propofol has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 16 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The objective was to evaluate EMLA (eutectic mixture of local anesthetics) cream as a pain reliever in conjunction with propofol in the setting of routine lumbar punctures." | 9.20 | Topical analgesia treats pain and decreases propofol use during lumbar punctures in a randomized pediatric leukemia trial. ( Bazzell, S; Roe, DJ; Saboda, K; Whitlow, PG; Wilson, C, 2015) |
| "Seizures occurred in two adolescents approximately six hours after sedation with propofol for bone marrow biopsy." | 7.68 | Delayed seizures following sedation with propofol. ( Fernandez, CV; Finley, GA; MacManus, B; Retallick, R; Sampson, SE, 1993) |
| " The objective was to evaluate EMLA (eutectic mixture of local anesthetics) cream as a pain reliever in conjunction with propofol in the setting of routine lumbar punctures." | 5.20 | Topical analgesia treats pain and decreases propofol use during lumbar punctures in a randomized pediatric leukemia trial. ( Bazzell, S; Roe, DJ; Saboda, K; Whitlow, PG; Wilson, C, 2015) |
| "During the first 12 hr following the procedures, patients experienced significantly less vomiting/retching and less disruption of activity while receiving ondansetron, and recorded significantly lower pain scores while receiving fentanyl." | 5.13 | Pediatric oncology sedation trial (POST): A double-blind randomized study. ( Barr, RD; Buckley, N; Korz, L; Lappan, J; Nagel, K; Willan, AR, 2008) |
| "Seizures occurred in two adolescents approximately six hours after sedation with propofol for bone marrow biopsy." | 3.68 | Delayed seizures following sedation with propofol. ( Fernandez, CV; Finley, GA; MacManus, B; Retallick, R; Sampson, SE, 1993) |
| "The 5-year survival for pediatric acute lymphoblastic leukemia (ALL) is greater than 90%." | 1.56 | Sedation practices in pediatric patients with acute lymphoblastic leukemia. ( Davis, PJ; Noll, RB; Nugent, BD; Tersak, JM, 2020) |
| " We retrieved the following: demographics; diagnosis; chemotherapy phase; use of corticosteroids; induction dosage of propofol, fentanyl and/or ketamine; and the type of procedure." | 1.48 | Induction Dosage of Propofol for Repeated Sedations in Children With Hematological Disorders. ( Beltrama, V; Bosatra, M; Ciceri, V; Moretto, A; Pesenti, A; Rota, M; Scaravilli, V; Zanella, A, 2018) |
| "This study explored the sedative and analgesic effects of fentanyl combined with propofol via an intrathecal chemotherapy injection for acute leukemia (acute lymphocytic leukemia or acute myelocytic leukemia) among children, to relieve pain and difficulty during intrathecal injection, improve treatment compliance, increase the success rate of single puncture, and reduce procedure failure, with the aim of developing a painless procedure for children with acute leukemia." | 1.42 | Rapid sedation induced by fentanyl combined with propofol via an intrathecal chemotherapy injection for leukemia in children. ( Lao, JQ; Tian, X; Tian, YY; Wang, HP; Wei, HY; Yang, YH, 2015) |
| "To strongly improve comfort and quality of life of children with ALL and reduce the risk of TLP+ mainly at diagnosis, we recommend performing the lumbar punctures under analgo-sedation because it is a safe and effective procedure." | 1.40 | Safe lumbar puncture under analgo-sedation in children with acute lymphoblastic leukemia. ( Attinà , G; Chiaretti, A; Coccia, P; Maurizi, P; Riccardi, R; Rizzo, D; Ruggiero, A; Russo, I, 2014) |
| "The immune system of children with acute lymphoblastic leukemia (ALL) is affected by both the underlying disease and the chemotherapy." | 1.39 | The effects of propofol and ketamine on the cytokine levels of children with acute lymphoblastic leukemia. ( Bertolizio, G; Biondi, A; D'Amico, G; Dander, E; Ingelmo, PM; Jankovic, M; Sahillioglu, E; Somaini, M; Stucchi, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Wright, ML | 1 |
| O'Brien, SH | 1 |
| Schloss, B | 1 |
| Stanek, JR | 1 |
| Reed, S | 1 |
| Nugent, BD | 1 |
| Davis, PJ | 1 |
| Noll, RB | 1 |
| Tersak, JM | 1 |
| Waters, TW | 1 |
| Dickens, DS | 1 |
| Johnson, LM | 1 |
| Frader, J | 1 |
| Wolfe, J | 1 |
| Baker, JN | 1 |
| Anghelescu, DL | 1 |
| Lantos, JD | 1 |
| Moretto, A | 1 |
| Zanella, A | 1 |
| Ciceri, V | 1 |
| Rota, M | 1 |
| Scaravilli, V | 1 |
| Beltrama, V | 1 |
| Bosatra, M | 1 |
| Pesenti, A | 1 |
| Bertolizio, G | 2 |
| Stucchi, R | 1 |
| Sahillioglu, E | 1 |
| Somaini, M | 1 |
| Dander, E | 1 |
| Biondi, A | 1 |
| Jankovic, M | 1 |
| D'Amico, G | 1 |
| Ingelmo, PM | 1 |
| Yuce, HH | 1 |
| Altay, N | 1 |
| Karahan, MA | 1 |
| Ocal, F | 1 |
| Ingelmo, P | 1 |
| Whitlow, PG | 1 |
| Saboda, K | 1 |
| Roe, DJ | 1 |
| Bazzell, S | 1 |
| Wilson, C | 1 |
| Tian, X | 1 |
| Yang, YH | 1 |
| Wei, HY | 1 |
| Lao, JQ | 1 |
| Wang, HP | 1 |
| Tian, YY | 1 |
| Nagel, K | 1 |
| Willan, AR | 1 |
| Lappan, J | 1 |
| Korz, L | 1 |
| Buckley, N | 1 |
| Barr, RD | 1 |
| Chiaretti, A | 2 |
| Ruggiero, A | 2 |
| Barone, G | 1 |
| Antonelli, A | 1 |
| Lazzareschi, I | 1 |
| Genovese, O | 1 |
| Paiano, S | 1 |
| Sammartino, M | 1 |
| Maurizi, P | 2 |
| Riccardi, R | 2 |
| Russo, I | 1 |
| Rizzo, D | 1 |
| Coccia, P | 1 |
| Attinà , G | 1 |
| Burgoyne, LL | 1 |
| Hoffer, FA | 1 |
| de Armendi, AJ | 1 |
| Finley, GA | 1 |
| MacManus, B | 1 |
| Sampson, SE | 1 |
| Fernandez, CV | 1 |
| Retallick, R | 1 |
| Gozal, D | 1 |
| Gozal, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090] | Phase 3 | 30 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for propofol and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Topical analgesia treats pain and decreases propofol use during lumbar punctures in a randomized pediatric leukemia trial.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Cross-Over | 2015 |
Pediatric oncology sedation trial (POST): A double-blind randomized study.
Topics: Adolescent; Antiemetics; Antineoplastic Agents; Biopsy, Needle; Bone Marrow Examination; Child; Chil | 2008 |
14 other studies available for propofol and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Sedation Practices for Lumbar Punctures in Patients With Acute Lymphoblastic Leukemia: A Multicenter Retrospective Study Using Pediatric Health Information Systems.
Topics: Acute Disease; Adolescent; Anesthesia; Anesthetics, Local; Child; Child, Preschool; Conscious Sedati | 2022 |
Sedation practices in pediatric patients with acute lymphoblastic leukemia.
Topics: Central Nervous System; Child; Follow-Up Studies; Humans; Hypnotics and Sedatives; Neurocognitive Di | 2020 |
Reducing sedated lumbar punctures in pediatric patients with acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Child; COVID-19; Female; Humans; Hypnotics and Sedatives; Male; Pain Management; | 2021 |
Palliative Sedation With Propofol for an Adolescent With a DNR Order.
Topics: Adolescent; Deep Sedation; Ethics Consultation; Ethics, Medical; Female; Humans; Interdisciplinary C | 2017 |
Induction Dosage of Propofol for Repeated Sedations in Children With Hematological Disorders.
Topics: Child; Child, Preschool; Deep Sedation; Female; Humans; Leukemia, Myeloid, Acute; Lymphoma; Male; Pr | 2018 |
The effects of propofol and ketamine on the cytokine levels of children with acute lymphoblastic leukemia.
Topics: Anesthetics; Child, Preschool; Cytokines; Female; Humans; Infant; Infant, Newborn; Ketamine; Male; P | 2013 |
Propofol and additives in studies evaluating inflammatory responses.
Topics: Anesthetics; Cytokines; Female; Humans; Ketamine; Male; Precursor Cell Lymphoblastic Leukemia-Lympho | 2015 |
In reply: Propofol and additives in studies evaluating inflammatory responses.
Topics: Anesthetics; Cytokines; Female; Humans; Ketamine; Male; Precursor Cell Lymphoblastic Leukemia-Lympho | 2015 |
Rapid sedation induced by fentanyl combined with propofol via an intrathecal chemotherapy injection for leukemia in children.
Topics: Adolescent; Antineoplastic Agents; Blood Pressure; Case-Control Studies; Child; Child, Preschool; De | 2015 |
Propofol/alfentanil and propofol/ketamine procedural sedation in children with acute lymphoblastic leukaemia: safety, efficacy and their correlation with pain neuromediator expression.
Topics: Adolescent; Alfentanil; Anxiety; Child; Child, Preschool; Conscious Sedation; Cross-Over Studies; Dr | 2010 |
Safe lumbar puncture under analgo-sedation in children with acute lymphoblastic leukemia.
Topics: Adolescent; Central Nervous System; Child; Child, Preschool; Deep Sedation; Female; Humans; Infant; | 2014 |
Anesthesia for a patient with bilateral undrained pneumothoraces.
Topics: Anesthesia, General; Anesthetics, Intravenous; Bone Marrow; Child, Preschool; Female; Fentanyl; Huma | 2006 |
Delayed seizures following sedation with propofol.
Topics: Adolescent; Anesthesia Recovery Period; Bone Marrow Examination; Child; Conscious Sedation; Female; | 1993 |
Behavior disturbances with repeated propofol sedation in a child.
Topics: Child Behavior Disorders; Female; Humans; Hypnotics and Sedatives; Infant; Precursor Cell Lymphoblas | 1999 |