Page last updated: 2024-11-03

propofol and Pain, Procedural

propofol has been researched along with Pain, Procedural in 26 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Pain, Procedural: Pain associated with examination, treatment or procedures.

Research Excerpts

ExcerptRelevanceReference
"Music therapy added to deep sedation administered by anesthesiologists provided decreased anxiety score and propofol consumption."5.27Evaluation of pain and patient satisfaction by music therapy in patients with endoscopy/colonoscopy. ( Akçalı, D; Bashiri, M; Çifdalöz, BU; Cindoruk, M; Coşkun, D; Dikmen, A, 2018)
"When administered ~5 min prior to entering the OR, propofol, 20mg IV, was as effective as midazolam 2mg IV in reducing anxiety."5.22Propofol versus midazolam for premedication: a placebo‑controlled, randomized double‑blinded study. ( Anand, KK; Cao, X; Elvir Lazo, OL; Hausman, J; Hemaya, EG; Hernandez Conte, A; Tang, J; Wender, RH; White, PF; Yumul, F; Yumul, R; Zhang, X, 2016)
"To assess the trends in nonoperating room anesthesia (NORA) for gastrointestinal endoscopy over the past few years, and to describe alternative methods of delivering propofol sedation in selected low-risk patients."4.98Nonoperating room anesthesia for gastrointestinal endoscopic procedures. ( Lin, OS; Weigel, W, 2018)
"This study attempted to investigate the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on painless induced abortion."3.01Analysis on the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on hemodynamics and analgesia in pregnant females undergoing painless induced abortion. ( Han, Y; Liu, Z; Wu, J; Yang, L, 2021)
"Morbid obesity is associated with adverse airway events including desaturation during deep sedation."2.90High-flow versus standard nasal cannula in morbidly obese patients during colonoscopy: A prospective, randomized clinical trial. ( Fox, AA; Minhajuddin, A; Nasir, D; Riccio, CA; Sarmiento, S, 2019)
"Sufentanil has favourable pharmacodynamic and pharmacokinetic properties as an opioid, and it is usually co-administered with propofol as intravenous anaesthesia for hysteroscopic examination or therapeutic surgery."2.90ED50 of propofol in combination with low-dose sufentanil for intravenous anaesthesia in hysteroscopy. ( Chen, H; Li, Y; Liu, C; Song, Y; Xiang, B; Yu, J, 2019)
" There was no serious adverse event in both groups."2.84Adverse Events With Ketamine Versus Ketofol for Procedural Sedation on Adults: A Double-blind, Randomized Controlled Trial. ( Ageron, FX; Boiffier, M; Contenti, J; Fournier, M; Giolito, D; Istria, J; Lemoel, F; Levraut, J; Rapp, J, 2017)
" lidocaine reduced propofol dosage required for gastrointestinal endoscopic procedures (SMD=-0."2.82Impact of intravenous and topical lidocaine on clinical outcomes in patients receiving propofol for gastrointestinal endoscopic procedures: a meta-analysis of randomised controlled trials. ( Chang, YJ; Chang, YP; Chen, JY; Ho, CN; Hung, KC; Lan, KM; Lin, YT; Sun, CK; Wang, LK; Yew, M, 2022)
"We present a case of rapid respiratory failure in an otherwise healthy and young patient who used a vaporiser containing tetrahydrocannabinol (THC) during the month prior to admission."1.56Sedation challenges in patients with E-cigarette, or vaping, product use-associated lung injury (EVALI). ( Markowski, LM; Maslonka, MA; Miller, PJ; Schertz, AR, 2020)
"Pre-treatment with lidocaine or flurbiprofen axetil has proven to be effectual in the reduction propofol-induced pain in adults."1.56Clinical therapeutic effects of lidocaine combination with flurbiprofen axetil for reducing propofol-induced pain in adults: A protocol for systematic review and meta-analysis. ( Fu, J; Lu, G; Sun, W; Ye, X; Yu, J, 2020)
" Adverse events in CAPS patients were recorded."1.51Computer-Assisted Propofol Sedation for Esophagogastroduodenoscopy Is Effective, Efficient, and Safe. ( Beecher, R; Chiorean, M; Drennan, F; Gluck, M; Koch, J; Kozarek, RA; La Selva, D; Larsen, M; Lin, OS; McCormick, S; Ross, A; Tombs, D; Venu, N; Weigel, W, 2019)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's18 (69.23)24.3611
2020's8 (30.77)2.80

Authors

AuthorsStudies
Wu, J1
Han, Y1
Yang, L1
Liu, Z1
Hung, KC1
Yew, M1
Lin, YT1
Chen, JY1
Wang, LK1
Chang, YJ1
Chang, YP1
Lan, KM1
Ho, CN1
Sun, CK1
Cruickshank, A1
Qeadan, F1
Kuttesch, JF1
Agarwal, HS1
Faruki, A1
Nguyen, T1
Proeschel, S1
Levy, N1
Yu, J3
Ip, V1
Mueller, A1
Banner-Goodspeed, V1
O'Gara, B1
Payen, JF1
Chanques, G1
Futier, E1
Velly, L1
Jaber, S1
Constantin, JM1
Rezniczek, GA1
Hecken, JM1
Rehman, S1
Dogan, A1
Tempfer, CB1
Hilal, Z1
Maslonka, MA1
Schertz, AR1
Markowski, LM1
Miller, PJ1
Sun, W1
Lu, G1
Ye, X1
Fu, J1
Jung, J1
Kim, B1
Park, SN1
Lee, J2
Choi, I1
Lee, MJ1
Yim, H1
Lee, C1
Jacquin, PH1
Ciais, JF1
Marrec, A1
Hebert, P1
Lemoel, F1
Contenti, J1
Giolito, D1
Boiffier, M1
Rapp, J1
Istria, J1
Fournier, M1
Ageron, FX1
Levraut, J1
Bugajski, M1
Wieszczy, P1
Hoff, G1
Rupinski, M1
Regula, J1
Kaminski, MF1
Cakirgöz, MY1
Demirel, I1
Duran, E1
Özer, AB1
Türkmen, UA1
Ersoy, A1
Aksu, A1
Hancı, V1
Mackey, EF1
Chayapathi, V1
Kalra, M1
Bakshi, AS1
Mahajan, A1
Lin, OS2
Weigel, W2
Leslie, K1
Sgroi, J1
Zhang, W1
Zhu, Z1
Zheng, Y1
Wang, Z1
Hu, Z1
Dai, T1
Bashiri, M1
Akçalı, D1
Coşkun, D1
Cindoruk, M1
Dikmen, A1
Çifdalöz, BU1
Riccio, CA1
Sarmiento, S1
Minhajuddin, A1
Nasir, D1
Fox, AA1
Smith, ZL1
Das, KK1
Kushnir, VM1
La Selva, D1
Kozarek, RA1
Tombs, D1
Beecher, R1
Koch, J1
McCormick, S1
Chiorean, M1
Drennan, F1
Gluck, M1
Venu, N1
Larsen, M1
Ross, A1
Xiang, B1
Song, Y1
Chen, H1
Li, Y1
Liu, C1
Navidi, B1
Kiai, K1
Elvir Lazo, OL1
White, PF1
Tang, J1
Yumul, R1
Cao, X1
Yumul, F1
Hausman, J1
Hernandez Conte, A1
Anand, KK1
Hemaya, EG1
Zhang, X1
Wender, RH1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Topical Lidocaine/Prilocaine in Pain Management in Pleurocentesis[NCT05984264]Phase 4118 participants (Anticipated)Interventional2023-01-01Recruiting
Immersive Virtual Reality Improves Satisfaction In Laboring Women[NCT05032456]42 participants (Actual)Interventional2020-11-13Completed
Virtual Reality in the Operating Room: Using Immersive Relaxation as an Adjunct to Anesthesia[NCT03614325]32 participants (Anticipated)Interventional2018-12-04Active, not recruiting
Large Loop Excision of the Transformation Zone (LLETZ) With Versus Without Intraoperative Application of Lugol's Iodine in Women With Cervical Dysplasia: a Prospective Randomized Trial[NCT05132114]216 participants (Anticipated)Interventional2022-01-17Recruiting
Large Loop Excision of the Transformatione Zone Under General Versus Local Anesthesia: a Randomized Trial.[NCT03494686]229 participants (Actual)Interventional2018-04-03Completed
The Optimal Sequence in Same-day Bidirectional Endoscopy Under Deep Anesthesia Induced by Propofol Combined With Fentanyl: A Prospective Randomized Controlled ,Two Centers Trial[NCT04973878]544 participants (Anticipated)Interventional2021-07-30Not yet recruiting
Influence of Adequacy of Anaesthesia Monitoring on Both Operators' and Patients' Satisfaction in Patients Undergoing Colonoscopic Procedures[NCT03922815]158 participants (Actual)Interventional2019-09-01Completed
Three Distraction Methods for Pain Reduction During Colonoscopy: A Randomized Controlled Trial Evaluating the Effects on Pain and Anxiety[NCT05378165]30 participants (Actual)Interventional2022-02-07Completed
The Effect of Music on Colonoscopy (MUSICOL): A Randomized Controlled Trial[NCT04628052]200 participants (Anticipated)Interventional2020-11-20Recruiting
Investigation of the Clinical Efficacy of High Flow Nasal Oxygen in Patients Over 60 Years of Age Undergoing Colonoscopy[NCT05396274]70 participants (Anticipated)Interventional2022-05-26Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for propofol and Pain, Procedural

ArticleYear
Impact of intravenous and topical lidocaine on clinical outcomes in patients receiving propofol for gastrointestinal endoscopic procedures: a meta-analysis of randomised controlled trials.
    British journal of anaesthesia, 2022, Volume: 128, Issue:4

    Topics: Anesthesia; Endoscopy, Gastrointestinal; Humans; Lidocaine; Pain, Procedural; Propofol; Randomized C

2022
Sedation for critically ill patients with COVID-19: Which specificities? One size does not fit all.
    Anaesthesia, critical care & pain medicine, 2020, Volume: 39, Issue:3

    Topics: Analgesics, Opioid; Betacoronavirus; Coronavirus Infections; COVID-19; Critical Illness; Deep Sedati

2020
Nonoperating room anesthesia for gastrointestinal endoscopic procedures.
    Current opinion in anaesthesiology, 2018, Volume: 31, Issue:4

    Topics: Anesthesia; Anesthesiology; Conscious Sedation; Endoscopy, Gastrointestinal; Health Care Costs; Huma

2018
Sedation for gastrointestinal endoscopy in Australia: what is the same and what is different?
    Current opinion in anaesthesiology, 2018, Volume: 31, Issue:4

    Topics: Airway Management; Anesthesia; Australia; Conscious Sedation; Deep Sedation; Endoscopy, Gastrointest

2018
Effect and safety of propofol for sedation during colonoscopy: A meta-analysis.
    Journal of clinical anesthesia, 2018, Volume: 51

    Topics: Colonoscopy; Deep Sedation; Humans; Hypnotics and Sedatives; Pain, Procedural; Patient Satisfaction;

2018
The comparison of propofol and midazolam for bronchoscopy: A meta-analysis of randomized controlled studies.
    Medicine, 2018, Volume: 97, Issue:36

    Topics: Anesthetics, Intravenous; Bronchoscopy; Humans; Hypnotics and Sedatives; Midazolam; Pain, Procedural

2018
Efficiency and scheduling in the nonoperating room anesthesia suite: implications from patient satisfaction to increased revenue operating room: a common (Dollars and Sense) approach.
    Current opinion in anaesthesiology, 2019, Volume: 32, Issue:4

    Topics: Ambulatory Care Facilities; Conscious Sedation; Efficiency, Organizational; Endoscopy, Gastrointesti

2019

Trials

11 trials available for propofol and Pain, Procedural

ArticleYear
Analysis on the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on hemodynamics and analgesia in pregnant females undergoing painless induced abortion.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:3(Special)

    Topics: Abortion, Induced; Adult; Anesthetics, Intravenous; Arterial Pressure; Carrageenan; Deep Sedation; D

2021
Virtual reality as an adjunct to anesthesia in the operating room.
    Trials, 2019, Dec-27, Volume: 20, Issue:1

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Intravenous; Anxiety; Humans; Operating Rooms; Orthopedi

2019
Virtual reality as an adjunct to anesthesia in the operating room.
    Trials, 2019, Dec-27, Volume: 20, Issue:1

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Intravenous; Anxiety; Humans; Operating Rooms; Orthopedi

2019
Virtual reality as an adjunct to anesthesia in the operating room.
    Trials, 2019, Dec-27, Volume: 20, Issue:1

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Intravenous; Anxiety; Humans; Operating Rooms; Orthopedi

2019
Virtual reality as an adjunct to anesthesia in the operating room.
    Trials, 2019, Dec-27, Volume: 20, Issue:1

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Intravenous; Anxiety; Humans; Operating Rooms; Orthopedi

2019
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes

2020
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes

2020
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes

2020
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:6

    Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes

2020
Impact of the Timing of Rocuronium Injection after Propofol Administration on Temporal Summation of Pain in Gynecologic Laparoscopic Surgery: A Prospective and Controlled Study.
    Pain research & management, 2020, Volume: 2020

    Topics: Administration, Intravenous; Adult; Analgesics; Double-Blind Method; Female; Gynecologic Surgical Pr

2020
Adverse Events With Ketamine Versus Ketofol for Procedural Sedation on Adults: A Double-blind, Randomized Controlled Trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:12

    Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Intravenous; Double-Blind Method; Female; Hemodyna

2017
Gabapentin pretreatment for propofol and rocuronium injection pain: A randomized, double-blind, placebo-controlled study.
    Nigerian journal of clinical practice, 2018, Volume: 21, Issue:1

    Topics: Adult; Amines; Analgesics; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Cyclohexanec

2018
A comparison of ketamine + midazolam to propofol for procedural sedation for lumbar puncture in pediatric oncology by nonanesthesiologists-a randomized comparative trial.
    Pediatric blood & cancer, 2018, Volume: 65, Issue:8

    Topics: Antineoplastic Agents; Child; Child, Preschool; Conscious Sedation; Female; Humans; Hypnotics and Se

2018
Evaluation of pain and patient satisfaction by music therapy in patients with endoscopy/colonoscopy.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Anxiety; Colonoscopy; Combined Modality Therapy; Conscious Sedation; Double

2018
Evaluation of pain and patient satisfaction by music therapy in patients with endoscopy/colonoscopy.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Anxiety; Colonoscopy; Combined Modality Therapy; Conscious Sedation; Double

2018
Evaluation of pain and patient satisfaction by music therapy in patients with endoscopy/colonoscopy.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Anxiety; Colonoscopy; Combined Modality Therapy; Conscious Sedation; Double

2018
Evaluation of pain and patient satisfaction by music therapy in patients with endoscopy/colonoscopy.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Anxiety; Colonoscopy; Combined Modality Therapy; Conscious Sedation; Double

2018
High-flow versus standard nasal cannula in morbidly obese patients during colonoscopy: A prospective, randomized clinical trial.
    Journal of clinical anesthesia, 2019, Volume: 54

    Topics: Aged; Cannula; Colonoscopy; Deep Sedation; Female; Humans; Hypoxia; Male; Middle Aged; Noninvasive V

2019
ED50 of propofol in combination with low-dose sufentanil for intravenous anaesthesia in hysteroscopy.
    Basic & clinical pharmacology & toxicology, 2019, Volume: 125, Issue:5

    Topics: Adult; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Dose-Response Relation

2019
Propofol versus midazolam for premedication: a placebo‑controlled, randomized double‑blinded study.
    Minerva anestesiologica, 2016, Volume: 82, Issue:11

    Topics: Anesthetics, Intravenous; Anxiety; Conscious Sedation; Double-Blind Method; Female; Humans; Hypnotic

2016

Other Studies

8 other studies available for propofol and Pain, Procedural

ArticleYear
Eutectic mixture of lidocaine and prilocaine versus 1% lidocaine injection for lumbar punctures in pediatric oncology patients.
    Pediatric blood & cancer, 2019, Volume: 66, Issue:11

    Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Child; Female; Fentanyl; Humans; Hypnotic

2019
Sedation challenges in patients with E-cigarette, or vaping, product use-associated lung injury (EVALI).
    BMJ case reports, 2020, Sep-02, Volume: 13, Issue:9

    Topics: Acute Lung Injury; Analgesia; Computed Tomography Angiography; Deep Sedation; Dose-Response Relation

2020
Clinical therapeutic effects of lidocaine combination with flurbiprofen axetil for reducing propofol-induced pain in adults: A protocol for systematic review and meta-analysis.
    Medicine, 2020, Dec-24, Volume: 99, Issue:52

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Drug Therapy, Combination; Flurbiprofen; Humans

2020
Propofol for painful procedures in palliative care.
    BMJ supportive & palliative care, 2021, Volume: 11, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cancer Pain; Female; Hospice and Palliative Care Nursing; Humans; Ma

2021
Modifiable factors associated with patient-reported pain during and after screening colonoscopy.
    Gut, 2018, Volume: 67, Issue:11

    Topics: Benzodiazepines; Colonoscopy; Colorectal Neoplasms; Cross-Sectional Studies; Databases, Factual; Ear

2018
An Extension Study Using Hypnotic Suggestion as an Adjunct to Intravenous Sedation.
    The American journal of clinical hypnosis, 2018, Volume: 60, Issue:4

    Topics: Adult; Anesthetics, Intravenous; Combined Modality Therapy; Humans; Hypnosis; Hypnotics and Sedative

2018
Anesthesia-administered sedation for endoscopic retrograde cholangiopancreatography: monitored anesthesia care or general endotracheal anesthesia?
    Current opinion in anaesthesiology, 2019, Volume: 32, Issue:4

    Topics: Anesthesia, Endotracheal; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Clin

2019
Computer-Assisted Propofol Sedation for Esophagogastroduodenoscopy Is Effective, Efficient, and Safe.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:12

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Anesthetists; Blood Gas Monitorin

2019