propofol has been researched along with Porphyrias, Hepatic in 6 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Porphyrias, Hepatic: A group of metabolic diseases due to deficiency of one of a number of LIVER enzymes in the biosynthetic pathway of HEME. They are characterized by the accumulation and increased excretion of PORPHYRINS or its precursors. Clinical features include neurological symptoms (PORPHYRIA, ACUTE INTERMITTENT), cutaneous lesions due to photosensitivity (PORPHYRIA CUTANEA TARDA), or both (HEREDITARY COPROPORPHYRIA). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol may be used without any restriction in all cases of asymptomatic hepatic porphyria, as a bolus injection for induction and maintenance of anaesthesia and as a continuous infusion to produce anaesthesia of short and medium duration." | 3.69 | [Acute hepatic porphyria and Diprivan]. ( Blanloeil, Y, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Böhrer, H | 2 |
| Schmidt, H | 2 |
| Martin, E | 1 |
| Lux, R | 1 |
| Bolsen, K | 1 |
| Goerz, G | 1 |
| Blanloeil, Y | 1 |
| Motsch, J | 1 |
| Kasraie, N | 1 |
| Cousins, TB | 1 |
| Bichel, T | 1 |
| Joris, J | 1 |
| Jacquet, N | 1 |
| Lamy, M | 1 |
| Gorchein, A | 1 |
1 review available for propofol and Porphyrias, Hepatic
| Article | Year |
|---|---|
Total intravenous anesthesia in South-African genetic porphyria (variegate porphyria).
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Female; Humans; Liver Neoplasms; Porphyrias, He | 1993 |
5 other studies available for propofol and Porphyrias, Hepatic
| Article | Year |
|---|---|
Testing the porphyrinogenicity of propofol in a primed rat model.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Aminolevulinic Acid; Anesthetics, Intravenous | 1995 |
[Acute hepatic porphyria and Diprivan].
Topics: Anesthesia, Intravenous; Contraindications; Humans; Porphyrias, Hepatic; Porphyrins; Propofol | 1994 |
Propofol and the patient with hereditary coproporphyria.
Topics: Humans; Porphyrias, Hepatic; Propofol | 1994 |
Propofol and the patient with hereditary coproporphyria.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, General; Female; Humans; Porphyrias, Hepatic; Pro | 1993 |
Porphyria, propofol and rats.
Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Humans; Hypnotics and Sedatives; Porphyri | 1996 |