propofol has been researched along with Local Neoplasm Recurrence in 17 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol-paravertebral anesthesia (PPA) is a unique combination of paravertebral nerve blocks (PVBs) and propofol that regulates the cellular microenvironment during surgical period." | 8.91 | Perioperative propofol-paravertebral anesthesia decreases the metastasis and progression of breast cancer. ( Chen, L; Chen, X; Lu, P; Shen, HY; Tang, JH; Yang, SJ; Yu, DD; Zhang, XH; Zhao, JH; Zhong, SL, 2015) |
| "Propofol anaesthesia was associated with better survival in hepatocellular carcinoma patients who underwent hepatectomy." | 7.91 | Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study. ( Chan, SM; Huang, YH; Lai, HC; Lee, MS; Lin, C; Lin, KT; Wong, CS; Wu, ZF, 2019) |
| "However, the effects of propofol in bladder cancer (BC) are yet to be fully elucidated." | 5.62 | Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR‑145‑5p/TOP2A axis. ( Chen, Y; Du, Y; Pan, H; Shu, J; Zhang, H; Zhang, X; Zhu, S, 2021) |
| " Disease-free survival increases with the use of propofol in combination with epidural anesthesia in patients who undergo surgery for infiltrating bladder cancer." | 5.56 | Anesthesia in Combination with Propofol Increases Disease-Free Survival in Bladder Cancer Patients Who Undergo Radical Tumor Cystectomy as Compared to Inhalational Anesthetics and Opiate-Based Analgesia. ( Cruz Mañas, J; Diaz Crespo, J; Dominguez Recio, ME; Escalona Belmonte, JJ; Fontaneda Heredia, A; Guerrero Orriach, JL; Herrera Imbroda, B; Malo Manso, A; Raigon Ponferrada, A; Ramirez Aliaga, M; Ramirez Fernandez, A; Rubio Navarro, M; Soriano Perez, AM, 2020) |
| "When propofol was used as the main general anesthetic agent for laparoscopic hepatic resection, the postoperative 2-year recurrence rate decreased in early- and intermediate-stage HCC." | 5.56 | Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma. ( Koo, BW; Lim, DJ; Na, HS; Oh, AY, 2020) |
| "Suspecting the development of pulmonary embolism or anaphylaxis, we performed transesophageal echography; however, no evidence of right heart dilatation was observed, indicating a low possibility of pulmonary embolism." | 5.43 | [A Case of Rocuronium-induced Anaphylaxis in Which Surgery was Subsequently Performed under General Anesthesia without Neuromuscular Blocking Agents]. ( Horiuchi, T; Saito, S; Takazawa, T, 2016) |
| "Propofol-paravertebral anesthesia (PPA) is a unique combination of paravertebral nerve blocks (PVBs) and propofol that regulates the cellular microenvironment during surgical period." | 4.91 | Perioperative propofol-paravertebral anesthesia decreases the metastasis and progression of breast cancer. ( Chen, L; Chen, X; Lu, P; Shen, HY; Tang, JH; Yang, SJ; Yu, DD; Zhang, XH; Zhao, JH; Zhong, SL, 2015) |
| " The aim of this study was to evaluate a potential influence of the anaesthetic method (inhaled anaesthetics versus total-intravenous anaesthesia using propofol) on recurrence-free and overall survival in glioblastoma patients." | 3.96 | The choice of anaesthesia for glioblastoma surgery does not impact the time to recurrence. ( Annecke, T; Grau, SJ; Hampl, J; Löhr, M; Schwab, SG; Taurisano, V; Timmer, M; Trautner, H, 2020) |
| "Propofol anaesthesia was associated with better survival in hepatocellular carcinoma patients who underwent hepatectomy." | 3.91 | Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study. ( Chan, SM; Huang, YH; Lai, HC; Lee, MS; Lin, C; Lin, KT; Wong, CS; Wu, ZF, 2019) |
| "Whether anaesthetic technique for breast cancer surgery influences these factors, and potentially cancer recurrence, remains unknown." | 2.87 | The effect of anaesthetic technique during primary breast cancer surgery on neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and return to intended oncological therapy. ( Buggy, DJ; Burns, D; Ní Eochagáin, A; Riedel, B; Sessler, DI, 2018) |
| "However, the effects of propofol in bladder cancer (BC) are yet to be fully elucidated." | 1.62 | Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR‑145‑5p/TOP2A axis. ( Chen, Y; Du, Y; Pan, H; Shu, J; Zhang, H; Zhang, X; Zhu, S, 2021) |
| " Disease-free survival increases with the use of propofol in combination with epidural anesthesia in patients who undergo surgery for infiltrating bladder cancer." | 1.56 | Anesthesia in Combination with Propofol Increases Disease-Free Survival in Bladder Cancer Patients Who Undergo Radical Tumor Cystectomy as Compared to Inhalational Anesthetics and Opiate-Based Analgesia. ( Cruz Mañas, J; Diaz Crespo, J; Dominguez Recio, ME; Escalona Belmonte, JJ; Fontaneda Heredia, A; Guerrero Orriach, JL; Herrera Imbroda, B; Malo Manso, A; Raigon Ponferrada, A; Ramirez Aliaga, M; Ramirez Fernandez, A; Rubio Navarro, M; Soriano Perez, AM, 2020) |
| "When propofol was used as the main general anesthetic agent for laparoscopic hepatic resection, the postoperative 2-year recurrence rate decreased in early- and intermediate-stage HCC." | 1.56 | Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma. ( Koo, BW; Lim, DJ; Na, HS; Oh, AY, 2020) |
| "Suspecting the development of pulmonary embolism or anaphylaxis, we performed transesophageal echography; however, no evidence of right heart dilatation was observed, indicating a low possibility of pulmonary embolism." | 1.43 | [A Case of Rocuronium-induced Anaphylaxis in Which Surgery was Subsequently Performed under General Anesthesia without Neuromuscular Blocking Agents]. ( Horiuchi, T; Saito, S; Takazawa, T, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 11 (64.71) | 2.80 |
| Authors | Studies |
|---|---|
| Saha, P | 1 |
| Das, A | 1 |
| Chatterjee, N | 1 |
| Chakrabarti, D | 1 |
| Sinha, D | 1 |
| Bogár, L | 1 |
| Dubowitz, J | 1 |
| Ziegler, AI | 1 |
| Beare, R | 1 |
| Jost-Brinkmann, F | 1 |
| Walker, AK | 1 |
| Gillis, RD | 1 |
| Chang, A | 1 |
| Chung, NC | 1 |
| Martin, OA | 1 |
| Hollande, F | 1 |
| Riedel, B | 2 |
| Sloan, EK | 1 |
| Cata, JP | 1 |
| Forget, P | 1 |
| Guerrero Orriach, JL | 1 |
| Raigon Ponferrada, A | 1 |
| Malo Manso, A | 1 |
| Herrera Imbroda, B | 1 |
| Escalona Belmonte, JJ | 1 |
| Ramirez Aliaga, M | 1 |
| Ramirez Fernandez, A | 1 |
| Diaz Crespo, J | 1 |
| Soriano Perez, AM | 1 |
| Fontaneda Heredia, A | 1 |
| Dominguez Recio, ME | 1 |
| Rubio Navarro, M | 1 |
| Cruz Mañas, J | 1 |
| Koo, BW | 1 |
| Lim, DJ | 1 |
| Oh, AY | 1 |
| Na, HS | 1 |
| Grau, SJ | 1 |
| Löhr, M | 1 |
| Taurisano, V | 1 |
| Trautner, H | 1 |
| Timmer, M | 1 |
| Schwab, SG | 1 |
| Hampl, J | 1 |
| Annecke, T | 1 |
| Chang, CY | 1 |
| Wu, MY | 1 |
| Chien, YJ | 1 |
| Su, IM | 1 |
| Wang, SC | 1 |
| Kao, MC | 1 |
| Du, Y | 1 |
| Zhang, X | 1 |
| Zhang, H | 1 |
| Chen, Y | 1 |
| Zhu, S | 1 |
| Shu, J | 1 |
| Pan, H | 1 |
| Hu, C | 1 |
| Iwasaki, M | 1 |
| Liu, Z | 1 |
| Wang, B | 1 |
| Li, X | 1 |
| Lin, H | 1 |
| Li, J | 1 |
| Li, JV | 1 |
| Lian, Q | 1 |
| Ma, D | 2 |
| Zhang, J | 1 |
| Chang, CL | 1 |
| Lu, CY | 1 |
| Chen, HM | 1 |
| Wu, SY | 1 |
| Ní Eochagáin, A | 1 |
| Burns, D | 1 |
| Sessler, DI | 1 |
| Buggy, DJ | 1 |
| Perry, NJS | 1 |
| Buggy, D | 1 |
| Lai, HC | 1 |
| Lee, MS | 1 |
| Lin, C | 1 |
| Lin, KT | 1 |
| Huang, YH | 1 |
| Wong, CS | 1 |
| Chan, SM | 1 |
| Wu, ZF | 1 |
| Chen, X | 1 |
| Lu, P | 1 |
| Chen, L | 1 |
| Yang, SJ | 1 |
| Shen, HY | 1 |
| Yu, DD | 1 |
| Zhang, XH | 1 |
| Zhong, SL | 1 |
| Zhao, JH | 1 |
| Tang, JH | 1 |
| Horiuchi, T | 1 |
| Takazawa, T | 1 |
| Saito, S | 1 |
| Weatherall, AD | 1 |
| Bennett, TR | 1 |
| Lovell, M | 1 |
| Fung, W | 1 |
| de Lima, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Erector Spinae Plane Block With Adjuvant Dexmedetomidine on Chronic Postsurgical Pain in Breast Cancer Patients: a Two-center Randomized Controlled Trial[NCT05494502] | 1,206 participants (Anticipated) | Interventional | 2023-05-23 | Recruiting | |||
| Impact of Novel Thoracic Wall Blocks With Dexmetomidine on Inflammatory Markers Following Breast Cancer Surgery[NCT04860115] | 120 participants (Anticipated) | Interventional | 2021-11-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for propofol and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Impact of anesthetics on oncogenic signaling network: a review on propofol and isoflurane.
Topics: Anesthetics, Inhalation; Humans; Isoflurane; Neoplasm Recurrence, Local; Propofol; Prospective Studi | 2022 |
Anesthesia and Long-term Oncological Outcomes: A Systematic Review and Meta-analysis.
Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics, | 2021 |
Perioperative propofol-paravertebral anesthesia decreases the metastasis and progression of breast cancer.
Topics: Anesthesia; Breast Neoplasms; Female; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nerve | 2015 |
1 trial available for propofol and Local Neoplasm Recurrence
| Article | Year |
|---|---|
The effect of anaesthetic technique during primary breast cancer surgery on neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and return to intended oncological therapy.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Spinal; Breast Neoplasms; C | 2018 |
13 other studies available for propofol and Local Neoplasm Recurrence
| Article | Year |
|---|---|
[Effect of anesthesia on tumor recurrence.]
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Local; Animals; Neoplasm Recurrence, Local; Propof | 2023 |
Type of anesthesia for cancer resection surgery: No differential impact on cancer recurrence in mouse models of breast cancer.
Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics; Anesthetics, Inhalation; Anesthetics, Int | 2023 |
Paravertebral block with propofol anaesthesia does not improve survival compared with sevoflurane anaesthesia for breast cancer surgery: independent discussion of a randomised controlled trial.
Topics: Anesthesia, General; Breast Neoplasms; Humans; Neoplasm Recurrence, Local; Propofol; Sevoflurane | 2020 |
Anesthesia in Combination with Propofol Increases Disease-Free Survival in Bladder Cancer Patients Who Undergo Radical Tumor Cystectomy as Compared to Inhalational Anesthetics and Opiate-Based Analgesia.
Topics: Analgesics, Opioid; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Intravenous; Cyste | 2020 |
Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma.
Topics: Aged; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Hepatocellular; Fem | 2020 |
The choice of anaesthesia for glioblastoma surgery does not impact the time to recurrence.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Brain Neoplasms; Disea | 2020 |
Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR‑145‑5p/TOP2A axis.
Topics: Adult; Aged; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; China; DNA Topoisomerases | 2021 |
Lung but not brain cancer cell malignancy inhibited by commonly used anesthetic propofol during surgery: Implication of reducing cancer recurrence risk.
Topics: A549 Cells; Anesthetics, Intravenous; Antineoplastic Agents; Brain Neoplasms; Cell Movement; Cell Pr | 2021 |
Paravertebral block in regional anesthesia with propofol sedation reduces locoregional recurrence in patients with breast cancer receiving breast conservative surgery compared with volatile inhalational without propofol in general anesthesia.
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, General; Anesthetics, Inhalation; Breast Neoplasms; | 2021 |
Can Anesthesia Influence Cancer Outcomes After Surgery?
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Immunity, Cellular; | 2019 |
Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Hepatocellula | 2019 |
[A Case of Rocuronium-induced Anaphylaxis in Which Surgery was Subsequently Performed under General Anesthesia without Neuromuscular Blocking Agents].
Topics: Adult; Anaphylaxis; Androstanols; Anesthesia, General; Female; Humans; Neoplasm Recurrence, Local; N | 2016 |
Staged intraperitoneal brachytherapy and hyperthermic intraperitoneal chemotherapy in an adolescent: novel anesthetic challenges for pediatric anesthetists.
Topics: Adolescent; Anesthesia, General; Brachytherapy; Combined Modality Therapy; Cytoreduction Surgical Pr | 2017 |