propofol has been researched along with Pancreatic Neoplasms in 17 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Removal of the tumor was performed under propofol, nitrous oxide, and epidural anesthesia." | 7.70 | [Propofol anesthesia for a patient with insulinoma]. ( Amaki, Y; Fujiwara, C; Kamide, M; Onozawa, H; Sato, Y; Tanifuji, Y, 1998) |
| "This pruritus is often intractable and resistant to conventional treatment." | 5.28 | Propofol and cholestatic pruritus. ( Borgeat, A; Huber, O; Mentha, G; Wilder-Smith, O, 1992) |
| " Removal of the tumor was performed under propofol, nitrous oxide, and epidural anesthesia." | 3.70 | [Propofol anesthesia for a patient with insulinoma]. ( Amaki, Y; Fujiwara, C; Kamide, M; Onozawa, H; Sato, Y; Tanifuji, Y, 1998) |
| "Propofol is a commonly used anesthetic with controversial effects on cancer cells." | 1.62 | Propofol mediates pancreatic cancer cell activity through the repression of ADAM8 via SP1. ( Ben-David, Y; Gao, Y; Sample, KM; Wang, C; Yu, X; Zhou, Y, 2021) |
| " At the same time, using nanoemulsion as a carrier in a drug delivery system can improve the solubility and loading capacity of poorly soluble drugs, and increase the absorption rate and bioavailability of fat-soluble drugs in the body." | 1.62 | Effect of Compound Propofol Nanoemulsion on Immune Function in Patients with Pancreatic Cancer. ( Wang, Z; Zhou, S, 2021) |
| "The propofol anesthesia was associated with improved survival (hazard ratio, 0." | 1.56 | Propofol-based intravenous anesthesia is associated with better survival than desflurane anesthesia in pancreatic cancer surgery. ( Chen, JY; Hung, KC; Lai, HC; Lee, MS; Lin, KT; Liu, YT; Wu, ZF, 2020) |
| "Propofol is a commonly used intravenous anesthetic." | 1.42 | Propofol suppresses proliferation and invasion of pancreatic cancer cells by upregulating microRNA-133a expression. ( Dong, TL; Gong, HY; Liu, DJ; Wang, ZT; Zheng, F, 2015) |
| "We used the human pancreatic cancer cell line MIAPaCa-2 for in vitro studies measuring growth inhibition and degree of apoptotic cell death induced by propofol alone, gemcitabine alone, or propofol followed by gemcitabine." | 1.39 | Propofol induces apoptosis and increases gemcitabine sensitivity in pancreatic cancer cells in vitro by inhibition of nuclear factor-κB activity. ( Du, QH; He, CY; Xu, YB; Yun, P; Zhang, MY, 2013) |
| "This pruritus is often intractable and resistant to conventional treatment." | 1.28 | Propofol and cholestatic pruritus. ( Borgeat, A; Huber, O; Mentha, G; Wilder-Smith, O, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 6 (35.29) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, Y | 3 |
| Zhou, Y | 1 |
| Wang, C | 1 |
| Sample, KM | 1 |
| Yu, X | 4 |
| Ben-David, Y | 1 |
| Oh, TK | 1 |
| Jo, H | 1 |
| Song, IA | 1 |
| Malsy, M | 1 |
| Graf, B | 1 |
| Bruendl, E | 1 |
| Maier-Stocker, C | 1 |
| Bundscherer, A | 1 |
| Shi, J | 1 |
| Wang, X | 1 |
| Zhang, F | 3 |
| Lai, HC | 1 |
| Lee, MS | 1 |
| Liu, YT | 1 |
| Lin, KT | 1 |
| Hung, KC | 1 |
| Chen, JY | 1 |
| Wu, ZF | 1 |
| Wang, Z | 1 |
| Zhou, S | 1 |
| Dai, J | 1 |
| Du, QH | 1 |
| Xu, YB | 1 |
| Zhang, MY | 1 |
| Yun, P | 1 |
| He, CY | 1 |
| Wang, ZT | 1 |
| Gong, HY | 1 |
| Zheng, F | 1 |
| Liu, DJ | 1 |
| Dong, TL | 1 |
| Knežević, A | 1 |
| Stojšić, M | 1 |
| Gvozdenović, L | 1 |
| Marandola, M | 1 |
| Cilli, T | 1 |
| Alessandri, F | 1 |
| Tellan, G | 1 |
| Caronna, R | 1 |
| Chirletti, P | 1 |
| Delogu, G | 1 |
| Chu, YL | 1 |
| Wang, XF | 1 |
| Gao, XZ | 1 |
| Qiao, XL | 1 |
| Liu, F | 1 |
| Yu, SY | 1 |
| Zhang, J | 1 |
| Moser, B | 1 |
| Lirk, P | 1 |
| Lechner, M | 1 |
| Gottardis, M | 1 |
| Sato, Y | 1 |
| Onozawa, H | 1 |
| Fujiwara, C | 1 |
| Kamide, M | 1 |
| Tanifuji, Y | 1 |
| Amaki, Y | 1 |
| Kunisawa, T | 1 |
| Takahata, O | 1 |
| Yamamoto, Y | 1 |
| Sengoku, K | 1 |
| Iwasaki, H | 1 |
| Borgeat, A | 1 |
| Wilder-Smith, O | 1 |
| Mentha, G | 1 |
| Huber, O | 1 |
2 trials available for propofol and Pancreatic Neoplasms
| Article | Year |
|---|---|
Perioperative management in patients undergoing pancreatic surgery: the anesthesiologist's point of view.
Topics: Anastomosis, Roux-en-Y; Anesthesia; Anesthetics, Intravenous; Humans; Intraoperative Period; Pain, P | 2008 |
Endoscopic ultrasonography in tandem with endoscopic retrograde cholangiopancreatography in the management of suspected distal obstructive jaundice.
Topics: Aged; Anesthetics, Intravenous; Biliary Tract Neoplasms; Cholangiopancreatography, Endoscopic Retrog | 2013 |
15 other studies available for propofol and Pancreatic Neoplasms
| Article | Year |
|---|---|
Propofol mediates pancreatic cancer cell activity through the repression of ADAM8 via SP1.
Topics: ADAM Proteins; Anesthetics, Intravenous; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Prolifera | 2021 |
Propofol-based intravenous anesthesia is associated with improved survival outcomes after major cancer surgery: a nationwide cohort study in South Korea.
Topics: Adult; Anesthesia, Intravenous; Cohort Studies; Colorectal Neoplasms; Humans; Pancreatic Neoplasms; | 2023 |
Over-expression of cFos by the Transcription Factors NFATc2 and Sp1 in Pancreatic Cancer Cells.
Topics: Humans; Pancreas; Pancreatic Neoplasms; Propofol; Sp1 Transcription Factor; Transcription Factors | 2023 |
Over-expression of cFos by the Transcription Factors NFATc2 and Sp1 in Pancreatic Cancer Cells.
Topics: Humans; Pancreas; Pancreatic Neoplasms; Propofol; Sp1 Transcription Factor; Transcription Factors | 2023 |
Over-expression of cFos by the Transcription Factors NFATc2 and Sp1 in Pancreatic Cancer Cells.
Topics: Humans; Pancreas; Pancreatic Neoplasms; Propofol; Sp1 Transcription Factor; Transcription Factors | 2023 |
Over-expression of cFos by the Transcription Factors NFATc2 and Sp1 in Pancreatic Cancer Cells.
Topics: Humans; Pancreas; Pancreatic Neoplasms; Propofol; Sp1 Transcription Factor; Transcription Factors | 2023 |
Propofol affects the growth and metastasis of pancreatic cancer via ADAM8.
Topics: ADAM Proteins; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Prol | 2020 |
Propofol-based intravenous anesthesia is associated with better survival than desflurane anesthesia in pancreatic cancer surgery.
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Female | 2020 |
Effect of Compound Propofol Nanoemulsion on Immune Function in Patients with Pancreatic Cancer.
Topics: Anesthesia, Intravenous; Humans; Immunity; Pancreatic Neoplasms; Propofol; Remifentanil | 2021 |
Propofol inhibits pancreatic cancer proliferation and metastasis by up-regulating miR-328 and down-regulating ADAM8.
Topics: ADAM Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Down-Regulation; | 2019 |
Propofol inhibits pancreatic cancer progress under hypoxia via ADAM8.
Topics: ADAM Proteins; Animals; Antigens, CD; Biomarkers, Tumor; Blotting, Western; Cell Hypoxia; Cell Line, | 2019 |
Propofol induces apoptosis and increases gemcitabine sensitivity in pancreatic cancer cells in vitro by inhibition of nuclear factor-κB activity.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Lin | 2013 |
Propofol suppresses proliferation and invasion of pancreatic cancer cells by upregulating microRNA-133a expression.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Mic | 2015 |
Safety and clinical effectiveness of propofol for endoscopic retrograde cholangiopancreatography.
Topics: Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Choledocholi | 2016 |
Safety and clinical effectiveness of propofol for endoscopic retrograde cholangiopancreatography.
Topics: Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Choledocholi | 2016 |
Safety and clinical effectiveness of propofol for endoscopic retrograde cholangiopancreatography.
Topics: Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Choledocholi | 2016 |
Safety and clinical effectiveness of propofol for endoscopic retrograde cholangiopancreatography.
Topics: Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Choledocholi | 2016 |
General anaesthesia in a patient with motor neuron disease.
Topics: Amyotrophic Lateral Sclerosis; Anesthesia, General; Anesthetics, Intravenous; Atracurium; Carcinoma; | 2004 |
[Propofol anesthesia for a patient with insulinoma].
Topics: Anesthesia; Anesthesia, Epidural; Anesthetics, Intravenous; Blood Glucose; Female; Humans; Insulinom | 1998 |
[Anesthetic management of two patients with insulinoma using propofol--in association with rapid radioimmunoassay for insulin].
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Female; Glucose; Humans; Insulin; Insulinoma; Intra | 2001 |
Propofol and cholestatic pruritus.
Topics: Aged; Cholestasis; Drug Administration Schedule; Female; Humans; Male; Pancreatic Neoplasms; Propofo | 1992 |