propofol has been researched along with Intestinal Diseases in 2 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol could further activate the pathway, which reduced intestinal injury, inhibited apoptosis, reversed inflammation and oxidative stress, and improved the 24-hour survival rate in II/R rats in vivo, and attenuated H/R-induced IEC-6 cell injury, oxidative stress, and apoptosis in vitro, as fine as changes in AICAR treatment." | 5.72 | The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats. ( Chen, Y; Feng, JG; Jia, J; Liu, X; Tan, YF; Wang, MH; Yang, B; Yang, CJ; Zhou, J, 2022) |
| " Minor adverse events were observed in 15." | 3.11 | The performance and safety of motorized spiral enteroscopy, including in patients with surgically altered gastrointestinal anatomy: a multicenter prospective study. ( Al-Toma, A; Beaumont, H; de Ridder, R; Hergelink, DO; Inderson, A; Jacobs, M; Koornstra, JJ; van Boeckel, P; van der Kraan, J, 2022) |
| "Propofol could further activate the pathway, which reduced intestinal injury, inhibited apoptosis, reversed inflammation and oxidative stress, and improved the 24-hour survival rate in II/R rats in vivo, and attenuated H/R-induced IEC-6 cell injury, oxidative stress, and apoptosis in vitro, as fine as changes in AICAR treatment." | 1.72 | The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats. ( Chen, Y; Feng, JG; Jia, J; Liu, X; Tan, YF; Wang, MH; Yang, B; Yang, CJ; Zhou, J, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Toma, A | 1 |
| Beaumont, H | 1 |
| Koornstra, JJ | 1 |
| van Boeckel, P | 1 |
| Hergelink, DO | 1 |
| van der Kraan, J | 1 |
| Inderson, A | 1 |
| de Ridder, R | 1 |
| Jacobs, M | 1 |
| Liu, X | 1 |
| Yang, B | 1 |
| Tan, YF | 1 |
| Feng, JG | 1 |
| Jia, J | 1 |
| Yang, CJ | 1 |
| Chen, Y | 1 |
| Wang, MH | 1 |
| Zhou, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PowerSpiral Enteroscopy: Multicenter Prospective Study on Performance and Safety Including Patients With Altered Gastrointestinal Anatomy[NCT04884113] | 170 participants (Actual) | Observational [Patient Registry] | 2020-03-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for propofol and Intestinal Diseases
| Article | Year |
|---|---|
The performance and safety of motorized spiral enteroscopy, including in patients with surgically altered gastrointestinal anatomy: a multicenter prospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograde; Endosco | 2022 |
1 other study available for propofol and Intestinal Diseases
| Article | Year |
|---|---|
The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Inflammation; Intestinal Diseases; Int | 2022 |