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propofol and Porphyria

propofol has been researched along with Porphyria in 22 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"On two occasions a patient suffering from acute intermittent porphyria (AIP) was anaesthetized with propofol as the sole agent."7.67Safe use of propofol in a patient with acute intermittent porphyria. ( Fuith, LC; Hetzel, H; Mitterschiffthaler, G; Theiner, A, 1988)
"A case is presented of the use of a propofol infusion for anaesthesia in a patient with known variegate porphyria."7.67Is propofol a safe agent in porphyria? ( Hodkinson, BP; Weir, PM, 1988)
"On two occasions a patient suffering from acute intermittent porphyria (AIP) was anaesthetized with propofol as the sole agent."3.67Safe use of propofol in a patient with acute intermittent porphyria. ( Fuith, LC; Hetzel, H; Mitterschiffthaler, G; Theiner, A, 1988)
"A case is presented of the use of a propofol infusion for anaesthesia in a patient with known variegate porphyria."3.67Is propofol a safe agent in porphyria? ( Hodkinson, BP; Weir, PM, 1988)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199010 (45.45)18.7374
1990's11 (50.00)18.2507
2000's1 (4.55)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Böhrer, H1
Schmidt, H1
Tidmarsh, MD1
Gorchein, A1
Mamet, R1
Schoenfeld, N1
Sarantopoulos, CD1
Bratanow, NC1
Stowe, DF1
Kampine, JP1
Harrison, JC1
McAuley, FT1
Tidmarsh, MA1
Baigent, DF1
Kantor, G1
Rolbin, SH1
Meissner, PN1
Harrison, GG1
Hift, RJ1
Christian, AS1
Hughes, PJ1
Parr, MJ1
Hayden-Smith, J1
Blanloeil, Y1
Deybach, JC1
Montange, F1
Thomas, B1
Truffa-Bachi, J1
McLouglin, C1
McNeill, MJ1
Parikh, RK1
Moore, MR1
Malthe, R1
Fouilloux, P1
Mitterschiffthaler, G1
Theiner, A1
Hetzel, H1
Fuith, LC1
Cooper, R1
Richard, T1
Haberer, JP1
Weir, PM1
Hodkinson, BP1

Trials

1 trial available for propofol and Porphyria

ArticleYear
Propofol as an i.v. anaesthetic induction agent in variegate porphyria.
    British journal of anaesthesia, 1991, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Humans; Liver Diseases; Middle Aged; Porphyrias; P

1991

Other Studies

21 other studies available for propofol and Porphyria

ArticleYear
Anaesthesia for the porphyric patient.
    Anaesthesia, 1993, Volume: 48, Issue:10

    Topics: Anesthesia; Anesthesia, Conduction; Humans; Porphyrias; Propofol

1993
Porphyria, propofol and rats.
    British journal of anaesthesia, 1996, Volume: 76, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Humans; Hypnotics and Sedatives; Porphyri

1996
Porphyria, propofol and rats.
    British journal of anaesthesia, 1996, Volume: 76, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Humans; Hypnotics and Sedatives; Porphyri

1996
A reliable diagnosis of porphyria should precede any conclusion concerning the safety of a drug in porphyria.
    Anesthesiology, 1999, Volume: 91, Issue:2

    Topics: Anesthetics, Intravenous; Humans; Porphyrias; Propofol

1999
Uneventful propofol anesthesia in a patient with coexisting hereditary coproporphyria and hereditary angioneurotic edema.
    Anesthesiology, 2000, Volume: 92, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Angioedema; Arthroscopy; Coproporphyrins;

2000
Propofol for sedation in intensive care in a patient with an acute porphyric attack.
    Anaesthesia, 1992, Volume: 47, Issue:4

    Topics: Acute Disease; Adult; Female; Humans; Intensive Care Units; Porphyrias; Porphyrins; Propofol

1992
Propofol in acute intermittent porphyria.
    British journal of anaesthesia, 1992, Volume: 68, Issue:2

    Topics: Acute Disease; Adult; Anesthesia, Intravenous; Female; Humans; Porphyrias; Propofol

1992
Acute intermittent porphyria and caesarean delivery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:3

    Topics: Acute Disease; Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Cesarean Section; Female; Hu

1992
Safe use of propofol in a child with acute intermittent porphyria.
    Anaesthesia, 1991, Volume: 46, Issue:5

    Topics: Acute Disease; Anesthesia, General; Child; Female; Humans; Porphyrias; Propofol

1991
Propofol in acute porphyrias.
    Anaesthesia, 1990, Volume: 45, Issue:5

    Topics: Acute Disease; Adult; Anesthesia, General; Coproporphyrins; Female; Humans; Porphyrias; Postoperativ

1990
Propofol, porphyria and epilepsy.
    Anaesthesia, 1990, Volume: 45, Issue:7

    Topics: Adult; Anesthesia, General; Epilepsy; Female; Humans; Porphyrias; Porphyrins; Propofol

1990
[Propofol (Diprivan) and hepatic porphyria].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Animals; Chick Embryo; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Liver Diseases; Po

1989
[Use of propofol in a patient with acute intermittent porphyria].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:6

    Topics: Acute Disease; Aged; Anesthesia, General; Female; Humans; Porphyrias; Propofol

1989
Use of propofol in a patient with porphyria.
    British journal of anaesthesia, 1989, Volume: 62, Issue:1

    Topics: Anesthesia, General; Anesthetics; Female; Humans; Liver Diseases; Middle Aged; Phenols; Porphyrias;

1989
Propofol in acute porphyria.
    Anaesthesia, 1989, Volume: 44, Issue:6

    Topics: Acute Disease; Anesthetics; Humans; Phenols; Porphyrias; Propofol

1989
Porphyria and propofol.
    Anaesthesia, 1989, Volume: 44, Issue:7

    Topics: Anesthesia, Intravenous; Anesthetics; Humans; Phenols; Porphyrias; Propofol

1989
[Use of propofol in a patient with acute intermittent porphyria].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:3

    Topics: Anesthetics; Female; Humans; Middle Aged; Phenols; Porphyrias; Propofol

1989
Safe use of propofol in a patient with acute intermittent porphyria.
    British journal of anaesthesia, 1988, Volume: 60, Issue:1

    Topics: Acute Disease; Adult; Anesthesia, Intravenous; Anesthetics; Female; Humans; Phenols; Porphyrias; Pro

1988
Anaesthesia for porphyria using propofol.
    Anaesthesia, 1988, Volume: 43, Issue:7

    Topics: Anesthesia, Intravenous; Anesthetics; Female; Humans; Middle Aged; Phenols; Porphyrias; Propofol

1988
[Use of propofol (Diprivan) in a patient with intermittent porphyria].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:5

    Topics: Adult; Anesthesia, General; Anesthetics; Female; Humans; In Vitro Techniques; Phenols; Porphyrias; P

1988
Is propofol a safe agent in porphyria?
    Anaesthesia, 1988, Volume: 43, Issue:12

    Topics: Adult; Anesthesia, Intravenous; Anesthetics; Forearm Injuries; Humans; Liver Diseases; Male; Phenols

1988