propofol has been researched along with Meningioma in 8 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this case of 43-old Caucasian male, propofol boluses aborted the trigeminal cardiac reflex (TCR) induced severe bradycardia during dural manipulation." | 3.81 | Severe Bradycardia During Neurosurgical Procedure: Depth of Anesthesia Matters and Leads to a New Surrogate Model of the Trigeminocardiac Reflex: A Case Report. ( Ahuja, N; Chowdhury, T; Schaller, B, 2015) |
| "Propofol was continued using a target-controlled infusion (TCI) system." | 2.72 | Comparison of the time to extubation after use of remifentanil or sufentanil in combination with propofol as anesthesia in adults undergoing nonemergency intracranial surgery: a prospective, randomized, double-blind trial. ( Blanchet, B; Coste, J; Disdet, M; Djian, MC; Gury, C; Joly, LM; Pesce, F; Raggueneau, JL; Roux, FX; Sermet, A; Vazquez, V, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, P | 1 |
| Zhao, L | 1 |
| Wang, T | 1 |
| Mei, W | 1 |
| Li, J | 1 |
| An, Y | 1 |
| Li, L | 1 |
| Li, Z | 1 |
| Yoshino, M | 1 |
| Hara, T | 1 |
| Chowdhury, T | 1 |
| Ahuja, N | 1 |
| Schaller, B | 1 |
| Chakrabarti, D | 1 |
| Surve, RM | 1 |
| Bs, D | 1 |
| Masapu, D | 1 |
| Djian, MC | 1 |
| Blanchet, B | 1 |
| Pesce, F | 1 |
| Sermet, A | 1 |
| Disdet, M | 1 |
| Vazquez, V | 1 |
| Gury, C | 1 |
| Roux, FX | 1 |
| Raggueneau, JL | 1 |
| Coste, J | 1 |
| Joly, LM | 1 |
| Paolo Martorano, P | 1 |
| Falzetti, G | 1 |
| Pelaia, P | 1 |
| Ciritella, P | 1 |
| Scafuro, M | 1 |
| Cafaggi, G | 1 |
| Chiefari, M | 1 |
| De Vivo, P | 1 |
| Todd, MM | 1 |
| Warner, DS | 1 |
| Sokoll, MD | 1 |
| Maktabi, MA | 1 |
| Hindman, BJ | 1 |
| Scamman, FL | 1 |
| Kirschner, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Relationship Between Bispectral Index (BIS) and Spectral Entropy (SpEn) During Desflurane Anaesthesia[NCT01868178] | 50 participants (Actual) | Observational | 2008-09-30 | Completed | |||
| Anaesthesia for Supratentorial Tumor Resection : a Double-blind Comparison of Target Plasma Concentration of Propofol-remifentanil and Sevoflurane-sufentanil[NCT00389883] | Phase 3 | 69 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
| Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351] | Phase 3 | 411 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| The Effect of Furosemide Versus Placebo on Brain Relaxation and Incidence of Significant Intravascular Volume Depletion in Human Subjects Receiving Mannitol[NCT01054404] | 23 participants (Actual) | Interventional | 2010-02-28 | Terminated (stopped due to Concern for volume depletion and electrolyte abnormalities in furosemide arm.) | |||
| Clinical Effectiveness of Hypertonic Sodium Lactate Infusion for Intraoperative Brain Relaxation in Patients Undergoing Scheduled Craniotomy for Supratentorial Brain Tumor Resection: Study Protocol of a Single Center Double-blind Randomized Controlled Pha[NCT04488874] | Phase 3 | 50 participants (Actual) | Interventional | 2020-09-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Rating of brain relaxation will be on a 4-point scale:~0 = brain very relaxed under dura, acceptable~= brain adequately relaxed under dura, acceptable~= brain slightly tense under dura, acceptable~= brain very tense under bulging dura, unacceptable" (NCT01054404)
Timeframe: just prior to dural opening for each subject
| Intervention | units on a scale 0-3 (Mean) |
|---|---|
| Furosemide | 1.5 |
| Placebo | 1.3 |
2 trials available for propofol and Meningioma
6 other studies available for propofol and Meningioma
| Article | Year |
|---|---|
Comparison of Half-Effective Concentration of Propofol in Patients with Parkinson's Disease and Non-Parkinson's Disease.
Topics: Humans; Meningeal Neoplasms; Meningioma; Parkinson Disease; Propofol; Prospective Studies | 2023 |
Light axis adjustment with a sterilised photostimulation device for visually evoked potential monitoring.
Topics: Anesthesia, General; Craniotomy; Electroretinography; Equipment Design; Evoked Potentials, Visual; F | 2018 |
Severe Bradycardia During Neurosurgical Procedure: Depth of Anesthesia Matters and Leads to a New Surrogate Model of the Trigeminocardiac Reflex: A Case Report.
Topics: Adult; Anesthetics, Intravenous; Bradycardia; Craniotomy; Diagnosis, Differential; Humans; Intraoper | 2015 |
Intraoperative aberrant bispectral index values due to facial nerve monitoring.
Topics: Anesthesia, General; Anesthetics, Intravenous; Artifacts; Consciousness Monitors; Craniotomy; Electr | 2017 |
Bispectral index and spectral entropy in neuroanesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Cer | 2006 |
[Total intravenous anesthesia with propofol and fentanyl in surgery of the posterior cranial fossa].
Topics: Adult; Aged; Anesthesia, Intravenous; Cerebrovascular Circulation; Cranial Fossa, Posterior; Embolis | 1993 |