propofol has been researched along with Leucocythaemia in 7 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to determine whether families of children with acute leukemia prefer propofol alone or propofol plus fentanyl for lumbar puncture (LP) sedation." | 9.13 | Sedative preference of families for lumbar punctures in children with acute leukemia: propofol alone or propofol and fentanyl. ( Cechvala, MM; Christenson, D; Eickhoff, JC; Hollman, GA, 2008) |
| "The use of propofol is controversial in patients with a history of acute pancreatitis or those taking drugs, including certain chemotherapeutic drugs, that are associated with pancreatitis." | 7.75 | Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk? ( Crawford, MW; Lopez, AV; Pehora, C, 2009) |
| " The purpose of this study was to determine whether families of children with acute leukemia prefer propofol alone or propofol plus fentanyl for lumbar puncture (LP) sedation." | 5.13 | Sedative preference of families for lumbar punctures in children with acute leukemia: propofol alone or propofol and fentanyl. ( Cechvala, MM; Christenson, D; Eickhoff, JC; Hollman, GA, 2008) |
| "The pain and distress ratings of patients undergoing BMAs (n = 73) and LPs (n = 105) were examined in a comparison of 3 different interventions: (1) a topical eutectic mixture of lidocaine and prilocaine (EMLA cream), (2) oral midazolam and EMLA cream, or (3) propofol/fentanyl general anesthesia." | 5.10 | Pain and distress from bone marrow aspirations and lumbar punctures. ( Doran, NH; Frost, JD; Holdsworth, MT; Mathew, P; Moro, MA; Pankey, JM; Phillips, J; Raisch, DW; Winter, SS, 2003) |
| "Propofol is one of the most widely clinically used intravenous anesthetic, and it induces apoptosis in human and murine leukemia cell lines." | 3.79 | Propofol induces DNA damage in mouse leukemic monocyte macrophage RAW264.7 cells. ( Chiang, JH; Chung, JG; Hsia, TC; Hsu, SC; Liu, KC; Wu, KC; Wu, RS; Yang, JS; Yang, ST, 2013) |
| "The use of propofol is controversial in patients with a history of acute pancreatitis or those taking drugs, including certain chemotherapeutic drugs, that are associated with pancreatitis." | 3.75 | Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk? ( Crawford, MW; Lopez, AV; Pehora, C, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, KC | 1 |
| Yang, ST | 1 |
| Hsu, SC | 1 |
| Chiang, JH | 1 |
| Hsia, TC | 1 |
| Yang, JS | 1 |
| Liu, KC | 1 |
| Wu, RS | 1 |
| Chung, JG | 1 |
| Crawford, MW | 1 |
| Pehora, C | 1 |
| Lopez, AV | 1 |
| Holdsworth, MT | 1 |
| Raisch, DW | 1 |
| Winter, SS | 1 |
| Frost, JD | 1 |
| Moro, MA | 1 |
| Doran, NH | 1 |
| Phillips, J | 1 |
| Pankey, JM | 1 |
| Mathew, P | 1 |
| Barbi, E | 1 |
| Badina, L | 1 |
| Marchetti, F | 1 |
| Vecchi, R | 1 |
| Giuseppin, I | 1 |
| Bruno, I | 1 |
| Zanazzo, G | 1 |
| Sarti, A | 1 |
| Ventura, A | 1 |
| Ray, NP | 1 |
| Cechvala, MM | 1 |
| Christenson, D | 1 |
| Eickhoff, JC | 1 |
| Hollman, GA | 1 |
| Harling, DW | 1 |
| Harrison, DA | 1 |
| Dorman, T | 1 |
| Barker, I | 1 |
3 trials available for propofol and Leucocythaemia
| Article | Year |
|---|---|
Pain and distress from bone marrow aspirations and lumbar punctures.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Biopsy, Needle; Bon | 2003 |
Sedative preference of families for lumbar punctures in children with acute leukemia: propofol alone or propofol and fentanyl.
Topics: Acute Disease; Adolescent; Anxiety; Child; Child, Preschool; Cross-Over Studies; Double-Blind Method | 2008 |
A comparison of thiopentone-isoflurane anaesthesia vs propofol infusion in children having repeat minor haematological procedures.
Topics: Acute Disease; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Biopsy, Nee | 1997 |
4 other studies available for propofol and Leucocythaemia
| Article | Year |
|---|---|
Propofol induces DNA damage in mouse leukemic monocyte macrophage RAW264.7 cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; DNA Repair; Gene Expre | 2013 |
Drug-induced acute pancreatitis in children receiving chemotherapy for acute leukemia: does propofol increase the risk?
Topics: Acute Disease; Adolescent; Anesthesia, General; Anesthetics, Intravenous; Antineoplastic Agents; Chi | 2009 |
Attitudes of children with leukemia toward repeated deep sedations with propofol.
Topics: Adolescent; Age Factors; Anxiety; Attitude; Bone Marrow Examination; Child; Child, Preschool; Fear; | 2005 |
Pediatric "sedation" protocols: exchanging old problems for new ones.
Topics: Anesthesia, General; Child; Fentanyl; Humans; Hypnotics and Sedatives; Leukemia; Propofol; Spinal Pu | 2008 |