propofol has been researched along with Lung Injury, Ventilator-Induced in 5 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol treatment may alleviate the VALI in rats by reducing the inflammatory response and inhibiting the activation of p38 MAPK signaling pathway." | 1.62 | Effects of propofol on inflammatory response and activation of p38 MAPK signaling pathway in rats with ventilator-induced lung injury. ( Deng, J; Liao, C; Xiang, T; Xiong, M, 2021) |
| "Propofol treatment improved VILI, alleviated pulmonary inflammation induced by mechanical ventilation." | 1.56 | Propofol alleviates ventilator-induced lung injury through regulating the Nrf2/NLRP3 signaling pathway. ( Chen, G; Li, W; Ruan, H; Wang, J; Wang, Z; Xia, B; Zhang, M, 2020) |
| " Clinical data imply a correlation between cumulative propofol dosage and diaphragm dysfunction, whereas laboratory investigations have revealed that propofol has some antioxidant properties." | 1.40 | Sedation using propofol induces similar diaphragm dysfunction and atrophy during spontaneous breathing and mechanical ventilation in rats. ( Bergs, I; Bleilevens, C; Bruells, CS; Cielen, N; Gayan-Ramirez, G; Maes, K; Rossaint, R; Thomas, D; Weis, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, J | 1 |
| Xiong, M | 1 |
| Liao, C | 1 |
| Xiang, T | 1 |
| Ruan, H | 1 |
| Li, W | 1 |
| Wang, J | 1 |
| Chen, G | 1 |
| Xia, B | 1 |
| Wang, Z | 1 |
| Zhang, M | 1 |
| Payen, JF | 1 |
| Chanques, G | 1 |
| Futier, E | 1 |
| Velly, L | 1 |
| Jaber, S | 1 |
| Constantin, JM | 1 |
| Feng, Z | 1 |
| Wang, JW | 1 |
| Wang, Y | 1 |
| Dong, WW | 1 |
| Xu, ZF | 1 |
| Bruells, CS | 1 |
| Maes, K | 1 |
| Rossaint, R | 1 |
| Thomas, D | 1 |
| Cielen, N | 1 |
| Bergs, I | 1 |
| Bleilevens, C | 1 |
| Weis, J | 1 |
| Gayan-Ramirez, G | 1 |
1 review available for propofol and Lung Injury, Ventilator-Induced
| Article | Year |
|---|---|
Sedation for critically ill patients with COVID-19: Which specificities? One size does not fit all.
Topics: Analgesics, Opioid; Betacoronavirus; Coronavirus Infections; COVID-19; Critical Illness; Deep Sedati | 2020 |
4 other studies available for propofol and Lung Injury, Ventilator-Induced
| Article | Year |
|---|---|
Effects of propofol on inflammatory response and activation of p38 MAPK signaling pathway in rats with ventilator-induced lung injury.
Topics: Animals; Lung; p38 Mitogen-Activated Protein Kinases; Propofol; Rats; Rats, Sprague-Dawley; Signal T | 2021 |
Propofol alleviates ventilator-induced lung injury through regulating the Nrf2/NLRP3 signaling pathway.
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Lung; Mice; Mitochondria; NF-E2-Related Facto | 2020 |
Propofol Protects Lung Endothelial Barrier Function by Suppression of High-Mobility Group Box 1 (HMGB1) Release and Mitochondrial Oxidative Damage Catalyzed by HMGB1.
Topics: Acute Lung Injury; Animals; Catalysis; Disease Models, Animal; Endothelial Cells; Endothelium, Vascu | 2019 |
Sedation using propofol induces similar diaphragm dysfunction and atrophy during spontaneous breathing and mechanical ventilation in rats.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Diaphragm; Disease Models, Animal; Male; Mu | 2014 |