Page last updated: 2024-11-03

propofol and Muscle Relaxation

propofol has been researched along with Muscle Relaxation in 55 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"We investigated the continuous infusion rates of rocuronium necessary to obtain the surgical muscle relaxation before, during, and after the Pringle maneuver on patients who underwent hepatectomy."9.27The Pringle maneuver reduces the infusion rate of rocuronium required to maintain surgical muscle relaxation during hepatectomy. ( Kajiura, A; Nagata, O; Sanui, M, 2018)
"This study was conducted to compare recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex with succinylcholine during electroconvulsive therapy (ECT)."7.77Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy. ( Hoshi, H; Kadoi, Y; Nishida, A; Saito, S, 2011)
"The purpose of this study was to determine the optimum bolus dose of propofol required to provide excellent conditions for tracheal intubation following inhalational induction of anaesthesia using 5% sevoflurane without neuromuscular blockade."7.77Optimum bolus dose of propofol for tracheal intubation during sevoflurane induction without neuromuscular blockade in children. ( Hong, JY; Jeong, SM; Kim, SH; Park, PH; Suk, EH, 2011)
" Although its mechanism of smooth muscle relaxation is unknown, propofol has been associated with less bronchoconstriction during anaesthetic induction."7.74Investigation of the relaxant effects of propofol on ovalbumin-induced asthma in guinea pigs. ( Bagcivan, I; Cevit, O; Gursoy, S; Kaya, T; Mimaroglu, C; Yildirim, MK; Yildirim, S, 2007)
"Propofol is a sedative and a hypnotic agent used in the induction and maintenance of general anesthesia."5.56Spastic Cerebral Palsy Pain Improvement With Propofol: A Case Report. ( Guichard, L; Lansaman, T; Martinez, V, 2020)
"Rocuronium bromide (Rb) is a rapid onset, intermediate-acting neuromuscular blocking agent that is suitable for continuous administration."5.42Effective method of continuous rocuronium administration based on effect-site concentrations using a pharmacokinetic/pharmacodynamic model during propofol-remifentanil anesthesia. ( Enohata, K; Kamikawaji, T; Kanmura, Y; Matsunaga, A; Moriyama, T; Nagata, O; Uchino, E, 2015)
" The dosage of propofol needed for induction, consumption during maintenance and recovery time were recorded."5.40Impact of malnutrition on propofol consumption and recovery time among patients undergoing laparoscopic gastrointestinal surgery. ( Bu, H; Fan, Y; Gao, F; Manyande, A; Tian, X; Tian, Y; Xiang, Y; Yang, H, 2014)
"Propofol pretreatment increased MCh relaxation in arteries from captopril-treated compared with untreated rats (P = 0."5.39Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril. ( Bourque, SL; Davidge, ST; Gragasin, FS, 2013)
"Airway smooth muscle contraction is not caused by the increase in intracellular Ca(2+) ([Ca(2+)](i)) alone because agonist stimulation increases tension at the same [Ca(2+)](i) (increase in Ca(2+) sensitivity)."5.35Rho-kinase inhibitors augment the inhibitory effect of propofol on rat bronchial smooth muscle contraction. ( Chiba, Y; Hanazaki, M; Kohjitani, A; Misawa, M; Morita, K; Sakai, H; Yokoyama, M, 2008)
"We investigated the continuous infusion rates of rocuronium necessary to obtain the surgical muscle relaxation before, during, and after the Pringle maneuver on patients who underwent hepatectomy."5.27The Pringle maneuver reduces the infusion rate of rocuronium required to maintain surgical muscle relaxation during hepatectomy. ( Kajiura, A; Nagata, O; Sanui, M, 2018)
"Both sevoflurane and propofol at low dosages combined with remifentanil under comparable BIS values and partial muscle relaxation can be used when monitoring of TceMEPs and SSEPs is required for brainstem surgery."5.20Comparison of the Effects of Propofol and Sevoflurane Combined With Remifentanil on Transcranial Electric Motor-evoked and Somatosensory-evoked Potential Monitoring During Brainstem Surgery. ( Doménech-Asensi, P; Falcón-Araña, L; Fuentes-García, D; Hernández-Palazón, J; Izura, V; Piqueras-Pérez, C, 2015)
" This study hypothesized that intracoelomic administration of a new anesthetic, fospropofol, in turtles would result in dose-dependent anesthesia and respiratory depression."5.17The efficacy of intracoelomic fospropofol in red-eared sliders (Trachemys scripta elegans). ( Johnson, RA; Schroeder, CA, 2013)
" with Steyn modification which includes five criteria; ease of laryngoscopy, degree of coughing, position of vocal cords, jaw relaxation, and limb movement and graded on a 4-point scale."5.12Comparative evaluation of different doses of propofol preceded by fentanyl on intubating conditions and pressor response during tracheal intubation without muscle relaxants. ( Gupta, A; Kale, S; Kaur, R; Malhotra, R, 2006)
" Muscle relaxation was provided by cisatracurium."5.09Effect of bolus dose of remifentanil on haemodynamic response to tracheal intubation. ( Barclay, K; Kluger, MT, 2000)
" During this period of apnea, abdominal and thoracic girth was assessed with noninvasive RIP."3.79Abdominal relaxation during emergence from general anesthesia with propofol and remifentanil. ( Atkins, JH; Mandel, JE, 2013)
"This study was conducted to compare recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex with succinylcholine during electroconvulsive therapy (ECT)."3.77Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy. ( Hoshi, H; Kadoi, Y; Nishida, A; Saito, S, 2011)
"The purpose of this study was to determine the optimum bolus dose of propofol required to provide excellent conditions for tracheal intubation following inhalational induction of anaesthesia using 5% sevoflurane without neuromuscular blockade."3.77Optimum bolus dose of propofol for tracheal intubation during sevoflurane induction without neuromuscular blockade in children. ( Hong, JY; Jeong, SM; Kim, SH; Park, PH; Suk, EH, 2011)
" Although its mechanism of smooth muscle relaxation is unknown, propofol has been associated with less bronchoconstriction during anaesthetic induction."3.74Investigation of the relaxant effects of propofol on ovalbumin-induced asthma in guinea pigs. ( Bagcivan, I; Cevit, O; Gursoy, S; Kaya, T; Mimaroglu, C; Yildirim, MK; Yildirim, S, 2007)
"We investigated the effect of two IV anesthetics, propofol and etomidate, on airway responsiveness in a rat model of chronic hypoxia (CH) in comparison with normoxic rats."3.72The effects of propofol and etomidate on airway contractility in chronically hypoxic rats. ( Marthan, R; Ouédraogo, N; Roux, E, 2003)
" The tracheas were intubated after fentanyl/propofol without the aid of muscle relaxation."3.70Surface vs intramuscular laryngeal electromyography. ( Hemmerling, TM; Jacobi, KE; Schmidt, J; Wolf, SR; Wolf, T, 2000)
"Sleep or muscle relaxation were achieved within 60 seconds in both groups, but time to achieve successful intubation was more than twice as fast with propofol (120 vs 260 seconds)."2.73Propofol compared with the morphine, atropine, and suxamethonium regimen as induction agents for neonatal endotracheal intubation: a randomized, controlled trial. ( Abdel-Latif, ME; Awad, J; Ghanta, S; Lui, K; Oei, J; Ravindranathan, H, 2007)
"Remifentanil consumption was 0."2.73Muscle relaxation does not influence venous oxygen saturation during cardiopulmonary bypass. ( Cammu, G; Cardinael, S; Coddens, J; Deloof, T; Eecke, GV; Foubert, L; Gooris, T; Lahousse, S, 2007)
" We conclude that a bolus dosage of 0."2.68Mivacurium chloride for short laparoscopic procedures. ( Fraselle, B; Laloyaux, P; Pendeville, PE; Van Boven, MJ, 1995)
"Alfentanil 15 mu g/kg was not statistically significantly different from saline (P = 0."2.68Intubation without muscle relaxant: an alternative technique for rapid tracheal intubation. ( Teoh, GS; Wong, AK, 1996)
"The presence of gagging, coughing, laryngospasm and movement was noted and graded."2.67Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone. ( Carey, M; Kirby, F; Power, M; Scanlon, P, 1993)
"Propofol is a sedative and a hypnotic agent used in the induction and maintenance of general anesthesia."1.56Spastic Cerebral Palsy Pain Improvement With Propofol: A Case Report. ( Guichard, L; Lansaman, T; Martinez, V, 2020)
"Rocuronium bromide (Rb) is a rapid onset, intermediate-acting neuromuscular blocking agent that is suitable for continuous administration."1.42Effective method of continuous rocuronium administration based on effect-site concentrations using a pharmacokinetic/pharmacodynamic model during propofol-remifentanil anesthesia. ( Enohata, K; Kamikawaji, T; Kanmura, Y; Matsunaga, A; Moriyama, T; Nagata, O; Uchino, E, 2015)
" The dosage of propofol needed for induction, consumption during maintenance and recovery time were recorded."1.40Impact of malnutrition on propofol consumption and recovery time among patients undergoing laparoscopic gastrointestinal surgery. ( Bu, H; Fan, Y; Gao, F; Manyande, A; Tian, X; Tian, Y; Xiang, Y; Yang, H, 2014)
"Propofol pretreatment increased MCh relaxation in arteries from captopril-treated compared with untreated rats (P = 0."1.39Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril. ( Bourque, SL; Davidge, ST; Gragasin, FS, 2013)
"The acepromazine was administered in the left thoracic member and the propofol in the cervical vertebral sinus."1.38Association of acepromazine with propofol in giant Amazon turtles Podocnemis expansa reared in captivity. ( Alves-Júnior, JR; Andrade, MB; Bosso, AC; Jayme, Vde S; Santos, AL; Werther, K, 2012)
"Airway smooth muscle contraction is not caused by the increase in intracellular Ca(2+) ([Ca(2+)](i)) alone because agonist stimulation increases tension at the same [Ca(2+)](i) (increase in Ca(2+) sensitivity)."1.35Rho-kinase inhibitors augment the inhibitory effect of propofol on rat bronchial smooth muscle contraction. ( Chiba, Y; Hanazaki, M; Kohjitani, A; Misawa, M; Morita, K; Sakai, H; Yokoyama, M, 2008)
"Mivacurium was used for neuromuscular blockade."1.34Clinical validation of electromyography and acceleromyography as sensors for muscle relaxation. ( Hänzi, P; Lauber, R; Leibundgut, D; Wessendorf, R; Zbinden, AM, 2007)
"Propofol is an excellent anesthetic for patients with hyperreactive airways in which the epithelial layer is damaged."1.30The relaxant effect of propofol on guinea pig tracheal muscle is independent of airway epithelial function and beta-adrenoceptor activity. ( Hashiba, E; Hashimoto, Y; Hirota, K; Matsuki, A; Sato, T, 1999)
" Optimal length was determined, a dose-response curve to acetylcholine was established, and the 50% effective dose (ED50) of acetylcholine was calculated."1.29Direct relaxant effects of intravenous anesthetics on airway smooth muscle. ( Bosnjak, ZJ; Cheng, EY; Coon, RL; Kampine, JP; Mazzeo, AJ, 1996)
"Propofol anaesthesia was characterised by smooth rapid induction and good muscle relaxation but was only of short duration, ranging from two to seven minutes, and seemed to cause a marked respiratory depression."1.28Preliminary studies on the use of propofol in the domestic pigeon (Columba livia). ( Cooper, JE; Fitzgerald, G, 1990)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.82)18.7374
1990's18 (32.73)18.2507
2000's22 (40.00)29.6817
2010's13 (23.64)24.3611
2020's1 (1.82)2.80

Authors

AuthorsStudies
Martinez, V1
Lansaman, T1
Guichard, L1
Kajiura, A2
Nagata, O3
Sanui, M1
Gragasin, FS1
Bourque, SL1
Davidge, ST1
Schroeder, CA1
Johnson, RA1
Takizawa, Y1
Nakatomi, T1
Kodera, S1
Murayama, T1
Tian, X1
Xiang, Y1
Fan, Y1
Bu, H1
Yang, H1
Manyande, A1
Gao, F1
Tian, Y1
Hernández-Palazón, J1
Izura, V1
Fuentes-García, D1
Piqueras-Pérez, C1
Doménech-Asensi, P1
Falcón-Araña, L1
Moriyama, T1
Matsunaga, A1
Enohata, K1
Kamikawaji, T1
Uchino, E1
Kanmura, Y2
El-Orbany, M1
Gallos, G2
Gleason, NR2
Virag, L1
Zhang, Y2
Mizuta, K1
Whittington, RA1
Emala, CW2
Narayanaswamy, M1
Kadoi, Y1
Hoshi, H1
Nishida, A1
Saito, S1
Kim, SH1
Hong, JY1
Suk, EH1
Jeong, SM1
Park, PH1
Aissaoui, Y1
Qamous, Y1
Serghini, I1
Zoubir, M1
Salim, JL1
Boughalem, M1
Alves-Júnior, JR1
Bosso, AC1
Andrade, MB1
Jayme, Vde S1
Werther, K1
Santos, AL1
Atkins, JH1
Mandel, JE1
Jabbour-Khoury, SI1
Dabbous, AS1
Rizk, LB1
Abou Jalad, NM1
Bartelmaos, TE1
El-Khatib, MF1
Baraka, AS1
Ouédraogo, N1
Marthan, R1
Roux, E1
Fodale, V1
Praticò, C1
Santamaria, LB1
Vasella, FC1
Frascarolo, P1
Spahn, DR1
Magnusson, L1
Massó, E1
Sabaté, S1
Hinojosa, M1
Vila, P1
Canet, J1
Langeron, O1
Gupta, A1
Kaur, R1
Malhotra, R1
Kale, S1
Nagahama, S1
Nishimura, R1
Mochizuki, M1
Sasaki, N1
Goldmann, K1
Hoch, N1
Wulf, H1
Hänzi, P1
Leibundgut, D1
Wessendorf, R1
Lauber, R1
Zbinden, AM1
Cammu, G1
Cardinael, S1
Lahousse, S1
Eecke, GV1
Coddens, J1
Foubert, L1
Gooris, T1
Deloof, T1
Ghanta, S1
Abdel-Latif, ME1
Lui, K1
Ravindranathan, H1
Awad, J1
Oei, J1
Bagcivan, I2
Cevit, O1
Yildirim, MK2
Gursoy, S2
Yildirim, S2
Kaya, T2
Mimaroglu, C2
Kaya Temiz, T1
Yilmaz, A1
Turan, M1
Petrovski, J1
Hanazaki, M2
Yokoyama, M1
Morita, K1
Kohjitani, A1
Sakai, H1
Chiba, Y1
Misawa, M1
Miyawaki, I1
Nakamura, K1
Terasako, K1
Toda, H1
Kakuyama, M1
Mori, K1
Utkan, T1
Kafali, H1
Sarioglu, Y1
Scanlon, P1
Carey, M1
Power, M1
Kirby, F1
Pedersen, CM1
Thirstrup, S1
Nielsen-Kudsk, JE1
Hofmockel, R1
Benad, G1
Cheng, EY1
Mazzeo, AJ1
Bosnjak, ZJ1
Coon, RL1
Kampine, JP2
Pendeville, PE1
Laloyaux, P1
Fraselle, B1
Van Boven, MJ1
Wong, AK1
Teoh, GS1
Kelicen, P1
Ismailoglu, UB1
Erdemli, O1
Sahin-Erdemli, I1
Moreno, L1
Martínez-Cuesta, MA1
Muedra, V1
Beltrán, B1
Esplugues, J1
Wallerstedt, SM1
Törnebrandt, K1
Bodelsson, M1
van Dongen, EP1
ter Beek, HT1
Schepens, MA1
Morshuis, WJ1
Langemeijer, HJ1
Kalkman, CJ1
Boezeman, EH1
Hashiba, E1
Sato, T1
Hirota, K1
Hashimoto, Y1
Matsuki, A1
Yamashita, A1
Kajikuri, J1
Ohashi, M1
Itoh, T1
Jones, KA1
Warner, DO1
Barclay, K1
Kluger, MT1
Hemmerling, TM1
Schmidt, J1
Wolf, T1
Wolf, SR1
Jacobi, KE1
Tan, CH1
Onisong, MK1
Chiu, WK1
Coughlan, MG1
Flynn, NM1
Kenny, D1
Warltier, DC1
Wilder-Smith, OH1
Borgeat, A1
Boisson-Bertrand, D1
Taron, F1
Laxenaire, MC1
Fitzgerald, G1
Cooper, JE1
Bentley, GN1
Gent, JP1
Goodchild, CS1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind, Randomized, Crossover Design Study To Compare The Rocuronium Reversal By Sugammadex To Succinylcholine For Electroconvulsive Therapy (ECT)[NCT03532178]Phase 244 participants (Actual)Interventional2019-01-01Completed
Bispectral Index Monitoring In Pediatric Cataract Surgery: A Comparative Study Using Propofol- Midazolam Versus Sevoflurane Anesthesia[NCT05262205]100 participants (Anticipated)Interventional2021-11-15Enrolling by invitation
Pilot Study of EEG Signs of Awakening Secondary to Injection of Sugammadex: Evaluation by Recording Bispectral Index and NeuroSENSE (Prospective, Double-blind Study)[NCT01161004]Phase 450 participants (Actual)Interventional2010-09-30Completed
Respiratory Effect of the LISA (Less Invasive Surfactant Administration) Method With Sedation by Propofol Versus Absence of Sedation: Double-blind Comparative Randomized Clinical Trial.[NCT04016246]Phase 3542 participants (Anticipated)Interventional2019-10-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Recovery Time of T1 to 90% Baseline

The time of neuromuscular recovery from sugammadex 4mg/kg dose reversal rocuronium at 0.6 mg/kg compared with traditionally used succinylcholine in electroconvulsive therapy (ECT). (NCT03532178)
Timeframe: 30 minutes

Interventionminutes (Mean)
Muscle Relaxant #16.79
Muscle Relaxant #210.97

Number of Participants With Treatment or Emergent Adverse Events of the Drugs

To document the side-effect profiles of sugammadex reversal of rocuronium and succhinylcholine in the ECT patient population (NCT03532178)
Timeframe: 24 hours after the procedure

,
InterventionParticipants (Count of Participants)
NauseaMyalgiaHeadache
Rocuronium + Sugammadex117
Succinylcholine + Normal Saline329

Trials

18 trials available for propofol and Muscle Relaxation

ArticleYear
The Pringle maneuver reduces the infusion rate of rocuronium required to maintain surgical muscle relaxation during hepatectomy.
    Journal of anesthesia, 2018, Volume: 32, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, General; Female; Hepatectomy; Humans; Int

2018
The efficacy of intracoelomic fospropofol in red-eared sliders (Trachemys scripta elegans).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2013, Volume: 44, Issue:4

    Topics: Anesthesia; Animals; Cross-Over Studies; Drug Administration Routes; Hypnotics and Sedatives; Muscle

2013
Comparison of the Effects of Propofol and Sevoflurane Combined With Remifentanil on Transcranial Electric Motor-evoked and Somatosensory-evoked Potential Monitoring During Brainstem Surgery.
    Journal of neurosurgical anesthesiology, 2015, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Brain Stem; Consciousnes

2015
Magnesium sulphate: an adjuvant to tracheal intubation without muscle relaxation--a randomised study.
    European journal of anaesthesiology, 2012, Volume: 29, Issue:8

    Topics: Adjuvants, Anesthesia; Adult; Analysis of Variance; Anesthesia, General; Anesthetics, Intravenous; C

2012
A combination of alfentanil-lidocaine-propofol provides better intubating conditions than fentanyl-lidocaine-propofol in the absence of muscle relaxants.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:2

    Topics: Adult; Alfentanil; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Blood Pressure;

2003
Antagonism of neuromuscular blockade but not muscle relaxation affects depth of anaesthesia.
    British journal of anaesthesia, 2005, Volume: 94, Issue:6

    Topics: Adult; Aged; Anesthetics, Combined; Anesthetics, Intravenous; Atracurium; Blood Pressure; Cholineste

2005
Lightwand tracheal intubation with and without muscle relaxation.
    Anesthesiology, 2006, Volume: 104, Issue:2

    Topics: Adult; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Electrocardiography; Female; Fib

2006
Comparative evaluation of different doses of propofol preceded by fentanyl on intubating conditions and pressor response during tracheal intubation without muscle relaxants.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:4

    Topics: Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Child; Child, Preschool; Cough; Doubl

2006
The effects of propofol, isoflurane and sevoflurane on vecuronium infusion rates for surgical muscle relaxation in dogs.
    Veterinary anaesthesia and analgesia, 2006, Volume: 33, Issue:3

    Topics: Anesthesia, General; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Cross-Over Studies; D

2006
Muscle relaxation does not influence venous oxygen saturation during cardiopulmonary bypass.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:2

    Topics: Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Atracurium; Cardiopulmonary Bypass; Elec

2007
Propofol compared with the morphine, atropine, and suxamethonium regimen as induction agents for neonatal endotracheal intubation: a randomized, controlled trial.
    Pediatrics, 2007, Volume: 119, Issue:6

    Topics: Atropine; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infant

2007
Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:9

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Cough; Extremities; Female; Gagging; Head; H

1993
Time-course of action and intubating conditions with rocuronium bromide under propofol-alfentanil anaesthesia.
    European journal of anaesthesiology. Supplement, 1995, Volume: 11

    Topics: Adult; Alfentanil; Androstanols; Anesthesia; Anesthetics, Intravenous; Electric Stimulation; Electro

1995
Mivacurium chloride for short laparoscopic procedures.
    Acta anaesthesiologica Belgica, 1995, Volume: 46, Issue:3-4

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Female; Humans;

1995
Intubation without muscle relaxant: an alternative technique for rapid tracheal intubation.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Alfentanil; Anesthetics, Intravenous; Cough; Double-Blind Method; Elective Surgic

1996
Effect of bolus dose of remifentanil on haemodynamic response to tracheal intubation.
    Anaesthesia and intensive care, 2000, Volume: 28, Issue:4

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracurium; Dose-Response Relationship, Dr

2000
The influence of induction technique on intubating conditions 1 min after rocuronium administration: a comparison of a propofol-ephedrine combination and propofol.
    Anaesthesia, 2002, Volume: 57, Issue:3

    Topics: Adult; Androstanols; Anesthetics, Intravenous; Blood Pressure; Diaphragm; Double-Blind Method; Drug

2002
Etomidate vs. propofol to carry out suspension laryngoscopies.
    European journal of anaesthesiology, 1991, Volume: 8, Issue:2

    Topics: Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthesia, Local; Apnea; Conscious

1991

Other Studies

37 other studies available for propofol and Muscle Relaxation

ArticleYear
Spastic Cerebral Palsy Pain Improvement With Propofol: A Case Report.
    A&A practice, 2020, Volume: 14, Issue:7

    Topics: Adult; Analgesics; Anesthetics, Intravenous; Cerebral Palsy; Humans; Hypnotics and Sedatives; Male;

2020
Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:4

    Topics: Aging; Anesthetics, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Animals; Area Under Curve

2013
A large individual variation in both the infusion rate and the blood concentration of rocuronium necessary for obtain adequate surgical muscle relaxation during total intravenous anesthesia with propofol and remifentanil.
    Journal of anesthesia, 2015, Volume: 29, Issue:1

    Topics: Adult; Aged; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Humans; Laparo

2015
Impact of malnutrition on propofol consumption and recovery time among patients undergoing laparoscopic gastrointestinal surgery.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Accelerometry; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Intravenous; Anest

2014
Effective method of continuous rocuronium administration based on effect-site concentrations using a pharmacokinetic/pharmacodynamic model during propofol-remifentanil anesthesia.
    Journal of anesthesia, 2015, Volume: 29, Issue:4

    Topics: Adult; Aged; Androstanols; Anesthesia; Female; Humans; Male; Middle Aged; Muscle Relaxation; Neuromu

2015
Laryngeal injuries and tracheal intubating conditions with or without muscular relaxation II.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:3

    Topics: Anesthetics, Intravenous; Atracurium; Humans; Intubation, Intratracheal; Larynx; Monitoring, Intraop

2009
Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation.
    Anesthesiology, 2009, Volume: 110, Issue:4

    Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Chromatography, High Pressure Liquid; Dose-Respons

2009
Decrease in Bispectral Index while correcting hyperglycemia and an increase in Bispectral Index with correction of hypoglycemia.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:3

    Topics: Aged; Anesthesia; Anesthesiology; Blood Glucose; Electroencephalography; Female; Fentanyl; Humans; H

2009
Propofol preferentially relaxes neurokinin receptor-2-induced airway smooth muscle contraction in guinea pig trachea.
    Anesthesiology, 2010, Volume: 112, Issue:6

    Topics: Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Re

2010
Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: Androstanols; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Electroconv

2011
Optimum bolus dose of propofol for tracheal intubation during sevoflurane induction without neuromuscular blockade in children.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:5

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Child; Child, Preschool; Dose-Res

2011
Association of acepromazine with propofol in giant Amazon turtles Podocnemis expansa reared in captivity.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:8

    Topics: Acepromazine; Anesthesia; Anesthetics, Combined; Animals; Brazil; Female; Locomotion; Male; Muscle R

2012
Abdominal relaxation during emergence from general anesthesia with propofol and remifentanil.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:2

    Topics: Abdominal Muscles; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Combined; Anest

2013
The effects of propofol and etomidate on airway contractility in chronically hypoxic rats.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:4

    Topics: Algorithms; Anesthetics, Intravenous; Animals; Chronic Disease; Dose-Response Relationship, Drug; Dr

2003
Coadministration of propofol and midazolam decreases bispectral index value as a result of synergic muscle relaxant action on the motor system.
    Anesthesiology, 2004, Volume: 101, Issue:3

    Topics: Anesthetics, Intravenous; Drug Synergism; Electroencephalography; Humans; Midazolam; Muscle Relaxati

2004
[Influence of neuromuscular blockade on the airway leak pressure of the ProSeal laryngeal mask airway].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2006, Volume: 41, Issue:4

    Topics: Adult; Aged; Air Pressure; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Female;

2006
Clinical validation of electromyography and acceleromyography as sensors for muscle relaxation.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:10

    Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Electric Stim

2007
Investigation of the relaxant effects of propofol on ovalbumin-induced asthma in guinea pigs.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:9

    Topics: Animals; Asthma; Calcium Channels; Disease Models, Animal; Guinea Pigs; Hypnotics and Sedatives; Iso

2007
Investigation of relaxant effects of propofol on sheep sphincter of Oddi.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2007, Volume: 7, Issue:2-3

    Topics: 4-Aminopyridine; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Combinati

2007
Partially occluded carbon dioxide absorber due to incorrect filling technique.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:2

    Topics: Adult; Androstanols; Anesthesia, Inhalation; Anesthetics, Intravenous; Carbon Dioxide; Cholecystecto

2008
Rho-kinase inhibitors augment the inhibitory effect of propofol on rat bronchial smooth muscle contraction.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Amides; Animals; Bronchi; Bronchoconst

2008
Modification of endothelium-dependent relaxation by propofol, ketamine, and midazolam.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:3

    Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Binding Sites; Cyclic GMP; Endothelium, Vascular;

1995
Effects of propofol on vascular smooth muscle function in isolated rat aorta.
    Methods and findings in experimental and clinical pharmacology, 1994, Volume: 16, Issue:4

    Topics: Acetylcholine; Animals; Aorta; Drug Interactions; Female; Male; Muscle Contraction; Muscle Relaxatio

1994
Smooth muscle relaxant effects of propofol and ketamine in isolated guinea-pig trachea.
    European journal of pharmacology, 1993, Jul-06, Volume: 238, Issue:1

    Topics: Animals; Carbachol; Dinoprost; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; In

1993
Direct relaxant effects of intravenous anesthetics on airway smooth muscle.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:1

    Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Bronchi; Calcium; Dogs; Dose-Response Relationship

1996
The effect of propofol and thiopentone on impairment by reactive oxygen species of endothelium-dependent relaxation in rat aortic rings.
    European journal of anaesthesiology, 1997, Volume: 14, Issue:3

    Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Aorta, Thoracic; Endothelium, Vascular; Etomidate;

1997
Role of the endothelium in the relaxation induced by propofol and thiopental in isolated arteries from man.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:4

    Topics: Aged; Analysis of Variance; Anesthetics, Intravenous; Cyclooxygenase Inhibitors; Endothelium, Vascul

1997
Relaxant effects of propofol on human omental arteries and veins.
    British journal of anaesthesia, 1998, Volume: 80, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Arteries; Culture Techniques; Dose-Respons

1998
The influence of nitrous oxide to supplement fentanyl/low-dose propofol anesthesia on transcranial myogenic motor-evoked potentials during thoracic aortic surgery.
    Journal of cardiothoracic and vascular anesthesia, 1999, Volume: 13, Issue:1

    Topics: Action Potentials; Aged; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; A

1999
The relaxant effect of propofol on guinea pig tracheal muscle is independent of airway epithelial function and beta-adrenoceptor activity.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Carbachol; Epithelium; Female; Guinea Pigs; Histamine; In Vitro T

1999
Inhibitory effects of propofol on acetylcholine-induced, endothelium-dependent relaxation and prostacyclin synthesis in rabbit mesenteric resistance arteries.
    Anesthesiology, 1999, Volume: 91, Issue:4

    Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Endothelium, Vascular; Epoprostenol; In Vitro Tech

1999
Effects of intravenous anesthetics on Ca2+ sensitivity in canine tracheal smooth muscle.
    Anesthesiology, 2000, Volume: 92, Issue:1

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Calcium; Dogs; Female; Halothane; Ketami

2000
Surface vs intramuscular laryngeal electromyography.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:9

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracurium; Electric Stimulation; Electrode

2000
Differential relaxant effect of high concentrations of intravenous anesthetics on endothelin-constricted proximal and distal canine coronary arteries.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:3

    Topics: Anesthetics; Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelins; Female;

1992
Intubation with thiopentone or propofol.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:3

    Topics: Anesthesia; Humans; Intubation, Intratracheal; Muscle Relaxation; Propofol; Thiopental

1992
Preliminary studies on the use of propofol in the domestic pigeon (Columba livia).
    Research in veterinary science, 1990, Volume: 49, Issue:3

    Topics: Anesthesia; Animals; Animals, Domestic; Apnea; Bird Diseases; Columbidae; Female; Heart Rate; Inject

1990
Vascular effects of propofol: smooth muscle relaxation in isolated veins and arteries.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:11

    Topics: Animals; Aorta, Thoracic; Arteries; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation

1989