propofol has been researched along with Invasiveness, Neoplasm in 42 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol suppresses cell proliferation, migration and invasion of osteosarcoma cells through FOXO1/TUSC7 axis by regulating AKT/GSK3β signalling." | 8.02 | Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7. ( Huang, X; Liu, J; Xie, H, 2021) |
| "Sevoflurane, but not propofol, at clinically relevant concentrations and durations, increased survival of breast cancer cells in vitro but had no effect on cell proliferation, migration or TRPV1 expression." | 7.96 | Sevoflurane modulates breast cancer cell survival via modulation of intracellular calcium homeostasis. ( Deng, X; Gouda, D; Liang, G; Vipani, M; Wang, B; Wei, H, 2020) |
| "BACKGROUND This study was done to verify whether propofol could inhibit esophageal squamous cell carcinoma (ESCC) cell line EC9706 cell migration and invasion by targeting SOX4." | 7.85 | Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4). ( Ji, P; Li, JJ; Zhou, CL, 2017) |
| "To explore the effect of propofol on H19 expression, migration and invasion of human breast cancer MDA-MB-231 cells in vitro." | 7.83 | [Propofol suppresses migration and invasion of breast cancer MDA-MB-231 cells by down-regulating H19]. ( Bai, JJ; Guo, PP; Lin, CS; Wang, W; Ye, HJ, 2016) |
| "Propofol decreases hepatocellular carcinoma cell invasiveness, which is partly due to the down-regulation of MMP-9 expression by miR-199a." | 7.79 | Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. ( Feng, ZY; Wu, GQ; Zhang, D; Zhang, J; Zhu, SM, 2013) |
| "However, the effects of propofol in bladder cancer (BC) are yet to be fully elucidated." | 5.62 | Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR‑145‑5p/TOP2A axis. ( Chen, Y; Du, Y; Pan, H; Shu, J; Zhang, H; Zhang, X; Zhu, S, 2021) |
| "Glioma is a common primary intracranial tumor, with high infiltration and aggression." | 5.62 | Propofol Represses Cell Growth and Metastasis by Modulating the Circular RNA Non-SMC Condensin I Complex Subunit G/MicroRNA-200a-3p/RAB5A Axis in Glioma. ( Chen, H; Tian, C; Zhang, L; Zheng, D, 2021) |
| "Propofol is a commonly used drug for the induction and maintenance of anesthesia." | 5.56 | Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. ( Feng, Y; Jin, Y; Liu, J; Song, F, 2020) |
| "Propofol treatment significantly inhibited cell proliferation, migration and invasion, and reduced the releasing of EMT." | 5.51 | Propofol inhibits proliferation and metastasis by up-regulation of miR-495 in JEG-3 choriocarcinoma cells. ( Sun, H; Wang, Y; Zhang, W, 2019) |
| "Propofol is an intravenous anesthetic widely used in clinical surgeries, such as tumor resection." | 5.51 | Propofol suppresses proliferation, invasion, and migration of human melanoma cells via regulating microRNA-137 and fibroblast growth factor 9. ( Guo, Q; Li, R; Ma, M; Wang, X; Yu, H; Zhou, Z, 2019) |
| "Propofol is a known anesthetic agent, widely used for short-term anesthesia and for longer-term sedation." | 5.38 | Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells. ( Chiou, SM; Chung, JG; Hsia, TC; Lu, CC; Wu, KC; Wu, RS; Yang, JS; Yang, ST, 2012) |
| "Propofol suppresses cell proliferation, migration and invasion of osteosarcoma cells through FOXO1/TUSC7 axis by regulating AKT/GSK3β signalling." | 4.02 | Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7. ( Huang, X; Liu, J; Xie, H, 2021) |
| "Sevoflurane, but not propofol, at clinically relevant concentrations and durations, increased survival of breast cancer cells in vitro but had no effect on cell proliferation, migration or TRPV1 expression." | 3.96 | Sevoflurane modulates breast cancer cell survival via modulation of intracellular calcium homeostasis. ( Deng, X; Gouda, D; Liang, G; Vipani, M; Wang, B; Wei, H, 2020) |
| "BACKGROUND This study was done to verify whether propofol could inhibit esophageal squamous cell carcinoma (ESCC) cell line EC9706 cell migration and invasion by targeting SOX4." | 3.85 | Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4). ( Ji, P; Li, JJ; Zhou, CL, 2017) |
| "To explore the effect of propofol on H19 expression, migration and invasion of human breast cancer MDA-MB-231 cells in vitro." | 3.83 | [Propofol suppresses migration and invasion of breast cancer MDA-MB-231 cells by down-regulating H19]. ( Bai, JJ; Guo, PP; Lin, CS; Wang, W; Ye, HJ, 2016) |
| "Propofol decreases hepatocellular carcinoma cell invasiveness, which is partly due to the down-regulation of MMP-9 expression by miR-199a." | 3.79 | Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. ( Feng, ZY; Wu, GQ; Zhang, D; Zhang, J; Zhu, SM, 2013) |
| "Propofol is a commonly used anesthetic with controversial effects on cancer cells." | 1.62 | Propofol mediates pancreatic cancer cell activity through the repression of ADAM8 via SP1. ( Ben-David, Y; Gao, Y; Sample, KM; Wang, C; Yu, X; Zhou, Y, 2021) |
| "Propofol inhibited ovarian cancer cell proliferation, glycolysis metabolism, migration and invasion, which were partly recovered by circ_MUC16 overexpression." | 1.62 | Circ_MUC16 attenuates the effects of Propofol to promote the aggressive behaviors of ovarian cancer by mediating the miR-1182/S100B signaling pathway. ( Guo, Y; Hou, J; Wang, D; Yang, H; Yang, J; Zhang, G; Zhang, Y, 2021) |
| "However, the effects of propofol in bladder cancer (BC) are yet to be fully elucidated." | 1.62 | Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR‑145‑5p/TOP2A axis. ( Chen, Y; Du, Y; Pan, H; Shu, J; Zhang, H; Zhang, X; Zhu, S, 2021) |
| "Glioma is a common primary intracranial tumor, with high infiltration and aggression." | 1.62 | Propofol Represses Cell Growth and Metastasis by Modulating the Circular RNA Non-SMC Condensin I Complex Subunit G/MicroRNA-200a-3p/RAB5A Axis in Glioma. ( Chen, H; Tian, C; Zhang, L; Zheng, D, 2021) |
| "Propofol treatment significantly promoted cell migration and invasion of OSCC." | 1.56 | Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression. ( Jiang, H; Li, C; Li, W; Peng, J; Wang, H; Xia, M, 2020) |
| "Human colon cancer cell lines were cultured and exposed with 8 μg/mL propofol." | 1.56 | Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF-1 and suppressing Wnt pathway. ( Li, CS; Lu, XH; Zhang, YF; Zhou, Y, 2020) |
| "BACKGROUND Gastric cancer (GC) is a life-threating malignancy worldwide." | 1.56 | Propofol Reduces Epithelial to Mesenchymal Transition, Invasion and Migration of Gastric Cancer Cells through the MicroRNA-195-5p/Snail Axis. ( Chen, H; Fu, M; Liu, F; Qiu, F; Wang, H, 2020) |
| "Propofol has been reported to be related to the migration, invasion, and epithelial-mesenchymal transition (EMT) of esophageal cancer (EC) cells." | 1.56 | Propofol suppresses hypoxia-induced esophageal cancer cell migration, invasion, and EMT through regulating lncRNA TMPO-AS1/miR-498 axis. ( Gao, M; Guo, R; Lu, X; Luo, S; Xu, G, 2020) |
| "Propofol is a commonly used drug for the induction and maintenance of anesthesia." | 1.56 | Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. ( Feng, Y; Jin, Y; Liu, J; Song, F, 2020) |
| "Propofol treatment significantly inhibited cell proliferation, migration and invasion, and reduced the releasing of EMT." | 1.51 | Propofol inhibits proliferation and metastasis by up-regulation of miR-495 in JEG-3 choriocarcinoma cells. ( Sun, H; Wang, Y; Zhang, W, 2019) |
| "Propofol is an intravenous anesthetic widely used in clinical surgeries, such as tumor resection." | 1.51 | Propofol suppresses proliferation, invasion, and migration of human melanoma cells via regulating microRNA-137 and fibroblast growth factor 9. ( Guo, Q; Li, R; Ma, M; Wang, X; Yu, H; Zhou, Z, 2019) |
| "Propofol treatment suppressed MKN45 cell proliferation, migration and invasion, but promoted cell apoptosis." | 1.48 | Propofol inhibits proliferation, migration and invasion of gastric cancer cells by up-regulating microRNA-195. ( Song, B; Wang, Y; Zhang, W; Zheng, Y; Zhu, Z, 2018) |
| "Propofol has been widely used in lung cancer resections." | 1.48 | Propofol Inhibits Lung Cancer A549 Cell Growth and Epithelial-Mesenchymal Transition Process by Upregulation of MicroRNA-1284. ( Liu, N; Liu, WZ, 2018) |
| "However, the roles of propofol in endometrial cancer (EC) remain unclear." | 1.48 | Propofol inhibits proliferation, migration, and invasion but promotes apoptosis by regulation of Sox4 in endometrial cancer cells. ( Du, Q; Liu, J; Wang, S; Wei, M; Zhang, X; Zhu, H, 2018) |
| "The LoVo colon cancer cells were cultured with patient serum from both groups and the effects on proliferation, invasion and apoptosis were measured." | 1.43 | Effects of anaesthesia on proliferation, invasion and apoptosis of LoVo colon cancer cells in vitro. ( Chen, WK; Cheng, Q; Li, SY; Miao, CH; Ren, Y; Wang, SL; Xu, YJ, 2016) |
| "Propofol is a commonly used intravenous anesthetic." | 1.42 | Propofol suppresses proliferation and invasion of pancreatic cancer cells by upregulating microRNA-133a expression. ( Dong, TL; Gong, HY; Liu, DJ; Wang, ZT; Zheng, F, 2015) |
| "Treatment with propofol induced apoptosis and increased paclitaxel killing of all paclitaxel-sensitive and -resistant ovarian cancer cells followed by significant decrease in the Slug levels." | 1.39 | Propofol inhibits invasion and enhances paclitaxel- induced apoptosis in ovarian cancer cells through the suppression of the transcription factor slug. ( Chen, J; Du, QH; Mu, LH; Niu, XH; Wang, P; Zhang, MY, 2013) |
| "Propofol is a common clinical anesthesia agent which is now widely used in relieving pain of patients with chronic cancer as an adjuvant therapy." | 1.38 | Propofol reduces MMPs expression by inhibiting NF-κB activity in human MDA-MB-231 cells. ( Han, Y; Jiang, Z; Li, Q; Wang, Q; Zhang, L, 2012) |
| "Propofol is a known anesthetic agent, widely used for short-term anesthesia and for longer-term sedation." | 1.38 | Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells. ( Chiou, SM; Chung, JG; Hsia, TC; Lu, CC; Wu, KC; Wu, RS; Yang, JS; Yang, ST, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (4.76) | 29.6817 |
| 2010's | 25 (59.52) | 24.3611 |
| 2020's | 15 (35.71) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, Y | 2 |
| Zhou, Y | 2 |
| Wang, C | 1 |
| Sample, KM | 1 |
| Yu, X | 3 |
| Ben-David, Y | 1 |
| Yang, H | 2 |
| Guo, Y | 1 |
| Zhang, Y | 2 |
| Wang, D | 2 |
| Zhang, G | 1 |
| Hou, J | 1 |
| Yang, J | 2 |
| Li, C | 1 |
| Xia, M | 1 |
| Wang, H | 2 |
| Li, W | 2 |
| Peng, J | 1 |
| Jiang, H | 1 |
| Zhang, YF | 1 |
| Li, CS | 1 |
| Lu, XH | 1 |
| Li, F | 2 |
| Chen, W | 1 |
| Shi, J | 1 |
| Wang, X | 2 |
| Zhang, F | 2 |
| Liu, F | 1 |
| Qiu, F | 1 |
| Fu, M | 1 |
| Chen, H | 2 |
| Gao, M | 1 |
| Guo, R | 1 |
| Lu, X | 1 |
| Xu, G | 1 |
| Luo, S | 1 |
| Song, F | 1 |
| Liu, J | 3 |
| Feng, Y | 1 |
| Jin, Y | 1 |
| Zhao, H | 2 |
| Wei, H | 2 |
| He, J | 1 |
| Wang, Y | 3 |
| Ai, Y | 1 |
| Deng, X | 1 |
| Vipani, M | 1 |
| Liang, G | 1 |
| Gouda, D | 1 |
| Wang, B | 2 |
| Huang, X | 2 |
| Xie, H | 1 |
| Du, Y | 1 |
| Zhang, X | 3 |
| Zhang, H | 1 |
| Chen, Y | 1 |
| Zhu, S | 1 |
| Shu, J | 1 |
| Pan, H | 1 |
| Zhang, L | 3 |
| Tian, C | 1 |
| Zheng, D | 1 |
| Hu, C | 1 |
| Iwasaki, M | 1 |
| Liu, Z | 1 |
| Li, X | 1 |
| Lin, H | 1 |
| Li, J | 1 |
| Li, JV | 1 |
| Lian, Q | 1 |
| Ma, D | 2 |
| Yang, N | 1 |
| Liang, Y | 1 |
| Yang, P | 1 |
| Ji, F | 1 |
| Liu, WZ | 1 |
| Liu, N | 1 |
| Du, Q | 1 |
| Zhu, H | 1 |
| Wei, M | 1 |
| Wang, S | 1 |
| Zhang, W | 2 |
| Zhu, Z | 1 |
| Zheng, Y | 1 |
| Song, B | 1 |
| Sun, H | 2 |
| Gao, D | 1 |
| Yu, H | 1 |
| Ma, M | 1 |
| Zhou, Z | 1 |
| Li, R | 1 |
| Guo, Q | 1 |
| Zhang, J | 1 |
| Zhang, D | 1 |
| Wu, GQ | 1 |
| Feng, ZY | 1 |
| Zhu, SM | 1 |
| Wang, P | 1 |
| Chen, J | 1 |
| Mu, LH | 1 |
| Du, QH | 2 |
| Niu, XH | 1 |
| Zhang, MY | 2 |
| Xu, YB | 1 |
| Yun, P | 1 |
| He, CY | 1 |
| Ye, Z | 1 |
| Jingzhong, L | 1 |
| Yangbo, L | 1 |
| Lei, C | 1 |
| Jiandong, Y | 1 |
| Huang, H | 1 |
| Benzonana, LL | 1 |
| Watts, HR | 1 |
| Perry, NJ | 1 |
| Bevan, C | 1 |
| Brown, R | 1 |
| Wang, ZT | 2 |
| Gong, HY | 2 |
| Zheng, F | 2 |
| Liu, DJ | 2 |
| Dong, TL | 1 |
| Yue, XQ | 1 |
| Xu, YJ | 1 |
| Li, SY | 1 |
| Cheng, Q | 1 |
| Chen, WK | 1 |
| Wang, SL | 1 |
| Ren, Y | 1 |
| Miao, CH | 1 |
| Bai, JJ | 2 |
| Lin, CS | 2 |
| Ye, HJ | 2 |
| Guo, PP | 2 |
| Wang, W | 2 |
| Teng, Y | 1 |
| Ma, J | 1 |
| Zhou, CL | 1 |
| Li, JJ | 1 |
| Ji, P | 1 |
| Miao, Y | 1 |
| Wan, H | 1 |
| Chen, L | 1 |
| Wang, F | 1 |
| Zhang, LM | 1 |
| Zhang, MX | 1 |
| Wang, N | 2 |
| Duan, XY | 1 |
| Zhou, SN | 1 |
| Wang, JS | 1 |
| Jing, GX | 1 |
| Li, Q | 1 |
| Han, Y | 1 |
| Jiang, Z | 1 |
| Wang, Q | 1 |
| Zhou, S | 1 |
| Ye, W | 1 |
| Jing, G | 1 |
| Zhang, M | 1 |
| Wu, KC | 1 |
| Yang, ST | 1 |
| Hsia, TC | 1 |
| Yang, JS | 1 |
| Chiou, SM | 1 |
| Lu, CC | 1 |
| Wu, RS | 1 |
| Chung, JG | 1 |
| Mammoto, T | 2 |
| Mukai, M | 1 |
| Mammoto, A | 1 |
| Yamanaka, Y | 1 |
| Hayashi, Y | 1 |
| Mashimo, T | 1 |
| Kishi, Y | 2 |
| Nakamura, H | 1 |
| Baba, M | 1 |
| Nakagawa, M | 1 |
| Kuri, M | 1 |
| Taniguchi, H | 1 |
| Kanbara, N | 1 |
| Sakai, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Active, not recruiting | |||
| Anesthesia and Immunological and Oxidative Stress in Relation to Abdominal Cancer Surgery[NCT03974984] | 0 participants (Actual) | Observational | 2020-06-04 | Withdrawn (stopped due to Not feasable due to logistics) | |||
| A Prospective, Randomized, Controlled Trial to Compare the Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serumserum Biomarkers and on PBMCs in Patients Undergoing Breast Cancer Resection Surgery[NCT03005860] | 0 participants (Actual) | Interventional | 2017-01-01 | Withdrawn (stopped due to Funding could not be arranged, so the study was prematurely terminated) | |||
| A Randomized, Open-label Study to Compare Propofol Anesthesia With Sevoflurane Anesthesia in Terms of Overall Survival in Patients With Surgical Intervention for Either Breast-, Colon- or Rectal Cancer[NCT01975064] | Phase 4 | 5,774 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
42 other studies available for propofol and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Propofol mediates pancreatic cancer cell activity through the repression of ADAM8 via SP1.
Topics: ADAM Proteins; Anesthetics, Intravenous; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Prolifera | 2021 |
Circ_MUC16 attenuates the effects of Propofol to promote the aggressive behaviors of ovarian cancer by mediating the miR-1182/S100B signaling pathway.
Topics: Animals; CA-125 Antigen; Cell Line, Tumor; Female; Hypnotics and Sedatives; Membrane Proteins; Mice; | 2021 |
Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Movement; Cell Proliferation; Gene Expression Regulation, | 2020 |
Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF-1 and suppressing Wnt pathway.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Colonic N | 2020 |
Propofol Inhibits Cell Proliferation, Migration, and Invasion via mir-410-3p/Transforming Growth Factor-β Receptor Type 2 (TGFBR2) Axis in Glioma.
Topics: 3' Untranslated Regions; Cell Line, Tumor; Cell Movement; Cell Proliferation; China; Gene Expression | 2020 |
Propofol affects the growth and metastasis of pancreatic cancer via ADAM8.
Topics: ADAM Proteins; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Prol | 2020 |
Propofol Reduces Epithelial to Mesenchymal Transition, Invasion and Migration of Gastric Cancer Cells through the MicroRNA-195-5p/Snail Axis.
Topics: Anesthetics; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Dose-Response Relation | 2020 |
Propofol suppresses hypoxia-induced esophageal cancer cell migration, invasion, and EMT through regulating lncRNA TMPO-AS1/miR-498 axis.
Topics: Cell Movement; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Female; Humans; Hypnotics an | 2020 |
Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458.
Topics: Anesthetics, Intravenous; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Prol | 2020 |
Propofol disrupts cell carcinogenesis and aerobic glycolysis by regulating circTADA2A/miR-455-3p/FOXM1 axis in lung cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Female; Forkhead Box | 2020 |
Sevoflurane modulates breast cancer cell survival via modulation of intracellular calcium homeostasis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Breast Neoplasms; Calcium; Cell Survival; Female; | 2020 |
Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7.
Topics: Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Forkhead Box Protein O1; Glycog | 2021 |
Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR‑145‑5p/TOP2A axis.
Topics: Adult; Aged; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; China; DNA Topoisomerases | 2021 |
Propofol Represses Cell Growth and Metastasis by Modulating the Circular RNA Non-SMC Condensin I Complex Subunit G/MicroRNA-200a-3p/RAB5A Axis in Glioma.
Topics: Adult; Anesthetics, Intravenous; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Movement; Cel | 2021 |
Lung but not brain cancer cell malignancy inhibited by commonly used anesthetic propofol during surgery: Implication of reducing cancer recurrence risk.
Topics: A549 Cells; Anesthetics, Intravenous; Antineoplastic Agents; Brain Neoplasms; Cell Movement; Cell Pr | 2021 |
Propofol suppresses LPS-induced nuclear accumulation of HIF-1α and tumor aggressiveness in non-small cell lung cancer.
Topics: A549 Cells; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; | 2017 |
Propofol Inhibits Lung Cancer A549 Cell Growth and Epithelial-Mesenchymal Transition Process by Upregulation of MicroRNA-1284.
Topics: A549 Cells; Cell Movement; Cell Proliferation; Cell Survival; Epithelial-Mesenchymal Transition; For | 2018 |
Propofol inhibits proliferation, migration, and invasion but promotes apoptosis by regulation of Sox4 in endometrial cancer cells.
Topics: Animals; Apoptosis; beta Catenin; Cell Line, Tumor; Cell Movement; Cell Survival; Endometrial Neopla | 2018 |
Propofol inhibits proliferation, migration and invasion of gastric cancer cells by up-regulating microRNA-195.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplast | 2018 |
Propofol suppresses growth, migration and invasion of A549 cells by down-regulation of miR-372.
Topics: A549 Cells; Cell Movement; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplast | 2018 |
Propofol inhibits pancreatic cancer proliferation and metastasis by up-regulating miR-328 and down-regulating ADAM8.
Topics: ADAM Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Down-Regulation; | 2019 |
Propofol inhibits proliferation and metastasis by up-regulation of miR-495 in JEG-3 choriocarcinoma cells.
Topics: Bile Duct Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Choriocarci | 2019 |
Propofol suppresses proliferation, invasion, and migration of human melanoma cells via regulating microRNA-137 and fibroblast growth factor 9.
Topics: Anesthetics, Intravenous; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation | 2019 |
Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression.
Topics: Anesthetics, Intravenous; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Dose-Response Rel | 2013 |
Propofol inhibits invasion and enhances paclitaxel- induced apoptosis in ovarian cancer cells through the suppression of the transcription factor slug.
Topics: Anesthetics, Intravenous; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line | 2013 |
Propofol inhibits invasion and enhances paclitaxel- induced apoptosis in ovarian cancer cells through the suppression of the transcription factor slug.
Topics: Anesthetics, Intravenous; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line | 2013 |
Propofol inhibits invasion and enhances paclitaxel- induced apoptosis in ovarian cancer cells through the suppression of the transcription factor slug.
Topics: Anesthetics, Intravenous; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line | 2013 |
Propofol inhibits invasion and enhances paclitaxel- induced apoptosis in ovarian cancer cells through the suppression of the transcription factor slug.
Topics: Anesthetics, Intravenous; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line | 2013 |
Propofol suppresses proliferation, invasion and angiogenesis by down-regulating ERK-VEGF/MMP-9 signaling in Eca-109 esophageal squamous cell carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Esophageal Neoplasm | 2013 |
Propofol inhibits proliferation and invasion of osteosarcoma cells by regulation of microRNA-143 expression.
Topics: Anesthetics, Intravenous; Apoptosis; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell S | 2013 |
Prostate cancer cell malignancy via modulation of HIF-1α pathway with isoflurane and propofol alone and in combination.
Topics: Anesthetics, Inhalation; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; | 2014 |
Prostate cancer cell malignancy via modulation of HIF-1α pathway with isoflurane and propofol alone and in combination.
Topics: Anesthetics, Inhalation; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; | 2014 |
Prostate cancer cell malignancy via modulation of HIF-1α pathway with isoflurane and propofol alone and in combination.
Topics: Anesthetics, Inhalation; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; | 2014 |
Prostate cancer cell malignancy via modulation of HIF-1α pathway with isoflurane and propofol alone and in combination.
Topics: Anesthetics, Inhalation; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; | 2014 |
Propofol suppresses proliferation and invasion of pancreatic cancer cells by upregulating microRNA-133a expression.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Mic | 2015 |
Propofol suppresses proliferation and invasion of gastric cancer cells via downregulation of microRNA-221 expression.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neopla | 2015 |
Effects of anaesthesia on proliferation, invasion and apoptosis of LoVo colon cancer cells in vitro.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia; Anesthesia, Epidural; Anesthetics, Inhalation; Anestheti | 2016 |
[Propofol suppresses migration and invasion of breast cancer MDA-MB-231 cells by down-regulating H19].
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Neoplasm Invasiveness | 2016 |
[Propofol suppresses invasion of human lung cancer A549 cells by down-regulating aquaporin-3 and matrix metalloproteinase-9].
Topics: A549 Cells; Aquaporin 3; Cell Movement; Down-Regulation; Humans; Lung Neoplasms; Matrix Metalloprote | 2016 |
Propofol inhibits invasion and growth of ovarian cancer cells via regulating miR-9/NF-κB signal.
Topics: Apoptosis; Blotting, Western; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Human | 2016 |
Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4).
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Esop | 2017 |
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; GABA Agonist | 2010 |
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; GABA Agonist | 2010 |
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; GABA Agonist | 2010 |
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; GABA Agonist | 2010 |
[Effect of low dose propofol on biological behavior of esophageal squamous cell carcinoma cell line Eca109].
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Respo | 2011 |
Propofol reduces MMPs expression by inhibiting NF-κB activity in human MDA-MB-231 cells.
Topics: Anesthetics, Intravenous; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Gene Expression | 2012 |
Propofol induces proliferation and invasion of gallbladder cancer cells through activation of Nrf2.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Gallbladder Neoplasms; Gene Expression Reg | 2012 |
Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; | 2012 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N | 2002 |
[Anesthetic management of a patient with squeezed heart by huge sternal tumor].
Topics: Anesthesia, Epidural; Anesthesia, General; Bone Neoplasms; Chondrosarcoma; Female; Heart Neoplasms; | 2003 |