propofol has been researched along with Itching in 25 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the efficacy of intraoperative propofol administration to prevent pruritus induced by epidural morphine." | 9.12 | The impact of intraoperative propofol administration in the prevention of postoperative pruritus induced by epidural morphine. ( Christodoulaki, K; Crepi, E; Grigoropoulou, I; Kitsou, M; Kontogiannopoulou, S; Kostopanagiotou, G; Matiatou, S; Matsota, P; Niokou, D; Pandazi, A, 2006) |
| "The droperidol, propofol and alizapride groups had significantly lower incidences of pruritus compared with the control and promethazine groups, while the incidence of pruritus was similar among the patients assigned to the promethazine and control groups." | 9.12 | Study of the prophylactic effect of droperidol, alizapride, propofol and promethazine on spinal morphine-induced pruritus. ( Alam, RU; Costa, RC; da Cruz, AW; Dos Santos, GR; Horta, ML; Morejon, LC; Terhorst, L; Welling, LC, 2006) |
| "We compared propofol-nitrous oxide anesthesia (Group P) with isoflurane-nitrous oxide anesthesia (Group I) on the incidence of postoperative nausea, vomiting and pruritus induced by epidural morphine." | 9.09 | [Comparison of propofol and isoflurane anesthesia on postoperative nausea, vomiting and pruritus induced by epidural morphine]. ( Mashimo, T; Matsubara, Y; Matsumura, Y; Uchida, I; Yoshiya, I, 2000) |
| "The effect of subhypnotic doses of propofol on intrathecal morphine-induced pruritus was studied in a prospective, randomly allocated, double-blind controlled trial." | 9.08 | The effect of subhypnotic doses of propofol on the incidence of pruritus after intrathecal morphine for caesarean section. ( Kearns, CF; Scott, WE; Warwick, JP, 1997) |
| "The purpose of this study was to determine whether subhypnotic doses of propofol effectively relieve pruritus in women who received intrathecal morphine for postoperative analgesia after cesarean delivery." | 9.08 | Subhypnotic doses of propofol do not relieve pruritus induced by intrathecal morphine after cesarean section. ( Beilin, Y; Bernstein, HH; Zahn, J; Zenzen, WJ; Zucker-Pinchoff, B, 1998) |
| "Postoperative nausea and vomiting (PONV) following major arthroplasty with spinal anaesthesia and intrathecal morphine is reported in 45-74% of patients." | 9.08 | Nausea and vomiting after major arthroplasty with spinal anaesthesia including morphine: a randomised trial of subhypnotic propofol infusion as prophylaxis. ( Grattidge, P, 1998) |
| "We investigated the efficacy and untoward effects of low doses of propofol for intrathecal morphine-induced pruritus." | 9.08 | [The efficacy of low-dose propofol for intrathecal morphine-induced pruritus]. ( Iwasaki, H; Naganuma, R; Namiki, A; Okanuma, M; Tsuchida, H, 1998) |
| "In a prospective, randomized, double-blind clinical trial, we compared the efficacy of propofol and naloxone for the treatment of spinal-morphine-induced pruritus." | 9.07 | Epidural-morphine-induced pruritus: propofol versus naloxone. ( Borgeat, A; Rifat, K; Saiah, M; Suter, PM; Wilder-Smith, OH, 1994) |
| "This study shows that subhypnotic doses of propofol are effective for the short-term symptomatic relief of pruritus associated with liver disease." | 9.07 | Subhypnotic doses of propofol relieve pruritus associated with liver disease. ( Borgeat, A; Mentha, G; Wilder-Smith, OH, 1993) |
| "We investigated the efficacy of subhypnotic doses of propofol for spinal morphine-induced pruritus in a prospective, randomized, double-blind, placebo-controlled study." | 9.07 | Subhypnotic doses of propofol relieve pruritus induced by epidural and intrathecal morphine. ( Borgeat, A; Rifat, K; Saiah, M; Wilder-Smith, OH, 1992) |
| "Previous studies have shown that a low dose of propofol IV bolus had a beneficial effect on intrathecal morphine-induced pruritus in humans." | 7.80 | The effect of propofol on intrathecal morphine-induced pruritus and its mechanism. ( Lian, Q; Liu, X; Mei, H; ShangGuan, W; Zhang, J; Zhao, H, 2014) |
| "This is the first clinical report of morphine-induced pruritus in cats and management with low-dose propofol." | 7.79 | Neuraxial morphine induced pruritus in two cats and treatment with sub anaesthetic doses of propofol. ( Bettschart-Wolfensberger, R; Gent, T; Iff, I; Mosing, M, 2013) |
| " Although sub-hypnotic doses of propofol appear to have an antipruritic effect, replication of this finding and further investigation of optimal dosing are warranted." | 7.01 | Pharmacological agents for prevention of pruritus in women undergoing Caesarean delivery with neuraxial morphine: a systematic review and Bayesian network meta-analysis. ( Blake, L; Carvalho, B; Monks, DT; O'Carroll, J; Singh, NP; Singh, PM; Sultan, P, 2023) |
| "Propofol was recently shown to be efficient in the treatment of pruritus secondary to spinal morphine administration." | 6.67 | [Pruritus associated with liver disease: propofol, a new therapeutic approach?]. ( Borgeat, A; Mentha, G; Savioz, D; Wilder-Smith, OH, 1994) |
| "This pruritus is often intractable and resistant to conventional treatment." | 5.28 | Propofol and cholestatic pruritus. ( Borgeat, A; Huber, O; Mentha, G; Wilder-Smith, O, 1992) |
| "We examined the efficacy of intraoperative propofol administration to prevent pruritus induced by epidural morphine." | 5.12 | The impact of intraoperative propofol administration in the prevention of postoperative pruritus induced by epidural morphine. ( Christodoulaki, K; Crepi, E; Grigoropoulou, I; Kitsou, M; Kontogiannopoulou, S; Kostopanagiotou, G; Matiatou, S; Matsota, P; Niokou, D; Pandazi, A, 2006) |
| "The droperidol, propofol and alizapride groups had significantly lower incidences of pruritus compared with the control and promethazine groups, while the incidence of pruritus was similar among the patients assigned to the promethazine and control groups." | 5.12 | Study of the prophylactic effect of droperidol, alizapride, propofol and promethazine on spinal morphine-induced pruritus. ( Alam, RU; Costa, RC; da Cruz, AW; Dos Santos, GR; Horta, ML; Morejon, LC; Terhorst, L; Welling, LC, 2006) |
| " Inadequate analgesia was treated with IV propofol, and the epidural was activated for a pain score greater than 6 on a 10-point verbal analog pain scale." | 5.09 | Determination of the effective therapeutic dose of intrathecal sufentanil for extracorporeal shock wave lithotripsy. ( Faerber, GJ; Golembiewski, JA; Green, CR; Lau, WC; Tait, AR, 1999) |
| "We compared propofol-nitrous oxide anesthesia (Group P) with isoflurane-nitrous oxide anesthesia (Group I) on the incidence of postoperative nausea, vomiting and pruritus induced by epidural morphine." | 5.09 | [Comparison of propofol and isoflurane anesthesia on postoperative nausea, vomiting and pruritus induced by epidural morphine]. ( Mashimo, T; Matsubara, Y; Matsumura, Y; Uchida, I; Yoshiya, I, 2000) |
| "The effect of subhypnotic doses of propofol on intrathecal morphine-induced pruritus was studied in a prospective, randomly allocated, double-blind controlled trial." | 5.08 | The effect of subhypnotic doses of propofol on the incidence of pruritus after intrathecal morphine for caesarean section. ( Kearns, CF; Scott, WE; Warwick, JP, 1997) |
| "The purpose of this study was to determine whether subhypnotic doses of propofol effectively relieve pruritus in women who received intrathecal morphine for postoperative analgesia after cesarean delivery." | 5.08 | Subhypnotic doses of propofol do not relieve pruritus induced by intrathecal morphine after cesarean section. ( Beilin, Y; Bernstein, HH; Zahn, J; Zenzen, WJ; Zucker-Pinchoff, B, 1998) |
| "Postoperative nausea and vomiting (PONV) following major arthroplasty with spinal anaesthesia and intrathecal morphine is reported in 45-74% of patients." | 5.08 | Nausea and vomiting after major arthroplasty with spinal anaesthesia including morphine: a randomised trial of subhypnotic propofol infusion as prophylaxis. ( Grattidge, P, 1998) |
| "We investigated the efficacy and untoward effects of low doses of propofol for intrathecal morphine-induced pruritus." | 5.08 | [The efficacy of low-dose propofol for intrathecal morphine-induced pruritus]. ( Iwasaki, H; Naganuma, R; Namiki, A; Okanuma, M; Tsuchida, H, 1998) |
| "In a prospective, randomized, double-blind clinical trial, we compared the efficacy of propofol and naloxone for the treatment of spinal-morphine-induced pruritus." | 5.07 | Epidural-morphine-induced pruritus: propofol versus naloxone. ( Borgeat, A; Rifat, K; Saiah, M; Suter, PM; Wilder-Smith, OH, 1994) |
| "This study shows that subhypnotic doses of propofol are effective for the short-term symptomatic relief of pruritus associated with liver disease." | 5.07 | Subhypnotic doses of propofol relieve pruritus associated with liver disease. ( Borgeat, A; Mentha, G; Wilder-Smith, OH, 1993) |
| "We investigated the efficacy of subhypnotic doses of propofol for spinal morphine-induced pruritus in a prospective, randomized, double-blind, placebo-controlled study." | 5.07 | Subhypnotic doses of propofol relieve pruritus induced by epidural and intrathecal morphine. ( Borgeat, A; Rifat, K; Saiah, M; Wilder-Smith, OH, 1992) |
| "Previous studies have shown that a low dose of propofol IV bolus had a beneficial effect on intrathecal morphine-induced pruritus in humans." | 3.80 | The effect of propofol on intrathecal morphine-induced pruritus and its mechanism. ( Lian, Q; Liu, X; Mei, H; ShangGuan, W; Zhang, J; Zhao, H, 2014) |
| "This is the first clinical report of morphine-induced pruritus in cats and management with low-dose propofol." | 3.79 | Neuraxial morphine induced pruritus in two cats and treatment with sub anaesthetic doses of propofol. ( Bettschart-Wolfensberger, R; Gent, T; Iff, I; Mosing, M, 2013) |
| " Although sub-hypnotic doses of propofol appear to have an antipruritic effect, replication of this finding and further investigation of optimal dosing are warranted." | 3.01 | Pharmacological agents for prevention of pruritus in women undergoing Caesarean delivery with neuraxial morphine: a systematic review and Bayesian network meta-analysis. ( Blake, L; Carvalho, B; Monks, DT; O'Carroll, J; Singh, NP; Singh, PM; Sultan, P, 2023) |
| "Propofol was recently shown to be efficient in the treatment of pruritus secondary to spinal morphine administration." | 2.67 | [Pruritus associated with liver disease: propofol, a new therapeutic approach?]. ( Borgeat, A; Mentha, G; Savioz, D; Wilder-Smith, OH, 1994) |
| "The phenomenon of itching has received surprisingly little scientific scrutiny despite its commonality--hence its designation as a kind of neglected, "orphan symptom." | 2.43 | Update for nurse anesthetists--pt 4. Itching, the "little" big problem as an orphan symptom. ( Biddle, C; Toomey, M, 2006) |
| "This pruritus is often intractable and resistant to conventional treatment." | 1.28 | Propofol and cholestatic pruritus. ( Borgeat, A; Huber, O; Mentha, G; Wilder-Smith, O, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (64.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Singh, PM | 1 |
| Sultan, P | 1 |
| O'Carroll, J | 1 |
| Blake, L | 1 |
| Carvalho, B | 1 |
| Singh, NP | 1 |
| Monks, DT | 1 |
| Kampo, S | 1 |
| Afful, AP | 1 |
| Mohammed, S | 1 |
| Ntim, M | 1 |
| Buunaaim, ADB | 1 |
| Anabah, TW | 1 |
| Gent, T | 1 |
| Iff, I | 1 |
| Bettschart-Wolfensberger, R | 1 |
| Mosing, M | 1 |
| Liu, X | 1 |
| Zhang, J | 1 |
| Zhao, H | 1 |
| Mei, H | 1 |
| Lian, Q | 1 |
| ShangGuan, W | 1 |
| Kostopanagiotou, G | 1 |
| Pandazi, A | 1 |
| Matiatou, S | 1 |
| Kontogiannopoulou, S | 1 |
| Matsota, P | 1 |
| Niokou, D | 1 |
| Kitsou, M | 1 |
| Crepi, E | 1 |
| Christodoulaki, K | 1 |
| Grigoropoulou, I | 1 |
| Horta, ML | 1 |
| Morejon, LC | 1 |
| da Cruz, AW | 1 |
| Dos Santos, GR | 1 |
| Welling, LC | 1 |
| Terhorst, L | 1 |
| Costa, RC | 1 |
| Alam, RU | 1 |
| Toomey, M | 1 |
| Biddle, C | 1 |
| Nightingale, C | 1 |
| Borgeat, A | 7 |
| Savioz, D | 2 |
| Mentha, G | 4 |
| Giostra, E | 1 |
| Suter, PM | 2 |
| Törn, K | 1 |
| Tuominen, M | 1 |
| Tarkkila, P | 1 |
| Lindgren, L | 1 |
| Wilder-Smith, OH | 4 |
| Saiah, M | 2 |
| Rifat, K | 2 |
| Riley, RH | 1 |
| Khandelwal, M | 1 |
| Malet, PF | 1 |
| Warwick, JP | 1 |
| Kearns, CF | 1 |
| Scott, WE | 1 |
| Beilin, Y | 1 |
| Bernstein, HH | 1 |
| Zucker-Pinchoff, B | 1 |
| Zahn, J | 1 |
| Zenzen, WJ | 1 |
| Grattidge, P | 1 |
| Naganuma, R | 1 |
| Tsuchida, H | 1 |
| Okanuma, M | 1 |
| Iwasaki, H | 1 |
| Namiki, A | 1 |
| Lau, WC | 1 |
| Green, CR | 1 |
| Faerber, GJ | 1 |
| Tait, AR | 1 |
| Golembiewski, JA | 1 |
| Matsumura, Y | 1 |
| Matsubara, Y | 1 |
| Uchida, I | 1 |
| Mashimo, T | 1 |
| Yoshiya, I | 1 |
| Wilder-Smith, O | 2 |
| Huber, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Elective Cesarean Section Under Spinal Anesthesia.[NCT05071794] | Phase 4 | 60 participants (Actual) | Interventional | 2021-05-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for propofol and Itching
| Article | Year |
|---|---|
Pharmacological agents for prevention of pruritus in women undergoing Caesarean delivery with neuraxial morphine: a systematic review and Bayesian network meta-analysis.
Topics: Adult; Analgesics, Opioid; Bayes Theorem; Cesarean Section; Female; Humans; Morphine; Network Meta-A | 2023 |
Update for nurse anesthetists--pt 4. Itching, the "little" big problem as an orphan symptom.
Topics: Acetylcholine; Analgesics, Opioid; Anesthesia; Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; | 2006 |
Pruritus associated with cholestasis. A review of pathogenesis and management.
Topics: Androgens; Antipruritics; Bile Acids and Salts; Cholestasis; Cholestyramine Resin; Female; Humans; N | 1994 |
14 trials available for propofol and Itching
| Article | Year |
|---|---|
Sub-hypnotic dose of propofol as antiemetic prophylaxis attenuates intrathecal morphine-induced postoperative nausea and vomiting, and pruritus in parturient undergoing cesarean section - a randomized control trial.
Topics: Adult; Analgesics, Opioid; Antiemetics; Cesarean Section; Dose-Response Relationship, Drug; Double-B | 2019 |
The impact of intraoperative propofol administration in the prevention of postoperative pruritus induced by epidural morphine.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, | 2006 |
Study of the prophylactic effect of droperidol, alizapride, propofol and promethazine on spinal morphine-induced pruritus.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Antipruritics; C | 2006 |
Effects of sub-hypnotic doses of propofol on the side effects of intrathecal morphine.
Topics: Aged; Aged, 80 and over; Double-Blind Method; Humans; Infusions, Intravenous; Middle Aged; Morphine; | 1994 |
[Pruritus associated with liver disease: propofol, a new therapeutic approach?].
Topics: Adult; Aged; Double-Blind Method; Fat Emulsions, Intravenous; Female; Humans; Liver Diseases; Male; | 1994 |
Epidural-morphine-induced pruritus: propofol versus naloxone.
Topics: Adult; Aged; Analgesia, Epidural; Double-Blind Method; Elective Surgical Procedures; Humans; Middle | 1994 |
Subhypnotic doses of propofol relieve pruritus associated with liver disease.
Topics: Adult; Aged; Cholestasis, Intrahepatic; Double-Blind Method; Humans; Hypnotics and Sedatives; Middle | 1993 |
The effect of subhypnotic doses of propofol on the incidence of pruritus after intrathecal morphine for caesarean section.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Double-Bli | 1997 |
Subhypnotic doses of propofol do not relieve pruritus induced by intrathecal morphine after cesarean section.
Topics: Adult; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Propofol; Prospective Studie | 1998 |
Nausea and vomiting after major arthroplasty with spinal anaesthesia including morphine: a randomised trial of subhypnotic propofol infusion as prophylaxis.
Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Antiemetics; Arthroplasty, Replace | 1998 |
[The efficacy of low-dose propofol for intrathecal morphine-induced pruritus].
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Spinal; Female; Genital Diseases, Female; Humans; Hypno | 1998 |
Determination of the effective therapeutic dose of intrathecal sufentanil for extracorporeal shock wave lithotripsy.
Topics: Adolescent; Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, I | 1999 |
[Comparison of propofol and isoflurane anesthesia on postoperative nausea, vomiting and pruritus induced by epidural morphine].
Topics: Aged; Analgesia, Epidural; Anesthesia, General; Female; Humans; Isoflurane; Male; Middle Aged; Morph | 2000 |
Subhypnotic doses of propofol relieve pruritus induced by epidural and intrathecal morphine.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Injections, Epidural; Injections, Spinal; Male; Mi | 1992 |
8 other studies available for propofol and Itching
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Neuraxial morphine induced pruritus in two cats and treatment with sub anaesthetic doses of propofol.
Topics: Analgesics, Opioid; Animals; Cat Diseases; Cats; Dose-Response Relationship, Drug; Female; Hypnotics | 2013 |
The effect of propofol on intrathecal morphine-induced pruritus and its mechanism.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Animals; Catheterization, Central Venous; Dose-Respons | 2014 |
A new treatment for epidural opioid induced pruritus in parturients.
Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Drug Eruptions; Female; Humans; Pre | 1995 |
Intractable cholestatic pruritus after liver transplantation--management with propofol.
Topics: Adult; Cholestasis; Humans; Infusions, Intravenous; Liver Transplantation; Male; Middle Aged; Propof | 1994 |
Propofol i.v. for intrathecal pethidine-induced pruritus.
Topics: Adult; Anesthesia, Spinal; Humans; Injections, Intravenous; Male; Meperidine; Propofol; Pruritus | 1993 |
Propofol and cholestatic pruritus.
Topics: Aged; Cholestasis; Drug Administration Schedule; Female; Humans; Male; Pancreatic Neoplasms; Propofo | 1992 |
Central pruritus: case report.
Topics: Aged; Aged, 80 and over; Female; Humans; Propofol; Pruritus | 1991 |