Page last updated: 2024-11-03

propofol and Melanoma

propofol has been researched along with Melanoma in 3 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"Propofol is an intravenous anesthetic widely used in clinical surgeries, such as tumor resection."5.51Propofol suppresses proliferation, invasion, and migration of human melanoma cells via regulating microRNA-137 and fibroblast growth factor 9. ( Guo, Q; Li, R; Ma, M; Wang, X; Yu, H; Zhou, Z, 2019)
"To test whether prophylactic neural blockade of noziceptive afferents or antiemetics diminutes postoperative nausea and vomiting (PONV) we studied in a randomised, prospective, and ouble-blind fashion 102 patients receiving implantation of an episcleral radioactive applicator for treatment of ocular malignant melanoma during remifentanil-propofol-anaesthesia."5.10[Blocking nociceptive afferents by retrobulbar bupivacaine does not decrease nausea and vomiting after propofol-remifentanil anaesthesia]. ( Apfel, CC; Armbruster, W; Bornfeld, N; Müller, D; Peters, J; Unkel, W, 2003)
"Propofol is an intravenous anesthetic widely used in clinical surgeries, such as tumor resection."1.51Propofol suppresses proliferation, invasion, and migration of human melanoma cells via regulating microRNA-137 and fibroblast growth factor 9. ( Guo, Q; Li, R; Ma, M; Wang, X; Yu, H; Zhou, Z, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yu, H1
Ma, M1
Wang, X1
Zhou, Z1
Li, R1
Guo, Q1
Yosry, M1
Othman, IS1
Müller, D1
Armbruster, W1
Unkel, W1
Apfel, CC1
Bornfeld, N1
Peters, J1

Trials

2 trials available for propofol and Melanoma

ArticleYear
Controlled hypotension in adults undergoing choroidal melanoma resection: comparison between the efficacy of nitroprusside and magnesium sulphate.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:11

    Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Choroid Neoplasms; Female; Heart Rate; Hemodynamics

2008
[Blocking nociceptive afferents by retrobulbar bupivacaine does not decrease nausea and vomiting after propofol-remifentanil anaesthesia].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2003, Volume: 38, Issue:11

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Double-Bli

2003

Other Studies

1 other study available for propofol and Melanoma

ArticleYear
Propofol suppresses proliferation, invasion, and migration of human melanoma cells via regulating microRNA-137 and fibroblast growth factor 9.
    Journal of cellular physiology, 2019, Volume: 234, Issue:12

    Topics: Anesthetics, Intravenous; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation

2019