Page last updated: 2024-11-03

propofol and Meningioma

propofol has been researched along with Meningioma in 8 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)

Research Excerpts

ExcerptRelevanceReference
"In this case of 43-old Caucasian male, propofol boluses aborted the trigeminal cardiac reflex (TCR) induced severe bradycardia during dural manipulation."3.81Severe Bradycardia During Neurosurgical Procedure: Depth of Anesthesia Matters and Leads to a New Surrogate Model of the Trigeminocardiac Reflex: A Case Report. ( Ahuja, N; Chowdhury, T; Schaller, B, 2015)
"Propofol was continued using a target-controlled infusion (TCI) system."2.72Comparison of the time to extubation after use of remifentanil or sufentanil in combination with propofol as anesthesia in adults undergoing nonemergency intracranial surgery: a prospective, randomized, double-blind trial. ( Blanchet, B; Coste, J; Disdet, M; Djian, MC; Gury, C; Joly, LM; Pesce, F; Raggueneau, JL; Roux, FX; Sermet, A; Vazquez, V, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Wang, P1
Zhao, L1
Wang, T1
Mei, W1
Li, J1
An, Y1
Li, L1
Li, Z1
Yoshino, M1
Hara, T1
Chowdhury, T1
Ahuja, N1
Schaller, B1
Chakrabarti, D1
Surve, RM1
Bs, D1
Masapu, D1
Djian, MC1
Blanchet, B1
Pesce, F1
Sermet, A1
Disdet, M1
Vazquez, V1
Gury, C1
Roux, FX1
Raggueneau, JL1
Coste, J1
Joly, LM1
Paolo Martorano, P1
Falzetti, G1
Pelaia, P1
Ciritella, P1
Scafuro, M1
Cafaggi, G1
Chiefari, M1
De Vivo, P1
Todd, MM1
Warner, DS1
Sokoll, MD1
Maktabi, MA1
Hindman, BJ1
Scamman, FL1
Kirschner, J1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Relationship Between Bispectral Index (BIS) and Spectral Entropy (SpEn) During Desflurane Anaesthesia[NCT01868178]50 participants (Actual)Observational2008-09-30Completed
Anaesthesia for Supratentorial Tumor Resection : a Double-blind Comparison of Target Plasma Concentration of Propofol-remifentanil and Sevoflurane-sufentanil[NCT00389883]Phase 369 participants (Actual)Interventional2006-11-30Completed
Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351]Phase 3411 participants (Actual)Interventional2007-12-31Completed
The Effect of Furosemide Versus Placebo on Brain Relaxation and Incidence of Significant Intravascular Volume Depletion in Human Subjects Receiving Mannitol[NCT01054404]23 participants (Actual)Interventional2010-02-28Terminated (stopped due to Concern for volume depletion and electrolyte abnormalities in furosemide arm.)
Clinical Effectiveness of Hypertonic Sodium Lactate Infusion for Intraoperative Brain Relaxation in Patients Undergoing Scheduled Craniotomy for Supratentorial Brain Tumor Resection: Study Protocol of a Single Center Double-blind Randomized Controlled Pha[NCT04488874]Phase 350 participants (Actual)Interventional2020-09-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Acceptable vs. Unacceptable Brain Relaxation at Dural Opening

"Rating of brain relaxation will be on a 4-point scale:~0 = brain very relaxed under dura, acceptable~= brain adequately relaxed under dura, acceptable~= brain slightly tense under dura, acceptable~= brain very tense under bulging dura, unacceptable" (NCT01054404)
Timeframe: just prior to dural opening for each subject

Interventionunits on a scale 0-3 (Mean)
Furosemide1.5
Placebo1.3

Trials

2 trials available for propofol and Meningioma

ArticleYear
Comparison of the time to extubation after use of remifentanil or sufentanil in combination with propofol as anesthesia in adults undergoing nonemergency intracranial surgery: a prospective, randomized, double-blind trial.
    Clinical therapeutics, 2006, Volume: 28, Issue:4

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Brain; Costs and Cost Analysis; Cranioto

2006
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma;

1993

Other Studies

6 other studies available for propofol and Meningioma

ArticleYear
Comparison of Half-Effective Concentration of Propofol in Patients with Parkinson's Disease and Non-Parkinson's Disease.
    Clinical interventions in aging, 2023, Volume: 18

    Topics: Humans; Meningeal Neoplasms; Meningioma; Parkinson Disease; Propofol; Prospective Studies

2023
Light axis adjustment with a sterilised photostimulation device for visually evoked potential monitoring.
    British journal of neurosurgery, 2018, Volume: 32, Issue:3

    Topics: Anesthesia, General; Craniotomy; Electroretinography; Equipment Design; Evoked Potentials, Visual; F

2018
Severe Bradycardia During Neurosurgical Procedure: Depth of Anesthesia Matters and Leads to a New Surrogate Model of the Trigeminocardiac Reflex: A Case Report.
    Medicine, 2015, Volume: 94, Issue:49

    Topics: Adult; Anesthetics, Intravenous; Bradycardia; Craniotomy; Diagnosis, Differential; Humans; Intraoper

2015
Intraoperative aberrant bispectral index values due to facial nerve monitoring.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Anesthesia, General; Anesthetics, Intravenous; Artifacts; Consciousness Monitors; Craniotomy; Electr

2017
Bispectral index and spectral entropy in neuroanesthesia.
    Journal of neurosurgical anesthesiology, 2006, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Cer

2006
[Total intravenous anesthesia with propofol and fentanyl in surgery of the posterior cranial fossa].
    Minerva anestesiologica, 1993, Volume: 59, Issue:11

    Topics: Adult; Aged; Anesthesia, Intravenous; Cerebrovascular Circulation; Cranial Fossa, Posterior; Embolis

1993