Page last updated: 2024-11-03

propofol and Neuromuscular Diseases

propofol has been researched along with Neuromuscular Diseases in 8 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Neuromuscular Diseases: A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this prospective study was to determine the effects of high-dose propofol on the incidence of fasciculations and myalgia, and to evaluate changes in creatine kinase levels following the administration of succinylcholine in 90 women who underwent laparoscopy."9.10Effects of high-dose propofol on succinylcholine-induced fasciculations and myalgia. ( Kararmaz, A; Kaya, S; Ozyilmaz, MA; Turhanoglu, S, 2003)
"Assessment of cortical SSEP during spine surgery was equally effective and reliable in patients with neuromuscular scoliosis and in patients with idiopathic scoliosis, possibly as a result of propofol-remifentanil anaesthesia."7.74Cortical somatosensory-evoked potentials during spine surgery in patients with neuromuscular and idiopathic scoliosis under propofol-remifentanil anaesthesia. ( Hermanns, H; Jetzek-Zader, M; Krauspe, R; Lipfert, P; Meier, S; Stevens, MF, 2007)
" For the procedure, he was anesthetized with a cumulative intravenous dosage of 700 mg propofol and 0."5.32Transient interruption of unilateral tinnitus by fentanyl and propofol in a patient with neuromuscular disorder. ( Finsterer, J; Gatterer, E; Stöllberger, C, 2004)
"The purpose of this prospective study was to determine the effects of high-dose propofol on the incidence of fasciculations and myalgia, and to evaluate changes in creatine kinase levels following the administration of succinylcholine in 90 women who underwent laparoscopy."5.10Effects of high-dose propofol on succinylcholine-induced fasciculations and myalgia. ( Kararmaz, A; Kaya, S; Ozyilmaz, MA; Turhanoglu, S, 2003)
" We report a case of safe perioperative management with general anesthesia, using total intravenous anesthesia, propofol, fentanyl and a non-depolarizing muscle relaxant but avoiding the use of any inhaled anesthetics or depolarizing muscle relaxants to prevent malignant hyperthermia and postoperative respiratory failure, during anesthetic management for cranioplasty for premature synostosis of the cranial sutures in a pediatric patient of CNMDU1."3.76Anesthetic case in a child with congenital neuromuscular disease with uniform type 1 fibers (CNMDU1). ( Arashi, D; Okutani, R; Tsujii, K, 2010)
"Assessment of cortical SSEP during spine surgery was equally effective and reliable in patients with neuromuscular scoliosis and in patients with idiopathic scoliosis, possibly as a result of propofol-remifentanil anaesthesia."3.74Cortical somatosensory-evoked potentials during spine surgery in patients with neuromuscular and idiopathic scoliosis under propofol-remifentanil anaesthesia. ( Hermanns, H; Jetzek-Zader, M; Krauspe, R; Lipfert, P; Meier, S; Stevens, MF, 2007)
"No unintended anesthesia awareness was noted during the study period."2.80Sedation monitoring during open muscle biopsy in children by Comfort Score and Bispectral Index - a prospective analysis. ( Dohna-Schwake, C; Felderhoff-Müser, U; Müller, O; Schara, U; Tschiedel, E, 2015)
" For the procedure, he was anesthetized with a cumulative intravenous dosage of 700 mg propofol and 0."1.32Transient interruption of unilateral tinnitus by fentanyl and propofol in a patient with neuromuscular disorder. ( Finsterer, J; Gatterer, E; Stöllberger, C, 2004)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dewhirst, E1
Tobias, JD1
Martin, DP1
Tschiedel, E1
Müller, O1
Schara, U1
Felderhoff-Müser, U1
Dohna-Schwake, C1
Okutani, R1
Arashi, D1
Tsujii, K1
Fotopoulou, G1
Theocharis, S1
Vasileiou, I1
Kouskouni, E1
Xanthos, T1
Kararmaz, A1
Kaya, S1
Turhanoglu, S1
Ozyilmaz, MA1
Finsterer, J1
Gatterer, E1
Stöllberger, C1
Inoue, S1
Kawaguchi, M1
Sasaoka, N1
Hirai, K1
Furuya, H1
Hermanns, H1
Lipfert, P1
Meier, S1
Jetzek-Zader, M1
Krauspe, R1
Stevens, MF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does the Choice of Administration Sequence of Propofol and Remifentanil Affect the ED50 and ED95 of Rocuronium for Rapid Sequence Induction of Anesthesia?[NCT02709473]Phase 484 participants (Actual)Interventional2016-03-31Completed
[NCT01695486]30 participants (Actual)Observational2011-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for propofol and Neuromuscular Diseases

ArticleYear
Propofol and remifentanil for rapid sequence intubation in a pediatric patient at risk for aspiration with elevated intracranial pressure.
    Pediatric emergency care, 2013, Volume: 29, Issue:11

    Topics: Anesthesia, Inhalation; Child; Contraindications; Deep Sedation; Emergencies; Headache; Humans; Hypn

2013
Management of the airway without the use of neuromuscular blocking agents: the use of remifentanil.
    Fundamental & clinical pharmacology, 2012, Volume: 26, Issue:1

    Topics: Airway Management; Analgesics, Opioid; Anesthetics, Inhalation; Child; Drug Therapy, Combination; Hu

2012

Trials

2 trials available for propofol and Neuromuscular Diseases

ArticleYear
Sedation monitoring during open muscle biopsy in children by Comfort Score and Bispectral Index - a prospective analysis.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:3

    Topics: Adolescent; Analgesia; Anesthetics, Intravenous; Area Under Curve; Biopsy; Child; Child, Preschool;

2015
Effects of high-dose propofol on succinylcholine-induced fasciculations and myalgia.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:2

    Topics: Adult; Anesthetics, Intravenous; Creatine Kinase; Double-Blind Method; Fasciculation; Female; Gyneco

2003

Other Studies

4 other studies available for propofol and Neuromuscular Diseases

ArticleYear
Anesthetic case in a child with congenital neuromuscular disease with uniform type 1 fibers (CNMDU1).
    Journal of anesthesia, 2010, Volume: 24, Issue:5

    Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Fentanyl; Humans; Hypertensi

2010
Transient interruption of unilateral tinnitus by fentanyl and propofol in a patient with neuromuscular disorder.
    The international tinnitus journal, 2004, Volume: 10, Issue:2

    Topics: Anesthetics, Intravenous; Atrial Flutter; Catheter Ablation; Fentanyl; Heart Atria; Humans; Male; Mi

2004
Effects of neuromuscular block on systemic and cerebral hemodynamics and bispectral index during moderate or deep sedation in critically ill patients.
    Intensive care medicine, 2006, Volume: 32, Issue:3

    Topics: Aged; Anesthesia; Cerebrovascular Circulation; Conscious Sedation; Critical Illness; Electromyograph

2006
Cortical somatosensory-evoked potentials during spine surgery in patients with neuromuscular and idiopathic scoliosis under propofol-remifentanil anaesthesia.
    British journal of anaesthesia, 2007, Volume: 98, Issue:3

    Topics: Adolescent; Adult; Anesthetics, Combined; Anesthetics, Intravenous; Child; Child, Preschool; Diagnos

2007