propofol has been researched along with Lung Neoplasms in 54 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the study was to investigate the effects of propofol and sevoflurane on malignant biological behavior and cisplatin resistance of Xuanwei lung adenocarcinoma." | 8.12 | Propofol and Sevoflurane Alleviate Malignant Biological Behavior and Cisplatin Resistance of Xuanwei Lung Adenocarcinoma by Modulating the Wnt/β-catenin Pathway and PI3K/AKT Pathway. ( Li, S; Liu, G; Lv, Z; Quan, Y; Wang, Y; Wang, Z, 2022) |
| "Propofol may help to protect against ischaemic acute kidney injury (AKI); however, research on this topic is sparse." | 7.91 | Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis. ( Han, S; Jheon, S; Ji, E; Kim, J; Kim, K; Oh, TK, 2019) |
| "Propofol is a known anesthetic agent, widely used for short-term anesthesia and for longer-term sedation." | 5.38 | Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells. ( Chiou, SM; Chung, JG; Hsia, TC; Lu, CC; Wu, KC; Wu, RS; Yang, JS; Yang, ST, 2012) |
| "Limb RIPC attenuates acute lung injury via improving intraoperative pulmonary oxygenation in patients without severe pulmonary disease after lung resection under propofol-remifentanil anesthesia." | 5.19 | Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol-remifentanil anesthesia: a randomized controlled study. ( Huang, WQ; Li, C; Li, YS; Liu, KX; Wu, Y; Xu, M, 2014) |
| "The objective of the study was to investigate the effects of propofol and sevoflurane on malignant biological behavior and cisplatin resistance of Xuanwei lung adenocarcinoma." | 4.12 | Propofol and Sevoflurane Alleviate Malignant Biological Behavior and Cisplatin Resistance of Xuanwei Lung Adenocarcinoma by Modulating the Wnt/β-catenin Pathway and PI3K/AKT Pathway. ( Li, S; Liu, G; Lv, Z; Quan, Y; Wang, Y; Wang, Z, 2022) |
| " Here we show that surgical dissection of primary tumors in mice under anesthesia with sevoflurane leads to significantly more lung metastasis than with propofol in both syngeneic murine 4T1 and xenograft human MDA-MB-231 breast cancer models." | 3.96 | Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models. ( Huang, Y; Li, R; Lin, J, 2020) |
| "Propofol may help to protect against ischaemic acute kidney injury (AKI); however, research on this topic is sparse." | 3.91 | Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis. ( Han, S; Jheon, S; Ji, E; Kim, J; Kim, K; Oh, TK, 2019) |
| "High-dose propofol infusion for sedation of patients in the intensive care unit can result in rhabdomyolysis, acute renal failure, metabolic acidosis, hyperkalemia, ventricular arrhythmia, hyperthermia, and death." | 3.73 | A lethal complication of propofol. ( Chavez, VM; Haake, RJ; Hayat, SA; Suen, HC, 2006) |
| "Propofol has a more significant adverse effect on postoperative cognitive function in elderly patients with lung cancer than sevoflurane." | 2.61 | A systematic review: comparative analysis of the effects of propofol and sevoflurane on postoperative cognitive function in elderly patients with lung cancer. ( Ai, B; Kong, X; Lee, WT; Sun, H; Sun, L; Yan, T; Zhang, G; Zhang, H; Zheng, H, 2019) |
| "Propofol functions as a tumor-inhibitor drug by regulating microRNAs (miRNAs)." | 1.91 | Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis. ( Han, B; Liang, L; Liu, Y; Zhang, Q, 2023) |
| "Propofol-based TIVA was associated with better RFS and OS than inhalation anesthesia in patients with stage I/II NSCLC who underwent curative resection." | 1.91 | Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study. ( Chon, JY; Hong, JH; Hong, SH; Hwang, W; Kim, S; Kwon, H; Lee, SW; Moon, MH; Seo, KH, 2023) |
| "Propofol-based TIVA was associated with a better prognosis in comparison to INHA in patients with surgically resected pathological stage I NSCLC." | 1.62 | Prognostic significance of propofol-based intravenous anesthesia in early-stage lung cancer surgery. ( Endoh, M; Hayasaka, K; Miyata, S; Okada, Y; Shiono, S; Takaoka, S, 2021) |
| "Propofol is a commonly used anesthetic for cancer surgery." | 1.62 | Propofol suppresses lung cancer tumorigenesis by modulating the circ-ERBB2/miR-7-5p/FOXM1 axis. ( Ding, C; Gao, J; Han, Z; Hei, F; Li, J; Wu, G; Zhou, J, 2021) |
| "Propofol- or vehicle-treated tumor cells are also injected to the mice." | 1.62 | Anesthetic Propofol Promotes Tumor Metastasis in Lungs via GABA ( Cheng, C; Lanuti, M; Liu, Q; Liu, R; Shen, Y; Sheng, Z; Wang, P; Xie, Z; Zheng, H, 2021) |
| "Propofol is an anesthetic drug frequently used during tumor resection." | 1.56 | Propofol suppresses the progression of non‑small cell lung cancer via downregulation of the miR‑21‑5p/MAPK10 axis. ( Li, X; Wu, X; Xu, G, 2020) |
| "Propofol is a common sedative-hypnotic drug traditionally used for inducing and maintaining general anesthesia." | 1.56 | Propofol Affects Non-Small-Cell Lung Cancer Cell Biology By Regulating the miR-21/PTEN/AKT Pathway In Vitro and In Vivo. ( Dong, L; Ge, X; Li, Q; Li, R; Liu, D; Wang, G; Zhao, S; Zheng, X; Zhu, X, 2020) |
| " The dosage of opioids during and 24 h after operation, the pain score at 2, 8, 24, 48, and 72 h after operation, and the concentrations of serum VEGF and TGF-β before and 24 h after operation were observed in the two groups." | 1.51 | Effect of thoracic paraspinal block-propofol intravenous general anesthesia on VEGF and TGF-β in patients receiving radical resection of lung cancer. ( Sen, Y; Xiyang, H; Yu, H, 2019) |
| "Propofol has been widely used in lung cancer resections." | 1.48 | Propofol Inhibits Lung Cancer A549 Cell Growth and Epithelial-Mesenchymal Transition Process by Upregulation of MicroRNA-1284. ( Liu, N; Liu, WZ, 2018) |
| "Propofol treatment inhibited viability and induced apoptosis of A549 cells in a dose-dependent manner in vitro." | 1.48 | Propofol induces apoptosis of non-small cell lung cancer cells via ERK1/2-dependent upregulation of PUMA. ( Luan, Q; Qu, JH; Ren, YD; Xing, SG; Zhang, KJ, 2018) |
| "Propofol is a frequently used intravenous anesthetic agent." | 1.46 | Propofol inhibits lung cancer cell viability and induces cell apoptosis by upregulating microRNA-486 expression. ( Jiang, L; Liang, Y; Yang, N; Yang, P; Yang, T, 2017) |
| "Three weeks later, pulmonary metastasis tumor foci and metastatic inhibitory rate were observed and the expression of E-cadherin and β-catenin in the metastatic tumor tissue were detected by immunohistochemistry." | 1.42 | [Effects of propofol on pulmonary metastasis of intravenously injected MADB106 tumor cells and expression of E-cadherin and β-catenin in rats]. ( Chen, Y; Guo, P; Lin, C; Wang, W; Zhang, Y, 2015) |
| "Pulmonary metastasis of the tumor cells was observed and the expression of MTA1 and Wnt1 in the metastatic tumor detected by immunohistochemistry 3 weeks later." | 1.40 | [Effects of propofol on pulmonary metastasis of intravenous injected tumor cells and expressions of MTA1 and Wnt1 in rats]. ( Chen, Y; Lin, C; Wang, W; Zhang, Y, 2014) |
| "Propofol is a known anesthetic agent, widely used for short-term anesthesia and for longer-term sedation." | 1.38 | Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells. ( Chiou, SM; Chung, JG; Hsia, TC; Lu, CC; Wu, KC; Wu, RS; Yang, JS; Yang, ST, 2012) |
| "Three weeks later, the lung metastases were counted." | 1.35 | [Effects of neuraxial block and general anesthesia on tumor metastasis in rats]. ( Lai, RC; Li, YP; Lu, YL; Shen, ZW; Wang, XD; Zheng, W, 2008) |
| "Ketamine was most deleterious, and its effects were prevented by peripheral blockade of beta-adrenoceptors combined with low levels of immunostimulation." | 1.32 | Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures. ( Bar-Yosef, S; Ben-Eliyahu, S; Melamed, R; Shakhar, G; Shakhar, K, 2003) |
| " A cumulative dose-response curve for vecuronium was constructed, and pupillary changes in response to various noxious stimuli were evaluated with concomitant recording of the Spectral-Edge-Frequency 90% (SEF90; the frequency below which 90 percent of the EEG power is located)." | 1.30 | Vecuronium dose requirement and pupillary response in a patient with olivopontocerebellar atrophy (OPCA). ( Fukura, H; Goto, F; Kuroda, M; Morita, T; Saruki, N; Yoshikawa, D, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.85) | 18.7374 |
| 1990's | 2 (3.70) | 18.2507 |
| 2000's | 7 (12.96) | 29.6817 |
| 2010's | 25 (46.30) | 24.3611 |
| 2020's | 19 (35.19) | 2.80 |
| Authors | Studies |
|---|---|
| Quan, Y | 1 |
| Li, S | 1 |
| Wang, Y | 3 |
| Liu, G | 1 |
| Lv, Z | 1 |
| Wang, Z | 1 |
| Chen, L | 1 |
| Wu, G | 2 |
| Li, Y | 1 |
| Cai, Q | 1 |
| Ling, Q | 1 |
| Wu, S | 1 |
| Liao, X | 1 |
| Liu, C | 1 |
| Chen, Y | 3 |
| Han, B | 3 |
| Liu, Y | 5 |
| Zhang, Q | 3 |
| Liang, L | 3 |
| Cui, C | 3 |
| Zhang, D | 3 |
| Sun, K | 3 |
| Zhu, Y | 3 |
| Xu, J | 3 |
| Kang, Y | 3 |
| Zhang, G | 4 |
| Cai, Y | 3 |
| Mao, S | 3 |
| Long, R | 3 |
| Ma, J | 3 |
| Dong, S | 3 |
| Sun, Y | 3 |
| Seo, KH | 1 |
| Hong, JH | 1 |
| Moon, MH | 1 |
| Hwang, W | 1 |
| Lee, SW | 1 |
| Chon, JY | 1 |
| Kwon, H | 1 |
| Hong, SH | 1 |
| Kim, S | 1 |
| Wang, S | 1 |
| Li, M | 1 |
| Cai, S | 1 |
| Zhang, W | 1 |
| Zhang, X | 2 |
| Liu, D | 2 |
| Wang, P | 2 |
| Liu, N | 2 |
| Tan, J | 1 |
| Wang, L | 2 |
| Song, X | 1 |
| Zhang, Y | 3 |
| Song, Z | 1 |
| Duan, M | 1 |
| Sen, Y | 1 |
| Xiyang, H | 1 |
| Yu, H | 1 |
| Sun, H | 2 |
| Ai, B | 1 |
| Zhang, H | 1 |
| Kong, X | 1 |
| Lee, WT | 1 |
| Zheng, H | 2 |
| Yan, T | 1 |
| Sun, L | 1 |
| Li, R | 2 |
| Huang, Y | 2 |
| Lin, J | 1 |
| Lei, L | 1 |
| Wu, X | 1 |
| Li, X | 2 |
| Xu, G | 1 |
| Tian, D | 1 |
| Tian, M | 1 |
| Ma, ZM | 1 |
| Zhang, LL | 1 |
| Cui, YF | 1 |
| Li, JL | 1 |
| Zhao, H | 1 |
| Wei, H | 1 |
| He, J | 1 |
| Wang, D | 1 |
| Li, W | 1 |
| Ai, Y | 1 |
| Yang, J | 1 |
| Zheng, X | 1 |
| Dong, L | 1 |
| Zhao, S | 1 |
| Li, Q | 1 |
| Zhu, X | 1 |
| Ge, X | 1 |
| Wang, G | 1 |
| Hayasaka, K | 1 |
| Shiono, S | 1 |
| Miyata, S | 1 |
| Takaoka, S | 1 |
| Endoh, M | 1 |
| Okada, Y | 1 |
| Gao, J | 1 |
| Ding, C | 1 |
| Zhou, J | 1 |
| Han, Z | 1 |
| Li, J | 2 |
| Hei, F | 1 |
| Hu, C | 1 |
| Iwasaki, M | 1 |
| Liu, Z | 1 |
| Wang, B | 1 |
| Lin, H | 1 |
| Li, JV | 1 |
| Lian, Q | 1 |
| Ma, D | 1 |
| Liu, Q | 1 |
| Sheng, Z | 1 |
| Cheng, C | 1 |
| Lanuti, M | 1 |
| Liu, R | 1 |
| Shen, Y | 1 |
| Xie, Z | 1 |
| Yang, N | 2 |
| Liang, Y | 2 |
| Yang, P | 2 |
| Ji, F | 1 |
| Tian, HT | 1 |
| Duan, XH | 1 |
| Yang, YF | 1 |
| Bai, QL | 1 |
| Liu, WZ | 1 |
| Xing, SG | 1 |
| Zhang, KJ | 1 |
| Qu, JH | 1 |
| Ren, YD | 1 |
| Luan, Q | 1 |
| Conte, SC | 1 |
| Spagnol, G | 1 |
| Confalonieri, M | 1 |
| Brizi, B | 1 |
| Gao, D | 1 |
| Qin, Y | 1 |
| Ni, J | 1 |
| Kang, L | 1 |
| Zhong, Z | 1 |
| Yin, S | 1 |
| Oh, TK | 1 |
| Kim, J | 1 |
| Han, S | 1 |
| Kim, K | 1 |
| Jheon, S | 1 |
| Ji, E | 1 |
| Cui, WY | 1 |
| Zhu, YQ | 1 |
| Song, T | 1 |
| Wang, QS | 1 |
| Li, C | 1 |
| Xu, M | 1 |
| Wu, Y | 1 |
| Li, YS | 1 |
| Huang, WQ | 1 |
| Liu, KX | 1 |
| Lin, C | 2 |
| Wang, W | 3 |
| Potočnik, I | 1 |
| Novak Janković, V | 1 |
| Šostarič, M | 1 |
| Jerin, A | 1 |
| Štupnik, T | 1 |
| Skitek, M | 1 |
| Markovič-Božič, J | 1 |
| Klokočovnik, T | 1 |
| Guo, P | 1 |
| Chrissian, AA | 1 |
| Bedi, H | 1 |
| Imajo, Y | 1 |
| Komasawa, N | 1 |
| Kusaka, Y | 1 |
| Kido, H | 1 |
| Minami, T | 1 |
| Ye, HJ | 1 |
| Bai, JJ | 1 |
| Guo, PP | 1 |
| Lin, CS | 1 |
| Yang, T | 1 |
| Jiang, L | 1 |
| Zheng, W | 1 |
| Li, YP | 1 |
| Lai, RC | 1 |
| Lu, YL | 1 |
| Shen, ZW | 1 |
| Wang, XD | 1 |
| Shibuya, K | 1 |
| Ishiyama, T | 1 |
| Ichikawa, M | 1 |
| Oguchi, T | 1 |
| Matsukawa, T | 1 |
| Ren, XF | 1 |
| Li, WZ | 1 |
| Meng, FY | 1 |
| Lin, CF | 1 |
| Yamamoto, T | 1 |
| Honma, T | 1 |
| Ikoma, M | 1 |
| Baba, H | 1 |
| Kohno, T | 1 |
| Hu, XL | 1 |
| Tang, HH | 1 |
| Zhou, ZG | 1 |
| Yin, F | 1 |
| Liu, WJ | 1 |
| Song, JG | 1 |
| Shin, JW | 1 |
| Lee, EH | 1 |
| Choi, DK | 1 |
| Bang, JY | 1 |
| Chin, JH | 1 |
| Choi, IC | 1 |
| Wu, KC | 1 |
| Yang, ST | 1 |
| Hsia, TC | 1 |
| Yang, JS | 1 |
| Chiou, SM | 1 |
| Lu, CC | 1 |
| Wu, RS | 1 |
| Chung, JG | 1 |
| Mammoto, T | 1 |
| Mukai, M | 1 |
| Mammoto, A | 1 |
| Yamanaka, Y | 1 |
| Hayashi, Y | 1 |
| Mashimo, T | 1 |
| Kishi, Y | 1 |
| Nakamura, H | 1 |
| Melamed, R | 1 |
| Bar-Yosef, S | 1 |
| Shakhar, G | 1 |
| Shakhar, K | 1 |
| Ben-Eliyahu, S | 1 |
| Suen, HC | 1 |
| Haake, RJ | 1 |
| Chavez, VM | 1 |
| Hayat, SA | 1 |
| Ivani, G | 1 |
| Mossetti, V | 1 |
| Andreacchio, A | 1 |
| Kuroda, M | 1 |
| Fukura, H | 1 |
| Saruki, N | 1 |
| Yoshikawa, D | 1 |
| Morita, T | 1 |
| Goto, F | 1 |
| Fujiwara, C | 1 |
| Hirose, Y | 1 |
| Gamo, M | 1 |
| Harigae, M | 1 |
| Matsuo, K | 1 |
| Leonard, IE | 1 |
| Myles, PS | 1 |
| Dewachter, P | 1 |
| Boileau, S | 1 |
| Laxenaire, MC | 1 |
| Domenegati, E | 1 |
| Ciccone, R | 1 |
| Reali, F | 1 |
| Reposi, C | 1 |
| De Amici, D | 1 |
| Rissotti, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metabolomic Profiling of Erector Spinae Plane Block for Breast Cancer Surgery[NCT04689945] | 91 participants (Actual) | Observational | 2021-02-01 | Completed | |||
| Postoperative Effects of Propofol or Sevoflurane Anesthesia in Egyptian Patients[NCT05289349] | 44 participants (Actual) | Interventional | 2021-12-01 | Completed | |||
| Correlation Between Blood Pressure, Heart Rate and Plasma Corticotropin, Cortisol Under Surgical Skin Incision[NCT03892538] | 134 participants (Actual) | Observational | 2018-10-01 | Completed | |||
| Phase 1 Study of Antiinflammatory Effect of Sevoflurane in Open Lung Surgery With One-Lung Ventilation[NCT02188407] | Phase 1 | 40 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Active, not recruiting | |||
| A Prospective, Randomized, Controlled Trial to Compare the Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serumserum Biomarkers and on PBMCs in Patients Undergoing Breast Cancer Resection Surgery[NCT03005860] | 0 participants (Actual) | Interventional | 2017-01-01 | Withdrawn (stopped due to Funding could not be arranged, so the study was prematurely terminated) | |||
| A Randomized, Open-label Study to Compare Propofol Anesthesia With Sevoflurane Anesthesia in Terms of Overall Survival in Patients With Surgical Intervention for Either Breast-, Colon- or Rectal Cancer[NCT01975064] | Phase 4 | 5,774 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Impact of Epidural Anesthesia-analgesia on Long-term Outcome in Elderly Patients After Surgery: 5-year Follow-up of a Multicenter Randomized Controlled Trial[NCT03012945] | 1,802 participants (Actual) | Interventional | 2014-11-01 | Completed | |||
| Impact of Epidural Anesthesia-analgesia on Long-term Outcomes in Elderly Patients After Surgery: 5-year Follow-up of a Multicenter Randomized Controlled Trial[NCT03335826] | 1,802 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propofol and Lung Neoplasms
| Article | Year |
|---|---|
A systematic review: comparative analysis of the effects of propofol and sevoflurane on postoperative cognitive function in elderly patients with lung cancer.
Topics: Age Factors; Aged, 80 and over; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Cogni | 2019 |
6 trials available for propofol and Lung Neoplasms
| Article | Year |
|---|---|
Transcriptome analysis reveals the differential inflammatory effects between propofol and sevoflurane during lung cancer resection: a randomized pilot study.
Topics: Anesthetics; Chemokines; Gene Expression Profiling; Humans; Lung Neoplasms; Methyl Ethers; Pilot Pro | 2023 |
Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol-remifentanil anesthesia: a randomized controlled study.
Topics: Acute Lung Injury; Aged; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intravenous; Ca | 2014 |
Antiinflammatory effect of sevoflurane in open lung surgery with one-lung ventilation.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cytokines; Female; Humans; Inflammat | 2014 |
Differential effects of propofol and isoflurane on the activation of T-helper cells in lung cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell Lung; Cell | 2010 |
Differential effects of propofol and isoflurane on the activation of T-helper cells in lung cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell Lung; Cell | 2010 |
Differential effects of propofol and isoflurane on the activation of T-helper cells in lung cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell Lung; Cell | 2010 |
Differential effects of propofol and isoflurane on the activation of T-helper cells in lung cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell Lung; Cell | 2010 |
[The effect of sevoflurane inhalation anesthesia only and propofol total intravenous anesthesia on perioperative cytokine balance in lung cancer patients].
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Cytokines; Female; Humans; Interleukin | 2011 |
Incidence of post-thoracotomy pain: a comparison between total intravenous anaesthesia and inhalation anaesthesia.
Topics: Acute Pain; Adolescent; Adult; Aged; Analgesics; Anesthesia, Inhalation; Anesthesia, Intravenous; An | 2012 |
47 other studies available for propofol and Lung Neoplasms
| Article | Year |
|---|---|
Propofol and Sevoflurane Alleviate Malignant Biological Behavior and Cisplatin Resistance of Xuanwei Lung Adenocarcinoma by Modulating the Wnt/β-catenin Pathway and PI3K/AKT Pathway.
Topics: Adenocarcinoma of Lung; Apoptosis; beta Catenin; Cell Line, Tumor; Cell Proliferation; China; Cispla | 2022 |
Anesthetic propofol suppresses growth and metastasis of lung adenocarcinoma in vitro through downregulating circ-MEMO1-miR-485-3p-NEK4 ceRNA axis.
Topics: Adenocarcinoma of Lung; Anesthetics; Cadherins; Cell Line, Tumor; Cell Proliferation; Humans; Intrac | 2022 |
Anesthetic propofol enhances cisplatin-sensitivity of non-small cell lung cancer cells through N6-methyladenosine-dependently regulating the miR-486-5p/RAP1-NF-κB axis.
Topics: Adenosine; Anesthetics; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cispla | 2022 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor.
Topics: Animals; Lung Neoplasms; Mice; Propofol; Receptors, GABA; Receptors, GABA-A; T-Lymphocytes, Regulato | 2022 |
Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell | 2023 |
Propofol mediates non-small cell lung cancer growth in part by regulating circ_0003028-related mechanisms.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Mice | 2023 |
Optimization of a tri-drug treatment against lung cancer using orthogonal design in preclinical studies.
Topics: Anesthetics, Combined; Humans; Lung Neoplasms; Propofol; Rocuronium; Sufentanil | 2023 |
Effect of thoracic paraspinal block-propofol intravenous general anesthesia on VEGF and TGF-β in patients receiving radical resection of lung cancer.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anest | 2019 |
Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models.
Topics: Anesthetics, General; Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; H | 2020 |
Propofol Improves Sensitivity of Lung Cancer Cells to Cisplatin and Its Mechanism.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cisplatin; Dose-Response Relations | 2020 |
Propofol suppresses the progression of non‑small cell lung cancer via downregulation of the miR‑21‑5p/MAPK10 axis.
Topics: 3' Untranslated Regions; A549 Cells; Adult; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell P | 2020 |
Anesthetic propofol epigenetically regulates breast cancer trastuzumab resistance through IL-6/miR-149-5p axis.
Topics: Anesthetics; Animals; Antagomirs; Antineoplastic Agents, Immunological; Breast Neoplasms; Cell Line, | 2020 |
Propofol disrupts cell carcinogenesis and aerobic glycolysis by regulating circTADA2A/miR-455-3p/FOXM1 axis in lung cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Female; Forkhead Box | 2020 |
Propofol Affects Non-Small-Cell Lung Cancer Cell Biology By Regulating the miR-21/PTEN/AKT Pathway In Vitro and In Vivo.
Topics: A549 Cells; Anesthetics, Intravenous; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Smal | 2020 |
Prognostic significance of propofol-based intravenous anesthesia in early-stage lung cancer surgery.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Carcinoma, Non-Small-Cell Lung; Female; Human | 2021 |
Propofol suppresses lung cancer tumorigenesis by modulating the circ-ERBB2/miR-7-5p/FOXM1 axis.
Topics: Anesthetics, Intravenous; Animals; Carcinogenesis; Cell Culture Techniques; Cell Proliferation; Huma | 2021 |
Lung but not brain cancer cell malignancy inhibited by commonly used anesthetic propofol during surgery: Implication of reducing cancer recurrence risk.
Topics: A549 Cells; Anesthetics, Intravenous; Antineoplastic Agents; Brain Neoplasms; Cell Movement; Cell Pr | 2021 |
Anesthetic Propofol Promotes Tumor Metastasis in Lungs via GABA
Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Female; Lung Neoplasms; Mice; Mice, Inbre | 2021 |
Propofol suppresses LPS-induced nuclear accumulation of HIF-1α and tumor aggressiveness in non-small cell lung cancer.
Topics: A549 Cells; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; | 2017 |
Effects of propofol or sevoflurane anesthesia on the perioperative inflammatory response, pulmonary function and cognitive function in patients receiving lung cancer resection.
Topics: Aged; Aged, 80 and over; Anesthetics; Bradycardia; Cognition; Female; Humans; Interleukin-10; Interl | 2017 |
Propofol Inhibits Lung Cancer A549 Cell Growth and Epithelial-Mesenchymal Transition Process by Upregulation of MicroRNA-1284.
Topics: A549 Cells; Cell Movement; Cell Proliferation; Cell Survival; Epithelial-Mesenchymal Transition; For | 2018 |
Propofol induces apoptosis of non-small cell lung cancer cells via ERK1/2-dependent upregulation of PUMA.
Topics: A549 Cells; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Humans; Lung N | 2018 |
Deep sedation versus minimal sedation during endobronchial ultrasound transbronchial needle aspiration.
Topics: Adenocarcinoma; Adjuvants, Anesthesia; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Ant | 2018 |
Propofol suppresses growth, migration and invasion of A549 cells by down-regulation of miR-372.
Topics: A549 Cells; Cell Movement; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplast | 2018 |
Sevoflurane Effect on Cognitive Function and the Expression of Oxidative Stress Response Proteins in Elderly Patients undergoing Radical Surgery for Lung Cancer.
Topics: Administration, Inhalation; Aged; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Ch | 2019 |
Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis.
Topics: Acute Kidney Injury; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; C | 2019 |
Propofol induces endoplasmic reticulum (ER) stress and apoptosis in lung cancer cell H460.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Stress; Humans; Lung Neoplasm | 2014 |
[Effects of propofol on pulmonary metastasis of intravenous injected tumor cells and expressions of MTA1 and Wnt1 in rats].
Topics: Animals; Immunohistochemistry; Injections, Intravenous; Lung Neoplasms; Male; Neoplasm Metastasis; P | 2014 |
[Effects of propofol on pulmonary metastasis of intravenously injected MADB106 tumor cells and expression of E-cadherin and β-catenin in rats].
Topics: Animals; beta Catenin; Cadherins; Dose-Response Relationship, Drug; Down-Regulation; Immunohistochem | 2015 |
Bronchoscopist-directed Continuous Propofol Infusion for Targeting Moderate Sedation During Endobronchial Ultrasound Bronchoscopy: A Practical and Effective Protocol.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Bronchoscopy; Cohort Studies; Conscious Sedatio | 2015 |
[Anesthetic Management for Lobectomy in a Patient with Pulmonary Arterial Hypertension].
Topics: Aged; Anesthesia; Dexmedetomidine; Female; Fentanyl; Humans; Hypertension, Pulmonary; Lung Neoplasms | 2016 |
[Propofol suppresses invasion of human lung cancer A549 cells by down-regulating aquaporin-3 and matrix metalloproteinase-9].
Topics: A549 Cells; Aquaporin 3; Cell Movement; Down-Regulation; Humans; Lung Neoplasms; Matrix Metalloprote | 2016 |
Propofol inhibits lung cancer cell viability and induces cell apoptosis by upregulating microRNA-486 expression.
Topics: Apoptosis; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; | 2017 |
[Effects of neuraxial block and general anesthesia on tumor metastasis in rats].
Topics: Anesthesia, Epidural; Anesthesia, General; Animals; Breast Neoplasms; Female; Immunologic Surveillan | 2008 |
[Mobitz type II block during one-lung ventilation].
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Atrioventricular Block; Fentanyl; Humans; Intraoper | 2010 |
[Case of profound bradycardia and cardiac arrest during left upper lobectomy and lymph node dissection].
Topics: Anesthesia, Epidural; Anesthesia, General; Bradycardia; Cardiac Pacing, Artificial; Electrocoagulati | 2010 |
Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; | 2012 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
Suppression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol: mediating mechanisms and prophylactic measures.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Anesthetics; Anesthetics, Dissociative; Anesthe | 2003 |
A lethal complication of propofol.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Creatine Kinase; Dose-Response Relat | 2006 |
Ultrasound-guided peripheral catheter placement for upper limb amputation in a 12-year-old boy: possible phantom limb pain prevention?
Topics: Amputation, Surgical; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bone Ne | 2008 |
Vecuronium dose requirement and pupillary response in a patient with olivopontocerebellar atrophy (OPCA).
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Autonomic Nervous System; Dose-Response Rel | 1998 |
[Anesthetic management for placement of tracheobronchial stents in patients with airway stenosis].
Topics: Adult; Aged; Anesthesia, Intravenous; Esophageal Neoplasms; Female; Fentanyl; Humans; Lung Neoplasms | 2000 |
Target-controlled intravenous anaesthesia with bispectral index monitoring for thoracotomy in a patient with severely impaired left ventricular function.
Topics: Aged; Analgesia, Epidural; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intrave | 2000 |
[The reduction of anesthetic risk by high frequency jet ventilation during endobronchial cryotherapy].
Topics: Adult; Aged; Anesthesia, Intravenous; Cryosurgery; Fentanyl; High-Frequency Jet Ventilation; Humans; | 1991 |
[Anesthesiologic management for lower pulmonary lobectomy intervention in patients with heart transplant. A clinical case].
Topics: Adenocarcinoma; Anesthesia, General; Fentanyl; Heart Transplantation; Humans; Lung Neoplasms; Male; | 1989 |