Page last updated: 2024-11-03

propofol and Pneumonia

propofol has been researched along with Pneumonia in 11 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"To determine the effects of propofol and sevoflurane on cytokine levels in children with community-acquired pneumonia undergoing flexible fibreoptic bronchoscopy (FFB)."5.22Effects of different anaesthetics on cytokine levels in children with community-acquired pneumonia undergoing flexible fibreoptic bronchoscopy. ( Chen, L; Cheng, J; Wang, YL, 2016)
"Secondary outcomes included lung inflammation defined as changes in other biomarkers and postoperative pulmonary complications."3.11Anesthetics to Prevent Lung Injury in Cardiac Surgery: A Randomized Controlled Trial. ( Baedorf Kassis, EN; Banner-Goodspeed, VM; Beydoun, N; Bose, S; Gasangwa, DV; Gosling, AF; Khabbaz, K; Kumaresan, A; Mahmood, FU; Mueller, AL; Novack, V; O'Gara, BP; Patxot, M; Sagy, I; Shaefi, S; Shapeton, A; Spear, K; Subramaniam, B; Talmor, DS, 2022)
"Propofol has anti-inflammatory and immunomodulatory properties which may attenuate this response."2.73Effects of propofol on pulmonary inflammatory response and dysfunction induced by cardiopulmonary bypass. ( An, K; Huang, W; Huang, X; Shu, H; Wang, C; Xu, K; Xu, M; Yang, L, 2008)
"Propofol was the most common adjunct agent, with dexmedetomidine and antipsychotics also used."1.42Multicenter evaluation of pharmacologic management and outcomes associated with severe resistant alcohol withdrawal. ( Benedict, NJ; Kane-Gill, SL; Wong, A, 2015)
"Nevertheless, severe hypoxemia is an accepted contraindication to FOB in nonintubated patients."1.31Bronchoscopy with bronchoalveolar lavage via the laryngeal mask airway in high-risk hypoxemic immunosuppressed patients. ( Cardinaud, JP; Favier, JC; Gbikpi-Benissan, G; Gruson, D; Hilbert, G; Portel, L; Valentino, R; Vargas, F, 2001)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
O'Gara, BP1
Shaefi, S1
Gasangwa, DV1
Patxot, M1
Beydoun, N1
Mueller, AL1
Sagy, I1
Novack, V1
Banner-Goodspeed, VM1
Kumaresan, A1
Shapeton, A1
Spear, K1
Bose, S1
Baedorf Kassis, EN1
Gosling, AF1
Mahmood, FU1
Khabbaz, K1
Subramaniam, B1
Talmor, DS1
Zhang, GH1
Wang, W1
Luo, G1
Zhu, G1
Yuan, D1
Yao, W1
Chi, X1
Hei, Z1
Wong, A1
Benedict, NJ1
Kane-Gill, SL1
Stewart, R1
Perez, R1
Musial, B1
Lukens, C1
Adjepong, YA1
Manthous, CA1
Chen, L1
Cheng, J1
Wang, YL1
Kellner, P1
Müller, M1
Piegeler, T1
Eugster, P1
Booy, C1
Schläpfer, M1
Beck-Schimmer, B1
An, K1
Shu, H1
Huang, W1
Huang, X1
Xu, M1
Yang, L1
Xu, K1
Wang, C1
Pelter, MM1
Carey, MG1
Gómez Ayechu, M1
Castañeda Pascual, M1
Zaballos Barcala, N1
Unzué Rico, P1
Hilbert, G1
Gruson, D1
Vargas, F1
Valentino, R1
Favier, JC1
Portel, L1
Gbikpi-Benissan, G1
Cardinaud, JP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sevoflurane Sedation: A Potentially Promising Immunomodulation in Patients With Septic Shock[NCT03643367]Phase 2153 participants (Anticipated)Interventional2025-01-31Not yet recruiting
AnaConDa-therapy in COVID-19 Patients[NCT05586126]42 participants (Actual)Observational2020-10-01Terminated (stopped due to Concerns about possible association between drug and increased ICU mortality)
A Randomized Pilot Clinical Trial of the Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction of Sevoflurane in Patient's Whit ARDS Secondary to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2)[NCT04998253]Early Phase 124 participants (Actual)Interventional2020-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for propofol and Pneumonia

ArticleYear
Anesthetics to Prevent Lung Injury in Cardiac Surgery: A Randomized Controlled Trial.
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:10

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Biomarkers; Cardiac Surgical Procedures; H

2022
Effects of different anaesthetics on cytokine levels in children with community-acquired pneumonia undergoing flexible fibreoptic bronchoscopy.
    The Journal of international medical research, 2016, Volume: 44, Issue:3

    Topics: Anesthetics; Bronchoscopy; Child; Child, Preschool; Community-Acquired Infections; Cytokines; Demogr

2016
Effects of propofol on pulmonary inflammatory response and dysfunction induced by cardiopulmonary bypass.
    Anaesthesia, 2008, Volume: 63, Issue:11

    Topics: Aged; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Cardiopulmonary Bypass; Fem

2008

Other Studies

8 other studies available for propofol and Pneumonia

ArticleYear
Effects of sevoflurane and propofol on the development of pneumonia after esophagectomy: a retrospective cohort study.
    BMC anesthesiology, 2017, Dec-04, Volume: 17, Issue:1

    Topics: Aged; Anesthetics, Inhalation; Cohort Studies; Esophageal Neoplasms; Esophagectomy; Female; Hospital

2017
Propofol alleviates acute lung injury following orthotopic autologous liver transplantation in rats via inhibition of the NADPH oxidase pathway.
    Molecular medicine reports, 2015, Volume: 11, Issue:3

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Hypnotics and Sedatives; Liver Transplantation;

2015
Multicenter evaluation of pharmacologic management and outcomes associated with severe resistant alcohol withdrawal.
    Journal of critical care, 2015, Volume: 30, Issue:2

    Topics: Adult; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Antipsychotic Agents; Benzodiazepin

2015
Outcomes of Patients with Alcohol Withdrawal Syndrome Treated with High-Dose Sedatives and Deferred Intubation.
    Annals of the American Thoracic Society, 2016, Volume: 13, Issue:2

    Topics: Adult; Alcohol Withdrawal Seizures; APACHE; Central Nervous System Depressants; Cohort Studies; Crit

2016
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:1

    Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age

2017
Long QT syndrome.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2006, Volume: 15, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Electrocardiography; Female; Humans; Intubation, Intratracheal; Long

2006
[Anesthetic implications of Swyer-James syndrome].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:10

    Topics: Adolescent; Anesthesia, Intravenous; Asthma; Atracurium; Atropine; Bronchiectasis; Drainage; Fentany

2006
Bronchoscopy with bronchoalveolar lavage via the laryngeal mask airway in high-risk hypoxemic immunosuppressed patients.
    Critical care medicine, 2001, Volume: 29, Issue:2

    Topics: Aged; Anesthetics, Intravenous; Blood Gas Analysis; Bronchoalveolar Lavage; Bronchoscopy; Contraindi

2001