propofol has been researched along with Inflammation in 92 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study examined how etomidate combined with propofol affected cognitive function, inflammation, and immunity in patients undergoing gastric cancer surgery." | 9.69 | Influences of Etomidate Combined with Propofol on Cognitive Function, Inflammation and Immunity in Patients Undergoing Gastric Cancer Surgery. ( Tian, X, 2023) |
| "The purpose of this study was to investigate the effects of propofol anesthesia combined with remifentanil on inflammation, stress response, and immune function in children undergoing tonsil and adenoid surgery." | 9.51 | Effects of Propofol anesthesia combined with remifentanil on inflammation, stress response and immune function in children undergoing tonsil and adenoid surgery. ( Huang, S; Qin, B; Wang, Z; Wu, X; Yang, X; Zhu, X, 2022) |
| "Propofol is superior to midazolam in reducing inflammation and oxidase stress and in improving post-operation recovery in children with congenital heart disease undergoing cardiac surgery." | 9.15 | Comparison of the effects of propofol and midazolam on inflammation and oxidase stress in children with congenital heart disease undergoing cardiac surgery. ( Liu, Y; Tang, QZ; Xia, WF; Zhou, QS; Zou, HD, 2011) |
| "To compare the effects of an intravenous infusion of propofol and the alpha-2 adrenoceptor, dexmedetomidine, on inflammatory responses and intraabdominal pressure (IAP) in severe sepsis after abdominal surgery, specifically, serum cytokine levels (interleukin [IL]-1, IL-6, and tumor necrosis factor [TNF]-alpha) and IAP." | 9.14 | Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis. ( Memis, D; Sut, N; Tasdogan, M; Yuksel, M, 2009) |
| "Propofol infusion syndrome (PRIS) is a rare and often fatal syndrome described in critically ill children undergoing long-term propofol infusion at high doses." | 8.82 | The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. ( Candiani, A; Latronico, N; Rasulo, F; Vasile, B, 2003) |
| " Propofol (PRO) possesses a positive protective effect on liver ischemia reperfusion injury." | 8.31 | Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS. ( Liao, Q; Liao, Y; Liu, J; Luo, F; Luo, J; Mou, Y, 2023) |
| "Propofol reduced inflammation by up-regulating miR-223-3p, thereby reducing POCD in aged rats." | 8.12 | Propofol alleviates postoperative cognitive dysfunction by inhibiting inflammation via up-regulating miR-223-3p in aged rats. ( Cao, C; Deng, F; Lian, F; Liu, C; Zhou, Z, 2022) |
| "Temozolomide (TMZ) is the first-line drug for the clinical treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits." | 8.12 | Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression. ( Yun, K; Zhao, W, 2022) |
| "To investigate effects of circular RNA (circRNA) 001372 and its antagonist miRNAs-148b-3p on propofol-induced neurotoxicity and neuroinflammation in rat brain and pheochromocytoma cells." | 8.02 | CircRNA 001372 Reduces Inflammation in Propofol-Induced Neuroinflammation and Neural Apoptosis through PIK3CA/Akt/NF-κB by miRNA-148b-3p. ( Suo, L; Wang, M; Yang, S; Zhang, W, 2021) |
| " Propofol has a protective effect on endothelial injury and can suppress inflammation and oxidation." | 8.02 | Propofol alleviates inflammation and apoptosis in HCY‑induced HUVECs by inhibiting endoplasmic reticulum stress. ( Huang, J; Ji, C; Yi, H; Zhang, W; Zheng, M, 2021) |
| "Propofol relieves MIRI and inflammation, reduces the level of oxidative stress and represses I/R-induced myocardial cell apoptosis in MIRI rats by inhibiting the activity of the Rho/Rock signaling pathway." | 8.02 | Propofol relieves inflammation in MIRI rats by inhibiting Rho/Rock signaling pathway. ( Li, Y; Liu, C, 2021) |
| "Propofol ameliorates NP and neuroinflammation of rats by up-regulating PPAR γ expression to block the Wnt/β-catenin pathway." | 8.02 | Propofol ameliorates neuropathic pain and neuroinflammation through PPAR γ up-regulation to block Wnt/β-catenin pathway. ( Hou, Z; Jiang, P; Jiang, Q; Luo, D; Yan, Y, 2021) |
| "This study investigated the role and mechanism of action of propofol on OGD/Rinduced inflammation in mouse N2A neuroblastoma cells." | 7.96 | Propofol Pretreatment Prevents Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-induced Inflammation Through Nuclear Transcription Factor κB (NF-κB) Pathway in Neuroblastoma Cells. ( Hu, F; Jiang, J; Sun, H; Yu, G; Zang, H, 2020) |
| "BACKGROUND This study aimed to investigate the molecular mechanisms associated with the effects of propofol in a rat model of pain due to inflammation following subcutaneous injection with complete Freund's adjuvant (CFA)." | 7.91 | The Molecular Mechanisms Associated with the Effects of Propofol in a Rat Model of Pain Due to Inflammation Following Injection with Complete Freund's Adjuvant. ( Liu, H; Tan, S; Wang, Y; Zhu, S, 2019) |
| "Propofol and dexmedetomidine are commonly used in clinical situations where neuroinflammation may be imminent or even established but comparative data on their effects on neuroinflammatory and cognitive parameters are lacking." | 7.91 | Differential effects of propofol and dexmedetomidine on neuroinflammation induced by systemic endotoxin lipopolysaccharides in adult mice. ( Chang, RC; Chu, JM; Hu, X; Huang, C; Irwin, MG; Ng, OT; Wong, GT; Zhu, S, 2019) |
| "Propofol, an intravenous anesthetic agent widely used in clinical practice, is the preferred anesthetic for asthmatic patients." | 7.88 | Propofol Attenuates Airway Inflammation in a Mast Cell-Dependent Mouse Model of Allergic Asthma by Inhibiting the Toll-like Receptor 4/Reactive Oxygen Species/Nuclear Factor κB Signaling Pathway. ( Huang, YG; Li, HY; Liu, XW; Liu, Z; Meng, JX; Zhao, J, 2018) |
| "Taken together, the present study showed that propofol can protect against sepsis-induced liver dysfunction through suppressing hepatic oxidative stress, lipid peroxidation, inflammation, and drug biotransformation and interactions in the liver." | 7.88 | Sepsis-induced liver dysfunction was ameliorated by propofol via suppressing hepatic lipid peroxidation, inflammation, and drug interactions. ( Chen, JT; Chen, RM; Lee, YW; Lin, YW; Tsai, HC; Wu, GJ, 2018) |
| "We have shown that systemic attenuation of inflammation by the volatile anaesthetic sevoflurane did not translate into attenuated neuro-inflammation in this LPS-induced inflammation model." | 7.85 | Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study. ( Baumann, L; Beck-Schimmer, B; Booy, C; Eugster, P; Hasler, M; Restin, T; Schläpfer, M, 2017) |
| "The aim of this study was to determine the effect of etomidate and propofol pretreatment on the expression of glucocorticoid receptor and the prognosis of sepsis." | 7.81 | Effects of propofol and etomidate pretreatment on glucocorticoid receptor expression following induction of sepsis in rats. ( Li, RM; Liu, N; Shen, L; Wang, C; Xiong, JY; Zhang, Y, 2015) |
| " The aim of this study was to evaluate the effect of propofol on the apoptosis, Aβ accumulation, and inflammation induced by sevoflurane in human neuroglioma cells." | 7.81 | Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells. ( Guo, S; Guo, Y; Jian, L; Tian, Y, 2015) |
| "In an animal model of acute respiratory distress syndrome, sevoflurane ameliorates the lung inflammatory response and improves oxygenation to a greater extent than propofol." | 7.79 | Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study. ( Aguilar, G; Belda, FJ; Ferrando, C; Moreno, J; Piqueras, L; Soro, M, 2013) |
| "Anesthetic propofol has immunomodulatory effects, particularly in the area of anti-inflammation." | 7.77 | Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling. ( Chang, YP; Chen, CL; Chen, YH; Cheng, YL; Choi, PC; Hsieh, CY; Hsing, CH; Huang, WC; Kai, JI; Lin, CF; Lin, MC; Tsai, CC; Wang, CY, 2011) |
| "During hypothermia, propofol administration does not have additive beneficial antiinflammatory effects." | 7.74 | The antiinflammatory effects of propofol in endotoxemic rats during moderate and mild hypothermia. ( Kanakura, H; Taniguchi, T, 2007) |
| " To evaluate the influence of the inflammatory process, we studied in the same patient the sufentanil requirement during procedures that occur during two distinct phases of ulcerative colitis with different inflammatory profiles: (1) left colectomy for major colitis unresponsive to medical treatment during acute inflammation and (2) coloprotectomy with ileoanal anastomosis, three months after recovery of the acute inflammatory episode." | 7.74 | Inflammation affects sufentanil consumption in ulcerative colitis. ( Colombel, JF; Dusson, C; Fleyfel, M; Gambiez, L; Guidat, A; Ousmane, ML; Vallet, B, 2008) |
| "Compared with sevoflurane, propofol administration during suprarenal aortic clamping and unclamping led to modulation of markers of inflammation and decreased NFkappaB expression." | 7.74 | The comparative abilities of propofol and sevoflurane to modulate inflammation and oxidative stress in the kidney after aortic cross-clamping. ( Cascajo, C; García-Criado, FJ; González-Sarmiento, R; Lozano, FS; Muriel, C; Nicolás, JL; Rodríguez-López, JM; Sánchez-Conde, P, 2008) |
| "Propofol is thought to act on gamma-aminobutyric acid receptors, which have some role in pain transmission in the spinal cord." | 7.72 | Intrathecal propofol has analgesic effects on inflammation-induced pain in rats. ( Hanaoka, K; Matsukawa, T; Nishiyama, T, 2004) |
| "Anti-inflammation is important effect of this sedative drug." | 6.94 | The Benefit of Dexmedetomidine on Postoperative Cognitive Function Is Unrelated to the Modulation on Peripheral Inflammation: A Single-center, Prospective, Randomized Study. ( Chen, S; Cheng, X; Gu, E; Han, W; Liu, R; Liu, X; Lu, X; Mei, B; Xu, G; Zhang, Y, 2020) |
| "Propofol has a protective effect on organs; yet, its specific mechanism of action remains unclear." | 5.72 | The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats. ( Chen, Y; Feng, JG; Jia, J; Liu, X; Tan, YF; Wang, MH; Yang, B; Yang, CJ; Zhou, J, 2022) |
| "This study examined how etomidate combined with propofol affected cognitive function, inflammation, and immunity in patients undergoing gastric cancer surgery." | 5.69 | Influences of Etomidate Combined with Propofol on Cognitive Function, Inflammation and Immunity in Patients Undergoing Gastric Cancer Surgery. ( Tian, X, 2023) |
| "Propofol pretreatment also significantly inhibited LPS‑induced cardiomyocyte inflammation and apoptosis." | 5.62 | Propofol ameliorates endotoxin‑induced myocardial cell injury by inhibiting inflammation and apoptosis via the PPARγ/HMGB1/NLRP3 axis. ( Chen, H; Gu, Y; Zhao, H, 2021) |
| "Propofol is a commonly used intravenous anesthetic." | 5.62 | Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis. ( Cai, Y; Chen, J; Cui, C; Guo, Y; Hu, J; Li, H; Lin, G; Nong, L; Sun, K; Sun, Y; Wang, P; Xu, L; Yang, W; Yu, D; Zhang, D, 2021) |
| "The purpose of this study was to investigate the effects of propofol anesthesia combined with remifentanil on inflammation, stress response, and immune function in children undergoing tonsil and adenoid surgery." | 5.51 | Effects of Propofol anesthesia combined with remifentanil on inflammation, stress response and immune function in children undergoing tonsil and adenoid surgery. ( Huang, S; Qin, B; Wang, Z; Wu, X; Yang, X; Zhu, X, 2022) |
| "This is a substudy of a recent randomized controlled trial, which defined the effect of desflurane versus propofol anesthesia on morbidity and mortality in patients undergoing thoracic surgery." | 5.51 | Interleukin-6 Is an Early Plasma Marker of Severe Postoperative Complications in Thoracic Surgery: Exploratory Results From a Substudy of a Randomized Controlled Multicenter Trial. ( Beck-Schimmer, B; Braun, J; Filipovic, M; Neff, SB; Neff, TA; Puhan, M; Rana, D; Schläpfer, M; Seeberger, M; Stüber, F, 2022) |
| "Propofol is a short-acting intravenous anesthetic agent with potential neuroprotective effect." | 5.48 | Delayed treatment of propofol inhibits lipopolysaccharide-induced inflammation in microglia through the PI3K/PKB pathway. ( Huang, B; Liu, M; Luo, J; Luo, T; Zhang, Z, 2018) |
| "Propofol was reported to attenuate endothelial adhesion molecule expression in some situations." | 5.42 | Propofol ameliorates endothelial inflammation induced by hypoxia/reoxygenation in human umbilical vein endothelial cells: Role of phosphatase A2. ( Chen, J; Ding, J; Jiang, H; Kong, L; Miao, C; Sun, Z; Zhu, M, 2015) |
| "Propofol has been shown to attenuate ischemic brain damage via inhibiting neuronal apoptosis." | 5.40 | Propofol reduces inflammatory reaction and ischemic brain damage in cerebral ischemia in rats. ( Chen, JP; Chen, Y; Shi, SS; Tu, XK; Yang, WZ, 2014) |
| " The purpose of this meta-analysis was to compare propofol and sevoflurane with respect to biomarkers of perioperative inflammation." | 5.22 | Inflammatory Biomarker Levels After Propofol or Sevoflurane Anesthesia: A Meta-analysis. ( Atkins, KJ; Evered, LA; Lipszyc, A; O'Bryan, LJ; Scott, DA; Silbert, BS, 2022) |
| "Limb RIPC attenuates acute lung injury via improving intraoperative pulmonary oxygenation in patients without severe pulmonary disease after lung resection under propofol-remifentanil anesthesia." | 5.19 | Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol-remifentanil anesthesia: a randomized controlled study. ( Huang, WQ; Li, C; Li, YS; Liu, KX; Wu, Y; Xu, M, 2014) |
| "Propofol is superior to midazolam in reducing inflammation and oxidase stress and in improving post-operation recovery in children with congenital heart disease undergoing cardiac surgery." | 5.15 | Comparison of the effects of propofol and midazolam on inflammation and oxidase stress in children with congenital heart disease undergoing cardiac surgery. ( Liu, Y; Tang, QZ; Xia, WF; Zhou, QS; Zou, HD, 2011) |
| " The aim of this study was to establish and compare differences in inflammatory response among colorectal cancer surgery patients receiving either total intravenous anesthesia (TIVA) with propofol and remifentanil or inhalational anesthesia (INHAL) with sevoflurane and fentanyl." | 5.15 | Inflammatory response in patients undergoing colorectal cancer surgery: the effect of two different anesthetic techniques. ( Bengtson, JP; Bengtsson, A; Kvarnström, A; Sarbinowski, R; Tylman, M, 2011) |
| "To compare the effects of an intravenous infusion of propofol and the alpha-2 adrenoceptor, dexmedetomidine, on inflammatory responses and intraabdominal pressure (IAP) in severe sepsis after abdominal surgery, specifically, serum cytokine levels (interleukin [IL]-1, IL-6, and tumor necrosis factor [TNF]-alpha) and IAP." | 5.14 | Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis. ( Memis, D; Sut, N; Tasdogan, M; Yuksel, M, 2009) |
| "Propofol infusion syndrome (PRIS) is a rare and often fatal syndrome described in critically ill children undergoing long-term propofol infusion at high doses." | 4.82 | The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. ( Candiani, A; Latronico, N; Rasulo, F; Vasile, B, 2003) |
| " Propofol (PRO) possesses a positive protective effect on liver ischemia reperfusion injury." | 4.31 | Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS. ( Liao, Q; Liao, Y; Liu, J; Luo, F; Luo, J; Mou, Y, 2023) |
| "Propofol reduced inflammation by up-regulating miR-223-3p, thereby reducing POCD in aged rats." | 4.12 | Propofol alleviates postoperative cognitive dysfunction by inhibiting inflammation via up-regulating miR-223-3p in aged rats. ( Cao, C; Deng, F; Lian, F; Liu, C; Zhou, Z, 2022) |
| "Evidences demonstrate that propofol attenuates neuro-inflammation following brain ischemia." | 4.12 | Propofol Rescued Astrocytes from LPS-induced Inflammatory Response via Blocking LncRNA-MEG3/NF-κB Axis. ( Chen, C; Hu, J; Huang, Y; Li, L; Sun, B; Wang, Z; Xia, P; Ye, Z; Zhang, F, 2022) |
| "Temozolomide (TMZ) is the first-line drug for the clinical treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits." | 4.12 | Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression. ( Yun, K; Zhao, W, 2022) |
| " Propofol has a protective effect on endothelial injury and can suppress inflammation and oxidation." | 4.02 | Propofol alleviates inflammation and apoptosis in HCY‑induced HUVECs by inhibiting endoplasmic reticulum stress. ( Huang, J; Ji, C; Yi, H; Zhang, W; Zheng, M, 2021) |
| "To investigate effects of circular RNA (circRNA) 001372 and its antagonist miRNAs-148b-3p on propofol-induced neurotoxicity and neuroinflammation in rat brain and pheochromocytoma cells." | 4.02 | CircRNA 001372 Reduces Inflammation in Propofol-Induced Neuroinflammation and Neural Apoptosis through PIK3CA/Akt/NF-κB by miRNA-148b-3p. ( Suo, L; Wang, M; Yang, S; Zhang, W, 2021) |
| "Propofol relieves MIRI and inflammation, reduces the level of oxidative stress and represses I/R-induced myocardial cell apoptosis in MIRI rats by inhibiting the activity of the Rho/Rock signaling pathway." | 4.02 | Propofol relieves inflammation in MIRI rats by inhibiting Rho/Rock signaling pathway. ( Li, Y; Liu, C, 2021) |
| "Propofol ameliorates NP and neuroinflammation of rats by up-regulating PPAR γ expression to block the Wnt/β-catenin pathway." | 4.02 | Propofol ameliorates neuropathic pain and neuroinflammation through PPAR γ up-regulation to block Wnt/β-catenin pathway. ( Hou, Z; Jiang, P; Jiang, Q; Luo, D; Yan, Y, 2021) |
| "This study investigated the role and mechanism of action of propofol on OGD/Rinduced inflammation in mouse N2A neuroblastoma cells." | 3.96 | Propofol Pretreatment Prevents Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-induced Inflammation Through Nuclear Transcription Factor κB (NF-κB) Pathway in Neuroblastoma Cells. ( Hu, F; Jiang, J; Sun, H; Yu, G; Zang, H, 2020) |
| "BACKGROUND This study aimed to investigate the molecular mechanisms associated with the effects of propofol in a rat model of pain due to inflammation following subcutaneous injection with complete Freund's adjuvant (CFA)." | 3.91 | The Molecular Mechanisms Associated with the Effects of Propofol in a Rat Model of Pain Due to Inflammation Following Injection with Complete Freund's Adjuvant. ( Liu, H; Tan, S; Wang, Y; Zhu, S, 2019) |
| "Propofol and dexmedetomidine are commonly used in clinical situations where neuroinflammation may be imminent or even established but comparative data on their effects on neuroinflammatory and cognitive parameters are lacking." | 3.91 | Differential effects of propofol and dexmedetomidine on neuroinflammation induced by systemic endotoxin lipopolysaccharides in adult mice. ( Chang, RC; Chu, JM; Hu, X; Huang, C; Irwin, MG; Ng, OT; Wong, GT; Zhu, S, 2019) |
| "In the setting of inflammation, rats exposed to isoflurane show increased hypoxia-inducible factor-1α expression despite a lack of hypoxia, increased oxidative stress in the brain, and increased serum lactate, all of which suggest a relative increase in anaerobic metabolism compared to propofol." | 3.91 | Impact of inflammation on brain subcellular energetics in anesthetized rats. ( Ikeda, K; Osuru, HP; Paila, U; Thiele, RH; Zuo, Z, 2019) |
| "Taken together, propofol contributed to liver protection against d-GalN/LPS-induced liver injury in mice by inhibiting inflammation, oxidative stress and hepatocyte apoptosis through regulating TLR4/NF-κB/NLRP3 pathway." | 3.91 | Propofol attenuates inflammatory response and apoptosis to protect d-galactosamine/lipopolysaccharide induced acute liver injury via regulating TLR4/NF-κB/NLRP3 pathway. ( Jiang, K; Tian, L; Zhang, Z, 2019) |
| "Propofol, an intravenous anesthetic agent widely used in clinical practice, is the preferred anesthetic for asthmatic patients." | 3.88 | Propofol Attenuates Airway Inflammation in a Mast Cell-Dependent Mouse Model of Allergic Asthma by Inhibiting the Toll-like Receptor 4/Reactive Oxygen Species/Nuclear Factor κB Signaling Pathway. ( Huang, YG; Li, HY; Liu, XW; Liu, Z; Meng, JX; Zhao, J, 2018) |
| "Taken together, the present study showed that propofol can protect against sepsis-induced liver dysfunction through suppressing hepatic oxidative stress, lipid peroxidation, inflammation, and drug biotransformation and interactions in the liver." | 3.88 | Sepsis-induced liver dysfunction was ameliorated by propofol via suppressing hepatic lipid peroxidation, inflammation, and drug interactions. ( Chen, JT; Chen, RM; Lee, YW; Lin, YW; Tsai, HC; Wu, GJ, 2018) |
| "We have shown that systemic attenuation of inflammation by the volatile anaesthetic sevoflurane did not translate into attenuated neuro-inflammation in this LPS-induced inflammation model." | 3.85 | Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study. ( Baumann, L; Beck-Schimmer, B; Booy, C; Eugster, P; Hasler, M; Restin, T; Schläpfer, M, 2017) |
| " Propofol, a lipid-soluble intravenous anesthetic, has been shown to possess therapeutic benefit during neuroinflammation on various brain injury models." | 3.83 | Propofol Inhibits NLRP3 Inflammasome and Attenuates Blast-Induced Traumatic Brain Injury in Rats. ( Fan, K; Gu, J; Hou, J; Ma, J; Ren, J; Wang, J; Wu, J; Xiao, W; Yu, B, 2016) |
| "The aim of this study was to determine the effect of etomidate and propofol pretreatment on the expression of glucocorticoid receptor and the prognosis of sepsis." | 3.81 | Effects of propofol and etomidate pretreatment on glucocorticoid receptor expression following induction of sepsis in rats. ( Li, RM; Liu, N; Shen, L; Wang, C; Xiong, JY; Zhang, Y, 2015) |
| " The aim of this study was to evaluate the effect of propofol on the apoptosis, Aβ accumulation, and inflammation induced by sevoflurane in human neuroglioma cells." | 3.81 | Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells. ( Guo, S; Guo, Y; Jian, L; Tian, Y, 2015) |
| "In an animal model of acute respiratory distress syndrome, sevoflurane ameliorates the lung inflammatory response and improves oxygenation to a greater extent than propofol." | 3.79 | Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study. ( Aguilar, G; Belda, FJ; Ferrando, C; Moreno, J; Piqueras, L; Soro, M, 2013) |
| "Anesthetic propofol has immunomodulatory effects, particularly in the area of anti-inflammation." | 3.77 | Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling. ( Chang, YP; Chen, CL; Chen, YH; Cheng, YL; Choi, PC; Hsieh, CY; Hsing, CH; Huang, WC; Kai, JI; Lin, CF; Lin, MC; Tsai, CC; Wang, CY, 2011) |
| "During hypothermia, propofol administration does not have additive beneficial antiinflammatory effects." | 3.74 | The antiinflammatory effects of propofol in endotoxemic rats during moderate and mild hypothermia. ( Kanakura, H; Taniguchi, T, 2007) |
| " To evaluate the influence of the inflammatory process, we studied in the same patient the sufentanil requirement during procedures that occur during two distinct phases of ulcerative colitis with different inflammatory profiles: (1) left colectomy for major colitis unresponsive to medical treatment during acute inflammation and (2) coloprotectomy with ileoanal anastomosis, three months after recovery of the acute inflammatory episode." | 3.74 | Inflammation affects sufentanil consumption in ulcerative colitis. ( Colombel, JF; Dusson, C; Fleyfel, M; Gambiez, L; Guidat, A; Ousmane, ML; Vallet, B, 2008) |
| "Compared with sevoflurane, propofol administration during suprarenal aortic clamping and unclamping led to modulation of markers of inflammation and decreased NFkappaB expression." | 3.74 | The comparative abilities of propofol and sevoflurane to modulate inflammation and oxidative stress in the kidney after aortic cross-clamping. ( Cascajo, C; García-Criado, FJ; González-Sarmiento, R; Lozano, FS; Muriel, C; Nicolás, JL; Rodríguez-López, JM; Sánchez-Conde, P, 2008) |
| "After hemorrhage, leukocyte adhesion and CD11b expression increased during thiopental anesthesia, but propofol/fentanyl and ketamine protected against hemorrhage-induced leukocyte adhesion." | 3.73 | Intravenous anesthesia inhibits leukocyte-endothelial interactions and expression of CD11b after hemorrhage. ( Brookes, ZL; Brown, NJ; Lawton, BK; Reilly, CS, 2006) |
| "Propofol is thought to act on gamma-aminobutyric acid receptors, which have some role in pain transmission in the spinal cord." | 3.72 | Intrathecal propofol has analgesic effects on inflammation-induced pain in rats. ( Hanaoka, K; Matsukawa, T; Nishiyama, T, 2004) |
| "Anti-inflammation is important effect of this sedative drug." | 2.94 | The Benefit of Dexmedetomidine on Postoperative Cognitive Function Is Unrelated to the Modulation on Peripheral Inflammation: A Single-center, Prospective, Randomized Study. ( Chen, S; Cheng, X; Gu, E; Han, W; Liu, R; Liu, X; Lu, X; Mei, B; Xu, G; Zhang, Y, 2020) |
| "Propofol does not cause significant inotropic depression at clinically relevant concentrations." | 2.44 | Propofol. ( Camu, F; Vanlersberghe, C, 2008) |
| "Propofol has a protective effect on organs; yet, its specific mechanism of action remains unclear." | 1.72 | The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats. ( Chen, Y; Feng, JG; Jia, J; Liu, X; Tan, YF; Wang, MH; Yang, B; Yang, CJ; Zhou, J, 2022) |
| "Propofol is a commonly used intravenous anesthetic." | 1.62 | Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis. ( Cai, Y; Chen, J; Cui, C; Guo, Y; Hu, J; Li, H; Lin, G; Nong, L; Sun, K; Sun, Y; Wang, P; Xu, L; Yang, W; Yu, D; Zhang, D, 2021) |
| "Propofol pretreatment also significantly inhibited LPS‑induced cardiomyocyte inflammation and apoptosis." | 1.62 | Propofol ameliorates endotoxin‑induced myocardial cell injury by inhibiting inflammation and apoptosis via the PPARγ/HMGB1/NLRP3 axis. ( Chen, H; Gu, Y; Zhao, H, 2021) |
| "Propofol treatment improved VILI, alleviated pulmonary inflammation induced by mechanical ventilation." | 1.56 | Propofol alleviates ventilator-induced lung injury through regulating the Nrf2/NLRP3 signaling pathway. ( Chen, G; Li, W; Ruan, H; Wang, J; Wang, Z; Xia, B; Zhang, M, 2020) |
| "Propofol is an established anesthetic widely used for induction and maintenance of anesthesia." | 1.51 | ( Gao, F; Huang, Y; Li, Y; Lin, H; Liu, J; Peer, J; Tong, Z; Wang, H; Wu, B; Xia, X; Yang, X; Zhao, R; Zheng, JC, 2019) |
| "Propofol is a short-acting intravenous anesthetic agent with potential neuroprotective effect." | 1.48 | Delayed treatment of propofol inhibits lipopolysaccharide-induced inflammation in microglia through the PI3K/PKB pathway. ( Huang, B; Liu, M; Luo, J; Luo, T; Zhang, Z, 2018) |
| "Propofol was reported to attenuate endothelial adhesion molecule expression in some situations." | 1.42 | Propofol ameliorates endothelial inflammation induced by hypoxia/reoxygenation in human umbilical vein endothelial cells: Role of phosphatase A2. ( Chen, J; Ding, J; Jiang, H; Kong, L; Miao, C; Sun, Z; Zhu, M, 2015) |
| "Ninety cancer patients with selective operation from March 2011 to May 2014 were randomly divided into group A (34 cases), group B (28 cases) and group C (28 cases)." | 1.40 | Influence of propofol, isoflurane and enflurance on levels of serum interleukin-8 and interleukin-10 in cancer patients. ( Liu, TC, 2014) |
| "Propofol has been shown to attenuate ischemic brain damage via inhibiting neuronal apoptosis." | 1.40 | Propofol reduces inflammatory reaction and ischemic brain damage in cerebral ischemia in rats. ( Chen, JP; Chen, Y; Shi, SS; Tu, XK; Yang, WZ, 2014) |
| "The wet/dry weight ratio of the lung, lung injury scores, percentage of polymorphonuclear leukocytes, albumin concentration, malondialdehyde, and interleukin-8 levels in bronchoalveolar lavage fluid were significantly increased in both lungs of the reventilation group." | 1.39 | Propofol attenuates pulmonary injury induced by collapse and reventilation of lung in rabbits. ( Bae, HB; Chung, SS; Jeong, CW; Kim, HS; Kim, SJ; Kwak, SH; Lee, SH; Li, M, 2013) |
| "One hundred percent propofol is neither safe nor effective when administered via the IM route; presumably as a result of poor systemic uptake of the hydrophobic drug." | 1.35 | Safety and efficacy of intramuscular propofol administration in rats. ( Brosnan, RJ; Dark, MJ; Haldorson, GJ; McKune, CM, 2008) |
| "Propofol is an intravenous agent used for sedation of ICU patients." | 1.33 | Anti-inflammatory and antioxidative effects of propofol on lipopolysaccharide-activated macrophages. ( Chang, CC; Chang, HC; Chen, RM; Chen, TG; Chen, TL; Lin, LL; Wu, CH, 2005) |
| "Human septic shock can be replicated in the endotoxaemic pig." | 1.31 | Propofol (Diprivan-EDTA) counteracts oxidative injury and deterioration of the arterial oxygen tension during experimental septic shock. ( Basu, S; Eriksson, MB; Kiiski, R; Larsson, AO; Mutschler, DK; Nordgren, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 18 (19.57) | 29.6817 |
| 2010's | 47 (51.09) | 24.3611 |
| 2020's | 27 (29.35) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| O'Bryan, LJ | 1 |
| Atkins, KJ | 1 |
| Lipszyc, A | 1 |
| Scott, DA | 1 |
| Silbert, BS | 1 |
| Evered, LA | 1 |
| Lian, F | 1 |
| Cao, C | 1 |
| Deng, F | 1 |
| Liu, C | 2 |
| Zhou, Z | 1 |
| Zhang, F | 1 |
| Wang, Z | 4 |
| Sun, B | 1 |
| Huang, Y | 2 |
| Chen, C | 1 |
| Hu, J | 2 |
| Li, L | 1 |
| Xia, P | 1 |
| Ye, Z | 1 |
| Zhao, W | 1 |
| Yun, K | 1 |
| Yang, X | 2 |
| Wu, X | 1 |
| Qin, B | 1 |
| Zhu, X | 1 |
| Huang, S | 1 |
| Liu, X | 2 |
| Yang, B | 2 |
| Tan, YF | 1 |
| Feng, JG | 1 |
| Jia, J | 1 |
| Yang, CJ | 1 |
| Chen, Y | 2 |
| Wang, MH | 1 |
| Zhou, J | 1 |
| Li, S | 3 |
| Zhou, Y | 2 |
| Hu, H | 2 |
| Wang, X | 3 |
| Xu, J | 2 |
| Bai, C | 2 |
| Yuan, J | 2 |
| Zhang, D | 3 |
| Gonullu, E | 2 |
| Dagistan, G | 2 |
| Erkin, Y | 2 |
| Erdogan, MA | 2 |
| Erbas, O | 2 |
| Luo, J | 2 |
| Liu, J | 3 |
| Mou, Y | 1 |
| Luo, F | 1 |
| Liao, Q | 1 |
| Liao, Y | 1 |
| Tian, X | 1 |
| Jin, C | 1 |
| Yuan, S | 1 |
| Piao, L | 1 |
| Ren, M | 1 |
| Liu, Q | 1 |
| Sanie-Jahromi, F | 1 |
| Sanie Jahromi, MS | 1 |
| Mei, B | 1 |
| Xu, G | 1 |
| Han, W | 1 |
| Lu, X | 1 |
| Liu, R | 1 |
| Cheng, X | 1 |
| Chen, S | 1 |
| Gu, E | 1 |
| Zhang, Y | 2 |
| Zhang, Z | 2 |
| Tian, L | 1 |
| Jiang, K | 1 |
| Hu, F | 1 |
| Jiang, J | 1 |
| Yu, G | 1 |
| Zang, H | 1 |
| Sun, H | 1 |
| Tan, S | 1 |
| Liu, H | 2 |
| Wang, Y | 1 |
| Zhu, S | 3 |
| Ruan, H | 1 |
| Li, W | 1 |
| Wang, J | 2 |
| Chen, G | 1 |
| Xia, B | 1 |
| Zhang, M | 1 |
| Zeng, R | 1 |
| Dong, S | 1 |
| Wei, Y | 1 |
| Wang, M | 1 |
| Suo, L | 1 |
| Yang, S | 1 |
| Zhang, W | 2 |
| Jiang, P | 1 |
| Jiang, Q | 1 |
| Yan, Y | 1 |
| Hou, Z | 1 |
| Luo, D | 1 |
| Zhao, H | 1 |
| Gu, Y | 1 |
| Chen, H | 1 |
| Li, Y | 3 |
| Ji, C | 1 |
| Yi, H | 1 |
| Huang, J | 1 |
| Zheng, M | 1 |
| Shen, TJ | 1 |
| Chen, CL | 2 |
| Jhan, MK | 1 |
| Tseng, PC | 1 |
| Satria, RD | 1 |
| Hsing, CH | 2 |
| Lin, CF | 2 |
| Yang, Y | 1 |
| Yi, J | 1 |
| Pan, M | 1 |
| Hu, B | 1 |
| Duan, H | 1 |
| Cui, C | 1 |
| Sun, K | 1 |
| Li, H | 1 |
| Xu, L | 1 |
| Lin, G | 1 |
| Guo, Y | 2 |
| Chen, J | 3 |
| Nong, L | 1 |
| Cai, Y | 2 |
| Yu, D | 1 |
| Yang, W | 2 |
| Wang, P | 1 |
| Sun, Y | 1 |
| Neff, TA | 1 |
| Braun, J | 1 |
| Rana, D | 1 |
| Puhan, M | 1 |
| Filipovic, M | 1 |
| Seeberger, M | 1 |
| Stüber, F | 1 |
| Neff, SB | 1 |
| Beck-Schimmer, B | 2 |
| Schläpfer, M | 2 |
| Chalkias, A | 1 |
| Spyropoulos, V | 1 |
| Georgiou, G | 1 |
| Laou, E | 1 |
| Koutsovasilis, A | 1 |
| Pantazopoulos, I | 1 |
| Kolonia, K | 1 |
| Vrakas, S | 1 |
| Papalois, A | 1 |
| Demeridou, S | 1 |
| Gourgoulianis, K | 1 |
| Dontas, I | 1 |
| Kaparos, G | 1 |
| Baka, S | 1 |
| Xanthos, T | 1 |
| Wang, L | 3 |
| Tang, X | 1 |
| Baumann, L | 1 |
| Restin, T | 1 |
| Eugster, P | 1 |
| Hasler, M | 1 |
| Booy, C | 1 |
| Zhang, Q | 2 |
| Chen, B | 1 |
| Zhuo, Q | 1 |
| Bao, C | 1 |
| Lin, L | 1 |
| Zheng, X | 1 |
| Huang, H | 1 |
| Li, M | 2 |
| Liu, M | 2 |
| Luo, T | 2 |
| Pikwer, A | 1 |
| Castegren, M | 1 |
| Namdar, S | 1 |
| Blennow, K | 1 |
| Zetterberg, H | 1 |
| Mattsson, N | 1 |
| Li, HY | 1 |
| Meng, JX | 1 |
| Liu, Z | 1 |
| Liu, XW | 1 |
| Huang, YG | 1 |
| Zhao, J | 1 |
| Barkhuizen, M | 1 |
| van Dijck, FJP | 1 |
| Jellema, RK | 1 |
| Gussenhoven, R | 1 |
| Engelbertink, I | 1 |
| van Mechelen, R | 1 |
| Cleutjens, JPM | 1 |
| Seehase, M | 1 |
| Steinbusch, HWM | 1 |
| Zimmermann, LJ | 1 |
| Gavilanes, AWD | 1 |
| Kramer, BW | 1 |
| Huang, B | 1 |
| Zhou, P | 1 |
| Wu, Y | 2 |
| Chen, D | 1 |
| Hsu, CP | 1 |
| Lin, CH | 1 |
| Kuo, CY | 1 |
| Wu, GJ | 1 |
| Lin, YW | 1 |
| Tsai, HC | 1 |
| Lee, YW | 1 |
| Chen, JT | 1 |
| Chen, RM | 2 |
| Yu, H | 1 |
| Kang, F | 1 |
| Chen, Z | 2 |
| Meng, Y | 1 |
| Dai, M | 1 |
| Cheng, L | 1 |
| Lan, Y | 1 |
| Zheng, L | 1 |
| Wu, F | 1 |
| Roh, GU | 1 |
| Song, Y | 1 |
| Park, J | 1 |
| Ki, YM | 1 |
| Han, DW | 1 |
| Pu, J | 1 |
| Zhou, D | 1 |
| Zhao, L | 1 |
| Yin, M | 1 |
| Hong, J | 1 |
| Xia, X | 1 |
| Zhao, R | 1 |
| Peer, J | 1 |
| Wang, H | 1 |
| Tong, Z | 1 |
| Gao, F | 1 |
| Lin, H | 1 |
| Wu, B | 1 |
| Zheng, JC | 1 |
| Huang, C | 1 |
| Ng, OT | 1 |
| Chu, JM | 1 |
| Irwin, MG | 1 |
| Hu, X | 1 |
| Chang, RC | 1 |
| Wong, GT | 1 |
| Yoon, JY | 1 |
| Kim, DW | 1 |
| Ahn, JH | 1 |
| Choi, EJ | 1 |
| Kim, YH | 1 |
| Jeun, M | 1 |
| Kim, EJ | 1 |
| Thiele, RH | 1 |
| Osuru, HP | 1 |
| Paila, U | 1 |
| Ikeda, K | 1 |
| Zuo, Z | 2 |
| Ferrando, C | 1 |
| Aguilar, G | 1 |
| Piqueras, L | 1 |
| Soro, M | 1 |
| Moreno, J | 1 |
| Belda, FJ | 1 |
| Baki, ED | 1 |
| Aldemir, M | 1 |
| Kokulu, S | 1 |
| Koca, HB | 1 |
| Ela, Y | 1 |
| Sıvacı, RG | 1 |
| Öztürk, NK | 1 |
| Emmiler, M | 1 |
| Adalı, F | 1 |
| Uzel, H | 1 |
| Shi, SS | 1 |
| Yang, WZ | 1 |
| Chen, JP | 1 |
| Tu, XK | 1 |
| Li, C | 1 |
| Xu, M | 1 |
| Li, YS | 1 |
| Huang, WQ | 1 |
| Liu, KX | 1 |
| Liang, G | 1 |
| Khojasteh, S | 1 |
| Wu, Z | 1 |
| Joseph, D | 1 |
| Wei, H | 1 |
| Liu, TC | 1 |
| Rancan, L | 1 |
| Huerta, L | 1 |
| Cusati, G | 1 |
| Erquicia, I | 1 |
| Isea, J | 1 |
| Paredes, SD | 1 |
| García, C | 1 |
| Garutti, I | 1 |
| Simón, C | 1 |
| Vara, E | 1 |
| Potočnik, I | 1 |
| Novak Janković, V | 1 |
| Šostarič, M | 1 |
| Jerin, A | 1 |
| Štupnik, T | 1 |
| Skitek, M | 1 |
| Markovič-Božič, J | 1 |
| Klokočovnik, T | 1 |
| Ji, M | 1 |
| Yang, H | 1 |
| Jin, Z | 1 |
| Zhang, J | 1 |
| Tan, H | 1 |
| Jiang, W | 1 |
| Tian, Y | 1 |
| Guo, S | 1 |
| Jian, L | 1 |
| Wang, C | 1 |
| Liu, N | 1 |
| Li, RM | 1 |
| Shen, L | 1 |
| Xiong, JY | 1 |
| Zhu, M | 1 |
| Ding, J | 1 |
| Jiang, H | 1 |
| Kong, L | 1 |
| Sun, Z | 1 |
| Miao, C | 1 |
| Qiao, Y | 1 |
| Feng, H | 1 |
| Zhao, T | 1 |
| Yan, H | 1 |
| Zhang, H | 1 |
| Zhao, X | 1 |
| Nakanuno, R | 1 |
| Yasuda, T | 1 |
| Hamada, H | 1 |
| Yoshikawa, H | 1 |
| Nakamura, R | 1 |
| Saeki, N | 1 |
| Kawamoto, M | 1 |
| Antkowiak, B | 1 |
| Rudolph, U | 1 |
| Ma, J | 1 |
| Xiao, W | 1 |
| Wu, J | 1 |
| Ren, J | 1 |
| Hou, J | 1 |
| Gu, J | 1 |
| Fan, K | 1 |
| Yu, B | 1 |
| McKune, CM | 1 |
| Brosnan, RJ | 1 |
| Dark, MJ | 1 |
| Haldorson, GJ | 1 |
| Krzych, LJ | 1 |
| Szurlej, D | 1 |
| Bochenek, A | 1 |
| Tasdogan, M | 1 |
| Memis, D | 1 |
| Sut, N | 1 |
| Yuksel, M | 1 |
| Fischer, MJ | 1 |
| Leffler, A | 1 |
| Niedermirtl, F | 1 |
| Kistner, K | 1 |
| Eberhardt, M | 1 |
| Reeh, PW | 1 |
| Nau, C | 1 |
| Tylman, M | 1 |
| Sarbinowski, R | 1 |
| Bengtson, JP | 1 |
| Kvarnström, A | 1 |
| Bengtsson, A | 1 |
| Xia, WF | 1 |
| Liu, Y | 1 |
| Zhou, QS | 1 |
| Tang, QZ | 1 |
| Zou, HD | 1 |
| Schilling, T | 1 |
| Kozian, A | 1 |
| Senturk, M | 1 |
| Huth, C | 1 |
| Reinhold, A | 1 |
| Hedenstierna, G | 1 |
| Hachenberg, T | 1 |
| Lin, MC | 1 |
| Choi, PC | 1 |
| Huang, WC | 1 |
| Kai, JI | 1 |
| Tsai, CC | 1 |
| Cheng, YL | 1 |
| Hsieh, CY | 1 |
| Wang, CY | 1 |
| Chang, YP | 1 |
| Chen, YH | 1 |
| Gui, B | 1 |
| Su, M | 1 |
| Jin, L | 1 |
| Wan, R | 1 |
| Qian, Y | 1 |
| Orosz, JE | 1 |
| Braz, MG | 1 |
| Golim, MA | 1 |
| Barreira, MA | 1 |
| Fecchio, D | 1 |
| Braz, LG | 1 |
| Braz, JR | 1 |
| Bae, HB | 1 |
| Lee, SH | 1 |
| Jeong, CW | 1 |
| Kim, SJ | 1 |
| Kim, HS | 1 |
| Chung, SS | 1 |
| Kwak, SH | 1 |
| Ye, X | 1 |
| Lian, Q | 1 |
| Eckenhoff, MF | 1 |
| Eckenhoff, RG | 1 |
| Pan, JZ | 1 |
| Vasile, B | 1 |
| Rasulo, F | 1 |
| Candiani, A | 1 |
| Latronico, N | 1 |
| Nishiyama, T | 1 |
| Matsukawa, T | 1 |
| Hanaoka, K | 1 |
| Corcoran, TB | 1 |
| Engel, A | 1 |
| Sakamoto, H | 1 |
| O'Callaghan-Enright, S | 1 |
| O'Donnell, A | 1 |
| Heffron, JA | 1 |
| Shorten, G | 1 |
| Longás Valién, J | 1 |
| Guerrero Pardos, LM | 1 |
| Gonzalo González, A | 1 |
| Infantes Morales, M | 1 |
| Rodríguez Zazo, A | 1 |
| Abengochea Beisty, JM | 1 |
| Chen, TG | 1 |
| Chen, TL | 1 |
| Lin, LL | 1 |
| Chang, CC | 1 |
| Chang, HC | 1 |
| Wu, CH | 1 |
| Brookes, ZL | 1 |
| Reilly, CS | 1 |
| Lawton, BK | 1 |
| Brown, NJ | 1 |
| Kanakura, H | 1 |
| Taniguchi, T | 1 |
| Basu, S | 2 |
| Meisert, I | 1 |
| Eggensperger, E | 1 |
| Krieger, E | 1 |
| Krenn, CG | 1 |
| Fleyfel, M | 1 |
| Dusson, C | 1 |
| Ousmane, ML | 1 |
| Guidat, A | 1 |
| Colombel, JF | 1 |
| Gambiez, L | 1 |
| Vallet, B | 1 |
| Vanlersberghe, C | 1 |
| Camu, F | 1 |
| Sánchez-Conde, P | 1 |
| Rodríguez-López, JM | 1 |
| Nicolás, JL | 1 |
| Lozano, FS | 1 |
| García-Criado, FJ | 1 |
| Cascajo, C | 1 |
| González-Sarmiento, R | 1 |
| Muriel, C | 1 |
| Cavalca, V | 1 |
| Colli, S | 1 |
| Veglia, F | 1 |
| Eligini, S | 1 |
| Zingaro, L | 1 |
| Squellerio, I | 1 |
| Rondello, N | 1 |
| Cighetti, G | 1 |
| Tremoli, E | 1 |
| Sisillo, E | 1 |
| Zaloga, GP | 1 |
| Marik, PE | 1 |
| Kotani, N | 1 |
| Hashimoto, H | 1 |
| Kushikata, T | 1 |
| Yoshida, H | 1 |
| Muraoka, M | 1 |
| Takahashi, S | 1 |
| Matsuki, A | 1 |
| Mutschler, DK | 1 |
| Larsson, AO | 1 |
| Kiiski, R | 1 |
| Nordgren, A | 1 |
| Eriksson, MB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Desflurane and Its Effect on Postoperative Morbidity and Mortality in Patients Undergoing Thoracic Surgery[NCT01452256] | Phase 4 | 460 participants (Actual) | Interventional | 2011-12-31 | Completed | ||
| AnaConDa-therapy in COVID-19 Patients[NCT05586126] | 42 participants (Actual) | Observational | 2020-10-01 | Terminated (stopped due to Concerns about possible association between drug and increased ICU mortality) | |||
| Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane[NCT05680545] | 10 participants (Anticipated) | Interventional | 2024-07-01 | Not yet recruiting | |||
| A Randomized Pilot Clinical Trial of the Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction of Sevoflurane in Patient's Whit ARDS Secondary to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2)[NCT04998253] | Early Phase 1 | 24 participants (Actual) | Interventional | 2020-10-01 | Completed | ||
| Correlation Between Blood Pressure, Heart Rate and Plasma Corticotropin, Cortisol Under Surgical Skin Incision[NCT03892538] | 134 participants (Actual) | Observational | 2018-10-01 | Completed | |||
| Phase 1 Study of Antiinflammatory Effect of Sevoflurane in Open Lung Surgery With One-Lung Ventilation[NCT02188407] | Phase 1 | 40 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| Comparison of the Effects of Total Intravenous Anesthesia and Inhalation Anesthesia on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and the Mechanism Involved: a Single-center, Randomized, Prospective Study[NCT03193710] | 260 participants (Anticipated) | Observational | 2017-09-01 | Recruiting | |||
| Impact of Dexmedetomidine Supplemented Analgesia on Long-term Survival in Elderly Patients After Cancer Surgery: a Multicenter Randomized Controlled Trial[NCT03012971] | 1,500 participants (Actual) | Interventional | 2017-01-06 | Active, not recruiting | |||
| Does LOW Dose DEXmedetomidine After Cardiopulmonary Bypass Separation Decrease the Incidence of DELirium: A Double-blind Randomized Placebo-controlled Study (LOWDEXDEL Study)[NCT03388541] | Phase 4 | 420 participants (Actual) | Interventional | 2018-01-17 | Completed | ||
| Impact of Dexmedetomidine Supplemented Analgesia on Incidence of Delirium in Elderly Patients After Cancer Surgery: a Multicenter Randomized Controlled Trial[NCT03012984] | 1,500 participants (Actual) | Interventional | 2017-01-06 | Completed | |||
| Neuroplasticity Induced by General Anaesthesia[NCT04125121] | 20 participants (Actual) | Interventional | 2019-09-26 | Completed | |||
| The Effect of Intraoperative Administration of Dexmedetomidine, Propofol and Midazolam on Postoperative Levels of Inflammatory Markers and Development of Postoperative Cognitive Dysfunction After Pertrochanteric Fracture Surgery.[NCT05398757] | 80 participants (Anticipated) | Interventional | 2022-07-01 | Recruiting | |||
| An Open Label, Pilot Study Utilizing an IV Infusion of Propofol in Male and Female Volunteers With Refractory Chronic Primary Insomnia[NCT02043977] | Phase 1 | 2 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| Epithelial Healing and Visual Outcomes of Patients Using Omega-3 Supplements as an Adjunct Therapy Before and After Photorefractive Keratectomy (PRK) Surgery[NCT01059019] | 17 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for propofol and Inflammation
| Article | Year |
|---|---|
Inflammatory Biomarker Levels After Propofol or Sevoflurane Anesthesia: A Meta-analysis.
Topics: Anesthesia, General; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Biomarkers; C-R | 2022 |
New insights in the systemic and molecular underpinnings of general anesthetic actions mediated by γ-aminobutyric acid A receptors.
Topics: Anesthesia, General; Anesthetics, General; Brain Injuries; GABAergic Neurons; Hippocampus; Humans; I | 2016 |
Rationale for propofol use in cardiac surgery.
Topics: Anesthetics, Intravenous; Brain; Coronary Artery Bypass; Heart; Humans; Inflammation; Myocardial Con | 2009 |
The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome.
Topics: Adult; Animals; Catecholamines; Central Nervous System; Critical Illness; Drug Interactions; Drug Th | 2003 |
Propofol.
Topics: Anesthetics, Intravenous; Animals; Anti-Inflammatory Agents; Central Nervous System; Central Nervous | 2008 |
Propofol.
Topics: Anesthetics, Intravenous; Animals; Anti-Inflammatory Agents; Central Nervous System; Central Nervous | 2008 |
Propofol.
Topics: Anesthetics, Intravenous; Animals; Anti-Inflammatory Agents; Central Nervous System; Central Nervous | 2008 |
Propofol.
Topics: Anesthetics, Intravenous; Animals; Anti-Inflammatory Agents; Central Nervous System; Central Nervous | 2008 |
19 trials available for propofol and Inflammation
| Article | Year |
|---|---|
Effects of Propofol anesthesia combined with remifentanil on inflammation, stress response and immune function in children undergoing tonsil and adenoid surgery.
Topics: Adenoids; Anesthesia, General; C-Reactive Protein; Child; Epinephrine; Humans; Immunity; Inflammatio | 2022 |
Influences of Etomidate Combined with Propofol on Cognitive Function, Inflammation and Immunity in Patients Undergoing Gastric Cancer Surgery.
Topics: Cognition; Etomidate; Humans; Inflammation; Propofol; Stomach Neoplasms | 2023 |
The Benefit of Dexmedetomidine on Postoperative Cognitive Function Is Unrelated to the Modulation on Peripheral Inflammation: A Single-center, Prospective, Randomized Study.
Topics: Aged; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Knee; Cognition; Dexmedetomidine; Humans; | 2020 |
Interleukin-6 Is an Early Plasma Marker of Severe Postoperative Complications in Thoracic Surgery: Exploratory Results From a Substudy of a Randomized Controlled Multicenter Trial.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Biomarkers; Chemokine CCL2; Desflurane; Female; H | 2022 |
Effects of propofol on the inflammatory response during robot-assisted laparoscopic radical prostatectomy: a prospective randomized controlled study.
Topics: Humans; Inflammation; Kidney; Laparoscopy; Male; Middle Aged; Propofol; Prospective Studies; Prostat | 2019 |
Comparison of the effects of desflurane and propofol anesthesia on the inflammatory response and s100β protein during coronary artery bypass grafting.
Topics: Adult; Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiotonic Agents; Cent | 2013 |
Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol-remifentanil anesthesia: a randomized controlled study.
Topics: Acute Lung Injury; Aged; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intravenous; Ca | 2014 |
Antiinflammatory effect of sevoflurane in open lung surgery with one-lung ventilation.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cytokines; Female; Humans; Inflammat | 2014 |
[The effect of mild sedation on the prognosis and inflammatory markers in critical patients with mechanical ventilation].
Topics: Biomarkers; Critical Illness; Humans; Hypnotics and Sedatives; Inflammation; Intensive Care Units; I | 2014 |
Postoperative cognitive dysfunction after inhalational anesthesia in elderly patients undergoing major surgery: the influence of anesthetic technique, cerebral injury and systemic inflammation.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition Disorders; Double-Blind Method; E | 2015 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Hum | 2009 |
Inflammatory response in patients undergoing colorectal cancer surgery: the effect of two different anesthetic techniques.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 2011 |
Comparison of the effects of propofol and midazolam on inflammation and oxidase stress in children with congenital heart disease undergoing cardiac surgery.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Cardiac Surgical Procedures; Child; Female; Heart | 2011 |
Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous | 2011 |
Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous | 2011 |
Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous | 2011 |
Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.
Topics: Adult; Aged; Airway Management; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous | 2011 |
The effects of propofol on lipid peroxidation and inflammatory response in elective coronary artery bypass grafting.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Inflammatory Agents; Coronary Artery B | 2004 |
[Comparison of 4 techniques for general anesthesia for carotid endarterectomy: inflammatory response, cardiocirculatory complications, and postoperative analgesia].
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiovascular Disease | 2004 |
Time course and attenuation of ischaemia-reperfusion induced oxidative injury by propofol in human renal transplantation.
Topics: Aged; Anesthetics, Intravenous; Antioxidants; F2-Isoprostanes; Female; Humans; Inflammation; Kidney | 2007 |
Anesthetic propofol enhances plasma gamma-tocopherol levels in patients undergoing cardiac surgery.
Topics: Aged; Aged, 80 and over; alpha-Tocopherol; Anesthetics, Inhalation; Anesthetics, Intravenous; Biomar | 2008 |
Intraoperative prostaglandin E1 improves antimicrobial and inflammatory responses in alveolar immune cells.
Topics: Adult; Alprostadil; Anesthetics, Intravenous; Blood Bactericidal Activity; Bronchoalveolar Lavage Fl | 2001 |
68 other studies available for propofol and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Propofol alleviates postoperative cognitive dysfunction by inhibiting inflammation via up-regulating miR-223-3p in aged rats.
Topics: Animals; Cognitive Dysfunction; Humans; Inflammation; Isoflurane; MicroRNAs; Postoperative Cognitive | 2022 |
Propofol Rescued Astrocytes from LPS-induced Inflammatory Response via Blocking LncRNA-MEG3/NF-κB Axis.
Topics: Animals; Astrocytes; Cytokines; Inflammation; Lipopolysaccharides; NF-kappa B; Propofol; Rats; RNA, | 2022 |
Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Dru | 2022 |
The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Inflammation; Intestinal Diseases; Int | 2022 |
SIRT3 Enhances the Protective Role of Propofol in Postoperative Cognitive Dysfunction via Activating Autophagy Mediated by AMPK/mTOR Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Inflammation; Lipopolysaccharides; Mice; Mice, In | 2022 |
SIRT3 Enhances the Protective Role of Propofol in Postoperative Cognitive Dysfunction via Activating Autophagy Mediated by AMPK/mTOR Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Inflammation; Lipopolysaccharides; Mice; Mice, In | 2022 |
SIRT3 Enhances the Protective Role of Propofol in Postoperative Cognitive Dysfunction via Activating Autophagy Mediated by AMPK/mTOR Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Inflammation; Lipopolysaccharides; Mice; Mice, In | 2022 |
SIRT3 Enhances the Protective Role of Propofol in Postoperative Cognitive Dysfunction via Activating Autophagy Mediated by AMPK/mTOR Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Inflammation; Lipopolysaccharides; Mice; Mice, In | 2022 |
Demonstration of the protective effect of propofol in rat model of cisplatin-induced neuropathy.
Topics: Animals; Antioxidants; Cisplatin; Glutathione; Inflammation; Interleukin-6; Lipid Peroxidation; Malo | 2023 |
Demonstration of the protective effect of propofol in rat model of cisplatin-induced neuropathy.
Topics: Animals; Antioxidants; Cisplatin; Glutathione; Inflammation; Interleukin-6; Lipid Peroxidation; Malo | 2023 |
Demonstration of the protective effect of propofol in rat model of cisplatin-induced neuropathy.
Topics: Animals; Antioxidants; Cisplatin; Glutathione; Inflammation; Interleukin-6; Lipid Peroxidation; Malo | 2023 |
Demonstration of the protective effect of propofol in rat model of cisplatin-induced neuropathy.
Topics: Animals; Antioxidants; Cisplatin; Glutathione; Inflammation; Interleukin-6; Lipid Peroxidation; Malo | 2023 |
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
Topics: Animals; Inflammation; Ischemia; Liver; Liver Cirrhosis; Mice; Propofol; Reperfusion; Reperfusion In | 2023 |
Propofol synergizes with circAPBB2 to protect against hypoxia/reoxygenation-induced oxidative stress, inflammation, and apoptosis of human cardiomyocytes.
Topics: Apoptosis; Humans; Hypoxia; Inflammation; MicroRNAs; Myocytes, Cardiac; Oxidative Stress; Propofol | 2023 |
In Vitro Effect of Propofol on the Expression of Genes Involved in Inflammation and Apoptosis in Corneal Activated Keratocytes.
Topics: Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Corneal Keratocytes; Humans; Inflammation; I | 2024 |
Propofol attenuates inflammatory response and apoptosis to protect d-galactosamine/lipopolysaccharide induced acute liver injury via regulating TLR4/NF-κB/NLRP3 pathway.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Chemical and Drug Induced Liver Injury; Cytokines; Dis | 2019 |
Propofol Pretreatment Prevents Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-induced Inflammation Through Nuclear Transcription Factor κB (NF-κB) Pathway in Neuroblastoma Cells.
Topics: Animals; Cell Line, Tumor; Cell Survival; Glucose; Inflammation; Interleukin-1beta; Mice; Neuroblast | 2020 |
The Molecular Mechanisms Associated with the Effects of Propofol in a Rat Model of Pain Due to Inflammation Following Injection with Complete Freund's Adjuvant.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Freund's Adjuvant; Inflammasomes; Inflammation; I | 2019 |
Propofol alleviates ventilator-induced lung injury through regulating the Nrf2/NLRP3 signaling pathway.
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Lung; Mice; Mitochondria; NF-E2-Related Facto | 2020 |
Influences of different doses of nalbuphine combined with propofol on the anesthetic effects, hemodynamics, inflammation and immunity of patients undergoing hysteroscopic surgery.
Topics: Anesthetics; Female; Hemodynamics; Humans; Hysteroscopy; Inflammation; Nalbuphine; Pregnancy; Propof | 2023 |
CircRNA 001372 Reduces Inflammation in Propofol-Induced Neuroinflammation and Neural Apoptosis through PIK3CA/Akt/NF-κB by miRNA-148b-3p.
Topics: Animals; Apoptosis; Class I Phosphatidylinositol 3-Kinases; Inflammation; MicroRNAs; NF-kappa B; Pho | 2021 |
Propofol ameliorates neuropathic pain and neuroinflammation through PPAR γ up-regulation to block Wnt/β-catenin pathway.
Topics: Anesthetics, Intravenous; Animals; Inflammation; Male; Neuralgia; PPAR gamma; Propofol; Rats; Rats, | 2021 |
Propofol ameliorates endotoxin‑induced myocardial cell injury by inhibiting inflammation and apoptosis via the PPARγ/HMGB1/NLRP3 axis.
Topics: Animals; Apoptosis; HMGB1 Protein; Inflammation; Lipopolysaccharides; Male; Myocardium; NLR Family, | 2021 |
Propofol relieves inflammation in MIRI rats by inhibiting Rho/Rock signaling pathway.
Topics: Animals; Antioxidants; Apoptosis; Enzyme Inhibitors; Inflammation; Myocardial Reperfusion Injury; Ox | 2021 |
Propofol alleviates inflammation and apoptosis in HCY‑induced HUVECs by inhibiting endoplasmic reticulum stress.
Topics: Apoptosis; Atherosclerosis; Cell Survival; Endoplasmic Reticulum Stress; Homocysteine; Human Umbilic | 2021 |
Antiviral Efficacy of the Anesthetic Propofol against Dengue Virus Infection and Cellular Inflammation.
Topics: Anesthetics; Animals; Anti-Inflammatory Agents; Antiviral Agents; Cell Line; Dengue; Dengue Virus; H | 2021 |
Edaravone alleviated propofol-induced neural injury in developing rats by BDNF/TrkB pathway.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cells, Cultured; Edaravone; Hypnotics | 2021 |
Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis.
Topics: Animals; Brain Injuries, Traumatic; Inflammation; Male; MicroRNAs; NF-kappa B; NFATC Transcription F | 2021 |
Baseline Values and Kinetics of IL-6, Procalcitonin, and TNF-
Topics: Anesthesia; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Animals; Cytokine | 2021 |
Propofol promotes migration, alleviates inflammation, and apoptosis of lipopolysaccharide-induced human pulmonary microvascular endothelial cells by activating PI3K/AKT signaling pathway via upregulating APOM expression.
Topics: Acute Lung Injury; Apolipoproteins M; Apoptosis; Cytokines; Endothelial Cells; Humans; Inflammation; | 2022 |
Sevoflurane attenuates systemic inflammation compared with propofol, but does not modulate neuro-inflammation: A laboratory rat study.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Inflammation; Inflammation Mediators; Li | 2017 |
Propofol inhibits NF-κB activation to ameliorate airway inflammation in ovalbumin (OVA)-induced allergic asthma mice.
Topics: Allergens; Anesthetics; Animals; Anti-Allergic Agents; Asthma; Cell Line; Disease Models, Animal; Hu | 2017 |
Propofol Attenuates Inflammatory Response in LPS-Activated Microglia by Regulating the miR-155/SOCS1 Pathway.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regu | 2018 |
Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer's disease, and neuronal injury in humans: a cohort study.
Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Anesthesia, Intravenous; Biomarkers; Cohort Studies | 2017 |
Propofol Attenuates Airway Inflammation in a Mast Cell-Dependent Mouse Model of Allergic Asthma by Inhibiting the Toll-like Receptor 4/Reactive Oxygen Species/Nuclear Factor κB Signaling Pathway.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Inflammation; Mast Cells; Mice; NF-kappa B; Propofol; | 2018 |
The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb.
Topics: Anesthetics; Animals; Animals, Newborn; Brain Mapping; Dopamine; Dopaminergic Neurons; Female; Gluta | 2018 |
Delayed treatment of propofol inhibits lipopolysaccharide-induced inflammation in microglia through the PI3K/PKB pathway.
Topics: Animals; Cyclooxygenase 2; Inflammation; Lipopolysaccharides; Mice; Microglia; Nitric Oxide Synthase | 2018 |
Propofol Promotes Ankle Fracture Healing in Children by Inhibiting Inflammatory Response.
Topics: Ankle Joint; Bradykinin; Cell Death; Cell Line, Tumor; Child; Cytokines; Female; Fracture Healing; F | 2018 |
Endothelial-cell inflammation and damage by reactive oxygen species are prevented by propofol via ABCA1-mediated cholesterol efflux.
Topics: Animals; Aorta; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol; | 2018 |
Sepsis-induced liver dysfunction was ameliorated by propofol via suppressing hepatic lipid peroxidation, inflammation, and drug interactions.
Topics: Animals; Drug Interactions; Inflammation; Interleukin-1beta; Interleukin-4; Lipid Peroxidation; Live | 2018 |
Propofol attenuates inflammatory damage on neurons following cerebral infarction by inhibiting excessive activation of microglia.
Topics: Actins; Animals; Brain Infarction; Cell Death; Cell Movement; Cell Proliferation; Cytoskeleton; Dise | 2019 |
Propofol partially attenuates complete freund's adjuvant-induced neuroinflammation through inhibition of the ERK1/2/NF-κB pathway.
Topics: Animals; Disease Models, Animal; Freund's Adjuvant; Gene Expression Regulation; Humans; Inflammation | 2019 |
Propofol Alleviates Apoptosis Induced by Chronic High Glucose Exposure via Regulation of HIF-1
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Gene Expression Regulation; Glucose; Hypoxia-Inducible | 2019 |
Topics: Anti-Inflammatory Agents; Cell Line; Cell Line, Tumor; Culture Media, Conditioned; Culture Media, Se | 2019 |
Differential effects of propofol and dexmedetomidine on neuroinflammation induced by systemic endotoxin lipopolysaccharides in adult mice.
Topics: Animals; Antioxidants; Brain; Cognition Disorders; Dexmedetomidine; Hippocampus; Hypnotics and Sedat | 2019 |
Propofol Suppresses LPS-Induced Inflammation in Amnion Cells via Inhibition of NF-κB Activation.
Topics: Amnion; Cyclooxygenase 2; Cytokines; Dinoprostone; Female; Humans; Inflammation; Interleukin-1beta; | 2019 |
Impact of inflammation on brain subcellular energetics in anesthetized rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Brain; Electron Tra | 2019 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Propofol reduces inflammatory reaction and ischemic brain damage in cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Cyclooxygenase 2; Infarction, Middle Cerebral Artery; | 2014 |
Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane.
Topics: Administration, Inhalation; Anesthetics; Animals; Animals, Newborn; Apoptosis; Brain Damage, Chronic | 2014 |
Influence of propofol, isoflurane and enflurance on levels of serum interleukin-8 and interleukin-10 in cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Enflurane; Female; Humans; Inflammat | 2014 |
Sevoflurane prevents liver inflammatory response induced by lung ischemia-reperfusion.
Topics: Anesthetics, Inhalation; Animals; C-Reactive Protein; Caspase 3; Chemokine CCL2; Ferritins; Hemodyna | 2014 |
The choice of general anesthetics may not affect neuroinflammation and impairment of learning and memory after surgery in elderly rats.
Topics: Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Buprenorphine; Cal | 2015 |
Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells.
Topics: Amyloid beta-Peptides; Anesthetics; Apoptosis; Glioma; Humans; Inflammation; Methyl Ethers; Neurogli | 2015 |
Effects of propofol and etomidate pretreatment on glucocorticoid receptor expression following induction of sepsis in rats.
Topics: Adrenal Cortex; Animals; Etomidate; Female; Inflammation; Propofol; Rats; Rats, Sprague-Dawley; Rece | 2015 |
Propofol ameliorates endothelial inflammation induced by hypoxia/reoxygenation in human umbilical vein endothelial cells: Role of phosphatase A2.
Topics: Anti-Inflammatory Agents; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Dose-Response Rel | 2015 |
Propofol for Anesthesia and Postoperative Sedation Resulted in Fewer Inflammatory Responses than Sevoflurane Anesthesia and Midazolam Sedation after Thoracoabdominal Esophagectomy.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Esophagectomy; Humans; Inflammation; Methyl Ether | 2015 |
Propofol Inhibits NLRP3 Inflammasome and Attenuates Blast-Induced Traumatic Brain Injury in Rats.
Topics: Animals; Brain Injuries, Traumatic; Cerebral Cortex; Cytokines; Inflammasomes; Inflammation; NLR Fam | 2016 |
Safety and efficacy of intramuscular propofol administration in rats.
Topics: Anesthesia; Animals; Dose-Response Relationship, Drug; Female; Hypnotics and Sedatives; Inflammation | 2008 |
The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors.
Topics: Anesthetics, Intravenous; Animals; Calcitonin Gene-Related Peptide; GABA Antagonists; Ganglia, Spina | 2010 |
Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling.
Topics: Anesthetics, Intravenous; Animals; Cell Death; Cytokines; Endotoxins; Enzyme Activation; I-kappa B K | 2011 |
Neuroprotective effects of pretreatment with propofol in LPS-induced BV-2 microglia cells: role of TLR4 and GSK-3β.
Topics: Anesthetics, Intravenous; Animals; Cell Line; Cell Survival; Down-Regulation; Glycogen Synthase Kina | 2012 |
Cytokine profile in patients undergoing minimally invasive surgery with balanced anesthesia.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Balanced Anesthesia; Cytokines; Female; Fe | 2012 |
Propofol attenuates pulmonary injury induced by collapse and reventilation of lung in rabbits.
Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Inflammati | 2013 |
Differential general anesthetic effects on microglial cytokine expression.
Topics: Alzheimer Disease; Anesthetics; Cells, Cultured; Cytokines; Gene Expression Regulation; Humans; Infl | 2013 |
Intrathecal propofol has analgesic effects on inflammation-induced pain in rats.
Topics: Analgesics; Animals; Disease Models, Animal; Formaldehyde; Hot Temperature; Inflammation; Injections | 2004 |
Anti-inflammatory and antioxidative effects of propofol on lipopolysaccharide-activated macrophages.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Survival; Gene Expression Regulatio | 2005 |
Intravenous anesthesia inhibits leukocyte-endothelial interactions and expression of CD11b after hemorrhage.
Topics: Anesthesia, Intravenous; Animals; CD11b Antigen; Cell Adhesion; Endothelial Cells; Endothelium, Vasc | 2006 |
The antiinflammatory effects of propofol in endotoxemic rats during moderate and mild hypothermia.
Topics: Anesthetics, Intravenous; Animals; Anti-Inflammatory Agents; Blood Gas Analysis; Blood Pressure; Dis | 2007 |
Inflammation affects sufentanil consumption in ulcerative colitis.
Topics: Acute Disease; Adolescent; Adult; Anastomosis, Surgical; Anesthetics, Inhalation; Anesthetics, Intra | 2008 |
The comparative abilities of propofol and sevoflurane to modulate inflammation and oxidative stress in the kidney after aortic cross-clamping.
Topics: Animals; Aorta, Abdominal; Constriction; Inflammation; Kidney; Male; Methyl Ethers; Oxidative Stress | 2008 |
Not all propofol is created equal.
Topics: Animals; Chemistry, Pharmaceutical; Drug Carriers; Endotoxemia; Free Radical Scavengers; Humans; Hyp | 2001 |
Propofol (Diprivan-EDTA) counteracts oxidative injury and deterioration of the arterial oxygen tension during experimental septic shock.
Topics: Anesthetics, Intravenous; Animals; Dinoprost; Endotoxemia; Escherichia coli Infections; F2-Isoprosta | 2001 |