propofol has been researched along with Hypotension in 291 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
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" This study aimed to compare the efficacy of isoflurane-remifentanil (I-R) versus propofol-remifentanil (P-R) to induce controlled hypotension and to assess surgeon satisfaction with each of these combinations during rhinoplasty." | 9.69 | Efficacy of Isoflurane-Remifentanil versus Propofol-Remifentanil on Controlled Hypotension and Surgeon Satisfaction in Rhinoplasty: A Single-Blind Clinical Trial Study. ( Abbasi, R; Abbasi, S; Dehghanpisheh, L; Kaboodkhani, R; Khademi, S; Rafati, Z; Sahmeddini, MA; Samadi, K, 2023) |
"BACKGROUND This prospective, randomized, controlled study evaluated the efficacy and safety of remimazolam tosilate sedation with adjuvant sufentanil, relative to propofol, for Chinese patients with liver cirrhosis undergoing gastroscopy." | 9.51 | Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study. ( Cao, Y; Chi, P; Lv, W; Quan, Z; Xue, FS; Zhou, C, 2022) |
" Therefore, the present study sought to evaluate the effect of different doses of esketamine compared with the effect of fentanyl on incidence of perioperative hypotension in patients undergoing painless abortion surgery and to explore the optimal esketamine dose for this population." | 9.51 | Effect of different doses of esketamine compared with fentanyl combined with propofol on hypotension in patients undergoing painless abortion surgery: a prospective, randomized, double-blind controlled clinical trial. ( Chen, J; Hu, B; Shen, M; Wang, F; Yang, Y; Zhou, Q; Zou, X, 2022) |
"In geriatric patients, hypotension is often reported after general anesthesia induction using propofol." | 9.51 | Hypotension after general anesthesia induction using remimazolam in geriatric patients: Protocol for a double-blind randomized controlled trial. ( Goto, T; Masui, K; Mihara, T; Saigusa, Y; Takaki, R; Yamamoto, N; Yokose, M, 2022) |
"Hypotension is common during propofol sedation for colonoscopy and of a magnitude and duration associated with harm in surgical patients." | 9.22 | Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis. ( Absalom, AR; Barends, CRM; Jones, JB; Sneyd, JR, 2022) |
"Phenylephrine 200mcg is more effective than 100mcg in attenuating propofol induced hypotension, especially during the first two minutes after induction, in patients aged 55 years and above." | 9.22 | The effect of prophylactic phenylephrine on systemic hypotension during induction of anaesthesia with propofol in patients over 55 years old. ( Kwok, FY; Venugobal, S, 2016) |
"Propofol is commonly used in pediatric sedation, which may cause hypotension during induction." | 9.20 | A presedation fluid bolus does not decrease the incidence of propofol-induced hypotension in pediatric patients. ( Aldag, JC; Deshpande, GG; Jager, MD, 2015) |
"The utilization of phenylephrine to correct hypotension induced by anesthesia has a negative impact on S(c)O(2) while ephedrine maintains frontal lobe oxygenation potentially related to an increase in CO." | 9.14 | Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia-induced hypotension. ( Brassard, P; Jørgensen, TB; Nissen, P; Secher, NH, 2010) |
"This study was conducted to examine whether pretreatment with intravenous atropine could prevent bradycardia and hypotension during induction of total intravenous anesthesia with propofol and remifentanil in a prospective randomized placebo-controlled manner." | 9.14 | Can intravenous atropine prevent bradycardia and hypotension during induction of total intravenous anesthesia with propofol and remifentanil? ( Ariyama, J; Hayashida, M; Kitamura, A; Maruyama, K; Nakagawa, H; Nishikawa, Y, 2010) |
"The present study compared the efficacy of preloading with colloid "Haemaccel" with vasoconstrictor (intravenous ephedrine sulphate) in preventing hypotension during propofol induction." | 9.13 | Prevention of hypotension during propofol induction: a comparison of preloading with 3.5% polymers of degraded gelatin (Haemaccel) and intravenous ephedrine. ( Bhadani, UK; Bhattarai, BK; Biswas, BK; Dhungana, Y; Tripathi, M, 2008) |
"Propofol produces anaesthesia with rapid recovery but also causes pain or discomfort on injection." | 9.13 | Prevention of propofol-induced injection pain by sufentanil: a placebo-controlled comparison with remifentanil. ( Honarmand, A; Safavi, M, 2008) |
"Propofol is twice as likely as etomidate to evoke hypotension in anaesthesia induction of patients with severe aortic stenosis; however, etomidate transiently decreases post-operative serum cortisol concentrations." | 9.12 | Propofol causes more hypotension than etomidate in patients with severe aortic stenosis: a double-blind, randomized study comparing propofol and etomidate. ( Bendel, S; Pölönen, P; Ruokonen, E; Uusaro, A, 2007) |
"Phenylephrine in doses of 100 micrograms effectively attenuates anticipated hypotension upon induction of general anaesthesia with propofol." | 9.12 | Attenuation of hypotension using phenylephrine during induction of anaesthesia with propofol. ( Imran, M; Khan, FH; Khan, MA, 2007) |
"This prospective, randomized, double-blinded study was designed to compare the effects of desflurane, isoflurane and sevoflurane when combined with remifentanil for induced hypotension on surgical conditions and operative field during tympanoplasty." | 9.11 | Induced hypotension for tympanoplasty: a comparison of desflurane, isoflurane and sevoflurane. ( Aypar, U; Başgül, E; Celiker, V; Dal, D; Ozer, E; Salman, MA, 2004) |
"This prospective, double-blind, randomized, placebo-controlled study compares the effects of ephedrine and ketamine on injection pain, and hypotension from propofol." | 9.11 | Comparison of ephedrine and ketamine in prevention of injection pain and hypotension due to propofol induction. ( Altunkaya, H; Ayoğlu, H; Ciçek, E; Demirel, CB; Ozer, Y; Ozkoçak, I, 2005) |
"In patients chronically treated with angiotensin converting-enzyme inhibitors (ACEI), typically selected doses of ephedrine do not always restore arterial blood pressure when anesthesia-induced hypotension occurs." | 9.10 | Terlipressin-ephedrine versus ephedrine to treat hypotension at the induction of anesthesia in patients chronically treated with angiotensin converting-enzyme inhibitors: a prospective, randomized, double-blinded, crossover study. ( Bertrand, M; Brun, L; Coriat, P; Gourdin, M; Meersschaert, K; Mouren, S; Riou, B, 2002) |
"Nicardipine-, nitroglycerin-, and prostaglandin E1-induced hypotension attenuate the human cerebrovascular CO2 reactivity during propofol-fentanyl anesthesia." | 9.09 | Effects of nicardipine-, nitroglycerin-, and prostaglandin E1-induced hypotension on human cerebrovascular carbon dioxide reactivity during propofol-fentanyl anesthesia. ( Endoh, H; Honda, T; Komura, N; Shibue, C; Shimoji, K; Watanabe, I, 1999) |
"We conducted a double-blind, randomised, placebo-controlled study evaluating the efficacy of prophylactic metaraminol for preventing propofol-induced hypotension." | 9.09 | The effect of prophylactic metaraminol on systemic hypotension caused by induction of anaesthesia with propofol in patients over 55 years old. ( Chiu, CL; Tew, GP; Wang, CY, 2001) |
"The objective of this study was to determine the effectiveness of two prophylactic approaches against the anticipated hypotension induced by propofol during rapid-sequence intubation." | 9.08 | Prophylaxis against the systemic hypotension induced by propofol during rapid-sequence intubation. ( el-Beheiry, H; Kim, J; Milne, B; Seegobin, R, 1995) |
"We compared propofol with high-dose barbiturates in the treatment of refractory status epilepticus (RSE) and propose a protocol for the administration of propofol in RSE in adults, correlating propofol's effect with plasma levels." | 9.08 | Treatment of refractory status epilepticus with propofol: clinical and pharmacokinetic findings. ( Dulaney, E; Kramer, TH; O'Meeghan, R; Raps, EC; Skaar, DJ; Stecker, MM, 1998) |
"The present investigation explored the possibility that the commonly observed hypotension that occurs during induction of anesthesia with propofol might be related to its ability to produce venodilation." | 9.07 | Venodilation contributes to propofol-mediated hypotension in humans. ( Berens, RA; Ebert, TJ; Kampine, JP; Muzi, M, 1992) |
"These findings suggest that 5-ALA-HCl does not affect the antihypertensive agents-induced hypotensive effect, but enhances the bupivacaine-induced hypotensive effect, especially in SHRs, indicating that 5-ALA may contribute to anesthesia-induced hypotension via suppression of sympathetic nerve activity in patients with hypertension." | 8.31 | 5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. ( Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N, 2023) |
"In this study, the aim was to research the effects of smoking habits on controlled hypotension administered with nitroglycerin during ear-nose-throat surgery." | 8.31 | Effects of smoking on controlled hypotension with nitroglycerin during ear-nose-throat surgery. ( Ersoy, A; Sinoglu, B, 2023) |
"The primary exposure was total propofol induction dose in mg/kg, and the primary outcome was occurrence of severe hypotension (MAP≤55 mmHg) prior to surgical incision, stratified by non-invasive vs." | 8.12 | Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65. ( Akhtar, S; Bardia, A; Burg, MM; Dai, F; Kheterpal, S; Mathis, M; Michel, G; Schonberger, RB; Shah, N; Vaughn, MT, 2022) |
"Although the largest decrease in propofol dosage required for intubation was after IV premedication with acepromazine and butorphanol, hypotension and apnea still occurred." | 8.12 | Effects of intravenous acepromazine and butorphanol on propofol dosage for induction of anesthesia in healthy Beagle dogs. ( Dantino, SC; Kleine, SA; Seddighi, R; Smith, CK; Smith, SM; Zhu, X, 2022) |
"The development of hypotension on administration of intravenous propofol is common and independently associated with adverse outcomes." | 8.02 | Predicting hypotension during anesthesia: Variation in pulse oximetry plethysmography predicts propofol-induced hypotension in children. ( Choi, SN; Jang, YE; Ji, SH; Kim, EH; Kim, HS; Kim, JT; Lee, JH, 2021) |
" This report describes a case of severe bradyarrhythmia during anesthetic induction with propofol, midazolam, sufentanil, and vecuronium." | 8.02 | Bradyarrhythmia and hypotension during anesthetic induction-reconsideration of nifedipine: a case report. ( Zhang, X, 2021) |
" We hypothesised that anaesthesia-induced hypotension causes renal vasoconstriction and decreased oxygen delivery via angiotensin II-mediated renal vasoconstriction." | 7.96 | Pre-treatment with the angiotensin receptor 1 blocker losartan protects renal blood flow and oxygen delivery after propofol-induced hypotension in pigs. ( Franzén, S; Frithiof, R, 2020) |
"In early 2015, clinicians throughout Zambia noted a range of unpredictable adverse events after the administration of propofol, including urticaria, bronchospasm, profound hypotension, and most predictably an inadequate depth of anesthesia." | 7.85 | An Analysis of Substandard Propofol Detected in Use in Zambian Anesthesia. ( Attaran, A; Bould, MD; Curtis, S; Mayer, P; Mumphansha, H; Nickerson, JW; Overton, S, 2017) |
"Hypotension is a common side effect of propofol, but there are no reliable methods to determine which patients are at risk for significant propofol-induced hypotension (PIH)." | 7.83 | Ultrasound measurement of inferior vena cava collapse predicts propofol-induced hypotension. ( Au, AK; Fields, JM; Ku, BS; Papanagnou, D; Shirazi, M; Steinberg, D; Thom, C, 2016) |
"A multicenter, retrospective, propensity-matched pilot study was conducted comparing patients with sepsis or severe sepsis who received CIV propofol for sedation to those who did not." | 7.83 | Effects of propofol on vasopressor use in patients with sepsis and severe sepsis: A pilot study. ( Boucher, AN; Jones, GM; Kimmons, LA; Marler, J; Mohrien, K; Oliphant, CS; Vandigo, JE, 2016) |
"Hypotension was the most frequent anesthetic complication during procedure under propofol-based deep sedation, but this method was safe and effective under appropriate monitoring." | 7.81 | Age correlates with hypotension during propofol-based anesthesia for endoscopic retrograde cholangiopancreatography. ( Khoi, CS; Lin, TY; Lu, CW; Wang, HC; Wong, JJ, 2015) |
" Univariate analyses were performed to determine risk factors associated with severe hypotension during sedation with propofol." | 7.80 | Predictors of severe hypotension in neurocritical care patients sedated with propofol. ( Doepker, BA; Elijovich, L; Erdman, MJ; Jones, GM; Kimmons, LA, 2014) |
" We report a case of profound hypotension after anesthesia induction with propofol in a patient who was treated with two 600 mg doses of rifampin for prophylaxis of infection before surgery." | 7.79 | Case report: profound hypotension after anesthetic induction with propofol in patients treated with rifampin. ( Ehrenfeld, JM; Jiang, Y; Mirzakhani, H; Nozari, A; Peterfreund, R; Rosow, C; Sandberg, W; Szabo, M; Walsh, JL; Wang, J, 2013) |
"Although obesity was associated with an increased frequency of SRCs, propofol sedation can be used safely in obese patients undergoing AEPs when administered by trained professionals." | 7.77 | Obesity as a risk factor for sedation-related complications during propofol-mediated sedation for advanced endoscopic procedures. ( Azar, R; Cote, GA; Early, D; Edmundowicz, SA; Hall, M; Hovis, CE; Hovis, RM; Jonnalagadda, SS; Kushnir, V; Mullady, DK; Murad, F; Waldbaum, L; Wani, S, 2011) |
" Propofol generally offered good intubating conditions, but we encountered severe problems with arterial hypotension." | 7.76 | Propofol as an induction agent for endotracheal intubation can cause significant arterial hypotension in preterm neonates. ( Eifinger, F; Huenseler, C; Kribs, A; Oberthuer, A; Roth, B; Welzing, L, 2010) |
"The authors report a case of short-term high-dose propofol-related metabolic acidosis in a 3-year-old girl." | 7.74 | Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report. ( Muhonen, MG; Nwagwu, CI; Westhout, FD, 2007) |
"In two patients, pheochromocytoma resection was performed under propofol/fentanyl anesthesia, while bispectral index (BIS) monitoring and blood volume measurement using pulse spectrophotometry were done." | 7.73 | [Anesthetic management with propofol for pheochromocytoma resection under monitoring of bispectral index and blood volume]. ( Ishida, K; Matsumoto, M; Morimoto, Y; Orita, H; Sakabe, T; Tsuruta, S; Utada, K, 2006) |
" There had not been severe hypotension reported in the literature in consequence of inadvertent epidural thiopental administration." | 7.73 | Intravenous propofol precipitates the hypotension induced by inadvertent epidural thiopental injection. ( Chan, KH; Chang, WK; Chu, CC; Huang, SY; Wang, CC, 2006) |
"During incomplete cerebral ischemia, the neuroprotective anesthetics sevoflurane and propofol suppressed cerebral increases in norepinephrine and glutamate concentrations." | 7.72 | The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats. ( Blobner, M; Engelhard, K; Hoffman, WE; Kochs, E; Matthes, B; Werner, C, 2003) |
"Reducing hypotension is crucial as hypotension is the most common side effect of spinal anesthesia, and in older patients with various comorbidities, it can lead to fatality." | 7.30 | Norepinephrine prevents hypotension in older patients under spinal anesthesia with intravenous propofol sedation: a randomized controlled trial. ( Cho, J; Kim, H; Kim, HJ; Kim, KS; Koh, WU; Lee, S; Park, SW; Ro, YJ, 2023) |
"Propofol is a widely used anesthetic drug because of its minor complication and also its fast effect." | 6.77 | Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. ( Ayatollahi, V; Behdad, S; Kargar, S; Yavari, T, 2012) |
" The results of this trial suggest that a propofol-based anesthetic, when compared to an enflurane-based anesthetic requiring additional dosing of fentanyl and midazolam for CPB, can lead to a significant reduction in time to extubation after CABG surgery, without adverse hemodynamic effects, increased risk of myocardial ischemia or infarction." | 6.68 | Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery. ( Buckland, MR; Bujor, MA; Davis, BB; Hunt, JO; Langley, M; McRae, R; Moloney, JT; Myles, PS; Weeks, AM, 1997) |
"Propofol sedation has a similar risk of cardiopulmonary adverse events compared with traditional agents for gastrointestinal endoscopic procedures." | 6.55 | Similar Risk of Cardiopulmonary Adverse Events Between Propofol and Traditional Anesthesia for Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis. ( Garg, S; Issa, D; Lopez, R; Sanaka, MR; Vargo, JJ; Wadhwa, V, 2017) |
"Overall, propofol induced a significant incidence of relative hypotension (mean arterial pressure 20% below baseline, 45%), apnoea (71%) and haemoglobin desaturation (65%) at induction of anaesthesia, with a higher incidence of hypotension and apnoea in the P-CRI than P-TCI group (68% versus 21%, p = 0." | 5.69 | Comparison between continuous rate infusion and target-controlled infusion of propofol in dogs: a randomized clinical trial. ( Cuniberti, B; Hughes, JL; Huuskonen, V, 2023) |
" With the increasing dose of alfentanil, the morbidity of hypotension and bradycardia increased significantly (P = 0." | 5.69 | A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial. ( Guan, ZY; Wang, CM; Wang, LL; Zhang, J; Zhang, YW; Zhao, P, 2023) |
"Remimazolam confers a lower risk of hypotension than propofol." | 5.69 | Comparison of hemodynamics during induction of general anesthesia with remimazolam and target-controlled propofol in middle-aged and elderly patients: a single-center, randomized, controlled trial. ( Kakuta, N; Kawanishi, R; Kinoshita, M; Sakai, Y; Sekiguchi, R; Tanaka, K, 2023) |
"Lidocaine-based regimen for induction of anesthesia reduced the risk of postinduction hypotension in older patients compared to the fentanyl-based regimen." | 5.69 | Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial. ( Amin, SM; Arafa, AS; ElSayed, OS; Hasanin, A; Hassan, A; Khaled, D; Mostafa, M, 2023) |
"Hypotension is common after anesthesia induction with propofol and is associated with increased morbidity." | 5.69 | Hemodynamic effects of a low versus a high dose of propofol during induction of anesthesia. A randomized trial. ( Falk, RS; Hauge, TH; Langesaeter, E; Sjøen, GH; Tønnessen, TI, 2023) |
" This study aimed to compare the efficacy of isoflurane-remifentanil (I-R) versus propofol-remifentanil (P-R) to induce controlled hypotension and to assess surgeon satisfaction with each of these combinations during rhinoplasty." | 5.69 | Efficacy of Isoflurane-Remifentanil versus Propofol-Remifentanil on Controlled Hypotension and Surgeon Satisfaction in Rhinoplasty: A Single-Blind Clinical Trial Study. ( Abbasi, R; Abbasi, S; Dehghanpisheh, L; Kaboodkhani, R; Khademi, S; Rafati, Z; Sahmeddini, MA; Samadi, K, 2023) |
"Remimazolam induction was more stable than propofol induction in preserving normal hemodynamics and was associated with a relatively lower incidence of hypotension." | 5.69 | Comparison of remimazolam and propofol induction on hemodynamic response in hypertensive patients. ( Choi, EK; Jang, Y; Park, SJ, 2023) |
"Hypotension is the most common adverse event under propofol-mediated sedation and is possible to cause varying degrees of damage to patients." | 5.69 | The safety and efficacy of remimazolam tosylate combined with propofol in upper gastrointestinal endoscopy: A multicenter, randomized clinical trial. ( Deng, Y; Dou, Y; Li, D; Liu, X; Ma, S; Wang, X; Wei, A; Wu, J; Yang, M; Zhou, S, 2023) |
" Therefore, we aimed to evaluate the effect of ramosetron, a 5-HT3 antagonist, administered on hypotension at the induction of total intravenous anesthesia (TIVA) with propofol and remifentanil." | 5.69 | The preventive effect of 5-hydroxytryptamine-3 receptor antagonist on blood pressure reduction and postoperative nausea and vomiting during general anesthesia induction: A double-blinded, randomized controlled trial. ( Hong, SW; Kim, SH, 2023) |
"Propofol may result in hypotension, bradycardia and loss of protective reflexes, especially in elderly patients, while esketamine, a N-methyl-D-aspartate receptor antagonist, has analgesic, anaesthetic and sympathomimetic properties and is known to cause less cardiorespiratory depression." | 5.51 | The median effective concentration of propofol with different doses of esketamine during gastrointestinal endoscopy in elderly patients: A randomized controlled trial. ( Chen, HY; Ding, T; Liu, W; Song, JC; Yang, B; Yang, H; Zhao, Q, 2022) |
" Complications including apnea, hypotension, hypoxia, nausea, and vomiting, along with gastroenterologist satisfaction and patients' pain score (based on Wong-Baker faces pain assessment scale), were recorded by a checklist." | 5.51 | Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial. ( Aghaali, M; Ahmadpour, S; Alemi, F; Aminnejad, R; Hormati, A; Hormati, M; Sabouri, SM; Saeidi, M; Shafiee, H, 2022) |
"The effectiveness and side effects of dexmedetomidine (DEX) in combination with midazolam and propofol have not been comparatively studied in a single clinical trial as sedative agents to general anesthesia before." | 5.51 | Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery. ( Gao, Y; Yan, F, 2022) |
"BACKGROUND This prospective, randomized, controlled study evaluated the efficacy and safety of remimazolam tosilate sedation with adjuvant sufentanil, relative to propofol, for Chinese patients with liver cirrhosis undergoing gastroscopy." | 5.51 | Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study. ( Cao, Y; Chi, P; Lv, W; Quan, Z; Xue, FS; Zhou, C, 2022) |
" Therefore, the present study sought to evaluate the effect of different doses of esketamine compared with the effect of fentanyl on incidence of perioperative hypotension in patients undergoing painless abortion surgery and to explore the optimal esketamine dose for this population." | 5.51 | Effect of different doses of esketamine compared with fentanyl combined with propofol on hypotension in patients undergoing painless abortion surgery: a prospective, randomized, double-blind controlled clinical trial. ( Chen, J; Hu, B; Shen, M; Wang, F; Yang, Y; Zhou, Q; Zou, X, 2022) |
"In geriatric patients, hypotension is often reported after general anesthesia induction using propofol." | 5.51 | Hypotension after general anesthesia induction using remimazolam in geriatric patients: Protocol for a double-blind randomized controlled trial. ( Goto, T; Masui, K; Mihara, T; Saigusa, Y; Takaki, R; Yamamoto, N; Yokose, M, 2022) |
"Remimazolam was associated with a lower rate of hypotension in elderly patients undergoing upper gastrointestinal endoscopy under deep sedation/anaesthesia than propofol." | 5.51 | Remimazolam versus propofol for deep sedation/anaesthesia in upper gastrointestinal endoscopy in elderly patients: A multicenter, randomized controlled trial. ( Fu, L; Huang, H; Huang, Y; Jiang, J; Liao, Y; Ling, W; Lu, K; Ma, C; Pan, M; Qin, Z; Ran, X; Wang, M; Wei, N; Wei, Q; Wei, S; Wei, Y; Xiong, B, 2022) |
" Both propofol and dexmedetomidine proved to be adequate and safe medications in the sedation of autistic children undergoing MRI." | 5.48 | A Comparison of Safety and Efficacy of Dexmedetomidine and Propofol in Children with Autism and Autism Spectrum Disorders Undergoing Magnetic Resonance Imaging. ( Abulebda, K; Ahmed, SS; Louer, R; Lutfi, R, 2018) |
" Current clinical studies have focused on the use of remimazolam and propofol for general anesthesia (GA) as indicators of safety outcomes in surgical patients, but different studies have reached different conclusions." | 5.41 | Comparison of remimazolam and propofol about safety outcome indicators during general anesthesia in surgical patients: a systematic review and meta-analysis. ( An, L; Bai, X; Chen, R; Gao, H; Huang, X; Tong, R; Wang, C; Wu, X; Yi, J; Zhang, Z, 2023) |
" Propofol is the most widely used agent for induction of anesthesia and sedation by anesthesiologists." | 5.41 | Remimazolam ( Chang, Y; Chi, KY; Huang, YT, 2023) |
"Propofol was commenced in all patients at a mean infusion rate of 18." | 5.38 | Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation. ( Drewitz, I; Heitmann, K; Hoffmann, BA; Rostock, T; Salukhe, TV; Steven, D; Willems, S, 2012) |
"Propofol is an intravenous anesthetic that is widely used to anesthetize patients during neurosurgical procedures." | 5.38 | Opioid receptor blockade prevents propofol-induced hypotension in rats. ( de Moura, RS; Lessa, MA; Maracajá-Neto, LF; Mello Silva, GA; Tibiriçá, E, 2012) |
" We aimed to establish whether the duration of preoperative abstinence from fluids independently contributed to arterial blood pressure changes and dosage requirements during propofol induction." | 5.36 | The influence of duration of fluid abstinence on hypotension during propofol induction. ( Lewis, CM; Morley, AP; Nalla, BP; Natarajan, A; Prevost, AT; Strandvik, G; Vamadevan, S, 2010) |
"Pharmacologic angiotensin axis blockade (AAB) has been associated with profound hypotension following anesthetic induction with propofol." | 5.30 | A randomized controlled trial comparing methohexital and propofol for induction in patients receiving angiotensin axis blockade. ( Adhikary, S; Bonavia, A; Budde, A; Kunselman, A; Lyn-Sue, J; Mets, B; Verbeek, T, 2019) |
"Propofol is commonly used with remifentanil for induction of general anesthesia (GA); however, it often leads to hypotension." | 5.30 | Comparison between hemodynamic effects of propofol and thiopental during general anesthesia induction with remifentanil infusion: a double-blind, age-stratified, randomized study. ( Hino, H; Kihara, Y; Matsuura, T; Mori, T; Nishikawa, K; Tsujikawa, S, 2019) |
"It is unknown to what extent hypotension frequently observed following administration of propofol for induction of general anesthesia is caused by overdosing propofol." | 5.27 | Bispectral index to guide induction of anesthesia: a randomized controlled study. ( Arndt, C; Eberhart, L; Nageldick, D; Rüsch, D; Tappert, S; Wulf, H, 2018) |
"Hypotension is common during propofol sedation for colonoscopy and of a magnitude and duration associated with harm in surgical patients." | 5.22 | Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis. ( Absalom, AR; Barends, CRM; Jones, JB; Sneyd, JR, 2022) |
"Both dexmedetomidine and propofol can effectively reduce anxiety levels of claustrophobic adults undergoing MRI, but dexmedetomidine takes longer to achieve adequate anxiolysis and sleep and may have an effect on image quality." | 5.22 | Comparing the efficacy and safety between propofol and dexmedetomidine for sedation in claustrophobic adults undergoing magnetic resonance imaging (PADAM trial). ( Ariffin, MA; Chan, L; Lai, LL; Loh, PS; Rai, V; Ramli, N, 2016) |
"Phenylephrine 200mcg is more effective than 100mcg in attenuating propofol induced hypotension, especially during the first two minutes after induction, in patients aged 55 years and above." | 5.22 | The effect of prophylactic phenylephrine on systemic hypotension during induction of anaesthesia with propofol in patients over 55 years old. ( Kwok, FY; Venugobal, S, 2016) |
" Hypotension induced by plasma target-controlled infusion of propofol could mainly be attributed to decreased stroke volume instead of vascular dilation." | 5.20 | Hemodynamic responses during induction: comparison of Marsh and Schnider pharmacokinetic models. ( Feng, X; Niu, LJ; Yang, L; Yang, XY; Zhou, X; Zhou, ZB, 2015) |
"The results of this study suggest that nitrous oxide inhalation combined with propofol sedation attenuates the hypotensive effect and pain associated with propofol injections, along with potentiating the amnesic effect." | 5.20 | A prospective, randomized controlled trial of conscious sedation using propofol combined with inhaled nitrous oxide for dental treatment. ( Hanamoto, H; Kudo, C; Morimoto, Y; Niwa, H; Sugimura, M; Yokoe, C, 2015) |
"Propofol is commonly used in pediatric sedation, which may cause hypotension during induction." | 5.20 | A presedation fluid bolus does not decrease the incidence of propofol-induced hypotension in pediatric patients. ( Aldag, JC; Deshpande, GG; Jager, MD, 2015) |
" Hypotension events, induction and recovery time and propofol doses were not different." | 5.17 | The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial. ( Hsieh, CH; Kuo, HP; Lin, HC; Lin, TY; Lo, YL; Ni, YL; Wang, CH; Wang, TY; Yu, CT, 2013) |
"This study shows that high doses of propofol are needed to reach effective sedation in neonates for intubation, with hypotension as a side effect in a considerable percentage of patients." | 5.17 | Clinical evaluation of propofol as sedative for endotracheal intubation in neonates. ( Reiss, IK; Simons, SH; van der Lee, R; van Weissenbruch, MM, 2013) |
"Our study showed that the use of propofol resulted in less hypertension and tachycardia at and after intubation than etomidate." | 5.17 | Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial. ( Kamenik, M; Möller Petrun, A, 2013) |
"Patients scheduled to undergo ESD for early gastric cancer or adenoma were randomly assigned to sedation with midazolam or propofol, and consciousness level was evaluated by bispectral index (BIS) monitoring." | 5.16 | Propofol sedation with bispectral index monitoring is useful for endoscopic submucosal dissection: a randomized prospective phase II clinical trial. ( Azuma, M; Higuchi, K; Ishido, K; Katada, C; Koizumi, W; Naruke, A; Sasaki, T; Sato, A; Tanabe, S, 2012) |
"The utilization of phenylephrine to correct hypotension induced by anesthesia has a negative impact on S(c)O(2) while ephedrine maintains frontal lobe oxygenation potentially related to an increase in CO." | 5.14 | Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia-induced hypotension. ( Brassard, P; Jørgensen, TB; Nissen, P; Secher, NH, 2010) |
"This study was conducted to examine whether pretreatment with intravenous atropine could prevent bradycardia and hypotension during induction of total intravenous anesthesia with propofol and remifentanil in a prospective randomized placebo-controlled manner." | 5.14 | Can intravenous atropine prevent bradycardia and hypotension during induction of total intravenous anesthesia with propofol and remifentanil? ( Ariyama, J; Hayashida, M; Kitamura, A; Maruyama, K; Nakagawa, H; Nishikawa, Y, 2010) |
"The present study compared the efficacy of preloading with colloid "Haemaccel" with vasoconstrictor (intravenous ephedrine sulphate) in preventing hypotension during propofol induction." | 5.13 | Prevention of hypotension during propofol induction: a comparison of preloading with 3.5% polymers of degraded gelatin (Haemaccel) and intravenous ephedrine. ( Bhadani, UK; Bhattarai, BK; Biswas, BK; Dhungana, Y; Tripathi, M, 2008) |
"Propofol produces anaesthesia with rapid recovery but also causes pain or discomfort on injection." | 5.13 | Prevention of propofol-induced injection pain by sufentanil: a placebo-controlled comparison with remifentanil. ( Honarmand, A; Safavi, M, 2008) |
"Propofol is twice as likely as etomidate to evoke hypotension in anaesthesia induction of patients with severe aortic stenosis; however, etomidate transiently decreases post-operative serum cortisol concentrations." | 5.12 | Propofol causes more hypotension than etomidate in patients with severe aortic stenosis: a double-blind, randomized study comparing propofol and etomidate. ( Bendel, S; Pölönen, P; Ruokonen, E; Uusaro, A, 2007) |
"Phenylephrine in doses of 100 micrograms effectively attenuates anticipated hypotension upon induction of general anaesthesia with propofol." | 5.12 | Attenuation of hypotension using phenylephrine during induction of anaesthesia with propofol. ( Imran, M; Khan, FH; Khan, MA, 2007) |
"In 60 patients undergoing inguinal hernia repair, we compared the clinical profile of unilateral spinal anesthesia produced with either 8 mg of hyperbaric bupivacaine 0." | 5.11 | A prospective, randomized, double-blind comparison of unilateral spinal anesthesia with hyperbaric bupivacaine, ropivacaine, or levobupivacaine for inguinal herniorrhaphy. ( Casati, A; Marchetti, C; Moizo, E; Vinciguerra, F, 2004) |
"This prospective, randomized, double-blinded study was designed to compare the effects of desflurane, isoflurane and sevoflurane when combined with remifentanil for induced hypotension on surgical conditions and operative field during tympanoplasty." | 5.11 | Induced hypotension for tympanoplasty: a comparison of desflurane, isoflurane and sevoflurane. ( Aypar, U; Başgül, E; Celiker, V; Dal, D; Ozer, E; Salman, MA, 2004) |
"4%), including hypotension in 5, hypoxemia in 7, and apnea in 5." | 5.11 | Propofol for deep procedural sedation in the ED. ( Baire, M; Frazee, BW; Lowery, D; Park, RS, 2005) |
"This prospective, double-blind, randomized, placebo-controlled study compares the effects of ephedrine and ketamine on injection pain, and hypotension from propofol." | 5.11 | Comparison of ephedrine and ketamine in prevention of injection pain and hypotension due to propofol induction. ( Altunkaya, H; Ayoğlu, H; Ciçek, E; Demirel, CB; Ozer, Y; Ozkoçak, I, 2005) |
"We evaluated the effectiveness of intentional hypercapnia against hypotension after induction of anaesthesia with thiopental and isoflurane (TI) or propofol (P)." | 5.11 | Effect of hypercapnia on arterial hypotension after induction of anaesthesia. ( Enoki, T; Fukuda, K; Nomura, R; Shinomura, T; Tsuchiya, N, 2005) |
"In patients chronically treated with angiotensin converting-enzyme inhibitors (ACEI), typically selected doses of ephedrine do not always restore arterial blood pressure when anesthesia-induced hypotension occurs." | 5.10 | Terlipressin-ephedrine versus ephedrine to treat hypotension at the induction of anesthesia in patients chronically treated with angiotensin converting-enzyme inhibitors: a prospective, randomized, double-blinded, crossover study. ( Bertrand, M; Brun, L; Coriat, P; Gourdin, M; Meersschaert, K; Mouren, S; Riou, B, 2002) |
"Nicardipine-, nitroglycerin-, and prostaglandin E1-induced hypotension attenuate the human cerebrovascular CO2 reactivity during propofol-fentanyl anesthesia." | 5.09 | Effects of nicardipine-, nitroglycerin-, and prostaglandin E1-induced hypotension on human cerebrovascular carbon dioxide reactivity during propofol-fentanyl anesthesia. ( Endoh, H; Honda, T; Komura, N; Shibue, C; Shimoji, K; Watanabe, I, 1999) |
"We conducted a double-blind, randomised, placebo-controlled study evaluating the efficacy of prophylactic metaraminol for preventing propofol-induced hypotension." | 5.09 | The effect of prophylactic metaraminol on systemic hypotension caused by induction of anaesthesia with propofol in patients over 55 years old. ( Chiu, CL; Tew, GP; Wang, CY, 2001) |
" A total of 30 patients were randomly allocated for either normotensive anesthesia maintained by continuous infusion of propofol and remifentanil (NORMO, n=10) or hypotensive anesthesia, whereby hypotension was induced by increasing the infusion rate of remifentanil (HYPO-R, n=10) or by administration of nitroglycerin (HYPO-N, n=10)." | 5.09 | Influence of hypotensive and normotensive anesthesia on platelet aggregability and hemostatic markers in orthognathic surgery. ( Andel, H; Felfernig, M; Felfernig-Boehm, D; Fleck, T; Kimberger, O; Kinstner, C; Mueller, MR; Salat, A, 2001) |
"Pain is a well known complication of propofol injection." | 5.08 | Modulating effects of lignocaine on propofol. ( Khoo, ST; Tham, CS, 1995) |
"The objective of this study was to determine the effectiveness of two prophylactic approaches against the anticipated hypotension induced by propofol during rapid-sequence intubation." | 5.08 | Prophylaxis against the systemic hypotension induced by propofol during rapid-sequence intubation. ( el-Beheiry, H; Kim, J; Milne, B; Seegobin, R, 1995) |
"We compared propofol with high-dose barbiturates in the treatment of refractory status epilepticus (RSE) and propose a protocol for the administration of propofol in RSE in adults, correlating propofol's effect with plasma levels." | 5.08 | Treatment of refractory status epilepticus with propofol: clinical and pharmacokinetic findings. ( Dulaney, E; Kramer, TH; O'Meeghan, R; Raps, EC; Skaar, DJ; Stecker, MM, 1998) |
"To investigate clinically important hypotension and bradycardia after induction of anesthesia with propofol, we analyzed data from a Phase IV stepwise study involving 25,981 patients, 1722 institutions, and 1819 anesthesiologists." | 5.07 | Hemodynamic effects of propofol: data from over 25,000 patients. ( Apfelbaum, JL; Grasela, TH; Hug, CC; McLeskey, CH; Nahrwold, ML; Roizen, MF; Stanley, TH; Thisted, RA; Walawander, CA; White, PF, 1993) |
"The present investigation explored the possibility that the commonly observed hypotension that occurs during induction of anesthesia with propofol might be related to its ability to produce venodilation." | 5.07 | Venodilation contributes to propofol-mediated hypotension in humans. ( Berens, RA; Ebert, TJ; Kampine, JP; Muzi, M, 1992) |
"This study investigated whether pretreatment with glycopyrronium can attenuate the hypotension caused by anaesthesia of the elderly with propofol." | 5.07 | The effect of pre-induction glycopyrronium on the haemodynamic response of elderly patients to anaesthesia with propofol. ( Mayall, R; Sneyd, JR, 1992) |
" The effects of propofol on cecal intubation rates, and occurrences of hypotension and apnea were similar to those of TAs." | 5.05 | Safety and efficacy of propofol alone or in combination with other agents for sedation of patients undergoing colonoscopy: an updated meta-analysis. ( Li, HT; Xu, H; Zhang, K, 2020) |
" Providers of all sedation types should be aware of hypotension, apnea, hypoventilation, and hypoxia that can develop and they should be able to manage the patient under these circumstances." | 5.01 | Moderate and deep sedation training and pharmacology for nonanesthesiologists: recommendations for effective practice. ( Beutler, SS; Tran, TT; Urman, RD, 2019) |
"We are uncertain whether maintenance with propofol-based TIVA or with inhalational agents affect incidences of postoperative delirium, mortality, or length of hospital stay because certainty of the evidence was very low." | 4.98 | Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. ( Alderson, P; Lewis, SR; Miller, D; Pritchard, MW; Schofield-Robinson, OJ; Shelton, CL; Smith, AF, 2018) |
"17), and the reduction in apnea or hyoxemia (OR=0." | 4.95 | The Comparison of Etomidate and Propofol Anesthesia in Patients Undergoing Gastrointestinal Endoscopy: A Systematic Review and Meta-Analysis. ( Xiao, X; Ye, L; Zhu, L, 2017) |
", hypoxia, hypotension, arrhythmia, and apnea) and sedation profiles were assessed." | 4.89 | The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis. ( Chen, C; Chen, J; Deng, D; Liu, J; Long, A; Tang, D; Wang, D; Wang, L; Xu, Y; Zhu, Z, 2013) |
" The following 4 cardiopulmonary complications were assessed: hypoxia, hypotension, arrhythmias, and apnea." | 4.82 | Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. ( Khandwala, F; Lopez, R; Qadeer, MA; Vargo, JJ; Zuccaro, G, 2005) |
"These findings suggest that 5-ALA-HCl does not affect the antihypertensive agents-induced hypotensive effect, but enhances the bupivacaine-induced hypotensive effect, especially in SHRs, indicating that 5-ALA may contribute to anesthesia-induced hypotension via suppression of sympathetic nerve activity in patients with hypertension." | 4.31 | 5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. ( Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N, 2023) |
"In this study, the aim was to research the effects of smoking habits on controlled hypotension administered with nitroglycerin during ear-nose-throat surgery." | 4.31 | Effects of smoking on controlled hypotension with nitroglycerin during ear-nose-throat surgery. ( Ersoy, A; Sinoglu, B, 2023) |
" Within 48 h of admission, we compared total amounts of sedation/pain medications (morphine milligram equivalents (MME), propofol, dexmedetomidine, benzodiazepines) with total resuscitation volumes and frequency of hypotensive episodes." | 4.31 | The risks of sedation and pain control during burn resuscitation: Increased opioids lead to over-resuscitation and hypotension. ( Anderson, J; Mandell, SP; McClellan, JM; O'Neal, J; Sheckter, C; Stanton, E, 2023) |
"The objective of this study was to compare the development of clinically significant hypotension or bradycardia (ie, negative hemodynamic event) between critically ill adults receiving sedation with ketamine and either propofol or dexmedetomidine." | 4.12 | Hemodynamic Effects of Ketamine Compared With Propofol or Dexmedetomidine as Continuous ICU Sedation. ( Atchley, E; Bauer, A; Benken, S; Meyer, R; Pulver, M; Tesoro, E, 2022) |
"Anaesthesia with propofol is frequently associated with hypotension, which is at least partially attributable to increased nitric oxide (NO) formation derived from the activation of protein kinase C (PKC)/endothelial NO synthase (NOS3) axis." | 4.12 | Gene-gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol. ( Ferreira, GC; Garcia, LV; Lacchini, R; Luizon, MR; Oliveira-Paula, GH; Paula-Garcia, WN; Pereira, DA; Pinheiro, LC; Tanus-Santos, JE, 2022) |
"The primary exposure was total propofol induction dose in mg/kg, and the primary outcome was occurrence of severe hypotension (MAP≤55 mmHg) prior to surgical incision, stratified by non-invasive vs." | 4.12 | Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65. ( Akhtar, S; Bardia, A; Burg, MM; Dai, F; Kheterpal, S; Mathis, M; Michel, G; Schonberger, RB; Shah, N; Vaughn, MT, 2022) |
"Although the largest decrease in propofol dosage required for intubation was after IV premedication with acepromazine and butorphanol, hypotension and apnea still occurred." | 4.12 | Effects of intravenous acepromazine and butorphanol on propofol dosage for induction of anesthesia in healthy Beagle dogs. ( Dantino, SC; Kleine, SA; Seddighi, R; Smith, CK; Smith, SM; Zhu, X, 2022) |
"Hypotension that is resistant to phenylephrine is a complication that occurs in anesthetized patients treated with angiotensin converting enzyme (ACE) inhibitors." | 4.12 | Blockade of endothelial Mas receptor restores the vasomotor response to phenylephrine in human resistance arterioles pretreated with captopril and exposed to propofol. ( Freed, JK; Hockenberry, JC; Katunaric, B; Pagel, PS; Schulz, ME, 2022) |
"The development of hypotension on administration of intravenous propofol is common and independently associated with adverse outcomes." | 4.02 | Predicting hypotension during anesthesia: Variation in pulse oximetry plethysmography predicts propofol-induced hypotension in children. ( Choi, SN; Jang, YE; Ji, SH; Kim, EH; Kim, HS; Kim, JT; Lee, JH, 2021) |
" This report describes a case of severe bradyarrhythmia during anesthetic induction with propofol, midazolam, sufentanil, and vecuronium." | 4.02 | Bradyarrhythmia and hypotension during anesthetic induction-reconsideration of nifedipine: a case report. ( Zhang, X, 2021) |
" We hypothesised that anaesthesia-induced hypotension causes renal vasoconstriction and decreased oxygen delivery via angiotensin II-mediated renal vasoconstriction." | 3.96 | Pre-treatment with the angiotensin receptor 1 blocker losartan protects renal blood flow and oxygen delivery after propofol-induced hypotension in pigs. ( Franzén, S; Frithiof, R, 2020) |
"To compare the development of clinically significant hemodynamic event (ie, hypotension or bradycardia) in adults with septic shock receiving either propofol or dexmedetomidine." | 3.96 | Effects From Continuous Infusions of Dexmedetomidine and Propofol on Hemodynamic Stability in Critically Ill Adult Patients With Septic Shock. ( Hammond, DA; Nelson, KM; Patel, GP, 2020) |
"Propofol anesthesia is usually accompanied by hypotension." | 3.88 | Angiotensin converting enzyme inhibitors enhance the hypotensive effects of propofol by increasing nitric oxide production. ( Ferreira, GC; Garcia, LV; Garcia, WNP; Lacchini, R; Oliveira-Paula, GH; Pinheiro, LC; Tanus-Santos, JE, 2018) |
"In early 2015, clinicians throughout Zambia noted a range of unpredictable adverse events after the administration of propofol, including urticaria, bronchospasm, profound hypotension, and most predictably an inadequate depth of anesthesia." | 3.85 | An Analysis of Substandard Propofol Detected in Use in Zambian Anesthesia. ( Attaran, A; Bould, MD; Curtis, S; Mayer, P; Mumphansha, H; Nickerson, JW; Overton, S, 2017) |
"Hypotension is a common side effect of propofol, but there are no reliable methods to determine which patients are at risk for significant propofol-induced hypotension (PIH)." | 3.83 | Ultrasound measurement of inferior vena cava collapse predicts propofol-induced hypotension. ( Au, AK; Fields, JM; Ku, BS; Papanagnou, D; Shirazi, M; Steinberg, D; Thom, C, 2016) |
"A multicenter, retrospective, propensity-matched pilot study was conducted comparing patients with sepsis or severe sepsis who received CIV propofol for sedation to those who did not." | 3.83 | Effects of propofol on vasopressor use in patients with sepsis and severe sepsis: A pilot study. ( Boucher, AN; Jones, GM; Kimmons, LA; Marler, J; Mohrien, K; Oliphant, CS; Vandigo, JE, 2016) |
" The effects of isoflurane, propofol, apnea, and hypotension on lower extremity MEPs were studied." | 3.81 | Methodology of motor evoked potentials in a rabbit model. ( Bombien, R; Goodwin, E; Haji, F; Juan, V; Khoynezhad, A; Lapchak, PA; Rastegar, M; Waterford, SD, 2015) |
"Hypotension was the most frequent anesthetic complication during procedure under propofol-based deep sedation, but this method was safe and effective under appropriate monitoring." | 3.81 | Age correlates with hypotension during propofol-based anesthesia for endoscopic retrograde cholangiopancreatography. ( Khoi, CS; Lin, TY; Lu, CW; Wang, HC; Wong, JJ, 2015) |
" Univariate analyses were performed to determine risk factors associated with severe hypotension during sedation with propofol." | 3.80 | Predictors of severe hypotension in neurocritical care patients sedated with propofol. ( Doepker, BA; Elijovich, L; Erdman, MJ; Jones, GM; Kimmons, LA, 2014) |
"Severe hypotension and bradycardia occur at similar prevalence in neurocritical care patients who receive dexmedetomidine or propofol." | 3.80 | A comparison of severe hemodynamic disturbances between dexmedetomidine and propofol for sedation in neurocritical care patients. ( Doepker, BA; Elijovich, L; Erdman, MJ; Gerlach, AT; Jones, GM; Phillips, GS, 2014) |
" We report a case of profound hypotension after anesthesia induction with propofol in a patient who was treated with two 600 mg doses of rifampin for prophylaxis of infection before surgery." | 3.79 | Case report: profound hypotension after anesthetic induction with propofol in patients treated with rifampin. ( Ehrenfeld, JM; Jiang, Y; Mirzakhani, H; Nozari, A; Peterfreund, R; Rosow, C; Sandberg, W; Szabo, M; Walsh, JL; Wang, J, 2013) |
"The mortality rates in the present study were extremely high; further hypotension and elevations in plasma pro-inflammatory and anti-inflammatory cytokine concentrations after endotoxin injection were not attenuated by mild hyperthermia between 39 °C and 40 °C, but they were attenuated by propofol with mild hyperthermia." | 3.78 | Effects of propofol with hyperthermia in a rat model of endotoxemic shock. ( Mukawa, C; Taniguchi, T, 2012) |
"Propofol is commonly used to induce anesthesia but has been associated with some negative cardiovascular side effects, including negative inotropy, hypotension, and bradycardia." | 3.77 | The intravenous anesthetic propofol inhibits human L-type calcium channels by enhancing voltage-dependent inactivation. ( Elmslie, KS; Fassl, J; High, KM; Stephenson, ER; Yarotskyy, V, 2011) |
"Higher doses of dexmedetomidine may result in higher incidence of hypotension, longer LOS, and increased concomitant analgesic, sedative, and antipsychotic use, requiring further evaluation in trauma patients." | 3.77 | Evaluation of dexmedetomidine: safety and clinical outcomes in critically ill trauma patients. ( Devabhakthuni, S; Kufera, JA; Pajoumand, M; Stein, DM; Watson, K; Williams, C, 2011) |
"Although obesity was associated with an increased frequency of SRCs, propofol sedation can be used safely in obese patients undergoing AEPs when administered by trained professionals." | 3.77 | Obesity as a risk factor for sedation-related complications during propofol-mediated sedation for advanced endoscopic procedures. ( Azar, R; Cote, GA; Early, D; Edmundowicz, SA; Hall, M; Hovis, CE; Hovis, RM; Jonnalagadda, SS; Kushnir, V; Mullady, DK; Murad, F; Waldbaum, L; Wani, S, 2011) |
" Propofol generally offered good intubating conditions, but we encountered severe problems with arterial hypotension." | 3.76 | Propofol as an induction agent for endotracheal intubation can cause significant arterial hypotension in preterm neonates. ( Eifinger, F; Huenseler, C; Kribs, A; Oberthuer, A; Roth, B; Welzing, L, 2010) |
" Independent predictors of PIH were high BMI, high American Society of Anesthesiology status, propofol coinduction, baseline hypotension, age and preincision duration." | 3.76 | High BMI in children as a risk factor for intraoperative hypotension. ( Blum, J; Cowan, A; Kheterpal, S; Maclean, S; Nafiu, OO; Tremper, KK, 2010) |
"The authors report a case of short-term high-dose propofol-related metabolic acidosis in a 3-year-old girl." | 3.74 | Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report. ( Muhonen, MG; Nwagwu, CI; Westhout, FD, 2007) |
"In two patients, pheochromocytoma resection was performed under propofol/fentanyl anesthesia, while bispectral index (BIS) monitoring and blood volume measurement using pulse spectrophotometry were done." | 3.73 | [Anesthetic management with propofol for pheochromocytoma resection under monitoring of bispectral index and blood volume]. ( Ishida, K; Matsumoto, M; Morimoto, Y; Orita, H; Sakabe, T; Tsuruta, S; Utada, K, 2006) |
" The adverse event (AE) rate was 18% and included apnea (10%), inadequate sedation (3%), bradycardia (2%), desaturation (1%), hypotension (1%) and bag-valve-mask use (1%)." | 3.73 | Emergency department procedural sedation and analgesia: A Canadian Community Effectiveness and Safety Study (ACCESS). ( Mensour, M; Michaud, J; Pineau, R; Sahai, V, 2006) |
" There had not been severe hypotension reported in the literature in consequence of inadvertent epidural thiopental administration." | 3.73 | Intravenous propofol precipitates the hypotension induced by inadvertent epidural thiopental injection. ( Chan, KH; Chang, WK; Chu, CC; Huang, SY; Wang, CC, 2006) |
"During incomplete cerebral ischemia, the neuroprotective anesthetics sevoflurane and propofol suppressed cerebral increases in norepinephrine and glutamate concentrations." | 3.72 | The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats. ( Blobner, M; Engelhard, K; Hoffman, WE; Kochs, E; Matthes, B; Werner, C, 2003) |
"Propofol may cause hypotension and the mechanism is complex." | 3.69 | Propofol inhibits medullary pressor mechanisms in cats. ( Chai, CY; Chen, SY; Luk, HN; Wu, WC; Yang, CY, 1997) |
" The objective of this study was to compare the safety and efficacy profiles of the remimazolam and propofol when combined with alfentanil for sedation during ERCP procedures." | 3.30 | A randomized, controlled clinical trial comparing remimazolam to propofol when combined with alfentanil for sedation during ERCP procedures. ( Chen, HR; Dong, SA; Guo, Y; Li, HX; Li, WZ; Liu, SS; Song, K; Wang, JH; Wu, LL; Wu, LN; Yu, JB; Zhang, L, 2023) |
"Esketamine is an S (+) enantiomer of ketamine with greater potency and similar psychomimetic effects compared to racemic ketamine." | 3.30 | Safety and tolerability of esketamine in propofol based sedation for endoscopic variceal ligation with or without injection sclerotherapy: Randomized controlled trial. ( Chen, J; Chen, X; Chen, Y; Dan, L; Duan, G; Huang, H; Liu, R; Lyu, H; Wang, Q; Wang, T, 2023) |
" The primary outcome was the incidence of intraoperative cardiopulmonary adverse events (a composite outcome of hypotension, bradycardia and hypoxemia)." | 3.30 | Cardiopulmonary Adverse Events of Remimazolam versus Propofol During Cervical Conization: A Randomized Controlled Trial. ( Huang, Z; Ma, L; Mu, X; Nie, H; Wang, L; Wang, Y; Zheng, Z, 2023) |
"Remimazolam tosilate (RT) is a novel short-acting GABA (A) receptor agonist that has a rapid recovery from procedural sedation and can be fully reversed by flumazenil." | 3.30 | Efficacy and safety of remimazolam tosilate versus propofol in patients undergoing day surgery: a prospective randomized controlled trial. ( Huang, J; Liu, M; Luo, W; Miao, C; Sun, M; Wan, J; Xia, L; Xiong, W; Xu, P; Zhang, J; Zhang, X; Zhang, Z; Zhong, J, 2023) |
" The aim of this study was to investigate the effects of remimazolam besylate combined with alfentanil in patients undergoing fiberoptic bronchoscopy with preserved spontaneous breathing." | 3.30 | Effectiveness of remimazolam besylate combined with alfentanil for fiberoptic bronchoscopy with preserved spontaneous breathing: a prospective, randomized, controlled clinical trial. ( Chen, ZJ; Li, JY; Wang, JF; Xu, L; Yu, L; Zhang, L, 2023) |
"Reducing hypotension is crucial as hypotension is the most common side effect of spinal anesthesia, and in older patients with various comorbidities, it can lead to fatality." | 3.30 | Norepinephrine prevents hypotension in older patients under spinal anesthesia with intravenous propofol sedation: a randomized controlled trial. ( Cho, J; Kim, H; Kim, HJ; Kim, KS; Koh, WU; Lee, S; Park, SW; Ro, YJ, 2023) |
" The occurrence and types of treatment-emergent adverse events were similar among the 3 arms, both with a severity of grade 1 or 2." | 3.11 | Efficacy and safety of HSK3486 for the induction and maintenance of general anesthesia in elective surgical patients: a multicenter, randomized, open-label, propofol-controlled phase 2 clinical trial. ( Deng, J; Guan, YJ; Guo, QL; Lin, ZM; Liu, J; Liu, YF; Ma, EL; Wang, DX; Wei, XC; Yang, MC; Yu, XD; Zeng, Y; Zheng, H, 2022) |
"Remimazolam is an ultrashort-acting benzodiazepine that is potentially a practical option for procedural sedation in colonoscopy." | 3.11 | Discharge readiness after remimazolam versus propofol for colonoscopy: A randomised, double-blind trial. ( Chen, L; Fu, B; Guan, J; Liu, L; Yao, Y; Zheng, X, 2022) |
"However, adverse events such as hypoxemia often occur clinically." | 3.11 | Effects of intravenous lidocaine on hypoxemia induced by propofol-based sedation for gastrointestinal endoscopy procedures: study protocol for a prospective, randomized, controlled trial. ( An, LX; Qi, XR; Sun, JY; Xue, FS; Zhang, K, 2022) |
"Remimazolam is a novel ultra-short-acting benzodiazepine." | 3.11 | Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy. ( Chang, H; Liao, Q; Qing, W; Tong, J; Yu, R; Zhang, F, 2022) |
"Remimazolam is a new type of benzodiazepine drug, with supposed advantages of rapid induction, rapid recovery, stable hemodynamics, and mild respiratory inhibition." | 3.01 | Effect of remimazolam induction on hemodynamics in patients undergoing valve replacement surgery: A randomized, double-blind, controlled trial. ( Chen, J; Chen, Y; He, F; Lai, T; Liu, T; Lu, Y; Xie, Y, 2021) |
"Periintubation hypotension is associated with poor outcomes in the critically ill." | 2.90 | Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial. ( Bauer, PR; Brown, DR; Gajic, O; Gallo De Moraes, A; Hoskote, SS; Iyer, VN; Nicholson, WT; Oeckler, RA; Pickering, B; Schroeder, DR; Smischney, NJ, 2019) |
"Postoperative respiratory depression was defined as rate <10/min, hypercapnia/hypercarbia-arterial CO2 tension >50 mmHg or SO2 <90 while hypotension was defined as a decrease of 20 % in mean blood pressure compared to initial values." | 2.82 | Propofol-ketamine combination: a choice with less complications and better hemodynamic stability compared to propofol? On a prospective study in a group of colonoscopy patients. ( Babayıgıt, M; Baykal Tutal, Z; Derelı, N; Gulec, H; Horasanlı, E; Inceoz, H; Kurtay, A, 2016) |
" Propofol-based sedation is simple, easy to use, and effective, but is not without cardiovascular and respiratory adverse effects." | 2.82 | A randomized, controlled trial to compare the efficacy and safety profile of a dexmedetomidine-ketamine combination with a propofol-fentanyl combination for ERCP. ( Goyal, R; Hasnain, S; Mittal, S; Shreevastava, S, 2016) |
"Hypotension was defined as systolic blood pressure (SBP) < 90 mmHg, MAP < 60 mmHg, or a reduction in either SBP or MAP > 20% from baseline values." | 2.82 | Prewarming neurosurgical patients to minimize hypotension on induction of anesthesia: a randomized trial. ( Darvall, J; Leslie, K; Vijayakumar, R, 2016) |
"16." | 2.82 | Etomidate plus propofol versus propofol alone for sedation during gastroscopy: a randomized prospective clinical trial. ( Chen, LM; Chen, M; Gan, GS; Ji, M; Li, BX; Song, XY; Tao, J; Wu, MC; Zhang, S; Zhang, YH; Zhou, X, 2016) |
"The primary outcome assessed was hypoxemia incidence." | 2.82 | Determination of the appropriate propofol infusion rate for outpatient upper gastrointestinal endoscopy-a randomized prospective study. ( Li, Q; Xiao, W; Zhou, H; Zhou, Q, 2016) |
" Monitoring by means of the bispectral index (BIS) has shown its utility in reducing the use of drugs and their adverse events in general anesthesia, but evidence in prolonged sedation is insufficient." | 2.82 | Bispectral Index Monitoring Reduces the Dosage of Propofol and Adverse Events in Sedation for Endobronchial Ultrasound. ( Bello, S; Chacón, E; De Pablo, F; Júdez, D; Martínez Ubieto, J; Mincholé, E; Pascual, A; Quesada, N, 2016) |
"Determine the best propofol pharmacokinetic model that meets patient requirements and is devoid of major haemodynamic side effects." | 2.80 | Comparison of the hemodynamic response to induction and intubation during a target-controlled infusion of propofol with 2 different pharmacokinetic models. A prospective ramdomized trial. ( Alonso Rodriguez, E; Asensio Merino, F; Castilla, MS; Ramos Luengo, A, 2015) |
"To assess the effects of dexmedetomidine (Dex) on propofol dosage in target-controlled infusion (TCI) and hemodynamics in patients undergoing laparoscopic surgery under general anesthesia." | 2.80 | [Effects of dexmedetomidine on propofol dosage in target-controlled infusion and hemodynamics during laparoscopic surgery under general anesthesia]. ( Liang, FG; Ouyang, MW; Wang, HT, 2015) |
"Propofol was administered by a target-controlled infusion system to attain and maintain a plasma propofol concentration of 1." | 2.79 | The effect of nitrous oxide inhalation on the hypotensive response to propofol: a randomized controlled trial. ( Boku, A; Hanamoto, H; Kudo, C; Morimoto, Y; Niwa, H; Sugimura, M; Yokoe, C, 2014) |
"Propofol does not increase complications even in a collective with pre-existing impairment of LVEF." | 2.79 | Minimal and deep sedation during ablation of ventricular tachycardia. ( Attanasio, P; Blaschke, F; Boldt, LH; Haverkamp, W; Huemer, M; Loehr, L; Mueller, A; Parwani, AS; Storm, C; Wutzler, A, 2014) |
"Propofol was infused at a dose determined by a modified Dixon's up-and-down method." | 2.79 | Intrathecal fentanyl decreases the optimal effect site concentration of propofol during spinal anaesthesia. ( Kim, JS; Kim, JY; Kim, MK; Kim, SH; Lee, JS, 2014) |
" Additionally, propofol dosage and overall rate of adverse events in group Cs were lower than those in group Cc." | 2.78 | Stepwise sedation for elderly patients with mild/moderate COPD during upper gastrointestinal endoscopy. ( Cao, K; Chen, X; Guo, Q; Jia, Y; Liu, XM; Shen, SR; Tong, LL; Wang, F; Wang, XY; Xiao, DH; Xu, CX; Zou, HF, 2013) |
"Propofol is a widely used anesthetic drug because of its minor complication and also its fast effect." | 2.77 | Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial. ( Ayatollahi, V; Behdad, S; Kargar, S; Yavari, T, 2012) |
"Hypotension was treated with fluids and vasopressors using a standardised algorithm." | 2.76 | Effect of auditory evoked potential-guided anaesthesia on consumption of anaesthetics and early postoperative cognitive dysfunction: a randomised controlled trial. ( Berggren, L; Gupta, A; Hallén, JL; Jildenstål, PK; Rawal, N, 2011) |
"Patients with liver cirrhosis frequently undergo diagnostic or therapeutic upper GI endoscopy (UGIE), and the liver disease might impair the metabolism of drugs usually administered for sedation." | 2.76 | Sedation during upper GI endoscopy in cirrhotic outpatients: a randomized, controlled trial comparing propofol and fentanyl with midazolam and fentanyl. ( Bonilha, DQ; Brito, JR; Correia, LM; Ferrari, AP; Gomes, GF; Lenz, L; Libera, ED; Nakao, FS; Rohr, MR, 2011) |
"Propofol is a sedative-hypnotic with a rapid onset of action." | 2.76 | Feasibility and safety of propofol sedation in flexible bronchoscopy. ( Grendelmeier, P; Kurer, G; Pflimlin, E; Stolz, D; Tamm, M, 2011) |
"The remifentanil consumption was much lower in group RP-E." | 2.74 | Hypotensive anesthesia with esmolol. Assessment of hemodynamics, consumption of anesthetic drugs, and recovery. ( Gökçe, BM; Karabiyik, L; Karadenizli, Y, 2009) |
"Propofol was administered in a bolus of 1 mg/kg, followed by additional doses of 0." | 2.71 | Propofol for procedural sedation in children in the emergency department. ( Anderson, JL; Bassett, KE; Guenther, E; Pribble, CG, 2003) |
"Patients receiving propofol reached full recovery sooner (16." | 2.71 | Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists. ( Chadalawada, V; Hansen, JJ; Liangpunsakul, S; Mendel, AM; Overley, CA; Rex, DK; Strahl, E; Symms, MR; Ulmer, BJ, 2003) |
"Hypotension was documented in two patients in the propofol group and one patient receiving midazolam/meperidine." | 2.71 | Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study. ( Riphaus, A; Stergiou, N; Wehrmann, T, 2005) |
"Ephedrine 0." | 2.69 | Prophylactic ephedrine attenuates the hemodynamic response to propofol in elderly female patients. ( Bentzon, MW; Helbo-Hansen, HS; Køhler, F; Lorenzen, AG; Michelsen, I; Rydlund, E, 1998) |
"Glycopyrrolate was given to significantly more patients in group III (P < 0." | 2.68 | A comparison of propofol and isoflurane anaesthesia: the need for ephedrine and glycopyrrolate. ( Eintrei, C; Granfeldt, H; Jensen, AG; Kalman, SH; Nyström, PO, 1995) |
" The results of this trial suggest that a propofol-based anesthetic, when compared to an enflurane-based anesthetic requiring additional dosing of fentanyl and midazolam for CPB, can lead to a significant reduction in time to extubation after CABG surgery, without adverse hemodynamic effects, increased risk of myocardial ischemia or infarction." | 2.68 | Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery. ( Buckland, MR; Bujor, MA; Davis, BB; Hunt, JO; Langley, M; McRae, R; Moloney, JT; Myles, PS; Weeks, AM, 1997) |
"Propofol sedation has a similar risk of cardiopulmonary adverse events compared with traditional agents for gastrointestinal endoscopic procedures." | 2.55 | Similar Risk of Cardiopulmonary Adverse Events Between Propofol and Traditional Anesthesia for Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis. ( Garg, S; Issa, D; Lopez, R; Sanaka, MR; Vargo, JJ; Wadhwa, V, 2017) |
" Half concluded that propofol was sufficiently safe; three reviews noted a higher occurrence of adverse events, particularly respiratory depression (upper estimate 1." | 2.53 | What Works and What's Safe in Pediatric Emergency Procedural Sedation: An Overview of Reviews. ( Evered, L; Foisy, M; Hartling, L; Klassen, TP; Lang, ES; Milne, A; Sinclair, D, 2016) |
"Propofol is a sedative-hypnotic that exerts its actions through agonism of GABAA receptors at a different binding site than benzodiazepines and reduces glutamatergic activity through N-methyl-d-aspartase (NMDA) receptor blockade." | 2.53 | Propofol for Treatment of Refractory Alcohol Withdrawal Syndrome: A Review of the Literature. ( Brotherton, AL; Hamilton, EP; Hammond, DA; Kloss, HG, 2016) |
"Midazolam was associated with the deterioration of psychometric scores for a longer period than propofol." | 2.52 | Propofol versus midazolam for upper gastrointestinal endoscopy in cirrhotic patients: a meta-analysis of randomized controlled trials. ( Chen, CY; Chen, TL; Ko, CL; Lin, YC; Lou, HY; Tam, KW; Tsai, HC, 2015) |
"Propofol is a potent intravenous anesthetic agent that rapidly induces sedation and unconsciousness." | 2.47 | Clinical effects and lethal and forensic aspects of propofol. ( Levy, RJ, 2011) |
"Descriptive features of sedation including adverse events." | 2.42 | The safe and effective use of propofol sedation in children undergoing diagnostic and therapeutic procedures: experience in a pediatric ICU and a review of the literature. ( Ponaman, ML; Poss, BW; Vaux, KK; Wheeler, DS, 2003) |
"Propofol is a short-acting intravenous anesthetic commonly utilised in the intensive care unit (ICU) for sedation of mechanically ventilated patients." | 2.40 | Propofol for sedation in the intensive care unit: essentials for the clinician. ( Marinella, MA, 1997) |
"A 67-year-old woman with hypertension, type 2 diabetes mellitus, and hypothyroidism presented for an elective blepharoplasty." | 1.91 | A 67-Year-Old Woman With Fluctuating Hypertension and Hypotension After Elective Surgery. ( Ho, C; Lau, C, 2023) |
" We examined here whether ARG1 and ARG2 genotypes and haplotypes affect the changes in blood pressure and NO bioavailability in response to propofol." | 1.62 | Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability. ( Coeli-Lacchini, FB; Ferezin, LP; Ferreira, GC; Garcia, LV; Lacchini, R; Oliveira-Paula, GH; Paula-Garcia, WN; Pinheiro, LC; Tanus-Santos, JE, 2021) |
"Propofol is an intravenous anesthetic agent commonly used intraoperatively as well as in the intensive care unit." | 1.62 | Propofol-induced uric acid crystals: A case of cloudy urine. ( Baumgarten, A; Newton, M, 2021) |
"Bradycardia was experienced by 11." | 1.56 | Use of Propofol Plus Dexmedetomidine in Patients Experiencing Severe Alcohol Withdrawal in the Intensive Care Unit. ( Love, K; Zimmermann, AE, 2020) |
"Propofol was commonly used and is potentially associated with poorer clinical outcomes." | 1.56 | Comparison of drugs used for intubation of pediatric trauma patients. ( Davidson, J; Merritt, N; Mudri, M; Priestap, F; Williams, A, 2020) |
"Hypotension was observed in 23 patients (4." | 1.56 | Propofol sedation with a target-controlled infusion pump in elderly patients undergoing ERCP. ( Akimoto, Y; Kato, H; Ogawa, T; Okada, H; Tanaka, S; Tomoda, T, 2020) |
" Adverse effect profiles and clinical outcome, in the cohorts are largely similar." | 1.56 | DEXmedetomidine compared to PROpofol in NEurocritical Care [DEXPRONE]: A multicenter retrospective evaluation of clinical utility and safety. ( Armahizer, MJ; Heavner, MS; Kurczewski, L; Maciel, CB; Owusu, KA; Zichichi, A, 2020) |
"Propofol-based sedation without endotracheal intubation is safe for ESD procedures in the esophagus and stomach with low anesthesia-related complication rates and short hospital stay." | 1.51 | Propofol sedation without endotracheal intubation is safe for endoscopic submucosal dissection in the esophagus and stomach. ( Bruno, MJ; Hilkemeijer, T; Klimek, M; Koch, AD; Leliveld, L; van de Ven, S, 2019) |
" Adverse events in CAPS patients were recorded." | 1.51 | Computer-Assisted Propofol Sedation for Esophagogastroduodenoscopy Is Effective, Efficient, and Safe. ( Beecher, R; Chiorean, M; Drennan, F; Gluck, M; Koch, J; Kozarek, RA; La Selva, D; Larsen, M; Lin, OS; McCormick, S; Ross, A; Tombs, D; Venu, N; Weigel, W, 2019) |
" Both propofol and dexmedetomidine proved to be adequate and safe medications in the sedation of autistic children undergoing MRI." | 1.48 | A Comparison of Safety and Efficacy of Dexmedetomidine and Propofol in Children with Autism and Autism Spectrum Disorders Undergoing Magnetic Resonance Imaging. ( Abulebda, K; Ahmed, SS; Louer, R; Lutfi, R, 2018) |
"Single-center, retrospective review of trauma patients intubated in the emergency department." | 1.48 | Hemodynamic Effects of Propofol for Induction of Rapid Sequence Intubation in Traumatically Injured Patients. ( Delgado, SD; Dietrich, SK; Dunn, JA; Floren, M; Knapp, VE; Mixon, MA; Rogoszewski, RJ, 2018) |
" Secondary end points included procedural success rates, polyp detection rates, adverse events, and procedure/recovery times." | 1.46 | The First US Clinical Experience With Computer-Assisted Propofol Sedation: A Retrospective Observational Comparative Study on Efficacy, Safety, Efficiency, and Endoscopist and Patient Satisfaction. ( Beecher, R; Gluck, M; Jensen, A; Kozarek, RA; La Selva, D; Lin, OS; Ross, A; Tombs, D; Weigel, W, 2017) |
"Propofol Ce was simulated by inputting the propofol administration profiles of patients into a pediatric compartmental model (Choi model)." | 1.46 | A Simulation Study of Propofol Effect-Site Concentration for Appropriate Sedation in Pediatric Patients Undergoing Brain MRI: Pharmacodynamic Analysis. ( Byon, HJ; Han, DW; Jung, HH; Kim, SY; Na, SH; Song, Y, 2017) |
"Hypotension was significantly more common among patients with COPD." | 1.46 | Flexible bronchoscopy with moderate sedation in COPD: a case-control study. ( Grendelmeier, P; Jahn, K; Pflimlin, E; Stolz, D; Tamm, M, 2017) |
"Attention to hypoxemia is necessary in elderly patients, particularly patients with abnormal pulmonary function." | 1.43 | Propofol sedation with a target-controlled infusion pump and bispectral index monitoring system in elderly patients during a complex upper endoscopy procedure. ( Abe, M; Gotoda, T; Hori, K; Iwamuro, M; Kanzaki, H; Kawahara, Y; Kawano, S; Kita, M; Kono, Y; Miura, K; Okada, H; Yamamoto, K, 2016) |
"Mild hypoxemia occurred in 24% of cases and resolved with nasal cannula." | 1.43 | Deep Sedation for Pediatric Dental Procedures: Is this a Safe and Effective Option? ( Ahmed, SS; Hicks, SR; Nitu, ME; Slaven, JE, 2016) |
"Propofol cessation was necessary in 24 of 205 procedures." | 1.43 | Propofol sedation administered by cardiologists for patients undergoing catheter ablation for ventricular tachycardia. ( Höfeler, T; Hoffmann, BA; Lüker, J; Schäffer, B; Servatius, H; Steven, D; Sultan, A; Willems, S, 2016) |
" We compared adverse event rates in MCI and TCI groups and assessed independent risk factors for adverse events." | 1.43 | Safety of Target-Controlled Propofol Infusion by Gastroenterologists in Patients Undergoing Endoscopic Resection. ( Jang, MK; Kang, SS; Kim, HS; Kim, HY; Lee, JS; Ryu, JY; Seo, SI; Shin, WG, 2016) |
"For propofol, there was a significantly lower dosing for older patients: 17% for patients aged 65-79 and 29% for those aged >80, which was still in less than the recommendations." | 1.43 | Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice. ( Akhtar, S; Burg, MM; Dai, F; Heng, J; Liu, J; Schonberger, RB, 2016) |
"Weight-adjusted anesthetic induction dosing, age-associated differences in dosing by ASA-PS (American Society of Anesthesiology-Physical Status), and hemodynamic outcomes between younger (18-64 years, n = 537) and older (≥65 years, n = 231) female patients were analyzed." | 1.43 | A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients? ( Akhtar, S; Burg, MM; Dai, F; Heng, J; Schonberger, RB, 2016) |
"Propofol was the sole sedative used." | 1.40 | Same-day bidirectional endoscopy with nonanesthesiologist administration of propofol: safety and cost-effectiveness compared with separated exams. ( Angueira, T; Arias, Á; Chumillas, O; Fernández-Fuente, M; Fernández-Ordóñez, M; González-Castillo, S; Guagnozzi, D; Lucendo, AJ; Sánchez-Cazalilla, M; Serrano-Valverde, M; Tenías, JM, 2014) |
"Cardiac arrhythmias were observed in 21 (53·8%) dogs." | 1.40 | Management and complications of anaesthesia during balloon valvuloplasty for pulmonic stenosis in dogs: 39 cases (2000 to 2012). ( Monteiro-Steagall, BP; Ramos, RV; Steagall, PV, 2014) |
"Hypotension is more common in patients with Eisenmenger syndrome and similar physiology when a vasopressor is not used during the peri-induction period, regardless of induction agent." | 1.40 | Anesthetic management and outcomes for patients with pulmonary hypertension and intracardiac shunts and Eisenmenger syndrome: a review of institutional experience. ( Bennett, JM; Eagle, SS; Ehrenfeld, JM; Markham, L, 2014) |
"Hypotension was defined when blood pressure decreased more than or equal to 25 percent compared to blood pressure measured at first in operating room." | 1.40 | [Retrospective evaluation of predictors and frequency of hypotension in hypertensive patients after induction of general anesthesia]. ( Ida, M; Iwata, M; Kamiya, T; Kimoto, K; Kuzumoto, N; Nakayama, K; Shimomura, T, 2014) |
"Propofol was commenced in all patients at a mean infusion rate of 18." | 1.38 | Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation. ( Drewitz, I; Heitmann, K; Hoffmann, BA; Rostock, T; Salukhe, TV; Steven, D; Willems, S, 2012) |
"Propofol is an intravenous anesthetic that is widely used to anesthetize patients during neurosurgical procedures." | 1.38 | Opioid receptor blockade prevents propofol-induced hypotension in rats. ( de Moura, RS; Lessa, MA; Maracajá-Neto, LF; Mello Silva, GA; Tibiriçá, E, 2012) |
"Transient respiratory depression occurred in 13." | 1.38 | Induction dose of propofol for pediatric patients undergoing procedural sedation in the emergency department. ( Christich, AC; Edwards, CJ; Jasiak, KD; Patanwala, AE; Phan, H; Skrepnek, GH, 2012) |
"Propofol was administered via intermittent i." | 1.38 | Endoscopist-administered propofol sedation is safe - a prospective evaluation of 10,000 patients in an outpatient practice. ( Friedrich, K; Sieg, A; Stremmel, W, 2012) |
"Propofol was administered by continuous intravenous infusion to achieve deep sedation." | 1.37 | Safety of continuous propofol sedation for endoscopic procedures in elderly patients. ( Aparicio, JR; Casellas, JA; Compañy, L; Gómez-Escolar, L; Martínez, JF; Mozas, I; Ruiz, F, 2011) |
"To provide data on the epidemiology of adverse events during sedation for endoscopy." | 1.37 | Adverse events during monitored anesthesia care for GI endoscopy: an 8-year experience. ( Agostoni, M; Beretta, L; Fanti, L; Gemma, M; Pasculli, N; Testoni, PA, 2011) |
"78 cases of hypoxemia were documented in 1764 patients (4." | 1.37 | Nurse-administered propofol sedation for endoscopy: a risk analysis during an implementation phase. ( Banning, A; Bodtger, U; Hammering, A; Hornslet, P; Horsted, T; Jensen, JT; Vilmann, P, 2011) |
"Propofol was given as monotherapy." | 1.37 | Nurse-administered propofol sedation for gastrointestinal endoscopic procedures: first Nordic results from implementation of a structured training program. ( Hammering, A; Hornslet, P; Mantoni, T; Slagelse, C; Vilmann, P, 2011) |
"Where hypotension was present, the method of and response to treatment was recorded." | 1.36 | A comparison of anesthetic complications between diabetic and nondiabetic dogs undergoing phacoemulsification cataract surgery: a retrospective study. ( Clark, L; Corletto, F; Gould, DJ; Oliver, JA, 2010) |
" We aimed to establish whether the duration of preoperative abstinence from fluids independently contributed to arterial blood pressure changes and dosage requirements during propofol induction." | 1.36 | The influence of duration of fluid abstinence on hypotension during propofol induction. ( Lewis, CM; Morley, AP; Nalla, BP; Natarajan, A; Prevost, AT; Strandvik, G; Vamadevan, S, 2010) |
"Hypotension is a common occurrence during defibrillator implantation under conscious sedation." | 1.35 | Predictors of hemodynamic compromise with propofol during defibrillator implantation: a single center experience. ( Dhoble, A; Gardiner, JC; Habetler, T; Holliday, J; Janes, R; Natla, J; Pandya, K; Patel, MB; Punnam, SR; Thakur, RK, 2009) |
"Propofol was administered using a standardized protocol, which included an initial dose of 0." | 1.34 | Efficacy, safety and patient satisfaction of propofol for procedural sedation and analgesia in the emergency department: a prospective study. ( Abu-Laban, RB; Chan, WW; Harrison, DW; Zed, PJ, 2007) |
" Statistically significant multivariate predictors of hypotension 0-10 min after anesthetic induction included: ASA III-V, baseline MAP <70 mm Hg, age > or =50 yr, the use of propofol for induction of anesthesia, and increasing induction dosage of fentanyl." | 1.33 | Predictors of hypotension after induction of general anesthesia. ( Baez, B; Bernstein, A; Bodian, CA; Hossain, S; Krol, M; Patel, P; Reich, DL, 2005) |
"Propofol was administered during PSA to 792 patients during the respective reporting period at each center." | 1.33 | Propofol for emergency department procedural sedation and analgesia: a tale of three centers. ( Becker, C; Burton, JH; Miner, JR; Shipley, ER; Strout, TD; Thode, HC, 2006) |
"Propofol is an effective agent for use in procedural sedation and analgesia (PSA)." | 1.33 | Propofol by infusion protocol for ED procedural sedation. ( Bigelow, SK; Fay, K; Frank, LR; Hauff, SR; Strote, J, 2006) |
"Propofol was delivered in intermittent boluses to achieve the desired level of anesthesia." | 1.31 | Prospective evaluation of propofol anesthesia in the pediatric intensive care unit for elective oncology procedures in ambulatory and hospitalized children. ( Anderson, BD; Dalton, HJ; Gootenberg, JE; Hauser, GJ; Hertzog, JH; Shad, AT, 2000) |
"Nevertheless, severe hypoxemia is an accepted contraindication to FOB in nonintubated patients." | 1.31 | Bronchoscopy with bronchoalveolar lavage via the laryngeal mask airway in high-risk hypoxemic immunosuppressed patients. ( Cardinaud, JP; Favier, JC; Gbikpi-Benissan, G; Gruson, D; Hilbert, G; Portel, L; Valentino, R; Vargas, F, 2001) |
"To determine the incidence of adverse events related to an endoscopy sedation regimen that included propofol, delivered by general practitioner (GP) sedationists." | 1.31 | Sedation for endoscopy: the safe use of propofol by general practitioner sedationists. ( Chiragakis, L; Clarke, AC; Hillman, LC; Kaye, GL, 2002) |
"Propofol anesthesia was performed successfully in all children (mean age, 6." | 1.30 | Propofol anesthesia for invasive procedures in ambulatory and hospitalized children: experience in the pediatric intensive care unit. ( Campbell, JK; Dalton, HJ; Hauser, GJ; Hertzog, JH, 1999) |
" However, marked tachycardia associated with the use of ephedrine in combination with propofol occurred in the majority of patients, occasionally reaching high levels in individual patients." | 1.30 | The haemodynamic effects of propofol in combination with ephedrine in elderly patients (ASA groups 3 and 4). ( Berridge, J; Freeman, J; Gamlin, F; Vucevic, M; Winslow, L, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (0.34) | 18.7374 |
1990's | 28 (9.62) | 18.2507 |
2000's | 65 (22.34) | 29.6817 |
2010's | 128 (43.99) | 24.3611 |
2020's | 69 (23.71) | 2.80 |
Authors | Studies |
---|---|
Yang, H | 1 |
Zhao, Q | 2 |
Chen, HY | 1 |
Liu, W | 2 |
Ding, T | 1 |
Yang, B | 1 |
Song, JC | 1 |
Aminnejad, R | 1 |
Hormati, A | 1 |
Shafiee, H | 1 |
Alemi, F | 1 |
Hormati, M | 1 |
Saeidi, M | 1 |
Ahmadpour, S | 1 |
Sabouri, SM | 1 |
Aghaali, M | 1 |
Atchley, E | 1 |
Tesoro, E | 1 |
Meyer, R | 1 |
Bauer, A | 1 |
Pulver, M | 1 |
Benken, S | 1 |
Gao, Y | 1 |
Yan, F | 1 |
Oliveira-Paula, GH | 3 |
Pereira, DA | 1 |
Pinheiro, LC | 3 |
Ferreira, GC | 3 |
Paula-Garcia, WN | 2 |
Garcia, LV | 3 |
Lacchini, R | 3 |
Luizon, MR | 1 |
Tanus-Santos, JE | 3 |
Sneyd, JR | 2 |
Absalom, AR | 1 |
Barends, CRM | 1 |
Jones, JB | 1 |
Cuniberti, B | 1 |
Huuskonen, V | 1 |
Hughes, JL | 1 |
Zeng, Y | 1 |
Wang, DX | 1 |
Lin, ZM | 1 |
Liu, J | 3 |
Wei, XC | 1 |
Deng, J | 1 |
Liu, YF | 1 |
Ma, EL | 1 |
Yang, MC | 1 |
Zheng, H | 1 |
Yu, XD | 1 |
Guo, QL | 1 |
Guan, YJ | 1 |
Hu, F | 1 |
Zou, L | 1 |
Chang, H | 3 |
Tian, L | 1 |
Liu, F | 1 |
Lan, Y | 1 |
Zhang, F | 3 |
Liu, X | 2 |
Schonberger, RB | 4 |
Dai, F | 3 |
Michel, G | 1 |
Vaughn, MT | 1 |
Burg, MM | 3 |
Mathis, M | 1 |
Kheterpal, S | 2 |
Akhtar, S | 4 |
Shah, N | 1 |
Bardia, A | 2 |
Yuan, I | 1 |
Xu, T | 1 |
Skowno, J | 1 |
Zhang, B | 1 |
Davidson, A | 1 |
von Ungern-Sternberg, BS | 1 |
Sommerfield, D | 1 |
Zhang, J | 5 |
Song, X | 1 |
Zhang, M | 1 |
Zhao, P | 3 |
Liu, H | 2 |
Jiang, Y | 2 |
Zuo, Y | 1 |
de Graaff, JC | 1 |
Vutskits, L | 1 |
Olbrecht, VA | 1 |
Szmuk, P | 1 |
Kurth, CD | 1 |
Dantino, SC | 1 |
Kleine, SA | 1 |
Smith, CK | 1 |
Smith, SM | 1 |
Zhu, X | 1 |
Seddighi, R | 1 |
Mandel, JE | 1 |
Zarfoss, EL | 1 |
Garavaglia, J | 1 |
Hayanga, JWA | 1 |
Kabulski, G | 1 |
Cao, Y | 1 |
Chi, P | 1 |
Zhou, C | 1 |
Lv, W | 1 |
Quan, Z | 1 |
Xue, FS | 2 |
Yao, Y | 1 |
Guan, J | 1 |
Liu, L | 2 |
Fu, B | 1 |
Chen, L | 1 |
Zheng, X | 1 |
Schulz, ME | 1 |
Hockenberry, JC | 1 |
Katunaric, B | 1 |
Pagel, PS | 1 |
Freed, JK | 1 |
Johnson, EG | 1 |
Weaver, SG | 1 |
Batt, KL | 1 |
Weaver, RH | 1 |
Schadler, A | 1 |
Hall, SJ | 1 |
Qi, XR | 1 |
Sun, JY | 1 |
An, LX | 1 |
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Nakao, FS | 1 |
Lenz, L | 1 |
Rohr, MR | 1 |
Ferrari, AP | 1 |
Libera, ED | 1 |
Martínez, JF | 1 |
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Reist, U | 1 |
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Yada, S | 1 |
Tashiro, C | 1 |
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Kufera, JA | 1 |
Watson, K | 1 |
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Srikureja, W | 1 |
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Fanti, L | 1 |
Gemma, M | 1 |
Pasculli, N | 1 |
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Jensen, JT | 1 |
Vilmann, P | 2 |
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Hornslet, P | 2 |
Bodtger, U | 1 |
Banning, A | 1 |
Hammering, A | 2 |
Kurer, G | 1 |
Sayfo, S | 1 |
Vakil, KP | 1 |
Alqaqa'a, A | 1 |
Flippin, H | 1 |
Bhakta, D | 1 |
Yadav, AV | 1 |
Miller, JM | 1 |
Groh, WJ | 1 |
Salukhe, TV | 1 |
Drewitz, I | 1 |
Heitmann, K | 1 |
Rostock, T | 1 |
Slagelse, C | 1 |
Mantoni, T | 1 |
Levitzky, BE | 1 |
Dumot, JA | 1 |
Wani, S | 1 |
Azar, R | 1 |
Hovis, CE | 1 |
Hovis, RM | 1 |
Cote, GA | 1 |
Hall, M | 1 |
Waldbaum, L | 1 |
Kushnir, V | 1 |
Early, D | 1 |
Mullady, DK | 1 |
Murad, F | 1 |
Edmundowicz, SA | 1 |
Jonnalagadda, SS | 1 |
von Delius, S | 1 |
Salletmaier, H | 1 |
Meining, A | 1 |
Wagenpfeil, S | 1 |
Saur, D | 1 |
Bajbouj, M | 1 |
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Schmid, RM | 1 |
Huber, W | 1 |
Maracajá-Neto, LF | 1 |
Mello Silva, GA | 1 |
de Moura, RS | 1 |
Tibiriçá, E | 1 |
Lessa, MA | 1 |
Mukawa, C | 1 |
Taniguchi, T | 1 |
Jasiak, KD | 1 |
Phan, H | 1 |
Christich, AC | 1 |
Edwards, CJ | 1 |
Skrepnek, GH | 1 |
Patanwala, AE | 1 |
Jeong, H | 1 |
Lee, SH | 1 |
Jang, EA | 1 |
Chung, SS | 1 |
Yoo, KY | 1 |
Riphaus, A | 2 |
Geist, C | 1 |
Schrader, K | 1 |
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Kuo, FC | 1 |
Yang, HY | 1 |
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Cheng, KI | 1 |
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Xu, Y | 1 |
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Celiker, V | 1 |
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Salman, MA | 1 |
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Frazee, BW | 1 |
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Baire, M | 1 |
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Huang, SY | 1 |
Wang, CC | 1 |
Chang, WK | 1 |
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Chu, CC | 1 |
Westhout, FD | 1 |
Muhonen, MG | 1 |
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Schnoor, J | 1 |
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Krishna, HM | 1 |
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Walawander, CA | 1 |
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Gamlin, F | 2 |
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Skaar, DJ | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Comparison of Esketamine-Propofol and Fentanyl-Propofol on Haemodynamics in Elderly Patients[NCT05752409] | 120 participants (Anticipated) | Interventional | 2021-10-08 | Recruiting | |||
The Study of Ciprofol for the Suppression of Cardiovascular Responses to Tracheal[NCT06095570] | Phase 4 | 150 participants (Anticipated) | Interventional | 2022-07-23 | Recruiting | ||
The Investigation of the Dose Range of Remimazolam Besylate in Different Age Groups of Adults and Its Effects on Hemodynamics[NCT06009991] | 1,876 participants (Anticipated) | Interventional | 2023-07-17 | Recruiting | |||
The Impact of Electroencephalogram (EEG) - Guided Inhalational Anesthetic Control on the Occurrence of EEG Discontinuity in Infants: A Prospective Randomized Controlled Trial[NCT05906225] | 78 participants (Anticipated) | Interventional | 2023-06-20 | Not yet recruiting | |||
EEG to Monitor Propofol Anesthetic Depth in Infants and Toddlers[NCT05701748] | 120 participants (Anticipated) | Interventional | 2023-02-03 | Recruiting | |||
Does Intravenous Lidocaine Reduce Propofol Consumption and the Side Effects of Sedation During Gastroscopy in ASA 1 and 2 Patients.[NCT05944887] | 46 participants (Actual) | Interventional | 2023-07-21 | Completed | |||
Efficacy of Oxycodone-propofol Combination Compared With a Fentanyl-propofol Combination on Conscious Sedation Effect and Early Cognitive Function During Therapeutic Endoscopic Retrograde Cholangio-pancreatography:a Prospective,Randomized, Single- Blinded[NCT03755609] | 100 participants (Anticipated) | Interventional | 2018-06-01 | Recruiting | |||
[NCT02442232] | 65 participants (Actual) | Observational | 2015-08-31 | Completed | |||
Effect of General Anesthesia With Remimazolam Versus Propofol on Postoperative Delirium in Elderly Patients[NCT06180876] | 190 participants (Anticipated) | Interventional | 2022-05-25 | Recruiting | |||
Effects of Propofol Titration at Different Speeds on Hemodynamics and Stress During General Anesthesia Induction[NCT04595591] | 276 participants (Actual) | Interventional | 2020-10-23 | Completed | |||
Observational Study to Evaluate the Pressure Recording Analytical Method Parameters in Patients Susceptible to Post-induction Hypotension Due to Hypertension, Diabetes Mellitus, Cardiovascular Risk Factors, or Major Surgery[NCT05960604] | 660 participants (Anticipated) | Observational | 2023-12-25 | Not yet recruiting | |||
Different Types of Intraoperative Hypotension and Their Association With Post-anesthesia Care Unit Recovery[NCT05671783] | 4,776 participants (Actual) | Observational | 2022-05-06 | Completed | |||
Effect of Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Elective Cesarean Section Under Spinal Anesthesia.[NCT05071794] | Phase 4 | 60 participants (Actual) | Interventional | 2021-05-01 | Completed | ||
A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05327296] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-06-30 | Recruiting | ||
A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05312385] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-04-28 | Recruiting | ||
Early Goal-Directed Sedation Compared With Standard Care in Mechanically Ventilated Critically Ill Patients: a Prospective Multicentre Randomised Controlled Trial[NCT01728558] | Phase 3 | 4,000 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
Efficacy and Safety of Remimazolam for Sedation in ICU Patients Undergoing Mechanical Ventilation: a Single Center, Randomized, Controlled, Non-inferiority Trial[NCT04815265] | Phase 4 | 488 participants (Anticipated) | Interventional | 2021-04-01 | Not yet recruiting | ||
"Ketamine / Propofol Admixture Ketofol at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial"[NCT02105415] | Phase 2/Phase 3 | 160 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
Capnography Monitoring the Hypoventilation During Bronchoscopic Sedation[NCT02848118] | 124 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
Dexmedetomidine and Brain Perfusion Monitor for Sedation of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration[NCT03521505] | Phase 4 | 50 participants (Actual) | Interventional | 2018-05-11 | Completed | ||
Target-Controlled Infusion of Propofol for Flexible Bronchoscopy Sedation: Determining the Optimal Titrating Regimen[NCT01101477] | 144 participants (Actual) | Interventional | 2010-02-28 | Terminated (stopped due to Hypoxemia(SPaO2<80%) episodes occured significantly in the arm titration by 0.5ug/ml) | |||
Dexmedetomidine vs Propofol TIVA and Interscalene Block for Shoulder Surgeries in a Beach Chair Sitting Position[NCT02469961] | Phase 4 | 50 participants (Actual) | Interventional | 2010-10-31 | Completed | ||
The Optimal Sequence in Same-day Bidirectional Endoscopy Under Deep Anesthesia Induced by Propofol Combined With Fentanyl: A Prospective Randomized Controlled ,Two Centers Trial[NCT04973878] | 544 participants (Anticipated) | Interventional | 2021-07-30 | Not yet recruiting | |||
Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Unit[NCT03194360] | 141 participants (Actual) | Observational | 2015-12-01 | Completed | |||
Preoperative Dexmedetomidine Reduces the EC50 of Propofol for Successful i-gelTM Insertion Without Muscle Relaxants[NCT02097407] | Phase 4 | 37 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
Hemodynamic Responses During Induction: Comparison of Marsh and Schnider Pharmacokinetic Models in Propofol Plasma Target-controlled Infusion[NCT01759160] | 60 participants (Actual) | Interventional | 2012-12-31 | Completed | |||
A Randomized, Controlled Trial to Compare the Efficacy and Safety Profile of a Remimazolam-alfentanil Combination With a Propofol-alfentanil Combination for ERCP[NCT04658173] | 1,000 participants (Anticipated) | Interventional | 2020-12-22 | Recruiting | |||
Respiratory Effect of the LISA (Less Invasive Surfactant Administration) Method With Sedation by Propofol Versus Absence of Sedation: Double-blind Comparative Randomized Clinical Trial.[NCT04016246] | Phase 3 | 542 participants (Anticipated) | Interventional | 2019-10-07 | Recruiting | ||
The Use of Sedation Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST): a Randomized Study Comparing Intravenous Ketamine With Sublingual 30% Glucose[NCT04409665] | Phase 1 | 60 participants (Anticipated) | Interventional | 2020-01-01 | Recruiting | ||
Dexmedetomidine for LISA Procedure in Preterm Infants: a Pilot Study[NCT04820101] | 40 participants (Anticipated) | Interventional | 2021-05-15 | Not yet recruiting | |||
Propofol Sedation During Endoscopic Retrograde Cholangiopancreatography: A Comparison Between Conventional Versus Bispectral Index Guided Approach and Effect of Diclofenac Sodium Along With Topical Pharyngeal Anaesthesia[NCT04860167] | 90 participants (Actual) | Interventional | 2018-09-10 | Completed | |||
Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy[NCT05437497] | 264 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | |||
Cardiac Autonomic Dysfunction and Perioperative Outcomes After Neurosurgery[NCT05230641] | 400 participants (Actual) | Observational | 2022-03-01 | Completed | |||
Correlation Between Perioperative Autonomic Function and Adverse Events Such as Post-induction Hypotension in Elderly Patients[NCT05425147] | 180 participants (Anticipated) | Observational | 2022-06-11 | Recruiting | |||
Cerebral Blood Flow During Propofol Anaesthesia[NCT02951273] | 30 participants (Actual) | Observational | 2016-12-08 | Completed | |||
The Effect of Phenylephrine Versus Ephedrine on Cerebral Perfusion During Carotid Endarterectomy[NCT01451294] | 40 participants (Anticipated) | Interventional | 2011-11-30 | Not yet recruiting | |||
Influence of Vasopressors on Brain Oxygenation and Microcirculation in Anesthetized Patients With Cerebral Tumors[NCT02713087] | Phase 4 | 48 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
Comparison of Intubation Conditions After Induction With Propofol Associated With a Dose of Remifentanil or Sufentanil in Surgical Tooth Extraction.[NCT01910285] | Phase 4 | 70 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
Evaluation of the Changes of Pleth Variability Index During Preoxygenation for Predicting Hypotension During Induction of Anesthesia in Surgical Patients; Prospective Observational Study[NCT04991220] | 96 participants (Anticipated) | Interventional | 2021-08-30 | Not yet recruiting | |||
Evaluation of Perfusion Index-derived Parameters as Predictors of Hypotension After Induction of General Anaesthesia: a Prospective Cohort Study.[NCT04217226] | 93 participants (Actual) | Observational | 2020-01-20 | Completed | |||
Comparison of Ultrasound-based Measures of Inferior Vena Cava and Plethysmographic Variability Index for Prediction of Hypotension During Induction of General Anesthesia; Prospective Cohort Study.[NCT04238234] | 90 participants (Anticipated) | Observational | 2021-08-05 | Recruiting | |||
Focussed Echocardiography to Detect Preoperative Hypovolemia and Left Ventricular Dysfunction as a Predictor of Post-Induction Hypotension[NCT02944266] | 150 participants (Anticipated) | Observational | 2016-01-31 | Recruiting | |||
Predictability of Hemodynamic Instability With Increase in Perfusion Index (PI) and Pleth Variability Index (PVI) Values After Spinal Block in Elective Cesarean Sections[NCT05174260] | 113 participants (Actual) | Observational [Patient Registry] | 2021-12-02 | Completed | |||
An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia[NCT04235894] | 124 participants (Actual) | Observational | 2016-09-07 | Completed | |||
Dexmedetomidine Compared to Midazolam for Symptom Control in Advanced Cancer Patients: A Pilot Randomized Controlled Trial (RCT)[NCT01687751] | Phase 2 | 0 participants (Actual) | Interventional | 2012-11-30 | Withdrawn (stopped due to Study design determined to be not likely feasible) | ||
Ciprofol vs Propofol for Reducing Hypoxia Incidence in Intravenous Anesthesia During Elective Endoscopic Retrograde Cholangiopancreatography-A Randomized Double Blinded Controlled Trial.[NCT06015074] | 124 participants (Anticipated) | Interventional | 2023-10-01 | Not yet recruiting | |||
Nasal Inhalation of Sevoflurane Versus Midazolm,Ketamine and Propofol For Pediatric Undergoing Upper Gastrointestinal Endoscopy[NCT05474937] | 74 participants (Anticipated) | Interventional | 2022-06-01 | Recruiting | |||
Nurse Administered Propofol Sedation vs. Standard Therapy for Colonoscopy in Patients With IBD. A Randomised Controlled Study on Satisfaction and Adherence to Treatment Program.[NCT01934088] | Phase 4 | 130 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
High Flow Nasal Cannula (HFNC) Versus Standard Low Flow Nasal Cannula (LFNC) in Patients With Atrial Fibrillation Undergoing Radiofrequency Catheter Ablation (RFCA) Under Deep Desaturation.[NCT04842253] | 210 participants (Anticipated) | Interventional | 2022-01-04 | Recruiting | |||
A Pilot Study to Investigate the Efficacy and Safety of Dexmedetomidine and Fentanyl Versus Midazolam and Remifentanil for Sedation in Patients Undergoing Ablation Procedures for Treatment of a Tachyarrhythmia[NCT03451227] | 6 participants (Actual) | Interventional | 2017-12-01 | Terminated (stopped due to Unable to recruit eligible participants) | |||
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures[NCT03529461] | 56 participants (Actual) | Interventional | 2017-04-25 | Completed | |||
Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial[NCT03453359] | 180 participants (Actual) | Interventional | 2018-01-28 | Completed | |||
Comparison of Leg Elevation and Leg Wrapping in the Prevention of Propofol Induced Hypotension: A Prospective Randomised Controlled Study[NCT02845921] | 150 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | |||
Comparison of the Effects of Total Intravenous Anesthesia and Inhalation Anesthesia on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and the Mechanism Involved: a Single-center, Randomized, Prospective Study[NCT03193710] | 260 participants (Anticipated) | Observational | 2017-09-01 | Recruiting | |||
Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure[NCT02684019] | Phase 3 | 60 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
[NCT00848861] | 92 participants (Actual) | Interventional | 2006-02-28 | Completed | |||
Comparison of Ketamine-propofol Sedation Protocols With Fentanyl-propofol Administered by Endoscopist or Anesthesiologist at Colonoscopy[NCT03607110] | 120 participants (Actual) | Observational | 2018-03-01 | Completed | |||
Effect of Dexmedetomidine of Gastrointestinal Motility[NCT04798482] | Phase 4 | 22 participants (Actual) | Interventional | 2021-09-14 | Completed | ||
[NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
Comparative Study Between Intravenous Nalbuphine Versus Intravenous Dexmedetomidine for Conscious Sedation in Patients Undergoing Colonoscopy[NCT05689242] | Phase 4 | 66 participants (Anticipated) | Interventional | 2023-03-31 | Not yet recruiting | ||
"Haemodynamic Stability During Induction of General Anesthesia With Propofol and Remifentanil: A Randomized, Controlled, Double-blind Study Comparing Equipotent Prophylactic Doses of Ephedrine, Phenylephrine, Norepinephrine vs Placebo."[NCT03864094] | Phase 4 | 99 participants (Anticipated) | Interventional | 2022-03-15 | Recruiting | ||
Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia[NCT02489019] | Phase 2/Phase 3 | 105 participants (Anticipated) | Interventional | 2018-02-19 | Recruiting | ||
Perfusion Index as a Predictor of Hypotension Following Propofol Induction of General Anesthesia in Geriatric Patients - A Prospective Observational Study.[NCT04682717] | 30 participants (Actual) | Observational | 2020-12-01 | Completed | |||
Effect of the Pneumatic Compression of Lower Leg on Post-induction Hypotension in Elderly Patients Undergoing Robot Assisted Laparoscopic Prostatectomy: a Double Blined Randomized Controlled Trial[NCT05343689] | 100 participants (Actual) | Interventional | 2022-05-04 | Completed | |||
"PGDT With the Hypotension Prediction Index to Reduce the Number and Duration of Intraoperative Hypotension and the Incidence of Renal Failure in Patients Undergoing Lung Surgery"[NCT04149314] | 142 participants (Actual) | Interventional | 2019-11-20 | Completed | |||
Incidence of Sedation Related Complications With Propofol Alone Versus Propofol With Benzodiazepines and Opiates in a High Risk Group Undergoing Advanced Endoscopic Procedures: A Randomized Controlled Trial[NCT01315158] | 36 participants (Actual) | Interventional | 2011-01-31 | Terminated (stopped due to - The research team is not able to obtain the necessary support to continue the study.) | |||
A Psychomotor Recuperation Study After Deep Sedation for Colonoscopy Between Target Controlled and Manual Titration of Propofol.[NCT02314559] | Phase 4 | 164 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
Combination Ketamine and Propofol vs Propofol for Emergency Department Sedation: A Prospective Randomized Trial[NCT01269307] | 99 participants (Actual) | Interventional | 2010-06-30 | Completed | |||
Phase II Study, Randomized, Monocentric, Single-blind, Comparing the Efficacy of Xenon and Desflurane, in Association With a Thoracic Epidural Analgesia in the Maintenance Phase of a Colorectal Oncologic Surgery[NCT01696630] | Phase 2 | 31 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
Safety and Efficacy of Propofol Only Sedation in Oral and Maxillofacial Surgery[NCT01227174] | Phase 4 | 169 participants (Anticipated) | Interventional | 2011-01-31 | Not yet recruiting | ||
Effect of Ringer Lactate Preloading on Induction Dose Requirement of Propofol and Its Haemodynamic Stability at a Tertiary Center[NCT05777135] | Phase 4 | 60 participants (Anticipated) | Interventional | 2023-04-01 | Recruiting | ||
Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
comparison of intensive care unit free days between the two groups (NCT02105415)
Timeframe: hospital discharge or day 28, whichever comes first
Intervention | days (Median) |
---|---|
Etomidate | 16 |
Ketamine / Propofol Admixture | 17 |
comparison of mechanical ventilation free days between the two groups (NCT02105415)
Timeframe: hospital discharge or day 28, whichever comes first
Intervention | days (Median) |
---|---|
Etomidate | 22 |
Ketamine / Propofol Admixture | 20 |
In-hospital/28 day mortality among patients in ketamine/propofol combination compared to in-hospital/28-day mortality in etomidate. (NCT02105415)
Timeframe: Hospital Discharge or Day 28, whichever comes first
Intervention | Participants (Count of Participants) |
---|---|
Etomidate | 26 |
Ketamine / Propofol Admixture | 25 |
Comparison of number of participants who were positive for delirium using CAM-ICU between groups (NCT02105415)
Timeframe: up to 24 hours post study drug administration
Intervention | Participants (Count of Participants) |
---|---|
Etomidate | 7 |
Ketamine / Propofol Admixture | 4 |
Incidence of adrenal insufficiency between ketamine/propofol admixture and etomidate. Adrenal insuffiency was evaluated with co-syntropin stimulation test. (NCT02105415)
Timeframe: up to 24 hours post study drug administration
Intervention | Participants (Count of Participants) |
---|---|
Etomidate (3-5 Hours) | 13 |
Ketamine/Propofol Admixture (3-5 Hours) | 5 |
Etomidate (23-25 Hours) | 9 |
Ketamine/Propofol Admixture (23-25 Hours) | 6 |
blood product transfusions [Red Blood Cells vs. non-Red Blood Cells] between the two groups (NCT02105415)
Timeframe: hospital discharge or day 28, whichever comes first
Intervention | Participants (Count of Participants) | ||
---|---|---|---|
Red blood cell | Non-red blood cell | Colloid | |
Etomidate | 21 | 16 | 28 |
Ketamine / Propofol Admixture | 13 | 8 | 26 |
Mean arterial pressure for the ketamine/propofol group at a 1:1 dose ratio compared to the etomidate group within the first 15 minutes post-administration in patients in need of urgent and/or emergent endotracheal intubation, as defined by any intubation within the intensive care unit excluding intubations for elective procedural events and codes. (NCT02105415)
Timeframe: baseline and every 5 minutes up to 15 minutes minutes post study drug administration
Intervention | mm Hg (Mean) | |||
---|---|---|---|---|
Baseline | 5 minutes | 10 minutes | 15 minutes | |
Etomidate | 82.8 | 81.7 | 81.9 | 79.1 |
Ketamine / Propofol Admixture | 80.9 | 77.6 | 75.3 | 75.5 |
The use of vasoactive medications to restore the blood pressure post-administration in the ketamine/propofol combination as compared to the etomidate group. (NCT02105415)
Timeframe: up to 24 hours post study drug administration
Intervention | Participants (Count of Participants) | ||
---|---|---|---|
Pre-treament | New-onset pressors (within 3 minutes) | Delayed-onset pressors (within 24 hours) | |
Etomidate | 1 | 12 | 57 |
Ketamine / Propofol Admixture | 5 | 18 | 64 |
The percentage of patients with bradycardia (heat beat per minute less than 60) (NCT03521505)
Timeframe: After starting sedation, up to 120 minutes.
Intervention | Participants (Count of Participants) |
---|---|
Dexmedetomidine Arm | 12 |
Propofol Arm | 4 |
The percentage of patients with hypotension (mean arterial blood pressure (MAP) less than 65 mmHg with any duration. (NCT03521505)
Timeframe: After starting sedation, up to 120 minutes.
Intervention | Participants (Count of Participants) |
---|---|
Dexmedetomidine Arm | 1 |
Propofol Arm | 5 |
The percentage of patients with hypoxemia (oxyhemoglobin saturation (SpO2)<90%) during induction of bronchoscopic sedation (NCT03521505)
Timeframe: After starting induction, up to 30 minutes.
Intervention | Participants (Count of Participants) |
---|---|
Dexmedetomidine Arm | 1 |
Propofol Arm | 2 |
The percentage of patients with hypoxemia (oxyhemoglobin saturation (SpO2)<90%) during maintenance of Bronchoscopic sedation (NCT03521505)
Timeframe: After starting bronchoscopy, up to 120 minutes
Intervention | Participants (Count of Participants) |
---|---|
Dexmedetomidine Arm | 8 |
Propofol Arm | 14 |
The procedure time of bronchoscopy and recovery time from sedation to awake. (NCT03521505)
Timeframe: After starting bronchoscopy, up to 120 minutes.
Intervention | minutes (Mean) |
---|---|
Dexmedetomidine Arm | 30.0 |
Propofol Arm | 27.6 |
The Cooperation of Patients will be evaluated by 100-mm visual analogue scale (VAS, 0: well cooperation, 100: worst cooperation) after recovery. (NCT03521505)
Timeframe: After recovery from sedation, up to 120 minutes
Intervention | units on a scale (Median) |
---|---|
Dexmedetomidine Arm | 14 |
Propofol Arm | 31 |
The Global Tolerance of patients for bronchoscopy will be evaluated by 100-mm visual analogue scale (VAS, 0: no bother, 100: worst intolerable) after recovery (NCT03521505)
Timeframe: After recovery from sedation, up to 120 minutes
Intervention | units on a scale (Median) |
---|---|
Dexmedetomidine Arm | 12.5 |
Propofol Arm | 0 |
"Hypoxemia is defined as:~Oxyhemoglobin saturation (SPO2) is less than 90 % with any duration" (NCT01101477)
Timeframe: During sedative induction and bronchoscopy
Intervention | participants (Number) |
---|---|
Titration by Target Effect Site Concentration (Cet) 0.5μg/ml | 29 |
Titration by Cet 0.2μg/ml | 22 |
Titration by Cet 0.1μg/ml | 18 |
Number of participants observed with Bradycardia or Hypotension who required intervention (NCT02469961)
Timeframe: Participants will be followed from the start of sedation until discharge: approximately 3-5 hr
Intervention | participants (Number) |
---|---|
Propofol | 4 |
Dexmedetomidine | 5 |
airway manipulation or repositioning: apnea, oral airway, adjust head (NCT02469961)
Timeframe: Participants will be followed from the start of sedation until discharge: approximately 3-5 hr
Intervention | participants (Number) |
---|---|
Dexmedetomidine | 0 |
Propofol | 5 |
length of stay in minutes in the Post Anesthesia Care Unit before discharge (NCT02469961)
Timeframe: Arrival in the PACU until discharge either to home or to a hospital in-patient bed approximately 1-3 hr after the operation
Intervention | Minutes (Mean) |
---|---|
Dexmedetomidine | 159 |
Propofol | 126 |
the use for morphine and/or fentanyl and or Demerol converted to morphine equivalents (NCT02469961)
Timeframe: Participants will be followed from the start of sedation until discharge: approximately 3-5 hr
Intervention | Microgram (Mean) |
---|---|
Dexmedetomidine | 7.1 |
Propofol | 9 |
After propofol infusion started, according to sedation level, TCI targets were gradually titrated to reach a state of equilibrium at the end of the first 25 minutes. SVI were continuously monitored, at the end of the first 25 minutes, value change from baseline level were calculated. (NCT01759160)
Timeframe: The end of the first 25 minutes after propofol infusion
Intervention | ml/beat/m^2 (Mean) |
---|---|
Marsh | -31.1 |
Schnider | -31.7 |
"Association by multiple regression between changes in unilateral internal carotid artery blood flow [ml/min] as outcome variable and changes in mean arterial pressure [mmHg] and cardiac output [l/min] as covariates.~Internal carotid artery blood flow [ml/min] was assessed by duplex ultrasound. Mean arterial pressure [mmHg] was recorded by a transducer connected to an arterial line. Cardiac output [l/min] was evaluated by pulse contour analysis (Modelflow) that estimates cardiac output by analysis of the arterial pressure curve taking age, gender, height and weigth into account." (NCT02951273)
Timeframe: Two measurements; one measurement during anaesthesia-induced hypotension (mean arterial pressure < 65 mmHg) before administration of phenylephrine and one measurement 3-5 min after administration of phenylephrine.
Intervention | ml/min (Least Squares Mean) |
---|---|
Study of Cerebral Blood Flow | 376 |
Cardiac output [l/min] as evaluated continuously by pulse contour analysis of the arterial pressure curve (Modelflow). (NCT02951273)
Timeframe: Continuous measurements from before induction of anaesthesia and until 2 hours after start of surgery.
Intervention | l/min (Mean) |
---|---|
Study of Cerebral Blood Flow | -2.7 |
Forehead skin blood flow [PU] assessed by laser Doppler flowmetry as compared between those patients who develop mesenteric traction syndrome (defined as flushing within 60 min after the start of surgery) and those who do not. Laser Doppler flowmetry applies a laser placed on the forehead that penetrates the skin and is scattered with a Doppler shift by the red blood cells and return to a detector that evaluates the amount of backscattered light and Doppler shift. An effect of a MTS was evaluated by a repeated measure mixed model with the fixed effects time point, group according to development of MTS, and interaction between time and group. The reported result is the interaction factor for the time point 0 min after flushing and 20 min after the start of surgery in patients who did not develop MTS. (NCT02951273)
Timeframe: Six measurements during anaesthesia; 5 min before and after incision and 0, 20, 40, and 70 min after flushing and 20, 40, 60, and 90 min after the start of surgery in those patients who do not develop mesenteric traction syndrome.
Intervention | PU (Mean) |
---|---|
Study of Cerebral Blood Flow | 126 |
Forehead skin oxygenation [%] assessed by laser Doppler flowmetry as compared between those patients who develop a MTS (defined as flushing within 60 min after the start of surgery) and those who do not. An effect of a MTS was evaluated by a repeated measure mixed model with the fixed effects time point, group according to development of MTS, and interaction between time and group. The reported result is the interaction factor for the time point 0 min after flushing and 20 min after the start of surgery in patients who did not develop MTS. (NCT02951273)
Timeframe: Six measurements during anaesthesia; 5 min before and after incision and 0, 20, 40, and 70 min after flushing and 20, 40, 60, and 90 min after the start of surgery in those patients who do not develop mesenteric traction syndrome.
Intervention | oxygenation [%] (Mean) |
---|---|
Study of Cerebral Blood Flow | -2 |
Near-infrared spectroscopy determined frontal lobe oxygenation [%] as compared between those patients who develop a MTS (defined as flushing within 60 min after the start of surgery) and those who do not. An effect of a MTS was evaluated by a repeated measure mixed model with the fixed effects time point, group according to development of MTS, and interaction between time and group. The reported result is the interaction factor for the time point 0 min after flushing and 20 min after the start of surgery in patients who did not develop MTS. (NCT02951273)
Timeframe: Six measurements during anaesthesia; 5 min before and after incision and 0, 20, 40, and 70 min after flushing and 20, 40, 60, and 90 min after the start of surgery in those patients who do not develop mesenteric traction syndrome.
Intervention | oxygenation [%] (Mean) |
---|---|
Study of Cerebral Blood Flow | 2 |
Heart rate [bpm] as recorded continuously by a transducer connected to an arterial line. (NCT02951273)
Timeframe: Continuous measurements from before induction of anaesthesia and until 2 hours after start of surgery.
Intervention | beats/min (Mean) |
---|---|
Study of Cerebral Blood Flow | -13 |
Unilateral internal carotid artery blood flow [ml/min] assessed by duplex ultrasound as compared between those patients who develop a MTS (defined as flushing within 60 min after the start of surgery) and those who do not. An effect of a MTS was evaluated by a repeated measure mixed model with the fixed effects time point, group according to development of MTS, and interaction between time and group. The reported result is the interaction factor for the time point 0 min after flushing and 20 min after the start of surgery in patients who did not develop MTS. (NCT02951273)
Timeframe: Six measurements during anaesthesia; 5 min before and after incision and 0, 20, 40, and 70 min after flushing and 20, 40, 60, and 90 min after the start of surgery in those patients who do not develop mesenteric traction syndrome.
Intervention | ml/min (Mean) |
---|---|
Study of Cerebral Blood Flow | -3 |
Unilateral internal carotid artery blood flow [ml/min] assessed by duplex ultrasound. (NCT02951273)
Timeframe: Two measurements; one measurement 5-10 min before induction of anaesthesia and one measurement 5-20 min after induction of anaesthesia.
Intervention | ml/min (Mean) |
---|---|
Study of Cerebral Blood Flow | -144 |
Unilateral internal carotid artery blood flow [ml/min] assessed by duplex ultrasound. (NCT02951273)
Timeframe: Two measurements; one measurement during anaesthesia-induced hypotension (mean arterial pressure < 65 mmHg) before administration of phenylephrine and one measurement 3-5 min after administration of phenylephrine.
Intervention | ml/min (Mean) |
---|---|
Study of Cerebral Blood Flow | 27 |
Mean arterial pressure [mmHg] as recorded continuously by a transducer connected to an arterial line. (NCT02951273)
Timeframe: Continuous measurements from before induction of anaesthesia and until 2 hours after start of surgery.
Intervention | mmHg (Mean) |
---|---|
Study of Cerebral Blood Flow | -41 |
Stroke volume [ml] as evaluated continuously by pulse contour analysis of the arterial pressure curve (Modelflow). (NCT02951273)
Timeframe: Continuous measurements from before induction of anaesthesia and until 2 hours after start of surgery.
Intervention | ml (Mean) |
---|---|
Study of Cerebral Blood Flow | -24 |
"Unilateral internal carotid artery blood flow [ml/min] assessed by duplex ultrasound and arterial CO2 tension (PaCO2) [kPa] was evaluated by gas analysis. Changes in PaCO2 are guided by evaluation of end-tidal CO2 tension.~The CO2 reactivity to hypocapnia when awake and during anaesthesia is calculated as the percentage change in internal carotid artery blood flow per kPa change in PaCO2. The CO2 reactivity when awake and when anaesthetized is compared." (NCT02951273)
Timeframe: Four measurements; before induction of anaesthesia during normoventilation and during hyperventilation to reduce PaCO2 by 1.5 kPa and during anaesthesia at a PaCO2 at the value before induction of anaesthesia and 1.5 kPa below that value.
Intervention | %/kPa (Mean) |
---|---|
Study of Cerebral Blood Flow | 7.4 |
We used non-invasive positive pressure ventilation (NIPPV) as a first rescue maneuver in control patients who developed an oxygen desaturation less than 90 % and reported on the percentage of participants who responded. The rescue was considered successful with recovery of oxygen saturation more than 90 % within 3 minutes. (NCT03529461)
Timeframe: 3 minutes following a desaturation event < 90 %
Intervention | Participants (Count of Participants) |
---|---|
Control Participants With Oxygen Desaturation < 90% | 8 |
Percentage of participants who develop a peripheral oxygen saturation event < 90%. (NCT03529461)
Timeframe: Time in seconds beginning with the start of procedure (anesthesia induction) ending with procedure completion (eyes open to verbal stimuli).
Intervention | percentage of participants (Number) |
---|---|
Control | 28.6 |
Experimental | 3.5 |
Percentage of participants who develop a peripheral oxygen saturation measured by pulse oximetry ≤ 94% (NCT03529461)
Timeframe: Time in seconds beginning with the start of procedure (anesthesia induction) ending with procedure completion (eyes open to verbal stimuli).
Intervention | percentage of participants (Number) |
---|---|
Control | 57.1 |
Experimental | 14.3 |
In high risk patients (meeting at least of 1 of 3 criteria: ASA ≥ 3, BMI ≥ 30, those at risk for OSA) undergoing advanced endoscopy procedures, compare the number of participants who experience airway maneuvers (AMs) when sedated with propofol alone versus propofol in combination with benzodiazepines and opioids. (NCT01315158)
Timeframe: One day (during procedure)
Intervention | participants (Number) |
---|---|
Propofol+Benzo/Opioids | 4 |
Propofol Alone | 4 |
Compare the number of participants who experience other sedation related complications such as hypotension, hypoxemia and need for termination of the procedure between the two groups (NCT01315158)
Timeframe: One day (during procedure)
Intervention | participants (Number) |
---|---|
Propofol+Benzo/Opioids | 0 |
Propofol Alone | 0 |
The number of participants who experience symptoms of nausea and vomiting in the two groups of patients will be recorded. This will be recorded during the follow-up phone call made 24-48 hours after the procedure. (NCT01315158)
Timeframe: 24-48 hours
Intervention | participants (Number) |
---|---|
Propofol+Benzo/Opioids | 2 |
Propofol Alone | 1 |
(NCT01315158)
Timeframe: One year
Intervention | incidences (Number) |
---|---|
Propofol+Benzo/Opioids | 0 |
Propofol Alone | 0 |
(NCT01315158)
Timeframe: One year
Intervention | incidences (Number) |
---|---|
Propofol+Benzo/Opioids | 0 |
Propofol Alone | 0 |
(NCT01315158)
Timeframe: One year
Intervention | incidences (Number) |
---|---|
Propofol+Benzo/Opioids | 0 |
Propofol Alone | 0 |
(NCT01315158)
Timeframe: One year
Intervention | participants (Number) |
---|---|
Propofol+Benzo/Opioids | 0 |
Propofol Alone | 0 |
23 reviews available for propofol and Hypotension
Article | Year |
---|---|
Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis.
Topics: Colonoscopy; Humans; Hypnotics and Sedatives; Hypotension; Midazolam; Propofol; Retrospective Studie | 2022 |
Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis.
Topics: Colonoscopy; Humans; Hypnotics and Sedatives; Hypotension; Midazolam; Propofol; Retrospective Studie | 2022 |
Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis.
Topics: Colonoscopy; Humans; Hypnotics and Sedatives; Hypotension; Midazolam; Propofol; Retrospective Studie | 2022 |
Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis.
Topics: Colonoscopy; Humans; Hypnotics and Sedatives; Hypotension; Midazolam; Propofol; Retrospective Studie | 2022 |
Remimazolam versus propofol for procedural sedation and anesthesia: a systemic review and meta-analysis.
Topics: Anesthesia, General; Benzodiazepines; Humans; Hypnotics and Sedatives; Hypotension; Propofol | 2022 |
Comparison of remimazolam and propofol about safety outcome indicators during general anesthesia in surgical patients: a systematic review and meta-analysis.
Topics: Anesthesia, General; Benzodiazepines; Dizziness; Humans; Hypnotics and Sedatives; Hypotension; Hypox | 2023 |
Remimazolam
Topics: Anesthesia; Benzodiazepines; Bradycardia; Conscious Sedation; Dizziness; Humans; Hypotension; Pain; | 2023 |
Safety and efficacy of propofol alone or in combination with other agents for sedation of patients undergoing colonoscopy: an updated meta-analysis.
Topics: Apnea; Colonoscopy; Deep Sedation; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Hypot | 2020 |
Comparison of clinical efficacy and safety between dexmedetomidine and propofol among patients undergoing gastrointestinal endoscopy: a meta-analysis.
Topics: Dexmedetomidine; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Hypotension; Propofol | 2021 |
Comparison of bolus versus continuous infusion of propofol for procedural sedation: a meta-analysis.
Topics: Anesthesia; Humans; Hypnotics and Sedatives; Hypotension; Propofol; Randomized Controlled Trials as | 2017 |
Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 2018 |
Moderate and deep sedation training and pharmacology for nonanesthesiologists: recommendations for effective practice.
Topics: Administration, Intravenous; Analgesics, Opioid; Anesthesiology; Apnea; Benzodiazepines; Conscious S | 2019 |
Propofol versus midazolam for upper gastrointestinal endoscopy in cirrhotic patients: a meta-analysis of randomized controlled trials.
Topics: Anesthesia Recovery Period; Bradycardia; Deep Sedation; Endoscopy, Gastrointestinal; Fibrosis; Hepat | 2015 |
Anaesthetic and sedative agents used for electrical cardioversion.
Topics: Anesthetics; Apnea; Diazepam; Electric Countershock; Etomidate; Fentanyl; Humans; Hypnotics and Seda | 2015 |
What Works and What's Safe in Pediatric Emergency Procedural Sedation: An Overview of Reviews.
Topics: Anesthetics, Intravenous; Child; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Hypote | 2016 |
Propofol for Treatment of Refractory Alcohol Withdrawal Syndrome: A Review of the Literature.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Alcohol-Induced Disorders, Nervous System; Bradycardia; | 2016 |
Similar Risk of Cardiopulmonary Adverse Events Between Propofol and Traditional Anesthesia for Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis.
Topics: Anesthesia; Anesthetics, Intravenous; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Humans; Hyp | 2017 |
The Comparison of Etomidate and Propofol Anesthesia in Patients Undergoing Gastrointestinal Endoscopy: A Systematic Review and Meta-Analysis.
Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Arterial Pressure; Colonoscopy; Endosco | 2017 |
Propofol infusion syndrome: a rare complication with potentially fatal results.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Critical Care; | 2008 |
Clinical effects and lethal and forensic aspects of propofol.
Topics: Accidents; Acidosis; Acute Kidney Injury; Bacteremia; Bradycardia; Drug Overdose; Dyslipidemias; For | 2011 |
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma | 2013 |
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma | 2013 |
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma | 2013 |
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma | 2013 |
The safe and effective use of propofol sedation in children undergoing diagnostic and therapeutic procedures: experience in a pediatric ICU and a review of the literature.
Topics: Child; Diagnosis; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units, Pediatric; Len | 2003 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Reports of death with use of propofol (Diprivan) for nonprocedural (long-term) sedation and literature review.
Topics: Acidosis; Adult; Adverse Drug Reaction Reporting Systems; Cardiovascular System; Child; Humans; Hypn | 2006 |
Propofol for sedation in the intensive care unit: essentials for the clinician.
Topics: Adult; Aged; Apnea; Bradycardia; Critical Care; Drug Administration Schedule; Half-Life; Humans; Hyp | 1997 |
Propofol toxicity in critically ill pediatric patients: show us the proof.
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Bradycardia; Child; Child, Preschool; Conscious Sedation | 1998 |
127 trials available for propofol and Hypotension
Article | Year |
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The median effective concentration of propofol with different doses of esketamine during gastrointestinal endoscopy in elderly patients: A randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Hypote | 2022 |
Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial.
Topics: Apnea; Colonoscopy; Dexmedetomidine; Double-Blind Method; Fentanyl; Humans; Hypnotics and Sedatives; | 2022 |
Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery.
Topics: Anesthesia; Apnea; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Hypotension; Hypo | 2022 |
Comparison between continuous rate infusion and target-controlled infusion of propofol in dogs: a randomized clinical trial.
Topics: Anesthetics, Intravenous; Animals; Apnea; Dog Diseases; Dogs; Hypotension; Propofol; Prospective Stu | 2023 |
Efficacy and safety of HSK3486 for the induction and maintenance of general anesthesia in elective surgical patients: a multicenter, randomized, open-label, propofol-controlled phase 2 clinical trial.
Topics: Anesthesia, General; Anesthetics, Intravenous; Elective Surgical Procedures; Humans; Hypotension; Pr | 2022 |
Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study.
Topics: Benzodiazepines; China; Gastroscopy; Humans; Hypnotics and Sedatives; Hypotension; Liver Cirrhosis; | 2022 |
Discharge readiness after remimazolam versus propofol for colonoscopy: A randomised, double-blind trial.
Topics: Adult; Benzodiazepines; Bradycardia; Colonoscopy; Humans; Hypnotics and Sedatives; Hypotension; Mida | 2022 |
Effects of intravenous lidocaine on hypoxemia induced by propofol-based sedation for gastrointestinal endoscopy procedures: study protocol for a prospective, randomized, controlled trial.
Topics: Conscious Sedation; Endoscopy, Gastrointestinal; Humans; Hypotension; Hypoxia; Lidocaine; Midazolam; | 2022 |
Effect of different doses of esketamine compared with fentanyl combined with propofol on hypotension in patients undergoing painless abortion surgery: a prospective, randomized, double-blind controlled clinical trial.
Topics: Analgesics; Anesthetics, Intravenous; Double-Blind Method; Female; Fentanyl; Humans; Hypotension; Ke | 2022 |
Hypotension after general anesthesia induction using remimazolam in geriatric patients: Protocol for a double-blind randomized controlled trial.
Topics: Aged; Anesthesia, General; Benzodiazepines; Double-Blind Method; Humans; Hypnotics and Sedatives; Hy | 2022 |
Remimazolam versus propofol for deep sedation/anaesthesia in upper gastrointestinal endoscopy in elderly patients: A multicenter, randomized controlled trial.
Topics: Aged; Anesthesia; Benzodiazepines; Bradycardia; Deep Sedation; Endoscopy, Gastrointestinal; Female; | 2022 |
Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy.
Topics: Benzodiazepines; Dizziness; Female; Humans; Hypnotics and Sedatives; Hypotension; Hysteroscopy; Naus | 2022 |
Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy.
Topics: Benzodiazepines; Dizziness; Female; Humans; Hypnotics and Sedatives; Hypotension; Hysteroscopy; Naus | 2022 |
Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy.
Topics: Benzodiazepines; Dizziness; Female; Humans; Hypnotics and Sedatives; Hypotension; Hysteroscopy; Naus | 2022 |
Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy.
Topics: Benzodiazepines; Dizziness; Female; Humans; Hypnotics and Sedatives; Hypotension; Hysteroscopy; Naus | 2022 |
A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial.
Topics: Alfentanil; Anesthetics, Intravenous; Bradycardia; Dizziness; Gastroscopy; Humans; Hypotension; Hypo | 2023 |
A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial.
Topics: Alfentanil; Anesthetics, Intravenous; Bradycardia; Dizziness; Gastroscopy; Humans; Hypotension; Hypo | 2023 |
A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial.
Topics: Alfentanil; Anesthetics, Intravenous; Bradycardia; Dizziness; Gastroscopy; Humans; Hypotension; Hypo | 2023 |
A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial.
Topics: Alfentanil; Anesthetics, Intravenous; Bradycardia; Dizziness; Gastroscopy; Humans; Hypotension; Hypo | 2023 |
Comparison of hemodynamics during induction of general anesthesia with remimazolam and target-controlled propofol in middle-aged and elderly patients: a single-center, randomized, controlled trial.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Hemodynamics; Humans; Hypotension; Middl | 2023 |
A randomized, controlled clinical trial comparing remimazolam to propofol when combined with alfentanil for sedation during ERCP procedures.
Topics: Alfentanil; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Humans; Hypnotics a | 2023 |
Safety and tolerability of esketamine in propofol based sedation for endoscopic variceal ligation with or without injection sclerotherapy: Randomized controlled trial.
Topics: Humans; Hypotension; Ketamine; Propofol; Sclerotherapy | 2023 |
Clinical effect of different doses of ciprofol for induction of general anesthesia in elderly patients: A randomized, controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Humans; Hypotension; Propofol; Receptors, GABA- | 2023 |
Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Emergence Delirium; Fentany | 2023 |
Cardiopulmonary Adverse Events of Remimazolam versus Propofol During Cervical Conization: A Randomized Controlled Trial.
Topics: Alfentanil; Anesthetics, Intravenous; Benzodiazepines; Bradycardia; Conization; Humans; Hypotension; | 2023 |
Efficacy and safety of remimazolam tosilate versus propofol in patients undergoing day surgery: a prospective randomized controlled trial.
Topics: Ambulatory Surgical Procedures; Flumazenil; Humans; Hypotension; Pain; Propofol; Prospective Studies | 2023 |
Hemodynamic effects of a low versus a high dose of propofol during induction of anesthesia. A randomized trial.
Topics: Anesthesia, General; Anesthetics, Intravenous; Female; Hemodynamics; Humans; Hypotension; Propofol; | 2023 |
Post-induction hypotension with remimazolam versus propofol in patients routinely administered angiotensin axis blockades: a randomized control trial.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Benzodiazepines; Female; Humans | 2023 |
Efficacy of Isoflurane-Remifentanil versus Propofol-Remifentanil on Controlled Hypotension and Surgeon Satisfaction in Rhinoplasty: A Single-Blind Clinical Trial Study.
Topics: Anesthetics, Intravenous; Child; Humans; Hypotension; Hypotension, Controlled; Isoflurane; Personal | 2023 |
Effectiveness of remimazolam besylate combined with alfentanil for fiberoptic bronchoscopy with preserved spontaneous breathing: a prospective, randomized, controlled clinical trial.
Topics: Alfentanil; Benzodiazepines; Bronchoscopy; Humans; Hypnotics and Sedatives; Hypotension; Propofol; P | 2023 |
Comparison of remimazolam and propofol induction on hemodynamic response in hypertensive patients.
Topics: Anesthesia, General; Hemodynamics; Humans; Hypertension; Hypotension; Propofol | 2023 |
The safety and efficacy of remimazolam tosylate combined with propofol in upper gastrointestinal endoscopy: A multicenter, randomized clinical trial.
Topics: Benzodiazepines; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Hypotension; Propofol | 2023 |
The preventive effect of 5-hydroxytryptamine-3 receptor antagonist on blood pressure reduction and postoperative nausea and vomiting during general anesthesia induction: A double-blinded, randomized controlled trial.
Topics: Anesthesia, General; Blood Pressure; Ephedrine; Humans; Hypotension; Pain, Postoperative; Phenylephr | 2023 |
Comparison of different ratios of propofol-ketamine admixture in rapid-sequence induction of anesthesia for emergency laparotomy: a randomized controlled trial.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Humans; Hypotension; Ketamine; Laparotomy; Nor | 2023 |
Norepinephrine prevents hypotension in older patients under spinal anesthesia with intravenous propofol sedation: a randomized controlled trial.
Topics: Aged; Anesthesia, Spinal; Double-Blind Method; Humans; Hypotension; Norepinephrine; Postoperative Co | 2023 |
Propofol for endotracheal intubation in neonates: a dose-finding trial.
Topics: Dose-Response Relationship, Drug; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotens | 2020 |
Efficacy of an Oxycodone-Propofol Combination versus a Fentanyl-Propofol Combination in Conscious Sedation during Therapeutic Endoscopic Retrograde Cholangiopancreatography in Elderly Patients.
Topics: Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Bradycardia; Cholangiopancreatography, E | 2021 |
Effect of remimazolam induction on hemodynamics in patients undergoing valve replacement surgery: A randomized, double-blind, controlled trial.
Topics: Adult; Aged; Anesthetics, Intravenous; Aortic Valve; Arterial Pressure; Benzodiazepines; Bradycardia | 2021 |
Thoracic Epidural Analgesia With Levobupivacaine Reduces Remifentanil and Propofol Consumption Evaluated by Closed-Loop Titration Guided by the Bispectral Index: A Double-Blind Placebo-Controlled Study.
Topics: Aged; Analgesia, Epidural; Anesthesia, Closed-Circuit; Anesthesia, Epidural; Anesthetics, Intravenou | 2017 |
Efficacy and safety of etomidate-based sedation compared with propofol-based sedation during ERCP in low-risk patients: a double-blind, randomized, noninferiority trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retro | 2018 |
Comparison of dexmedetomidine and fentanyl to prevent haemodynamic response to skull pin application in neurosurgery: double blind randomized controlled trial.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Bone Nails; Craniotomy; Dexmedetomidine; Double-Bli | 2017 |
Bispectral index to guide induction of anesthesia: a randomized controlled study.
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Consc | 2018 |
Use of propofol for prevention of post-delivery nausea during cesarean section: a double-blind, randomized, placebo-controlled trial.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Sect | 2018 |
A randomized controlled trial comparing methohexital and propofol for induction in patients receiving angiotensin axis blockade.
Topics: Aged; Anesthesia; Anesthetics, Intravenous; Angiotensin II; Angiotensin Receptor Antagonists; Angiot | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Comparison between hemodynamic effects of propofol and thiopental during general anesthesia induction with remifentanil infusion: a double-blind, age-stratified, randomized study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Double-Blind Method; | 2019 |
Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial.
Topics: Adult; Anesthetics, Intravenous; Critical Illness; Dose-Response Relationship, Drug; Drug Monitoring | 2019 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The potential regimen of target-controlled infusion of propofol in flexible bronchoscopy sedation: a randomized controlled trial.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopes; Conscious Sedation; Female; Humans; Hypotension; Hypo | 2013 |
The effect of nitrous oxide inhalation on the hypotensive response to propofol: a randomized controlled trial.
Topics: Administration, Inhalation; Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure | 2014 |
Preoperative oral rehydration solution intake volume does not affect relative change of mean arterial blood pressure and crystalloid redistribution during general anesthesia in low-risk patients: an observational cohort study.
Topics: Adult; Anesthesia, General; Blood Pressure; Cohort Studies; Female; Humans; Hypotension; Isotonic So | 2014 |
Clinical evaluation of propofol as sedative for endotracheal intubation in neonates.
Topics: Anesthetics, Intravenous; Humans; Hypotension; Infant, Newborn; Intensive Care, Neonatal; Intubation | 2013 |
Stepwise sedation for elderly patients with mild/moderate COPD during upper gastrointestinal endoscopy.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Blood Pressure; Chi-Square Distribution; China; Dr | 2013 |
Minimal and deep sedation during ablation of ventricular tachycardia.
Topics: Acidosis; Adult; Aged; Bradycardia; Catheter Ablation; Conscious Sedation; Deep Sedation; Feasibilit | 2014 |
Intrathecal fentanyl decreases the optimal effect site concentration of propofol during spinal anaesthesia.
Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Bupiv | 2014 |
Midazolam and propofol used alone or sequentially for long-term sedation in critically ill, mechanically ventilated patients: a prospective, randomized study.
Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthetics, Intravenous; Critical Illness; Dru | 2014 |
Blood pressure response to combined general anaesthesia/interscalene brachial plexus block for outpatient shoulder arthroscopy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Anesthesia, General; Ane | 2014 |
A randomized controlled trial of the effect of preoperative dexmedetomidine on the half maximal effective concentration of propofol for successful i-gel insertion without muscle relaxants.
Topics: Adult; Anesthesia, General; Bradycardia; Cough; Dexmedetomidine; Female; Heart Rate; Humans; Hypoten | 2015 |
Hemodynamic responses during induction: comparison of Marsh and Schnider pharmacokinetic models.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Body Mass Index; China; Dose-Response Relationship, Dru | 2015 |
A prospective, randomized controlled trial of conscious sedation using propofol combined with inhaled nitrous oxide for dental treatment.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Inh | 2015 |
Comparison of the hemodynamic response to induction and intubation during a target-controlled infusion of propofol with 2 different pharmacokinetic models. A prospective ramdomized trial.
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Consciousness Monitor | 2015 |
A presedation fluid bolus does not decrease the incidence of propofol-induced hypotension in pediatric patients.
Topics: Child, Preschool; Conscious Sedation; Drug Monitoring; Evoked Potentials, Auditory, Brain Stem; Fema | 2015 |
Propofol-ketamine combination: a choice with less complications and better hemodynamic stability compared to propofol? On a prospective study in a group of colonoscopy patients.
Topics: Anesthetics, Combined; Colonoscopy; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; H | 2016 |
A randomized, controlled trial to compare the efficacy and safety profile of a dexmedetomidine-ketamine combination with a propofol-fentanyl combination for ERCP.
Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recover | 2016 |
[Effects of dexmedetomidine on propofol dosage in target-controlled infusion and hemodynamics during laparoscopic surgery under general anesthesia].
Topics: Anesthesia, General; Blood Pressure; Bradycardia; Dexmedetomidine; Heart Rate; Hemodynamics; Humans; | 2015 |
Prewarming neurosurgical patients to minimize hypotension on induction of anesthesia: a randomized trial.
Topics: Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Body Temperature; Female; Heart Rate; Humans; | 2016 |
Etomidate plus propofol versus propofol alone for sedation during gastroscopy: a randomized prospective clinical trial.
Topics: Adult; Anesthetics, Intravenous; Attitude of Health Personnel; Bradycardia; Drug Therapy, Combinatio | 2016 |
Determination of the appropriate propofol infusion rate for outpatient upper gastrointestinal endoscopy-a randomized prospective study.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthetics, Intravenous; Conscio | 2016 |
Bispectral Index Monitoring Reduces the Dosage of Propofol and Adverse Events in Sedation for Endobronchial Ultrasound.
Topics: Aged; Anesthetics, Intravenous; Bronchoscopy; Consciousness Monitors; Deep Sedation; Endosonography; | 2016 |
Comparing the efficacy and safety between propofol and dexmedetomidine for sedation in claustrophobic adults undergoing magnetic resonance imaging (PADAM trial).
Topics: Adult; Aged; Anxiety; Bradycardia; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; | 2016 |
The effect of prophylactic phenylephrine on systemic hypotension during induction of anaesthesia with propofol in patients over 55 years old.
Topics: Aged; Anesthesia; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; | 2016 |
[Efficacy of spinal anesthesia with small-dose lidocaine in ambulatory prostate biopsy procedures for elderly patients : comparison with propofol anesthesia].
Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, General; Anesthesia, Spinal; Biopsy; Humans; Hypot | 2008 |
Controlled hypotension in adults undergoing choroidal melanoma resection: comparison between the efficacy of nitroprusside and magnesium sulphate.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Choroid Neoplasms; Female; Heart Rate; Hemodynamics | 2008 |
Prevention of hypotension during propofol induction: a comparison of preloading with 3.5% polymers of degraded gelatin (Haemaccel) and intravenous ephedrine.
Topics: Adult; Anesthesia; Anesthetics, Intravenous; Ephedrine; Female; Humans; Hypotension; Infusions, Intr | 2008 |
[Peribulbar anesthesia: efficacy of a single injection with a limited local anesthetic volume].
Topics: Aged; Amides; Anesthetics, Local; Cataract Extraction; Dose-Response Relationship, Drug; Drug Combin | 2008 |
Hypotensive anesthesia with esmolol. Assessment of hemodynamics, consumption of anesthetic drugs, and recovery.
Topics: Adolescent; Adult; Anesthetics; Hemodynamics; Humans; Hypotension; Middle Aged; Piperidines; Propano | 2009 |
Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia-induced hypotension.
Topics: Adult; Aged; Anesthesia, General; Ephedrine; Female; Fentanyl; Frontal Lobe; Hemodynamics; Humans; H | 2010 |
Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia-induced hypotension.
Topics: Adult; Aged; Anesthesia, General; Ephedrine; Female; Fentanyl; Frontal Lobe; Hemodynamics; Humans; H | 2010 |
Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia-induced hypotension.
Topics: Adult; Aged; Anesthesia, General; Ephedrine; Female; Fentanyl; Frontal Lobe; Hemodynamics; Humans; H | 2010 |
Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia-induced hypotension.
Topics: Adult; Aged; Anesthesia, General; Ephedrine; Female; Fentanyl; Frontal Lobe; Hemodynamics; Humans; H | 2010 |
Can intravenous atropine prevent bradycardia and hypotension during induction of total intravenous anesthesia with propofol and remifentanil?
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Atropine; Bradycardia; Female; Human | 2010 |
Dose-dependent hemodynamic effects of propofol induction following brotizolam premedication in hypertensive patients taking angiotensin-converting enzyme inhibitors.
Topics: Adult; Aged; Anesthetics, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Azepines; Blood Pre | 2010 |
Effect of auditory evoked potential-guided anaesthesia on consumption of anaesthetics and early postoperative cognitive dysfunction: a randomised controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Anesthesia, General; Anesthetics, General; C | 2011 |
Sedation during upper GI endoscopy in cirrhotic outpatients: a randomized, controlled trial comparing propofol and fentanyl with midazolam and fentanyl.
Topics: Analgesics, Opioid; Anesthesia Recovery Period; Bradycardia; Conscious Sedation; Deep Sedation; Endo | 2011 |
Hydration status after overnight fasting as measured by urine osmolality does not alter the magnitude of hypotension during general anesthesia in low risk patients.
Topics: Adult; Anesthesia, General; Blood Pressure; Crystallization; Electric Impedance; Female; Fentanyl; H | 2011 |
Dose requirement and complications of diluted and undiluted propofol for deep sedation in endoscopic retrograde cholangiopancreatography.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Cholangiopancreatography, Endosco | 2011 |
Feasibility and safety of propofol sedation in flexible bronchoscopy.
Topics: Adult; Aged; Bronchoscopy; Conscious Sedation; Feasibility Studies; Humans; Hypnotics and Sedatives; | 2011 |
Moderate sedation for elective upper endoscopy with balanced propofol versus fentanyl and midazolam alone: a randomized clinical trial.
Topics: Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Deep Sedation; Endoscopy, Digesti | 2012 |
Bispectral index monitoring of midazolam and propofol sedation during endoscopic retrograde cholangiopancreatography: a randomized clinical trial (the EndoBIS study).
Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Bradycardia; Cholangiopancreatography, Endoscop | 2012 |
Intermittent manually controlled versus continuous infusion of propofol for deep sedation during interventional endoscopy: a prospective randomized trial.
Topics: Anesthesia Recovery Period; Cholangiopancreatography, Endoscopic Retrograde; Deep Sedation; Endosono | 2012 |
Propofol sedation with bispectral index monitoring is useful for endoscopic submucosal dissection: a randomized prospective phase II clinical trial.
Topics: Adenoma; Aged; Aged, 80 and over; Anesthetics, Intravenous; Bradycardia; Chi-Square Distribution; Co | 2012 |
A comparison of 3 anesthetic protocols for 24 hours of mechanical ventilation in cats.
Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Cats; Cross- | 2012 |
Comparison of effects of ephedrine, lidocaine and ketamine with placebo on injection pain, hypotension and bradycardia due to propofol injection: a randomized placebo controlled clinical trial.
Topics: Adult; Anesthetics, Intravenous; Bradycardia; Double-Blind Method; Ephedrine; Female; Humans; Hypote | 2012 |
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P | 2013 |
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P | 2013 |
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P | 2013 |
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P | 2013 |
Low effect-site concentration of propofol target-controlled infusion reduces the risk of hypotension during endoscopy in a Taiwanese population.
Topics: Adult; Aged; Anesthetics, Intravenous; Conscious Sedation; Dose-Response Relationship, Drug; Drug Ad | 2013 |
Spinal block or total intravenous anaesthesia with propofol and remifentanil for gynaecological outpatient procedures.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Spinal; Anesthetics, Combined; Anesthetics, | 2002 |
[Effect of propofol and propofol combined with ketamine on cardiovascular system].
Topics: Adolescent; Adult; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Blood | 2000 |
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial.
Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se | 2002 |
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial.
Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se | 2002 |
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial.
Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se | 2002 |
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial.
Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se | 2002 |
Propofol for procedural sedation in children in the emergency department.
Topics: Adjuvants, Anesthesia; Adolescent; Analgesics, Opioid; Anesthetics, Combined; Bradycardia; Child; Ch | 2003 |
Propofol sedation by emergency physicians for elective pediatric outpatient procedures.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Ambulatory Care; Bradycardia; Child; Child, Preschool; Cli | 2003 |
Cost-effectiveness and high patient satisfaction in the elderly: sevoflurane versus propofol anaesthesia.
Topics: Aged; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intrav | 2004 |
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti | 2003 |
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti | 2003 |
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti | 2003 |
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti | 2003 |
Effect of preoperative discontinuation of antipsychotics in schizophrenic patients on outcome during and after anaesthesia.
Topics: Adult; Analysis of Variance; Anesthesia; Anesthesia Recovery Period; Anesthetics, Intravenous; Antip | 2004 |
Hydroxyethylstarch 6% preload does not prevent the hypotension following induction with propofol and fentanyl.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Electrocardiography; Female; Fentanyl; Heart Rate; | 2004 |
A prospective, randomized, double-blind comparison of unilateral spinal anesthesia with hyperbaric bupivacaine, ropivacaine, or levobupivacaine for inguinal herniorrhaphy.
Topics: Aged; Air Pressure; Amides; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Digestive System Su | 2004 |
Induced hypotension for tympanoplasty: a comparison of desflurane, isoflurane and sevoflurane.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, | 2004 |
Propofol for deep procedural sedation in the ED.
Topics: Adolescent; Adult; Analgesics, Opioid; Apnea; Conscious Sedation; Dose-Response Relationship, Drug; | 2005 |
Comparison of ephedrine and ketamine in prevention of injection pain and hypotension due to propofol induction.
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Double-Blind Met | 2005 |
Effect of hypercapnia on arterial hypotension after induction of anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno | 2005 |
Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study.
Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Comorbidity; Conscious Sedation; Feasibility | 2005 |
Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study.
Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Comorbidity; Conscious Sedation; Feasibility | 2005 |
Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study.
Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Comorbidity; Conscious Sedation; Feasibility | 2005 |
Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study.
Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Comorbidity; Conscious Sedation; Feasibility | 2005 |
A comparison of spinal anesthesia with small-dose lidocaine and general anesthesia with fentanyl and propofol for ambulatory prostate biopsy procedures in elderly patients.
Topics: Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia Recovery P | 2007 |
Preoperative ultra short-term entropy predicts arterial blood pressure fluctuation during the induction of anesthesia.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Electrocardiography; Entropy; | 2007 |
Propofol causes more hypotension than etomidate in patients with severe aortic stenosis: a double-blind, randomized study comparing propofol and etomidate.
Topics: Aged; Analysis of Variance; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2007 |
Autonomic cardiac control with xenon anaesthesia in patients at cardiovascular risk.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Autonomic Nervous System; Blood Pressure; E | 2007 |
The effect of ephedrine on intubating conditions and haemodynamics during rapid tracheal intubation using propofol and rocuronium.
Topics: Adolescent; Adult; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Dose | 2007 |
Attenuation of hypotension using phenylephrine during induction of anaesthesia with propofol.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Cardiotonic Agents; Female; Humans; Hypotension; | 2007 |
Prevention of propofol-induced injection pain by sufentanil: a placebo-controlled comparison with remifentanil.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Double-Blind | 2008 |
Hypotensive anesthesia with propofol and remifentanil: protective effect of alpha-tocopherol on renal function.
Topics: Acetylglucosaminidase; Adult; alpha-Tocopherol; Anesthesia, Intravenous; Anesthetics, Intravenous; A | 2008 |
A comparison of propofol and isoflurane anaesthesia: the need for ephedrine and glycopyrrolate.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Anesthesia, Inhalation; Anesthesia, Intraven | 1995 |
Modulating effects of lignocaine on propofol.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Anesthesia, Intravenous; Female; Forearm; Hand; Hu | 1995 |
Hemodynamic effects of propofol: data from over 25,000 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Bradycardia; Female; Humans; Hy | 1993 |
Hemodynamic effects of propofol: data from over 25,000 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Bradycardia; Female; Humans; Hy | 1993 |
Hemodynamic effects of propofol: data from over 25,000 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Bradycardia; Female; Humans; Hy | 1993 |
Hemodynamic effects of propofol: data from over 25,000 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Bradycardia; Female; Humans; Hy | 1993 |
A comparison of propofol with methohexital and isoflurane in two general anesthetic techniques.
Topics: Adolescent; Adult; Alfentanil; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, General; | 1993 |
The haemodynamic effects of propofol in combination with ephedrine.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Dose-Response Relationship, Drug; Ephedrine; Female | 1996 |
Prophylaxis against the systemic hypotension induced by propofol during rapid-sequence intubation.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Ephedrine; Female; Humans; Hypotension; Intubation, | 1995 |
Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery.
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Coronary Artery Bypass; Enflura | 1997 |
The arterial blood propofol concentration preventing movement in 50% of healthy women after skin incision.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Biopsy; Blood Pressure; Breast; Dermatolog | 1997 |
Prophylactic ephedrine attenuates the hemodynamic response to propofol in elderly female patients.
Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Ephedrine; Female; Fentanyl; Heart Rate; Humans; Hyp | 1998 |
Treatment of refractory status epilepticus with propofol: clinical and pharmacokinetic findings.
Topics: Adult; Aged; Barbiturates; Clinical Protocols; Drug Administration Schedule; Drug Therapy, Combinati | 1998 |
Administration of a crystalloid fluid preload does not prevent the decrease in arterial blood pressure after induction of anaesthesia with propofol and fentanyl.
Topics: Adult; Anesthetics, Intravenous; Crystalloid Solutions; Female; Fentanyl; Fluid Therapy; Heart Rate; | 1998 |
Haemodynamic effects of induction of general anaesthesia with propofol during epidural anaesthesia.
Topics: Analysis of Variance; Anesthesia, Epidural; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood | 1998 |
Effects of nicardipine-, nitroglycerin-, and prostaglandin E1-induced hypotension on human cerebrovascular carbon dioxide reactivity during propofol-fentanyl anesthesia.
Topics: Adult; Alprostadil; Analysis of Variance; Anesthetics, Intravenous; Antihypertensive Agents; Blood F | 1999 |
Ephedrine, dopamine, or dobutamine to treat hypotension with propofol during epidural anesthesia.
Topics: Adrenergic Agents; Analysis of Variance; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics | 2000 |
The effect of prophylactic metaraminol on systemic hypotension caused by induction of anaesthesia with propofol in patients over 55 years old.
Topics: Adrenergic alpha-Agonists; Aged; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Doub | 2001 |
Influence of hypotensive and normotensive anesthesia on platelet aggregability and hemostatic markers in orthognathic surgery.
Topics: Adult; Anesthesia; Anesthetics, Intravenous; Biomarkers; Blood Loss, Surgical; Female; Hemostasis; H | 2001 |
Terlipressin-ephedrine versus ephedrine to treat hypotension at the induction of anesthesia in patients chronically treated with angiotensin converting-enzyme inhibitors: a prospective, randomized, double-blinded, crossover study.
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Angiotensin-Converting Enzyme Inhibitors; B | 2002 |
Venodilation contributes to propofol-mediated hypotension in humans.
Topics: Adult; Aged; Anesthesia; Blood Pressure; Carbon Dioxide; Cardiac Output; Electroencephalography; For | 1992 |
The effect of pre-induction glycopyrronium on the haemodynamic response of elderly patients to anaesthesia with propofol.
Topics: Aged; Aged, 80 and over; Anesthesia, Intravenous; Blood Pressure; Double-Blind Method; Female; Glyco | 1992 |
141 other studies available for propofol and Hypotension
Article | Year |
---|---|
Hemodynamic Effects of Ketamine Compared With Propofol or Dexmedetomidine as Continuous ICU Sedation.
Topics: Adult; Bradycardia; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Hypotension; Int | 2022 |
Gene-gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol.
Topics: Adult; Aged; Anesthetics, Intravenous; Cross-Sectional Studies; Female; Genotype; Haplotypes; Humans | 2022 |
Comparison of effectiveness, cost and safety between moderate sedation and deep sedation under esophagogastroduodenoscopy in Chinese population: a quasi-experimental study.
Topics: Aged; Conscious Sedation; Cost-Benefit Analysis; Deep Sedation; Endoscopy, Digestive System; Humans; | 2022 |
Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65.
Topics: Aged; Anesthetics, Intravenous; Humans; Hypotension; Propofol; Retrospective Studies; Surgical Wound | 2022 |
Isoelectric Electroencephalography in Infants and Toddlers during Anesthesia for Surgery: An International Observational Study.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Elect | 2022 |
Isoelectric Electroencephalography in Infants and Toddlers during Anesthesia for Surgery: An International Observational Study.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Elect | 2022 |
Isoelectric Electroencephalography in Infants and Toddlers during Anesthesia for Surgery: An International Observational Study.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Elect | 2022 |
Isoelectric Electroencephalography in Infants and Toddlers during Anesthesia for Surgery: An International Observational Study.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Elect | 2022 |
Effects of intravenous acepromazine and butorphanol on propofol dosage for induction of anesthesia in healthy Beagle dogs.
Topics: Acepromazine; Anesthesia; Animals; Apnea; Butorphanol; Dog Diseases; Dogs; Female; Hypotension; Male | 2022 |
Comment on: "Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65".
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Humans; Hypotension; Propofol | 2022 |
Comparison of Standard-Dose Versus High-Dose Dexmedetomidine in Extracorporeal Membrane Oxygenation.
Topics: Adult; Analgesics; Bradycardia; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Humans; Hypnot | 2023 |
Response to comment on: "Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65".
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Humans; Hypotension; Propofol | 2022 |
Blockade of endothelial Mas receptor restores the vasomotor response to phenylephrine in human resistance arterioles pretreated with captopril and exposed to propofol.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arterioles; Captopril; Humans; Hypotension | 2022 |
Low-dose adjuvant dexmedetomidine did not decrease propofol sedation requirements in children undergoing gastrointestinal endoscopy.
Topics: Anesthesia; Child; Cohort Studies; Dexmedetomidine; Endoscopy, Gastrointestinal; Humans; Hypnotics a | 2022 |
Target-controlled infusion during MitraClip procedures in deep-sedation with spontaneous breathing.
Topics: Anesthesia, General; Drug-Related Side Effects and Adverse Reactions; Humans; Hypotension; Propofol; | 2022 |
Target-controlled infusion during MitraClip procedures in deep-sedation with spontaneous breathing.
Topics: Anesthesia, General; Drug-Related Side Effects and Adverse Reactions; Humans; Hypotension; Propofol; | 2022 |
Target-controlled infusion during MitraClip procedures in deep-sedation with spontaneous breathing.
Topics: Anesthesia, General; Drug-Related Side Effects and Adverse Reactions; Humans; Hypotension; Propofol; | 2022 |
Target-controlled infusion during MitraClip procedures in deep-sedation with spontaneous breathing.
Topics: Anesthesia, General; Drug-Related Side Effects and Adverse Reactions; Humans; Hypotension; Propofol; | 2022 |
A 67-Year-Old Woman With Fluctuating Hypertension and Hypotension After Elective Surgery.
Topics: Aged; Dexmedetomidine; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Hypotension; Neuromu | 2023 |
5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats.
Topics: Aminolevulinic Acid; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Bupivacaine; Hype | 2023 |
Effects of smoking on controlled hypotension with nitroglycerin during ear-nose-throat surgery.
Topics: Anesthesia, General; Humans; Hypotension; Hypotension, Controlled; Nicotine; Nitroglycerin; Pharynx; | 2023 |
The risks of sedation and pain control during burn resuscitation: Increased opioids lead to over-resuscitation and hypotension.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Burns; Dexmedetomidine; Fluid Therapy; Humans; Hypnotics | 2023 |
Use of Propofol Plus Dexmedetomidine in Patients Experiencing Severe Alcohol Withdrawal in the Intensive Care Unit.
Topics: Alcoholism; Bradycardia; Critical Care; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; | 2020 |
Comparison of drugs used for intubation of pediatric trauma patients.
Topics: Adolescent; Brain Injuries, Traumatic; Child; Child, Preschool; Etomidate; Female; Hospitals, Pediat | 2020 |
Propofol sedation with a target-controlled infusion pump in elderly patients undergoing ERCP.
Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Humans; Hypnotics and Sed | 2020 |
DEXmedetomidine compared to PROpofol in NEurocritical Care [DEXPRONE]: A multicenter retrospective evaluation of clinical utility and safety.
Topics: Adult; Aged; Bradycardia; Critical Care; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotic | 2020 |
Deep sedation using propofol target-controlled infusion for gastrointestinal endoscopic procedures: a retrospective cohort study.
Topics: Aged; Anesthetics, Intravenous; Cohort Studies; Deep Sedation; Drug Delivery Systems; Endoscopy, Gas | 2020 |
Pre-treatment with the angiotensin receptor 1 blocker losartan protects renal blood flow and oxygen delivery after propofol-induced hypotension in pigs.
Topics: Anesthetics, Intravenous; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; Hypoten | 2020 |
Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability.
Topics: Adult; Aged; Anesthetics, Intravenous; Arginase; Female; Genotype; Haplotypes; Humans; Hypotension; | 2021 |
Mechanisms contributing to hypotension after anesthetic induction with sufentanil, propofol, and rocuronium: a prospective observational study.
Topics: Anesthetics; Anesthetics, Intravenous; Blood Pressure; Hemodynamics; Humans; Hypotension; Propofol; | 2022 |
Causes of arterial hypotension during anesthetic induction with propofol investigated with perfusion index and ClearSightTM in young and elderly patients.
Topics: Aged; Anesthetics; Anesthetics, Intravenous; Blood Pressure; Humans; Hypotension; Perfusion Index; P | 2021 |
Predicting hypotension during anesthesia: Variation in pulse oximetry plethysmography predicts propofol-induced hypotension in children.
Topics: Anesthesia; Blood Pressure; Child; Humans; Hypotension; Hypotension, Controlled; Oximetry; Plethysmo | 2021 |
Deceleration capacity of heart rate variability as a predictor of sedation related hypotension.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Electrocardiography; Female; H | 2021 |
Propofol-induced uric acid crystals: A case of cloudy urine.
Topics: Adolescent; Anesthetics, Intravenous; Bradycardia; Child; Humans; Hypotension; Male; Propofol; Uric | 2021 |
Bradyarrhythmia and hypotension during anesthetic induction-reconsideration of nifedipine: a case report.
Topics: Anesthetics; Bradycardia; Humans; Hypotension; Nifedipine; Propofol | 2021 |
The First US Clinical Experience With Computer-Assisted Propofol Sedation: A Retrospective Observational Comparative Study on Efficacy, Safety, Efficiency, and Endoscopist and Patient Satisfaction.
Topics: Aged; Anesthesiologists; Conscious Sedation; Drug Therapy, Computer-Assisted; Endoscopy; Female; Hum | 2017 |
An Analysis of Substandard Propofol Detected in Use in Zambian Anesthesia.
Topics: Anesthesia; Anesthesiology; Anesthetics, Intravenous; Bronchial Spasm; Drug Contamination; Gas Chrom | 2017 |
A Simulation Study of Propofol Effect-Site Concentration for Appropriate Sedation in Pediatric Patients Undergoing Brain MRI: Pharmacodynamic Analysis.
Topics: Adolescent; Anesthesia; Anesthetics, Intravenous; Bradycardia; Brain; Child; Dose-Response Relations | 2017 |
Angiotensin converting enzyme inhibitors enhance the hypotensive effects of propofol by increasing nitric oxide production.
Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin Receptor Antagonists; Angiotensin-Converting En | 2018 |
A Comparison of Safety and Efficacy of Dexmedetomidine and Propofol in Children with Autism and Autism Spectrum Disorders Undergoing Magnetic Resonance Imaging.
Topics: Anesthesia, Intravenous; Autism Spectrum Disorder; Child; Child, Preschool; Dexmedetomidine; Female; | 2018 |
Procedural sedation by advanced care paramedics for emergency gastrointestinal endoscopy.
Topics: Allied Health Personnel; Analgesics; Arrhythmias, Cardiac; Datasets as Topic; Emergency Service, Hos | 2019 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood | 2018 |
[Hemodynamic effects of cafedrine/theodrenaline on anesthesia-induced hypotension].
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Drug Combinations; Femal | 2018 |
Effects From Continuous Infusions of Dexmedetomidine and Propofol on Hemodynamic Stability in Critically Ill Adult Patients With Septic Shock.
Topics: Adult; Aged; Bradycardia; Critical Care; Critical Care Outcomes; Critical Illness; Dexmedetomidine; | 2020 |
Hemodynamic Effects of Propofol for Induction of Rapid Sequence Intubation in Traumatically Injured Patients.
Topics: Adult; Emergency Service, Hospital; Female; Hemodynamics; Hospital Mortality; Humans; Hypnotics and | 2018 |
The Effects of Intravenous Lipid Emulsion Therapy in the Prevention of Depressive Effects of Propofol on Cardiovascular and Respiratory Systems: An Experimental Animal Study.
Topics: Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Fat Emulsions, Intravenous; Heart Ra | 2018 |
Propofol sedation without endotracheal intubation is safe for endoscopic submucosal dissection in the esophagus and stomach.
Topics: Aged; Analgesics, Opioid; Anesthetics, Intravenous; Cough; Endoscopic Mucosal Resection; Esophageal | 2019 |
Deep sedation for transvenous lead extraction: a large single-centre experience.
Topics: Cardiac Catheters; Cardiac Imaging Techniques; Deep Sedation; Defibrillators, Implantable; Device Re | 2019 |
Computer-Assisted Propofol Sedation for Esophagogastroduodenoscopy Is Effective, Efficient, and Safe.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Anesthetists; Blood Gas Monitorin | 2019 |
Behavior of a dual closed-loop controller of propofol and remifentanil guided by the bispectral index for postoperative sedation of adult cardiac surgery patients: a preliminary open study.
Topics: Adult; Aged; Airway Extubation; Anesthesia, Closed-Circuit; Cardiac Surgical Procedures; Critical Ca | 2020 |
Case report: profound hypotension after anesthetic induction with propofol in patients treated with rifampin.
Topics: Adult; Aged; Anesthesia, Intravenous; Antibiotics, Antitubercular; Case-Control Studies; Drug Intera | 2013 |
Incidence of intraoperative hypotension during isoflurane-fentanyl and propofol-fentanyl anaesthesia in dogs.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dog Diseases; Dogs; | 2013 |
Increase in prominence of electrocardiographic J waves after a single dose of propofol in a patient with early ventricular repolarisation.
Topics: Aged, 80 and over; Anesthetics, Intravenous; Electrocardiography; Female; Humans; Hypotension; Intra | 2014 |
Safety and efficacy of propofol administered by paediatricians during procedural sedation in children.
Topics: Child; Child, Preschool; Contraindications; Deep Sedation; Female; Humans; Hypotension; Infant; Lary | 2014 |
Can a validated sleep apnea scoring system predict cardiopulmonary events using propofol sedation for routine EGD or colonoscopy? A prospective cohort study.
Topics: Adult; Age Factors; Aged; Body Mass Index; Colonoscopy; Female; Humans; Hypnotics and Sedatives; Hyp | 2014 |
Predictors of severe hypotension in neurocritical care patients sedated with propofol.
Topics: Aged; Antihypertensive Agents; Arterial Pressure; Cohort Studies; Critical Care; Drug Administration | 2014 |
Same-day bidirectional endoscopy with nonanesthesiologist administration of propofol: safety and cost-effectiveness compared with separated exams.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bradycardia; Colonoscopy; Conscious Sedation; Cost-Benef | 2014 |
Management and complications of anaesthesia during balloon valvuloplasty for pulmonic stenosis in dogs: 39 cases (2000 to 2012).
Topics: Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Arrhythmias, Card | 2014 |
A comparison of severe hemodynamic disturbances between dexmedetomidine and propofol for sedation in neurocritical care patients.
Topics: Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Bradycardia; Critical Care; De | 2014 |
Anesthetic management and outcomes for patients with pulmonary hypertension and intracardiac shunts and Eisenmenger syndrome: a review of institutional experience.
Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics; Eisenmenger Complex; Etomidate; Hospitals, Univers | 2014 |
[Retrospective evaluation of predictors and frequency of hypotension in hypertensive patients after induction of general anesthesia].
Topics: Age Factors; Aged; Anesthesia, General; Blood Pressure; Forecasting; Humans; Hypertension; Hypotensi | 2014 |
[Incorrect programming of a target controlled infusion pump. Case SENSAR of the trimester].
Topics: Anesthetics, General; Aortic Valve; Drug Overdose; Equipment Failure; Equipment Failure Analysis; He | 2014 |
Cardiovascular Collapse After Induction.
Topics: Adrenergic alpha-Agonists; Aged, 80 and over; Anaphylaxis; Anesthetics, Intravenous; Anti-Allergic A | 2015 |
[Ventricular fibrillation and cardiorespiratory arrest during dexmedetomidine administration].
Topics: Adrenergic alpha-2 Receptor Agonists; Advanced Cardiac Life Support; Aged; Airway Extubation; Aortic | 2015 |
Methodology of motor evoked potentials in a rabbit model.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apnea; Disease Models, Animal; Evoked Po | 2015 |
Propofol sedation with a target-controlled infusion pump and bispectral index monitoring system in elderly patients during a complex upper endoscopy procedure.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Deep Sedation; Dissection; Drug Monitor | 2016 |
Extracorporeal membrane oxygenation and sustained low-efficiency diafiltration successfully resuscitated propofol infusion syndrome during refractory status epilepticus.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Extracorporeal Membrane Oxygenation; Humans | 2015 |
Age correlates with hypotension during propofol-based anesthesia for endoscopic retrograde cholangiopancreatography.
Topics: Adult; Aged; Anesthesia; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Humans | 2015 |
[Abnormal Low Blood Pressure after Induction of General Anesthesia in a Patient on Medication for Depression].
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local | 2015 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Sedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
Topics: Birth Weight; Bradycardia; Female; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; In | 2016 |
Deep Sedation for Pediatric Dental Procedures: Is this a Safe and Effective Option?
Topics: Adjuvants, Anesthesia; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Intravenous; Cat | 2016 |
Safety and clinical effectiveness of propofol for endoscopic retrograde cholangiopancreatography.
Topics: Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Choledocholi | 2016 |
Ultrasound measurement of inferior vena cava collapse predicts propofol-induced hypotension.
Topics: Aged; Anesthetics, Intravenous; Female; Humans; Hypotension; Male; Middle Aged; Predictive Value of | 2016 |
Propofol sedation administered by cardiologists for patients undergoing catheter ablation for ventricular tachycardia.
Topics: Aged; Blood Pressure; Cardiologists; Catheter Ablation; Defibrillators, Implantable; Female; Germany | 2016 |
Safety of Target-Controlled Propofol Infusion by Gastroenterologists in Patients Undergoing Endoscopic Resection.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Anesthetics, Intravenous; Case-Control Studies; Deep Sed | 2016 |
Effects of propofol on vasopressor use in patients with sepsis and severe sepsis: A pilot study.
Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Female; Hospital Mortality; Humans; Hypnotics and Se | 2016 |
Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice.
Topics: Adult; Aged; Aged, 80 and over; Aging; Algorithms; Anesthesia, Intravenous; Anesthetics, Intravenous | 2016 |
A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients?
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; | 2016 |
Ultrasound Measurement Of Inferior Vena Cava Collapse Predicts Propofol Induced Hypotension.
Topics: Humans; Hypotension; Hypotension, Controlled; Propofol; Shock; Vena Cava, Inferior | 2017 |
Flexible bronchoscopy with moderate sedation in COPD: a case-control study.
Topics: Adult; Aged; Anesthetics, Intravenous; Bronchoscopy; Case-Control Studies; Conscious Sedation; Femal | 2017 |
Atypical presentation to rocuronium allergy in a 19-year-old female patient.
Topics: Adult; Anaphylaxis; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Cardiopulmonary Res | 2017 |
Low pre-operative heart rate variability and complexity are associated with hypotension after anesthesia induction in major abdominal surgery.
Topics: Abdomen; Aged; Algorithms; Anesthesia; Anesthesia, General; Autonomic Nervous System; Cohort Studies | 2018 |
Low pre-operative heart rate variability and complexity are associated with hypotension after anesthesia induction in major abdominal surgery.
Topics: Abdomen; Aged; Algorithms; Anesthesia; Anesthesia, General; Autonomic Nervous System; Cohort Studies | 2018 |
Low pre-operative heart rate variability and complexity are associated with hypotension after anesthesia induction in major abdominal surgery.
Topics: Abdomen; Aged; Algorithms; Anesthesia; Anesthesia, General; Autonomic Nervous System; Cohort Studies | 2018 |
Low pre-operative heart rate variability and complexity are associated with hypotension after anesthesia induction in major abdominal surgery.
Topics: Abdomen; Aged; Algorithms; Anesthesia; Anesthesia, General; Autonomic Nervous System; Cohort Studies | 2018 |
Bradycardia, hypotension and bronchospasm following remifentanil-propofol in a myathenic paitent treated by pyridostigmine--a case report.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Bradycardia; Bronchial Spasm; Cholinesterase I | 2008 |
Predictors of hemodynamic compromise with propofol during defibrillator implantation: a single center experience.
Topics: Aged; Conscious Sedation; Defibrillators, Implantable; Female; Humans; Hypotension; Incidence; Male; | 2009 |
Frontal lobe oxygenation is maintained during hypotension following propofol-fentanyl anesthesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthetics, Intravenous; Cerebrov | 2009 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
Pleth variability index predicts hypotension during anesthesia induction.
Topics: Algorithms; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; | 2010 |
The intravenous anesthetic propofol inhibits human L-type calcium channels by enhancing voltage-dependent inactivation.
Topics: Anesthetics, Intravenous; Atrial Appendage; Bradycardia; Calcium Channel Blockers; Calcium Channels, | 2011 |
A comparison of anesthetic complications between diabetic and nondiabetic dogs undergoing phacoemulsification cataract surgery: a retrospective study.
Topics: Acepromazine; Anesthesia, Intravenous; Animals; Bradycardia; Cataract; Diabetes Mellitus; Dog Diseas | 2010 |
Propofol as an induction agent for endotracheal intubation can cause significant arterial hypotension in preterm neonates.
Topics: Anesthetics, Intravenous; Blood Pressure; Humans; Hypotension; Infant; Infant, Newborn; Infant, Prem | 2010 |
High BMI in children as a risk factor for intraoperative hypotension.
Topics: Adolescent; Age Factors; Anesthesia, General; Anesthetics, Intravenous; Body Mass Index; Child; Chil | 2010 |
Severe cerebral desaturation during shoulder arthroscopy in the beach-chair position.
Topics: Anesthesia, General; Arthroscopy; Blood Gas Monitoring, Transcutaneous; Brain Ischemia; Cerebrovascu | 2010 |
The influence of duration of fluid abstinence on hypotension during propofol induction.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Consciousness Monitors; Dose-Resp | 2010 |
Evaluation of dexmedetomidine versus propofol-based sedation therapy in mechanically ventilated cardiac surgery patients at a tertiary academic medical center.
Topics: Aged; Aged, 80 and over; Cardiac Surgical Procedures; Clinical Protocols; Dexmedetomidine; Female; H | 2010 |
Safety of continuous propofol sedation for endoscopic procedures in elderly patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bradycardia; Colonoscopy; Conscious Sedation; Electroenc | 2011 |
Propofol infusion syndrome--a critical incident report highlighting the danger of reexposure.
Topics: Adult; Arrhythmias, Cardiac; Head Injuries, Closed; Humans; Hypnotics and Sedatives; Hypotension; In | 2011 |
Case scenario: bronchospasm during anesthetic induction.
Topics: Adult; Albuterol; Anesthesia; Anesthetics, Intravenous; Anti-Inflammatory Agents; Bronchial Spasm; B | 2011 |
Evaluation of dexmedetomidine: safety and clinical outcomes in critically ill trauma patients.
Topics: Adult; Analgesics; Antipsychotic Agents; Chi-Square Distribution; Critical Illness; Dexmedetomidine; | 2011 |
Propofol as an induction agent for endotracheal intubation can cause significant arterial hypotension in preterm infants.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Gestational Age; Humans; Hypotens | 2011 |
Adverse events during monitored anesthesia care for GI endoscopy: an 8-year experience.
Topics: Adolescent; Age Factors; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Body Mass Index; Bradyca | 2011 |
Nurse-administered propofol sedation for endoscopy: a risk analysis during an implementation phase.
Topics: Adult; Aged; Cholangiopancreatography, Endoscopic Retrograde; Clinical Competence; Deep Sedation; Ed | 2011 |
A retrospective analysis of proceduralist-directed, nurse-administered propofol sedation for implantable cardioverter-defibrillator procedures.
Topics: Aged; Anesthetics, Intravenous; Cardiac Pacing, Artificial; Conscious Sedation; Defibrillators, Impl | 2012 |
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St | 2012 |
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St | 2012 |
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St | 2012 |
Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation.
Topics: Aged; Anesthetics, Intravenous; Atrial Fibrillation; Cardiac Tamponade; Catheter Ablation; Cohort St | 2012 |
Nurse-administered propofol sedation for gastrointestinal endoscopic procedures: first Nordic results from implementation of a structured training program.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Clinical Competence; Deep Sedation; Educ | 2011 |
Obesity as a risk factor for sedation-related complications during propofol-mediated sedation for advanced endoscopic procedures.
Topics: Aged; Anesthetics, Intravenous; Body Mass Index; Conscious Sedation; Digestive System Diseases; Endo | 2011 |
Opioid receptor blockade prevents propofol-induced hypotension in rats.
Topics: Anesthetics, Intravenous; Animals; Blood Pressure; Hypotension; Naloxone; Narcotic Antagonists; Prop | 2012 |
Effects of propofol with hyperthermia in a rat model of endotoxemic shock.
Topics: Acidosis; Animals; Carbon Dioxide; Combined Modality Therapy; Cytokines; Drug Evaluation, Preclinica | 2012 |
Induction dose of propofol for pediatric patients undergoing procedural sedation in the emergency department.
Topics: Adolescent; Anesthetics, Intravenous; Child; Child, Preschool; Conscious Sedation; Dose-Response Rel | 2012 |
Haemodynamics and cerebral oxygenation during arthroscopic shoulder surgery in beach chair position under general anaesthesia.
Topics: Aged; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; | 2012 |
Endoscopist-administered propofol sedation is safe - a prospective evaluation of 10,000 patients in an outpatient practice.
Topics: Ambulatory Care; Bradycardia; Colonoscopy; Endoscopy, Gastrointestinal; Female; Humans; Hypnotics an | 2012 |
Perioperative plasma concentrations of atrial and brain natriuretic peptides in patients undergoing hip arthroplasty.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Combined; Arthr | 2002 |
General anesthesia or sedation in the intensive care unit: are we aware of the difference when we use propofol?
Topics: Anesthesia, General; Anesthetics, Intravenous; Apnea; Child; Conscious Sedation; Critical Care; Drug | 2003 |
The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aspartic Acid; Blood Gas Analysis; Blood | 2003 |
[Severe hypotension after induction of general anesthesia in a patient receiving an angiotensin II receptor antagonist and an alpha-blocker].
Topics: Adrenergic alpha-Antagonists; Anesthesia, General; Angiotensin II Type 1 Receptor Blockers; Antihype | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Predictors of hypotension after induction of general anesthesia.
Topics: Adult; Aged; Aging; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pr | 2005 |
Improved haemodynamics with sevoflurane in laminectomy in a child with Rubinstein-Taybi syndrome.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Humans; Hypotension; Intraoperative Compli | 2005 |
Propofol for emergency department procedural sedation and analgesia: a tale of three centers.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Antiemetics; Child; Child, Preschool; Conscio | 2006 |
[Anesthetic management with propofol for pheochromocytoma resection under monitoring of bispectral index and blood volume].
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Volume Dete | 2006 |
Recommendations for postinduction hypotension: are they supported by the evidence?
Topics: Anesthesia, Intravenous; Blood Pressure; Health Planning Guidelines; Humans; Hypotension; Hypovolemi | 2006 |
Hemodynamics with propofol: is propofol dangerous in classes III-V patients?
Topics: Anesthetics, Intravenous; Hemodynamics; Humans; Hypotension; Propofol | 2006 |
Propofol by infusion protocol for ED procedural sedation.
Topics: Adolescent; Adult; Aged; Clinical Protocols; Conscious Sedation; Delusions; Dose-Response Relationsh | 2006 |
Procedural sedation and analgesia in a Canadian adult tertiary care emergency department: a case series.
Topics: Age Distribution; Aged; Canada; Conscious Sedation; Drug Therapy, Combination; Drug Utilization; Eme | 2006 |
Emergency department procedural sedation and analgesia: A Canadian Community Effectiveness and Safety Study (ACCESS).
Topics: Adolescent; Adult; Age Factors; Aged; Apnea; Blood Gas Monitoring, Transcutaneous; Bradycardia; Cana | 2006 |
Influence of cisatracurium on entropy values during propofol-remifentanil anesthesia.
Topics: Aged; Anesthesia, Intravenous; Atracurium; Electromyography; Entropy; Ephedrine; Humans; Hypotension | 2007 |
Intravenous propofol precipitates the hypotension induced by inadvertent epidural thiopental injection.
Topics: Aged; Anesthetics, Intravenous; Drug Synergism; Humans; Hypotension; Injections, Epidural; Male; Med | 2006 |
Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report.
Topics: Acidosis; Anesthetics, Intravenous; Aneurysm; Balloon Occlusion; Cardiac Output, Low; Carotid Artery | 2007 |
[Anesthesia for laparoscopic adrenalectomy in a pregnant patient with Cushing syndrome].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2007 |
Efficacy, safety and patient satisfaction of propofol for procedural sedation and analgesia in the emergency department: a prospective study.
Topics: Conscious Sedation; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Hypotensio | 2007 |
Efficacy, safety and patient satisfaction of propofol for procedural sedation and analgesia in the emergency department: a prospective study.
Topics: Conscious Sedation; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Hypotensio | 2007 |
Efficacy, safety and patient satisfaction of propofol for procedural sedation and analgesia in the emergency department: a prospective study.
Topics: Conscious Sedation; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Hypotensio | 2007 |
Efficacy, safety and patient satisfaction of propofol for procedural sedation and analgesia in the emergency department: a prospective study.
Topics: Conscious Sedation; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Hypotensio | 2007 |
Hypotension in anaesthetized patients during aneurysm clipping: not as bad as expected?
Topics: Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Atracurium; Cohort Studies; Etomidate; Fem | 2008 |
Inhibitory effects of propofol on catecholamine secretion and uptake in cultured bovine adrenal medullary cells.
Topics: Adrenal Medulla; Anesthetics, Intravenous; Animals; Blood Pressure; Calcium; Carbachol; Cattle; Cell | 1996 |
Prevention of hypotension after propofol for rapid sequence intubation.
Topics: Anesthetics, Intravenous; Humans; Hypotension; Propofol | 1996 |
Propofol inhibits medullary pressor mechanisms in cats.
Topics: Anesthetics, Intravenous; Animals; Arteries; Blood Pressure; Cats; Dose-Response Relationship, Drug; | 1997 |
The effect of rate of administration on brain concentrations of propofol in sheep.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Area Under Curve; Brain; Cerebrovascular | 1998 |
Effects of target-controlled anesthesia with propofol and sufentanil on the hemodynamic response to Mayfield head holder application.
Topics: Adjuvants, Anesthesia; Alprazolam; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intra | 1998 |
Anaphylactoid reaction induced by pancuronium during general anaesthesia.
Topics: Aged; Anaphylaxis; Anesthesia, Intravenous; Anesthetics, Intravenous; Bronchial Spasm; Humans; Hypot | 1998 |
Propofol anesthesia for invasive procedures in ambulatory and hospitalized children: experience in the pediatric intensive care unit.
Topics: Adult; Age Factors; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics, Intravenou | 1999 |
The haemodynamic effects of propofol in combination with ephedrine in elderly patients (ASA groups 3 and 4).
Topics: Adrenergic Agents; Aged; Anesthetics, Intravenous; Blood Pressure; Ephedrine; Heart Rate; Hemodynami | 1999 |
Disposition of propofol between red blood cells, plasma, brain and cerebrospinal fluid in rabbits.
Topics: Acidosis; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Intravenous; Animals; Brain | 2000 |
Prospective evaluation of propofol anesthesia in the pediatric intensive care unit for elective oncology procedures in ambulatory and hospitalized children.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Biopsy, Needle; Bone Marrow Ex | 2000 |
Propofol or thiopentone as induction agents in romifidine-sedated and halothane-N2O-anesthetized dogs: a preliminary study.
Topics: Anesthesia, General; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dogs; | 2000 |
[Premedication and sedation complications during ophthalmic anesthesia].
Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anesthesi | 2000 |
Bronchoscopy with bronchoalveolar lavage via the laryngeal mask airway in high-risk hypoxemic immunosuppressed patients.
Topics: Aged; Anesthetics, Intravenous; Blood Gas Analysis; Bronchoalveolar Lavage; Bronchoscopy; Contraindi | 2001 |
[Carotid endarterectomy under remifentanil].
Topics: Aged; Aged, 80 and over; Alprazolam; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetic | 2001 |
Sedation for endoscopy: the safe use of propofol by general practitioner sedationists.
Topics: Anesthetics, Combined; Anesthetics, Intravenous; Australia; Colonoscopy; Family Practice; Fentanyl; | 2002 |
Arterial baroreflex attenuation during and after continuous propofol infusion.
Topics: Animals; Arteries; Blood Pressure; Heart Rate; Hypertension; Hypotension; Infusions, Intravenous; In | 1992 |
Amiodarone and anaesthesia: concurrent therapy with ACE inhibitors--an additional cause for concern?
Topics: Adult; Amiodarone; Anesthesia, Intravenous; Enalapril; Fentanyl; Humans; Hypotension; Male; Midazola | 1991 |
Exaggerated physiological responses to propofol in myotonic dystrophy.
Topics: Anesthesia, General; Humans; Hypotension; Myotonic Dystrophy; Propofol; Surgical Procedures, Operati | 1990 |
Propofol: a new intravenous anaesthetic.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Apnea; Female; Humans; Hypotension; Middle Aged; P | 1988 |