propofol has been researched along with Osteogenic Sarcoma in 7 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol suppresses cell proliferation, migration and invasion of osteosarcoma cells through FOXO1/TUSC7 axis by regulating AKT/GSK3β signalling." | 8.02 | Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7. ( Huang, X; Liu, J; Xie, H, 2021) |
| "The different concentrations of propofol were co-incubated with osteosarcoma MG-63 lines for 72 hrs." | 7.83 | Propofol suppresses invasion and induces apoptosis of osteosarcoma cell in vitro via downregulation of TGF-β1 expression. ( Du, QH; Guo, XG; Jiang, W; Li, G; Xu, YB; Zhang, MY; Zhao, FR, 2016) |
| "Propofol-based TIVA was associated with better survival in patients who underwent elective limb-salvage surgery for OS than DES anesthesia." | 5.72 | Propofol-based total intravenous anesthesia is associated with better survival than desflurane anesthesia in limb-salvage surgery for osteosarcoma: A retrospective analysis. ( Hsu, CL; Lai, HC; Lee, MS; Sun, TY; Tseng, WC; Wu, KL; Wu, ZF; Yeh, TT, 2022) |
| "Propofol suppresses cell proliferation, migration and invasion of osteosarcoma cells through FOXO1/TUSC7 axis by regulating AKT/GSK3β signalling." | 4.02 | Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7. ( Huang, X; Liu, J; Xie, H, 2021) |
| "The different concentrations of propofol were co-incubated with osteosarcoma MG-63 lines for 72 hrs." | 3.83 | Propofol suppresses invasion and induces apoptosis of osteosarcoma cell in vitro via downregulation of TGF-β1 expression. ( Du, QH; Guo, XG; Jiang, W; Li, G; Xu, YB; Zhang, MY; Zhao, FR, 2016) |
| "Propofol-based TIVA was associated with better survival in patients who underwent elective limb-salvage surgery for OS than DES anesthesia." | 1.72 | Propofol-based total intravenous anesthesia is associated with better survival than desflurane anesthesia in limb-salvage surgery for osteosarcoma: A retrospective analysis. ( Hsu, CL; Lai, HC; Lee, MS; Sun, TY; Tseng, WC; Wu, KL; Wu, ZF; Yeh, TT, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, TY | 1 |
| Hsu, CL | 1 |
| Lee, MS | 1 |
| Yeh, TT | 1 |
| Lai, HC | 1 |
| Wu, KL | 1 |
| Wu, ZF | 1 |
| Tseng, WC | 1 |
| Huang, X | 1 |
| Liu, J | 1 |
| Xie, H | 1 |
| Ye, Z | 1 |
| Jingzhong, L | 1 |
| Yangbo, L | 1 |
| Lei, C | 1 |
| Jiandong, Y | 1 |
| Xu, YB | 1 |
| Jiang, W | 1 |
| Zhao, FR | 1 |
| Li, G | 1 |
| Du, QH | 1 |
| Zhang, MY | 1 |
| Guo, XG | 1 |
| Mammoto, T | 1 |
| Mukai, M | 1 |
| Mammoto, A | 1 |
| Yamanaka, Y | 1 |
| Hayashi, Y | 1 |
| Mashimo, T | 1 |
| Kishi, Y | 1 |
| Nakamura, H | 1 |
| Bauman, GS | 1 |
| Brett, CM | 1 |
| Ciricillo, SF | 1 |
| Larson, DA | 1 |
| Sneed, P | 1 |
| Staplers, LJ | 1 |
| Edwards, M | 1 |
| Wara, WM | 1 |
| Scher, CS | 1 |
| Amar, D | 1 |
| McDowall, RH | 1 |
| Barst, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Randomized, Controlled Trial to Compare the Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serumserum Biomarkers and on PBMCs in Patients Undergoing Breast Cancer Resection Surgery[NCT03005860] | 0 participants (Actual) | Interventional | 2017-01-01 | Withdrawn (stopped due to Funding could not be arranged, so the study was prematurely terminated) | |||
| A Randomized, Open-label Study to Compare Propofol Anesthesia With Sevoflurane Anesthesia in Terms of Overall Survival in Patients With Surgical Intervention for Either Breast-, Colon- or Rectal Cancer[NCT01975064] | Phase 4 | 5,774 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for propofol and Osteogenic Sarcoma
| Article | Year |
|---|---|
Propofol-based total intravenous anesthesia is associated with better survival than desflurane anesthesia in limb-salvage surgery for osteosarcoma: A retrospective analysis.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Humans; Oste | 2022 |
Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7.
Topics: Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Forkhead Box Protein O1; Glycog | 2021 |
Propofol inhibits proliferation and invasion of osteosarcoma cells by regulation of microRNA-143 expression.
Topics: Anesthetics, Intravenous; Apoptosis; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell S | 2013 |
Propofol suppresses invasion and induces apoptosis of osteosarcoma cell in vitro via downregulation of TGF-β1 expression.
Topics: Apoptosis; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; C | 2016 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Anesthesia for pediatric stereotactic radiosurgery.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Anesthetics, Local; Brain Neoplasms; Bupivacaine; Child | 1998 |
Use of propofol for the prevention of chemotherapy-induced nausea and emesis in oncology patients.
Topics: Adolescent; Adult; Antiemetics; Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Female; Hum | 1992 |