propofol has been researched along with Hemorrhagic Shock in 18 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol and fentanyl preconditioning can protect the heart against acute ischemia and promote the recovery of hemodynamics during hemorrhagic shock." | 7.75 | Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock. ( Chai, W; Kuai, J; Liu, X; Tao, L; Yang, Y; Yao, L; Yu, D; Zeng, X, 2009) |
| "Propofol can ameliorate the lowering of corticosteroid secretion, moderate inflammatory response, and protect vital organs in rats with hemorrhagic shock." | 7.75 | [The influences of propofol on corticosteroid and immunity of rats after hemorrhagic shock and resuscitation]. ( Cao, SH; Ji, X, 2009) |
| "Hemorrhagic shock increases the hypnotic effect of propofol, but the influence of hemorrhagic shock on the immobilizing effect of propofol is not fully defined." | 7.75 | The influence of hemorrhagic shock on the electroencephalographic and immobilizing effects of propofol in a swine model. ( Katoh, T; Kurita, T; Morishima, Y; Morita, K; Sato, S; Takata, K; Uraoka, M, 2009) |
| "Propofol can attenuate the gastric mucosa injury by eliminating oxygen free radical and preventing its generation caused by hemorrhagic shock and reperfusion." | 7.74 | [Effect of propofol on gastric mucosal injury after hemorrhagic shock and reperfusion in rabbits]. ( Li, HY; Lü, YX; Wang, LL; Zhang, LF, 2008) |
| "Hemorrhagic shock altered the pharmacokinetics and pharmacodynamics of propofol." | 7.72 | The influence of hemorrhagic shock on propofol: a pharmacokinetic and pharmacodynamic analysis. ( Church, T; Egan, TD; Johnson, KB; Kern, SE; McJames, SW; Syroid, N; Whiddon, D; White, JL, 2003) |
| "Previous work has demonstrated that ongoing hemorrhagic shock dramatically alters the distribution, clearance, and potency of propofol." | 7.72 | Influence of hemorrhagic shock followed by crystalloid resuscitation on propofol: a pharmacokinetic and pharmacodynamic analysis. ( Cluff, ML; Egan, TD; Johnson, KB; Kern, SE; McJames, SW; Pace, NL, 2004) |
| " Hemorrhage of less than 600 ml (19 ml/kg) was not accompanied by a significant change in plasma propofol concentration." | 7.71 | Influence of hemorrhage on propofol pseudo-steady state concentration. ( Kazama, T; Kurita, T; Morita, K; Nakata, J; Sato, S, 2002) |
| "Propofol remarkably relieves the lung injury occurring during hemorrhagic shock and resuscitation stage by ameliorating pulmonary circulation." | 7.71 | [Effect of propofol on protecting Rhesus macaques from reperfusion lung injury during hemorrhagic shock and resuscitation]. ( Huang, X; Song, Q; Wang, M; Zhang, H, 2002) |
| "Posttreatment propofol decreased serum TNF-alpha level, increased serum IL-10 level, attenuated the severity of organ damage, and improved survival rate after HS." | 5.35 | Propofol protects against hemorrhagic shock-induced organ damage in conscious spontaneously hypertensive rats. ( Hsu, BG; Lee, CC; Lee, CJ; Lee, RP; Peng, TC; Subeq, YM, 2009) |
| "Propofol and fentanyl preconditioning can protect the heart against acute ischemia and promote the recovery of hemodynamics during hemorrhagic shock." | 3.75 | Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock. ( Chai, W; Kuai, J; Liu, X; Tao, L; Yang, Y; Yao, L; Yu, D; Zeng, X, 2009) |
| "Propofol can ameliorate the lowering of corticosteroid secretion, moderate inflammatory response, and protect vital organs in rats with hemorrhagic shock." | 3.75 | [The influences of propofol on corticosteroid and immunity of rats after hemorrhagic shock and resuscitation]. ( Cao, SH; Ji, X, 2009) |
| "Hemorrhagic shock increases the hypnotic effect of propofol, but the influence of hemorrhagic shock on the immobilizing effect of propofol is not fully defined." | 3.75 | The influence of hemorrhagic shock on the electroencephalographic and immobilizing effects of propofol in a swine model. ( Katoh, T; Kurita, T; Morishima, Y; Morita, K; Sato, S; Takata, K; Uraoka, M, 2009) |
| "Propofol can attenuate the gastric mucosa injury by eliminating oxygen free radical and preventing its generation caused by hemorrhagic shock and reperfusion." | 3.74 | [Effect of propofol on gastric mucosal injury after hemorrhagic shock and reperfusion in rabbits]. ( Li, HY; Lü, YX; Wang, LL; Zhang, LF, 2008) |
| "Hemorrhagic shock altered the pharmacokinetics and pharmacodynamics of propofol." | 3.72 | The influence of hemorrhagic shock on propofol: a pharmacokinetic and pharmacodynamic analysis. ( Church, T; Egan, TD; Johnson, KB; Kern, SE; McJames, SW; Syroid, N; Whiddon, D; White, JL, 2003) |
| "Previous work has demonstrated that ongoing hemorrhagic shock dramatically alters the distribution, clearance, and potency of propofol." | 3.72 | Influence of hemorrhagic shock followed by crystalloid resuscitation on propofol: a pharmacokinetic and pharmacodynamic analysis. ( Cluff, ML; Egan, TD; Johnson, KB; Kern, SE; McJames, SW; Pace, NL, 2004) |
| " Hemorrhage of less than 600 ml (19 ml/kg) was not accompanied by a significant change in plasma propofol concentration." | 3.71 | Influence of hemorrhage on propofol pseudo-steady state concentration. ( Kazama, T; Kurita, T; Morita, K; Nakata, J; Sato, S, 2002) |
| "Propofol remarkably relieves the lung injury occurring during hemorrhagic shock and resuscitation stage by ameliorating pulmonary circulation." | 3.71 | [Effect of propofol on protecting Rhesus macaques from reperfusion lung injury during hemorrhagic shock and resuscitation]. ( Huang, X; Song, Q; Wang, M; Zhang, H, 2002) |
| "The physiologic changes during hemorrhagic shock can alter pharmacokinetics and pharmacodynamics of intravenous anesthetics." | 2.66 | The Influence of Hemorrhagic Shock on the Disposition and Effects of Intravenous Anesthetics: A Narrative Review. ( Egan, ED; Johnson, KB, 2020) |
| "Posttreatment propofol decreased serum TNF-alpha level, increased serum IL-10 level, attenuated the severity of organ damage, and improved survival rate after HS." | 1.35 | Propofol protects against hemorrhagic shock-induced organ damage in conscious spontaneously hypertensive rats. ( Hsu, BG; Lee, CC; Lee, CJ; Lee, RP; Peng, TC; Subeq, YM, 2009) |
| "1." | 1.35 | Low-dose propofol ameliorates haemorrhagic shock-induced organ damage in conscious rats. ( Hsu, BG; Lee, CJ; Lee, RP; Subeq, YM; Wu, WT, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (77.78) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Egan, ED | 1 |
| Johnson, KB | 3 |
| Yao, L | 1 |
| Kuai, J | 1 |
| Liu, X | 1 |
| Yu, D | 1 |
| Yang, Y | 1 |
| Tao, L | 1 |
| Zeng, X | 1 |
| Chai, W | 1 |
| Lee, CJ | 2 |
| Lee, RP | 2 |
| Subeq, YM | 2 |
| Lee, CC | 1 |
| Peng, TC | 1 |
| Hsu, BG | 2 |
| Ji, X | 1 |
| Cao, SH | 1 |
| Kurita, T | 3 |
| Takata, K | 1 |
| Morita, K | 3 |
| Morishima, Y | 2 |
| Uraoka, M | 2 |
| Katoh, T | 1 |
| Sato, S | 3 |
| Brezina, A | 1 |
| Drabek, T | 1 |
| Riha, H | 1 |
| Schreiberova, J | 1 |
| Hess, L | 1 |
| Cavus, E | 1 |
| Meybohm, P | 1 |
| Doerges, V | 1 |
| Hoecker, J | 1 |
| Betz, M | 1 |
| Hanss, R | 1 |
| Steinfath, M | 1 |
| Bein, B | 1 |
| Suzuki, M | 1 |
| Kazama, T | 1 |
| Nakata, J | 1 |
| Song, Q | 1 |
| Wang, M | 1 |
| Huang, X | 1 |
| Zhang, H | 1 |
| Egan, TD | 2 |
| Kern, SE | 2 |
| White, JL | 1 |
| McJames, SW | 2 |
| Syroid, N | 1 |
| Whiddon, D | 1 |
| Church, T | 1 |
| Shafer, SL | 1 |
| Cluff, ML | 1 |
| Pace, NL | 1 |
| Takizawa, D | 2 |
| Sato, E | 1 |
| Kurosaki, D | 1 |
| Hiraoka, H | 2 |
| Horiuchi, R | 1 |
| Goto, F | 1 |
| Lichtor, JL | 1 |
| Takizawa, E | 1 |
| Miyoshi, S | 1 |
| Kawahara, F | 1 |
| Wu, WT | 1 |
| Lü, YX | 1 |
| Zhang, LF | 1 |
| Wang, LL | 1 |
| Li, HY | 1 |
1 review available for propofol and Hemorrhagic Shock
| Article | Year |
|---|---|
The Influence of Hemorrhagic Shock on the Disposition and Effects of Intravenous Anesthetics: A Narrative Review.
Topics: Aged; Alfentanil; Anesthetics, Intravenous; Animals; Blood Pressure; Etomidate; Female; Humans; Infu | 2020 |
17 other studies available for propofol and Hemorrhagic Shock
| Article | Year |
|---|---|
Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock.
Topics: Anesthetics, Intravenous; Animals; Female; Fentanyl; Hemodynamics; Ischemic Preconditioning, Myocard | 2009 |
Propofol protects against hemorrhagic shock-induced organ damage in conscious spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Interleukin-10; Kaplan-Meier Est | 2009 |
[The influences of propofol on corticosteroid and immunity of rats after hemorrhagic shock and resuscitation].
Topics: Animals; Disease Models, Animal; Hydrocortisone; Interferon-gamma; Interleukin-4; Intestine, Small; | 2009 |
The influence of hemorrhagic shock on the electroencephalographic and immobilizing effects of propofol in a swine model.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Cardiac Output; Electroe | 2009 |
The effect of medetomidine-ketamine anesthesia on hemodynamic parameters during hemorrhagic shock in minipigs.
Topics: Anesthesia; Anesthetics, Dissociative; Animals; Blood Pressure; Blood Volume; Cardiac Output; Heart | 2010 |
Effects of cerebral hypoperfusion on bispectral index: a randomised, controlled animal experiment during haemorrhagic shock.
Topics: Anesthetics, Intravenous; Animals; Arginine Vasopressin; Blood Flow Velocity; Blood Pressure; Brain; | 2010 |
Influence of haemorrhage on the pseudo-steady-state remifentanil concentration in a swine model: a comparison with propofol and the effect of haemorrhagic shock stage.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Blood Pressure; Blood Volume; Cardiac Outpu | 2011 |
Influence of hemorrhage on propofol pseudo-steady state concentration.
Topics: Anesthetics, Intravenous; Animals; Cardiac Output; Female; Hemodynamics; Hemorrhage; Male; Metabolic | 2002 |
[Effect of propofol on protecting Rhesus macaques from reperfusion lung injury during hemorrhagic shock and resuscitation].
Topics: Animals; Anticonvulsants; Lactates; Lung; Lung Diseases; Macaca mulatta; Male; Malondialdehyde; Prop | 2002 |
The influence of hemorrhagic shock on propofol: a pharmacokinetic and pharmacodynamic analysis.
Topics: Algorithms; Analysis of Variance; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Ani | 2003 |
Shock values.
Topics: Anesthetics, Intravenous; Animals; Cardiopulmonary Resuscitation; Humans; Propofol; Shock, Hemorrhag | 2004 |
Influence of hemorrhagic shock followed by crystalloid resuscitation on propofol: a pharmacokinetic and pharmacodynamic analysis.
Topics: Algorithms; Anesthesia; Anesthetics, Intravenous; Animals; Cardiac Output; Cardiopulmonary Resuscita | 2004 |
Pharmacodynamics of propofol during hemorrhagic shock.
Topics: Anesthetics, Intravenous; Animals; Humans; Propofol; Rats; Shock, Hemorrhagic | 2005 |
Depth of anesthesia monitors and shock.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Electroencephalography; Humans; Monitoring, Intraoper | 2005 |
The increase in total and unbound propofol concentrations during accidental hemorrhagic shock in patients undergoing liver transplantation.
Topics: Blood Pressure; Heart Rate; Humans; Liver Transplantation; Propofol; Protein Binding; Shock, Hemorrh | 2006 |
Low-dose propofol ameliorates haemorrhagic shock-induced organ damage in conscious rats.
Topics: Animals; Consciousness; Male; Multiple Organ Failure; Propofol; Rats; Rats, Inbred WKY; Shock, Hemor | 2008 |
[Effect of propofol on gastric mucosal injury after hemorrhagic shock and reperfusion in rabbits].
Topics: Animals; Disease Models, Animal; Gastric Mucosa; Male; Malondialdehyde; Propofol; Rabbits; Random Al | 2008 |