propofol has been researched along with Pancreatitis in 30 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancreatitis after propofol administration is a rare complication." | 7.80 | [Acute pancreatitis after propofol administration]. ( Buijs, E; Scholten, JG, 2014) |
| "Propofol can cause acute pancreatitis related to hypertriglyceridemia, however, other mechanisms may also exist." | 7.78 | Hypertriglyceridemia independent propofol-induced pancreatitis. ( Aslanian, HR; Muniraj, T, 2012) |
| "The use of propofol is controversial in patients with a history of acute pancreatitis or those taking drugs, including certain chemotherapeutic drugs, that are associated with pancreatitis." | 7.75 | Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk? ( Crawford, MW; Lopez, AV; Pehora, C, 2009) |
| "Hypertriglyceridemia and hypertriglyceridemia-associated pancreatitis are often seen in intensive care patients receiving propofol." | 7.73 | Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: an analysis of frequency and risk factors. ( Devlin, JW; Lau, AK; Tanios, MA, 2005) |
| "We report a case of pancreatitis, which occurred while the patient was on a propofol drip and then recurred after resolution following an inadvertent rechallenge with propofol." | 7.70 | Propofol-induced pancreatitis: recurrence of pancreatitis after rechallenge. ( Kumar, AN; Lim, KG; Schwartz, DE, 1999) |
| "Propofol is a hypnotic agent for induction and maintainance of general anaesthesia and it is used for sedation of critically ill intensive care patients." | 5.40 | [Propofol-induced pancreatitis after surgery for thyroid carcinoma]. ( Lange, K; Rasmussen, BS; Rostgaard-Knudsen, M, 2014) |
| "We encountered two cases of acute pancreatitis in patients with Cushing's disease following transnasal transsphenoidal hypophysectomy." | 5.33 | Can propofol precipitate pancreatitis in patients with Cushing's syndrome? ( Bhagat, H; Chaturvedi, A; Goswami, R; Pandia, MP; Priya, G; Seth, A, 2005) |
| "We report a case of a drug-induced acute pancreatitis that was most likely triggered by a single dosage of propofol." | 5.33 | Acute pancreatitis induced by short-term propofol administration. ( Gottschling, S; Graf, N; Larsen, R; Meyer, S; Reinhard, H, 2005) |
| "She developed acute pancreatitis in the postoperative period." | 5.33 | Acute pancreatitis after anesthesia with propofol in a child with glycogen storage disease type IA. ( Appachi, E; Bustamante, SE, 2006) |
| "The postoperative pancreatitis is a well-known complication." | 5.31 | [Risk of drug-induced acute pancreatitis following propofol anesthesia used in abdominal operations]. ( Dafinova, K; Iarŭmov, N; Ivanov, A; Khinev, S; Tsoneva, D, 2000) |
| "The incidence of acute pancreatitis in each of the groups was not significant." | 5.30 | Is pancreatitis a complication of propofol infusion? ( Arslan, G; Demirhan, B; Dönmez, A; Pirat, A, 1999) |
| "Hypertriglyceridemia occurred frequently in patients with COVID-19 who received propofol but did not lead to acute pancreatitis." | 4.12 | The Safety of Continuous Infusion Propofol in Mechanically Ventilated Adults With Coronavirus Disease 2019. ( Abedian, S; An, A; Barie, PS; Berger, K; Littlefield, AJ; Witenko, CJ, 2022) |
| "Pancreatitis after propofol administration is a rare complication." | 3.80 | [Acute pancreatitis after propofol administration]. ( Buijs, E; Scholten, JG, 2014) |
| "Propofol can cause acute pancreatitis related to hypertriglyceridemia, however, other mechanisms may also exist." | 3.78 | Hypertriglyceridemia independent propofol-induced pancreatitis. ( Aslanian, HR; Muniraj, T, 2012) |
| "Propofol is a safe sedative drug for ERCP without additional risk of developing acute post-ERCP pancreatitis." | 3.76 | Effects of medications on post-endoscopic retrograde cholangiopancreatography pancreatitis. ( Akerman, M; Bank, S; Fernandes, A; Jalal, PK; Li, N; Novak, S; Sideridis, K; Tieng, A, 2010) |
| "Various case reports have indicated a possible relationship between propofol and pancreatitis." | 3.75 | Dose-related effect of propofol on pancreatic enzymes and triglyceride levels in patients undergoing non-abdominal surgery. ( Panda, NB; Pradeep, K; Prasad, R; Wig, J, 2009) |
| "The use of propofol is controversial in patients with a history of acute pancreatitis or those taking drugs, including certain chemotherapeutic drugs, that are associated with pancreatitis." | 3.75 | Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk? ( Crawford, MW; Lopez, AV; Pehora, C, 2009) |
| "Hypertriglyceridemia and hypertriglyceridemia-associated pancreatitis are often seen in intensive care patients receiving propofol." | 3.73 | Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: an analysis of frequency and risk factors. ( Devlin, JW; Lau, AK; Tanios, MA, 2005) |
| "We report a case of pancreatitis, which occurred while the patient was on a propofol drip and then recurred after resolution following an inadvertent rechallenge with propofol." | 3.70 | Propofol-induced pancreatitis: recurrence of pancreatitis after rechallenge. ( Kumar, AN; Lim, KG; Schwartz, DE, 1999) |
| "Propofol is a potent intravenous anesthetic agent that rapidly induces sedation and unconsciousness." | 2.47 | Clinical effects and lethal and forensic aspects of propofol. ( Levy, RJ, 2011) |
| "Midazolam can also cause paradoxical reactions, including increased agitation, poor co-operation and aggressive or violent behaviour, which has been successfully managed with flumazenil." | 2.42 | Toxicity of intravenous anaesthetics. ( Short, TG; Young, Y, 2003) |
| "Propofol is a hypnotic agent for induction and maintainance of general anaesthesia and it is used for sedation of critically ill intensive care patients." | 1.40 | [Propofol-induced pancreatitis after surgery for thyroid carcinoma]. ( Lange, K; Rasmussen, BS; Rostgaard-Knudsen, M, 2014) |
| "We encountered two cases of acute pancreatitis in patients with Cushing's disease following transnasal transsphenoidal hypophysectomy." | 1.33 | Can propofol precipitate pancreatitis in patients with Cushing's syndrome? ( Bhagat, H; Chaturvedi, A; Goswami, R; Pandia, MP; Priya, G; Seth, A, 2005) |
| "We report a case of a drug-induced acute pancreatitis that was most likely triggered by a single dosage of propofol." | 1.33 | Acute pancreatitis induced by short-term propofol administration. ( Gottschling, S; Graf, N; Larsen, R; Meyer, S; Reinhard, H, 2005) |
| "She developed acute pancreatitis in the postoperative period." | 1.33 | Acute pancreatitis after anesthesia with propofol in a child with glycogen storage disease type IA. ( Appachi, E; Bustamante, SE, 2006) |
| "The postoperative pancreatitis is a well-known complication." | 1.31 | [Risk of drug-induced acute pancreatitis following propofol anesthesia used in abdominal operations]. ( Dafinova, K; Iarŭmov, N; Ivanov, A; Khinev, S; Tsoneva, D, 2000) |
| "The incidence of acute pancreatitis in each of the groups was not significant." | 1.30 | Is pancreatitis a complication of propofol infusion? ( Arslan, G; Demirhan, B; Dönmez, A; Pirat, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 15 (50.00) | 29.6817 |
| 2010's | 8 (26.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Witenko, CJ | 1 |
| Littlefield, AJ | 1 |
| Abedian, S | 1 |
| An, A | 1 |
| Barie, PS | 1 |
| Berger, K | 1 |
| Kumar, G | 1 |
| Scholten, JG | 1 |
| Buijs, E | 1 |
| Lange, K | 1 |
| Rostgaard-Knudsen, M | 1 |
| Rasmussen, BS | 1 |
| Pradeep, K | 1 |
| Wig, J | 1 |
| Panda, NB | 1 |
| Prasad, R | 1 |
| Crawford, MW | 1 |
| Pehora, C | 1 |
| Lopez, AV | 1 |
| Li, N | 1 |
| Tieng, A | 1 |
| Novak, S | 1 |
| Fernandes, A | 1 |
| Jalal, PK | 1 |
| Akerman, M | 1 |
| Sideridis, K | 1 |
| Bank, S | 1 |
| Levy, RJ | 1 |
| Ting, TW | 1 |
| Lee, JH | 1 |
| Rinehart, JB | 1 |
| Baker, B | 1 |
| Raphael, D | 1 |
| Muniraj, T | 1 |
| Aslanian, HR | 1 |
| Fariña Castro, R | 1 |
| Monzón Rubio, E | 1 |
| Ojeda Betancor, N | 1 |
| Rodríguez-Pérez, A | 1 |
| Short, TG | 1 |
| Young, Y | 1 |
| Nouri, M | 1 |
| Martin, D | 1 |
| López Almaraz, R | 1 |
| García Sáiz, MM | 1 |
| Montesdeoca Melián, A | 1 |
| Requena Quesada, GM | 1 |
| Bopp, C | 1 |
| Plachky, J | 1 |
| Hofer, S | 1 |
| Graf, BM | 1 |
| Weigand, MA | 1 |
| Priya, G | 1 |
| Bhagat, H | 1 |
| Pandia, MP | 1 |
| Chaturvedi, A | 1 |
| Seth, A | 1 |
| Goswami, R | 1 |
| Devlin, JW | 1 |
| Lau, AK | 1 |
| Tanios, MA | 1 |
| Gottschling, S | 1 |
| Larsen, R | 1 |
| Meyer, S | 1 |
| Graf, N | 1 |
| Reinhard, H | 1 |
| Bustamante, SE | 1 |
| Appachi, E | 1 |
| Leisure, GS | 1 |
| O'Flaherty, J | 1 |
| Green, L | 1 |
| Jones, DR | 1 |
| Wingfield, TW | 1 |
| Miller, LJ | 1 |
| Wiles-Pfeifler, R | 1 |
| Kumar, AN | 1 |
| Schwartz, DE | 1 |
| Lim, KG | 1 |
| Dönmez, A | 2 |
| Arslan, G | 2 |
| Pirat, A | 1 |
| Demirhan, B | 1 |
| Sener, M | 1 |
| Candan, S | 1 |
| Bird, H | 1 |
| Brim, V | 1 |
| Khinev, S | 1 |
| Tsoneva, D | 1 |
| Dafinova, K | 1 |
| Iarŭmov, N | 1 |
| Ivanov, A | 1 |
| Betrosian, AP | 1 |
| Balla, M | 1 |
| Papanikolaou, M | 1 |
| Kofinas, G | 1 |
| Georgiadis, G | 1 |
| Jawaid, Q | 1 |
| Presti, ME | 1 |
| Neuschwander-Tetri, BA | 1 |
| Burton, FR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of Analgesics and Sedatives in Mechanically Ventilated Patients With COVID-19[NCT05336656] | 353 participants (Actual) | Observational | 2022-01-01 | Completed | |||
| An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia[NCT04235894] | 124 participants (Actual) | Observational | 2016-09-07 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for propofol and Pancreatitis
| Article | Year |
|---|---|
Clinical effects and lethal and forensic aspects of propofol.
Topics: Accidents; Acidosis; Acute Kidney Injury; Bacteremia; Bradycardia; Drug Overdose; Dyslipidemias; For | 2011 |
Toxicity of intravenous anaesthetics.
Topics: Anesthetics, Intravenous; Humans; Hyperlipidemias; Ketamine; Midazolam; Nervous System; Pancreatitis | 2003 |
Propofol for the long-term sedation of a critically ill patient.
Topics: Adult; Conscious Sedation; Critical Care; Critical Illness; Humans; Hypnotics and Sedatives; Infusio | 1998 |
Acute pancreatitis after single-dose exposure to propofol: a case report and review of literature.
Topics: Acute Disease; Adult; Anesthetics, Intravenous; Female; Humans; Pancreatitis; Propofol | 2002 |
1 trial available for propofol and Pancreatitis
| Article | Year |
|---|---|
Can we blame propofol for pancreatitis?
Topics: Amylases; Anesthetics, Intravenous; Cholesterol; Humans; Lipase; Pancreatitis; Propofol; Thiopental; | 1999 |
25 other studies available for propofol and Pancreatitis
| Article | Year |
|---|---|
The Safety of Continuous Infusion Propofol in Mechanically Ventilated Adults With Coronavirus Disease 2019.
Topics: Acute Disease; Adult; COVID-19; Humans; Intensive Care Units; Pancreatitis; Propofol; Respiration, A | 2022 |
Propofol as a Cause of Recurrent Pancreatitis in A Child with ESRD; A Cautionary Tale.
Topics: Anesthetics, Intravenous; Child; Female; Humans; Kidney Failure, Chronic; Pancreatitis; Propofol; Re | 2019 |
[Acute pancreatitis after propofol administration].
Topics: Acute Disease; Aged; Anesthetics, Intravenous; Humans; Male; Pancreatitis; Propofol | 2014 |
[Propofol-induced pancreatitis after surgery for thyroid carcinoma].
Topics: Anesthetics, Intravenous; Humans; Male; Middle Aged; Pancreatitis; Postoperative Complications; Prop | 2014 |
Dose-related effect of propofol on pancreatic enzymes and triglyceride levels in patients undergoing non-abdominal surgery.
Topics: Acute Disease; Adolescent; Adult; Amylases; Anesthetics, Intravenous; Dose-Response Relationship, Dr | 2009 |
Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk?
Topics: Acute Disease; Adolescent; Anesthesia, General; Anesthetics, Intravenous; Antineoplastic Agents; Chi | 2009 |
Effects of medications on post-endoscopic retrograde cholangiopancreatography pancreatitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Cholangiopancreatograp | 2010 |
Acute pancreatitis after propofol infusion in a teenage patient.
Topics: Acute Disease; Adolescent; Anesthetics, Intravenous; Conscious Sedation; Fatal Outcome; Female; Huma | 2012 |
Postoperative global amnesia reversed with flumazenil.
Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desfluran | 2012 |
Hypertriglyceridemia independent propofol-induced pancreatitis.
Topics: Acute Disease; Aged; Humans; Hypertriglyceridemia; Male; Pancreatitis; Propofol | 2012 |
[Necro-hemorrhagic pancreatitis after prolonged propofol perfusion].
Topics: Adult; Hemorrhage; Humans; Hypnotics and Sedatives; Male; Necrosis; Pancreatic Diseases; Pancreatiti | 2002 |
[Postoperative pancreatitis after non abdominal surgery].
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intraveno | 2003 |
[Acute pancreatitis after anesthesia with propofol in a teenage boy treated with liposomal amphotericin B].
Topics: Acute Disease; Adolescent; Amphotericin B; Anesthetics, Intravenous; Anti-Bacterial Agents; Humans; | 2004 |
[Anesthesia and intensive care medicine--status report. XIIIth International Symposium on Anesthesia in Heidelberg, March 19-21, 2004].
Topics: Anesthesia; Anesthesia, Conduction; Anesthesiology; Anesthetics, Intravenous; Blood Transfusion; Car | 2004 |
Can propofol precipitate pancreatitis in patients with Cushing's syndrome?
Topics: Acute Disease; Adult; Amylases; Anesthetics, Intravenous; Cushing Syndrome; Female; Humans; Hypophys | 2005 |
Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: an analysis of frequency and risk factors.
Topics: Acute Disease; Adult; Aged; Female; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; Intensive | 2005 |
Acute pancreatitis induced by short-term propofol administration.
Topics: Acute Disease; Acute Kidney Injury; Anesthetics, Intravenous; Brain Neoplasms; Child; Combined Modal | 2005 |
Acute pancreatitis after anesthesia with propofol in a child with glycogen storage disease type IA.
Topics: Adenoidectomy; Ambulatory Surgical Procedures; Anesthetics, Intravenous; Child; Female; Glycogen Sto | 2006 |
Propofol and postoperative pancreatitis.
Topics: Acute Disease; Adult; Anesthesia, General; Anesthetics, Intravenous; Humans; Male; Pancreatitis; Pro | 1996 |
Pancreatitis after propofol administration: is there a relationship?
Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Humans; Middle Aged; Pancreatitis; Postoperativ | 1996 |
Propofol-induced pancreatitis: recurrence of pancreatitis after rechallenge.
Topics: Female; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; Middle Aged; Pancreatitis; Propofol; | 1999 |
Is pancreatitis a complication of propofol infusion?
Topics: Acute Disease; Amylases; Anesthetics, Intravenous; Animals; Cholesterol; Female; Lipase; Pancreas; P | 1999 |
Propofol and postoperative pancreatitis.
Topics: Acute Disease; Adult; Anesthetics, Intravenous; Humans; Male; Pancreatitis; Postoperative Complicati | 2000 |
[Risk of drug-induced acute pancreatitis following propofol anesthesia used in abdominal operations].
Topics: Abdomen; Acute Disease; Adult; Aged; Anesthetics, Intravenous; Humans; Middle Aged; Pancreatitis; Pr | 2000 |
Post-operative pancreatitis after propofol administration.
Topics: Acute Disease; Adult; Anesthetics, Intravenous; Humans; Male; Pancreatitis; Propofol | 2001 |