Page last updated: 2024-11-03

propofol and Primary Graft Dysfunction

propofol has been researched along with Primary Graft Dysfunction in 2 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Primary Graft Dysfunction: A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.

Research Excerpts

ExcerptRelevanceReference
"Sevoflurane has no significant added beneficial effect on ischemia-reperfusion injury compared to propofol."2.80Conditioning With Sevoflurane in Liver Transplantation: Results of a Multicenter Randomized Controlled Trial. ( Auler, JO; Beck-Schimmer, B; Bonvini, JM; Breitenstein, S; Clavien, PA; D'Albuquerque, LA; Debaerdemaeker, L; DeOliveira, ML; Dutkowski, P; Figueira, ER; Ganter, MT; Lesurtel, M; Oberkofler, CE; Puhan, MA; Reyntjens, K; Rocha Filho, JA; Rogiers, X; Schadde, E; Weber, A; Wouters, P, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beck-Schimmer, B1
Bonvini, JM1
Schadde, E1
Dutkowski, P1
Oberkofler, CE1
Lesurtel, M1
DeOliveira, ML1
Figueira, ER1
Rocha Filho, JA1
Auler, JO1
D'Albuquerque, LA1
Reyntjens, K1
Wouters, P1
Rogiers, X1
Debaerdemaeker, L1
Ganter, MT1
Weber, A1
Puhan, MA1
Clavien, PA1
Breitenstein, S1
Gajate Martín, L1
González, C1
Ruiz Torres, I1
Fernández Martín, C1
Martín Grande, A1
Elías Martín, E1
Parise Roux, D1
Del Rey Sánchez, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00913276]98 participants (Actual)Interventional2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for propofol and Primary Graft Dysfunction

ArticleYear
Conditioning With Sevoflurane in Liver Transplantation: Results of a Multicenter Randomized Controlled Trial.
    Transplantation, 2015, Volume: 99, Issue:8

    Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Aspartate Aminotransferases; Belgium

2015

Other Studies

1 other study available for propofol and Primary Graft Dysfunction

ArticleYear
Effects of the Hypnotic Agent on Primary Graft Dysfunction After Liver Transplantation.
    Transplantation proceedings, 2016, Volume: 48, Issue:10

    Topics: Aged; Alanine Transaminase; Anesthesia; Aspartate Aminotransferases; Female; Humans; Hypnotics and S

2016