propofol has been researched along with Porphyrias in 22 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "On two occasions a patient suffering from acute intermittent porphyria (AIP) was anaesthetized with propofol as the sole agent." | 7.67 | Safe use of propofol in a patient with acute intermittent porphyria. ( Fuith, LC; Hetzel, H; Mitterschiffthaler, G; Theiner, A, 1988) |
| "A case is presented of the use of a propofol infusion for anaesthesia in a patient with known variegate porphyria." | 7.67 | Is propofol a safe agent in porphyria? ( Hodkinson, BP; Weir, PM, 1988) |
| "On two occasions a patient suffering from acute intermittent porphyria (AIP) was anaesthetized with propofol as the sole agent." | 3.67 | Safe use of propofol in a patient with acute intermittent porphyria. ( Fuith, LC; Hetzel, H; Mitterschiffthaler, G; Theiner, A, 1988) |
| "A case is presented of the use of a propofol infusion for anaesthesia in a patient with known variegate porphyria." | 3.67 | Is propofol a safe agent in porphyria? ( Hodkinson, BP; Weir, PM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 11 (50.00) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Böhrer, H | 1 |
| Schmidt, H | 1 |
| Tidmarsh, MD | 1 |
| Gorchein, A | 1 |
| Mamet, R | 1 |
| Schoenfeld, N | 1 |
| Sarantopoulos, CD | 1 |
| Bratanow, NC | 1 |
| Stowe, DF | 1 |
| Kampine, JP | 1 |
| Harrison, JC | 1 |
| McAuley, FT | 1 |
| Tidmarsh, MA | 1 |
| Baigent, DF | 1 |
| Kantor, G | 1 |
| Rolbin, SH | 1 |
| Meissner, PN | 1 |
| Harrison, GG | 1 |
| Hift, RJ | 1 |
| Christian, AS | 1 |
| Hughes, PJ | 1 |
| Parr, MJ | 1 |
| Hayden-Smith, J | 1 |
| Blanloeil, Y | 1 |
| Deybach, JC | 1 |
| Montange, F | 1 |
| Thomas, B | 1 |
| Truffa-Bachi, J | 1 |
| McLouglin, C | 1 |
| McNeill, MJ | 1 |
| Parikh, RK | 1 |
| Moore, MR | 1 |
| Malthe, R | 1 |
| Fouilloux, P | 1 |
| Mitterschiffthaler, G | 1 |
| Theiner, A | 1 |
| Hetzel, H | 1 |
| Fuith, LC | 1 |
| Cooper, R | 1 |
| Richard, T | 1 |
| Haberer, JP | 1 |
| Weir, PM | 1 |
| Hodkinson, BP | 1 |
1 trial available for propofol and Porphyrias
| Article | Year |
|---|---|
Propofol as an i.v. anaesthetic induction agent in variegate porphyria.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Humans; Liver Diseases; Middle Aged; Porphyrias; P | 1991 |
21 other studies available for propofol and Porphyrias
| Article | Year |
|---|---|
Anaesthesia for the porphyric patient.
Topics: Anesthesia; Anesthesia, Conduction; Humans; Porphyrias; Propofol | 1993 |
Porphyria, propofol and rats.
Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Humans; Hypnotics and Sedatives; Porphyri | 1996 |
Porphyria, propofol and rats.
Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Humans; Hypnotics and Sedatives; Porphyri | 1996 |
A reliable diagnosis of porphyria should precede any conclusion concerning the safety of a drug in porphyria.
Topics: Anesthetics, Intravenous; Humans; Porphyrias; Propofol | 1999 |
Uneventful propofol anesthesia in a patient with coexisting hereditary coproporphyria and hereditary angioneurotic edema.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Angioedema; Arthroscopy; Coproporphyrins; | 2000 |
Propofol for sedation in intensive care in a patient with an acute porphyric attack.
Topics: Acute Disease; Adult; Female; Humans; Intensive Care Units; Porphyrias; Porphyrins; Propofol | 1992 |
Propofol in acute intermittent porphyria.
Topics: Acute Disease; Adult; Anesthesia, Intravenous; Female; Humans; Porphyrias; Propofol | 1992 |
Acute intermittent porphyria and caesarean delivery.
Topics: Acute Disease; Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Cesarean Section; Female; Hu | 1992 |
Safe use of propofol in a child with acute intermittent porphyria.
Topics: Acute Disease; Anesthesia, General; Child; Female; Humans; Porphyrias; Propofol | 1991 |
Propofol in acute porphyrias.
Topics: Acute Disease; Adult; Anesthesia, General; Coproporphyrins; Female; Humans; Porphyrias; Postoperativ | 1990 |
Propofol, porphyria and epilepsy.
Topics: Adult; Anesthesia, General; Epilepsy; Female; Humans; Porphyrias; Porphyrins; Propofol | 1990 |
[Propofol (Diprivan) and hepatic porphyria].
Topics: Animals; Chick Embryo; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Liver Diseases; Po | 1989 |
[Use of propofol in a patient with acute intermittent porphyria].
Topics: Acute Disease; Aged; Anesthesia, General; Female; Humans; Porphyrias; Propofol | 1989 |
Use of propofol in a patient with porphyria.
Topics: Anesthesia, General; Anesthetics; Female; Humans; Liver Diseases; Middle Aged; Phenols; Porphyrias; | 1989 |
Propofol in acute porphyria.
Topics: Acute Disease; Anesthetics; Humans; Phenols; Porphyrias; Propofol | 1989 |
Porphyria and propofol.
Topics: Anesthesia, Intravenous; Anesthetics; Humans; Phenols; Porphyrias; Propofol | 1989 |
[Use of propofol in a patient with acute intermittent porphyria].
Topics: Anesthetics; Female; Humans; Middle Aged; Phenols; Porphyrias; Propofol | 1989 |
Safe use of propofol in a patient with acute intermittent porphyria.
Topics: Acute Disease; Adult; Anesthesia, Intravenous; Anesthetics; Female; Humans; Phenols; Porphyrias; Pro | 1988 |
Anaesthesia for porphyria using propofol.
Topics: Anesthesia, Intravenous; Anesthetics; Female; Humans; Middle Aged; Phenols; Porphyrias; Propofol | 1988 |
[Use of propofol (Diprivan) in a patient with intermittent porphyria].
Topics: Adult; Anesthesia, General; Anesthetics; Female; Humans; In Vitro Techniques; Phenols; Porphyrias; P | 1988 |
Is propofol a safe agent in porphyria?
Topics: Adult; Anesthesia, Intravenous; Anesthetics; Forearm Injuries; Humans; Liver Diseases; Male; Phenols | 1988 |