propofol has been researched along with Long QT Syndrome in 20 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of congenital long QT syndrome which developed torsade de pointes during sevoflurane anesthesia for implantation of an internal cardioverter-defibrillator." | 7.73 | Torsade de pointes during sevoflurane anesthesia in a child with congenital long QT syndrome. ( Davy, JM; Frapier, JM; Massad, I; Raczka, F; Saussine, M, 2006) |
| "This simulation study was designed to predict the torsadogenicity of sevoflurane and propofol in healthy control, as well as type 1 and type 2 long QT syndrome (LQT1 and LQT2, respectively), using the O'Hara-Rudy dynamic model." | 4.31 | Prediction of anesthetic torsadogenicity using a human ventricular cell model. ( Fukushima, Y; Kojima, A; Matsuura, H, 2023) |
| "We present a case of congenital long QT syndrome which developed torsade de pointes during sevoflurane anesthesia for implantation of an internal cardioverter-defibrillator." | 3.73 | Torsade de pointes during sevoflurane anesthesia in a child with congenital long QT syndrome. ( Davy, JM; Frapier, JM; Massad, I; Raczka, F; Saussine, M, 2006) |
| " Propofol was given to provide loss of consciousness during defibrillation shock administration, for induced ventricular fibrillation testing." | 3.70 | Idiopathic prolonged QT interval and QT dispersion: the effects of propofol during implantation of cardioverter-defibrillator. ( Flossos, A; Fraidakis, O; Kanoupakis, E; Manios, E; Michaloudis, D, 1999) |
| " Eight types of ECG-related adverse events were detected in 32 subjects." | 2.77 | [Effect of single doses of HX0507 on QTc intervals in healthy people: a phase I safety and tolerability study]. ( Li, R; Liao, TZ; Liu, J; Xu, J; Yi, XQ; Zhang, WS, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 10 (50.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SH | 1 |
| Lee, JG | 1 |
| Ju, HM | 1 |
| Choi, S | 1 |
| Yang, H | 1 |
| Koo, BN | 1 |
| Kojima, A | 2 |
| Fukushima, Y | 2 |
| Matsuura, H | 2 |
| Itoh, H | 1 |
| Imoto, K | 1 |
| Görges, M | 1 |
| Whyte, SD | 2 |
| Sanatani, S | 1 |
| Dawes, J | 1 |
| Montgomery, CJ | 1 |
| Ansermino, JM | 1 |
| Chang, DJ | 1 |
| Kweon, TD | 2 |
| Nam, SB | 2 |
| Lee, JS | 2 |
| Shin, CS | 1 |
| Park, CH | 1 |
| Han, DW | 2 |
| Kim, DH | 1 |
| Cho, WY | 1 |
| Matsura, M | 1 |
| Fujiwara, Y | 1 |
| Ito, H | 1 |
| Kandatsu, N | 1 |
| Kato, N | 1 |
| Harada, J | 1 |
| Komatsu, T | 1 |
| Tezuka, N | 1 |
| Egawa, H | 1 |
| Fukagawa, D | 1 |
| Yamaguchi, S | 1 |
| Hamaguchi, S | 1 |
| Kitajima, T | 1 |
| Minami, J | 1 |
| Higashijima, U | 1 |
| Terao, Y | 1 |
| Ichinomiya, T | 1 |
| Miura, K | 1 |
| Fukusaki, M | 1 |
| Sumikawa, K | 1 |
| Mandal, B | 1 |
| Kaur, G | 1 |
| Batra, YK | 1 |
| Mahajan, S | 1 |
| Yi, XQ | 1 |
| Li, R | 1 |
| Zhang, WS | 1 |
| Liu, J | 1 |
| Xu, J | 1 |
| Liao, TZ | 1 |
| Michaloudis, D | 2 |
| Kanoupakis, E | 2 |
| Rewari, V | 1 |
| Kaul, H | 1 |
| Booker, PD | 1 |
| Buckley, DG | 1 |
| Yamada, M | 1 |
| Hatakeyama, N | 1 |
| Malykhina, AP | 1 |
| Yamazaki, M | 1 |
| Momose, Y | 1 |
| Akbarali, HI | 1 |
| Saussine, M | 1 |
| Massad, I | 1 |
| Raczka, F | 1 |
| Davy, JM | 1 |
| Frapier, JM | 1 |
| Pelter, MM | 1 |
| Carey, MG | 1 |
| Yu, JH | 1 |
| Hong, K | 1 |
| Cheng, KC | 1 |
| Fraidakis, O | 1 |
| Flossos, A | 1 |
| Manios, E | 1 |
| Kleinsasser, A | 1 |
| Loeckinger, A | 1 |
| Lindner, KH | 1 |
| Keller, C | 1 |
| Boehler, M | 1 |
| Puehringer, F | 1 |
8 trials available for propofol and Long QT Syndrome
| Article | Year |
|---|---|
Propofol prevents further prolongation of QT interval during liver transplantation.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Humans; Liver Transplantation; Living | 2022 |
Effects of fentanyl pretreatment on the QTc interval during propofol induction.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Double-Blind Method; Elect | 2008 |
Effects of target concentration infusion of propofol and tracheal intubation on QTc interval.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Heart Rate; Humans; Infusions, Intravenous; Intubat | 2008 |
Prolongation of QT interval induced by electroconvulsive therapy is attenuated by landiolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anti-Ar | 2010 |
A comparison of the effect on QT interval between thiamylal and propofol during anaesthetic induction*.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Blood Pressure; Electrocardiography; Femal | 2010 |
[Effect of single doses of HX0507 on QTc intervals in healthy people: a phase I safety and tolerability study].
Topics: Adolescent; Adult; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Prodrug | 2012 |
The effects of propofol and sevoflurane on the QT interval and transmural dispersion of repolarization in children.
Topics: Adolescent; Anesthesia, General; Anesthetics, Intravenous; Child; Child, Preschool; Electrocardiogra | 2005 |
Reversing sevoflurane-associated Q-Tc prolongation by changing to propofol.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Electrocardiography; | 2001 |
12 other studies available for propofol and Long QT Syndrome
| Article | Year |
|---|---|
Prediction of anesthetic torsadogenicity using a human ventricular cell model.
Topics: Action Potentials; Anesthetics; Humans; Long QT Syndrome; Propofol; Sevoflurane | 2023 |
A computational analysis of the effect of sevoflurane in a human ventricular cell model of long QT syndrome: Importance of repolarization reserve in the QT-prolonging effect of sevoflurane.
Topics: Action Potentials; Case-Control Studies; Computer Simulation; Delayed Rectifier Potassium Channels; | 2020 |
Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: a retrospective study.
Topics: Administration, Intravenous; Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Child, Presch | 2015 |
Assessment of QT interval and QT dispersion during electroconvulsive therapy using computerized measurements.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Computers; Electrocardiography; Electrocon | 2010 |
Manifestation of Long QT syndrome with normal QTc interval under anesthesia: a case report.
Topics: Adrenergic alpha-Agonists; Anesthesia; Anti-Arrhythmia Agents; Atracurium; Atropine; Cardiopulmonary | 2011 |
Propofol reduces idiopathic prolonged QT interval and QT dispersion during implantation of cardioverter defibrillator.
Topics: Anesthetics, Intravenous; Defibrillators, Implantable; Electrocardiography; Humans; Long QT Syndrome | 2003 |
Sustained ventricular tachycardia in long QT syndrome: is propofol the culprit?
Topics: Anesthetics, Inhalation; Electrocardiography; Humans; Intraoperative Complications; Long QT Syndrome | 2003 |
The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes.
Topics: Animals; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Female; Gene Expression | 2006 |
Torsade de pointes during sevoflurane anesthesia in a child with congenital long QT syndrome.
Topics: Anesthetics, Inhalation; Anticonvulsants; Child; Defibrillators, Implantable; Electrocardiography; H | 2006 |
Long QT syndrome.
Topics: Aged; Anesthetics, Intravenous; Electrocardiography; Female; Humans; Intubation, Intratracheal; Long | 2006 |
[Propofol associated with hypokalemia causes electro storm].
Topics: Adolescent; Anesthesia; Electrocardiography; Humans; Hypokalemia; Long QT Syndrome; Male; Propofol; | 2007 |
Idiopathic prolonged QT interval and QT dispersion: the effects of propofol during implantation of cardioverter-defibrillator.
Topics: Adult; Anesthesia, Local; Anesthetics, Intravenous; Blood Pressure; Cardiac Pacing, Artificial; Cons | 1999 |