propofol has been researched along with Lesch-Nyhan Syndrome in 3 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Lesch-Nyhan Syndrome: An inherited disorder transmitted as a sex-linked trait and caused by a deficiency of an enzyme of purine metabolism; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE. Affected individuals are normal in the first year of life and then develop psychomotor retardation, extrapyramidal movement disorders, progressive spasticity, and seizures. Self-destructive behaviors such as biting of fingers and lips are seen frequently. Intellectual impairment may also occur but is typically not severe. Elevation of uric acid in the serum leads to the development of renal calculi and gouty arthritis. (Menkes, Textbook of Child Neurology, 5th ed, pp127)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lesch-Nyhan syndrome (LNS) is an X-linked recessive disorder presenting with uric acid overproduction, neurocognitive disability, and behavioral disturbances." | 7.96 | Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report. ( Jeon, S; Jung, SM; Lee, J, 2020) |
| "Lesch-Nyhan syndrome (LNS) is an X-linked recessive disorder presenting with uric acid overproduction, neurocognitive disability, and behavioral disturbances." | 3.96 | Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report. ( Jeon, S; Jung, SM; Lee, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, J | 1 |
| Jung, SM | 1 |
| Jeon, S | 1 |
| Fernández, E | 1 |
| Barrio, E | 1 |
| Luque, M | 1 |
| De Miguel, A | 1 |
| Fernández, C | 1 |
| Cruz, P | 1 |
| Williams, KS | 1 |
| Hankerson, JG | 1 |
| Ernst, M | 1 |
| Zametkin, A | 1 |
1 trial available for propofol and Lesch-Nyhan Syndrome
| Article | Year |
|---|---|
Use of propofol anesthesia during outpatient radiographic imaging studies in patients with Lesch-Nyhan syndrome.
Topics: Adolescent; Adult; Ambulatory Care; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Ge | 1997 |
2 other studies available for propofol and Lesch-Nyhan Syndrome
| Article | Year |
|---|---|
Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report.
Topics: Administration, Intravenous; Adolescent; Anesthesia Recovery Period; Anesthesia, General; Humans; Hy | 2020 |
[Anaesthesia in a patient with Lesch-Nyhan syndrome].
Topics: Airway Management; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracuriu | 2012 |