propofol has been researched along with Hypoventilation in 13 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Hypoventilation: A reduction in the amount of air entering the pulmonary alveoli.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to estimate the effective concentration of remifentanil in 95% of patients (EC95) for the prevention of emergence cough after LMS under propofol anesthesia using the biased coin design (BCD) up-down method." | 9.27 | Predicting effective remifentanil concentration in 95% of patients to prevent emergence cough after laryngomicroscopic surgery. ( Ahn, SH; Kim, HY; Kim, JY; Kwak, HJ; Lee, SY; Park, HY, 2018) |
| "The primary objective of this investigation was to examine the effect of ketamine on hypoventilation in patients receiving deep sedation for surgery with midazolam and propofol." | 9.19 | The effect of ketamine on hypoventilation during deep sedation with midazolam and propofol: a randomised, double-blind, placebo-controlled trial. ( Ahmad, S; De Oliveira, GS; Fitzgerald, PC; Hansen, N; McCarthy, RJ, 2014) |
| " The purpose of this study was to estimate the effective concentration of remifentanil in 95% of patients (EC95) for the prevention of emergence cough after LMS under propofol anesthesia using the biased coin design (BCD) up-down method." | 5.27 | Predicting effective remifentanil concentration in 95% of patients to prevent emergence cough after laryngomicroscopic surgery. ( Ahn, SH; Kim, HY; Kim, JY; Kwak, HJ; Lee, SY; Park, HY, 2018) |
| " The primary outcome was the occurrence of a respiratory adverse event (desaturation, apnea, or hypoventilation) requiring an intervention by the sedating physician." | 5.22 | Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial. ( Bell, A; Ding, M; Ferguson, I; Holdgate, A; New, L; Treston, G, 2016) |
| "To characterize the profiles of alveolar hypoventilation during colonoscopies performed under sedoanalgesia with a combination of alfentanil and either midazolam or propofol." | 5.16 | Carbon dioxide accumulation during analgosedated colonoscopy: comparison of propofol and midazolam. ( Beglinger, C; Heuss, LT; Sugandha, SP, 2012) |
| " Episodes of apnea or hypoventilation detected by capnography were compared with the occurrence of hypoxemia." | 5.14 | Capnography is superior to pulse oximetry for the detection of respiratory depression during colonoscopy. ( Barbado, A; Cacho, G; Fernández-Rodríguez, CM; Lledó, JL; Ojea, R; Pérez-Calle, JL, 2010) |
| " Providers of all sedation types should be aware of hypotension, apnea, hypoventilation, and hypoxia that can develop and they should be able to manage the patient under these circumstances." | 5.01 | Moderate and deep sedation training and pharmacology for nonanesthesiologists: recommendations for effective practice. ( Beutler, SS; Tran, TT; Urman, RD, 2019) |
| "Fentanyl was continued at the designated rate through the initial postoperative phase." | 2.71 | Effect-site concentration of propofol for recovery of consciousness is virtually independent of fentanyl effect-site concentration. ( Iwakiri, H; Matsukawa, T; Nagata, O; Ozaki, M; Sessler, DI, 2003) |
| "High midazolam dose was associated with lower IPI levels during the procedure." | 1.42 | The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children. ( Adiv, OE; Garah, J; Rosen, I; Shaoul, R, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 11 (84.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leslie, K | 1 |
| Sgroi, J | 1 |
| Kim, HY | 1 |
| Kim, JY | 1 |
| Ahn, SH | 1 |
| Lee, SY | 1 |
| Park, HY | 1 |
| Kwak, HJ | 1 |
| Boriosi, JP | 1 |
| Zhao, Q | 1 |
| Preston, A | 1 |
| Hollman, GA | 1 |
| Tran, TT | 1 |
| Beutler, SS | 1 |
| Urman, RD | 1 |
| De Oliveira, GS | 1 |
| Fitzgerald, PC | 1 |
| Hansen, N | 1 |
| Ahmad, S | 1 |
| McCarthy, RJ | 1 |
| Green, SM | 1 |
| Andolfatto, G | 1 |
| Callaham, ML | 1 |
| Garah, J | 1 |
| Adiv, OE | 1 |
| Rosen, I | 1 |
| Shaoul, R | 1 |
| Ferguson, I | 1 |
| Bell, A | 1 |
| Treston, G | 1 |
| New, L | 1 |
| Ding, M | 1 |
| Holdgate, A | 1 |
| Cacho, G | 1 |
| Pérez-Calle, JL | 1 |
| Barbado, A | 1 |
| Lledó, JL | 1 |
| Ojea, R | 1 |
| Fernández-Rodríguez, CM | 1 |
| Heuss, LT | 1 |
| Sugandha, SP | 1 |
| Beglinger, C | 1 |
| Iwakiri, H | 1 |
| Nagata, O | 1 |
| Matsukawa, T | 1 |
| Ozaki, M | 1 |
| Sessler, DI | 1 |
| Haberer, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Ketamine in The Prevention of Hypoventilation in Patients With and Without a Positive Berlin Questionnaire Undergoing Deep Sedation[NCT01535976] | 54 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Bronchoscopy Procedures Under Sedation[NCT05137587] | 60 participants (Actual) | Interventional | 2022-09-01 | Completed | |||
| Comparison of Efficacy and Safety of the Postoperative Analgesia Methods for Supratentorial Craniotomy by Integrated Pulmonary Index (IPI)[NCT02929147] | Phase 4 | 90 participants (Anticipated) | Interventional | 2016-11-30 | Not yet recruiting | ||
| Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Endoscopy Procedures Under Sedation[NCT05137574] | 60 participants (Actual) | Interventional | 2021-05-10 | Completed | |||
| Prospective Observational Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio at the Emergency Department of a Tertiary Hospital[NCT04028141] | 61 participants (Actual) | Observational | 2018-02-01 | Completed | |||
| Intravenous Sedation and Analgesia Using Propofol, Fentanyl and Ketamine (PFK) Versus General Anesthesia in Minor Urological Procedures.[NCT04285528] | 200 participants (Actual) | Interventional | 2019-04-17 | Completed | |||
| [NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
| Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Subjects receiving intraoperative ketamine in addition to propofol will demonstrate less hypoventilation during the surgical procedure. (NCT01535976)
Timeframe: 8 hours
| Intervention | % time (Median) |
|---|---|
| Ketamine | 1.2 |
| Placebo | 65 |
3 reviews available for propofol and Hypoventilation
| Article | Year |
|---|---|
Sedation for gastrointestinal endoscopy in Australia: what is the same and what is different?
Topics: Airway Management; Anesthesia; Australia; Conscious Sedation; Deep Sedation; Endoscopy, Gastrointest | 2018 |
Moderate and deep sedation training and pharmacology for nonanesthesiologists: recommendations for effective practice.
Topics: Administration, Intravenous; Analgesics, Opioid; Anesthesiology; Apnea; Benzodiazepines; Conscious S | 2019 |
Managing propofol-induced hypoventilation.
Topics: Airway Management; Capnography; Humans; Hypnotics and Sedatives; Hypoventilation; Propofol | 2015 |
6 trials available for propofol and Hypoventilation
| Article | Year |
|---|---|
Predicting effective remifentanil concentration in 95% of patients to prevent emergence cough after laryngomicroscopic surgery.
Topics: Adult; Airway Extubation; Anesthesia; Anesthesia Recovery Period; Anesthetics, Intravenous; Cough; D | 2018 |
The effect of ketamine on hypoventilation during deep sedation with midazolam and propofol: a randomised, double-blind, placebo-controlled trial.
Topics: Adult; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Hypoventilation; Ketamine; Mida | 2014 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Capnography is superior to pulse oximetry for the detection of respiratory depression during colonoscopy.
Topics: Adult; Aged; Apnea; Capnography; Carbon Dioxide; Colonoscopy; Computer Systems; Conscious Sedation; | 2010 |
Carbon dioxide accumulation during analgosedated colonoscopy: comparison of propofol and midazolam.
Topics: Aged; Alfentanil; Analgesics, Opioid; Biomarkers; Blood Gas Monitoring, Transcutaneous; Carbon Dioxi | 2012 |
Effect-site concentration of propofol for recovery of consciousness is virtually independent of fentanyl effect-site concentration.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Atropine; Bradycardia; Female; Fentanyl | 2003 |
4 other studies available for propofol and Hypoventilation
| Article | Year |
|---|---|
The utility of the pretracheal stethoscope in detecting ventilatory abnormalities during propofol sedation in children.
Topics: Adolescent; Anesthesia; Auscultation; Capnography; Child; Child, Preschool; Deep Sedation; Female; H | 2019 |
Expert opinion: supplementing the gaps in evidence-based medicine.
Topics: Humans; Hypnotics and Sedatives; Hypoventilation; Propofol | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se | 2015 |
[Premedication and sedation complications during ophthalmic anesthesia].
Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anesthesi | 2000 |