines; China; Gastroscopy; Humans; Hypnotics and Sedatives; Hypotension; Liver Cirrhosis;

2022
Efficacy of Analgesic Propofol/Esketamine and Propofol/Fentanyl for Painless Induced Abortion: A Randomized Clinical Trial.
    BioMed research international, 2022, Volume: 2022

    Topics: Abortion, Induced; Analgesics; Female; Fentanyl; Humans; Hypnotics and Sedatives; Ketamine; Pregnanc

2022
The effect of varying inhaled oxygen concentrations of high-flow nasal cannula oxygen therapy during gastroscopy with propofol sedation in elderly patients: a randomized controlled study.
    BMC anesthesiology, 2022, 11-02, Volume: 22, Issue:1

    Topics: Aged; Airway Obstruction; Cannula; Gastroscopy; Humans; Hypoxia; Oxygen; Oxygen Inhalation Therapy;

2022
Remimazolam versus propofol for deep sedation/anaesthesia in upper gastrointestinal endoscopy in elderly patients: A multicenter, randomized controlled trial.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:12

    Topics: Aged; Anesthesia; Benzodiazepines; Bradycardia; Deep Sedation; Endoscopy, Gastrointestinal; Female;

2022
Effect of Remimazolam Tosilate on Respiratory Depression in Elderly Patients Undergoing Gastroscopy: A Multicentered, Prospective, and Randomized Study.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Aged; Gastroscopy; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies; Respiratory Insuf

2022
Effect of Remimazolam Tosilate on Respiratory Depression in Elderly Patients Undergoing Gastroscopy: A Multicentered, Prospective, and Randomized Study.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Aged; Gastroscopy; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies; Respiratory Insuf

2022
Effect of Remimazolam Tosilate on Respiratory Depression in Elderly Patients Undergoing Gastroscopy: A Multicentered, Prospective, and Randomized Study.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Aged; Gastroscopy; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies; Respiratory Insuf

2022
Effect of Remimazolam Tosilate on Respiratory Depression in Elderly Patients Undergoing Gastroscopy: A Multicentered, Prospective, and Randomized Study.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Aged; Gastroscopy; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies; Respiratory Insuf

2022
Application of low-dose etomidate combined with oxycodone and midazolam in endoscopic injection sclerotherapy.
    International journal of clinical pharmacology and therapeutics, 2023, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Etomidate; Humans; Hypoxia; Midazolam; Middle Age

2023
Capnographic monitoring reduces hypoxia incidence in older patients undergoing gastrointestinal endoscopy under propofol sedation: study protocol for a multicenter randomized controlled trial.
    Trials, 2023, Mar-15, Volume: 24, Issue:1

    Topics: Aged; Capnography; Conscious Sedation; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives;

2023
Modified Manual Chest Compression for Prevention and Treatment of Respiratory Depression in Patients Under Deep Sedation During Upper Gastrointestinal Endoscopy: Two Randomized Controlled Trials.
    Anesthesia and analgesia, 2023, 10-01, Volume: 137, Issue:4

    Topics: Conscious Sedation; Deep Sedation; Endoscopy, Gastrointestinal; Gastroscopy; Humans; Oxygen; Propofo

2023
Effects of intravenous administration of magnesium sulfate in propofol-based sedation for ERCP in elderly patients: a randomized, double-blind, placebo-controlled study.
    BMC geriatrics, 2023, Jul-07, Volume: 23, Issue:1

    Topics: Administration, Intravenous; Aged; Cholangiopancreatography, Endoscopic Retrograde; Double-Blind Met

2023
Effectiveness of remimazolam besylate combined with alfentanil for fiberoptic bronchoscopy with preserved spontaneous breathing: a prospective, randomized, controlled clinical trial.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:13

    Topics: Alfentanil; Benzodiazepines; Bronchoscopy; Humans; Hypnotics and Sedatives; Hypotension; Propofol; P

2023
Remimazolam tosilate in upper gastrointestinal endoscopy: A multicenter, randomized, non-inferiority, phase III trial.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:2

    Topics: Adult; Aged; Anesthesia Recovery Period; Benzodiazepines; Conscious Sedation; Endoscopy, Gastrointes

2021
Randomized trial of a novel double lumen nasopharyngeal catheter versus traditional nasal cannula during total intravenous anesthesia for gastrointestinal procedures.
    Journal of clinical anesthesia, 2017, Volume: 38

    Topics: Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Cannula; Cathet

2017
Randomized Clinical Trial Comparing Procedural Amnesia and Respiratory Depression Between Moderate and Deep Sedation With Propofol in the Emergency Department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2019, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Aged; Conscious Sedation; Deep Sedation; Female; Humans; Hypnotics and Sedatives;

2019
A double blind randomized trial of ketofol versus propofol for endodontic treatment of anxious pediatric patients.
    The Journal of clinical pediatric dentistry, 2013,Summer, Volume: 37, Issue:4

    Topics: Child; Child, Preschool; Dental Anxiety; Double-Blind Method; Drug Combinations; Female; Humans; Hyp

2013
Propofol-ketamine combination: a choice with less complications and better hemodynamic stability compared to propofol? On a prospective study in a group of colonoscopy patients.
    Irish journal of medical science, 2016, Volume: 185, Issue:3

    Topics: Anesthetics, Combined; Colonoscopy; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; H

2016
Sedation in hypoalbuminemic geriatric patients under spinal anesthesia in hip surgery. Midazolam or Propofol?
    Saudi medical journal, 2015, Volume: 36, Issue:10

    Topics: Age Factors; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Spinal; Arthroplasty,

2015
Etomidate versus propofol sedation for complex upper endoscopic procedures: a prospective double-blinded randomized controlled trial.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:3

    Topics: Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Deep Sedation; Double-Blind Method; Endoscopy

2017
[Efficacy of spinal anesthesia with small-dose lidocaine in ambulatory prostate biopsy procedures for elderly patients : comparison with propofol anesthesia].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:5

    Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, General; Anesthesia, Spinal; Biopsy; Humans; Hypot

2008
Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: a centre randomised, cross-over, open-label study in the Netherlands.
    Intensive care medicine, 2009, Volume: 35, Issue:2

    Topics: Cross-Over Studies; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Netherlands; Piperid

2009
Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy.
    Journal of anesthesia, 2009, Volume: 23, Issue:1

    Topics: Adult; Anesthesia; Bipolar Disorder; Blood Pressure; Depressive Disorder, Major; Dexmedetomidine; El

2009
Does end tidal CO2 monitoring during emergency department procedural sedation and analgesia with propofol decrease the incidence of hypoxic events? A randomized, controlled trial.
    Annals of emergency medicine, 2010, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Capnography; Carbon Dioxide; Emergency S

2010
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Randomized clinical trial of propofol with and without alfentanil for deep procedural sedation in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Adult; Alfentanil; Anesthetics, Intravenous; Deep Sedation; Drug Combinations; Emergency Medical Ser

2009
Capnography is superior to pulse oximetry for the detection of respiratory depression during colonoscopy.
    Revista espanola de enfermedades digestivas, 2010, Volume: 102, Issue:2

    Topics: Adult; Aged; Apnea; Capnography; Carbon Dioxide; Colonoscopy; Computer Systems; Conscious Sedation;

2010
A prospective, randomized, comparative trial evaluating respiratory depression during patient-controlled versus anesthesiologist-administered propofol-remifentanil sedation for elective colonoscopy.
    Gastrointestinal endoscopy, 2010, Volume: 72, Issue:1

    Topics: Academic Medical Centers; Adult; Aged; Analgesia, Patient-Controlled; Anesthesiology; Anesthetics, I

2010
A prospective, randomized, comparative trial evaluating respiratory depression during patient-controlled versus anesthesiologist-administered propofol-remifentanil sedation for elective colonoscopy.
    Gastrointestinal endoscopy, 2010, Volume: 72, Issue:1

    Topics: Academic Medical Centers; Adult; Aged; Analgesia, Patient-Controlled; Anesthesiology; Anesthetics, I

2010
A prospective, randomized, comparative trial evaluating respiratory depression during patient-controlled versus anesthesiologist-administered propofol-remifentanil sedation for elective colonoscopy.
    Gastrointestinal endoscopy, 2010, Volume: 72, Issue:1

    Topics: Academic Medical Centers; Adult; Aged; Analgesia, Patient-Controlled; Anesthesiology; Anesthetics, I

2010
A prospective, randomized, comparative trial evaluating respiratory depression during patient-controlled versus anesthesiologist-administered propofol-remifentanil sedation for elective colonoscopy.
    Gastrointestinal endoscopy, 2010, Volume: 72, Issue:1

    Topics: Academic Medical Centers; Adult; Aged; Analgesia, Patient-Controlled; Anesthesiology; Anesthetics, I

2010
Slower administration of propofol preserves adequate respiration in children.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:11

    Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Carbon Dioxide; Child

2010
A randomized controlled trial of ketamine/propofol versus propofol alone for emergency department procedural sedation.
    Annals of emergency medicine, 2011, Volume: 57, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Conscious Sedation; Double-Blin

2011
A randomized controlled trial of ketamine/propofol versus propofol alone for emergency department procedural sedation.
    Annals of emergency medicine, 2011, Volume: 57, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Conscious Sedation; Double-Blin

2011
A randomized controlled trial of ketamine/propofol versus propofol alone for emergency department procedural sedation.
    Annals of emergency medicine, 2011, Volume: 57, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Conscious Sedation; Double-Blin

2011
A randomized controlled trial of ketamine/propofol versus propofol alone for emergency department procedural sedation.
    Annals of emergency medicine, 2011, Volume: 57, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Conscious Sedation; Double-Blin

2011
An exploration of remifentanil-propofol combinations that lead to a loss of response to esophageal instrumentation, a loss of responsiveness, and/or onset of intolerable ventilatory depression.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:3

    Topics: Adult; Anesthetics, Combined; Anesthetics, Intravenous; Awareness; Chi-Square Distribution; Cross-Ov

2011
The utility of high-flow oxygen during emergency department procedural sedation and analgesia with propofol: a randomized, controlled trial.
    Annals of emergency medicine, 2011, Volume: 58, Issue:4

    Topics: Adult; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Hy

2011
Propofol safety in bronchoscopy: prospective randomized trial using transcutaneous carbon dioxide tension monitoring.
    Respiration; international review of thoracic diseases, 2011, Volume: 82, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia Recovery Period; Anesthetics, Intravenous; Bl

2011
A simulation study of common propofol and propofol-opioid dosing regimens for upper endoscopy: implications on the time course of recovery.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Intravenous; Dos

2012
A simulation study of common propofol and propofol-opioid dosing regimens for upper endoscopy: implications on the time course of recovery.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Intravenous; Dos

2012
A simulation study of common propofol and propofol-opioid dosing regimens for upper endoscopy: implications on the time course of recovery.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Intravenous; Dos

2012
A simulation study of common propofol and propofol-opioid dosing regimens for upper endoscopy: implications on the time course of recovery.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Intravenous; Dos

2012
Ketamine, propofol and low dose remifentanil versus propofol and remifentanil for ERCP outside the operating room: is ketamine not only a "rescue drug"?
    Medical science monitor : international medical journal of experimental and clinical research, 2012, Volume: 18, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Analgesics; Blood Pressure; Cholangiopancreatography, End

2012
Hemodynamic effects of dexmedetomidine--fentanyl vs. nalbuphine--propofol in plastic surgery.
    Middle East journal of anaesthesiology, 2012, Volume: 21, Issue:4

    Topics: Analgesics, Opioid; Anesthetics, Intravenous; Blood Pressure; Dexmedetomidine; Drug Therapy, Combina

2012
Remifentanil or propofol for sedation during carotid endarterectomy under cervical plexus block.
    British journal of anaesthesia, 2002, Volume: 89, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthetics, Intravenous; Cervical Plexus; Conscious Sedation; Endarterecto

2002
Mixed-effects modeling of the intrinsic ventilatory depressant potency of propofol in the non-steady state.
    Anesthesiology, 2004, Volume: 100, Issue:2

    Topics: Adult; Bayes Theorem; Carbon Dioxide; Female; Humans; Hypnotics and Sedatives; Male; Models, Biologi

2004
The value of capnography during sedation or sedation/analgesia in pediatric minor procedures.
    Pediatric emergency care, 2004, Volume: 20, Issue:3

    Topics: Adolescent; Analgesia; Analgesics; Capnography; Carbon Dioxide; Child; Child, Preschool; Conscious S

2004
The effect of the assignment of a pre-sedation target level on procedural sedation using propofol.
    The Journal of emergency medicine, 2007, Volume: 32, Issue:3

    Topics: Adult; Conscious Sedation; Electroencephalography; Emergency Service, Hospital; Fractures, Bone; Hum

2007
The utility of supplemental oxygen during emergency department procedural sedation with propofol: a randomized, controlled trial.
    Annals of emergency medicine, 2008, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Aged; Capnography; Chi-Square Distribution; Child; Child, Preschool; Conscious Se

2008
Ventilatory effects of eltanolone during induction of anaesthesia: comparison with propofol and thiopentone.
    British journal of anaesthesia, 1996, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Anesthetics, Intravenous; Apnea; Female; Humans; Male; Middle Aged; Postoperative

1996
Remifentanil in combination with propofol for spontaneous ventilation anaesthesia.
    British journal of anaesthesia, 1998, Volume: 80, Issue:4

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Dose-Response Relationship, D

1998

Other Studies

54 other studies available for propofol and Respiratory Insufficiency

ArticleYear
Response surface model comparison and combinations for remifentanil and propofol in describing response to esophageal instrumentation and adverse respiratory events.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2022, Volume: 121, Issue:12

    Topics: Anesthesia; Anesthetics, Intravenous; Esophagus; Humans; Propofol; Remifentanil; Respiratory Insuffi

2022
A Safety Comparison of Single-Agent Methohexital, Ketamine, or Propofol for Musculoskeletal Procedural Sedation in the Emergency Department.
    The Journal of emergency medicine, 2022, Volume: 63, Issue:2

    Topics: Adult; Analgesics; Anesthetics, Intravenous; Conscious Sedation; Emergency Service, Hospital; Humans

2022
Respiratory Failure during BIS-Guided Sedation in a Patient with Relapsing Polychondritis: A Case Report.
    Medicina (Kaunas, Lithuania), 2022, Dec-28, Volume: 59, Issue:1

    Topics: Adult; Anesthesia; Humans; Male; Polychondritis, Relapsing; Propofol; Respiration; Respiratory Insuf

2022
Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19.
    BMJ case reports, 2023, May-04, Volume: 16, Issue:5

    Topics: Atrial Fibrillation; COVID-19; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Prop

2023
Transcutaneous gas monitoring is a useful tool to detect respiratory depression during bronchoscopy performed under propofol sedation.
    Respiratory investigation, 2023, Volume: 61, Issue:6

    Topics: Bronchoscopy; Carbon Dioxide; Conscious Sedation; Fentanyl; Humans; Hypnotics and Sedatives; Midazol

2023
Positional Change Used to Manage Postextubation Respiratory Failure in a Child With Cerebral Palsy.
    Anesthesia progress, 2023, 09-01, Volume: 70, Issue:3

    Topics: Adolescent; Cerebral Palsy; Child; Female; Humans; Muscle Hypertonia; Muscle Spasticity; Propofol; R

2023
Sedation challenges in patients with E-cigarette, or vaping, product use-associated lung injury (EVALI).
    BMJ case reports, 2020, Sep-02, Volume: 13, Issue:9

    Topics: Acute Lung Injury; Analgesia; Computed Tomography Angiography; Deep Sedation; Dose-Response Relation

2020
Green Urine.
    The New England journal of medicine, 2020, Dec-03, Volume: 383, Issue:23

    Topics: Bilirubin; Color; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Respiratory Insuffic

2020
Isoflurane and postoperative respiratory depression following laparoscopic surgery: A retrospective propensity-matched analysis.
    Bosnian journal of basic medical sciences, 2018, Feb-20, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, In

2018
Use of Sugammadex in a Patient with Myotonic Dystrophy Undergoing Laparoscopic Cholecystectomy.
    Masui. The Japanese journal of anesthesiology, 2017, Volume: 66, Issue:5

    Topics: Adult; Androstanols; Anesthesia, Epidural; Anesthesia, General; Cholecystectomy, Laparoscopic; Femal

2017
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
    British journal of anaesthesia, 2018, Volume: 120, Issue:6

    Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug S

2018
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
    British journal of anaesthesia, 2018, Volume: 120, Issue:6

    Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug S

2018
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
    British journal of anaesthesia, 2018, Volume: 120, Issue:6

    Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug S

2018
Adaptation of non-linear mixed amount with zero amount response surface model for analysis of concentration-dependent synergism and safety with midazolam, alfentanil, and propofol sedation.
    British journal of anaesthesia, 2018, Volume: 120, Issue:6

    Topics: Adult; Aged; Alfentanil; Conscious Sedation; Drug Administration Schedule; Drug Combinations; Drug S

2018
The Effects of Intravenous Lipid Emulsion Therapy in the Prevention of Depressive Effects of Propofol on Cardiovascular and Respiratory Systems: An Experimental Animal Study.
    Medicina (Kaunas, Lithuania), 2018, Dec-25, Volume: 55, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Fat Emulsions, Intravenous; Heart Ra

2018
Intravenous Sedation in Arnold-Chiari Malformation With Respiratory Failure.
    Anesthesia progress, 2019,Spring, Volume: 66, Issue:1

    Topics: Adult; Anesthesia; Arnold-Chiari Malformation; Humans; Hypercapnia; Male; Propofol; Respiratory Insu

2019
Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation.
    Journal of critical care, 2019, Volume: 53

    Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Attitude of Health Personnel; Benzo

2019
Coadministration of the AMPAKINE CX717 with propofol reduces respiratory depression and fatal apneas.
    Anesthesiology, 2013, Volume: 118, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Apnea; Disease Models, Animal; Drug Therapy, Co

2013
Primum non nocere or how to resolve drug-induced respiratory depression.
    Anesthesiology, 2013, Volume: 118, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Apnea; Isoxazoles; Male; Propofol; Respiratory Insufficiency

2013
Fatal self administration of tramadol and propofol: a case report.
    Journal of forensic and legal medicine, 2013, Volume: 20, Issue:6

    Topics: Analgesics, Opioid; Drug Overdose; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair;

2013
[Anesthetic management of a neonate with congenital cystic adenomatoid malformation].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:1

    Topics: Androstanols; Anesthesia, General; Cystic Adenomatoid Malformation of Lung, Congenital; Female; Huma

2014
Discordance between train-of-four response and clinical symptoms in a patient with amyotrophic lateral sclerosis.
    Acta medica Okayama, 2014, Volume: 68, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Fema

2014
[Anesthetic management of a patient with severe subcutaneous and mediastinal emphysema due to pertussis infection].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:6

    Topics: Airway Management; Anesthesia; Drainage; Extracorporeal Membrane Oxygenation; Female; Humans; Infant

2014
Orexin-B antagonized respiratory depression induced by sevoflurane, propofol, and remifentanil in isolated brainstem-spinal cords of neonatal rats.
    Respiratory physiology & neurobiology, 2015, Jan-01, Volume: 205

    Topics: Anesthetics; Animals; Animals, Newborn; Brain Stem; Disease Models, Animal; Intracellular Signaling

2015
Risk factors for respiratory depression in patients undergoing retrobulbar block for vitreoretinal surgery.
    Ophthalmic surgery, lasers & imaging retina, 2015, Volume: 46, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia, Conduction; Anesthetics, Combined; Anestheti

2015
Modeling Respiratory Depression Induced by Remifentanil and Propofol during Sedation and Analgesia Using a Continuous Noninvasive Measurement of pCO2.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 356, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Intravenous; Blood Gas Monitoring,

2016
Using Near Infrared Spectroscopy for Tissue Oxygenation Monitoring During Procedural Sedation: The Occurrence of Peripheral Tissue Oxygenation Changes With Respiratory Depression and Supportive Airway Measures.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2016, Volume: 23, Issue:1

    Topics: Adult; Aged; Anesthesia; Capnography; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; K

2016
Clustering of capnogram features to track state transitions during procedural sedation.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2015, Volume: 2015

    Topics: Anesthetics, Intravenous; Anxiety; Capnography; Case-Control Studies; Cluster Analysis; Conscious Se

2015
Respiratory, metabolic and hemodynamic effects of clonidine in ventilated patients presenting with withdrawal syndrome.
    Intensive care medicine, 2009, Volume: 35, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Calorimetry, Indirect; Carbon Dioxide; Clonidine; Electrocardiogra

2009
Recurarisation in a surgical ward.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:6

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, General; Anes

2008
[Anaesthetic management of patients with Steinert myotonia: two case reports].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:2

    Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Delayed Emergence from Anesthesia; Extracorpore

2009
Evaluation of a fatal propofol intoxication due to self administration.
    Journal of forensic and legal medicine, 2009, Volume: 16, Issue:5

    Topics: Accidents; Drug Overdose; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans;

2009
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:2

    Topics: Adult; Aged; Anesthetics; Attitude of Health Personnel; Body Mass Index; Deep Sedation; Endoscopy, D

2010
[Successful management with remifentanil of tracheal stent insertion keeping spontaneous breathing in a patient with severe respiratory insufficiency].
    Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:10

    Topics: Aged; Anesthesia, Intravenous; Bronchoscopes; Humans; Male; Piperidines; Propofol; Remifentanil; Res

2009
A screening instrument for sleep apnea predicts airway maneuvers in patients undergoing advanced endoscopic procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:8

    Topics: Aged; Deep Sedation; Endoscopy; Female; Humans; Male; Mass Screening; Middle Aged; Propofol; Respira

2010
Optical imaging of propofol-induced central respiratory depression in medulla-spinal cord preparations from newborn rats.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Medulla Oblongata; Membrane Potentials; Neurons

2011
Out-of-theatre tracheal intubation: prospective multicentre study of clinical practice and adverse events.
    British journal of anaesthesia, 2011, Volume: 107, Issue:5

    Topics: Airway Management; Capnography; Critical Care; Emergency Medical Services; Emergency Service, Hospit

2011
When Duzitol does not do it all: the two sides of drug synergy.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:3

    Topics: Anesthetics, Combined; Anesthetics, Intravenous; Esophagus; Female; Humans; Male; Piperidines; Propo

2011
A retrospective analysis of proceduralist-directed, nurse-administered propofol sedation for implantable cardioverter-defibrillator procedures.
    Heart rhythm, 2012, Volume: 9, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Cardiac Pacing, Artificial; Conscious Sedation; Defibrillators, Impl

2012
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012, Volume: 14, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St

2012
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012, Volume: 14, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St

2012
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012, Volume: 14, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St

2012
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012, Volume: 14, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St

2012
Procedural sedation for diagnostic imaging in children by pediatric hospitalists using propofol: analysis of the nature, frequency, and predictors of adverse events and interventions.
    The Journal of pediatrics, 2012, Volume: 160, Issue:5

    Topics: Age Distribution; Child; Child, Preschool; Cohort Studies; Confidence Intervals; Conscious Sedation;

2012
Induction dose of propofol for pediatric patients undergoing procedural sedation in the emergency department.
    Pediatric emergency care, 2012, Volume: 28, Issue:5

    Topics: Adolescent; Anesthetics, Intravenous; Child; Child, Preschool; Conscious Sedation; Dose-Response Rel

2012
Use of deep intravenous sedation with propofol and the laryngeal mask airway during transesophageal echocardiography.
    Journal of cardiothoracic and vascular anesthesia, 2003, Volume: 17, Issue:4

    Topics: Adult; Aged; Airway Obstruction; Anesthesiology; Anesthetics, Intravenous; Cardiology; Drug Therapy,

2003
Propofol in emergency medicine: pushing the sedation frontier.
    Annals of emergency medicine, 2003, Volume: 42, Issue:6

    Topics: Adult; Anesthesia, General; Child; Clinical Protocols; Conscious Sedation; Emergency Medical Service

2003
General anaesthesia in a patient with motor neuron disease.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:11

    Topics: Amyotrophic Lateral Sclerosis; Anesthesia, General; Anesthetics, Intravenous; Atracurium; Carcinoma;

2004
Propofol for emergency department procedural sedation and analgesia: a tale of three centers.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2006, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Antiemetics; Child; Child, Preschool; Conscio

2006
Propofol for office oral and maxillofacial anesthesia: the case against low-dose ketamine.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2006, Volume: 64, Issue:4

    Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Dissoci

2006
Propofol by infusion protocol for ED procedural sedation.
    The American journal of emergency medicine, 2006, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Clinical Protocols; Conscious Sedation; Delusions; Dose-Response Relationsh

2006
Research advances in procedural sedation and analgesia.
    Annals of emergency medicine, 2007, Volume: 49, Issue:1

    Topics: Analgesia; Capnography; Child; Conscious Sedation; Emergency Service, Hospital; Etomidate; Humans; H

2007
Capnography and depth of sedation during propofol sedation in children.
    Annals of emergency medicine, 2007, Volume: 49, Issue:1

    Topics: Adolescent; Arm Injuries; Capnography; Child; Conscious Sedation; Emergency Service, Hospital; Fract

2007
Capnography and depth of sedation during propofol sedation in children.
    Annals of emergency medicine, 2007, Volume: 49, Issue:1

    Topics: Adolescent; Arm Injuries; Capnography; Child; Conscious Sedation; Emergency Service, Hospital; Fract

2007
Capnography and depth of sedation during propofol sedation in children.
    Annals of emergency medicine, 2007, Volume: 49, Issue:1

    Topics: Adolescent; Arm Injuries; Capnography; Child; Conscious Sedation; Emergency Service, Hospital; Fract

2007
Capnography and depth of sedation during propofol sedation in children.
    Annals of emergency medicine, 2007, Volume: 49, Issue:1

    Topics: Adolescent; Arm Injuries; Capnography; Child; Conscious Sedation; Emergency Service, Hospital; Fract

2007
Pediatric emergency medicine: legal briefs.
    Pediatric emergency care, 2007, Volume: 23, Issue:3

    Topics: Acidosis; Administration, Cutaneous; Adult; Asphyxia; Brain Damage, Chronic; Burns, Chemical; Child;

2007
Anesthesia and myotonic dystrophy (Steinert's syndrome). The role of total intravenous anesthesia with propofol, cisatracurium and remifentanyl. Case report.
    Minerva anestesiologica, 2007, Volume: 73, Issue:9

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracurium; Humans; Male; Myotonic Dystroph

2007
Mask adaptor--a novel method of positive pressure ventilation during propofol deep sedation for upper GI endoscopy.
    Gastrointestinal endoscopy, 2008, Volume: 68, Issue:1

    Topics: Aged; Blood Gas Analysis; Cohort Studies; Conscious Sedation; Dose-Response Relationship, Drug; Endo

2008
[Use of Diprivan in chronic respiratory insufficiency].
    Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:4

    Topics: Airway Resistance; Anesthesia, Intravenous; Chronic Disease; Humans; Propofol; Respiration; Respirat

1994
Respiratory depression and apnea induced by propofol in dogs.
    American journal of veterinary research, 1998, Volume: 59, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Apnea; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Fe

1998
Propofol infusion is associated with a higher rapid shallow breathing index in patients preparing to wean from mechanical ventilation.
    Respiratory care, 2002, Volume: 47, Issue:2

    Topics: Anesthetics, Intravenous; APACHE; Cohort Studies; Humans; Infusions, Intravenous; Middle Aged; Posit

2002
Absence of clinically significant neonatal respiratory depression after prolonged maternal propofol administration.
    Anaesthesia, 1987, Volume: 42, Issue:11

    Topics: Adult; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Phenols; Pregnancy; Propofol; Respi

1987