propofol has been researched along with Nerve Pain in 11 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol ameliorates NP and neuroinflammation of rats by up-regulating PPAR γ expression to block the Wnt/β-catenin pathway." | 8.02 | Propofol ameliorates neuropathic pain and neuroinflammation through PPAR γ up-regulation to block Wnt/β-catenin pathway. ( Hou, Z; Jiang, P; Jiang, Q; Luo, D; Yan, Y, 2021) |
| "Propofol ameliorates NP and neuroinflammation of rats by up-regulating PPAR γ expression to block the Wnt/β-catenin pathway." | 4.02 | Propofol ameliorates neuropathic pain and neuroinflammation through PPAR γ up-regulation to block Wnt/β-catenin pathway. ( Hou, Z; Jiang, P; Jiang, Q; Luo, D; Yan, Y, 2021) |
| "It has recently been suggested that propofol exerts a protective effect on the occurrence of persistent pain after breast cancer surgery." | 3.81 | General anaesthetic agents do not influence persistent pain after breast cancer surgery: A prospective nationwide cohort study. ( Albi-Feldzer, A; Bonneau, J; Dualé, C; Dubray, C; Falewee, MN; Lefebvre-Kuntz, D; Nougarède, B; Ouchchane, L; Schoeffler, P; Soule-Sonneville, S, 2015) |
| "Propofol acts as an intravenous anesthetic cure which is widely used as a therapy for the craniocerebral injury that comprised surgical anesthesia as well as the sedation done in the intensive care units." | 1.62 | Propofol Alleviates Neuropathic Pain Induced by Chronic Contractile Injury by Regulating the Spinal glun2b-p38mapkepac1 Pathway. ( Li, W; Qin, C; Yan, J; Yang, Y; You, L; Zhao, Q, 2021) |
| "Propofol-treated CCI rats were also injected with Ad-JAG1 (adenovirus-packaged JAG1 overexpression vector and Ad-NC) to test the role of JAG1 in propofol's analgesic mechanism of action." | 1.62 | Propofol alleviates neuropathic pain in chronic constriction injury rat models via the microRNA-140-3p/Jagged-1 peptide/Notch signaling pathway. ( Chen, Y; Cheng, F; Ma, JX; Qin, W; Yan, FF; Yang, AX, 2021) |
| "In a peripheral nerve ligation model of neuropathic pain, 2,6-DTBP and subhypnotic propofol are antihyperalgesic." | 1.39 | HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain. ( Andersen, OS; Flood, PD; Goldstein, PA; Hemmings, HC; Herold, KF; Proekt, A; Rowley, TJ; Sanford, RL; Tibbs, GR, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Li, W | 1 |
| Qin, C | 1 |
| Yan, J | 1 |
| Zhao, Q | 1 |
| You, L | 1 |
| Yang, Y | 1 |
| Jiang, P | 1 |
| Jiang, Q | 1 |
| Yan, Y | 1 |
| Hou, Z | 1 |
| Luo, D | 1 |
| Cheng, F | 1 |
| Qin, W | 1 |
| Yang, AX | 1 |
| Yan, FF | 1 |
| Chen, Y | 1 |
| Ma, JX | 1 |
| Mandeville, RM | 1 |
| Brown, JM | 1 |
| Gertsch, JH | 1 |
| Allison, DW | 1 |
| Tibbs, GR | 1 |
| Rowley, TJ | 1 |
| Sanford, RL | 1 |
| Herold, KF | 1 |
| Proekt, A | 1 |
| Hemmings, HC | 1 |
| Andersen, OS | 1 |
| Goldstein, PA | 1 |
| Flood, PD | 1 |
| Abdallah, FW | 1 |
| Morgan, PJ | 1 |
| Cil, T | 1 |
| Escallon, JM | 1 |
| Semple, JL | 1 |
| Chan, VW | 1 |
| Lefebvre-Kuntz, D | 1 |
| Dualé, C | 1 |
| Albi-Feldzer, A | 1 |
| Nougarède, B | 1 |
| Falewee, MN | 1 |
| Ouchchane, L | 1 |
| Soule-Sonneville, S | 1 |
| Bonneau, J | 1 |
| Dubray, C | 1 |
| Schoeffler, P | 1 |
| Antkowiak, B | 1 |
| Rudolph, U | 1 |
| Fuzier, R | 1 |
| Puel, F | 1 |
| Izard, P | 1 |
| Sommet, A | 1 |
| Pierre, S | 1 |
| Yoshimura, M | 1 |
| Furue, H | 1 |
| Takazawa, T | 1 |
| Kohno, T | 1 |
| Takeshima, K | 1 |
| Canavero, S | 1 |
| Bonicalzi, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Etude épidémiologique Multicentrique Des Douleurs Neuropathiques Post-opératoires[NCT00812734] | 3,322 participants (Actual) | Observational | 2006-04-30 | Completed | |||
| The Effects of Anesthetics on Persistent Pain Following Breast Cancer Surgery[NCT03782896] | 89 participants (Actual) | Observational | 2018-12-31 | Completed | |||
| Evaluation of Pain and Postoperative Nausea Vomiting Incidence in Outpatient Surgery at IUCT-Oncopole Hospital[NCT03669328] | 200 participants (Actual) | Observational [Patient Registry] | 2016-06-01 | Completed | |||
| Prospective Cohort Study Assessing Chronic Pain in Patients With Thoracic Blocks Following Minor Surgery for Breast Cancer.[NCT03912948] | 205 participants (Actual) | Observational | 2019-04-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propofol and Nerve Pain
| Article | Year |
|---|---|
New insights in the systemic and molecular underpinnings of general anesthetic actions mediated by γ-aminobutyric acid A receptors.
Topics: Anesthesia, General; Anesthetics, General; Brain Injuries; GABAergic Neurons; Hippocampus; Humans; I | 2016 |
[Function of spinal GABA receptor and its modulation].
Topics: Anesthetics, Intravenous; Animals; Benzodiazepines; gamma-Aminobutyric Acid; Humans; Neuralgia; Patc | 2007 |
1 trial available for propofol and Nerve Pain
| Article | Year |
|---|---|
Comparing the DN4 tool with the IASP grading system for chronic neuropathic pain screening after breast tumor resection with and without paravertebral blocks: a prospective 6-month validation study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Female; Humans; Hypnotics and Sedative | 2015 |
8 other studies available for propofol and Nerve Pain
| Article | Year |
|---|---|
Propofol Alleviates Neuropathic Pain Induced by Chronic Contractile Injury by Regulating the Spinal glun2b-p38mapkepac1 Pathway.
Topics: Anesthetics, Intravenous; Animals; Computational Biology; Disease Models, Animal; Ganglia, Spinal; G | 2021 |
Propofol ameliorates neuropathic pain and neuroinflammation through PPAR γ up-regulation to block Wnt/β-catenin pathway.
Topics: Anesthetics, Intravenous; Animals; Inflammation; Male; Neuralgia; PPAR gamma; Propofol; Rats; Rats, | 2021 |
Propofol alleviates neuropathic pain in chronic constriction injury rat models via the microRNA-140-3p/Jagged-1 peptide/Notch signaling pathway.
Topics: Animals; Constriction; Jagged-1 Protein; MicroRNAs; Neuralgia; Propofol; Rats; Rats, Sprague-Dawley; | 2021 |
Use of Posterior Root-Muscle Reflexes in Peripheral Nerve Surgery: A Case Report.
Topics: Anesthesia, General; Anesthetics, General; Decompression, Surgical; Electric Stimulation; Evoked Pot | 2016 |
HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.
Topics: Algorithms; Anesthetics; Anesthetics, Intravenous; Animals; Behavior, Animal; Biological Availabilit | 2013 |
General anaesthetic agents do not influence persistent pain after breast cancer surgery: A prospective nationwide cohort study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, General; Breast Neoplasms; Cohort Studies; Female; Ho | 2015 |
General anaesthetic agents do not influence persistent pain after breast cancer surgery: A prospective nationwide cohort study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, General; Breast Neoplasms; Cohort Studies; Female; Ho | 2015 |
General anaesthetic agents do not influence persistent pain after breast cancer surgery: A prospective nationwide cohort study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, General; Breast Neoplasms; Cohort Studies; Female; Ho | 2015 |
General anaesthetic agents do not influence persistent pain after breast cancer surgery: A prospective nationwide cohort study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, General; Breast Neoplasms; Cohort Studies; Female; Ho | 2015 |
Prospective cohort study assessing chronic pain in patients following minor surgery for breast cancer.
Topics: Aged; Analgesia; Anesthesia, General; Breast Neoplasms; Chronic Pain; Female; Humans; Lymph Node Exc | 2017 |
Prospective cohort study assessing chronic pain in patients following minor surgery for breast cancer.
Topics: Aged; Analgesia; Anesthesia, General; Breast Neoplasms; Chronic Pain; Female; Humans; Lymph Node Exc | 2017 |
Prospective cohort study assessing chronic pain in patients following minor surgery for breast cancer.
Topics: Aged; Analgesia; Anesthesia, General; Breast Neoplasms; Chronic Pain; Female; Humans; Lymph Node Exc | 2017 |
Prospective cohort study assessing chronic pain in patients following minor surgery for breast cancer.
Topics: Aged; Analgesia; Anesthesia, General; Breast Neoplasms; Chronic Pain; Female; Humans; Lymph Node Exc | 2017 |
Reversible central pain.
Topics: Cysts; Female; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Middle Aged; Neuralgia; | 2001 |