propofol has been researched along with Opioid-Related Disorders in 22 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Opioid-Related Disorders: Disorders related to or resulting from abuse or misuse of OPIOIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The qCON group will adjust intraoperative propofol and remifentanil dosage according to qCON and qNOX values, while the BIS group will adjust according to BIS values and haemodynamic fluctuations." | 3.30 | Effects of qCON and qNOX-guided general anaesthesia management on patient opioid use and prognosis: a study protocol. ( Fang, C; Kang, J; Li, Y; Niu, K; Wang, G; Yu, Y; Yuan, Y; Zheng, Y, 2023) |
| "Sinusoidal rhythms with waxing and waning amplitudes appeared after propofol-induced narcosis but no direct correlations could be determined between individual dosage and characteristic spindle attributes." | 2.72 | Presence of 14Hz spindle oscillations in the human EEG during deep anesthesia. ( Böhler, K; Friedel, C; Hartmann, U; Hensel, M; Kox, WJ; Wolter, S, 2006) |
| "Naloxone treatment, in opioid-addicted patients, induced a marked increase in catecholamine plasma concentrations, metabolism, and cardiovascular stimulation during anesthesia with both propofol and methohexital." | 2.69 | Acute detoxification of opioid-addicted patients with naloxone during propofol or methohexital anesthesia: a comparison of withdrawal symptoms, neuroendocrine, metabolic, and cardiovascular patterns. ( Gastpar, M; Kienbaum, P; Michel, MC; Peters, J; Scherbaum, N; Thürauf, N, 2000) |
| "Societal fears of opioid addiction and lack of advocacy are also causal factors in the under-treatment of pediatric pain." | 2.41 | Pain management in the critically ill child. ( Nichols, DG; Yaster, M, 2001) |
| " Inadequate doses or dosing regimens should be avoided." | 2.39 | Pharmacology of intravenous sedatives and opioids in critically ill patients. ( Levine, RL, 1994) |
| "Propofol is a widely used general anaesthetic with multisite mechanisms and especially ultrashort activation of certain central GABA-A receptors." | 1.35 | A case report of propofol dependence in a physician. ( Bonnet, U; Harkener, J; Scherbaum, N, 2008) |
| "Inflated rates of opioid addiction among anesthesiologists may be caused by chronic exposure to low doses of aerosolized anesthetic/analgesic agents in the operating room." | 1.35 | Fentanyl and propofol exposure in the operating room: sensitization hypotheses and further data. ( Fitzgerald, K; Gold, MS; Goldberger, BA; Kolodner, D; Merlo, LJ, 2008) |
| "Further studies are needed to measure withdrawal symptoms longer than one-day post detoxification and to compare the differences between various detoxification protocols." | 1.33 | Measurement of symptom withdrawal severity in a 24-hour period after the anesthesia-assisted rapid opiate detoxification procedure. ( Chaudry, S; Daiter, J; Herman, S; Raz, B; Teplin, D; Varenbut, M; Whang, P; Yung, M; Zachos, CT, 2005) |
| "Opiate abuse was greater in anesthesiologists and surgeons compared to other specialties." | 1.33 | Second-hand exposure to aerosolized intravenous anesthetics propofol and fentanyl may cause sensitization and subsequent opiate addiction among anesthesiologists and surgeons. ( Bajpai, L; Cendán, JC; Frost-Pineda, K; Gold, MS; Goldberger, BA; McAuliffe, PF; Melker, RJ; Merves, ML; Pomm, RM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, XH | 1 |
| Zhang, SY | 1 |
| Huang, Y | 1 |
| Wang, Q | 1 |
| Zou, L | 1 |
| Zhao, G | 1 |
| Wang, TL | 1 |
| Kang, J | 1 |
| Fang, C | 1 |
| Li, Y | 2 |
| Yuan, Y | 1 |
| Niu, K | 1 |
| Zheng, Y | 1 |
| Yu, Y | 1 |
| Wang, G | 1 |
| Mulier, H | 1 |
| De Frene, B | 1 |
| Benmeridja, L | 1 |
| Vanhoorebeeck, F | 1 |
| Denis, B | 1 |
| Casaer, B | 1 |
| Rogge, FJ | 1 |
| Leleu, K | 1 |
| Mulier, J | 1 |
| Bonnet, U | 1 |
| Harkener, J | 1 |
| Scherbaum, N | 2 |
| Merlo, LJ | 1 |
| Goldberger, BA | 3 |
| Kolodner, D | 1 |
| Fitzgerald, K | 1 |
| Gold, MS | 3 |
| Kovacic, P | 1 |
| Graham, NA | 1 |
| Law, BF | 1 |
| Hettick, JM | 1 |
| Hornsby-Myers, J | 1 |
| Siegel, PD | 1 |
| Maier, C | 1 |
| Leclerc-Springer, J | 1 |
| Teplin, D | 1 |
| Raz, B | 1 |
| Daiter, J | 1 |
| Varenbut, M | 1 |
| Zachos, CT | 1 |
| Whang, P | 1 |
| Herman, S | 1 |
| Chaudry, S | 1 |
| Yung, M | 1 |
| Wolter, S | 2 |
| Friedel, C | 1 |
| Böhler, K | 1 |
| Hartmann, U | 1 |
| Kox, WJ | 2 |
| Hensel, M | 2 |
| McAuliffe, PF | 1 |
| Bajpai, L | 1 |
| Merves, ML | 1 |
| Frost-Pineda, K | 1 |
| Pomm, RM | 1 |
| Melker, RJ | 1 |
| Cendán, JC | 1 |
| Levine, RL | 1 |
| Demaria, PA | 1 |
| Rodgers, C | 1 |
| Braccia, G | 1 |
| Hoffman, WE | 4 |
| Berkowitz, R | 4 |
| McDonald, T | 4 |
| Hass, F | 1 |
| Cook, TM | 1 |
| Collins, PD | 1 |
| Cunningham, F | 1 |
| Cooke, B | 1 |
| Kienbaum, P | 1 |
| Thürauf, N | 1 |
| Michel, MC | 1 |
| Gastpar, M | 1 |
| Peters, J | 1 |
| Yaster, M | 1 |
| Nichols, DG | 1 |
2 reviews available for propofol and Opioid-Related Disorders
| Article | Year |
|---|---|
Pharmacology of intravenous sedatives and opioids in critically ill patients.
Topics: Analgesics, Opioid; Antipsychotic Agents; Barbiturates; Benzodiazepines; Cardiovascular System; Crit | 1994 |
Pain management in the critically ill child.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Child; Child, Preschool; Critical Illness; Fentan | 2001 |
6 trials available for propofol and Opioid-Related Disorders
| Article | Year |
|---|---|
Multimodal Analgesia With Sevoflurane Provides Enhanced Intraoperative Analgesic Effects in Percutaneous Nephrolithotomy: A Randomized, Blinded Clinical Trial.
Topics: Analgesia; Humans; Nephrolithotomy, Percutaneous; Opioid-Related Disorders; Pain, Postoperative; Pro | 2022 |
Effects of qCON and qNOX-guided general anaesthesia management on patient opioid use and prognosis: a study protocol.
Topics: Analgesics, Opioid; Anesthesia, General; Humans; Opioid-Related Disorders; Propofol; Prospective Stu | 2023 |
Presence of 14Hz spindle oscillations in the human EEG during deep anesthesia.
Topics: Adult; Anesthetics, Intravenous; Brain Mapping; Cerebral Cortex; Electroencephalography; Female; Fun | 2006 |
EEG controlled rapid opioid withdrawal under general anaesthesia.
Topics: Anesthesia, General; Anesthetics, Intravenous; Electroencephalography; Female; Humans; Male; Monitor | 2000 |
Acute detoxification of opioid-addicted patients with naloxone during propofol or methohexital anesthesia: a comparison of withdrawal symptoms, neuroendocrine, metabolic, and cardiovascular patterns.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Catecholamines; Female; Humans; Male; Methadon | 2000 |
Combining median electroencephalography frequency and sympathetic activity in an index to evaluate opioid detoxification in patients.
Topics: Electrocardiography; Electroencephalography; Humans; Hypnotics and Sedatives; Naloxone; Narcotic Ant | 2001 |
14 other studies available for propofol and Opioid-Related Disorders
| Article | Year |
|---|---|
Impact of opioid-free anesthesia on complications after deep inferior epigastric perforator flap surgery: A retrospective cohort study.
Topics: Abdominal Wall; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Epigastric Arteries; Femal | 2021 |
A case report of propofol dependence in a physician.
Topics: Adult; Anesthetics, Intravenous; Diagnosis, Differential; Dose-Response Relationship, Drug; Humans; | 2008 |
Fentanyl and propofol exposure in the operating room: sensitization hypotheses and further data.
Topics: Air Pollutants, Occupational; Anesthesiology; Anesthetics, Intravenous; Dose-Response Relationship, | 2008 |
Unifying electron transfer mechanism for addiction involvement by the anesthetic propofol.
Topics: Anesthesiology; Anesthetics; Electron Transport; Electrons; Humans; Models, Biological; Models, Theo | 2010 |
Second-hand and third-hand drug exposures in the operating room: a factor in anesthesiologists' dependency on fentanyl.
Topics: Air Pollutants, Occupational; Anesthesiology; Anesthetics, Inhalation; Anesthetics, Intravenous; Bre | 2010 |
Reservations concerning second-hand fentanyl exposure in the operating room.
Topics: Air Pollutants, Occupational; Anesthetics, Inhalation; Anesthetics, Intravenous; Cross-Sectional Stu | 2010 |
[Life-threatening fentanyl and propofol addiction: interview with a survivor].
Topics: Adult; Analgesics, Opioid; Anesthesiology; Anesthetics, Intravenous; Female; Fentanyl; Humans; Nalox | 2012 |
Measurement of symptom withdrawal severity in a 24-hour period after the anesthesia-assisted rapid opiate detoxification procedure.
Topics: Adult; Anesthetics, Intravenous; Clinical Protocols; Drug Monitoring; Drug Therapy, Combination; Fem | 2005 |
Second-hand exposure to aerosolized intravenous anesthetics propofol and fentanyl may cause sensitization and subsequent opiate addiction among anesthesiologists and surgeons.
Topics: Aerosols; Air Pollutants; Air Pollution; Analgesics, Opioid; Anesthesiology; Anesthetics, Intravenou | 2006 |
Propofol for sedation during rapid opiate detoxification.
Topics: Adult; Clonidine; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Naloxone; Opioid-Re | 1997 |
Ultra-rapid opioid detoxification increases spontaneous ventilation.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Carbon Dioxide; Evaluation Studies as Topic; Huma | 1998 |
Rapid opioid detoxification under anaesthesia.
Topics: Adult; Anesthesia, General; Atracurium; Drug Therapy, Combination; Follow-Up Studies; Gastrointestin | 1998 |
Heart rate variability and plasma catecholamines in patients during opioid detoxification.
Topics: Adult; Analysis of Variance; Anesthetics, Intravenous; Blood Pressure; Electroencephalography; Epine | 1999 |
Median EEG frequency is more sensitive to increases in sympathetic activity than bispectral index.
Topics: Anesthesia, Intravenous; Electroencephalography; Heart Rate; Humans; Naloxone; Opioid-Related Disord | 1999 |