propofol has been researched along with Nervous System Disorders in 27 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is disagreement about allowing propofol sedation for research magnetic resonance imaging/spectroscopy (MRI/MRS) in children." | 9.11 | Propofol sedation for longitudinal pediatric neuroimaging research. ( Amundsen, LB; Artru, AA; Dager, SR; Dawson, G; Friedman, S; Shaw, DW; Sparks, B, 2005) |
| "To investigate the protective effects of propofol in brain ischemia/reperfusion injury and the role of heme oxygenase-1 (HO-1) in this process." | 7.79 | Propofol attenuates cerebral ischemia/reperfusion injury partially using heme oxygenase-1. ( Cang, J; Liang, C; Wang, H; Xue, Z, 2013) |
| "Adenosine-induced transient flow arrest has been used to facilitate clip ligation of intracranial aneurysms." | 7.76 | Adenosine-induced flow arrest to facilitate intracranial aneurysm clip ligation: dose-response data and safety profile. ( Avram, MJ; Batjer, HH; Bebawy, JF; Bendok, BR; Gupta, DK; Hemmer, LB; Koht, A; Zeeni, C, 2010) |
| "Concerned patients present with Leigh syndrome symptoms or a Leigh-like syndrome." | 5.72 | A Case of ECHS1 Deficiency with Severe Encephalopathy and Status Epilepticus after a Propofol Sedation: Case Report. ( Lutz, S; Paraschaki, G; Preusse, M, 2022) |
| "There is disagreement about allowing propofol sedation for research magnetic resonance imaging/spectroscopy (MRI/MRS) in children." | 5.11 | Propofol sedation for longitudinal pediatric neuroimaging research. ( Amundsen, LB; Artru, AA; Dager, SR; Dawson, G; Friedman, S; Shaw, DW; Sparks, B, 2005) |
| "In order to evaluate the effects of propofol on neurologic outcomes of patients for carotid endarterectomy (CEA), intraoperative monitoring and postoperative complications were evaluated." | 5.10 | [Use of propofol for carotid endarterectomy: its effect on parameters of intraoperative monitoring and clinical outcomes]. ( Hamada, H; Katsuya, C; Matsubara, Y; Nakagawa, I; Sakai, A; Uesugi, F, 2002) |
| "Severe hypotension and bradycardia occur at similar prevalence in neurocritical care patients who receive dexmedetomidine or propofol." | 3.80 | A comparison of severe hemodynamic disturbances between dexmedetomidine and propofol for sedation in neurocritical care patients. ( Doepker, BA; Elijovich, L; Erdman, MJ; Gerlach, AT; Jones, GM; Phillips, GS, 2014) |
| "To investigate the protective effects of propofol in brain ischemia/reperfusion injury and the role of heme oxygenase-1 (HO-1) in this process." | 3.79 | Propofol attenuates cerebral ischemia/reperfusion injury partially using heme oxygenase-1. ( Cang, J; Liang, C; Wang, H; Xue, Z, 2013) |
| "Adenosine-induced transient flow arrest has been used to facilitate clip ligation of intracranial aneurysms." | 3.76 | Adenosine-induced flow arrest to facilitate intracranial aneurysm clip ligation: dose-response data and safety profile. ( Avram, MJ; Batjer, HH; Bebawy, JF; Bendok, BR; Gupta, DK; Hemmer, LB; Koht, A; Zeeni, C, 2010) |
| "Concerned patients present with Leigh syndrome symptoms or a Leigh-like syndrome." | 1.72 | A Case of ECHS1 Deficiency with Severe Encephalopathy and Status Epilepticus after a Propofol Sedation: Case Report. ( Lutz, S; Paraschaki, G; Preusse, M, 2022) |
| "Propofol was given slowly until loss of responsiveness and stopped at the end of surgery." | 1.56 | Patterns of Hysteresis Between Induction and Emergence of Neuroanesthesia Are Present in Spinal and Intracranial Surgeries. ( Amorim, P; Correia, R; Ferreira, AD; Ferreira, AL; Kelz, MB; Mendes, JG; Nunes, CS; Vide, S, 2020) |
| "Ketamine was used in most severe cases." | 1.42 | Preliminary results of the global audit of treatment of refractory status epilepticus. ( Ferlisi, M; Grade, M; Hocker, S; Shorvon, S; Trinka, E, 2015) |
| "Since the outbreak of novel influenza A (H1N1) in 2009, various neurological complications have been cited." | 1.36 | Novel influenza A (H1N1)-associated encephalopathy/encephalitis with severe neurological sequelae and unique image features--a case report. ( Chang, TP; Chen, YC; Lo, CP, 2010) |
| "Propofol is an appropriate agent in neurosurgery, where it represents an alternative to the thiopentone-isoflurane anaesthetic technique." | 1.29 | [Use of Diprivan in neurosurgery]. ( Bruder, N, 1994) |
| "Propofol has been used experimentally in neuroanaesthesia for 4 years, and is now ready to be used on a routine basis in neuroanaesthesia." | 1.28 | [Clinical use of propofol in neuroanesthesia]. ( Chiolero, R; Ravussin, P; Revelly, JP, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 10 (37.04) | 24.3611 |
| 2020's | 4 (14.81) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, ML | 1 |
| Eidam, HA | 1 |
| Paige, M | 1 |
| Jones, PJ | 1 |
| Patel, MK | 1 |
| Preusse, M | 1 |
| Paraschaki, G | 1 |
| Lutz, S | 1 |
| Yao, Y | 1 |
| Sun, Z | 1 |
| Huang, Y | 1 |
| Zhou, X | 1 |
| Xia, D | 1 |
| Nie, Y | 1 |
| Li, S | 1 |
| Yan, T | 1 |
| Ma, Y | 1 |
| Ni, C | 1 |
| Wang, H | 2 |
| Zheng, H | 1 |
| Ferreira, AL | 1 |
| Correia, R | 1 |
| Vide, S | 1 |
| Ferreira, AD | 1 |
| Kelz, MB | 1 |
| Mendes, JG | 1 |
| Nunes, CS | 1 |
| Amorim, P | 1 |
| Liang, C | 1 |
| Cang, J | 1 |
| Xue, Z | 1 |
| González, JA | 1 |
| Llibre Guerra, JC | 1 |
| Prince López, JA | 1 |
| Vázquez Luna, F | 1 |
| Rodríguez Ramos, RM | 1 |
| Ugarte Suárez, JC | 1 |
| Erdman, MJ | 1 |
| Doepker, BA | 1 |
| Gerlach, AT | 1 |
| Phillips, GS | 1 |
| Elijovich, L | 1 |
| Jones, GM | 1 |
| Tan, S | 1 |
| Xu, C | 1 |
| Zhu, W | 1 |
| Willis, J | 1 |
| Seubert, CN | 1 |
| Gravenstein, N | 1 |
| Sumners, C | 1 |
| Martynyuk, AE | 1 |
| Ferlisi, M | 1 |
| Hocker, S | 1 |
| Grade, M | 1 |
| Trinka, E | 1 |
| Shorvon, S | 1 |
| Masters, OW | 1 |
| Bergmans, E | 1 |
| Thies, KC | 1 |
| Patel, P | 1 |
| Sun, L | 1 |
| Bebawy, JF | 1 |
| Gupta, DK | 1 |
| Bendok, BR | 1 |
| Hemmer, LB | 1 |
| Zeeni, C | 1 |
| Avram, MJ | 1 |
| Batjer, HH | 1 |
| Koht, A | 1 |
| Schneemilch, C | 1 |
| Devlin, JW | 1 |
| Mallow-Corbett, S | 1 |
| Riker, RR | 1 |
| Chen, YC | 1 |
| Lo, CP | 1 |
| Chang, TP | 1 |
| Nakagawa, I | 1 |
| Hamada, H | 1 |
| Uesugi, F | 1 |
| Sakai, A | 1 |
| Katsuya, C | 1 |
| Matsubara, Y | 1 |
| Castagnini, HE | 1 |
| van Eijs, F | 1 |
| Salevsky, FC | 1 |
| Nathanson, MH | 1 |
| Lowes, DA | 1 |
| Galley, HF | 1 |
| Lowe, PR | 1 |
| Rikke, BA | 1 |
| Johnson, TE | 1 |
| Webster, NR | 1 |
| Amundsen, LB | 1 |
| Artru, AA | 1 |
| Dager, SR | 1 |
| Shaw, DW | 1 |
| Friedman, S | 1 |
| Sparks, B | 1 |
| Dawson, G | 1 |
| Mehrotra, R | 1 |
| Martorano, PP | 1 |
| Aloj, F | 1 |
| Baietta, S | 1 |
| Fiorelli, A | 1 |
| Munari, M | 1 |
| Paccagnella, F | 1 |
| Rosa, G | 1 |
| Scafuro, M | 1 |
| Zei, E | 1 |
| Falzetti, G | 1 |
| Pelaia, P | 1 |
| Bruder, N | 1 |
| Haberer, JP | 1 |
| Lanigan, C | 1 |
| Sury, M | 1 |
| Bingham, R | 1 |
| Howard, R | 1 |
| Mackersie, A | 1 |
| Ravussin, P | 1 |
| Revelly, JP | 1 |
| Chiolero, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propofol and Nervous System Disorders
| Article | Year |
|---|---|
Adverse drug events associated with the use of analgesics, sedatives, and antipsychotics in the intensive care unit.
Topics: Acidosis; Analgesics; Antipsychotic Agents; Bradycardia; Cardiovascular Diseases; Critical Care; Dru | 2010 |
6 trials available for propofol and Nervous System Disorders
| Article | Year |
|---|---|
Restoration Algorithm-Based Ultrasound Image in Evaluating the Effect of Dexmedetomidine on Patients with Neurological Disorder Anesthetized by Sevoflurane.
Topics: Adult; Algorithms; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Blood Flow Velocity; Carotid A | 2022 |
Feasibility of the superselective test with propofol for determining eloquent brain regions in the endovascular treatment of arteriovenous malformations.
Topics: Adolescent; Adult; Aged; Arteriovenous Malformations; Child; Embolization, Therapeutic; Enbucrilate; | 2013 |
[Use of propofol for carotid endarterectomy: its effect on parameters of intraoperative monitoring and clinical outcomes].
Topics: Aged; Anesthesia; Endarterectomy, Carotid; Evoked Potentials, Somatosensory; Female; Humans; Jugular | 2002 |
Sevoflurane for interventional neuroradiology procedures is associated with more rapid early recovery than propofol.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous | 2004 |
Propofol sedation for longitudinal pediatric neuroimaging research.
Topics: Aging; Anesthetics, Intravenous; Blood Pressure; Child; Child, Preschool; Conscious Sedation; Female | 2005 |
Sufentanil-propofol vs remifentanil-propofol during total intravenous anesthesia for neurosurgery. A multicentre study.
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Female; Human | 2008 |
20 other studies available for propofol and Nervous System Disorders
| Article | Year |
|---|---|
Comparative molecular field analysis and synthetic validation of a hydroxyamide-propofol binding and functional block of neuronal voltage-dependent sodium channels.
Topics: Amides; Anesthetics, Intravenous; Animals; Cells, Cultured; Hippocampus; Inhibitory Concentration 50 | 2009 |
A Case of ECHS1 Deficiency with Severe Encephalopathy and Status Epilepticus after a Propofol Sedation: Case Report.
Topics: Atrophy; Cardiomyopathies; Enoyl-CoA Hydratase; Humans; Infant; Leigh Disease; Lipid Metabolism, Inb | 2022 |
Propofol Attenuates Isoflurane-Induced Neurotoxicity and Cognitive Impairment in Fetal and Offspring Mice.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Animals, Newborn; Brain Chemistry; CA1 R | 2020 |
Patterns of Hysteresis Between Induction and Emergence of Neuroanesthesia Are Present in Spinal and Intracranial Surgeries.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Intraven | 2020 |
Propofol attenuates cerebral ischemia/reperfusion injury partially using heme oxygenase-1.
Topics: Anesthetics, Intravenous; Animals; Apoptosis; Biomarkers; Blotting, Western; Brain Ischemia; Heme Ox | 2013 |
A comparison of severe hemodynamic disturbances between dexmedetomidine and propofol for sedation in neurocritical care patients.
Topics: Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Bradycardia; Critical Care; De | 2014 |
Endocrine and neurobehavioral abnormalities induced by propofol administered to neonatal rats.
Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Behavior, Animal; Brain; Corticosterone; Endocr | 2014 |
Preliminary results of the global audit of treatment of refractory status epilepticus.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Dissociat | 2015 |
Anaesthesia and orphan disease: A child with Congenital Cataract Facial Dysmorphism neuropathy (CCFDN) syndrome: a case report.
Topics: Anesthesia, Intravenous; Cataract; Child; Craniofacial Abnormalities; Humans; Male; Nervous System D | 2017 |
Update on neonatal anesthetic neurotoxicity: insight into molecular mechanisms and relevance to humans.
Topics: Age Factors; Anesthesia; Anesthetics, General; Animals; Apoptosis; Cell Death; Humans; Infant, Newbo | 2009 |
Adenosine-induced flow arrest to facilitate intracranial aneurysm clip ligation: dose-response data and safety profile.
Topics: Adenosine; Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Atri | 2010 |
[General anaesthesia for neurological diseases].
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Autonomic Nervous System; Br | 2010 |
Novel influenza A (H1N1)-associated encephalopathy/encephalitis with severe neurological sequelae and unique image features--a case report.
Topics: Acyclovir; Adult; Anti-Bacterial Agents; Antiviral Agents; Brain; Cerebral Angiography; Electroencep | 2010 |
A microarray analysis of potential genes underlying the neurosensitivity of mice to propofol.
Topics: Anesthetics, Intravenous; Animals; Brain Chemistry; DNA, Complementary; Gene Expression; Mice; Mice, | 2005 |
General anesthesia for a patient with alternating hemiplegia of childhood.
Topics: Abortion, Induced; Adjuvants, Anesthesia; Adult; Anesthesia, General; Anesthetics, Intravenous; Fema | 2005 |
[Use of Diprivan in neurosurgery].
Topics: Anesthesia, Intravenous; Central Nervous System; Humans; Intracranial Pressure; Nervous System Disea | 1994 |
[Premedication and sedation complications during ophthalmic anesthesia].
Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anesthesi | 2000 |
Neurological sequelae in children after prolonged propofol infusion.
Topics: Humans; Infant; Male; Nervous System Diseases; Propofol; Virus Diseases | 1992 |
[Clinical use of propofol in neuroanesthesia].
Topics: Anesthesia, Intravenous; Cerebrovascular Circulation; Craniotomy; Humans; Intracranial Pressure; Ner | 1991 |
Unusual neurological sequelae.
Topics: Adult; Anesthesia, Dental; Anesthesia, Intravenous; Humans; Male; Nervous System Diseases; Postopera | 1990 |