propofol has been researched along with Hypertriglyceridemia in 29 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Hypertriglyceridemia: A condition of elevated levels of TRIGLYCERIDES in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess safety and efficacy of propofol and thiopental for refractory status epilepticus (RSE) in children, the authors reviewed 34 episodes of RSE." | 9.11 | Propofol and thiopental for refractory status epilepticus in children. ( Blussé van Oud-Alblas, HJ; Braun, KP; Malingré, M; van Gestel, JP; van Nieuwenhuizen, O; Ververs, FF, 2005) |
| " Compared to earlier case reports in the literature, recently published cases describe older patients developing PRIS at lower doses of propofol, in whom arrhythmia, hypertriglyceridaemia and fever are less frequently seen, with survival more likely." | 8.91 | Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports. ( Anděl, M; Duška, F; Krajčová, A; Waldauf, P, 2015) |
| "The incidence and risk factors for propofol-associated hypertriglyceridemia (HTG) in patients receiving extracorporeal membrane oxygenation (ECMO) have not been evaluated." | 8.31 | Propofol-Associated Hypertriglyceridemia in Adults With Acute Respiratory Distress Syndrome on Extracorporeal Membrane Oxygenation. ( Erkanli, A; Kim, H; Ohman, K; Parish, A; Rackley, CR; Schultheis, J; Stallworth, S, 2023) |
| "Propofol infusion syndrome (PRIS), a rare complication of propofol sedation, is associated with high mortality." | 7.81 | Therapeutic plasma exchange as treatment for propofol infusion syndrome. ( Levin, PD; Levin, V; Rund, D; Sprung, CL; Weissman, C, 2015) |
| "Propofol can cause acute pancreatitis related to hypertriglyceridemia, however, other mechanisms may also exist." | 7.78 | Hypertriglyceridemia independent propofol-induced pancreatitis. ( Aslanian, HR; Muniraj, T, 2012) |
| "To characterize the frequency, severity, risk factors, and clinician response to propofol-associated hypertriglyceridemia and hypertriglyceridemia-associated pancreatitis." | 7.73 | Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: an analysis of frequency and risk factors. ( Devlin, JW; Lau, AK; Tanios, MA, 2005) |
| "We report a case of pancreatitis, which occurred while the patient was on a propofol drip and then recurred after resolution following an inadvertent rechallenge with propofol." | 7.70 | Propofol-induced pancreatitis: recurrence of pancreatitis after rechallenge. ( Kumar, AN; Lim, KG; Schwartz, DE, 1999) |
| "Reports of intraoperative lipemia during propofol anesthesia are very rare but raise concerns about the safety of prolonged propofol infusion." | 5.40 | Hypertriglyceridemia, lipemia, and elevated liver enzymes associated with prolonged propofol anesthesia for craniotomy. ( Bowdle, A; Gabikian, P; Lee, L; Richebe, P; Rostomily, R, 2014) |
| "To assess safety and efficacy of propofol and thiopental for refractory status epilepticus (RSE) in children, the authors reviewed 34 episodes of RSE." | 5.11 | Propofol and thiopental for refractory status epilepticus in children. ( Blussé van Oud-Alblas, HJ; Braun, KP; Malingré, M; van Gestel, JP; van Nieuwenhuizen, O; Ververs, FF, 2005) |
| "The new propofol 2% preparation is an effective sedative agent and is safe because of the low frequency of associated hypertriglyceridemia." | 5.09 | Pharmacoeconomic assessment of propofol 2% used for prolonged sedation. ( Barrientos-Vega, R; Castellano-Hernández, M; Cuena-Boy, R; Morales-Garcia, C; Sánchez-Soria, MM, 2001) |
| " Compared to earlier case reports in the literature, recently published cases describe older patients developing PRIS at lower doses of propofol, in whom arrhythmia, hypertriglyceridaemia and fever are less frequently seen, with survival more likely." | 4.91 | Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports. ( Anděl, M; Duška, F; Krajčová, A; Waldauf, P, 2015) |
| "The majority of cases (8/11) are related to propofol use leading to hypertriglyceridemia." | 4.31 | Hypertriglyceridemia as a Cause of Continuous Renal Replacement Therapy Circuit Clotting: A Case Series. ( Abo-Zed, A; Abramovitz, BW; DeSilva, R; Oguntuwase, E, 2023) |
| "Propofol infusion syndrome (PRIS), a rare complication of propofol sedation, is associated with high mortality." | 3.81 | Therapeutic plasma exchange as treatment for propofol infusion syndrome. ( Levin, PD; Levin, V; Rund, D; Sprung, CL; Weissman, C, 2015) |
| "Propofol can cause acute pancreatitis related to hypertriglyceridemia, however, other mechanisms may also exist." | 3.78 | Hypertriglyceridemia independent propofol-induced pancreatitis. ( Aslanian, HR; Muniraj, T, 2012) |
| "To characterize the frequency, severity, risk factors, and clinician response to propofol-associated hypertriglyceridemia and hypertriglyceridemia-associated pancreatitis." | 3.73 | Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: an analysis of frequency and risk factors. ( Devlin, JW; Lau, AK; Tanios, MA, 2005) |
| "We report a case of pancreatitis, which occurred while the patient was on a propofol drip and then recurred after resolution following an inadvertent rechallenge with propofol." | 3.70 | Propofol-induced pancreatitis: recurrence of pancreatitis after rechallenge. ( Kumar, AN; Lim, KG; Schwartz, DE, 1999) |
| "Propofol is a potent intravenous anesthetic agent that rapidly induces sedation and unconsciousness." | 2.47 | Clinical effects and lethal and forensic aspects of propofol. ( Levy, RJ, 2011) |
| "Propofol is an appealing agent for ICU sedation due to it's pharmacokinetic profile and a reduced propensity to result in prolonged sedation." | 2.46 | Optimizing sustained use of sedation in mechanically ventilated patients: focus on safety. ( Arnold, HM; Hollands, JM; Mice, ST; Skrupky, LP, 2010) |
| "Propofol was infused at 1." | 1.91 | Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS. ( Babu, VK; Garcia-Fernandez, A; Perez Del Nogal, G; Rojas, P, 2023) |
| "Reports of intraoperative lipemia during propofol anesthesia are very rare but raise concerns about the safety of prolonged propofol infusion." | 1.40 | Hypertriglyceridemia, lipemia, and elevated liver enzymes associated with prolonged propofol anesthesia for craniotomy. ( Bowdle, A; Gabikian, P; Lee, L; Richebe, P; Rostomily, R, 2014) |
| "Propofol is a lipid-based sedative that provides 1." | 1.29 | Pharmacologic influence on nutrition support therapy: use of propofol in a patient receiving combined enteral and parenteral nutrition support. ( Brown, RO; Dickerson, RN; Dunlap, AW; Kudsk, KA; Lowrey, TS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (24.14) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 12 (41.38) | 24.3611 |
| 2020's | 6 (20.69) | 2.80 |
| Authors | Studies |
|---|---|
| El Nekidy, WS | 1 |
| Shatnawei, A | 1 |
| Abdelsalam, MM | 1 |
| Hassan, M | 1 |
| Dajani, RZ | 1 |
| Salem, N | 1 |
| St John, TJL | 1 |
| Rahman, N | 1 |
| Hamed, F | 1 |
| Mallat, J | 1 |
| Babu, VK | 1 |
| Rojas, P | 1 |
| Perez Del Nogal, G | 1 |
| Garcia-Fernandez, A | 1 |
| Abramovitz, BW | 1 |
| Oguntuwase, E | 1 |
| Abo-Zed, A | 1 |
| DeSilva, R | 1 |
| Stallworth, S | 1 |
| Ohman, K | 1 |
| Schultheis, J | 1 |
| Parish, A | 1 |
| Erkanli, A | 1 |
| Kim, H | 1 |
| Rackley, CR | 1 |
| Samal, S | 1 |
| Singhania, N | 1 |
| Adl, D | 1 |
| Afzal, O | 1 |
| Singhania, G | 1 |
| Sharma, B | 1 |
| Diaz Milian, R | 1 |
| Diaz Galdo, R | 1 |
| Castresana, MR | 1 |
| Bassi, E | 1 |
| Ferreira, CB | 1 |
| Macedo, E | 1 |
| Malbouisson, LM | 1 |
| Bowdle, A | 1 |
| Richebe, P | 1 |
| Lee, L | 1 |
| Rostomily, R | 1 |
| Gabikian, P | 1 |
| Levin, PD | 1 |
| Levin, V | 1 |
| Weissman, C | 1 |
| Sprung, CL | 1 |
| Rund, D | 1 |
| Krajčová, A | 1 |
| Waldauf, P | 1 |
| Anděl, M | 1 |
| Duška, F | 1 |
| Pradhan, D | 1 |
| Sun, Q | 1 |
| Peck Palmer, OM | 1 |
| Zaccheo, MM | 1 |
| Bucher, DH | 1 |
| Cottle, D | 1 |
| Boxall, E | 1 |
| Protheroe, R | 1 |
| Kishen, R | 1 |
| Arnold, HM | 1 |
| Hollands, JM | 1 |
| Skrupky, LP | 1 |
| Mice, ST | 1 |
| Levy, RJ | 1 |
| Telletxea, S | 1 |
| Lauzirika, Z | 1 |
| Etxebarria, A | 1 |
| Ortega, LF | 1 |
| Muniraj, T | 1 |
| Aslanian, HR | 1 |
| Devaud, JC | 1 |
| Berger, MM | 1 |
| Pannatier, A | 1 |
| Marques-Vidal, P | 1 |
| Tappy, L | 1 |
| Rodondi, N | 1 |
| Chiolero, R | 1 |
| Voirol, P | 1 |
| van Gestel, JP | 1 |
| Blussé van Oud-Alblas, HJ | 1 |
| Malingré, M | 1 |
| Ververs, FF | 1 |
| Braun, KP | 1 |
| van Nieuwenhuizen, O | 1 |
| Devlin, JW | 1 |
| Lau, AK | 1 |
| Tanios, MA | 1 |
| Mateu, J | 1 |
| Barrachina, F | 3 |
| Barrientos-Vega, R | 2 |
| Mar Sánchez-Soria, M | 1 |
| Morales-García, C | 2 |
| Robas-Gómez, A | 1 |
| Cuena-Boy, R | 2 |
| Ayensa-Rincon, A | 1 |
| Lowrey, TS | 1 |
| Dunlap, AW | 1 |
| Brown, RO | 1 |
| Dickerson, RN | 1 |
| Kudsk, KA | 1 |
| Mateu-de Antonio, J | 2 |
| Kumar, AN | 1 |
| Schwartz, DE | 1 |
| Lim, KG | 1 |
| Sánchez-Soria, MM | 1 |
| Castellano-Hernández, M | 1 |
| Eddleston, JM | 1 |
| Shelly, MP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia[NCT04235894] | 124 participants (Actual) | Observational | 2016-09-07 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for propofol and Hypertriglyceridemia
| Article | Year |
|---|---|
Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports.
Topics: Anesthetics, Intravenous; Arrhythmias, Cardiac; Fever; Heart Failure; Hepatomegaly; Humans; Hypertri | 2015 |
Propofol infusion syndrome: a rare complication with potentially fatal results.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Critical Care; | 2008 |
Optimizing sustained use of sedation in mechanically ventilated patients: focus on safety.
Topics: Bradycardia; Critical Care; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Monitoring; Huma | 2010 |
Clinical effects and lethal and forensic aspects of propofol.
Topics: Accidents; Acidosis; Acute Kidney Injury; Bacteremia; Bradycardia; Drug Overdose; Dyslipidemias; For | 2011 |
[Fospropofol: A new prodrug of propofol].
Topics: Adult; Anesthetics; Biological Availability; Biotransformation; Clinical Trials, Phase III as Topic; | 2012 |
3 trials available for propofol and Hypertriglyceridemia
| Article | Year |
|---|---|
Propofol and thiopental for refractory status epilepticus in children.
Topics: Anticonvulsants; Child; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Sc | 2005 |
Prolonged sedation of critically ill patients with midazolam or propofol: impact on weaning and costs.
Topics: Adult; Aged; Critical Care; Critical Illness; Drug Costs; Female; Hospitals, Community; Humans; Hype | 1997 |
Pharmacoeconomic assessment of propofol 2% used for prolonged sedation.
Topics: Aged; Chemistry, Pharmaceutical; Cohort Studies; Conscious Sedation; Cost-Benefit Analysis; Drug Cos | 2001 |
21 other studies available for propofol and Hypertriglyceridemia
| Article | Year |
|---|---|
Hypertriglyceridemia in Critically Ill Patients With SARS-CoV-2 Infection.
Topics: Adult; COVID-19; Critical Illness; Female; Humans; Hypertriglyceridemia; Intensive Care Units; Lipas | 2022 |
Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS.
Topics: Acidosis; Aged; COVID-19; Humans; Hyperlipidemias; Hypertriglyceridemia; Male; Propofol; Propofol In | 2023 |
Hypertriglyceridemia as a Cause of Continuous Renal Replacement Therapy Circuit Clotting: A Case Series.
Topics: Acute Kidney Injury; Anticoagulants; Blood Coagulation; Continuous Renal Replacement Therapy; Critic | 2023 |
Propofol-Associated Hypertriglyceridemia in Adults With Acute Respiratory Distress Syndrome on Extracorporeal Membrane Oxygenation.
Topics: Adult; Cohort Studies; Extracorporeal Membrane Oxygenation; Humans; Hypertriglyceridemia; Propofol; | 2023 |
Chocolate milk in CRRT circuit: Propofol induced hypertriglyceridemia.
Topics: Aged; Animals; Continuous Renal Replacement Therapy; Humans; Hypertriglyceridemia; Hypnotics and Sed | 2021 |
Does use of propofol aggravate the inflammatory markers and cause propofol infusion syndrome in intubated cases of severe COVID-19 infections?
Topics: Antibodies, Monoclonal, Humanized; COVID-19 Drug Treatment; Humans; Hypertriglyceridemia; Propofol; | 2021 |
Images in Anesthesiology: A Clogged Dialysis Filter Caused by Severe Acutely Induced Hypertriglyceridemia.
Topics: Acute Disease; Anesthetics, Intravenous; Equipment Failure; Humans; Hypertriglyceridemia; Middle Age | 2018 |
Recurrent clotting of dialysis filter associated with hypertriglyceridemia induced by propofol.
Topics: Acute Kidney Injury; Adult; Equipment Failure; Humans; Hypertriglyceridemia; Hypnotics and Sedatives | 2014 |
Hypertriglyceridemia, lipemia, and elevated liver enzymes associated with prolonged propofol anesthesia for craniotomy.
Topics: Adult; Alanine Transaminase; Anesthetics, Intravenous; Aspartate Aminotransferases; Craniotomy; Drug | 2014 |
Therapeutic plasma exchange as treatment for propofol infusion syndrome.
Topics: Accidents, Traffic; Acidosis, Lactic; Acute Kidney Injury; Adolescent; Anticonvulsants; Biomarkers; | 2015 |
Lipidemia in the Setting of Hemolysis.
Topics: Adult; Color; Drug Stability; Emulsions; Hematologic Tests; Hemolysis; Humans; Hypertriglyceridemia; | 2016 |
Raised triglycerides and propofol infusion in H1N1 patients.
Topics: Adolescent; Adult; Female; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; Influenza A Virus, | 2010 |
Hypertriglyceridemia independent propofol-induced pancreatitis.
Topics: Acute Disease; Aged; Humans; Hypertriglyceridemia; Male; Pancreatitis; Propofol | 2012 |
Hypertriglyceridemia: a potential side effect of propofol sedation in critical illness.
Topics: Aged; Critical Illness; Drug Carriers; Fat Emulsions, Intravenous; Female; Humans; Hypertriglyceride | 2012 |
Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: an analysis of frequency and risk factors.
Topics: Acute Disease; Adult; Aged; Female; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; Intensive | 2005 |
Hypertriglyceridaemia associated with propofol sedation in critically ill patients.
Topics: Adolescent; Adult; Critical Illness; Female; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; | 1996 |
Pharmacologic influence on nutrition support therapy: use of propofol in a patient receiving combined enteral and parenteral nutrition support.
Topics: Adolescent; Critical Illness; Drug Monitoring; Female; Humans; Hypertriglyceridemia; Hypnotics and S | 1996 |
Propofol infusion and nutritional support.
Topics: Drug Carriers; Fat Emulsions, Intravenous; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; Nu | 1997 |
Propofol and hypertriglyceridemia: no problem?
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypertriglyceridemia; Propofol; Triglycerides | 1999 |
Propofol-induced pancreatitis: recurrence of pancreatitis after rechallenge.
Topics: Female; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; Middle Aged; Pancreatitis; Propofol; | 1999 |
The effect on serum lipid concentrations of a prolonged infusion of propofol--hypertriglyceridaemia associated with propofol administration.
Topics: Adolescent; Cholesterol; Cholesterol, HDL; Energy Intake; Fat Emulsions, Intravenous; Humans; Hypert | 1991 |