Page last updated: 2024-11-03

propofol and Injuries, Spinal Cord

propofol has been researched along with Injuries, Spinal Cord in 15 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" The SCI rat models were further divided into propofol and dexmedetomidine group for analyzing anesthesia time, duration, post-op analgesia time, SCI sensory function Reuter score."7.85Effects of propofol and dexmedetomidine anesthesia on Th1/Th2 of rat spinal cord injury. ( Feng, WZ; He, FY; Shao, HY; Xu, W; Zhang, YR; Zhong, J, 2017)
"Sixty patients with scoliosis and candidates for PSF surgery were randomly allocated in either alfentanil (PA) or remifentanil (PR) group."5.12Propofol-alfentanil vs propofol-remifentanil for posterior spinal fusion including wake-up test. ( Hassani, V; Imani, F; Jafarian, A; Khan, ZH, 2006)
": To determine the effect of low-dose ketamine on the voltage needed to elicit maximal amplitude of the motor-evoked response to transcranial electrical stimulation during propofol/remifentanil anesthesia in children undergoing scoliosis surgery."5.12Effect of low-dose ketamine on voltage requirement for transcranial electrical motor evoked potentials in children. ( Crawford, MW; Engelhardt, T; Lewis, S; Pehora, C; Strantzas, S; Zaarour, C, 2007)
" The SCI rat models were further divided into propofol and dexmedetomidine group for analyzing anesthesia time, duration, post-op analgesia time, SCI sensory function Reuter score."3.85Effects of propofol and dexmedetomidine anesthesia on Th1/Th2 of rat spinal cord injury. ( Feng, WZ; He, FY; Shao, HY; Xu, W; Zhang, YR; Zhong, J, 2017)
"Propofol can significantly inhibit the accumulation of EAA in spinal cord and provide a protective effect against the ischemia/reperfusion injury induced spinal cord in rabbits."3.75[Effect of propofol on spinal excitatory amino acid accumulation]. ( Wang, Q; Weng, H; Yao, J; Zeng, J; Zhang, Y, 2009)
"Fifteen patients undergoing surgery for scoliosis were anaesthetized with remifentanil and propofol without nitrous oxide or neuromuscular blocking agents (BIS<60)."3.72Influence of propofol concentrations on multipulse transcranial motor evoked potentials. ( Feiss, P; Lacroix, F; Lansade, A; Mouliès, D; Nathan, N; Tabaraud, F; Terrier, G; Viviand, X, 2003)
"When propofol was applied for 4-8 h after kainate washout, strong neuroprotection was observed in all spinal areas, including attenuation of motoneuron loss."1.43Neuroprotective effect of propofol against excitotoxic injury to locomotor networks of the rat spinal cord in vitro. ( Flores Gutiérrez, J; Kaur, J; Nistri, A, 2016)
"Propofol were infused through aorta distal to the occlude sites of the rabbits in the Propofol infusion group continuously with a pump at a rate of 50 mg/kg x 30 min."1.35[Effect of propofol aortic infusion on ischemia-reperfusion spinal cords of rabbits]. ( Liao, ZM; Lin, YJ; Zhang, JF; Zhang, L, 2008)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (60.00)29.6817
2010's6 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, FY1
Feng, WZ1
Zhong, J1
Xu, W1
Shao, HY1
Zhang, YR1
Kato, H1
Nishiwaki, Y1
Hosoi, K1
Shiomi, N1
Hirata, M1
Squair, JW1
Phillips, AA1
Harmon, M1
Krassioukov, AV1
Kaur, J1
Flores Gutiérrez, J1
Nistri, A1
Zeng, J1
Yao, J1
Wang, Q1
Zhang, Y1
Weng, H1
Chang, DJ1
Chang, CH1
Lee, JS1
Jeon, HJ1
Han, DW1
Yamaguchi, K1
Sumitomo, M1
Sesay, M1
Vignes, JR1
Liguoro, D1
Crozat, P1
Boulard, G1
Guerin, J1
Barat, M1
Maurette, P1
Nathan, N1
Tabaraud, F1
Lacroix, F1
Mouliès, D1
Viviand, X1
Lansade, A1
Terrier, G1
Feiss, P1
Hargreaves, SJ1
Watt, JW1
Imani, F1
Jafarian, A1
Hassani, V1
Khan, ZH1
Zaarour, C1
Engelhardt, T1
Strantzas, S1
Pehora, C1
Lewis, S1
Crawford, MW1
Lin, YJ1
Liao, ZM1
Zhang, JF1
Zhang, L1
Lévecque, JP1
Rouquette-Vincenti, I1
Brinquin, L1
Kaptanoglu, E1
Sen, S1
Beskonakli, E1
Surucu, HS1
Tuncel, M1
Kilinc, K1
Taskin, Y1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886]8 participants (Anticipated)Interventional2021-06-08Recruiting
The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388]46 participants (Anticipated)Interventional2020-02-01Not yet recruiting
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923]8 participants (Anticipated)Interventional2021-12-31Recruiting
Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury[NCT05111093]20 participants (Anticipated)Interventional2021-11-29Recruiting
Evaluation of Postoperative Pain by Spectral Analysis of ECG R-R Intervals[NCT00438035]106 participants (Actual)Interventional2007-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for propofol and Injuries, Spinal Cord

ArticleYear
[Autonomic hyperreflexia induced by sacral root stimulation is detected by spectral analysis of the EEG].
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2002, Volume: 49, Issue:9

    Topics: Adolescent; Adult; Anesthetics, Intravenous; Autonomic Dysreflexia; Blood Pressure; Electric Stimula

2002
Propofol-alfentanil vs propofol-remifentanil for posterior spinal fusion including wake-up test.
    British journal of anaesthesia, 2006, Volume: 96, Issue:5

    Topics: Adolescent; Adult; Alfentanil; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Intravenous;

2006
Effect of low-dose ketamine on voltage requirement for transcranial electrical motor evoked potentials in children.
    Spine, 2007, Oct-15, Volume: 32, Issue:22

    Topics: Adolescent; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Dose-Response Relationship,

2007

Other Studies

12 other studies available for propofol and Injuries, Spinal Cord

ArticleYear
Effects of propofol and dexmedetomidine anesthesia on Th1/Th2 of rat spinal cord injury.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:6

    Topics: Anesthesia; Animals; Cytokines; Dexmedetomidine; Propofol; Rats; Spinal Cord Injuries; Th1-Th2 Balan

2017
[Helicopter transportation of a sedated, mechanically ventilated patient with cervical cord injury].
    Masui. The Japanese journal of anesthesiology, 2013, Volume: 62, Issue:9

    Topics: Air Ambulances; Athletic Injuries; Humans; Hypnotics and Sedatives; Male; Neck Injuries; Propofol; R

2013
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Neuroprotective effect of propofol against excitotoxic injury to locomotor networks of the rat spinal cord in vitro.
    The European journal of neuroscience, 2016, Volume: 44, Issue:7

    Topics: Animals; Disease Models, Animal; Electric Stimulation; Kainic Acid; Locomotion; Motor Neurons; Neuro

2016
[Effect of propofol on spinal excitatory amino acid accumulation].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2009, Volume: 23, Issue:6

    Topics: Animals; Excitatory Amino Acids; Female; Male; Propofol; Rabbits; Reperfusion Injury; Spinal Cord; S

2009
Propofol-remifentanil and the ankle clonus test in scoliosis patients.
    Anaesthesia, 2010, Volume: 65, Issue:7

    Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Intravenous; Ankle Joint; Humans; Piperidines;

2010
[Anesthetic management with total intravenous anesthesia for intraoperative wake-up test in pediatric scoliosis surgery].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:12

    Topics: Anesthesia, General; Anesthesia, Intravenous; Child; Female; Humans; Intraoperative Complications; M

2010
Influence of propofol concentrations on multipulse transcranial motor evoked potentials.
    British journal of anaesthesia, 2003, Volume: 91, Issue:4

    Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Electric Stim

2003
Intravenous anaesthesia and repetitive transcranial magnetic stimulation monitoring in spinal column surgery.
    British journal of anaesthesia, 2005, Volume: 94, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Evoked

2005
[Effect of propofol aortic infusion on ischemia-reperfusion spinal cords of rabbits].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2008, Volume: 39, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Interleukin-6; Motor Activity; Neuroprotective Agents; Paraplegia

2008
[Painful injection of propofol into a central vein].
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:3

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Catheterization, Central Venous; Chest Pain; Fe

2000
Antioxidant actions and early ultrastructural findings of thiopental and propofol in experimental spinal cord injury.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Antioxidants; Free Radicals; Lipid Peroxidation; Male; Microscopy

2002