propofol has been researched along with Kidney Failure, Chronic in 24 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary objective of this study was to compare the pharmacokinetics of dexmedetomidine in patients with end-stage renal failure and secondary hyperparathyroidism with those in normal individuals." | 7.88 | Pharmacokinetics of dexmedetomidine administered to patients with end-stage renal failure and secondary hyperparathyroidism undergoing general anaesthesia. ( Huang, XH; Li, R; Li, Y; Liu, QW; Zhang, MZ; Zhang, Y; Zhong, W, 2018) |
| "PRIS causing hyperkalemia is a well-known clinical entity." | 5.43 | Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients. ( El-Ali, IM; Onuchic, A; Trivedi, RD; Virmani, S, 2016) |
| "The primary objective of this study was to compare the pharmacokinetics of dexmedetomidine in patients with end-stage renal failure and secondary hyperparathyroidism with those in normal individuals." | 3.88 | Pharmacokinetics of dexmedetomidine administered to patients with end-stage renal failure and secondary hyperparathyroidism undergoing general anaesthesia. ( Huang, XH; Li, R; Li, Y; Liu, QW; Zhang, MZ; Zhang, Y; Zhong, W, 2018) |
| "We aim to describe management of a patient receiving renal transplantation for chronic renal failure due to Alport syndrome with low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic." | 3.83 | Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report. ( Brazzi, L; Bretto, P; Donadio, PP; Gobbi, F; Sales, G, 2016) |
| "Results: ESRD patients receiving propofol TCI had significantly less reduction in blood pressure than those receiving sevoflurane inhalation (p < 0." | 3.11 | Application of Propofol Target-Controlled Infusion for Optimized Hemodynamic Status in ESRD Patients Receiving Arteriovenous Access Surgery: A Randomized Controlled Trial. ( Chen, PC; Chen, PN; Huang, TW; Lin, WC; Lu, IC; Lu, WL; Tse, J, 2022) |
| "Among the 2576 cases in ESRD patients, 1374 were in the TIVA group and 1202 were in the volatile group." | 3.01 | The influence of propofol-based total intravenous anesthesia on postoperative outcomes in end-stage renal disease patients: A retrospective observation study. ( Cho, HB; Chung, JW; Jang, YS; Kim, MG; Kim, SH; Lee, HK; Park, S; Park, SY; Song, S; Yoo, JH, 2021) |
| "The Ce values of propofol at the time of loss of consciousness were 4." | 1.62 | Potency of propofol for inducing loss of consciousness in end-stage kidney disease patients. ( Cho, HB; Chung, JW; Han, KS; Jun, MR; Kim, MG; Kim, SH; Park, JE; Park, SY; Song, S; Yoo, JH, 2021) |
| "PRIS causing hyperkalemia is a well-known clinical entity." | 1.43 | Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients. ( El-Ali, IM; Onuchic, A; Trivedi, RD; Virmani, S, 2016) |
| "Propofol was administrated with our TCI system at the target blood concentration of 4 microg x ml(-1) for three hours." | 1.35 | [Evaluation of target-controlled infusion for propofol in patients with chronic renal failure undergoing living-related renal transplantation]. ( Igarashi, T; Ikeda, M; Iwakiri, H; Nagata, O; Ozaki, M, 2009) |
| "Rocuronium 0." | 1.33 | Pharmacodynamics of rocuronium 0.3 mg kg(-1) in adult patients with and without renal failure. ( De Boer, H; Driessen, JJ; Robertson, EN; Scheffer, GJ; Vogt, M, 2005) |
| "Propofol was administered through the Diprifusor TCI system (Astra Zeneca) with the target concentration of propofol for induction set at 3 micrograms/mL for group A patients and 2." | 1.32 | [Predictive capability of the TCI Diprifusor system in patients with terminal chronic renal insufficiency]. ( Baxarias Gascón, P; Queraltó Companyo, JM; Sabaté Tenas, S; Soler Corbera, J, 2003) |
| "Propofol was administered at 0." | 1.31 | Evaluation of induction doses of propofol: comparison between endstage renal disease and normal renal function patients. ( Goyal, P; Pandey, CK; Puri, GD; Srivastva, S, 2002) |
| "Atracurium is administered to ten chronic renal failure patients in the course of kidney transplantation, abiding to all requirements and doses recommended by the company." | 1.30 | [The use of atracurium besylate (Tracrium) in patients undergoing kidney transplantation]. ( Bovianska, N, 1997) |
| "Propofol conjugates were determined after hydrolysis with beta glucuronidase or HCl." | 1.29 | Pharmacokinetics of propofol and its conjugates after continuous infusion in normal and in renal failure patients: a preliminary study. ( Benevent, D; Debord, J; Dupuis, JL; Feiss, P; Lachatre, G; Lagarde, M; Narcisse, F; Nathan, N, 1993) |
| "In the chronic renal failure group not undergoing regular hemodialysis (n = 9), unbound propofol was 0." | 1.29 | Serum protein binding of propofol in patients with renal failure or hepatic cirrhosis. ( Calvo, R; Carlos, R; Costela, JL; Jiménez, R; Suárez, E, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (29.17) | 18.2507 |
| 2000's | 9 (37.50) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 3 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, PN | 1 |
| Lu, IC | 1 |
| Huang, TW | 1 |
| Chen, PC | 1 |
| Lin, WC | 1 |
| Lu, WL | 1 |
| Tse, J | 1 |
| Cho, HB | 2 |
| Kim, MG | 2 |
| Park, SY | 2 |
| Song, S | 2 |
| Jang, YS | 1 |
| Park, S | 1 |
| Lee, HK | 1 |
| Yoo, JH | 2 |
| Chung, JW | 2 |
| Kim, SH | 2 |
| Jun, MR | 1 |
| Han, KS | 1 |
| Park, JE | 1 |
| Zhong, W | 1 |
| Zhang, Y | 1 |
| Zhang, MZ | 1 |
| Huang, XH | 1 |
| Li, Y | 1 |
| Li, R | 1 |
| Liu, QW | 1 |
| Virmani, S | 1 |
| Onuchic, A | 1 |
| El-Ali, IM | 1 |
| Trivedi, RD | 1 |
| Kumar, G | 1 |
| Gobbi, F | 1 |
| Sales, G | 1 |
| Bretto, P | 1 |
| Donadio, PP | 1 |
| Brazzi, L | 1 |
| Kocabas, S | 1 |
| Yedicocuklu, D | 1 |
| Askar, FZ | 1 |
| Igarashi, T | 1 |
| Nagata, O | 1 |
| Iwakiri, H | 1 |
| Ikeda, M | 1 |
| Ozaki, M | 1 |
| Goyal, P | 1 |
| Puri, GD | 1 |
| Pandey, CK | 1 |
| Srivastva, S | 1 |
| Sabaté Tenas, S | 1 |
| Soler Corbera, J | 1 |
| Queraltó Companyo, JM | 1 |
| Baxarias Gascón, P | 1 |
| Kakinohana, M | 1 |
| Tokumine, J | 1 |
| Kawashima, S | 1 |
| Koja, H | 1 |
| Sugahara, K | 1 |
| Tatebayashi, S | 1 |
| Imai, Y | 1 |
| Ohgi, K | 1 |
| Tamaki, S | 1 |
| Yamamoto, K | 1 |
| Takahashi, M | 1 |
| Kurehara, K | 1 |
| Furuya, H | 1 |
| Kirita, T | 1 |
| Robertson, EN | 1 |
| Driessen, JJ | 1 |
| Vogt, M | 1 |
| De Boer, H | 1 |
| Scheffer, GJ | 1 |
| Wang, YC | 1 |
| Liu, BM | 1 |
| Supernaw, RB | 1 |
| Lu, YH | 1 |
| Lee, PY | 1 |
| Honda, A | 1 |
| Arai, T | 1 |
| Akiyama, M | 1 |
| Masuda, E | 1 |
| Kobayashi, M | 1 |
| Hoka, S | 1 |
| Lee, SM | 1 |
| Kim, GH | 1 |
| Lee, JJ | 1 |
| Kim, JA | 1 |
| Choi, SJ | 1 |
| Kim, GS | 1 |
| Jung, HH | 1 |
| Nathan, N | 1 |
| Debord, J | 1 |
| Narcisse, F | 1 |
| Dupuis, JL | 1 |
| Lagarde, M | 1 |
| Benevent, D | 1 |
| Lachatre, G | 1 |
| Feiss, P | 1 |
| Costela, JL | 1 |
| Jiménez, R | 1 |
| Calvo, R | 1 |
| Suárez, E | 1 |
| Carlos, R | 1 |
| Bovianska, N | 1 |
| Kurokawa, S | 1 |
| Taga, K | 1 |
| Tobita, T | 1 |
| Kitahara, Y | 1 |
| Fukuda, S | 1 |
| Shimoji, K | 1 |
| Ickx, B | 1 |
| Cockshott, ID | 1 |
| Barvais, L | 1 |
| Byttebier, G | 1 |
| De Pauw, L | 1 |
| Vandesteene, A | 1 |
| D'Hollander, AA | 1 |
| Dahaba, AA | 1 |
| von Klobucar, F | 1 |
| Rehak, PH | 1 |
| List, WF | 1 |
| Yamauchi, M | 1 |
| Igarashi, M | 1 |
| Tsunoda, K | 1 |
| Edanaga, M | 1 |
| Suzuki, H | 1 |
| Tohdoh, Y | 1 |
| Namiki, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparative Study of Sevoflurane Sedation With TCI Propofol Sedation in Dialysis Dependent End Stage Renal Failure Patients for Transposition of Brachiocephalic Fistula Repair[NCT04839536] | Phase 4 | 36 participants (Anticipated) | Interventional | 2021-04-01 | Not yet recruiting | ||
| Evaluation of Duration of Curarisation (Surgical Efficacy) and Pharmacokinetics of Neuromuscular Block After a Single Dose of Rocuronium in Geriatric Patients (Age ≥ 80 Years ) Compared to a Younger Population (Age < 50 Years).[NCT03551652] | 28 participants (Anticipated) | Observational | 2020-05-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for propofol and Kidney Failure, Chronic
| Article | Year |
|---|---|
Application of Propofol Target-Controlled Infusion for Optimized Hemodynamic Status in ESRD Patients Receiving Arteriovenous Access Surgery: A Randomized Controlled Trial.
Topics: Anesthesia, Inhalation; Anesthetics, Intravenous; Hemodynamics; Humans; Kidney Failure, Chronic; Pai | 2022 |
The influence of propofol-based total intravenous anesthesia on postoperative outcomes in end-stage renal disease patients: A retrospective observation study.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Female; Heart Diseases; Humans; Incidence; | 2021 |
Propofol infusion for induction and maintenance of anaesthesia in patients with end-stage renal disease.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Consciousness; | 1998 |
[Cardiovascular responses during laryngeal mask airway insertion in normotensive, hypertensive and chronic renal failure patients].
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Hemodynamics; Humans; Hypertension; | 1999 |
20 other studies available for propofol and Kidney Failure, Chronic
| Article | Year |
|---|---|
Potency of propofol for inducing loss of consciousness in end-stage kidney disease patients.
Topics: Aged; Anesthesia, Epidural; Anesthesia, Intravenous; Anesthetics, Intravenous; Consciousness; Dose-R | 2021 |
Pharmacokinetics of dexmedetomidine administered to patients with end-stage renal failure and secondary hyperparathyroidism undergoing general anaesthesia.
Topics: Adult; Anesthesia, General; Case-Control Studies; Dexmedetomidine; Female; Half-Life; Humans; Hyperp | 2018 |
Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients.
Topics: Anesthetics, Intravenous; Arrhythmias, Cardiac; Electrocardiography; Heart Arrest; Humans; Hyperkale | 2016 |
Propofol as a Cause of Recurrent Pancreatitis in A Child with ESRD; A Cautionary Tale.
Topics: Anesthetics, Intravenous; Child; Female; Humans; Kidney Failure, Chronic; Pancreatitis; Propofol; Re | 2019 |
Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report.
Topics: Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Anestheti | 2016 |
The neuromuscular effects of 0.6 mg kg(-1) rocuronium in elderly and young adults with or without renal failure.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Androstanols; Anesthetics, Intravenous; Female; Humans; | 2008 |
[Evaluation of target-controlled infusion for propofol in patients with chronic renal failure undergoing living-related renal transplantation].
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Female; Humans; Infusions, Intravenous; Kidney | 2009 |
Evaluation of induction doses of propofol: comparison between endstage renal disease and normal renal function patients.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Case-Control S | 2002 |
[Predictive capability of the TCI Diprifusor system in patients with terminal chronic renal insufficiency].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Dose-Response Relationship, Dr | 2003 |
Patient-controlled sedation using propofol in eight patients with endstage renal failure.
Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Conscious Sedation; Female; Hemodynamics; Humans; Hypnot | 2004 |
[The influence of intermittent hemodialysis (HD) on bispectral index (scale) (BIS) and serum propofol concentration under postoperative intravenous sedation].
Topics: Anesthesia, General; Anesthetics, Intravenous; Gingival Neoplasms; Heart Rate; Humans; Hypnotics and | 2004 |
Pharmacodynamics of rocuronium 0.3 mg kg(-1) in adult patients with and without renal failure.
Topics: Adult; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Humans; Intubation, | 2005 |
Management of star fruit-induced neurotoxicity and seizures in a patient with chronic renal failure.
Topics: Aged, 80 and over; Anesthetics, Intravenous; Anticonvulsants; Coma; Fatal Outcome; Female; Fruit; Hu | 2006 |
Anesthetic management of a patient with a history of Batista procedure for dilated cardiomyopathy undergoing gastric surgery.
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine | 2006 |
Does propofol and alfentanil-induced sedation cause periodic apnoea in chronic renal failure patients?
Topics: Alfentanil; Anesthetics, Combined; Anesthetics, Intravenous; Apnea; Case-Control Studies; Female; Hu | 2010 |
Pharmacokinetics of propofol and its conjugates after continuous infusion in normal and in renal failure patients: a preliminary study.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Glucuronidase; Half-Life; Humans; Hydroly | 1993 |
Serum protein binding of propofol in patients with renal failure or hepatic cirrhosis.
Topics: Adult; Anesthetics, Intravenous; Bilirubin; Blood Proteins; Chromatography, High Pressure Liquid; Cr | 1996 |
[The use of atracurium besylate (Tracrium) in patients undergoing kidney transplantation].
Topics: Anesthetics, Intravenous; Atracurium; Humans; Kidney Failure, Chronic; Kidney Transplantation; Neuro | 1997 |
[Anesthetic management for pericardial fenestration in a hypertrophic cardiomyopathy (HCM) patient with massive pericardial effusion].
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Atrial Fibrillation; | 1999 |
Total intravenous anesthesia with remifentanil, propofol and cisatracurium in end-stage renal failure.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracurium; Female; Hemodynamics; Humans; | 1999 |