propofol has been researched along with Propofol Infusion Syndrome in 16 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Propofol Infusion Syndrome: Rare and often fatal drug complication which affects patients undergoing long-term treatment with high doses of PROPOFOL. It is characterized by METABOLIC ACIDOSIS; HYPERLIPIDEMIA; RHABDOMYOLYSIS; cardiovascular CIRCULATORY COLLAPSE; CARDIAC FAILURE; and KIDNEY FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol infusion syndrome is a rare, potentially fatal condition first described in children in the 1990s and later reported in adults." | 9.01 | Propofol infusion syndrome: a structured literature review and analysis of published case reports. ( Bellamy, MC; Hemphill, S; Hopkins, PM; McMenamin, L, 2019) |
| "Propofol Infusion Syndrome (PRIS) is a rare but potentially lethal adverse reaction secondary to the continuous intravenous infusion of this drug." | 8.98 | [Propofol Infusion Syndrome in a refractory epileptic status case]. ( Ammann, R; Correa, A; Diettes, A; López, N; Riveros, R; Torres, F, 2018) |
| "Propofol infusion syndrome (PRIS) is a rare entity that could lead to profound cardiogenic shock (CS)." | 8.31 | VA-ECMO rescue therapy in propofol infusion syndrome after cardiac surgery. ( Báez, GP; Cabello, AG; González, AU; Martín, MP; San Román Calvar, JA; Stepanenko, A, 2023) |
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 7.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "To this day, the pathophysiology and risk factors of propofol infusion syndrome (PRIS) remain unknown." | 7.96 | Suspected propofol infusion syndrome during normal targeted propofol concentration. ( Ichikawa, T; Kamata, K; Masui, K; Okuyama, K; Ozaki, M, 2020) |
| "Propofol infusion syndrome (PRIS) is one of the severe complications which occur during continuous venous infusion of propofol, and has a high mortality rate." | 7.96 | [Propofol Infusion Syndrome Treated Successfully by Early Diagnosis]. ( Sakamoto, M; Shimada, M, 2020) |
| "Propofol was promptly discontinued." | 5.91 | Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19. ( Henley, E; Siddiqui, MN; Xue, B, 2023) |
| "Propofol Infusion Syndrome (PRIS) is a rare but potentially lethal adverse reaction secondary to the continuous intravenous infusion of this drug." | 4.98 | [Propofol Infusion Syndrome in a refractory epileptic status case]. ( Ammann, R; Correa, A; Diettes, A; López, N; Riveros, R; Torres, F, 2018) |
| "Propofol infusion syndrome (PRIS) is a rare entity that could lead to profound cardiogenic shock (CS)." | 4.31 | VA-ECMO rescue therapy in propofol infusion syndrome after cardiac surgery. ( Báez, GP; Cabello, AG; González, AU; Martín, MP; San Román Calvar, JA; Stepanenko, A, 2023) |
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 3.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "To this day, the pathophysiology and risk factors of propofol infusion syndrome (PRIS) remain unknown." | 3.96 | Suspected propofol infusion syndrome during normal targeted propofol concentration. ( Ichikawa, T; Kamata, K; Masui, K; Okuyama, K; Ozaki, M, 2020) |
| "Propofol infusion syndrome (PRIS) is one of the severe complications which occur during continuous venous infusion of propofol, and has a high mortality rate." | 3.96 | [Propofol Infusion Syndrome Treated Successfully by Early Diagnosis]. ( Sakamoto, M; Shimada, M, 2020) |
| "Propofol was infused at 1." | 1.91 | Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS. ( Babu, VK; Garcia-Fernandez, A; Perez Del Nogal, G; Rojas, P, 2023) |
| "Propofol was promptly discontinued." | 1.91 | Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19. ( Henley, E; Siddiqui, MN; Xue, B, 2023) |
| "Propofol has a unique profile that makes it an attractive sedative agent in many clinical settings." | 1.43 | Propofol Use in Israeli PICUs. ( Abu-Kishk, I; Berkovitch, M; Klin, B; Rosenfeld-Yehoshua, N, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 11 (68.75) | 2.80 |
| Authors | Studies |
|---|---|
| Martín, MP | 1 |
| Báez, GP | 1 |
| Cabello, AG | 1 |
| Stepanenko, A | 1 |
| San Román Calvar, JA | 1 |
| González, AU | 1 |
| Li, WK | 1 |
| Chen, XJC | 1 |
| Altshuler, D | 1 |
| Islam, S | 1 |
| Spiegler, P | 1 |
| Emerson, L | 1 |
| Bender, M | 1 |
| Honore, PM | 4 |
| Redant, S | 3 |
| Djimafo, P | 3 |
| Blackman, S | 3 |
| Bousbiat, I | 3 |
| Perriens, E | 3 |
| Preseau, T | 3 |
| Cismas, BV | 3 |
| Kaefer, K | 3 |
| Barreto Gutierrez, L | 3 |
| Anane, S | 3 |
| Gallerani, A | 3 |
| Attou, R | 3 |
| Babu, VK | 1 |
| Rojas, P | 1 |
| Perez Del Nogal, G | 1 |
| Garcia-Fernandez, A | 1 |
| Siddiqui, MN | 1 |
| Henley, E | 1 |
| Xue, B | 1 |
| Dell'Angela, L | 1 |
| Gatti, G | 1 |
| Morosin, M | 1 |
| Lardieri, G | 1 |
| Subirà González, A | 1 |
| Fernández Morales, M | 1 |
| Sánchez Royo, E | 1 |
| Boliart de San Félix, Y | 1 |
| Vila Lolo, C | 1 |
| Ichikawa, T | 1 |
| Okuyama, K | 1 |
| Kamata, K | 1 |
| Masui, K | 1 |
| Ozaki, M | 1 |
| Lucchetta, V | 1 |
| Bonvicini, D | 1 |
| Ballin, A | 1 |
| Tiberio, I | 1 |
| Sharma, B | 1 |
| Shimada, M | 1 |
| Sakamoto, M | 1 |
| López, N | 1 |
| Correa, A | 1 |
| Ammann, R | 1 |
| Diettes, A | 1 |
| Riveros, R | 1 |
| Torres, F | 1 |
| Hemphill, S | 1 |
| McMenamin, L | 1 |
| Bellamy, MC | 1 |
| Hopkins, PM | 1 |
| Şahin, T | 1 |
| Rosenfeld-Yehoshua, N | 1 |
| Klin, B | 1 |
| Berkovitch, M | 1 |
| Abu-Kishk, I | 1 |
| Spapen, HD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Study of Ciprofol for the Suppression of Cardiovascular Responses to Tracheal[NCT06095570] | Phase 4 | 150 participants (Anticipated) | Interventional | 2022-07-23 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propofol and Propofol Infusion Syndrome
| Article | Year |
|---|---|
[Propofol Infusion Syndrome in a refractory epileptic status case].
Topics: Anticonvulsants; Child; Female; Humans; Injections, Intravenous; Propofol; Propofol Infusion Syndrom | 2018 |
Propofol infusion syndrome: a structured literature review and analysis of published case reports.
Topics: Age Factors; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedat | 2019 |
14 other studies available for propofol and Propofol Infusion Syndrome
| Article | Year |
|---|---|
VA-ECMO rescue therapy in propofol infusion syndrome after cardiac surgery.
Topics: Adult; Cardiac Surgical Procedures; Extracorporeal Membrane Oxygenation; Female; Humans; Propofol; P | 2023 |
The incidence of propofol infusion syndrome in critically-ill patients.
Topics: Adult; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Propofol; Propofol Infusion Syn | 2022 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS.
Topics: Acidosis; Aged; COVID-19; Humans; Hyperlipidemias; Hypertriglyceridemia; Male; Propofol; Propofol In | 2023 |
Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19.
Topics: Atrial Fibrillation; COVID-19; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Prop | 2023 |
Propofol Infusion Syndrome: An Early and Unusual Electrocardiographic Pattern.
Topics: Anesthetics, Intravenous; Electrocardiography; Humans; Infusions, Intravenous; Propofol; Propofol In | 2020 |
Propofol infusion syndrome; are high doses always required?
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Chemical | 2020 |
Suspected propofol infusion syndrome during normal targeted propofol concentration.
Topics: Acidosis; Acidosis, Lactic; Adult; Anesthetics, Intravenous; Child; Humans; Infusions, Intravenous; | 2020 |
Propofol infusion syndrome in severe COVID-19.
Topics: Betacoronavirus; Conscious Sedation; Coronavirus Infections; COVID-19; Critical Illness; Humans; Hyp | 2020 |
Does use of propofol aggravate the inflammatory markers and cause propofol infusion syndrome in intubated cases of severe COVID-19 infections?
Topics: Antibodies, Monoclonal, Humanized; COVID-19 Drug Treatment; Humans; Hypertriglyceridemia; Propofol; | 2021 |
[Propofol Infusion Syndrome Treated Successfully by Early Diagnosis].
Topics: Aged, 80 and over; Early Diagnosis; Fever; Humans; Hypnotics and Sedatives; Male; Propofol; Propofol | 2020 |
PRIS may be diagnosed before ICU period for patients undergoing cardiopulmonary bypass.
Topics: Aged; Cardiopulmonary Bypass; Humans; Intensive Care Units; Male; Propofol; Propofol Infusion Syndro | 2016 |
Propofol Use in Israeli PICUs.
Topics: Child, Preschool; Drug Utilization Review; Female; Humans; Hypnotics and Sedatives; Infant; Infant, | 2016 |
Propofol infusion syndrome: early blood purification to the rescue?
Topics: Anesthetics, Intravenous; Humans; Infusions, Intravenous; Propofol; Propofol Infusion Syndrome; Synd | 2016 |