Page last updated: 2024-11-03

propofol and Pheochromocytoma

propofol has been researched along with Pheochromocytoma in 22 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"This study aimed to explore the efficacy of propofol to treat malignant pheochromocytoma (PCC) in vitro and in vivo."7.88Propofol Prevents the Progression of Malignant Pheochromocytoma In Vitro and In Vivo. ( Wang, H; Yan, C; Zhang, A; Zhang, S, 2018)
"In two patients, pheochromocytoma resection was performed under propofol/fentanyl anesthesia, while bispectral index (BIS) monitoring and blood volume measurement using pulse spectrophotometry were done."7.73[Anesthetic management with propofol for pheochromocytoma resection under monitoring of bispectral index and blood volume]. ( Ishida, K; Matsumoto, M; Morimoto, Y; Orita, H; Sakabe, T; Tsuruta, S; Utada, K, 2006)
"In three patients undergoing pheochromocytoma resection under propofol/fentanyl anesthesia, bispectral index (BIS) was monitored for assessment of hypnotic effect."7.72[Anesthetic management with propofol during pheochromocytoma resection under bispectral index monitoring]. ( Ishida, K; Morimoto, Y; Nakamura, M; Sakabe, T; Utada, K; Yamashita, S, 2004)
"This study aimed to explore the efficacy of propofol to treat malignant pheochromocytoma (PCC) in vitro and in vivo."3.88Propofol Prevents the Progression of Malignant Pheochromocytoma In Vitro and In Vivo. ( Wang, H; Yan, C; Zhang, A; Zhang, S, 2018)
"In two patients, pheochromocytoma resection was performed under propofol/fentanyl anesthesia, while bispectral index (BIS) monitoring and blood volume measurement using pulse spectrophotometry were done."3.73[Anesthetic management with propofol for pheochromocytoma resection under monitoring of bispectral index and blood volume]. ( Ishida, K; Matsumoto, M; Morimoto, Y; Orita, H; Sakabe, T; Tsuruta, S; Utada, K, 2006)
"Halothane and isoflurane enhanced amyloid beta oligomerization rates and pheochromocytoma cytotoxicity in vitro through a preference for binding small oligomeric species."3.72Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity. ( Carnini, A; Eckenhoff, MF; Eckenhoff, RG; Johansson, JS; Kang, B; Keller, JM; Pidikiti, R; Wei, H; Wei, W, 2004)
" Anesthesia was induced with propofol and vecuronium, and maintained with intermittent fentanyl and sevoflurane in nitrous oxide and oxygen."3.72[Anesthetic management for removal of pheochromocytoma in a patient after repair of tetralogy of Fallot]. ( Hamakawa, T; Kawano, T; Maruta, T; Suzuki, N; Takasaki, M; Yano, T, 2004)
"In three patients undergoing pheochromocytoma resection under propofol/fentanyl anesthesia, bispectral index (BIS) was monitored for assessment of hypnotic effect."3.72[Anesthetic management with propofol during pheochromocytoma resection under bispectral index monitoring]. ( Ishida, K; Morimoto, Y; Nakamura, M; Sakabe, T; Utada, K; Yamashita, S, 2004)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (22.73)18.2507
2000's15 (68.18)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watanabe, T1
Hiraoka, H1
Araki, T1
Nagano, D1
Aomori, T1
Nakamura, T1
Yamamoto, K1
Baba, H1
Wang, H1
Zhang, S1
Zhang, A1
Yan, C1
Hegde, HV1
Puri, GD1
Kumar, B1
Behera, A1
Morishima, T1
Sobue, K1
Arima, H1
Tanaka, S1
So, M1
Ando, H1
Katsuya, H1
Eckenhoff, RG1
Johansson, JS1
Wei, H1
Carnini, A1
Kang, B1
Wei, W1
Pidikiti, R1
Keller, JM1
Eckenhoff, MF1
Shafiq, B1
Zuckerman, RL1
Queale, WS1
Cosgarea, AJ1
Ng, JM1
Yano, T1
Maruta, T1
Kawano, T1
Hamakawa, T1
Suzuki, N1
Takasaki, M1
Ando, T1
Goto, R1
Ohnishi, H1
Ishida, M1
Obara, H1
Cruz, P1
Varela, A1
Carmona, P1
Alonso, A1
Piñeiro, P1
García de Lucas, E1
Utada, K2
Ishida, K2
Nakamura, M1
Morimoto, Y2
Yamashita, S1
Sakabe, T2
Orita, H1
Tsuruta, S1
Matsumoto, M1
Hack, H1
Maddali, MM1
Matreja, PV1
Isik, A1
Taydas, E1
Ulukaya, S1
Balcioglu, T1
Aydin, U1
Kilic, M1
Rassam, S1
Schüttler, J1
Westhofen, P1
Kania, U1
Ihmsen, H1
Kammerecker, S1
Hirner, A1
Kreienmeyer, J1
Beisty-Chueca, JC1
Rupérez-Gil, A1
Alagón-Abad, MC1
García Retegui, E1
Roa-Martínez, I1
Sahin, A1
Erçelen, O1
Aypar, U1
Erbengi, A1
Kimura, M1
Nakagawa, I1
Hamada, H1
Uesugi, F1
Sakai, A1
Strebel, S1
Scheidegger, D1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Association Between Changes in Cerebral Gray Matter Volume and Postoperative Cognitive Dysfunction in Elderly Patients Following Sevoflurane Anesthesia (POCD-MRI)[NCT02045004]100 participants (Actual)Observational2015-07-14Completed
Release of Serum Neurofilament Light (NFL), Biomarker of Neuronal Injury, in Surgery Under General Anaesthesia (GA) Compared to Surgery With Hypno-analgesia (Hyp): A Prospective, Non-inferiority Study[NCT04500236]100 participants (Anticipated)Interventional2020-09-01Recruiting
Evaluation of Stress Hormone Concentration During the Resection of Pheochromocytoma. Comparison of Surgeon - Anesthesiologist - Patient[NCT00948181]8 participants (Anticipated)Observational2009-06-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for propofol and Pheochromocytoma

ArticleYear
[Quantitative assessment of catecholamine secretion as a rational principle of anesthesia management in pheochromocytoma surgery].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1995, Volume: 30, Issue:6

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Alfentanil; Anesthesia, General; Anesthesia, Intravenous

1995

Other Studies

21 other studies available for propofol and Pheochromocytoma

ArticleYear
Significant decreases in blood propofol concentrations during adrenalectomy for phaeochromocytoma.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:10

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Anesthesia; Anesthetics, Intravenous; Arterial

2017
Propofol Prevents the Progression of Malignant Pheochromocytoma In Vitro and In Vivo.
    DNA and cell biology, 2018, Volume: 37, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Cycle Check

2018
Bi-spectral index guided closed-loop anaesthesia delivery system (CLADS) in pheochromocytoma.
    Journal of clinical monitoring and computing, 2009, Volume: 23, Issue:4

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Anesthesia, Closed-Circuit; Anesthesia, General; B

2009
Profound pain due to propofol injection triggered myocardial ischemia in a patient with a suspected pheochromocytoma.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Anesthetics, Intravenous; Electrocardiography; Humans; Male; Myocard

2003
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy

2004
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy

2004
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy

2004
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy

2004
Hypertensive crisis secondary to pheochromocytoma during routine knee surgery.
    The journal of knee surgery, 2004, Volume: 17, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Anesthetics, Intravenous; Arthroscopy; Fentanyl; Humans; Hypertensio

2004
Desflurane and remifentanil use during resection of a cardiac pheochromocytoma.
    Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:5

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Cardiopulmonary Bypass; Cathet

2004
[Anesthetic management for removal of pheochromocytoma in a patient after repair of tetralogy of Fallot].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:11

    Topics: Adrenal Gland Neoplasms; Anesthesia; Female; Fentanyl; Humans; Magnesium Sulfate; Methyl Ethers; Mid

2004
[Anesthetic management for a patient of myotonic dystrophy with pheochromocytoma].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:11

    Topics: Adrenal Gland Neoplasms; Anesthesia, Epidural; Humans; Laparoscopy; Male; Middle Aged; Myotonic Dyst

2004
[General intravenous anesthesia with remifentanil and propofol for laparoscopic adrenalectomy in 2 patients with pheochromocytomas].
    Revista espanola de anestesiologia y reanimacion, 2004, Volume: 51, Issue:9

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous;

2004
[Anesthetic management with propofol during pheochromocytoma resection under bispectral index monitoring].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:12

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Ch

2004
[Anesthetic management with propofol for pheochromocytoma resection under monitoring of bispectral index and blood volume].
    Masui. The Japanese journal of anesthesiology, 2006, Volume: 55, Issue:1

    Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Volume Dete

2006
Use of the Esophageal Doppler Machine to help guide the intraoperative management of two children with pheochromocytoma.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:8

    Topics: Adolescent; Adrenal Gland Neoplasms; Anesthesia, General; Anesthetics; Esophagus; Female; Humans; Hy

2006
Bispectral index monitored balanced anesthesia technique for pheochromocytoma resection.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:7

    Topics: Adrenal Gland Neoplasms; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Blo

2007
Additive effect of propofol for attenuation of hypertension in a patient with undiagnosed phaeochromocytoma.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:6

    Topics: Adrenal Gland Neoplasms; Anesthesia, General; Female; Humans; Hypertension; Hypnotics and Sedatives;

2007
Additive effect of propofol for attenuation of hypertension in a patient with undiagnosed phaeochromocytoma.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Anesthesia, General; Blood Pressure; Drug Syne

2008
[Total intravenous anesthesia with propofol and sufentanil for resection of pheochromocytoma].
    Anaesthesiologie und Reanimation, 1997, Volume: 22, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pre

1997
[Continuous infusion of propofol in pheochromocytoma resection].
    Revista espanola de anestesiologia y reanimacion, 1997, Volume: 44, Issue:10

    Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Intravenous; Humans; Male; Pheochromocytoma; Propofol

1997
Cerebral aneurysm surgery in a patient with phaeochromocytoma.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:3

    Topics: Adrenal Gland Neoplasms; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents;

1998
[Changes of blood volume and blood propofol concentration during the anesthetic management of a pheochromocytoma patient].
    Masui. The Japanese journal of anesthesiology, 2002, Volume: 51, Issue:5

    Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Epidural; Anesthesia, General; Blood Volume; Cardiac Out

2002
Propofol-fentanyl anesthesia for pheochromocytoma resection.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:3

    Topics: Adrenal Gland Neoplasms; Anesthesia, Intravenous; Female; Fentanyl; Humans; Middle Aged; Pheochromoc

1991