Page last updated: 2024-11-03

propofol and Hypertension

propofol has been researched along with Hypertension in 83 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"This randomized controlled trial was performed to observe the effect of remimazolam with sufentanil on hemodynamics during anesthetic induction in elderly patients with mild hypertension undergoing orthopedic surgery of the lower limbs."9.69Effects of remimazolam combined with sufentanil on hemodynamics during anesthetic induction in elderly patients with mild hypertension undergoing orthopedic surgery of the lower limbs: a randomized controlled trial. ( Duan, G; Lan, H; Shan, W; Wu, J; Xu, Q, 2023)
"The present study shows that it is preferable to administer 2 μg/kg fentanyl in patients without hypertension and 4 μg/kg fentanyl in patients with hypertension in order to minimize the changes in heart rate, systolic blood pressure and cardiac output associated with tracheal intubation."9.17Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study. ( Kadoi, Y; Miyazaki, M; Sawano, Y; Shimada, H, 2013)
"Hypercapnia, not hypertension, significantly improved cerebral oxygen balance without observed side effects during propofol anesthesia."9.14The effect of hypercapnia and hypertension on cerebral oxygen balance during one-lung ventilation for lung surgery during propofol anesthesia. ( Furuya, H; Inoue, S; Iwata, M; Kawaguchi, M; Kimura, M; Taniguchi, S; Tojo, T, 2010)
"These findings suggest that 5-ALA-HCl does not affect the antihypertensive agents-induced hypotensive effect, but enhances the bupivacaine-induced hypotensive effect, especially in SHRs, indicating that 5-ALA may contribute to anesthesia-induced hypotension via suppression of sympathetic nerve activity in patients with hypertension."8.315-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. ( Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N, 2023)
"This retrospective, matched cohort study evaluated the incidence of rebound hypertension in intensive care unit patients receiving continuous infusions of at least 72 hours in duration of dexmedetomidine, propofol, or midazolam."7.91Incidence of Rebound Hypertension after Discontinuation of Dexmedetomidine. ( Alaniz, C; Flieller, LA; Miller, JT; Pleva, MR, 2019)
"The aim of this paper is to compare baroreflex sensitivity (BRS) following anesthesia induction via propofol to pre-induction baseline values through a systematic and mathematically robust analysis."7.79Baroreflex sensitivity variations in response to propofol anesthesia: comparison between normotensive and hypertensive patients. ( Aletti, F; Canichella, A; Cerutti, S; Coniglione, F; Dauri, M; Dorantes Mendez, G; Ferrario, M; Guerrisi, M; Signorini, MG; Toschi, N, 2013)
" Owing to the lag of knowledge in the above said facts, the objectives of this study were to evaluate the effects of propofol combined with sufentanil on the expression of Bax, BCL-2, and caspase-3 genes in spontaneously hypertensive rats suffering with cerebral hemorrhage."5.91Effects of Propofol Combined with Sufentanil Target-Controlled Intravenous Anesthesia on Expression of Bax, Bcl-2, and Caspase-3 Genes in Spontaneous Hypertensive Rats with Cerebral Hemorrhage: a Prospective Case-Controlled Study. ( Ke, Y; Lei, L; Qiao, X; Siqi, Y, 2023)
"Remimazolam induction was more stable than propofol induction in preserving normal hemodynamics and was associated with a relatively lower incidence of hypotension."5.69Comparison of remimazolam and propofol induction on hemodynamic response in hypertensive patients. ( Choi, EK; Jang, Y; Park, SJ, 2023)
"This randomized controlled trial was performed to observe the effect of remimazolam with sufentanil on hemodynamics during anesthetic induction in elderly patients with mild hypertension undergoing orthopedic surgery of the lower limbs."5.69Effects of remimazolam combined with sufentanil on hemodynamics during anesthetic induction in elderly patients with mild hypertension undergoing orthopedic surgery of the lower limbs: a randomized controlled trial. ( Duan, G; Lan, H; Shan, W; Wu, J; Xu, Q, 2023)
" Evidence of apnea, hypotension, hypertension and hypoxemia were recorded during surgery."5.51Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery. ( Gao, Y; Yan, F, 2022)
"Propofol acts as an L-type calcium channel (LTCC) antagonist to decrease peripheral resistance and initiate hypotension."5.38Role of L-type calcium channels in altered microvascular responses to propofol in hypertension. ( Brookes, ZL; Brown, NJ; Lawton, BK; Reilly, CS, 2012)
"Pharmacologic angiotensin axis blockade (AAB) has been associated with profound hypotension following anesthetic induction with propofol."5.30A randomized controlled trial comparing methohexital and propofol for induction in patients receiving angiotensin axis blockade. ( Adhikary, S; Bonavia, A; Budde, A; Kunselman, A; Lyn-Sue, J; Mets, B; Verbeek, T, 2019)
"The present study shows that it is preferable to administer 2 μg/kg fentanyl in patients without hypertension and 4 μg/kg fentanyl in patients with hypertension in order to minimize the changes in heart rate, systolic blood pressure and cardiac output associated with tracheal intubation."5.17Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study. ( Kadoi, Y; Miyazaki, M; Sawano, Y; Shimada, H, 2013)
"Our study showed that the use of propofol resulted in less hypertension and tachycardia at and after intubation than etomidate."5.17Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial. ( Kamenik, M; Möller Petrun, A, 2013)
"Hypercapnia, not hypertension, significantly improved cerebral oxygen balance without observed side effects during propofol anesthesia."5.14The effect of hypercapnia and hypertension on cerebral oxygen balance during one-lung ventilation for lung surgery during propofol anesthesia. ( Furuya, H; Inoue, S; Iwata, M; Kawaguchi, M; Kimura, M; Taniguchi, S; Tojo, T, 2010)
"Propofol induction reduced the sympathetic activation and hypertension associated with desflurane."5.09Propofol, but not etomidate, reduces desflurane-mediated sympathetic activation in humans. ( Ebert, TJ; Lopatka, CW; Muzi, M, 1999)
"Using high doses of propofol rather than moderate doses in combination with nitroprusside in coronary surgery does not improve control of either hypertension or hemodynamic stability."5.08[Treatment of the hypertensive response during coronary surgery: comparison of high-dose propofol to propofol with nitroprusside]. ( Ballester, JA; Guijarrubia, EG; Maestro, B; Olmos, M; Vidarte, MA, 1998)
" There was no difference in the incidence of breakthrough hypertension between the two groups (in 44% and 43% of the patients, respectively) and in the number of alfentanil bolus supplements."5.08Continuous infusions of alfentanil and propofol for coronary artery surgery. ( de Lange, S; Gerrits, HJ; Roekaerts, PM; Timmerman, BE, 1995)
"These findings suggest that 5-ALA-HCl does not affect the antihypertensive agents-induced hypotensive effect, but enhances the bupivacaine-induced hypotensive effect, especially in SHRs, indicating that 5-ALA may contribute to anesthesia-induced hypotension via suppression of sympathetic nerve activity in patients with hypertension."4.315-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. ( Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N, 2023)
"This retrospective, matched cohort study evaluated the incidence of rebound hypertension in intensive care unit patients receiving continuous infusions of at least 72 hours in duration of dexmedetomidine, propofol, or midazolam."3.91Incidence of Rebound Hypertension after Discontinuation of Dexmedetomidine. ( Alaniz, C; Flieller, LA; Miller, JT; Pleva, MR, 2019)
"Propofol anesthesia is usually accompanied by hypotension."3.88Angiotensin converting enzyme inhibitors enhance the hypotensive effects of propofol by increasing nitric oxide production. ( Ferreira, GC; Garcia, LV; Garcia, WNP; Lacchini, R; Oliveira-Paula, GH; Pinheiro, LC; Tanus-Santos, JE, 2018)
"The aim of this paper is to compare baroreflex sensitivity (BRS) following anesthesia induction via propofol to pre-induction baseline values through a systematic and mathematically robust analysis."3.79Baroreflex sensitivity variations in response to propofol anesthesia: comparison between normotensive and hypertensive patients. ( Aletti, F; Canichella, A; Cerutti, S; Coniglione, F; Dauri, M; Dorantes Mendez, G; Ferrario, M; Guerrisi, M; Signorini, MG; Toschi, N, 2013)
" The aim of the present study was to test the hypothesis that propofol, a widely used intravenous anaesthetic agent, could alter the arterial response to AngII and to evaluate its effect in genetic hypertension."3.72Effect of propofol on vasoconstriction and calcium mobilization induced by Angiotensin II differs in aortas from normotensive and hypertensive rats. ( Bouillier, H; Clichet, A; Dagher, G; Marty, J; Pili-Floury, S; Renaud, JF; Safar, M; Samain, E, 2004)
" The effect of propofol on arterial tone in hypertension is poorly understood."3.71Propofol differently alters vascular reactivity in normotensive and hypertensive rats. ( Bouillier, H; Chamiot-Clerc, P; Clichet, A; Marty, J; Renaud, JF; Safar, M; Samain, E, 2002)
"We have investigated the effects of propofol 50 mumol litre-1 on contractile and relaxant responses in experimental hypertension and assessed endothelial modulation of these responses."3.70Effects of propofol on vascular reactivity in isolated aortae from normotensive and spontaneously hypertensive rats. ( Barale, F; Berthelot, A; Boillot, A; Laurant, P, 1999)
"Forty patients who had undergone coronary artery graft surgery and who required vasodilator therapy for postoperative hypertension were given infusions of either propofol (2,6,di-isopropylphenol) or midazolam, together with an infusion of morphine for analgesia while ventilation was controlled artificially."3.68Sedation after cardiac bypass surgery: comparison of propofol and midazolam in the presence of a computerized closed loop arterial pressure controller. ( Chaudhri, S; Kenny, GN, 1992)
"Remimazolam tosilate (RT) is a new short-acting GABA(A) receptor agonist, having potential to be an effective option for procedural sedation."3.01Remimazolam tosilate in upper gastrointestinal endoscopy: A multicenter, randomized, non-inferiority, phase III trial. ( Bai, H; Bao, HG; Chen, SH; Huang, YG; Ji, FH; Jin, XJ; Li, L; Li, XK; Li, YJ; Luo, AL; Lv, JR; Min, S; Pan, CX; Tian, M; Wang, Q; Wang, S; Yu, YH; Yuan, TM; Zhang, J; Zhong, TD; Zou, XH, 2021)
"Postoperative respiratory depression was defined as rate <10/min, hypercapnia/hypercarbia-arterial CO2 tension >50 mmHg or SO2 <90 while hypotension was defined as a decrease of 20 % in mean blood pressure compared to initial values."2.82Propofol-ketamine combination: a choice with less complications and better hemodynamic stability compared to propofol? On a prospective study in a group of colonoscopy patients. ( Babayıgıt, M; Baykal Tutal, Z; Derelı, N; Gulec, H; Horasanlı, E; Inceoz, H; Kurtay, A, 2016)
"Propofol was adjusted to keep 402.75A beat-by-beat cardiovascular index, CARDEAN: a prospective randomized assessment of its utility for the reduction of movement during colonoscopy. ( Bissery, A; Bourdon, L; Cividjian, A; Escarment, J; Lions, C; Martinez, JY; Puidupin, M; Quintin, L; Rabilloud, M; Wey, PF, 2010)
"Systemic hypertension is a major drawback associated with fast tracking, which may predispose to formation of intracranial hematoma."2.73Planning for early emergence in neurosurgical patients: a randomized prospective trial of low-dose anesthetics. ( Bhagat, H; Bithal, PK; Chouhan, RS; Dash, HH; Pandia, MP, 2008)
"Clonidine was associated with a significant (P < 0."2.69Clonidine and cardiac surgery: haemodynamic and metabolic effects, myocardial ischaemia and recovery. ( Buckland, MR; Bujor, MA; Davis, BB; Esmore, DS; Hall, J; Holdgaard, HO; Hunt, JO; McRae, R; Moloney, J; Morgan, DJ; Myles, PS, 1999)
"The isoflurane-induced increase in rate-pressure product was significantly greater in the thiamylal group than in the propofol group."2.69The effect of propofol and thiamylal on hypertensive responses to a rapid increase in isoflurane concentration. ( Kanaya, N; Nakayama, M; Namiki, A; Tsuchida, H, 1999)
"Halothane anaesthesia was associated with significant reflex tachycardia in response to SNP induced hypotension."2.67Sodium nitroprusside induced hypotension: haemodynamic response and dose requirements during propofol or halothane anaesthesia. ( Abdulatif, M, 1994)
"A 67-year-old woman with hypertension, type 2 diabetes mellitus, and hypothyroidism presented for an elective blepharoplasty."1.91A 67-Year-Old Woman With Fluctuating Hypertension and Hypotension After Elective Surgery. ( Ho, C; Lau, C, 2023)
" Owing to the lag of knowledge in the above said facts, the objectives of this study were to evaluate the effects of propofol combined with sufentanil on the expression of Bax, BCL-2, and caspase-3 genes in spontaneously hypertensive rats suffering with cerebral hemorrhage."1.91Effects of Propofol Combined with Sufentanil Target-Controlled Intravenous Anesthesia on Expression of Bax, Bcl-2, and Caspase-3 Genes in Spontaneous Hypertensive Rats with Cerebral Hemorrhage: a Prospective Case-Controlled Study. ( Ke, Y; Lei, L; Qiao, X; Siqi, Y, 2023)
"Phenobarbital was trialed for possible propofol withdrawal syndrome, allowing for a dose reduction of 10 μg/kg/min within 2 hours of the first dose without any corresponding symptoms."1.91Successful management of suspected propofol dependence with phenobarbital in an adult patient with COVID-19. ( Feeney, ME; Steiling, K, 2023)
"The EBUS-TBNA procedure performed under DS was safe in elderly and young patients."1.91Safety of geriatric patients undergoing endobronchial ultrasound-guided transbronchial needle aspiration with deep sedation: a retrospective study. ( Alagöz, A; Öztürk, A; Sazak, H; Tunç, M; Yılmaz, A, 2023)
"Shock was more common in patients with variceal bleeding compared to those with non-variceal bleeding (12."1.43Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding. ( Eun, CS; Han, DS; Jeon, YC; Jeong, JY; Park, CH; Sohn, JH; Yoo, KS, 2016)
"Hypotension was defined when blood pressure decreased more than or equal to 25 percent compared to blood pressure measured at first in operating room."1.40[Retrospective evaluation of predictors and frequency of hypotension in hypertensive patients after induction of general anesthesia]. ( Ida, M; Iwata, M; Kamiya, T; Kimoto, K; Kuzumoto, N; Nakayama, K; Shimomura, T, 2014)
"Propofol acts as an L-type calcium channel (LTCC) antagonist to decrease peripheral resistance and initiate hypotension."1.38Role of L-type calcium channels in altered microvascular responses to propofol in hypertension. ( Brookes, ZL; Brown, NJ; Lawton, BK; Reilly, CS, 2012)
"To prospectively assess sedation-related adverse events (SRAEs), patient- and procedure-related risk factors associated with SRAEs, and endoscopist and patient satisfaction with anesthesiologist-administered sedation."1.37A prospective assessment of sedation-related adverse events and patient and endoscopist satisfaction in ERCP with anesthesiologist-administered sedation. ( Barnett, SR; Berzin, TM; Chuttani, R; Jakubowski, M; Pleskow, DK; Sanaka, S; Sawhney, MS; Sepe, PS; Sundar, E, 2011)
"Propofol was infused for 24 hours and then was stopped to allow continuing neurological assessment."1.37Accidental intraventricular administration of phenytoin through an external ventricular drain: case report. ( Macneil, C; McConnell, P, 2011)
"This process has been shown to ablate tumors in animal studies."1.36Irreversible electroporation: a new challenge in "out of operating theater" anesthesia. ( Ball, C; Kavnoudias, H; Thomson, KR, 2010)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.20)18.7374
1990's18 (21.69)18.2507
2000's26 (31.33)29.6817
2010's26 (31.33)24.3611
2020's12 (14.46)2.80

Authors

AuthorsStudies
Gao, Y1
Yan, F1
Lau, C1
Ho, C1
Lei, L1
Qiao, X1
Siqi, Y1
Ke, Y1
Fukuda, N1
Katakawa, M1
Ito, H1
Hara, T1
Otsuka, N1
Ishizuka, M1
Abe, M1
Feeney, ME1
Steiling, K1
Liu, Y1
Huang, Y1
Wang, R1
Zhai, Y1
Huang, K1
Ren, Z1
Choi, EK1
Jang, Y1
Park, SJ1
Joe, HB1
Chae, YJ1
Song, SH1
Yi, IK1
Tunç, M1
Sazak, H1
Öztürk, A1
Yılmaz, A1
Alagöz, A1
Xu, Q1
Wu, J1
Shan, W1
Duan, G1
Lan, H1
Chen, J1
Zou, X1
Hu, B1
Yang, Y1
Wang, F1
Zhou, Q1
Shen, M1
Flieller, LA1
Alaniz, C1
Pleva, MR1
Miller, JT1
Chen, SH1
Yuan, TM1
Zhang, J2
Bai, H1
Tian, M1
Pan, CX1
Bao, HG1
Jin, XJ1
Ji, FH1
Zhong, TD1
Wang, Q1
Lv, JR1
Wang, S1
Li, YJ1
Yu, YH1
Luo, AL1
Li, XK1
Min, S1
Li, L1
Zou, XH1
Huang, YG1
Thongrong, C1
Sirikannarat, P1
Kasemsiri, P1
Duangthongphon, P1
Oliveira-Paula, GH1
Pinheiro, LC1
Ferreira, GC1
Garcia, WNP1
Lacchini, R1
Garcia, LV1
Tanus-Santos, JE1
Jor, O1
Maca, J1
Koutna, J1
Gemrotova, M1
Vymazal, T1
Litschmannova, M1
Sevcik, P1
Reimer, P1
Mikulova, V1
Trlicova, M1
Cerny, V1
Bonavia, A1
Verbeek, T1
Adhikary, S1
Kunselman, A1
Budde, A1
Lyn-Sue, J1
Mets, B1
Aydogan, MS1
Yücel, A1
Begec, Z1
Colak, YZ1
Durmus, M1
Ida, M1
Kimoto, K1
Iwata, M2
Nakayama, K1
Kamiya, T1
Kuzumoto, N1
Shimomura, T1
Nitta, Y1
Kamekura, N1
Takuma, S1
Fujisawa, T1
Sitkin, SI1
Davydova, OB1
Kostin, IO1
Gasparian, AL1
Baykal Tutal, Z1
Gulec, H1
Derelı, N1
Babayıgıt, M1
Kurtay, A1
Inceoz, H1
Horasanlı, E1
Park, CH1
Han, DS1
Jeong, JY1
Eun, CS1
Yoo, KS1
Jeon, YC1
Sohn, JH1
Wang, Z1
Ji, Y1
Qian, H1
Dong, N1
Squair, JW1
Phillips, AA1
Harmon, M1
Krassioukov, AV1
Liatsi, D1
Tsapas, B1
Pampori, S1
Tsagourias, M1
Pneumatikos, I1
Matamis, D1
Bhagat, H1
Dash, HH1
Bithal, PK1
Chouhan, RS1
Pandia, MP1
Imanaka, N1
Nakasuji, M1
Nomura, M1
Higuchi, M1
Nakamura, M1
Tanaka, M1
Kawashima, H1
Castellani, G1
Zweifel, C1
Kim, DJ1
Carrera, E1
Radolovich, DK1
Smielewski, P1
Hutchinson, PJ1
Pickard, JD1
Czosnyka, M1
Ferreira, DA1
Nunes, CS1
Lobo, F1
Antunes, LM1
Amorim, P1
Ball, C1
Thomson, KR1
Kavnoudias, H1
Martinez, JY1
Wey, PF1
Lions, C1
Cividjian, A1
Rabilloud, M1
Bissery, A1
Bourdon, L1
Puidupin, M1
Escarment, J1
Quintin, L1
Hegde, HV1
Puri, GD1
Fiehn, A1
Weisenberg, M1
Sessler, DI1
Tavdi, M1
Gleb, M1
Ezri, T1
Dalton, JE1
Protianov, M1
Zimlichmann, R1
Inoue, S1
Kawaguchi, M1
Kimura, M1
Tojo, T1
Taniguchi, S1
Furuya, H1
Berzin, TM1
Sanaka, S1
Barnett, SR1
Sundar, E1
Sepe, PS1
Jakubowski, M1
Pleskow, DK1
Chuttani, R1
Sawhney, MS1
Fernández Suárez, FE1
Argüelles Tamargo, L1
González Alvarez, A1
McConnell, P1
Macneil, C1
Lawton, BK1
Brown, NJ2
Reilly, CS2
Brookes, ZL2
Jensen, JT1
Banning, AM1
Clementsen, P1
Hammering, A1
Hornslet, P1
Horsted, T1
Vilmann, P1
Möller Petrun, A1
Kamenik, M1
Sawano, Y1
Miyazaki, M1
Shimada, H1
Kadoi, Y1
Dorantes Mendez, G1
Aletti, F1
Toschi, N1
Canichella, A1
Dauri, M1
Coniglione, F1
Guerrisi, M1
Signorini, MG1
Cerutti, S1
Ferrario, M1
Samain, E3
Clichet, A2
Bouillier, H3
Chamiot-Clerc, P1
Safar, M3
Marty, J3
Renaud, JF2
Jianqing, X1
Juesheng, W1
Ailun, L1
Zhenxin, Z1
Kanaide, M1
Fukusaki, M1
Tamura, S1
Takada, M1
Miyako, M1
Sumikawa, K1
Okamoto, T1
Minami, K1
Pili-Floury, S1
Dagher, G2
Kulkarni, A1
Price, G1
Saxena, M1
Skowronski, G1
Shafiq, B1
Zuckerman, RL1
Queale, WS1
Cosgarea, AJ1
Grabowska-Gaweł, A1
Wiśniewski, J1
Shibata, S1
Matsunaga, M1
Oikawa, M1
Nitahara, K1
Higa, K1
Stephens, LC1
Katz, SG1
Cillo, JE1
Finn, R1
Hack, H1
Isik, A1
Taydas, E1
Ulukaya, S1
Balcioglu, T1
Aydin, U1
Kilic, M1
Rassam, S1
Shah, S1
Sangari, T1
Qasim, M1
Martin, T1
Mutch, WA1
White, IW1
Donen, N1
Thomson, IR1
Rosenbloom, M1
Cheang, M1
West, M1
Roekaerts, PM1
Gerrits, HJ1
Timmerman, BE1
de Lange, S1
Abboud, TK1
Zhu, J1
Richardson, M1
Peres Da Silva, E1
Donovan, M1
Gordon, PC1
Morrell, DF1
Pamm, JD1
Nitschke, T1
Abdulatif, M1
Webb, TB1
Rouse, EC1
Wei, TT1
Lin, CF1
Igarashi, M2
Nishikawa, K1
Nakayama, M2
Sato, K1
Kita, A1
Tsunoda, K2
Tsuchida, H2
Namiki, A3
Olmos, M1
Guijarrubia, EG1
Maestro, B1
Ballester, JA1
Vidarte, MA1
Myles, PS1
Hunt, JO1
Holdgaard, HO1
McRae, R1
Buckland, MR1
Moloney, J1
Hall, J1
Bujor, MA1
Esmore, DS1
Davis, BB1
Morgan, DJ1
Lopatka, CW1
Muzi, M1
Ebert, TJ1
Kanaya, N1
Masuda, T1
Jinnouchi, Y1
Kitahata, H1
Kimura, H1
Oshita, S1
Yamauchi, M1
Edanaga, M1
Suzuki, H1
Tohdoh, Y1
Boillot, A1
Laurant, P1
Berthelot, A1
Barale, F1
Mavoungou, P1
Billard, V1
Moussaud, R1
Potiron, L1
Renfrew, C1
Dickson, R1
Schwab, C1
Albertin, A1
Casati, A1
Deni, F1
Danelli, G1
Comotti, L1
Grifoni, F1
Fanelli, G1
Nathan, N1
Vial, G1
Benrhaiem, M1
Peyclit, A1
Feiss, P1
Kamijo, Y1
Goto, H1
Nakazawa, K1
Benson, KT1
Arakawa, K1
Chaudhri, S1
Kenny, GN1
Littler, C1
McConachie, I1
Healy, TE1

Clinical Trials (19)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Investigation of the Dose Range of Remimazolam Besylate in Different Age Groups of Adults and Its Effects on Hemodynamics[NCT06009991]1,876 participants (Anticipated)Interventional2023-07-17Recruiting
Effects of Propofol Titration at Different Speeds on Hemodynamics and Stress During General Anesthesia Induction[NCT04595591]276 participants (Actual)Interventional2020-10-23Completed
Observational Study to Evaluate the Pressure Recording Analytical Method Parameters in Patients Susceptible to Post-induction Hypotension Due to Hypertension, Diabetes Mellitus, Cardiovascular Risk Factors, or Major Surgery[NCT05960604]660 participants (Anticipated)Observational2023-12-25Not yet recruiting
Different Types of Intraoperative Hypotension and Their Association With Post-anesthesia Care Unit Recovery[NCT05671783]4,776 participants (Actual)Observational2022-05-06Completed
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886]8 participants (Anticipated)Interventional2021-06-08Recruiting
The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388]46 participants (Anticipated)Interventional2020-02-01Not yet recruiting
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923]8 participants (Anticipated)Interventional2021-12-31Recruiting
Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury[NCT05111093]20 participants (Anticipated)Interventional2021-11-29Recruiting
Effect of Clonidine vs. Dexmedetomidine in Addition to Standard Treatment in Agitated Delirium in Intensive Care Patients: Pilot Study.[NCT04758936]Phase 450 participants (Anticipated)Interventional2021-02-01Recruiting
Effects of Dexmedetomidine on Anaesthesia During IRE Procedures for Solid Tumours[NCT02044224]Phase 430 participants (Anticipated)Interventional2014-01-31Completed
Studio Clinico Pilota Con Uso di Elettroporazione Irreversibile (IRE) Nel Trattamento di Lesioni Neoplastiche Epatiche Con Localizzazione ad accessibilità Limitata o ad Alto Rischio[NCT01442324]5 participants (Anticipated)Interventional2011-02-28Recruiting
The Study of Ciprofol for the Suppression of Cardiovascular Responses to Tracheal[NCT06095570]Phase 4150 participants (Anticipated)Interventional2022-07-23Recruiting
Randomized. Controlled Trial of the Utilization of High Flow Nasal Cannula for Oxygenation of Sedated Morbidly Obese Patients in the Endoscopy Suite[NCT02859597]41 participants (Actual)Interventional2016-12-28Completed
Comparison of Leg Elevation and Leg Wrapping in the Prevention of Propofol Induced Hypotension: A Prospective Randomised Controlled Study[NCT02845921]150 participants (Anticipated)Interventional2016-01-31Recruiting
Comparison of the Effects of Total Intravenous Anesthesia and Inhalation Anesthesia on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and the Mechanism Involved: a Single-center, Randomized, Prospective Study[NCT03193710]260 participants (Anticipated)Observational2017-09-01Recruiting
Use of Airway Pressure Release Ventilation in Morbidly Obese Patients Undergoing Open Heart Surgery to Improve Post Operative Pulmonary Outcomes[NCT05670483]60 participants (Anticipated)Interventional2022-12-03Recruiting
Optimal Dose of Intravenous Oxycodone for Attenuation of Hemodynamic[NCT02484352]Phase 495 participants (Actual)Interventional2015-07-31Completed
The Hemodynamic Response to Endotracheal Intubation at Different Time of Fentanyl Given During Induction: a Randomized Controlled Trial[NCT03728686]101 participants (Actual)Interventional2016-12-16Completed
Comparison of Hemodynamic Changes After Endotracheal Intubation by Using the Videolaryngoscope and the Macintosh Direct Laryngoscope in Elderly Hypertensive Patients[NCT02564640]100 participants (Actual)Interventional2015-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Ability to Maintain Oxygenation

The ease at which the Anesthesiologist is able to maintain adequate oxygenation during the period of sedation required for the procedure. the ability of each oxygen device to maintain oxygenation was based on the number of manipulations; more manipulations, the device is less effective at maintaining saturation for this population. (NCT02859597)
Timeframe: During the period of sedation, on average up to 1 hour

Interventionmanipulations (Mean)
High Flow Nasal Canula0.55
Nasal Canula0.61

Number of Participants Requiring Airway Adjuncts During Procedure

The use of airway adjuncts such as oral and nasal airways to insure adequate oxygenation during procedure. (NCT02859597)
Timeframe: During the period of sedation, on average up to 1 hour

InterventionParticipants (Count of Participants)
High Flow Nasal Cannula0
Nasal Cannula0

Number of Participants Who Need an Increase in Fraction of Inspired Oxygen

Need to increase the FiO2 to maintain adequate oxygenation (NCT02859597)
Timeframe: During period of sedation, on average up to 1 hour

InterventionParticipants (Count of Participants)
High Flow Nasal Canula6
Nasal Canula3

Trials

36 trials available for propofol and Hypertension

ArticleYear
Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery.
    Current drug metabolism, 2022, Volume: 23, Issue:1

    Topics: Anesthesia; Apnea; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Hypotension; Hypo

2022
Sedation with a 1:1 mixture of etomidate and propofol for gastroscopy in hypertensive elderly patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:8

    Topics: Aged; Anesthetics, Intravenous; Etomidate; Gastroscopy; Humans; Hypertension; Propofol; Prospective

2023
Comparison of remimazolam and propofol induction on hemodynamic response in hypertensive patients.
    Medicine, 2023, Jul-28, Volume: 102, Issue:30

    Topics: Anesthesia, General; Hemodynamics; Humans; Hypertension; Hypotension; Propofol

2023
Comparison of the effects of dexmedetomidine and propofol on the cardiovascular autonomic nervous system during spinal anesthesia: preliminary randomized controlled observational study.
    Journal of clinical monitoring and computing, 2023, Volume: 37, Issue:6

    Topics: Anesthesia, Spinal; Autonomic Nervous System; Dexmedetomidine; Humans; Hypertension; Hypnotics and S

2023
Effects of remimazolam combined with sufentanil on hemodynamics during anesthetic induction in elderly patients with mild hypertension undergoing orthopedic surgery of the lower limbs: a randomized controlled trial.
    BMC anesthesiology, 2023, 09-14, Volume: 23, Issue:1

    Topics: Aged; Anesthetics; Hemodynamics; Humans; Hypertension; Lower Extremity; Orthopedic Procedures; Propo

2023
Remimazolam vs Etomidate: Haemodynamic Effects in Hypertensive Elderly Patients Undergoing Non-Cardiac Surgery.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Aged; Anesthesia, General; Etomidate; Hemodynamics; Humans; Hypertension; Myoclonus; Pain; Propofol;

2023
Remimazolam tosilate in upper gastrointestinal endoscopy: A multicenter, randomized, non-inferiority, phase III trial.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:2

    Topics: Adult; Aged; Anesthesia Recovery Period; Benzodiazepines; Conscious Sedation; Endoscopy, Gastrointes

2021
Comparison of dexmedetomidine and fentanyl to prevent haemodynamic response to skull pin application in neurosurgery: double blind randomized controlled trial.
    Anaesthesiology intensive therapy, 2017, Volume: 49, Issue:4

    Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Bone Nails; Craniotomy; Dexmedetomidine; Double-Bli

2017
A randomized controlled trial comparing methohexital and propofol for induction in patients receiving angiotensin axis blockade.
    Medicine, 2019, Volume: 98, Issue:5

    Topics: Aged; Anesthesia; Anesthetics, Intravenous; Angiotensin II; Angiotensin Receptor Antagonists; Angiot

2019
[Use of analgesia and sedation in dental implantology in patients with concomitant hypertension].
    Stomatologiia, 2015, Volume: 94, Issue:1

    Topics: Anesthesia, Dental; Anesthesia, Local; Blood Pressure; Conscious Sedation; Dental Implantation; Fema

2015
Propofol-ketamine combination: a choice with less complications and better hemodynamic stability compared to propofol? On a prospective study in a group of colonoscopy patients.
    Irish journal of medical science, 2016, Volume: 185, Issue:3

    Topics: Anesthetics, Combined; Colonoscopy; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; H

2016
Planning for early emergence in neurosurgical patients: a randomized prospective trial of low-dose anesthetics.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure

2008
Remifentanil bolus dose is a safe procedure to control intense noxious stimuli in hypertensive neurosurgical patients.
    Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:11

    Topics: Adult; Analgesics, Opioid; Area Under Curve; Consciousness Monitors; Demography; Dose-Response Relat

2009
A beat-by-beat cardiovascular index, CARDEAN: a prospective randomized assessment of its utility for the reduction of movement during colonoscopy.
    Anesthesia and analgesia, 2010, Mar-01, Volume: 110, Issue:3

    Topics: Adult; Alfentanil; Algorithms; Analgesics, Opioid; Anesthetics, Intravenous; Blood Pressure; Blood P

2010
Dose-dependent hemodynamic effects of propofol induction following brotizolam premedication in hypertensive patients taking angiotensin-converting enzyme inhibitors.
    Journal of clinical anesthesia, 2010, Volume: 22, Issue:3

    Topics: Adult; Aged; Anesthetics, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Azepines; Blood Pre

2010
The effect of hypercapnia and hypertension on cerebral oxygen balance during one-lung ventilation for lung surgery during propofol anesthesia.
    Journal of clinical anesthesia, 2010, Volume: 22, Issue:8

    Topics: Aged; Anesthetics, Intravenous; Brain; Cerebrovascular Circulation; Female; Humans; Hypercapnia; Hyp

2010
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
    British journal of anaesthesia, 2013, Volume: 110, Issue:3

    Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P

2013
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
    British journal of anaesthesia, 2013, Volume: 110, Issue:3

    Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P

2013
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
    British journal of anaesthesia, 2013, Volume: 110, Issue:3

    Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P

2013
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
    British journal of anaesthesia, 2013, Volume: 110, Issue:3

    Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Optimal fentanyl dosage for attenuating systemic hemodynamic changes, hormone release and cardiac output changes during the induction of anesthesia in patients with and without hypertension: a prospective, randomized, double-blinded study.
    Journal of anesthesia, 2013, Volume: 27, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Double-Blind Method; Fentanyl; Heart

2013
Hemodynamic and catecholamine responses during tracheal intubation using a lightwand device (Trachlight) in elderly patients with hypertension.
    Journal of anesthesia, 2003, Volume: 17, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Catecholamines; Electrocardiography; Female; Fentany

2003
[Effects of modified anaesthesia for patients undergoing brain artery aneurysm repair operation].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 17, Issue:99

    Topics: Anesthesia, General; Anesthetics, Intravenous; Carbon Dioxide; Female; Fentanyl; Humans; Hydrotherap

2004
Haemodynamic instability and myocardial ischaemia during carotid endarterectomy: a comparison of propofol and isoflurane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:7

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

1995
Continuous infusions of alfentanil and propofol for coronary artery surgery.
    Journal of cardiothoracic and vascular anesthesia, 1995, Volume: 9, Issue:4

    Topics: Alfentanil; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Coron

1995
Intravenous propofol vs thiamylal-isoflurane for caesarean section, comparative maternal and neonatal effects.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:2

    Topics: Acid-Base Equilibrium; Adaptation, Physiological; Adult; Anesthesia, Inhalation; Anesthesia, Intrave

1995
Sodium nitroprusside induced hypotension: haemodynamic response and dose requirements during propofol or halothane anaesthesia.
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Blood Pressure; Cardiac Output; Female; Halo

1994
Propofol and electroconvulsive therapy.
    Anaesthesia, 1993, Volume: 48, Issue:11

    Topics: Anesthesia, General; Contraindications; Electroconvulsive Therapy; Humans; Hypertension; Methohexita

1993
Effectiveness of a manually controlled infusion scheme of propofol and alfentanil mixture for endotracheal intubation in hypertensive patients: in comparison with thiamylal and nifedipine plus thiamylal.
    Acta anaesthesiologica Sinica, 1996, Volume: 34, Issue:1

    Topics: Aged; Alfentanil; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypertension

1996
[Circulatory changes at the time of anesthetic induction and endotracheal intubation--comparison of thiamylal induction group and propofol induction group].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:10

    Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Female; Humans; H

1998
[Treatment of the hypertensive response during coronary surgery: comparison of high-dose propofol to propofol with nitroprusside].
    Revista espanola de anestesiologia y reanimacion, 1998, Volume: 45, Issue:8

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Antihypertensive Agents; Cardiac Surgical P

1998
Clonidine and cardiac surgery: haemodynamic and metabolic effects, myocardial ischaemia and recovery.
    Anaesthesia and intensive care, 1999, Volume: 27, Issue:2

    Topics: Adrenergic alpha-Agonists; Aged; Anesthetics, Intravenous; Clonidine; Coronary Artery Bypass; Creati

1999
Propofol, but not etomidate, reduces desflurane-mediated sympathetic activation in humans.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:4

    Topics: Adult; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Desf

1999
The effect of propofol and thiamylal on hypertensive responses to a rapid increase in isoflurane concentration.
    Journal of clinical anesthesia, 1999, Volume: 11, Issue:1

    Topics: Adult; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Dose-Response Relati

1999
[Changes of arterial blood pressure and heart rate during induction of anesthesia with propofol--efficacy of propofol titration using bispectral index as an indicator].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Electroe

1999
[Cardiovascular responses during laryngeal mask airway insertion in normotensive, hypertensive and chronic renal failure patients].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:8

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Hemodynamics; Humans; Hypertension;

1999
[The value of monitoring the bispectral index of the EEG for the management of hypertension during laparoscopic surgery].
    Annales francaises d'anesthesie et de reanimation, 2000, Volume: 19, Issue:8

    Topics: Anesthetics, Intravenous; Blood Pressure; Decision Support Techniques; Electroencephalography; Femal

2000
Clinical comparison of either small doses of fentanyl or remifentanil for blunting cardiovascular changes induced by tracheal intubation.
    Minerva anestesiologica, 2000, Volume: 66, Issue:10

    Topics: Anesthesia, General; Anesthetics, Intravenous; Atracurium; Blood Pressure; Female; Fentanyl; Heart R

2000
Induction with propofol target-concentration infusion vs. 8% sevoflurane inhalation and alfentanil in hypertensive patients.
    Anaesthesia, 2001, Volume: 56, Issue:3

    Topics: Aged; Alfentanil; Analgesics, Opioid; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, In

2001

Other Studies

47 other studies available for propofol and Hypertension

ArticleYear
A 67-Year-Old Woman With Fluctuating Hypertension and Hypotension After Elective Surgery.
    Chest, 2023, Volume: 163, Issue:1

    Topics: Aged; Dexmedetomidine; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Hypotension; Neuromu

2023
Effects of Propofol Combined with Sufentanil Target-Controlled Intravenous Anesthesia on Expression of Bax, Bcl-2, and Caspase-3 Genes in Spontaneous Hypertensive Rats with Cerebral Hemorrhage: a Prospective Case-Controlled Study.
    Applied biochemistry and biotechnology, 2023, Volume: 195, Issue:10

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; bcl-2-Associated X Protein; Caspase 3; C

2023
5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats.
    Journal of pharmacological sciences, 2023, Volume: 152, Issue:1

    Topics: Aminolevulinic Acid; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Bupivacaine; Hype

2023
Successful management of suspected propofol dependence with phenobarbital in an adult patient with COVID-19.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2023, 09-22, Volume: 80, Issue:19

    Topics: Adult; COVID-19; Dexmedetomidine; Fentanyl; Humans; Hypertension; Hypnotics and Sedatives; Male; Mid

2023
Safety of geriatric patients undergoing endobronchial ultrasound-guided transbronchial needle aspiration with deep sedation: a retrospective study.
    BMC anesthesiology, 2023, 08-16, Volume: 23, Issue:1

    Topics: Aged; Anesthesia, General; Deep Sedation; Female; Humans; Hypertension; Hypnotics and Sedatives; Inc

2023
Incidence of Rebound Hypertension after Discontinuation of Dexmedetomidine.
    Pharmacotherapy, 2019, Volume: 39, Issue:10

    Topics: Critical Care; Dexmedetomidine; Drug Administration Schedule; Female; Humans; Hypertension; Hypnotic

2019
Angiotensin converting enzyme inhibitors enhance the hypotensive effects of propofol by increasing nitric oxide production.
    Free radical biology & medicine, 2018, 02-01, Volume: 115

    Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin Receptor Antagonists; Angiotensin-Converting En

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
Hypotension after induction of general anesthesia: occurrence, risk factors, and therapy. A prospective multicentre observational study.
    Journal of anesthesia, 2018, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Blood

2018
The hemodynamic effects of dexmedetomidine and esmolol in electroconvulsive therapy: a retrospective comparison.
    The journal of ECT, 2013, Volume: 29, Issue:4

    Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adult; Anesthetics, Intravenous; Autonomic Nervo

2013
[Retrospective evaluation of predictors and frequency of hypotension in hypertensive patients after induction of general anesthesia].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:6

    Topics: Age Factors; Aged; Anesthesia, General; Blood Pressure; Forecasting; Humans; Hypertension; Hypotensi

2014
Acute angle-closure glaucoma after general anesthesia for bone grafting.
    Anesthesia progress, 2014,Winter, Volume: 61, Issue:4

    Topics: Alveolar Ridge Augmentation; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Darkness;

2014
Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:3

    Topics: Adult; Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Cohort Studies; Comorbidity; Di

2016
[Risk analysis of cardiovascular events in elderly hypertensive patients with different risk stratification during the perioperative period].
    Zhonghua yi xue za zhi, 2015, Jul-28, Volume: 95, Issue:28

    Topics: Aged; Anesthesia, General; Cardiac Output; Cardiovascular Diseases; Coronary Artery Disease; Fentany

2015
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc

2016
Respiratory, metabolic and hemodynamic effects of clonidine in ventilated patients presenting with withdrawal syndrome.
    Intensive care medicine, 2009, Volume: 35, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Calorimetry, Indirect; Carbon Dioxide; Clonidine; Electrocardiogra

2009
[Hypertension with tachycardia caused by propofol during induction of general anesthesia].
    Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:5

    Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Humans; Hypertension; Intraoperative Complicati

2009
Plateau waves in head injured patients requiring neurocritical care.
    Neurocritical care, 2009, Volume: 11, Issue:2

    Topics: Adult; Blood Pressure; Cerebrovascular Circulation; Craniocerebral Trauma; Critical Care; Heart Rate

2009
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A

2010
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A

2010
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A

2010
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A

2010
An unusual phenomenon with entropy during induction of general anaesthesia.
    Anaesthesia and intensive care, 2010, Volume: 38, Issue:1

    Topics: Adrenergic beta-Antagonists; Amlodipine; Anesthesia, General; Anesthetics, Intravenous; Antihyperten

2010
A prospective assessment of sedation-related adverse events and patient and endoscopist satisfaction in ERCP with anesthesiologist-administered sedation.
    Gastrointestinal endoscopy, 2011, Volume: 73, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthetics, Intravenous; Ar

2011
[Changes in the bispectral index during heart arrest and extracorporeal circulation].
    Revista espanola de anestesiologia y reanimacion, 2011, Volume: 58, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Aortic Valve Insufficiency; Cerebrovascul

2011
Accidental intraventricular administration of phenytoin through an external ventricular drain: case report.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2011, Volume: 20, Issue:4

    Topics: Anticonvulsants; Drug Administration Routes; Humans; Hypertension; Male; Medical Errors; Middle Aged

2011
Role of L-type calcium channels in altered microvascular responses to propofol in hypertension.
    British journal of anaesthesia, 2012, Volume: 108, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2012
Nurse administered propofol sedation for pulmonary endoscopies requires a specific protocol.
    Danish medical journal, 2012, Volume: 59, Issue:8

    Topics: Adult; Aged; Attitude of Health Personnel; Bronchoscopy; Deep Sedation; Endosonography; Humans; Hype

2012
Baroreflex sensitivity variations in response to propofol anesthesia: comparison between normotensive and hypertensive patients.
    Journal of clinical monitoring and computing, 2013, Volume: 27, Issue:4

    Topics: Aged; Algorithms; Anesthesia; Anesthetics, Intravenous; Arterial Pressure; Baroreflex; Blood Pressur

2013
Propofol differently alters vascular reactivity in normotensive and hypertensive rats.
    Clinical and experimental pharmacology & physiology, 2002, Volume: 29, Issue:11

    Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; In

2002
Effects of propofol compared to thiopentoneon preventing hemodynamic response to tracheal intubation.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2000, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Hemodynamics; Humans; Hypertension; Intubation, I

2000
Anaesthesia for a girl with severe hypertension due to 11 beta-hydroxylase deficiency.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:5

    Topics: Adrenal Hyperplasia, Congenital; Anesthesia, Epidural; Anesthetics, Inhalation; Anesthetics, Intrave

2003
Effect of propofol on vasoconstriction and calcium mobilization induced by Angiotensin II differs in aortas from normotensive and hypertensive rats.
    Clinical and experimental pharmacology & physiology, 2004, Volume: 31, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium; Dose-Response Relationship, Drug;

2004
Differential effects of propofol, ketamine, and thiopental anaesthesia on the skeletal muscle microcirculation of normotensive and hypertensive rats in vivo.
    British journal of anaesthesia, 2004, Volume: 93, Issue:2

    Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Arterioles; Dose-Response Relationship

2004
Difficult extubation: calming the sympathetic storm.
    Anaesthesia and intensive care, 2004, Volume: 32, Issue:3

    Topics: Aged; Conscious Sedation; Device Removal; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedat

2004
Hypertensive crisis secondary to pheochromocytoma during routine knee surgery.
    The journal of knee surgery, 2004, Volume: 17, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Anesthetics, Intravenous; Arthroscopy; Fentanyl; Humans; Hypertensio

2004
[Severe hypotension after induction of general anesthesia in a patient receiving an angiotensin II receptor antagonist and an alpha-blocker].
    Masui. The Japanese journal of anesthesiology, 2005, Volume: 54, Issue:6

    Topics: Adrenergic alpha-Antagonists; Anesthesia, General; Angiotensin II Type 1 Receptor Blockers; Antihype

2005
Phentermine and anaesthesia.
    Anaesthesia and intensive care, 2005, Volume: 33, Issue:4

    Topics: Alfentanil; Androstanols; Anesthesia; Anesthetics, Intravenous; Appetite Depressants; Blood Pressure

2005
Correlation and comparison of body mass index on hemodynamics in hypertensive and normotensive patients undergoing intravenous sedation.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2006, Volume: 64, Issue:4

    Topics: Adult; Anesthesia, Dental; Anesthetics, Intravenous; Blood Pressure; Body Mass Index; Conscious Seda

2006
Use of the Esophageal Doppler Machine to help guide the intraoperative management of two children with pheochromocytoma.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:8

    Topics: Adolescent; Adrenal Gland Neoplasms; Anesthesia, General; Anesthetics; Esophagus; Female; Humans; Hy

2006
Additive effect of propofol for attenuation of hypertension in a patient with undiagnosed phaeochromocytoma.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:6

    Topics: Adrenal Gland Neoplasms; Anesthesia, General; Female; Humans; Hypertension; Hypnotics and Sedatives;

2007
Additive effect of propofol for attenuation of hypertension in a patient with undiagnosed phaeochromocytoma.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Anesthesia, General; Blood Pressure; Drug Syne

2008
Severe hypertension and bradycardia after dexmedetomidine for radiology sedation in a patient with acute transverse myelitis.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:7

    Topics: Adjuvants, Anesthesia; Adolescent; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Blood Pressur

2008
Total intravenous anesthesia using propofol and alfentanil for coronary artery bypass surgery.
    Journal of cardiothoracic and vascular anesthesia, 1994, Volume: 8, Issue:3

    Topics: Adult; Aged; Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Awareness; Blood Press

1994
[Treatment of intraoperative status asthmaticus with ketamine].
    Anaesthesiologie und Reanimation, 1994, Volume: 19, Issue:3

    Topics: Airway Resistance; Alfentanil; Anesthesia, General; Breast Neoplasms; Female; Humans; Hypertension;

1994
Effects of propofol on vascular reactivity in isolated aortae from normotensive and spontaneously hypertensive rats.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Aorta, Thoracic; Culture Techniques; Dose-Response Relationship,

1999
The effect of propofol on angiotensin II-induced Ca(2+) mobilization in aortic smooth muscle cells from normotensive and hypertensive rats.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:3

    Topics: Anesthetics, Intravenous; Angiotensin II; Animals; Calcium; Cells, Cultured; Dose-Response Relations

2000
Severe hypertension following ephedrine administration in a patient receiving entacapone.
    Anesthesiology, 2000, Volume: 93, Issue:6

    Topics: Aged; Anesthetics, Intravenous; Antihypertensive Agents; Antiparkinson Agents; Catechols; Drug Inter

2000
Arterial baroreflex attenuation during and after continuous propofol infusion.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:9

    Topics: Animals; Arteries; Blood Pressure; Heart Rate; Hypertension; Hypotension; Infusions, Intravenous; In

1992
Sedation after cardiac bypass surgery: comparison of propofol and midazolam in the presence of a computerized closed loop arterial pressure controller.
    British journal of anaesthesia, 1992, Volume: 68, Issue:1

    Topics: Adult; Aged; Coronary Artery Bypass; Humans; Hypertension; Hypnotics and Sedatives; Midazolam; Middl

1992
Interaction between enalapril and propofol.
    Anaesthesia and intensive care, 1989, Volume: 17, Issue:4

    Topics: Adult; Anesthesia, Intravenous; Blood Pressure; Drug Synergism; Enalapril; Humans; Hypertension; Mal

1989