propofol has been researched along with Injuries, Multiple in 13 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol infusion syndrome (PRIS), a rare complication of propofol sedation, is associated with high mortality." | 7.81 | Therapeutic plasma exchange as treatment for propofol infusion syndrome. ( Levin, PD; Levin, V; Rund, D; Sprung, CL; Weissman, C, 2015) |
| "An open, prospective study was carried out on 45 patients with multiple injuries to compare the mortality and incidence of sepsis between those given early total enteral nutrition (TEN) when sedated with propofol and historical controls who had been given total parenteral nutrition (TPN) and sedated with midazolam." | 5.07 | Long-term sedation in the ICU: enteral versus parenteral feeding. ( Bataillie, K; Baute, L; Demeyer, I, 1994) |
| "Propofol infusion syndrome (PRIS), a rare complication of propofol sedation, is associated with high mortality." | 3.81 | Therapeutic plasma exchange as treatment for propofol infusion syndrome. ( Levin, PD; Levin, V; Rund, D; Sprung, CL; Weissman, C, 2015) |
| "Agitation commonly complicates polytrauma presentations, and is treated according to the danger it presents to patient and staff." | 3.01 | Management of Pain and Agitation in Trauma. ( Strayer, RJ, 2023) |
| "Twenty patients, after trauma or major surgery with no intracranial pathology, were randomized to receive either remifentanil/propofol (n=10) or sufentanil/propofol (n=10)." | 2.70 | Recovery after remifentanil and sufentanil for analgesia and sedation of mechanically ventilated patients after trauma or major surgery. ( Biedler, A; Molter, GP; Schöpflin, I; Silomon, M; Soltész, S, 2001) |
| "We studied nine patients with isolated head injuries and 11 multiply injured patients with associated head injuries." | 1.29 | Blood pressure changes in head-injury patients during pre-hospital anaesthesia with propofol. ( Davis, GE; Heath, KJ; Samra, GS; Wilmink, AB; Wilson, AW, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Strayer, RJ | 3 |
| Masquère, P | 1 |
| Lonjaret, L | 1 |
| Fourcade, O | 1 |
| Minville, V | 1 |
| Levin, PD | 1 |
| Levin, V | 1 |
| Weissman, C | 1 |
| Sprung, CL | 1 |
| Rund, D | 1 |
| Pillay, L | 1 |
| Hardcastle, T | 1 |
| Rosen, DJ | 1 |
| Nicoara, A | 1 |
| Koshy, N | 1 |
| Wedderburn, RV | 1 |
| Fowler, SB | 1 |
| Hertzog, J | 1 |
| Wagner, BK | 1 |
| Heath, KJ | 1 |
| Samra, GS | 1 |
| Davis, GE | 1 |
| Wilmink, AB | 1 |
| Wilson, AW | 1 |
| Gaertner, E | 1 |
| Dilovski, K | 1 |
| Bourlon, S | 1 |
| Bistour, L | 1 |
| Pottecher, T | 1 |
| Demeyer, I | 1 |
| Bataillie, K | 1 |
| Baute, L | 1 |
| Takahashi, K | 1 |
| Kitagawa, H | 1 |
| Hirasaki, Y | 1 |
| Albrecht, S | 1 |
| Frenkel, C | 1 |
| Ihmsen, H | 1 |
| Schüttler, J | 1 |
| Soltész, S | 1 |
| Biedler, A | 1 |
| Silomon, M | 1 |
| Schöpflin, I | 1 |
| Molter, GP | 1 |
| Eddleston, JM | 1 |
| Shelly, MP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Study of Induction Medications Used in the Rapid Sequence Intubation of Trauma Patients and a Comparison of Effects on Outcomes[NCT04291521] | 7,000 participants (Anticipated) | Observational | 2024-01-01 | Not yet recruiting | |||
| the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation[NCT02635802] | Phase 4 | 1,500 participants (Anticipated) | Interventional | 2015-12-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for propofol and Injuries, Multiple
| Article | Year |
|---|---|
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Management of Pain and Agitation in Trauma.
Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol | 2023 |
Collective Review of the Status of Rapid Sequence Intubation Drugs of Choice in Trauma in Low- and Middle-Income Settings (Prehospital, Emergency Department and Operating Room Setting).
Topics: Adult; Androstanols; Anesthetics, Dissociative; Anesthetics, Intravenous; Developing Countries; Emer | 2017 |
Too much of a good thing? Tracing the history of the propofol infusion syndrome.
Topics: Accidents, Traffic; Acute Kidney Injury; Adolescent; Adult; Anuria; Brain Injuries; Critical Care; D | 2007 |
Pharmacological interventions for agitation in head-injured patients in the acute care setting.
Topics: Adult; Brain Injuries; Critical Care; Dose-Response Relationship, Drug; Drug Administration Schedule | 1995 |
2 trials available for propofol and Injuries, Multiple
| Article | Year |
|---|---|
Long-term sedation in the ICU: enteral versus parenteral feeding.
Topics: Adult; APACHE; Enteral Nutrition; Female; Humans; Injury Severity Score; Male; Midazolam; Multiple T | 1994 |
Recovery after remifentanil and sufentanil for analgesia and sedation of mechanically ventilated patients after trauma or major surgery.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Combine | 2001 |
7 other studies available for propofol and Injuries, Multiple
| Article | Year |
|---|---|
[Video laryngoscopic tracheal intubation under sedation].
Topics: Aged, 80 and over; Braces; Deep Sedation; Female; Femoral Neck Fractures; Fractures, Bone; Glottis; | 2013 |
Therapeutic plasma exchange as treatment for propofol infusion syndrome.
Topics: Accidents, Traffic; Acidosis, Lactic; Acute Kidney Injury; Adolescent; Anticonvulsants; Biomarkers; | 2015 |
Blood pressure changes in head-injury patients during pre-hospital anaesthesia with propofol.
Topics: Blood Pressure; Craniocerebral Trauma; Emergency Medical Services; Humans; Intubation, Intratracheal | 1994 |
[Locoregional anesthesia of the lower limb at admission of a polytrauma patient with a leg fracture].
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Fentanyl; Fractures, Bone; Humans; Leg Injuries; | 1998 |
The influence of morphine on the level of consciousness in long-term sedation.
Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Conscious Sedation; Consci | 1999 |
A rational approach to the control of sedation in intensive care unit patients based on closed-loop control.
Topics: Adolescent; Adult; Aged; APACHE; Conscious Sedation; Critical Care; Electroencephalography; Female; | 1999 |
The effect on serum lipid concentrations of a prolonged infusion of propofol--hypertriglyceridaemia associated with propofol administration.
Topics: Adolescent; Cholesterol; Cholesterol, HDL; Energy Intake; Fat Emulsions, Intravenous; Humans; Hypert | 1991 |