propofol has been researched along with Hypersensitivity in 6 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Some reports showed allergic reaction to propofol." | 5.17 | Propofol results in higher incidence of bronchoconstriction in allergic patients. ( Nishiyama, T, 2013) |
| "Propofol was found to show a similar incidence of histamine release during the induction of anesthesia using midazolam-ketamine, and thus was also found to be a useful induction agent against histamine release for patients with a history of allergy when hydroxizine was used as a premedication." | 2.69 | Histamine release during the induction of anesthesia with propofol in allergic patients: a comparison with the induction of anesthesia using midazolam-ketamine. ( Adachi, M; Kimura, K; Kubo, K, 1999) |
| "Propofol is an intravenous sedative used in many patient populations and care settings." | 1.62 | New perspectives on propofol allergy. ( Bounds, M; Hawthorne, A; Johnson, JL; Weldon, DJ, 2021) |
| "Any anaphylactoid reaction has to be systematically reported (e." | 1.29 | [Use of Diprivan in allergic patient]. ( Laxenaire, MC, 1994) |
| "Histamine was released in four controls with weak dilutions (1/2 to 10(-5)) of Diprivan (n = 2) and thiopental (n = 2)." | 1.28 | Basophil histamine release in atopic patients after in vitro provocation with thiopental, Diprivan and chlormethiazole. ( Guéant, JL; Haberer, JP; Laxenaire, MC; Mata, E; Moneret-Vautrin, DA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, JL | 1 |
| Hawthorne, A | 1 |
| Bounds, M | 1 |
| Weldon, DJ | 1 |
| Cakir, H | 1 |
| Donmez, K | 1 |
| Yurekli, I | 1 |
| Kestelli, M | 1 |
| Cakir, P | 1 |
| Nishiyama, T | 1 |
| Laxenaire, MC | 2 |
| Kimura, K | 1 |
| Adachi, M | 1 |
| Kubo, K | 1 |
| Mata, E | 1 |
| Guéant, JL | 1 |
| Moneret-Vautrin, DA | 1 |
| Haberer, JP | 1 |
2 trials available for propofol and Hypersensitivity
| Article | Year |
|---|---|
Propofol results in higher incidence of bronchoconstriction in allergic patients.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Bronchoconstriction; Female; Humans; Hyper | 2013 |
Histamine release during the induction of anesthesia with propofol in allergic patients: a comparison with the induction of anesthesia using midazolam-ketamine.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Double-Blind Me | 1999 |
4 other studies available for propofol and Hypersensitivity
| Article | Year |
|---|---|
New perspectives on propofol allergy.
Topics: Humans; Hypersensitivity; Propofol | 2021 |
What Are the First-Line Anesthetic Agents in Case of Propofol and Remifentanyl Allergy?
Topics: Anesthesia, General; Anesthetics; Cardiopulmonary Bypass; Humans; Hypersensitivity; Mitral Valve; Pr | 2019 |
[Use of Diprivan in allergic patient].
Topics: Anaphylaxis; Anesthesia, Intravenous; Contraindications; Histamine Release; Humans; Hypersensitivity | 1994 |
Basophil histamine release in atopic patients after in vitro provocation with thiopental, Diprivan and chlormethiazole.
Topics: Basophils; Chlormethiazole; Dose-Response Relationship, Drug; Fat Emulsions, Intravenous; Histamine; | 1991 |