Page last updated: 2024-11-03

propofol and Liver Neoplasms

propofol has been researched along with Liver Neoplasms in 36 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Liver Neoplasms: Tumors or cancer of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"To explore the effects of propofol post-conditioning (PPC) on hepatic ischaemia/reperfusion injury (HIRI) and the potential mechanisms that might be involved in the interaction of Brahma-related gene1(BRG1) and Nuclear-related factor 2(Nrf2)."9.24Propofol post-conditioning alleviates hepatic ischaemia reperfusion injury via BRG1-mediated Nrf2/HO-1 transcriptional activation in human and mice. ( Cai, J; Chen, C; Chen, H; Ge, M; Hei, Z; Jin, Y; Yao, W; Yuan, D; Zhu, Q, 2017)
"The Chinese and English medical databases were searched using a combination of the following search terms: "propofol", "liver cancer", "anesthesia surgery", and "ischemia reperfusion injury" in Chinese or English language, respectively."9.12A meta-analysis and systematic review of propofol on liver ischemia-reperfusion injury protection during hepatocellular carcinoma anesthesia surgery. ( Chen, C; Feng, C; Qian, D, 2021)
"To explore the protective effect and mechanism of ligustrazine (LGT) and propofol (PRO) on peri-operational liver ischemia-reperfusion injury (HIRI)."9.12[Protective effect of ligustrazine and propofol on peri-operational liver ischemia-reperfusion injury]. ( Hu, Z; Lin, LN; Wang, WT; Wu, JZ; Xie, K, 2006)
"To explore the protective effect of propofol on liver during hepatic ischemia/reperfusion injury (HIRI) and its mechanisms in patients undergoing liver surgery."9.11[Protective effect of propofol on liver during ischemia-reperfusion injury in patients undergoing liver surgery]. ( Hu, ZY; Lin, LN; Wang, WT; Wu, JZ; Xie, KJ, 2004)
" Among those patients, 135 patients underwent propofol anesthesia (propofol group), and 145 patients under sevoflurane combined anesthesia (sevoflurane group)."7.91Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy. ( Hou, JF; Xiao, CL, 2019)
"Propofol anaesthesia was associated with better survival in hepatocellular carcinoma patients who underwent hepatectomy."7.91Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study. ( Chan, SM; Huang, YH; Lai, HC; Lee, MS; Lin, C; Lin, KT; Wong, CS; Wu, ZF, 2019)
"Propofol is one of the most extensively used intravenous anaesthetic agents, which has been found to improve the surgical intervention outcome of several types of cancer, including hepatocellular carcinoma (HCC)."7.91Propofol-induced miR-219-5p inhibits growth and invasion of hepatocellular carcinoma through suppression of GPC3-mediated Wnt/β-catenin signalling activation. ( Chen, X; Chen, Z; Deng, Z; Gong, T; Huang, S; Liu, M; Luo, R; Ning, X; Xu, Y; Zhou, B, 2019)
"We previously confirmed that propofol directly inhibited the viability, proliferation, and invasiveness of hepatocellular carcinoma cells in vitro."7.80Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells. ( Jin, HY; Jin, TT; Shan, WF; Wu, GQ; Xiong, XX; Zhang, J; Zhu, SM, 2014)
"Propofol decreases hepatocellular carcinoma cell invasiveness, which is partly due to the down-regulation of MMP-9 expression by miR-199a."7.79Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. ( Feng, ZY; Wu, GQ; Zhang, D; Zhang, J; Zhu, SM, 2013)
"The preparation and characterization of a novel escheriosomal nanoparticle formulation of a potent anticancer conjugate, 2,6-diisopropylphenol-linoleic acid (2,6P-LA), and evaluation of its anticancer efficacy against diethyl nitrosamine-induced hepatocellular carcinoma (HCC) in BALB/c mice."7.79Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma. ( Jabeen, M; Khan, AA; Owais, M, 2013)
"Propofol could inhibit cell proliferation, migration, and invasion and induce apoptosis via suppression on SHH to inactivate the SHH pathway."5.91Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway. ( Lai, S; Liu, Y; Wang, W; Wu, J; Wu, T; Yang, L; Zhou, F, 2023)
"However, liver cancer is mostly found at an advanced stage, is difficult to remove by surgery, and has a very high recurrence rate after surgery."5.62The effect of propofol on the proliferation and apoptosis of hepatocellular carcinoma cells through TGF-Β1/Smad2 signaling pathway. ( Li, Z; Liu, H; Tan, H; Zhang, Y, 2021)
"Propofol is an intravenous anesthetic extensively used in clinical."5.56Propofol exerts anticancer activity on hepatocellular carcinoma cells by raising lncRNA DGCR5. ( Sun, H; Sun, Y, 2020)
"When propofol was used as the main general anesthetic agent for laparoscopic hepatic resection, the postoperative 2-year recurrence rate decreased in early- and intermediate-stage HCC."5.56Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma. ( Koo, BW; Lim, DJ; Na, HS; Oh, AY, 2020)
"Propofol is a commonly used drug for the induction and maintenance of anesthesia."5.56Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. ( Feng, Y; Jin, Y; Liu, J; Song, F, 2020)
"Propofol treatment downregulated the protein levels of Vimentin, MMP-2, and MMP-9 while increasing that of E-cadherin."5.51Propofol inhibits proliferation, migration, and invasion of hepatocellular carcinoma cells by downregulating Twist. ( Fu, Y; Yang, T; Zheng, H, 2019)
"To explore the effects of propofol post-conditioning (PPC) on hepatic ischaemia/reperfusion injury (HIRI) and the potential mechanisms that might be involved in the interaction of Brahma-related gene1(BRG1) and Nuclear-related factor 2(Nrf2)."5.24Propofol post-conditioning alleviates hepatic ischaemia reperfusion injury via BRG1-mediated Nrf2/HO-1 transcriptional activation in human and mice. ( Cai, J; Chen, C; Chen, H; Ge, M; Hei, Z; Jin, Y; Yao, W; Yuan, D; Zhu, Q, 2017)
"The Chinese and English medical databases were searched using a combination of the following search terms: "propofol", "liver cancer", "anesthesia surgery", and "ischemia reperfusion injury" in Chinese or English language, respectively."5.12A meta-analysis and systematic review of propofol on liver ischemia-reperfusion injury protection during hepatocellular carcinoma anesthesia surgery. ( Chen, C; Feng, C; Qian, D, 2021)
"To explore the protective effect and mechanism of ligustrazine (LGT) and propofol (PRO) on peri-operational liver ischemia-reperfusion injury (HIRI)."5.12[Protective effect of ligustrazine and propofol on peri-operational liver ischemia-reperfusion injury]. ( Hu, Z; Lin, LN; Wang, WT; Wu, JZ; Xie, K, 2006)
"To explore the protective effect of propofol on liver during hepatic ischemia/reperfusion injury (HIRI) and its mechanisms in patients undergoing liver surgery."5.11[Protective effect of propofol on liver during ischemia-reperfusion injury in patients undergoing liver surgery]. ( Hu, ZY; Lin, LN; Wang, WT; Wu, JZ; Xie, KJ, 2004)
"Propofol has been previously demonstrated to relieve hepatocellular carcinoma (HCC)."4.02Propofol Ameliorates the Proliferation and Epithelial-Mesenchymal Transition of Hepatoma Carcinoma Cells via Non-Coding RNA Activated by DNA Damage (NORAD)/microRNA (miR)-556-3p/Migration and Invasion Enhancer 1 (MIEN1) Axis. ( Guan, E; Li, H; Liu, Y; Luo, K; Wang, X, 2021)
"Compared to propofol and general anesthesia, midazolam/fentanyl sedation was associated with an increased periprocedural perception of pain and lower local tumor progression-free survival."3.91Propofol Compared to Midazolam Sedation and to General Anesthesia for Percutaneous Microwave Ablation in Patients with Hepatic Malignancies: A Single-Center Comparative Analysis of Three Historical Cohorts. ( de Jong, MC; de Vries, JJJ; Geboers, B; Gerçek, CC; Hoedemaker-Boon, CJ; Meijerink, MR; Nieuwenhuizen, S; Puijk, RS; Ruarus, AH; Scheffer, HJ; Thöne-Passchier, DH; van den Tol, PMP; Vroomen, LGPH; Ziedses des Plantes, V, 2019)
"Propofol anaesthesia was associated with better survival in hepatocellular carcinoma patients who underwent hepatectomy."3.91Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study. ( Chan, SM; Huang, YH; Lai, HC; Lee, MS; Lin, C; Lin, KT; Wong, CS; Wu, ZF, 2019)
"Propofol is one of the most extensively used intravenous anaesthetic agents, which has been found to improve the surgical intervention outcome of several types of cancer, including hepatocellular carcinoma (HCC)."3.91Propofol-induced miR-219-5p inhibits growth and invasion of hepatocellular carcinoma through suppression of GPC3-mediated Wnt/β-catenin signalling activation. ( Chen, X; Chen, Z; Deng, Z; Gong, T; Huang, S; Liu, M; Luo, R; Ning, X; Xu, Y; Zhou, B, 2019)
" Among those patients, 135 patients underwent propofol anesthesia (propofol group), and 145 patients under sevoflurane combined anesthesia (sevoflurane group)."3.91Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy. ( Hou, JF; Xiao, CL, 2019)
"We previously confirmed that propofol directly inhibited the viability, proliferation, and invasiveness of hepatocellular carcinoma cells in vitro."3.80Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells. ( Jin, HY; Jin, TT; Shan, WF; Wu, GQ; Xiong, XX; Zhang, J; Zhu, SM, 2014)
"Propofol decreases hepatocellular carcinoma cell invasiveness, which is partly due to the down-regulation of MMP-9 expression by miR-199a."3.79Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. ( Feng, ZY; Wu, GQ; Zhang, D; Zhang, J; Zhu, SM, 2013)
"The preparation and characterization of a novel escheriosomal nanoparticle formulation of a potent anticancer conjugate, 2,6-diisopropylphenol-linoleic acid (2,6P-LA), and evaluation of its anticancer efficacy against diethyl nitrosamine-induced hepatocellular carcinoma (HCC) in BALB/c mice."3.79Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma. ( Jabeen, M; Khan, AA; Owais, M, 2013)
"For patients with liver cancer, monitoring the depth of anesthesia with Narcotrend on microwave coagulation can contribute to lower dosage of propofol and shorten duration of recovery during total intravenous anesthesia with propofol and fentanyl."2.75[Application of a narcotrend-assisted anesthesia in-depth monitor in the microwave coagulation for liver cancer during total intravenous anesthesia with propofol and fentanyl]. ( Huang, W; Lai, JL; Lai, RC; Lu, YL; Wang, XD; Xie, JD; Xu, MX, 2010)
"Propofol could inhibit cell proliferation, migration, and invasion and induce apoptosis via suppression on SHH to inactivate the SHH pathway."1.91Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway. ( Lai, S; Liu, Y; Wang, W; Wu, J; Wu, T; Yang, L; Zhou, F, 2023)
"50 samples of liver cancer and para-cancer tissues in patients were collected and the difference in the expression of miR-195-5p was then analyzed."1.72Propofol enhances the lethality of cisplatin on liver cancer cells by up-regulating miR-195-5p. ( Gao, L; Zhang, X, 2022)
"However, liver cancer is mostly found at an advanced stage, is difficult to remove by surgery, and has a very high recurrence rate after surgery."1.62The effect of propofol on the proliferation and apoptosis of hepatocellular carcinoma cells through TGF-Β1/Smad2 signaling pathway. ( Li, Z; Liu, H; Tan, H; Zhang, Y, 2021)
"The apoptosis and metastasis were measured by flow cytometry and transwell assays."1.56Exosomal lncRNA H19 promotes the progression of hepatocellular carcinoma treated with Propofol via miR-520a-3p/LIMK1 axis. ( Ai, Y; He, J; Liu, J; Wang, D; Xing, N; Yang, J; Yang, T; Zhao, H, 2020)
"Propofol is a commonly used drug for the induction and maintenance of anesthesia."1.56Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. ( Feng, Y; Jin, Y; Liu, J; Song, F, 2020)
" Further analysis showed that intraoperative propofol dosage was correlated with ALT, AST, and miR-148a-3p after hepatectomy."1.56Diagnostic Value of Peripheral Blood miR-148a-3p in Patients with Liver Injury After Hepatectomy Under General Anesthesia with Propofol. ( Chen, Y; Duan, J, 2020)
"When propofol was used as the main general anesthetic agent for laparoscopic hepatic resection, the postoperative 2-year recurrence rate decreased in early- and intermediate-stage HCC."1.56Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma. ( Koo, BW; Lim, DJ; Na, HS; Oh, AY, 2020)
"Propofol is an intravenous anesthetic extensively used in clinical."1.56Propofol exerts anticancer activity on hepatocellular carcinoma cells by raising lncRNA DGCR5. ( Sun, H; Sun, Y, 2020)
"Propofol treatment downregulated the protein levels of Vimentin, MMP-2, and MMP-9 while increasing that of E-cadherin."1.51Propofol inhibits proliferation, migration, and invasion of hepatocellular carcinoma cells by downregulating Twist. ( Fu, Y; Yang, T; Zheng, H, 2019)
"Propofol is a commonly used anaesthetic with controversial effects on cancer cells."1.48Propofol Inhibits Proliferation, Migration, Invasion and Promotes Apoptosis Through Down-Regulating miR-374a in Hepatocarcinoma Cell Lines. ( Hu, ZH; Li, Y; Li, ZW; Liu, SQ; Liu, Z; Zhang, JL, 2018)
"Propofol seems to be a promising drug in treating the terminal agitated state that can be associated with the dying process."1.29Propofol in terminal care. ( De Conno, F; Mercadante, S; Ripamonti, C, 1995)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (8.33)18.2507
2000's4 (11.11)29.6817
2010's16 (44.44)24.3611
2020's13 (36.11)2.80

Authors

AuthorsStudies
Gao, L1
Zhang, X1
Liu, Y3
Wang, X1
Li, H1
Guan, E1
Luo, K1
Wu, J2
Zhou, F2
Lai, S2
Wang, W2
Wu, T2
Yang, L2
Sun, Y1
Sun, H1
Qi, J1
Wu, Q1
Zhu, X1
Zhang, S1
Chen, X2
Chen, W1
Sun, Z1
Zhu, M1
Miao, C1
Koo, BW1
Lim, DJ1
Oh, AY1
Na, HS1
Chen, Y1
Duan, J1
Fei, G2
Cao, M2
Ge, C2
Cui, L1
Song, F1
Liu, J2
Feng, Y1
Jin, Y2
Wang, D1
Xing, N1
Yang, T2
Zhao, H1
He, J1
Ai, Y1
Yang, J1
Xie, Y1
Feng, C1
Qian, D1
Chen, C2
Li, Z1
Liu, H1
Zhang, Y1
Tan, H1
Li, J1
Liu, M2
Zeng, B1
Wang, Z1
Ge, M1
Chen, H1
Zhu, Q1
Cai, J1
Yuan, D1
Yao, W1
Hei, Z1
Liu, SQ1
Zhang, JL1
Li, ZW1
Hu, ZH1
Liu, Z1
Li, Y2
Hou, JF1
Xiao, CL1
Zheng, H1
Fu, Y1
Gong, T1
Ning, X1
Deng, Z1
Zhou, B1
Huang, S1
Xu, Y1
Chen, Z1
Luo, R1
Lai, HC1
Lee, MS1
Lin, C1
Lin, KT1
Huang, YH1
Wong, CS1
Chan, SM1
Wu, ZF1
Puijk, RS1
Ziedses des Plantes, V1
Nieuwenhuizen, S1
Ruarus, AH1
Vroomen, LGPH1
de Jong, MC1
Geboers, B1
Hoedemaker-Boon, CJ1
Thöne-Passchier, DH1
Gerçek, CC1
de Vries, JJJ1
van den Tol, PMP1
Scheffer, HJ1
Meijerink, MR1
Zhang, J2
Zhang, D1
Wu, GQ2
Feng, ZY1
Zhu, SM2
Yang, LL1
Ji, JS1
Wu, W1
Lei, LP1
Zhao, ZW1
Shao, GL1
Zheng, JP1
Shan, WF1
Jin, TT1
Xiong, XX1
Jin, HY1
Lu, L1
Zhou, J1
Shi, J1
Peng, XJ1
Qi, XX1
Wang, Y1
Li, FY1
Zhou, FY1
Liu, L1
Liu, ZQ1
Joung, KW1
Choi, SS1
Jang, DM1
Kong, YG1
Lee, HM1
Shim, JH1
Won, HJ1
Shin, YM1
Kim, PN1
Song, MH1
Lai, RC1
Lu, YL1
Huang, W2
Xu, MX2
Lai, JL1
Xie, JD1
Wang, XD1
Cheung Ning, M1
Karmakar, MK1
Khan, AA2
Jabeen, M1
Owais, M1
Lin, LN2
Wang, WT2
Wu, JZ2
Hu, ZY1
Xie, KJ1
Hu, Z1
Xie, K1
Long, YH1
Li, W1
Wang, J1
Chen, MS1
Figiel, M1
Allritz, C1
Lehmann, C1
Engele, J1
Bichel, T1
Joris, J1
Jacquet, N1
Lamy, M1
Mercadante, S1
De Conno, F1
Ripamonti, C1
Konstantinidou, AS1
Balamoutsos, NG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Erector Spina Plain (ESP) Block on Patient Outcomes in Patients With Liver Tumor Undergoing Radiofrequency Ablation[NCT05009550]30 participants (Anticipated)Interventional2021-05-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for propofol and Liver Neoplasms

ArticleYear
A meta-analysis and systematic review of propofol on liver ischemia-reperfusion injury protection during hepatocellular carcinoma anesthesia surgery.
    Annals of palliative medicine, 2021, Volume: 10, Issue:6

    Topics: Anesthesia; Carcinoma, Hepatocellular; China; Humans; Liver; Liver Neoplasms; Propofol; Reperfusion

2021
Total intravenous anesthesia in South-African genetic porphyria (variegate porphyria).
    Acta anaesthesiologica Belgica, 1993, Volume: 44, Issue:1

    Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Female; Humans; Liver Neoplasms; Porphyrias, He

1993

Trials

7 trials available for propofol and Liver Neoplasms

ArticleYear
Propofol post-conditioning alleviates hepatic ischaemia reperfusion injury via BRG1-mediated Nrf2/HO-1 transcriptional activation in human and mice.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Antioxidants; Cell Line; DNA Helicases; Drug Repositioning; Female

2017
[Clinical observation of remifentanyl and propofol injection in total intravenous anesthesia for percutaneous radiofrequency ablation].
    Zhonghua yi xue za zhi, 2013, Dec-03, Volume: 93, Issue:45

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Catheter Ablation; Female; Humans; Liver N

2013
Comparative Effects of Dexmedetomidine and Propofol on US-Guided Radiofrequency Ablation of Hepatic Neoplasm Under Monitored Anesthesia Care: A Randomized Controlled Study.
    Medicine, 2015, Volume: 94, Issue:32

    Topics: Analgesics; Catheter Ablation; Dexmedetomidine; Female; Hemodynamics; Humans; Liver Neoplasms; Male;

2015
[Application of a narcotrend-assisted anesthesia in-depth monitor in the microwave coagulation for liver cancer during total intravenous anesthesia with propofol and fentanyl].
    Chinese journal of cancer, 2010, Volume: 29, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Electrocoagulation; Fentanyl; Hemody

2010
[Protective effect of propofol on liver during ischemia-reperfusion injury in patients undergoing liver surgery].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2004, Volume: 16, Issue:1

    Topics: Adult; Carboxypeptidases; Female; Free Radical Scavengers; Humans; Lipid Peroxides; Liver; Liver Neo

2004
[Protective effect of ligustrazine and propofol on peri-operational liver ischemia-reperfusion injury].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2006, Volume: 26, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Drug Therapy, Combination; Female; Humans; Lipid Peroxides; Liv

2006
[Application of total intravenous anesthesia with remifentanyl and propofol to radiofrequency ablation].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:3

    Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Blood Pressure; Carbon Dioxide; Carcinoma, Hep

2007

Other Studies

27 other studies available for propofol and Liver Neoplasms

ArticleYear
Propofol enhances the lethality of cisplatin on liver cancer cells by up-regulating miR-195-5p.
    Tissue & cell, 2022, Volume: 74

    Topics: Cell Death; Cell Line, Tumor; Cisplatin; Gene Expression Regulation, Neoplastic; Humans; Liver Neopl

2022
Propofol Ameliorates the Proliferation and Epithelial-Mesenchymal Transition of Hepatoma Carcinoma Cells via Non-Coding RNA Activated by DNA Damage (NORAD)/microRNA (miR)-556-3p/Migration and Invasion Enhancer 1 (MIEN1) Axis.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2021, Volume: 40, Issue:4

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; DNA Damage; Epithelial-Mesench

2021
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway.
    Pharmacology, 2023, Volume: 108, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hedgehog Proteins; Humans; Liver Ne

2023
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway.
    Pharmacology, 2023, Volume: 108, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hedgehog Proteins; Humans; Liver Ne

2023
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway.
    Pharmacology, 2023, Volume: 108, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hedgehog Proteins; Humans; Liver Ne

2023
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway.
    Pharmacology, 2023, Volume: 108, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hedgehog Proteins; Humans; Liver Ne

2023
Propofol exerts anticancer activity on hepatocellular carcinoma cells by raising lncRNA DGCR5.
    Journal of cellular physiology, 2020, Volume: 235, Issue:3

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expr

2020
Propofol attenuates the adhesion of tumor and endothelial cells through inhibiting glycolysis in human umbilical vein endothelial cells.
    Acta biochimica et biophysica Sinica, 2019, Nov-18, Volume: 51, Issue:11

    Topics: Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carcinoma, Hepatocellular; Cell Adhesion; Cell A

2019
Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2020, Volume: 29, Issue:5

    Topics: Aged; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Hepatocellular; Fem

2020
Diagnostic Value of Peripheral Blood miR-148a-3p in Patients with Liver Injury After Hepatectomy Under General Anesthesia with Propofol.
    Clinical laboratory, 2020, Mar-01, Volume: 66, Issue:3

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Biomarkers; Female; Hepatectomy; Humans;

2020
Propofol suppresses hepatocellular carcinoma by inhibiting NET1 through downregulating ERK/VEGF signaling pathway.
    Scientific reports, 2020, 07-08, Volume: 10, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Down-Regulation; Drug Screening Assays,

2020
Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458.
    International journal of molecular medicine, 2020, Volume: 46, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Prol

2020
Exosomal lncRNA H19 promotes the progression of hepatocellular carcinoma treated with Propofol via miR-520a-3p/LIMK1 axis.
    Cancer medicine, 2020, Volume: 9, Issue:19

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cocu

2020
Different anaesthesia methods affect the development of hepatoblastoma after platelet activation.
    International journal of experimental pathology, 2021, Volume: 102, Issue:1

    Topics: Animals; Hepatoblastoma; Hypnotics and Sedatives; Liver Neoplasms; Pentobarbital; Platelet Activatio

2021
The effect of propofol on the proliferation and apoptosis of hepatocellular carcinoma cells through TGF-Β1/Smad2 signaling pathway.
    Bioengineered, 2021, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Female; Hep G2 Cells; Humans; Liv

2021
Propofol induces hepatocellular carcinoma cell apoptosis via regulating miR-105/JAK2/STAT3 axis.
    Cytokine, 2021, Volume: 148

    Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, N

2021
Propofol Inhibits Proliferation, Migration, Invasion and Promotes Apoptosis Through Down-Regulating miR-374a in Hepatocarcinoma Cell Lines.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:6

    Topics: 3' Untranslated Regions; Antagomirs; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Movement;

2018
Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:2

    Topics: Adult; Amyloid beta-Peptides; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcino

2019
Propofol inhibits proliferation, migration, and invasion of hepatocellular carcinoma cells by downregulating Twist.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:8

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relati

2019
Propofol-induced miR-219-5p inhibits growth and invasion of hepatocellular carcinoma through suppression of GPC3-mediated Wnt/β-catenin signalling activation.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:10

    Topics: Anesthetics, Intravenous; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell

2019
Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study.
    British journal of anaesthesia, 2019, Volume: 123, Issue:2

    Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Hepatocellula

2019
Propofol Compared to Midazolam Sedation and to General Anesthesia for Percutaneous Microwave Ablation in Patients with Hepatic Malignancies: A Single-Center Comparative Analysis of Three Historical Cohorts.
    Cardiovascular and interventional radiology, 2019, Volume: 42, Issue:11

    Topics: Ablation Techniques; Aged; Anesthesia, General; Cohort Studies; Female; Humans; Hypnotics and Sedati

2019
Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2013, Volume: 12, Issue:3

    Topics: Anesthetics, Intravenous; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Dose-Response Rel

2013
Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells.
    Journal of translational medicine, 2014, Oct-09, Volume: 12

    Topics: Animals; Antineoplastic Agents; Biological Transport; Carcinoma, Hepatocellular; Cell Line, Tumor; C

2014
Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adult; Camptothecin; Carcinoma, Hepatocellular; Genistein; Glucuronosyltransferase; Humans; Inactiva

2015
Right thoracic paravertebral anaesthesia for percutaneous radiofrequency ablation of liver tumours.
    The British journal of radiology, 2011, Volume: 84, Issue:1005

    Topics: Adult; Aged; Analgesics; Catheter Ablation; Female; Fentanyl; Fluoroscopy; Humans; Infusions, Intrav

2011
Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma.
    Nanomedicine (London, England), 2013, Volume: 8, Issue:8

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; DNA Fragmentation; Humans; Linoleic Acid;

2013
Gap junctional control of glial glutamate transporter expression.
    Molecular and cellular neurosciences, 2007, Volume: 35, Issue:1

    Topics: Animals; Anticonvulsants; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Connexin 43;

2007
Propofol in terminal care.
    Journal of pain and symptom management, 1995, Volume: 10, Issue:8

    Topics: Delirium; Humans; Hypnotics and Sedatives; Liver Neoplasms; Male; Middle Aged; Myoclonus; Palliative

1995
Paraplegia in a patient who by chance missed the insertion of an epidural catheter.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:5

    Topics: Anesthesia, Epidural; Anesthesia, Intravenous; Anesthetics, Intravenous; Antineoplastic Combined Che

1996