propofol has been researched along with Hyperlipemia in 15 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This anesthetic drug may cause a rare condition named propofol infusion syndrome, characterized by unexplained lactic acidosis, lipemia, rhabdomyolysis, cardiovascular collapse and Brugada-like electrocardiographic pattern or Brugada electrocardiographic phenocopy changes following high-dose propofol infusion over prolonged periods of time." | 8.86 | Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. ( Dubner, S; Ferreira, C; Filho, CF; Riera, AR; Schapachnik, E; Uchida, AH, 2010) |
| "Propofol infusion syndrome (PRIS) is defined as acute bradycardia progressing to asystole combined with lipemic plasma, fatty liver enlargement, metabolic acidosis with negative base excess >10 mmol l(-1), rhabdomyolysis or myoglobinuria associated with propofol infusion." | 8.85 | Propofol infusion syndrome: update of clinical manifestation and pathophysiology. ( Bein, B; Fudickar, A, 2009) |
| "Propofol infusion syndrome is a rare but often fatal syndrome, characterized by lactacidosis, lipaemic plasma and cardiac failure, associated with propofol infusion over prolonged periods of time." | 8.83 | Propofol infusion syndrome in anaesthesia and intensive care medicine. ( Bein, B; Fudickar, A; Tonner, PH, 2006) |
| "Propofol has been associated with severe adverse reactions in children receiving intensive care." | 6.40 | Lactic acidemia and bradyarrhythmia in a child sedated with propofol. ( Cox, PN; Cray, SH; Robinson, BH, 1998) |
| "Reports of intraoperative lipemia during propofol anesthesia are very rare but raise concerns about the safety of prolonged propofol infusion." | 5.40 | Hypertriglyceridemia, lipemia, and elevated liver enzymes associated with prolonged propofol anesthesia for craniotomy. ( Bowdle, A; Gabikian, P; Lee, L; Richebe, P; Rostomily, R, 2014) |
| "Propofol infusion syndrome is a rare but frequently fatal complication in critically ill children who are given prolonged high-dose infusions of the drug." | 5.34 | Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury. ( Coritsidis, G; Rehman, Z; Sabsovich, I; Yunen, J, 2007) |
| "This anesthetic drug may cause a rare condition named propofol infusion syndrome, characterized by unexplained lactic acidosis, lipemia, rhabdomyolysis, cardiovascular collapse and Brugada-like electrocardiographic pattern or Brugada electrocardiographic phenocopy changes following high-dose propofol infusion over prolonged periods of time." | 4.86 | Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. ( Dubner, S; Ferreira, C; Filho, CF; Riera, AR; Schapachnik, E; Uchida, AH, 2010) |
| "Propofol infusion syndrome (PRIS) is defined as acute bradycardia progressing to asystole combined with lipemic plasma, fatty liver enlargement, metabolic acidosis with negative base excess >10 mmol l(-1), rhabdomyolysis or myoglobinuria associated with propofol infusion." | 4.85 | Propofol infusion syndrome: update of clinical manifestation and pathophysiology. ( Bein, B; Fudickar, A, 2009) |
| "Propofol infusion syndrome is a rare but often fatal syndrome, characterized by lactacidosis, lipaemic plasma and cardiac failure, associated with propofol infusion over prolonged periods of time." | 4.83 | Propofol infusion syndrome in anaesthesia and intensive care medicine. ( Bein, B; Fudickar, A; Tonner, PH, 2006) |
| "Propofol was extensively bound to the three lipoprotein fractions (88%+/-2% to VLDL, 93%+/-1% to LDL, and 91%+/-4% to HDL)." | 2.69 | The significance of lipoproteins in serum binding variations of propofol. ( Aguirre, C; Calvo, R; García, E; Suárez, E; Zamacona, MK, 1998) |
| "Midazolam can also cause paradoxical reactions, including increased agitation, poor co-operation and aggressive or violent behaviour, which has been successfully managed with flumazenil." | 2.42 | Toxicity of intravenous anaesthetics. ( Short, TG; Young, Y, 2003) |
| "Propofol has been associated with severe adverse reactions in children receiving intensive care." | 2.40 | Lactic acidemia and bradyarrhythmia in a child sedated with propofol. ( Cox, PN; Cray, SH; Robinson, BH, 1998) |
| "Propofol was infused at 1." | 1.91 | Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS. ( Babu, VK; Garcia-Fernandez, A; Perez Del Nogal, G; Rojas, P, 2023) |
| " Despite adequate dosing of both intravenous and inhalation anesthetics, our patient was resistant to induction of the state of general anesthesia." | 1.43 | Hyperlipidemia sink for anesthetic agents. ( Eldesouki, E; Hobika, GG; Johnson, TJ; Nader, ND; Porhomayon, J; Smith, K, 2016) |
| "Reports of intraoperative lipemia during propofol anesthesia are very rare but raise concerns about the safety of prolonged propofol infusion." | 1.40 | Hypertriglyceridemia, lipemia, and elevated liver enzymes associated with prolonged propofol anesthesia for craniotomy. ( Bowdle, A; Gabikian, P; Lee, L; Richebe, P; Rostomily, R, 2014) |
| "Propofol infusion syndrome is a rare but frequently fatal complication in critically ill children who are given prolonged high-dose infusions of the drug." | 1.34 | Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury. ( Coritsidis, G; Rehman, Z; Sabsovich, I; Yunen, J, 2007) |
| "Propofol is an intravenous agent used in anesthesia." | 1.33 | Propofol lipemia mimicking chyle leak during neck dissection. ( Armstrong, WB; Linskey, ME; Vokes, DE, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Babu, VK | 1 |
| Rojas, P | 1 |
| Perez Del Nogal, G | 1 |
| Garcia-Fernandez, A | 1 |
| Bowdle, A | 1 |
| Richebe, P | 1 |
| Lee, L | 1 |
| Rostomily, R | 1 |
| Gabikian, P | 1 |
| Johnson, TJ | 1 |
| Porhomayon, J | 1 |
| Nader, ND | 1 |
| Eldesouki, E | 1 |
| Smith, K | 1 |
| Hobika, GG | 1 |
| Fudickar, A | 2 |
| Bein, B | 2 |
| Devlin, JW | 1 |
| Mallow-Corbett, S | 1 |
| Riker, RR | 1 |
| Riera, AR | 1 |
| Uchida, AH | 1 |
| Schapachnik, E | 1 |
| Dubner, S | 1 |
| Filho, CF | 1 |
| Ferreira, C | 1 |
| Coetzee, A | 1 |
| Blaine, EM | 1 |
| Labadarios, D | 1 |
| Schall, R | 1 |
| Haus, M | 1 |
| Crawford, MW | 1 |
| Dodgson, BG | 1 |
| Holtby, HH | 1 |
| Roy, WL | 1 |
| Short, TG | 1 |
| Young, Y | 1 |
| Tonner, PH | 1 |
| Vokes, DE | 1 |
| Linskey, ME | 1 |
| Armstrong, WB | 1 |
| Sabsovich, I | 1 |
| Rehman, Z | 1 |
| Yunen, J | 1 |
| Coritsidis, G | 1 |
| Zamacona, MK | 1 |
| Suárez, E | 1 |
| García, E | 1 |
| Aguirre, C | 1 |
| Calvo, R | 1 |
| Susla, GM | 1 |
| Cray, SH | 1 |
| Robinson, BH | 1 |
| Cox, PN | 1 |
7 reviews available for propofol and Hyperlipemia
| Article | Year |
|---|---|
Propofol infusion syndrome: update of clinical manifestation and pathophysiology.
Topics: Acidosis; Acute Disease; Adult; Age Factors; Anesthetics, Intravenous; Animals; Bradycardia; Brain I | 2009 |
Adverse drug events associated with the use of analgesics, sedatives, and antipsychotics in the intensive care unit.
Topics: Acidosis; Analgesics; Antipsychotic Agents; Bradycardia; Cardiovascular Diseases; Critical Care; Dru | 2010 |
Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy.
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Animals; Brugada Syndrome; Electrocardiography; Heart Co | 2010 |
Toxicity of intravenous anaesthetics.
Topics: Anesthetics, Intravenous; Humans; Hyperlipidemias; Ketamine; Midazolam; Nervous System; Pancreatitis | 2003 |
Propofol infusion syndrome in anaesthesia and intensive care medicine.
Topics: Acidosis; Anesthesia; Anesthetics, Intravenous; Critical Care; Heart Failure; Humans; Hyperlipidemia | 2006 |
Propofol toxicity in critically ill pediatric patients: show us the proof.
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Bradycardia; Child; Child, Preschool; Conscious Sedation | 1998 |
Lactic acidemia and bradyarrhythmia in a child sedated with propofol.
Topics: Acidosis, Lactic; Bradycardia; Conscious Sedation; Fatty Liver; Humans; Hyperlipidemias; Hypnotics a | 1998 |
2 trials available for propofol and Hyperlipemia
| Article | Year |
|---|---|
Effect of 1% and 2% propofol on blood lipids during longterm sedation.
Topics: Adult; Aged; Anesthesia, General; Cholesterol; Dose-Response Relationship, Drug; Female; Humans; Hyp | 2002 |
The significance of lipoproteins in serum binding variations of propofol.
Topics: Adult; Anesthetics, Intravenous; Cholesterol; Chromatography, High Pressure Liquid; Female; Humans; | 1998 |
6 other studies available for propofol and Hyperlipemia
| Article | Year |
|---|---|
Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS.
Topics: Acidosis; Aged; COVID-19; Humans; Hyperlipidemias; Hypertriglyceridemia; Male; Propofol; Propofol In | 2023 |
Hypertriglyceridemia, lipemia, and elevated liver enzymes associated with prolonged propofol anesthesia for craniotomy.
Topics: Adult; Alanine Transaminase; Anesthetics, Intravenous; Aspartate Aminotransferases; Craniotomy; Drug | 2014 |
Hyperlipidemia sink for anesthetic agents.
Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrav | 2016 |
Propofol syndrome in children.
Topics: Acidosis; Age Factors; Anesthetics, Intravenous; Child; Conscious Sedation; Critical Illness; Hepato | 2003 |
Propofol lipemia mimicking chyle leak during neck dissection.
Topics: Anesthetics, Intravenous; Chyle; Diagnosis, Differential; Humans; Hyperlipidemias; Intraoperative Co | 2006 |
Propofol infusion syndrome: a case of increasing morbidity with traumatic brain injury.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Anesthetics, Intravenous; Brain Injuries; Fatal Outcome; | 2007 |