Page last updated: 2024-11-03

propofol and Idiopathic Parkinson Disease

propofol has been researched along with Idiopathic Parkinson Disease in 37 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" Due to a potential role of local field potentials (LFPs) in DBS functional mapping, we characterized the effect of propofol on globus pallidus interna (GPi) and externa (GPe) LFPs in Parkinson disease (PD) patients."7.88Propofol Anesthesia Precludes LFP-Based Functional Mapping of Pallidum during DBS Implantation. ( AuYong, N; Hudson, A; Malekmohammadi, M; Pouratian, N; Sparks, H, 2018)
"2 μg·kg·h) on local field potentials in patients with Parkinson disease undergoing deep brain stimulation surgery compared with control recording (primary outcome), as well as the effect of propofol at different estimated peak effect site concentrations (0."7.85Effect of Dexmedetomidine and Propofol on Basal Ganglia Activity in Parkinson Disease: A Controlled Clinical Trial. ( Alegre, M; Cacho-Asenjo, E; Carmona-Abellán, M; Guridi, J; Honorato-Cia, C; Martinez-Simon, A; Nuñez-Cordoba, JM; Trocóniz, IF; Valencia, M, 2017)
" This study reports a population pharmacodynamic model of propofol sedation and airway obstruction in the Parkinson disease population."7.71Modeling of the sedative and airway obstruction effects of propofol in patients with Parkinson disease undergoing stereotactic surgery. ( Carrero, E; Fábregas, N; Gambús, PL; Nalda-Felipe, MA; Rapado, J; Salvador, L; Trocóniz, IF; Valero, R, 2002)
"Propofol is an intravenous sedative-hypnotic agent that is commonly used to induce and maintain general anaesthesia."5.43Effects of Propofol on Oxidative Stress Parameters in Selected Parts of the Brain in a Rat Model of Parkinson Disease. ( Birkner, E; Chwalińska, E; Hudziec, E; Nowak, P; Prudel, B; Romuk, E; Skowron, M; Szczurek, W, 2016)
"Propofol was administered at a dose of 60 mg/kg body weight/IP, 60 minutes before decapitation."5.42Influence of propofol on oxidative-antioxidative system parameters in peripheral organs of rats with Parkinson disease. ( Birkner, E; Kwiecień, I; Nowak, P; Romuk, E; Stolecka, D; Szczurek, W, 2015)
" During induction of anesthesia with propofol (n = 13) or sevoflurane (n = 12) alone, cortical (EEG) and subcortical (ESCoG) electrogenesis were obtained, respectively, from a frontal montage (F3-C3) and through the deep-brain electrode (p0-p3)."5.12Differential dynamic of action on cortical and subcortical structures of anesthetic agents during induction of anesthesia. ( Bruder, NJ; Gouin, FM; Gouvitsos, FA; Peragut, JC; Regis, JM; Rey, MF; Velly, LJ; Witjas, T, 2007)
"The authors recorded local field potentials from sensorimotor cortices in patients with Parkinson disease (N = 12) and essential tremor (N = 7) undergoing deep brain stimulation surgery, before and after propofol-induced loss of consciousness."3.88Propofol-induced Changes in α-β Sensorimotor Cortical Connectivity. ( AuYong, N; Hudson, AE; Malekmohammadi, M; Pouratian, N; Price, CM; Tsolaki, E, 2018)
" Due to a potential role of local field potentials (LFPs) in DBS functional mapping, we characterized the effect of propofol on globus pallidus interna (GPi) and externa (GPe) LFPs in Parkinson disease (PD) patients."3.88Propofol Anesthesia Precludes LFP-Based Functional Mapping of Pallidum during DBS Implantation. ( AuYong, N; Hudson, A; Malekmohammadi, M; Pouratian, N; Sparks, H, 2018)
"2 μg·kg·h) on local field potentials in patients with Parkinson disease undergoing deep brain stimulation surgery compared with control recording (primary outcome), as well as the effect of propofol at different estimated peak effect site concentrations (0."3.85Effect of Dexmedetomidine and Propofol on Basal Ganglia Activity in Parkinson Disease: A Controlled Clinical Trial. ( Alegre, M; Cacho-Asenjo, E; Carmona-Abellán, M; Guridi, J; Honorato-Cia, C; Martinez-Simon, A; Nuñez-Cordoba, JM; Trocóniz, IF; Valencia, M, 2017)
" This study reports a population pharmacodynamic model of propofol sedation and airway obstruction in the Parkinson disease population."3.71Modeling of the sedative and airway obstruction effects of propofol in patients with Parkinson disease undergoing stereotactic surgery. ( Carrero, E; Fábregas, N; Gambús, PL; Nalda-Felipe, MA; Rapado, J; Salvador, L; Trocóniz, IF; Valero, R, 2002)
"We report two patients presenting for thalamotomy in whom tremor was abolished for 8 h after propofol anaesthesia."3.69Propofol--contrasting effects in movement disorders. ( Anderson, BJ; Futter, ME; Marks, PV, 1994)
"An increasing number of patients with Parkinson's disease (PD) will have surgery under general anesthesia."3.01Minimum Alveolar Concentration-Awake of Sevoflurane is Decreased in Patients with Parkinson's Disease: An Up-and-Down Sequential Allocation Trial. ( Dong, M; Huang, X; Kang, F; Li, J; Meng, W; Wang, S; Yang, C; Zuo, Z, 2021)
"In 6 patients with Parkinson's disease and 1 with cerebral palsy, muscle afferent-evoked thalamic potentials (METPs) were recorded in the ventral intermediate (Vim) nucleus."2.69Thalamic potentials evoked by motor point stimulation. ( Fukuda, M; Kameyama, S; Tanaka, R, 2000)
"Twelve patients with advanced Parkinson's disease, who were undergoing deep brain stimulation (DBS) electrode implantation in the subthalamic nucleus (STN), were included in this study."1.56Dynamic changes in rhythmic and arrhythmic neural signatures in the subthalamic nucleus induced by anaesthesia and tracheal intubation. ( Aziz, TZ; Fitzgerald, JJ; Gillies, MJ; Green, AL; Hu, K; Huang, P; Huang, Y; Li, D; Ma, X; Martin, S; Pan, Y; Sun, B; Tan, H; Wang, S; Zhan, S, 2020)
"Propofol is an intravenous sedative-hypnotic agent that is commonly used to induce and maintain general anaesthesia."1.43Effects of Propofol on Oxidative Stress Parameters in Selected Parts of the Brain in a Rat Model of Parkinson Disease. ( Birkner, E; Chwalińska, E; Hudziec, E; Nowak, P; Prudel, B; Romuk, E; Skowron, M; Szczurek, W, 2016)
"Propofol was administered at a dose of 60 mg/kg body weight/IP, 60 minutes before decapitation."1.42Influence of propofol on oxidative-antioxidative system parameters in peripheral organs of rats with Parkinson disease. ( Birkner, E; Kwiecień, I; Nowak, P; Romuk, E; Stolecka, D; Szczurek, W, 2015)
"We analyzed 8 patients with Parkinson's disease, underwent bilateral STN DBS with MER."1.40Influence of propofol and fentanyl on deep brain stimulation of the subthalamic nucleus. ( Hwang, JH; Jeon, BS; Kim, C; Kim, DG; Kim, HC; Kim, HJ; Kim, IK; Kim, IY; Kim, JW; Kim, MR; Kim, W; Kim, YE; Lee, WW; Lim, YH; Paek, SH; Park, HP; Song, IH; Song, SW, 2014)
"Patients with Parkinson's disease frequently suffer from impaired autonomic nervous function."1.37[Effects of the induction of anesthesia with propofol on hemodynamics in patients with Parkinson's disease]. ( Gokan, D; Iwasaki, K; Kato, J; Nakajima, R; Ogawa, S; Ogawa, Y, 2011)
"Low-dose propofol in one other dystonia patient also seemed to suppress GPi firing."1.32Pallidal neuronal activity: implications for models of dystonia. ( Dostrovsky, JO; Hutchison, WD; Lang, AE; Lozano, AM, 2003)
"The propofol dose was 890."1.32[Preoperative adverse events during stereotactic microelectrode-guided deep brain surgery in Parkinson's disease]. ( Arguis, MJ; Carrero, E; Fàbregas, N; Rumià, J; Salvador, L; Santos, P; Valero, R; Valldeoriola, F, 2004)
"In 28 patients with Parkinson's disease including seven juvenile cases of parkinsonism, the postoperative motor and ADL scores on the Unified Parkinson's Disease Rating Scale significantly improved."1.30[Stereotaxy during intravenous anesthesia with propofol]. ( Fukuda, M; Kameyama, S; Kawaguchi, T; Tanaka, R; Yamashita, S, 1998)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (16.22)18.2507
2000's10 (27.03)29.6817
2010's13 (35.14)24.3611
2020's8 (21.62)2.80

Authors

AuthorsStudies
Nakajima, A1
Iwamuro, H1
Tokugawa, J1
Odo, M1
Shimo, Y1
Vinckier, F1
Gaillard, R1
Taylor, G1
Murray, GK1
Plaze, M1
Bourdillon, P1
Perin-Dureau, F1
Erdman, HB1
Kornilov, E1
Kahana, E1
Zarchi, O1
Reiner, J1
Socher, A1
Strauss, I1
Firman, S1
Israel, Z4
Bergman, H4
Tamir, I1
Meng, W2
Kang, F2
Dong, M2
Wang, S4
Han, M1
Huang, X2
Li, J3
Yang, C2
Wang, P1
Zhao, L1
Wang, T1
Mei, W1
An, Y1
Li, L1
Li, Z1
Huang, Y1
Hu, K1
Green, AL1
Ma, X1
Gillies, MJ1
Fitzgerald, JJ1
Pan, Y1
Martin, S1
Huang, P1
Zhan, S1
Li, D1
Tan, H1
Aziz, TZ1
Sun, B1
Benady, A1
Zadik, S1
Eimerl, D2
Heymann, S1
Raz, A2
Zuo, Z1
Martinez-Simon, A1
Alegre, M1
Honorato-Cia, C1
Nuñez-Cordoba, JM1
Cacho-Asenjo, E1
Trocóniz, IF2
Carmona-Abellán, M1
Valencia, M1
Guridi, J1
Malekmohammadi, M2
AuYong, N2
Price, CM1
Tsolaki, E1
Hudson, AE1
Pouratian, N2
Myrov, V1
Sedov, A1
Salova, E1
Tomskiy, A1
Belova, E1
Sparks, H1
Hudson, A1
Kim, W1
Song, IH2
Lim, YH2
Kim, MR2
Kim, YE2
Hwang, JH2
Kim, IK1
Song, SW1
Kim, JW2
Lee, WW2
Kim, HJ2
Kim, C2
Kim, HC2
Kim, IY2
Park, HP1
Kim, DG2
Jeon, BS1
Paek, SH2
Romuk, E2
Szczurek, W2
Nowak, P2
Kwiecień, I1
Stolecka, D1
Birkner, E2
Xu, XP1
Yu, XY1
Wu, X1
Hu, XW1
Chen, JC1
Li, JB1
Wang, JF1
Deng, XM1
Ehm, G1
Yang, HJ1
Park, HR1
Lee, JM1
Park, E1
Jeon, B1
Castrioto, A1
Marmor, O1
Deffains, M1
Willner, D1
Linetsky, E1
Eitan, R1
Arkadir, D1
Skowron, M1
Prudel, B1
Hudziec, E1
Chwalińska, E1
Schneemilch, C1
Zaidel, A1
Nakajima, R1
Kato, J1
Iwasaki, K1
Ogawa, Y1
Gokan, D1
Ogawa, S1
Fábregas, N2
Rapado, J1
Gambús, PL1
Valero, R2
Carrero, E2
Salvador, L2
Nalda-Felipe, MA1
Hutchison, WD1
Lang, AE1
Dostrovsky, JO1
Lozano, AM1
Santos, P1
Arguis, MJ1
Rumià, J1
Valldeoriola, F1
Deogaonkar, A1
Deogaonkar, M1
Lee, JY1
Ebrahim, Z1
Schubert, A1
Dagtekin, O1
Berlet, T1
Gerbershagen, HJ1
Dueck, M1
Giesecke, T1
Velly, LJ1
Rey, MF1
Bruder, NJ1
Gouvitsos, FA1
Witjas, T1
Regis, JM1
Peragut, JC1
Gouin, FM1
Sonkajärvi, E1
Puumala, P1
Erola, T1
Baer, GA1
Karvonen, E1
Suominen, K1
Jäntti, V1
Anderson, BJ1
Marks, PV1
Futter, ME1
Krauss, JK1
Akeyson, EW1
Giam, P1
Jankovic, J1
Dewey, CC1
Chodakiewitz, JW1
Furuya, R1
Hirai, A1
Andoh, T1
Kudoh, I1
Okumura, F1
Fukuda, M2
Kameyama, S2
Kawaguchi, T1
Yamashita, S1
Tanaka, R2
Klostermann, F1
Funk, T1
Vesper, J1
Siedenberg, R1
Curio, G1
Murata, J1
Sawamura, Y1
Kitagawa, M1
Saito, H1
Kikuchi, S1
Tashiro, K1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00588926]20 participants (Actual)InterventionalActive, not recruiting
Changes of the Neuronal Activity in the Subthalamic Nucleus Under Propofol Sedation During Stereotactic Electrode Implantation.[NCT00355927]20 participants (Anticipated)Interventional2006-09-30Enrolling by invitation
[NCT01998204]62 participants (Actual)Observational2012-01-31Completed
Effects of Dexmedetomidine vs Propofol on the Recordings of Deep Brain Activity (Local Field Potentials) Measured Through Implanted Stimulators[NCT02256319]Phase 412 participants (Actual)Interventional2014-09-30Completed
Effects of Anesthesia Drugs on Neuronal Activity in the Basal Ganglia and Thalamus During Deep Brain Stimulation Electrode Implantation Surgery[NCT03283150]Phase 420 participants (Actual)Interventional2017-12-01Terminated (stopped due to Due to a decrease in scheduled study-eligible patients, we terminated the study prematurely)
Effectiveness and Reliability of Hypnosis in Stereotaxy[NCT03074422]22 participants (Anticipated)Interventional2017-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean Time in Minutes From Sedation to Recovery

This outocme meadsures the mean time from sedation to recovery. (NCT03283150)
Timeframe: up to 57 minutes

Interventionminutes (Mean)
Remifentanil29.43

Number of Individuals Examined for Neuronal Activity Changes at Multiple Brain Regions Under the Effect of Different Sedative Drugs

The number of subjects examining the neuronal activity changes at multiple brain regions under the effect of different sedation drugs to enable further study of the effects of anesthetics on brain regions and the mechanisms underlying loss of consciousness. (NCT03283150)
Timeframe: 1hrs 30 min

InterventionParticipants (Count of Participants)
Remifentanil14
Propofol0
Dexmedetomidine0

Sedatives Drugs Effects - Percent Change in Root Mean Square (RMS) of Electrical Activity

"Effects of propofol, remifentanil and dexmedetomidine on the neuronal activity during microelectrode recording (MER) in different brain structures that are used as target for DBS implantation will be measure.~The RMS of the electrical activity as a measure of the spiking rate of neurons in the vicinity of the electrode tip. normalize the RMS to the baseline value recorded at the first 2-5 minutes of MER (before entering the target area) to compensate for differences between patients and recording electrodes. In order to calculate the change in the normalized RMS following sedation the investigators will compare the mean RMS during 2 minutes of the stable recording of the pre-sedation baseline to the mean RMS during stable sedation and following recovery." (NCT03283150)
Timeframe: 45 minutes

Interventionpercent change (Mean)
Remifentanil2.69

Trials

5 trials available for propofol and Idiopathic Parkinson Disease

ArticleYear
Remifentanil requirement for i-gel insertion is reduced in male patients with Parkinson's disease undergoing deep brain stimulator implantation: an up-and-down sequential allocation trial.
    BMC anesthesiology, 2022, 06-24, Volume: 22, Issue:1

    Topics: Adult; Anesthetics, Intravenous; Brain; Humans; Male; Middle Aged; Parkinson Disease; Piperidines; P

2022
Minimum Alveolar Concentration-Awake of Sevoflurane is Decreased in Patients with Parkinson's Disease: An Up-and-Down Sequential Allocation Trial.
    Clinical interventions in aging, 2021, Volume: 16

    Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics; Anesthetics, Inhalation; Dose-Response Relation

2021
Propofol requirement for induction of unconsciousness is reduced in patients with Parkinson's disease: a case control study.
    BioMed research international, 2015, Volume: 2015

    Topics: Anesthetics, General; Case-Control Studies; Consciousness; Dose-Response Relationship, Drug; Drug Ad

2015
Differential dynamic of action on cortical and subcortical structures of anesthetic agents during induction of anesthesia.
    Anesthesiology, 2007, Volume: 107, Issue:2

    Topics: Aged; Anesthesia; Anesthetics; Cerebral Cortex; Consciousness; Deep Brain Stimulation; Dose-Response

2007
Thalamic potentials evoked by motor point stimulation.
    Muscle & nerve, 2000, Volume: 23, Issue:2

    Topics: Aged; Anesthetics, Intravenous; Cerebral Palsy; Electric Stimulation; Evoked Potentials; Female; Hum

2000

Other Studies

32 other studies available for propofol and Idiopathic Parkinson Disease

ArticleYear
Propofol Withdrawal Dyskinesia in a Parkinson's Disease Patient with Levodopa-Induced Dyskinesia.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2023, Volume: 50, Issue:2

    Topics: Antiparkinson Agents; Dyskinesias; Humans; Levodopa; Parkinson Disease; Propofol

2023
Acute psychosis following propofol in a patient with Parkinson disease: Effects of a γ-aminobutyric acid-dopamine imbalance.
    Psychiatry and clinical neurosciences, 2022, Volume: 76, Issue:6

    Topics: Anesthetics, Intravenous; Dopamine; gamma-Aminobutyric Acid; Humans; Parkinson Disease; Propofol; Ps

2022
Asleep DBS under ketamine sedation: Proof of concept.
    Neurobiology of disease, 2022, Volume: 170

    Topics: Anesthesia, General; Brain Neoplasms; Deep Brain Stimulation; Humans; Ketamine; Microelectrodes; Par

2022
Comparison of Half-Effective Concentration of Propofol in Patients with Parkinson's Disease and Non-Parkinson's Disease.
    Clinical interventions in aging, 2023, Volume: 18

    Topics: Humans; Meningeal Neoplasms; Meningioma; Parkinson Disease; Propofol; Prospective Studies

2023
Dynamic changes in rhythmic and arrhythmic neural signatures in the subthalamic nucleus induced by anaesthesia and tracheal intubation.
    British journal of anaesthesia, 2020, Volume: 125, Issue:1

    Topics: Anesthesia, General; Anesthetics, Intravenous; Deep Brain Stimulation; Electroencephalography; Femal

2020
Sedative drugs modulate the neuronal activity in the subthalamic nucleus of parkinsonian patients.
    Scientific reports, 2020, 09-03, Volume: 10, Issue:1

    Topics: Adult; Aged; Deep Brain Stimulation; Female; Humans; Hypnotics and Sedatives; Male; Microelectrodes;

2020
Sedative drugs modulate the neuronal activity in the subthalamic nucleus of parkinsonian patients.
    Scientific reports, 2020, 09-03, Volume: 10, Issue:1

    Topics: Adult; Aged; Deep Brain Stimulation; Female; Humans; Hypnotics and Sedatives; Male; Microelectrodes;

2020
Sedative drugs modulate the neuronal activity in the subthalamic nucleus of parkinsonian patients.
    Scientific reports, 2020, 09-03, Volume: 10, Issue:1

    Topics: Adult; Aged; Deep Brain Stimulation; Female; Humans; Hypnotics and Sedatives; Male; Microelectrodes;

2020
Sedative drugs modulate the neuronal activity in the subthalamic nucleus of parkinsonian patients.
    Scientific reports, 2020, 09-03, Volume: 10, Issue:1

    Topics: Adult; Aged; Deep Brain Stimulation; Female; Humans; Hypnotics and Sedatives; Male; Microelectrodes;

2020
Effect of Dexmedetomidine and Propofol on Basal Ganglia Activity in Parkinson Disease: A Controlled Clinical Trial.
    Anesthesiology, 2017, Volume: 126, Issue:6

    Topics: Action Potentials; Aged; Basal Ganglia; Deep Brain Stimulation; Dexmedetomidine; Female; Humans; Hyp

2017
Propofol-induced Changes in α-β Sensorimotor Cortical Connectivity.
    Anesthesiology, 2018, Volume: 128, Issue:2

    Topics: Aged; Anesthetics, Intravenous; Deep Brain Stimulation; Electroencephalography; Essential Tremor; Fe

2018
Single unit activity of subthalamic nucleus of patients with Parkinson's disease under local and generalized anaesthesia: Multifactor analysis.
    Neuroscience research, 2019, Volume: 145

    Topics: Aged; Anesthesia, General; Anesthesia, Local; Deep Brain Stimulation; Electrodes, Implanted; Humans;

2019
Propofol Anesthesia Precludes LFP-Based Functional Mapping of Pallidum during DBS Implantation.
    Stereotactic and functional neurosurgery, 2018, Volume: 96, Issue:4

    Topics: Aged; Anesthesia; Anesthetics, Intravenous; Brain Mapping; Deep Brain Stimulation; Female; Globus Pa

2018
Influence of propofol and fentanyl on deep brain stimulation of the subthalamic nucleus.
    Journal of Korean medical science, 2014, Volume: 29, Issue:9

    Topics: Aged; Anesthetics, Intravenous; Deep Brain Stimulation; Electrodes, Implanted; Female; Fentanyl; Hum

2014
Influence of propofol on oxidative-antioxidative system parameters in peripheral organs of rats with Parkinson disease.
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Jun-12, Volume: 69

    Topics: Animals; Antioxidants; Heart; Kidney; Liver; Lung; Male; Oxidation-Reduction; Parkinson Disease; Pro

2015
Bilateral Deep Brain Stimulation of the Subthalamic Nucleus under Sedation with Propofol and Fentanyl.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Activities of Daily Living; Aged; Anesthetics, Intravenous; Deep Brain Stimulation; Electrodes, Impl

2016
Anesthesia reduces discharge rates in the human pallidum without changing the discharge rate ratio between pallidal segments.
    The European journal of neuroscience, 2016, Volume: 44, Issue:11

    Topics: Action Potentials; Adult; Anesthetics, Intravenous; Case-Control Studies; Deep Brain Stimulation; Dy

2016
Effects of Propofol on Oxidative Stress Parameters in Selected Parts of the Brain in a Rat Model of Parkinson Disease.
    Postepy higieny i medycyny doswiadczalnej (Online), 2016, Dec-31, Volume: 70, Issue:0

    Topics: Animals; Antioxidants; Brain; Disease Models, Animal; Hypnotics and Sedatives; Male; Oxidative Stres

2016
[General anaesthesia for neurological diseases].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2010, Volume: 45, Issue:5

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Autonomic Nervous System; Br

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
Propofol decreases neuronal population spiking activity in the subthalamic nucleus of Parkinsonian patients.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Consciousness Monitors; Deep Brain Stimulation; Drug Ad

2010
[Effects of the induction of anesthesia with propofol on hemodynamics in patients with Parkinson's disease].
    Masui. The Japanese journal of anesthesiology, 2011, Volume: 60, Issue:10

    Topics: Aged; Anesthesia, General; Autonomic Pathways; Deep Brain Stimulation; Female; Fentanyl; Hemodynamic

2011
Modeling of the sedative and airway obstruction effects of propofol in patients with Parkinson disease undergoing stereotactic surgery.
    Anesthesiology, 2002, Volume: 97, Issue:6

    Topics: Adult; Aged; Airway Obstruction; Anesthetics, Intravenous; Conscious Sedation; Female; Humans; Male;

2002
Pallidal neuronal activity: implications for models of dystonia.
    Annals of neurology, 2003, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Child; Dystonia; Electromyography; Globus Pallidus; Humans; Micr

2003
[Preoperative adverse events during stereotactic microelectrode-guided deep brain surgery in Parkinson's disease].
    Revista espanola de anestesiologia y reanimacion, 2004, Volume: 51, Issue:9

    Topics: Aged; Anesthetics, General; Cardiovascular Diseases; Consciousness Disorders; Deep Brain Stimulation

2004
Propofol-induced dyskinesias controlled with dexmedetomidine during deep brain stimulation surgery.
    Anesthesiology, 2006, Volume: 104, Issue:6

    Topics: Deep Brain Stimulation; Dexmedetomidine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans;

2006
Anesthesia and deep brain stimulation: postoperative akinetic state after replacement of impulse generators.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Aged; Analgesics, Opioid; Anesthesia; Anesthesia, General; Anesthetics, Intravenous; Coma; Deep Brai

2006
Burst suppression during propofol anaesthesia recorded from scalp and subthalamic electrodes: report of three cases.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:2

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Electrodes, Implanted; Electroencephalography;

2008
Propofol--contrasting effects in movement disorders.
    British journal of neurosurgery, 1994, Volume: 8, Issue:3

    Topics: Anesthesia, Intravenous; Humans; Intracranial Aneurysm; Male; Middle Aged; Neurologic Examination; P

1994
Propofol-induced dyskinesias in Parkinson's disease.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:2

    Topics: Aged; Conscious Sedation; Dyskinesia, Drug-Induced; Female; Globus Pallidus; Humans; Hypnotics and S

1996
Use of propofol in patients with Parkinson's disease: report of a case.
    CRNA : the clinical forum for nurse anesthetists, 1997, Volume: 8, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Cataract Extraction; Humans; Male; Parkinson Disease; Propofol

1997
Localizing pallidotomy lesions.
    Journal of neurosurgery, 1998, Volume: 88, Issue:6

    Topics: Anesthetics, Intravenous; Electric Stimulation; Electroencephalography; Globus Pallidus; Humans; Mag

1998
Successful perioperative management of a patient with Parkinson's disease by enteral levodopa administration under propofol anesthesia.
    Anesthesiology, 1998, Volume: 89, Issue:1

    Topics: Aged; Anesthetics, Intravenous; Anesthetics, Local; Antiparkinson Agents; Bupivacaine; Colonic Neopl

1998
[Stereotaxy during intravenous anesthesia with propofol].
    No shinkei geka. Neurological surgery, 1998, Volume: 26, Issue:8

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain; Cerebral Palsy; Female; Human

1998
Propofol narcosis dissociates human intrathalamic and cortical high-frequency (> 400 hz) SEP components.
    Neuroreport, 2000, Aug-03, Volume: 11, Issue:11

    Topics: Action Potentials; Aged; Anesthetics, Intravenous; Cerebral Cortex; Electric Stimulation Therapy; El

2000
[Minimally invasive stereotactic functional surgery using an intravenous anesthetic propofol and applying Image Fusion and AtlasPlan].
    No to shinkei = Brain and nerve, 2001, Volume: 53, Issue:5

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Brain; Humans; Image Processing, Computer-Assiste

2001